2013-06-12_18:15:15-pubTable.tsv

Authors	Title	Journal	Vol:Issue:Page	Year	Pubmed_Id	Citation_Number	Authors_Full_Name	First_Author	LastAuthor	Affiliations	Grants
Cheng P, Andersen P, Hassel D, Kaynak BL, Limphong P, Juergensen L, Kwon C, Srivastava D	Fibronectin mediates mesendodermal cell fate decisions.	Development	140:12:2587-96	2013	23715551		Paul Cheng, Peter Andersen, David Hassel, Bogac L Kaynak, Pattraranee Limphong, Lonny Juergensen, Chulan Kwon, Deepak Srivastava	Paul Cheng	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NA
Qian L, Berry EC, Fu JD, Ieda M, Srivastava D	Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro.	Nat Protoc	8:6:1204-15	2013	23722259		Li Qian, Emily C Berry, Ji-Dong Fu, Masaki Ieda, Deepak Srivastava	Li Qian	Deepak Srivastava	1] Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA. [2] Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, California, USA. [3] Department of Pediatrics, University of California, San Francisco, California, USA. [4] Department of Biochemistry and Biophysics, University of California, San Francisco, California, USA. [5].	NA
Srivastava D, Heidersbach AJ	Small Solutions to Big Problems: MicroRNAs for Cardiac Regeneration.	Circ. Res.	112:11:1412-4	2013	23704215		Deepak Srivastava, Amy J Heidersbach	Deepak Srivastava	Amy J Heidersbach	From the Gladstone Institute of Cardiovascular Disease and Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA; and Departments of Pediatrics and Biochemistry & Biophysics, University of California, San Francisco, CA.	NA
Spindler MJ, Burmeister BT, Huang Y, Hsiao EC, Salomonis N, Scott MJ, Srivastava D, Carnegie GK, Conklin BR	AKAP13 Rho-GEF and PKD-Binding Domain Deficient Mice Develop Normally but Have an Abnormal Response to β-Adrenergic-Induced Cardiac Hypertrophy.	PLoS ONE	8:4:e62705	2013	23658642		Matthew J Spindler, Brian T Burmeister, Yu Huang, Edward C Hsiao, Nathan Salomonis, Mark J Scott, Deepak Srivastava, Graeme K Carnegie, Bruce R Conklin	Matthew J Spindler	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America ; Graduate Program in Pharmaceutical Sciences and Pharmacogenomics, University of California San Francisco, San Francisco, California, United States of America.	NA
Srivastava D, Cordes Metzler KR	Fending for a braveheart.	EMBO J.	32:9:1211-3	2013	23524853		Deepak Srivastava, Kimberly R Cordes Metzler	Deepak Srivastava	Kimberly R Cordes Metzler	Gladstone Institute of Cardiovascular Disease, Roddenberry Center for Stem Cell Biology and Medicine, and Departments of Pediatrics and Biochemistry & Biophysics, University of California, San Francisco, CA, USA.	NA
Limphong P, Zhang H, Christians E, Liu Q, Riedel M, Ivey K, Cheng P, Mitzelfelt K, Taylor G, Winge D, Srivastava D, Benjamin I	Modeling human protein aggregation cardiomyopathy using murine induced pluripotent stem cells.	Stem Cells Transl Med	2:3:161-6	2013	23430692		Pattraranee Limphong, Huali Zhang, Elisabeth Christians, Qiang Liu, Michael Riedel, Kathryn Ivey, Paul Cheng, Katie Mitzelfelt, Graydon Taylor, Dennis Winge, Deepak Srivastava, Ivor Benjamin	Pattraranee Limphong	Ivor Benjamin	University of Utah School of Medicine, Salt Lake City, UT, USA.	NHLBI NIH HHS; 5R01-HL074370-03
White MP, Rufaihah AJ, Liu L, Ghebremariam YT, Ivey KN, Cooke JP, Srivastava D	Limited gene expression variation in human embryonic stem cell and induced pluripotent stem cell-derived endothelial cells.	Stem Cells	31:1:92-103	2013	23079999		Mark P White, Abdul J Rufaihah, Lei Liu, Yohannes T Ghebremariam, Kathryn N Ivey, John P Cooke, Deepak Srivastava	Mark P White	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; U01HL099775
Plath K, Srivastava D, Alvarez-Buylla A, Tanaka EM, Kriegstein AR	Stem cells in the land of the rising sun: ISSCR 2012.	Cell Stem Cell	11:5:607-14	2012	23122288		Kathrin Plath, Deepak Srivastava, Arturo Alvarez-Buylla, Elly M Tanaka, Arnold R Kriegstein	Kathrin Plath	Arnold R Kriegstein	Department of Biological Chemistry, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90024, USA.	NA
Vedantham V, Evangelista M, Huang Y, Srivastava D	Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning.	Dev. Biol.	373:1:149-62	2013	23085412		Vasanth Vedantham, Melissa Evangelista, Yu Huang, Deepak Srivastava	Vasanth Vedantham	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA. vedanthamv@medicine.ucsf.edu	NHLBI NIH HHS; U01 HL100406
Srivastava D, Ieda M, Fu J, Qian L	Cardiac repair with thymosin β4 and cardiac reprogramming factors.	Ann. N. Y. Acad. Sci.	1270:66-72	2012	23050819		Deepak Srivastava, Masaki Ieda, Jidong Fu, Li Qian	Deepak Srivastava	Li Qian	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. dsrivastava@gladstone.ucsf.edu	NHLBI NIH HHS; U01 HL100406
Wamstad JA, Alexander JM, Truty RM, Shrikumar A, Li F, Eilertson KE, Ding H, Wylie JN, Pico AR, Capra JA, Erwin G, Kattman SJ, Keller GM, Srivastava D, Levine SS, Pollard KS, Holloway AK, Boyer LA, Bruneau BG	Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage.	Cell	151:1:206-20	2012	22981692		Joseph A Wamstad, Jeffrey M Alexander, Rebecca M Truty, Avanti Shrikumar, Fugen Li, Kirsten E Eilertson, Huiming Ding, John N Wylie, Alexander R Pico, John A Capra, Genevieve Erwin, Steven J Kattman, Gordon M Keller, Deepak Srivastava, Stuart S Levine, Katherine S Pollard, Alisha K Holloway, Laurie A Boyer, Benoit G Bruneau	Joseph A Wamstad	Benoit G Bruneau	Department of Biology, Massachusetts Institute of Technology, Cambridge, 02139, USA.	NHLBI NIH HHS; U01HL098179
Hassel D, Cheng P, White MP, Ivey KN, Kroll J, Augustin HG, Katus HA, Stainier DY, Srivastava D	MicroRNA-10 regulates the angiogenic behavior of zebrafish and human endothelial cells by promoting vascular endothelial growth factor signaling.	Circ. Res.	111:11:1421-33	2012	22955733		David Hassel, Paul Cheng, Mark P White, Kathryn N Ivey, Jens Kroll, Hellmut G Augustin, Hugo A Katus, Didier Y R Stainier, Deepak Srivastava	David Hassel	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. david.hassel@med.uni-heidelberg.de	NHLBI NIH HHS; U01 HL100406
Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S	Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells.	Cell Stem Cell	11:1:91-9	2012	22770243		Kiichiro Tomoda, Kazutoshi Takahashi, Karen Leung, Aki Okada, Megumi Narita, N Alice Yamada, Kirsten E Eilertson, Peter Tsang, Shiro Baba, Mark P White, Salma Sami, Deepak Srivastava, Bruce R Conklin, Barbara Panning, Shinya Yamanaka	Kiichiro Tomoda	Shinya Yamanaka	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA 94158, USA.	NHLBI NIH HHS; U01-HL100406
Srivastava D, Ieda M	Critical factors for cardiac reprogramming.	Circ. Res.	111:1:5-8	2012	22723217		Deepak Srivastava, Masaki Ieda	Deepak Srivastava	Masaki Ieda		NHLBI NIH HHS; U01 HL100406
Qian L, Huang Y, Spencer CI, Foley A, Vedantham V, Liu L, Conway SJ, Fu JD, Srivastava D	In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.	Nature	485:7400:593-8	2012	22522929		Li Qian, Yu Huang, C Ian Spencer, Amy Foley, Vasanth Vedantham, Lei Liu, Simon J Conway, Ji-dong Fu, Deepak Srivastava	Li Qian	Deepak Srivastava	1Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; U01 HL100406
Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V	Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.	PLoS Genet.	8:5:e1002690	2012	22589735		Chaitali Misra, Nita Sachan, Caryn Rothrock McNally, Sara N Koenig, Haley A Nichols, Anuradha Guggilam, Pamela A Lucchesi, William T Pu, Deepak Srivastava, Vidu Garg	Chaitali Misra	Vidu Garg	Center for Cardiovascular and Pulmonary Research and the Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio, United States of America.	NHLBI NIH HHS; R01 HL095712
Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, de Jong PJ, Bluestone JA, Srivastava D, McManus MT	A resource for the conditional ablation of microRNAs in the mouse.	Cell Rep	1:4:385-91	2012	22570807		Chong Yon Park, Lukas T Jeker, Karen Carver-Moore, Alyssia Oh, Huey Jiin Liu, Rachel Cameron, Hunter Richards, Zhongmei Li, David Adler, Yuko Yoshinaga, Maria Martinez, Michael Nefadov, Abul K Abbas, Art Weiss, Lewis L Lanier, Pieter J de Jong, Jeffrey A Bluestone, Deepak Srivastava, Michael T McManus	Chong Yon Park	Michael T McManus	UCSF Diabetes Center, UCSF, San Francisco, CA 94143, USA.	NHLBI NIH HHS; R24 HL092851-01
Kathiresan S, Srivastava D	Genetics of human cardiovascular disease.	Cell	148:6:1242-57	2012	22424232		Sekar Kathiresan, Deepak Srivastava	Sekar Kathiresan	Deepak Srivastava	Center for Human Genetic Research and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA 02114, USA. skathiresan@partners.org	NHLBI NIH HHS; U01 HL100406-04
Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H	Tbx1 regulates oral epithelial adhesion and palatal development.	Hum. Mol. Genet.	21:11:2524-37	2012	22371266		Noriko Funato, Masataka Nakamura, James A Richardson, Deepak Srivastava, Hiromi Yanagisawa	Noriko Funato	Hiromi Yanagisawa	Human Gene Sciences Center, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.	NHLBI NIH HHS; R01 HL106305
Bernstein HS, Srivastava D	Stem cell therapy for cardiac disease.	Pediatr. Res.	71:4 Pt 2:491-9	2012	22430385		Harold S Bernstein, Deepak Srivastava	Harold S Bernstein	Deepak Srivastava	Department of Pediatrics, University of California, San Francisco, San Francisco, California, USA. harold.bernstein@ucsf.edu	NA
Roach JC, Glusman G, Hubley R, Montsaroff SZ, Holloway AK, Mauldin DE, Srivastava D, Garg V, Pollard KS, Galas DJ, Hood L, Smit AF	Chromosomal haplotypes by genetic phasing of human families.	Am. J. Hum. Genet.	89:3:382-97	2011	21855840		Jared C Roach, Gustavo Glusman, Robert Hubley, Stephen Z Montsaroff, Alisha K Holloway, Denise E Mauldin, Deepak Srivastava, Vidu Garg, Katherine S Pollard, David J Galas, Leroy Hood, Arian F A Smit	Jared C Roach	Arian F A Smit	Institute for Systems Biology, Seattle, WA 98109, USA.	NIGMS NIH HHS; R01 GM081083
Kwon C, Cheng P, King IN, Andersen P, Shenje L, Nigam V, Srivastava D	Notch post-translationally regulates β-catenin protein in stem and progenitor cells.	Nat. Cell Biol.	13:10:1244-51	2011	21841793		Chulan Kwon, Paul Cheng, Isabelle N King, Peter Andersen, Lincoln Shenje, Vishal Nigam, Deepak Srivastava	Chulan Kwon	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, San Francisco, 1650 Owens Street, San Francisco, California 94158, USA. ckwon13@jhmi.edu	NHLBI NIH HHS; U01 HL100406
AlRais F, Feldstein VA, Srivastava D, Gosnell K, Moon-Grady AJ	Monochorionic twins discordant for congenital heart disease: a referral center's experience and possible pathophysiologic mechanisms.	Prenat. Diagn.	31:10:978-84	2011	21744365		F AlRais, V A Feldstein, D Srivastava, K Gosnell, A J Moon-Grady	F AlRais	A J Moon-Grady	Feto-Maternal Medicine Unit, Al-Wasl Hospital, Dubai Health Authority, Dubai, UAE.	NA
Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R	Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.	J. Cell Biol.	193:7:1181-96	2011	21690310		Li Qian, Joshua D Wythe, Jiandong Liu, Jerome Cartry, Georg Vogler, Bhagyalaxmi Mohapatra, Robyn T Otway, Yu Huang, Isabelle N King, Marjorie Maillet, Yi Zheng, Timothy Crawley, Ouarda Taghli-Lamallem, Christopher Semsarian, Sally Dunwoodie, David Winlaw, Richard P Harvey, Diane Fatkin, Jeffrey A Towbin, Jeffery D Molkentin, Deepak Srivastava, Karen Ocorr, Benoit G Bruneau, Rolf Bodmer	Li Qian	Rolf Bodmer	Development and Aging Program, NASCR Center, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037, USA.	NHLBI NIH HHS; T32HL007731
Shieh JT, Huang Y, Gilmore J, Srivastava D	Elevated miR-499 levels blunt the cardiac stress response.	PLoS ONE	6:5:e19481	2011	21573063		Joseph T C Shieh, Yu Huang, Jacqueline Gilmore, Deepak Srivastava	Joseph T C Shieh	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America.	NHLBI NIH HHS; K08 HL092970
King IN, Qian L, Liang J, Huang Y, Shieh JT, Kwon C, Srivastava D	A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity.	Dev. Cell	20:4:497-510	2011	21497762		Isabelle N King, Li Qian, Jianping Liang, Yu Huang, Joseph T C Shieh, Chulan Kwon, Deepak Srivastava	Isabelle N King	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. iking@gladstone.ucsf.edu	NHLBI NIH HHS; R01 HL080592-06
Fish JE, Wythe JD, Xiao T, Bruneau BG, Stainier DY, Srivastava D, Woo S	A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish.	Development	138:7:1409-19	2011	21385766		Jason E Fish, Joshua D Wythe, Tong Xiao, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava, Stephanie Woo	Jason E Fish	Stephanie Woo	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. jason.fish@utoronto.ca	Canadian Institutes of Health Research; 
Qian L, Van Laake LW, Huang Y, Liu S, Wendland MF, Srivastava D	miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes.	J. Exp. Med.	208:3:549-60	2011	21383058		Li Qian, Linda W Van Laake, Yu Huang, Siyuan Liu, Michael F Wendland, Deepak Srivastava	Li Qian	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA 94143, USA.	NHLBI NIH HHS; U01 HL100406
Li Q, Kannan A, DeMayo FJ, Lydon JP, Cooke PS, Yamagishi H, Srivastava D, Bagchi MK, Bagchi IC	The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2.	Science	331:6019:912-6	2011	21330545		Quanxi Li, Athilakshmi Kannan, Francesco J DeMayo, John P Lydon, Paul S Cooke, Hiroyuki Yamagishi, Deepak Srivastava, Milan K Bagchi, Indrani C Bagchi	Quanxi Li	Indrani C Bagchi	Department of Comparative Biosciences, University of Illinois Urbana/Champaign, Urbana, IL 61820, USA.	NICHD NIH HHS; U54HD055787
Yu S, Crawford D, Tsuchihashi T, Behrens TW, Srivastava D	The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling.	Dev. Dyn.	240:2:384-93	2011	21246655		Sangho Yu, Dianna Crawford, Takatoshi Tsuchihashi, Timothy W Behrens, Deepak Srivastava	Sangho Yu	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NHLBI NIH HHS; R01 HL080592-06
Tsuchihashi T, Maeda J, Shin CH, Ivey KN, Black BL, Olson EN, Yamagishi H, Srivastava D	Hand2 function in second heart field progenitors is essential for cardiogenesis.	Dev. Biol.	351:1:62-9	2011	21185281		Takatoshi Tsuchihashi, Jun Maeda, Chong H Shin, Kathryn N Ivey, Brian L Black, Eric N Olson, Hiroyuki Yamagishi, Deepak Srivastava	Takatoshi Tsuchihashi	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; U01 HL100401
Sheehy NT, Cordes KR, White MP, Ivey KN, Srivastava D	The neural crest-enriched microRNA miR-452 regulates epithelial-mesenchymal signaling in the first pharyngeal arch.	Development	137:24:4307-16	2010	21098571		Neil T Sheehy, Kimberly R Cordes, Mark P White, Kathryn N Ivey, Deepak Srivastava	Neil T Sheehy	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NCRR NIH HHS; C06 RR018928
Park CY, Pierce SA, von Drehle M, Ivey KN, Morgan JA, Blau HM, Srivastava D	skNAC, a Smyd1-interacting transcription factor, is involved in cardiac development and skeletal muscle growth and regeneration.	Proc. Natl. Acad. Sci. U.S.A.	107:48:20750-5	2010	21071677		Chong Yon Park, Stephanie A Pierce, Morgan von Drehle, Kathryn N Ivey, Jayson A Morgan, Helen M Blau, Deepak Srivastava	Chong Yon Park	Deepak Srivastava	Department of Pediatrics, Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA.	NHLBI NIH HHS; U01 HL100397
Maitra M, Koenig SN, Srivastava D, Garg V	Identification of GATA6 sequence variants in patients with congenital heart defects.	Pediatr. Res.	68:4:281-5	2010	20581743		Meenakshi Maitra, Sara N Koenig, Deepak Srivastava, Vidu Garg	Meenakshi Maitra	Vidu Garg	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.	NHLBI NIH HHS; R01HL088965
Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D	Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.	Cell	142:3:375-86	2010	20691899		Masaki Ieda, Ji-Dong Fu, Paul Delgado-Olguin, Vasanth Vedantham, Yohei Hayashi, Benoit G Bruneau, Deepak Srivastava	Masaki Ieda	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA 94158, USA. ieda@cpnet.med.keio.ac.jp	NHLBI NIH HHS; U01 HL100406-03
Ivey KN, Srivastava D	MicroRNAs as regulators of differentiation and cell fate decisions.	Cell Stem Cell	7:1:36-41	2010	20621048		Kathryn N Ivey, Deepak Srivastava	Kathryn N Ivey	Deepak Srivastava	Department of Pediatrics, Gladstone Institute of Cardiovascular Disease, University of California San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Nigam V, Sievers HH, Jensen BC, Sier HA, Simpson PC, Srivastava D, Mohamed SA	Altered microRNAs in bicuspid aortic valve: a comparison between stenotic and insufficient valves.	J. Heart Valve Dis.	19:4:459-65	2010	20845893		Vishal Nigam, Hans H Sievers, Brian C Jensen, Holger A Sier, Paul C Simpson, Deepak Srivastava, Salah A Mohamed	Vishal Nigam	Salah A Mohamed	Department of Pediatrics (Cardiology), University of California, San Francisco, USA.	NHLBI NIH HHS; K08 HL096836
van Laake LW, Qian L, Cheng P, Huang Y, Hsiao EC, Conklin BR, Srivastava D	Reporter-based isolation of induced pluripotent stem cell- and embryonic stem cell-derived cardiac progenitors reveals limited gene expression variance.	Circ. Res.	107:3:340-7	2010	20558827		Linda W van Laake, Li Qian, Paul Cheng, Yu Huang, Edward C Hsiao, Bruce R Conklin, Deepak Srivastava	Linda W van Laake	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 94158, USA.	NHLBI NIH HHS; U01 HL100406
Shrivastava S, Srivastava D, Olson EN, DiMaio JM, Bock-Marquette I	Thymosin beta4 and cardiac repair.	Ann. N. Y. Acad. Sci.	1194:87-96	2010	20536454		Santwana Shrivastava, Deepak Srivastava, Eric N Olson, J Michael DiMaio, Ildiko Bock-Marquette	Santwana Shrivastava	Ildiko Bock-Marquette	Department of Cardiovascular and Thoracic Surgery, University of Texas, Southwestern Medical Center, Dallas, Texas, USA.	NA
Qian L, Srivastava D	Monkeying around with cardiac progenitors: hope for the future.	J. Clin. Invest.	120:4:1034-6	2010	20335651		Li Qian, Deepak Srivastava	Li Qian	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, Department of Pediatrics, University of California, San Francisco, California 94158, USA.	NHLBI NIH HHS; U01 HL100406
Cordes KR, Srivastava D, Ivey KN	MicroRNAs in cardiac development.	Pediatr Cardiol	31:3:349-56	2010	20140609		Kimberly R Cordes, Deepak Srivastava, Kathryn N Ivey	Kimberly R Cordes	Kathryn N Ivey	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, San Francisco, CA 94158, USA.	NA
Fish JE, Yan MS, Matouk CC, St Bernard R, Ho JJ, Ho JJ, Gavryushova A, Srivastava D, Marsden PA	Hypoxic repression of endothelial nitric-oxide synthase transcription is coupled with eviction of promoter histones.	J. Biol. Chem.	285:2:810-26	2010	19880524		Jason E Fish, Matthew S Yan, Charles C Matouk, Rosanne St Bernard, J J David Ho, J J David Ho, Anna Gavryushova, Deepak Srivastava, Philip A Marsden	Jason E Fish	Philip A Marsden	Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.	Canadian Institutes of Health Research; MOP 79475
Woolfrey KM, Srivastava DP, Photowala H, Yamashita M, Barbolina MV, Cahill ME, Xie Z, Jones KA, Quilliam LA, Prakriya M, Penzes P	Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines.	Nat. Neurosci.	12:10:1275-84	2009	19734897		Kevin M Woolfrey, Deepak P Srivastava, Huzefa Photowala, Megumi Yamashita, Maria V Barbolina, Michael E Cahill, Zhong Xie, Kelly A Jones, Lawrence A Quilliam, Murali Prakriya, Peter Penzes	Kevin M Woolfrey	Peter Penzes	Department of Physiology and Biological Chemistry, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.	NINDS NIH HHS; R01 NS057499-02
Nigam V, Srivastava D	Notch1 represses osteogenic pathways in aortic valve cells.	J. Mol. Cell. Cardiol.	47:6:828-34	2009	19695258		Vishal Nigam, Deepak Srivastava	Vishal Nigam	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Departments of Pediatrics, University of California, San Francisco, CA 94158, USA. vnigam@ucsd.edu	NICHD NIH HHS; T32 HD049303
Kwon C, Qian L, Cheng P, Nigam V, Arnold J, Srivastava D	A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate.	Nat. Cell Biol.	11:8:951-7	2009	19620969		Chulan Kwon, Li Qian, Paul Cheng, Vishal Nigam, Joshua Arnold, Deepak Srivastava	Chulan Kwon	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Departments of Pediatrics and Biochemistry & Biophysics, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. ckwon@gladstone.ucsf.edu	NHLBI NIH HHS; U01 HL100406
Shieh JT, Srivastava D	Heart malformation: what are the chances it could happen again?	Circulation	120:4:269-71	2009	19597046		Joseph T C Shieh, Deepak Srivastava	Joseph T C Shieh	Deepak Srivastava		NHLBI NIH HHS; K08 HL092970-01A1
Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D	miR-145 and miR-143 regulate smooth muscle cell fate and plasticity.	Nature	460:7256:705-10	2009	19578358		Kimberly R Cordes, Neil T Sheehy, Mark P White, Emily C Berry, Sarah U Morton, Alecia N Muth, Ting-Hein Lee, Joseph M Miano, Kathryn N Ivey, Deepak Srivastava	Kimberly R Cordes	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; U01 HL100406
Bock-Marquette I, Shrivastava S, Pipes GC, Thatcher JE, Blystone A, Shelton JM, Galindo CL, Melegh B, Srivastava D, Olson EN, DiMaio JM	Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo.	J. Mol. Cell. Cardiol.	46:5:728-38	2009	19358334		Ildiko Bock-Marquette, Santwana Shrivastava, G C Teg Pipes, Jeffrey E Thatcher, Allissa Blystone, John M Shelton, Cristi L Galindo, Bela Melegh, Deepak Srivastava, Eric N Olson, J Michael DiMaio	Ildiko Bock-Marquette	J Michael DiMaio	Department of Cardiovascular and Thoracic Surgery, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, TX 75390-9148, USA. Ildiko.Bock-Marquette@UTSouthwestern.edu	NICHD NIH HHS; K08 HD054872-02
Cordes KR, Srivastava D	MicroRNA regulation of cardiovascular development.	Circ. Res.	104:6:724-32	2009	19325160		Kimberly R Cordes, Deepak Srivastava	Kimberly R Cordes	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL080592-06
Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL	Alternative induced pluripotent stem cell characterization criteria for in vitro applications.	Cell Stem Cell	4:3:198-9; author reply 202	2009	19265656		James Ellis, Benoit G Bruneau, Gordon Keller, Ihor R Lemischka, Andras Nagy, Janet Rossant, Deepak Srivastava, Peter W Zandstra, William L Stanford	James Ellis	William L Stanford	ntario Human IPS Cell Facility, SickKids Research Institute, University of Toronto, Toronto, Ontario M5G 1L7, Canada.	NA
Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D	Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling.	Dev. Cell	16:2:233-44	2009	19217425		Masaki Ieda, Takatoshi Tsuchihashi, Kathryn N Ivey, Robert S Ross, Ting-Ting Hong, Robin M Shaw, Deepak Srivastava	Masaki Ieda	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 94158, USA.	NHLBI NIH HHS; R01 HL094414-04
Fish JE, Srivastava D	MicroRNAs: opening a new vein in angiogenesis research.	Sci Signal	2:52:pe1	2009	19126861		Jason E Fish, Deepak Srivastava	Jason E Fish	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL080592-06
Kwon C, Cordes KR, Srivastava D	Wnt/beta-catenin signaling acts at multiple developmental stages to promote mammalian cardiogenesis.	Cell Cycle	7:24:3815-8	2008	19066459		Chulan Kwon, Kimberly R Cordes, Deepak Srivastava	Chulan Kwon	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, San Francisco, California 94158, USA. ckwon@gladstone.ucsf.edu	NHLBI NIH HHS; R01 HL080592-06
Maitra M, Schluterman MK, Nichols HA, Richardson JA, Lo CW, Srivastava D, Garg V	Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development.	Dev. Biol.	326:2:368-77	2009	19084512		Meenakshi Maitra, Marie K Schluterman, Haley A Nichols, James A Richardson, Cecilia W Lo, Deepak Srivastava, Vidu Garg	Meenakshi Maitra	Vidu Garg	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.	NHLBI NIH HHS; R01 HL088965-02
Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ	Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart.	Proc. Natl. Acad. Sci. U.S.A.	105:46:17824-9	2008	19004760		Zhiyv Niu, Dinakar Iyer, Simon J Conway, James F Martin, Kathryn Ivey, Deepak Srivastava, Alfred Nordheim, Robert J Schwartz	Zhiyv Niu	Robert J Schwartz	Center for Cardiovascular Development, Section of Cardiovascular Sciences, Baylor College of Medicine, Houston, TX 77030, USA.	NHLBI NIH HHS; R01 HL092508-01A1
Morton SU, Scherz PJ, Cordes KR, Ivey KN, Stainier DY, Srivastava D	microRNA-138 modulates cardiac patterning during embryonic development.	Proc. Natl. Acad. Sci. U.S.A.	105:46:17830-5	2008	19004786		Sarah U Morton, Paul J Scherz, Kimberly R Cordes, Kathryn N Ivey, Didier Y R Stainier, Deepak Srivastava	Sarah U Morton	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, Department of Pediatrics, University of California, San Francisco, CA 94158, USA.	NHLBI NIH HHS; HL-54737
Ransom JF, King IN, Garg V, Srivastava D	A rare human sequence variant reveals myocardin autoinhibition.	J. Biol. Chem.	283:51:35845-52	2008	18852265		Joshua F Ransom, Isabelle N King, Vidu Garg, Deepak Srivastava	Joshua F Ransom	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL080592
Fish JE, Santoro MM, Morton SU, Yu S, Yeh RF, Wythe JD, Ivey KN, Bruneau BG, Stainier DY, Srivastava D	miR-126 regulates angiogenic signaling and vascular integrity.	Dev. Cell	15:2:272-84	2008	18694566		Jason E Fish, Massimo M Santoro, Sarah U Morton, Sangho Yu, Ru-Fang Yeh, Joshua D Wythe, Kathryn N Ivey, Benoit G Bruneau, Didier Y R Stainier, Deepak Srivastava	Jason E Fish	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL080592-05
Ivey KN, Sutcliffe D, Richardson J, Clyman RI, Garcia JA, Srivastava D	Transcriptional regulation during development of the ductus arteriosus.	Circ. Res.	103:4:388-95	2008	18635823		Kathryn N Ivey, David Sutcliffe, James Richardson, Ronald I Clyman, Joseph A Garcia, Deepak Srivastava	Kathryn N Ivey	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, USA.	NHLBI NIH HHS; R01 HL080592-05
Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D	Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction.	Circulation	117:17:2224-31	2008	18427137		Ankur Saxena, Jason E Fish, Michael D White, Sangho Yu, James W P Smyth, Robin M Shaw, J Michael DiMaio, Deepak Srivastava	Ankur Saxena	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL080592-05
Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D	MicroRNA regulation of cell lineages in mouse and human embryonic stem cells.	Cell Stem Cell	2:3:219-29	2008	18371447		Kathryn N Ivey, Alecia Muth, Joshua Arnold, Frank W King, Ru-Fang Yeh, Jason E Fish, Edward C Hsiao, Robert J Schwartz, Bruce R Conklin, Harold S Bernstein, Deepak Srivastava	Kathryn N Ivey	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL057181-13
Gong B, Sun J, Vargas G, Chang Q, Xu Y, Srivastava D, Boor PJ	Nonlinear imaging study of extracellular matrix in chemical-induced, developmental dissecting aortic aneurysm: evidence for defective collagen type III.	Birth Defects Res. Part A Clin. Mol. Teratol.	82:1:16-24	2008	18044709		Bin Gong, Ju Sun, Grace Vargas, Qing Chang, Ya Xu, Deepak Srivastava, Paul J Boor	Bin Gong	Paul J Boor	Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA.	NIEHS NIH HHS; 1 R21 ES013038-01
Jia H, King IN, Chopra SS, Wan H, Ni TT, Jiang C, Guan X, Wells S, Srivastava D, Zhong TP	Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5.	Proc. Natl. Acad. Sci. U.S.A.	104:35:14008-13	2007	17715064		Haibo Jia, Isabelle N King, Sameer S Chopra, Haiyan Wan, Terri T Ni, Charlie Jiang, Xiaoqun Guan, Sam Wells, Deepak Srivastava, Tao P Zhong	Haibo Jia	Tao P Zhong	Department of Medicine and Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.	NHLBI NIH HHS; R01 HL073348-02
Srivastava D, Saxena A, Michael Dimaio J, Bock-Marquette I	Thymosin beta4 is cardioprotective after myocardial infarction.	Ann. N. Y. Acad. Sci.	1112:161-70	2007	17600280		Deepak Srivastava, Ankur Saxena, J Michael Dimaio, Ildiko Bock-Marquette	Deepak Srivastava	Ildiko Bock-Marquette	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA. dsrivastava@gladstone.ucsf.edu	NA
Rajagopal SK, Ma Q, Obler D, Shen J, Manichaikul A, Tomita-Mitchell A, Boardman K, Briggs C, Garg V, Srivastava D, Goldmuntz E, Broman KW, Benson DW, Smoot LB, Pu WT	Spectrum of heart disease associated with murine and human GATA4 mutation.	J. Mol. Cell. Cardiol.	43:6:677-85	2007	17643447		Satish K Rajagopal, Qing Ma, Dita Obler, Jie Shen, Ani Manichaikul, Aoy Tomita-Mitchell, Kari Boardman, Christine Briggs, Vidu Garg, Deepak Srivastava, Elizabeth Goldmuntz, Karl W Broman, D Woodrow Benson, Leslie B Smoot, William T Pu	Satish K Rajagopal	William T Pu	Department of Cardiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.	NHLBI NIH HHS; T32 HL 007572
Kwon C, Arnold J, Hsiao EC, Taketo MM, Conklin BR, Srivastava D	Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors.	Proc. Natl. Acad. Sci. U.S.A.	104:26:10894-9	2007	17576928		Chulan Kwon, Joshua Arnold, Edward C Hsiao, Makoto M Taketo, Bruce R Conklin, Deepak Srivastava	Chulan Kwon	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, 1650 Owens Street, San Francisco, CA 94158, USA.	NCRR NIH HHS; C06 RR018928
Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL	Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics.	Circulation	115:23:3015-38	2007	17519398		Mary Ella Pierpont, Craig T Basson, D Woodrow Benson, Bruce D Gelb, Therese M Giglia, Elizabeth Goldmuntz, Glenn McGee, Craig A Sable, Deepak Srivastava, Catherine L Webb	Mary Ella Pierpont	Catherine L Webb	Children's Hospital of Minnesota and University of Minnesota, USA.	NA
Xin M, Small EM, van Rooij E, Qi X, Richardson JA, Srivastava D, Nakagawa O, Olson EN	Essential roles of the bHLH transcription factor Hrt2 in repression of atrial gene expression and maintenance of postnatal cardiac function.	Proc. Natl. Acad. Sci. U.S.A.	104:19:7975-80	2007	17468400		Mei Xin, Eric M Small, Eva van Rooij, Xiaoxia Qi, James A Richardson, Deepak Srivastava, Osamu Nakagawa, Eric N Olson	Mei Xin	Eric N Olson	Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390, USA.	NA
Schluterman MK, Krysiak AE, Kathiriya IS, Abate N, Chandalia M, Srivastava D, Garg V	Screening and biochemical analysis of GATA4 sequence variations identified in patients with congenital heart disease.	Am. J. Med. Genet. A	143A:8:817-23	2007	17352393		Marie K Schluterman, Amanda E Krysiak, Irfan S Kathiriya, Nicola Abate, Manisha Chandalia, Deepak Srivastava, Vidu Garg	Marie K Schluterman	Vidu Garg	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA.	NA
Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D	Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.	Cell	129:2:303-17	2007	17397913		Yong Zhao, Joshua F Ransom, Ankang Li, Vasanth Vedantham, Morgan von Drehle, Alecia N Muth, Takatoshi Tsuchihashi, Michael T McManus, Robert J Schwartz, Deepak Srivastava	Yong Zhao	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; T32HL007731
Zhao Y, Srivastava D	A developmental view of microRNA function.	Trends Biochem. Sci.	32:4:189-97	2007	17350266		Yong Zhao, Deepak Srivastava	Yong Zhao	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Ransom J, Srivastava D	The genetics of cardiac birth defects.	Semin. Cell Dev. Biol.	18:1:132-9	2007	17240175		Joshua Ransom, Deepak Srivastava	Joshua Ransom	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and the Department of Pediatrics, University of California at San Francisco, 1650 Owens Street, San Francisco, CA 94158, United States.	NA
Ivey KN, Srivastava D	The paradoxical patent ductus arteriosus.	J. Clin. Invest.	116:11:2863-5	2006	17080192		Kathryn N Ivey, Deepak Srivastava	Kathryn N Ivey	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, University of California San Francisco, San Francisco, California 94158, USA.	NA
Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK	Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition.	Circulation	114:17:1838-46	2006	17030682		Kota V Ramana, Monte S Willis, Michael D White, Jureta W Horton, J Michael DiMaio, Deepak Srivastava, Aruni Bhatnagar, Satish K Srivastava	Kota V Ramana	Satish K Srivastava	Department of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX 77555, USA.	NIGMS NIH HHS; GM71036
Srivastava D	Making or breaking the heart: from lineage determination to morphogenesis.	Cell	126:6:1037-48	2006	16990131		Deepak Srivastava	Deepak Srivastava	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics and Biochemistry, University of California, San Francisco, CA 94158, USA. dsrivastava@gladstone.ucsf.edu	NA
Srivastava D, Yu S	Stretching to meet needs: integrin-linked kinase and the cardiac pump.	Genes Dev.	20:17:2327-31	2006	16951248		Deepak Srivastava, Sangho Yu	Deepak Srivastava	Sangho Yu	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California at San Francisco, San Francisco, California 94158, USA. dsrivastava@galdstone.ucsf.edu	NA
Srivastava D, Ivey KN	Potential of stem-cell-based therapies for heart disease.	Nature	441:7097:1097-9	2006	16810246		Deepak Srivastava, Kathryn N Ivey	Deepak Srivastava	Kathryn N Ivey	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California San Francisco, 1650 Owens Street, San Francisco, California 94158, USA. dsrivastava@Gladstone.ucsf.edu	NA
Capellini TD, Di Giacomo G, Salsi V, Brendolan A, Ferretti E, Srivastava D, Zappavigna V, Selleri L	Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression.	Development	133:11:2263-73	2006	16672333		Terence D Capellini, Giuseppina Di Giacomo, Valentina Salsi, Andrea Brendolan, Elisabetta Ferretti, Deepak Srivastava, Vincenzo Zappavigna, Licia Selleri	Terence D Capellini	Licia Selleri	Department of Cell and Developmental Biology, Cornell University Weill Medical School, New York, NY 10021, USA.	NICHD NIH HHS; HD43997
King IN, Kathiriya IS, Murakami M, Nakagawa M, Gardner KA, Srivastava D, Nakagawa O	Hrt and Hes negatively regulate Notch signaling through interactions with RBP-Jkappa.	Biochem. Biophys. Res. Commun.	345:1:446-52	2006	16682003		Isabelle N King, Irfan S Kathiriya, Masao Murakami, Masayo Nakagawa, Kelly A Gardner, Deepak Srivastava, Osamu Nakagawa	Isabelle N King	Osamu Nakagawa	Department of Pediatrics, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9063, USA. iking@gladstone.ucsf.edu	NHLBI NIH HHS; K08 HL079260-02
Maeda J, Yamagishi H, McAnally J, Yamagishi C, Srivastava D	Tbx1 is regulated by forkhead proteins in the secondary heart field.	Dev. Dyn.	235:3:701-10	2006	16444712		Jun Maeda, Hiroyuki Yamagishi, John McAnally, Chihiro Yamagishi, Deepak Srivastava	Jun Maeda	Deepak Srivastava	Department of Pediatrics, Division of Pediatric Cardiology, Keio University School of Medicine, Tokyo, Japan.	NHLBI NIH HHS; U01 HL100406-04
Yamagishi C, Yamagishi H, Maeda J, Tsuchihashi T, Ivey K, Hu T, Srivastava D	Sonic hedgehog is essential for first pharyngeal arch development.	Pediatr. Res.	59:3:349-54	2006	16492970		Chihiro Yamagishi, Hiroyuki Yamagishi, Jun Maeda, Takatoshi Tsuchihashi, Kathryn Ivey, Tonghuan Hu, Deepak Srivastava	Chihiro Yamagishi	Deepak Srivastava	Department of Pediatrics, Keio University School of Medicine, Tokyo, Japan.	NA
Gong B, Trent MB, Srivastava D, Boor PJ	Chemical-induced, nonlethal, developmental model of dissecting aortic aneurysm.	Birth Defects Res. Part A Clin. Mol. Teratol.	76:1:29-38	2006	16397885		Bin Gong, Margaret B Trent, Deepak Srivastava, Paul J Boor	Bin Gong	Paul J Boor	Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555, USA.	NIEHS NIH HHS; 1 R21 ES013038-01
Srivastava D	Genetic regulation of cardiogenesis and congenital heart disease.	Annu Rev Pathol	1:199-213	2006	18039113		Deepak Srivastava	Deepak Srivastava	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease, Department of Pediatrics, University of California, San Francisco, California 94158, USA. dsrivastava@gladstone.ucsf.edu	NA
Koshiba-Takeuchi K, Takeuchi JK, Arruda EP, Kathiriya IS, Mo R, Hui CC, Srivastava D, Bruneau BG	Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.	Nat. Genet.	38:2:175-83	2006	16380715		Kazuko Koshiba-Takeuchi, Jun K Takeuchi, Eric P Arruda, Irfan S Kathiriya, Rong Mo, Chi-chung Hui, Deepak Srivastava, Benoit G Bruneau	Kazuko Koshiba-Takeuchi	Benoit G Bruneau	Programs in Cardiovascular Research, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.	NA
Kwon C, Han Z, Olson EN, Srivastava D	MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling.	Proc. Natl. Acad. Sci. U.S.A.	102:52:18986-91	2005	16357195		Chulan Kwon, Zhe Han, Eric N Olson, Deepak Srivastava	Chulan Kwon	Deepak Srivastava	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, 1650 Owens Street, San Francisco, CA 94158.	NA
Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG	The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.	Cell	123:2:347-58	2005	16239150		Danny L Costantini, Eric P Arruda, Pooja Agarwal, Kyoung-Han Kim, Yonghong Zhu, Wei Zhu, Melanie Lebel, Chi Wa Cheng, Chong Y Park, Stephanie A Pierce, Alejandra Guerchicoff, Guido D Pollevick, Toby Y Chan, M Golam Kabir, Shuk Han Cheng, Mansoor Husain, Charles Antzelevitch, Deepak Srivastava, Gil J Gross, Chi-chung Hui, Peter H Backx, Benoit G Bruneau	Danny L Costantini	Benoit G Bruneau	Program in Cardiovascular Research, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.	NHLBI NIH HHS; R01 HL047678-13
Garg V, Muth AN, Ransom JF, Schluterman MK, Barnes R, King IN, Grossfeld PD, Srivastava D	Mutations in NOTCH1 cause aortic valve disease.	Nature	437:7056:270-4	2005	16025100		Vidu Garg, Alecia N Muth, Joshua F Ransom, Marie K Schluterman, Robert Barnes, Isabelle N King, Paul D Grossfeld, Deepak Srivastava	Vidu Garg	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA. vidu.garg@utsouthwestern.edu	NHLBI NIH HHS; K08 HL079260-01
Zhao Y, Samal E, Srivastava D	Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis.	Nature	436:7048:214-20	2005	15951802		Yong Zhao, Eva Samal, Deepak Srivastava	Yong Zhao	Deepak Srivastava	Department of Pediatrics (Cardiology), University of Texas Southwestern Medical Center and Children's Medical Center Dallas, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.	NA
Aiyer AR, Honarpour N, Herz J, Srivastava D	Loss of Apaf-1 leads to partial rescue of the HAND2-null phenotype.	Dev. Biol.	278:1:155-62	2005	15649468		Aparna R Aiyer, Narimon Honarpour, Joachim Herz, Deepak Srivastava	Aparna R Aiyer	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Room NA8.124, Dallas, TX 75390-9148, USA.	NA
McFadden DG, Barbosa AC, Richardson JA, Schneider MD, Srivastava D, Olson EN	The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner.	Development	132:1:189-201	2005	15576406		David G McFadden, Ana C Barbosa, James A Richardson, Michael D Schneider, Deepak Srivastava, Eric N Olson	David G McFadden	Eric N Olson	Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390-9148, USA.	NA
Bock-Marquette I, Saxena A, White MD, Dimaio JM, Srivastava D	Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair.	Nature	432:7016:466-72	2004	15565145		Ildiko Bock-Marquette, Ankur Saxena, Michael D White, J Michael Dimaio, Deepak Srivastava	Ildiko Bock-Marquette	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd, Dallas, Texas 75390-9148, USA.	NA
Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O	Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism.	J. Biol. Chem.	279:52:54937-43	2004	15485867		Irfan S Kathiriya, Isabelle N King, Masao Murakami, Masayo Nakagawa, John M Astle, Kelly A Gardner, Robert D Gerard, Eric N Olson, Deepak Srivastava, Osamu Nakagawa	Irfan S Kathiriya	Osamu Nakagawa	Department of Molecular Biology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA.	NHLBI NIH HHS; L40 HL078465-02
Hu T, Yamagishi H, Maeda J, McAnally J, Yamagishi C, Srivastava D	Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors.	Development	131:21:5491-502	2004	15469978		Tonghuan Hu, Hiroyuki Yamagishi, Jun Maeda, John McAnally, Chihiro Yamagishi, Deepak Srivastava	Tonghuan Hu	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390-9148, USA.	NA
Cowan CA, Yokoyama N, Saxena A, Chumley MJ, Silvany RE, Baker LA, Srivastava D, Henkemeyer M	Ephrin-B2 reverse signaling is required for axon pathfinding and cardiac valve formation but not early vascular development.	Dev. Biol.	271:2:263-71	2004	15223333		Chad A Cowan, Nobuhiko Yokoyama, Ankur Saxena, Michael J Chumley, Robert E Silvany, Linda A Baker, Deepak Srivastava, Mark Henkemeyer	Chad A Cowan	Mark Henkemeyer	Center for Developmental Biology and Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.	NIMH NIH HHS; R01-MH66332
Srivastava D	Heart disease: an ongoing genetic battle?	Nature	429:6994:819-22	2004	15215849		Deepak Srivastava	Deepak Srivastava	Deepak Srivastava		NA
Yamagishi H, Srivastava D	Unraveling the genetic and developmental mysteries of 22q11 deletion syndrome.	Trends Mol Med	9:9:383-9	2003	13129704		Hiroyuki Yamagishi, Deepak Srivastava	Hiroyuki Yamagishi	Deepak Srivastava	Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi, Shinjyuku-ku, Tokyo 160-8582, Japan. hyamag@sc.itc.keio.ac.jp	NA
Garg V, Kathiriya IS, Barnes R, Schluterman MK, King IN, Butler CA, Rothrock CR, Eapen RS, Hirayama-Yamada K, Joo K, Matsuoka R, Cohen JC, Srivastava D	GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5.	Nature	424:6947:443-7	2003	12845333		Vidu Garg, Irfan S Kathiriya, Robert Barnes, Marie K Schluterman, Isabelle N King, Cheryl A Butler, Caryn R Rothrock, Reenu S Eapen, Kayoko Hirayama-Yamada, Kunitaka Joo, Rumiko Matsuoka, Jonathan C Cohen, Deepak Srivastava	Vidu Garg	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Rm. NA8.124, Dallas, Texas 75390-9148, USA. Vidu.Garg@UTSouthwestern.edu	NHLBI NIH HHS; L40 HL078465-02
Ivey K, Tyson B, Ukidwe P, McFadden DG, Levi G, Olson EN, Srivastava D, Wilkie TM	Galphaq and Galpha11 proteins mediate endothelin-1 signaling in neural crest-derived pharyngeal arch mesenchyme.	Dev. Biol.	255:2:230-7	2003	12648486		Kathryn Ivey, Brandi Tyson, Pallavi Ukidwe, David G McFadden, Giovanni Levi, Eric N Olson, Deepak Srivastava, Thomas M Wilkie	Kathryn Ivey	Thomas M Wilkie	Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, , Dallas, TX 75390-9104, USA.	NA
Yamagishi C, Hierck BP, Gittenberger-De Groot AC, Yamagishi H, Srivastava D	Functional attenuation of UFD1l, a 22q11.2 deletion syndrome candidate gene, leads to cardiac outflow septation defects in chicken embryos.	Pediatr. Res.	53:4:546-53	2003	12612215		Chihiro Yamagishi, Beerend P Hierck, Adriana C Gittenberger-De Groot, Hiroyuki Yamagishi, Deepak Srivastava	Chihiro Yamagishi	Deepak Srivastava	Department of Pediatrics, University of Texas, Southwestern Medical Center at Dallas, Dallas 75390-9148, USA.	NA
Yamagishi H, Maeda J, Hu T, McAnally J, Conway SJ, Kume T, Meyers EN, Yamagishi C, Srivastava D	Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer.	Genes Dev.	17:2:269-81	2003	12533514		Hiroyuki Yamagishi, Jun Maeda, Tonghuan Hu, John McAnally, Simon J Conway, Tsutomu Kume, Erik N Meyers, Chihiro Yamagishi, Deepak Srivastava	Hiroyuki Yamagishi	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA. Hiroyuki.Yamagishi@UTSouthwestern.edu	NA
He F, Yang XP, Srivastava DK, Wilson SH	DNA polymerase beta gene expression: the promoter activator CREB-1 is upregulated in Chinese hamster ovary cells by DNA alkylating agent-induced stress.	Biol. Chem.	384:1:19-23	2003	12674496		Feng He, Xiao-Ping Yang, Deepak K Srivastava, Samuel H Wilson	Feng He	Samuel H Wilson	Sealy Center for Molecular Science, University of Texas Medical Branch, Galveston, TX 77555-1068, USA.	NIEHS NIH HHS; ES06492
Srivastava D	Building a heart: implications for congenital heart disease.	J Nucl Cardiol	10:1:63-70		12569333		Deepak Srivastava	Deepak Srivastava	Deepak Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Tex 75390-9148, USA. Deepak.Srivastava@utsouthwestern.edu	NA
Villanueva MP, Aiyer AR, Muller S, Pletcher MT, Liu X, Emanuel B, Srivastava D, Reeves RH	Genetic and comparative mapping of genes dysregulated in mouse hearts lacking the Hand2 transcription factor gene.	Genomics	80:6:593-600	2002	12504851		Melissa P Villanueva, Aparna R Aiyer, Shaine Muller, Mathew T Pletcher, Xiao Liu, Beverly Emanuel, Deepak Srivastava, Roger H Reeves	Melissa P Villanueva	Roger H Reeves	Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.	NICHD NIH HHS; HD26979
Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K	Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis.	Cell Tissue Res.	310:2:201-12	2002	12397375		Makoto Abe, Yoshihiro Tamamura, Hiroyuki Yamagishi, Takashi Maeda, Joji Kato, Makoto J Tabata, Deepak Srivastava, Satoshi Wakisaka, Kojiro Kurisu	Makoto Abe	Kojiro Kurisu	Department of Oral Anatomy and Developmental Biology, Osaka University Graduate School of Dentistry, 1-8, Yamadaoka, Suita, Osaka 565-0871, Japan. makoto@dent.osaka-u.ac.jp	NA
Gottlieb PD, Pierce SA, Sims RJ, Yamagishi H, Weihe EK, Harriss JV, Maika SD, Kuziel WA, King HL, Olson EN, Nakagawa O, Srivastava D	Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis.	Nat. Genet.	31:1:25-32	2002	11923873		Paul D Gottlieb, Stephanie A Pierce, Robert J Sims, Hiroyuki Yamagishi, Elizabeth K Weihe, June V Harriss, Shanna D Maika, William A Kuziel, Heather L King, Eric N Olson, Osamu Nakagawa, Deepak Srivastava	Paul D Gottlieb	Deepak Srivastava	Section of Molecular Genetics and Microbiology and Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA. gottlieb@uts.cc.utexas.edu	NA
Srivastava D, Gottlieb PD, Olson EN	Molecular mechanisms of ventricular hypoplasia.	Cold Spring Harb. Symp. Quant. Biol.	67:121-5	2002	12858532		D Srivastava, P D Gottlieb, E N Olson	D Srivastava	E N Olson	Departments of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA.	NA
Yamagishi H, Yamagishi C, Nakagawa O, Harvey RP, Olson EN, Srivastava D	The combinatorial activities of Nkx2.5 and dHAND are essential for cardiac ventricle formation.	Dev. Biol.	239:2:190-203	2001	11784028		H Yamagishi, C Yamagishi, O Nakagawa, R P Harvey, E N Olson, D Srivastava	H Yamagishi	D Srivastava	Department of Pediatrics, Division of Cardiology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.	NHLBI NIH HHS; 5-R01-HL57181-04
Kunte A, Ivey K, Yamagishi C, Garg V, Yamagishi H, Srivastava D	A common cis-acting sequence in the DiGeorge critical region regulates bi-directional transcription of UFD1L and CDC45L.	Mech. Dev.	108:1-2:81-92	2001	11578863		A Kunte, K Ivey, C Yamagishi, V Garg, H Yamagishi, D Srivastava	A Kunte	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Rm. NA8.124, Dallas, TX 75390-9148, USA.	NHLBI NIH HHS; R01HLDE62591-01
Natarajan A, Yamagishi H, Ahmad F, Li D, Roberts R, Matsuoka R, Hill S, Srivastava D	Human eHAND, but not dHAND, is down-regulated in cardiomyopathies.	J. Mol. Cell. Cardiol.	33:9:1607-14	2001	11549340		A Natarajan, H Yamagishi, F Ahmad, D Li, R Roberts, R Matsuoka, S Hill, D Srivastava	A Natarajan	D Srivastava	Division of Intensive Care, Department of Pediatrics, University of Texas Southwestern Medical Center, University of Texas Southwestern Medical Center, One Baylor Plaza, Dallas, Texas 75390-9148, USA.	NHLBI NIH HHS; 5-R01-HL57181-04
Garg V, Yamagishi C, Hu T, Kathiriya IS, Yamagishi H, Srivastava D	Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development.	Dev. Biol.	235:1:62-73	2001	11412027		V Garg, C Yamagishi, T Hu, I S Kathiriya, H Yamagishi, D Srivastava	V Garg	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Rm. NA8.124, Dallas, Texas 75390-9148, USA.	NHLBI NIH HHS; R01HLDE62591-01
Liu ZP, Nakagawa O, Nakagawa M, Yanagisawa H, Passier R, Richardson JA, Srivastava D, Olson EN	CHAMP, a novel cardiac-specific helicase regulated by MEF2C.	Dev. Biol.	234:2:497-509	2001	11397016		Z P Liu, O Nakagawa, M Nakagawa, H Yanagisawa, R Passier, J A Richardson, D Srivastava, E N Olson	Z P Liu	E N Olson	Department of Molecular Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.	NA
Srivastava D	Genetic assembly of the heart: implications for congenital heart disease.	Annu. Rev. Physiol.	63:451-69	2001	11181963		D Srivastava	D Srivastava	D Srivastava	Department of Pediatrics and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9148, USA. dsriva@mednet.swmed.edu	NA
Nakagawa O, McFadden DG, Nakagawa M, Yanagisawa H, Hu T, Srivastava D, Olson EN	Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling.	Proc. Natl. Acad. Sci. U.S.A.	97:25:13655-60	2000	11095750		O Nakagawa, D G McFadden, M Nakagawa, H Yanagisawa, T Hu, D Srivastava, E N Olson	O Nakagawa	E N Olson	Departments of Molecular Biology and Pediatrics, The University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, Texas 75390-9148, USA.	NA
McFadden DG, Charité J, Richardson JA, Srivastava D, Firulli AB, Olson EN	A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart.	Development	127:24:5331-41	2000	11076755		D G McFadden, J Charité, J A Richardson, D Srivastava, A B Firulli, E N Olson	D G McFadden	E N Olson	Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 75390-9148, USA.	NHLBI NIH HHS; R01 HL61677-01A1
Fisher SA, Langille BL, Srivastava D	Apoptosis during cardiovascular development.	Circ. Res.	87:10:856-64	2000	11073880		S A Fisher, B L Langille, D Srivastava	S A Fisher	D Srivastava	Departments of Medicine and Physiology, Case Western Reserve School of Medicine, Cleveland, Ohio, USA.	NA
Srivastava D, Olson EN	A genetic blueprint for cardiac development.	Nature	407:6801:221-6	2000	11001064		D Srivastava, E N Olson	D Srivastava	E N Olson	Department of Molecular Biology, University of Texas, Southwestern Medical Center at Dallas, 75390-9148, USA. dsriva@mednet.swmed.edu	NA
Angelo S, Lohr J, Lee KH, Ticho BS, Breitbart RE, Hill S, Yost HJ, Srivastava D	Conservation of sequence and expression of Xenopus and zebrafish dHAND during cardiac, branchial arch and lateral mesoderm development.	Mech. Dev.	95:1-2:231-7	2000	10906469		S Angelo, J Lohr, K H Lee, B S Ticho, R E Breitbart, S Hill, H J Yost, D Srivastava	S Angelo	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75235-9148, USA.	NHLBI NIH HHS; 5-R01 HL57181-04
Srivastava D	Congenital heart defects: trapping the genetic culprits.	Circ. Res.	86:9:917-8	2000	10807859		D Srivastava	D Srivastava	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texes, USA. dsriva@mednet.swmed.edu	NA
Fernandez-Teran M, Piedra ME, Kathiriya IS, Srivastava D, Rodriguez-Rey JC, Ros MA	Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway.	Development	127:10:2133-42	2000	10769237		M Fernandez-Teran, M E Piedra, I S Kathiriya, D Srivastava, J C Rodriguez-Rey, M A Ros	M Fernandez-Teran	M A Ros	Departamento de Anatomía y Biología Celular, Universidad de Cantabria, Spain.	NA
Yamagishi H, Olson EN, Srivastava D	The basic helix-loop-helix transcription factor, dHAND, is required for vascular development.	J. Clin. Invest.	105:3:261-70	2000	10675351		H Yamagishi, E N Olson, D Srivastava	H Yamagishi	D Srivastava	Department of Pediatrics, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA.	NHLBI NIH HHS; R01 HLDE62591-01
Srivastava D	DiGeorge syndrome: an enigma in mice and men.	Mol Med Today	6:1:13-4	2000	10637569		D Srivastava	D Srivastava	D Srivastava		NA
Kathiriya IS, Srivastava D	Left-right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease.	Am. J. Med. Genet.	97:4:271-9	2000	11376438		I S Kathiriya, D Srivastava	I S Kathiriya	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 75390-9148, USA.	NA
Nakagawa O, Nakagawa M, Richardson JA, Olson EN, Srivastava D	HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segments.	Dev. Biol.	216:1:72-84	1999	10588864		O Nakagawa, M Nakagawa, J A Richardson, E N Olson, D Srivastava	O Nakagawa	D Srivastava	Department of Molecular Biology, The University of Texas Southwestern Medical Center at Dallas, 6000 Harry Hines Boulevard, Dallas, Texas, 75235-9148, USA.	NHLBI NIH HHS; R01HLDE62591-01
	Reply: role of the dHAND-UFD1L pathway	Trends Genet.	15:7:253-4	1999	10390622			 Srivastava	 Yamagishi	Department of Pediatrics, Division of Cardiology and Department of Molecular Biology and Oncology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Room NA8.124, Dallas, TX 75235-9148, USA.	NA
Srivastava D	Developmental and genetic aspects of congenital heart disease.	Curr. Opin. Cardiol.	14:3:263-8	1999	10358798		D Srivastava	D Srivastava	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9148, USA. dsriva@mednet.swmed.edu	NA
Yamagishi H, Garg V, Matsuoka R, Thomas T, Srivastava D	A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects.	Science	283:5405:1158-61	1999	10024240		H Yamagishi, V Garg, R Matsuoka, T Thomas, D Srivastava	H Yamagishi	D Srivastava	Department of Pediatrics, Division of Cardiology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Room NA8.124, Dallas, TX 75235-9148, USA.	NHLBI NIH HHS; R01HL57181-01
Srivastava D	HAND proteins: molecular mediators of cardiac development and congenital heart disease.	Trends Cardiovasc. Med.	9:1-2:11-8		10189962		D Srivastava	D Srivastava	D Srivastava	Department of Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas 75235-9148, USA.	NA
Thomas T, Kurihara H, Yamagishi H, Kurihara Y, Yazaki Y, Olson EN, Srivastava D	A signaling cascade involving endothelin-1, dHAND and msx1 regulates development of neural-crest-derived branchial arch mesenchyme.	Development	125:16:3005-14	1998	9671575		T Thomas, H Kurihara, H Yamagishi, Y Kurihara, Y Yazaki, E N Olson, D Srivastava	T Thomas	D Srivastava	Department of Pediatrics, Division of Cardiology and Department of Molecular Biology and Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75235-9148, USA. edu.	NHLBI NIH HHS; R01HL57181-01
Thomas T, Yamagishi H, Overbeek PA, Olson EN, Srivastava D	The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness.	Dev. Biol.	196:2:228-36	1998	9576835		T Thomas, H Yamagishi, P A Overbeek, E N Olson, D Srivastava	T Thomas	D Srivastava	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9148, USA.	NHLBI NIH HHS; R01-HL57181-01
Firulli AB, McFadden DG, Lin Q, Srivastava D, Olson EN	Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1.	Nat. Genet.	18:3:266-70	1998	9500550		A B Firulli, D G McFadden, Q Lin, D Srivastava, E N Olson	A B Firulli	E N Olson	Department of Molecular Biology, The University of Texas Southwestern Medical Center at Dallas, 75235-9148, USA.	NHLBI NIH HHS; R01 HL061677-01A1
Srivastava D	Left, right ... which way to turn?	Nat. Genet.	17:3:252-4	1997	9354777		D Srivastava	D Srivastava	D Srivastava		NA
Srivastava D, Olson EN	Knowing in your heart what's right.	Trends Cell Biol.	7:11:447-53	1997	17709004		D Srivastava, E N Olson	D Srivastava	E N Olson		NA
Srivastava D, Thomas T, Lin Q, Kirby ML, Brown D, Olson EN	Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND.	Nat. Genet.	16:2:154-60	1997	9171826		D Srivastava, T Thomas, Q Lin, M L Kirby, D Brown, E N Olson	D Srivastava	E N Olson	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9148, USA. dsriva@mednet.swmed.edu	NHLBI NIH HHS; R01-HL57181-01
Lin Q, Srivastava D, Olson EN	A transcriptional pathway for cardiac development.	Cold Spring Harb. Symp. Quant. Biol.	62:405-11	1997	9598375		Q Lin, D Srivastava, E N Olson	Q Lin	E N Olson	Department of Molecular Biology and Oncology, University of Texas Southwestern Medical Center at Dallas 75235-9148, USA.	NA
Srivastava D, Olson EN	Neurotrophin-3 knocks heart off Trk.	Nat. Med.	2:10:1069-71	1996	8837596		D Srivastava, E N Olson	D Srivastava	E N Olson	Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas 75235-9148, USA.	NA
Olson EN, Srivastava D	Molecular pathways controlling heart development.	Science	272:5262:671-6	1996	8614825		E N Olson, D Srivastava	E N Olson	D Srivastava	Department of Molecular Biology and Oncology, University of Texas Southwestern Medical Center, Dallas, 75235-9148, USA.	NA
Srivastava D, Cserjesi P, Olson EN	A subclass of bHLH proteins required for cardiac morphogenesis.	Science	270:5244:1995-9	1995	8533092		D Srivastava, P Cserjesi, E N Olson	D Srivastava	E N Olson	Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.	NA
Srivastava D, Preminger T, Lock JE, Mandell V, Keane JF, Mayer JE, Kozakewich H, Spevak PJ	Hepatic venous blood and the development of pulmonary arteriovenous malformations in congenital heart disease.	Circulation	92:5:1217-22	1995	7648668		D Srivastava, T Preminger, J E Lock, V Mandell, J F Keane, J E Mayer, H Kozakewich, P J Spevak	D Srivastava	P J Spevak	Department of Cardiology, Children's Hospital, Harvard Medical School, Boston, Mass, USA.	NA
Srivastava D, Thompson EB	Two glucocorticoid binding sites on the human glucocorticoid receptor.	Endocrinology	127:4:1770-8	1990	2205477		D Srivastava, E B Thompson	D Srivastava	E B Thompson	Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston 77550.	NCI NIH HHS; CA-41407
Thompson EB, Srivastava D, Johnson BH	Interactions of the phenylpyrazolo steroid cortivazol with glucocorticoid receptors in steroid-sensitive and -resistant human leukemic cells.	Cancer Res.	49:8 Suppl:2253s-2258s	1989	2702665		E B Thompson, D Srivastava, B H Johnson	E B Thompson	B H Johnson	Department of Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston 77550.	NCI NIH HHS; CA41407
Chen W, Guo Y, Walker EJ, Shen F, Jun K, Oh SP, Degos V, Lawton MT, Tihan T, Davalos D, Akassoglou K, Nelson J, Pile-Spellman J, Su H, Young WL	Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain.	Arterioscler. Thromb. Vasc. Biol.	33:2:305-10	2013	23241407		Wanqiu Chen, Yi Guo, Espen J Walker, Fanxia Shen, Kristine Jun, S Paul Oh, Vincent Degos, Michael T Lawton, Tarik Tihan, Dimitrios Davalos, Katerina Akassoglou, Jeffrey Nelson, John Pile-Spellman, Hua Su, William L Young	Wanqiu Chen	William L Young	Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, CA 94110, USA	NIGMS NIH HHS; T32 GM008440
Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, Verdin E	Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor.	Science	339:6116:211-4	2013	23223453		Tadahiro Shimazu, Matthew D Hirschey, John Newman, Wenjuan He, Kotaro Shirakawa, Natacha Le Moan, Carrie A Grueter, Hyungwook Lim, Laura R Saunders, Robert D Stevens, Christopher B Newgard, Robert V Farese, Rafael de Cabo, Scott Ulrich, Katerina Akassoglou, Eric Verdin	Tadahiro Shimazu	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NA
Gut P, Baeza-Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, Akassoglou K, Verdin E, Hirschey MD, Stainier DY	Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism.	Nat. Chem. Biol.	9:2:97-104	2013	23201900		Philipp Gut, Bernat Baeza-Raja, Olov Andersson, Laura Hasenkamp, Joseph Hsiao, Daniel Hesselson, Katerina Akassoglou, Eric Verdin, Matthew D Hirschey, Didier Y R Stainier	Philipp Gut	Didier Y R Stainier	Department of Biochemistry and Biophysics, University of California-San Francisco, San Francisco, California, USA. philipp.gut@ucsf.edu	NIDDK NIH HHS; U01 DK089541
Kwan W, Träger U, Davalos D, Chou A, Bouchard J, Andre R, Miller A, Weiss A, Giorgini F, Cheah C, Möller T, Stella N, Akassoglou K, Tabrizi SJ, Muchowski PJ	Mutant huntingtin impairs immune cell migration in Huntington disease.	J. Clin. Invest.	122:12:4737-47	2012	23160193		Wanda Kwan, Ulrike Träger, Dimitrios Davalos, Austin Chou, Jill Bouchard, Ralph Andre, Aaron Miller, Andreas Weiss, Flaviano Giorgini, Christine Cheah, Thomas Möller, Nephi Stella, Katerina Akassoglou, Sarah J Tabrizi, Paul J Muchowski	Wanda Kwan	Paul J Muchowski	Biomedical Sciences Program, UCSF, San Francisco, California, USA.	NINDS NIH HHS; NS066361
Baeza-Raja B, Akassoglou K	Glucose homeostasis and p75NTR: the sweet side of neurotrophin receptor signaling.	Cell Cycle	11:17:3151-2	2012	22894898		Bernat Baeza-Raja, Katerina Akassoglou	Bernat Baeza-Raja	Katerina Akassoglou		NINDS NIH HHS; R01 NS051470
Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K	p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity.	Proc. Natl. Acad. Sci. U.S.A.	109:15:5838-43	2012	22460790		Bernat Baeza-Raja, Pingping Li, Natacha Le Moan, Benjamin D Sachs, Christian Schachtrup, Dimitrios Davalos, Eirini Vagena, Dave Bridges, Choel Kim, Alan R Saltiel, Jerrold M Olefsky, Katerina Akassoglou	Bernat Baeza-Raja	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94158, USA.	NICHD NIH HHS; U54 HD 012303-25
Le Moan N, Baeza-Raja B, Akassoglou K	p75 (NTR) and hypoxia: a breath of fresh air in neurotrophin receptor signaling.	Cell Cycle	11:5:829-30	2012	22333586		Natacha Le Moan, Bernat Baeza-Raja, Katerina Akassoglou	Natacha Le Moan	Katerina Akassoglou		NINDS NIH HHS; R01 NS051470
Pearn ML, Hu Y, Niesman IR, Patel HH, Drummond JC, Roth DM, Akassoglou K, Patel PM, Head BP	Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation.	Anesthesiology	116:2:352-61	2012	22198221		Matthew L Pearn, Yue Hu, Ingrid R Niesman, Hemal H Patel, John C Drummond, David M Roth, Katerina Akassoglou, Piyush M Patel, Brian P Head	Matthew L Pearn	Brian P Head	Department of Anesthesiology, University of California, San Diego, La Jolla, California, USA.	NINDS NIH HHS; R01NS051470
Davalos D, Akassoglou K	In vivo imaging of the mouse spinal cord using two-photon microscopy.	J Vis Exp	59:e2760	2012	22258623		Dimitrios Davalos, Katerina Akassoglou	Dimitrios Davalos	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, USA. ddavalos@gladstone.ucsf.edu	NINDS NIH HHS; NS066361
Davalos D, Ryu JK, Merlini M, Baeten KM, Le Moan N, Petersen MA, Deerinck TJ, Smirnoff DS, Bedard C, Hakozaki H, Gonias Murray S, Ling JB, Lassmann H, Degen JL, Ellisman MH, Akassoglou K	Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation.	Nat Commun	3:1227	2012	23187627		Dimitrios Davalos, Jae Kyu Ryu, Mario Merlini, Kim M Baeten, Natacha Le Moan, Mark A Petersen, Thomas J Deerinck, Dimitri S Smirnoff, Catherine Bedard, Hiroyuki Hakozaki, Sara Gonias Murray, Jennie B Ling, Hans Lassmann, Jay L Degen, Mark H Ellisman, Katerina Akassoglou	Dimitrios Davalos	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	Howard Hughes Medical Institute; 
Terrando N, Eriksson LI, Ryu JK, Yang T, Monaco C, Feldmann M, Jonsson Fagerlund M, Charo IF, Akassoglou K, Maze M	Resolving postoperative neuroinflammation and cognitive decline.	Ann. Neurol.	70:6:986-95	2011	22190370		Niccolò Terrando, Lars I Eriksson, Jae Kyu Ryu, Ting Yang, Claudia Monaco, Marc Feldmann, Malin Jonsson Fagerlund, Israel F Charo, Katerina Akassoglou, Mervyn Maze	Niccolò Terrando	Mervyn Maze	Department of Anesthesia and Perioperative Care, University of California at San Francisco, San Francisco, CA, USA.	NINDS NIH HHS; NS066361
Le Moan N, Houslay DM, Christian F, Houslay MD, Akassoglou K	Oxygen-dependent cleavage of the p75 neurotrophin receptor triggers stabilization of HIF-1α.	Mol. Cell	44:3:476-90	2011	22055192		Natacha Le Moan, Daniel M Houslay, Frank Christian, Miles D Houslay, Katerina Akassoglou	Natacha Le Moan	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928
Baeten KM, Akassoglou K	Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke.	Dev Neurobiol	71:11:1018-39	2011	21780303		Kim M Baeten, Katerina Akassoglou	Kim M Baeten	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NINDS NIH HHS; R01 NS066361
Davalos D, Akassoglou K	Fibrinogen as a key regulator of inflammation in disease.	Semin Immunopathol	34:1:43-62	2012	22037947		Dimitrios Davalos, Katerina Akassoglou	Dimitrios Davalos	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158, USA.	NINDS NIH HHS; R01 NS066361
Schachtrup C, Le Moan N, Passino MA, Akassoglou K	Hepatic stellate cells and astrocytes: Stars of scar formation and tissue repair.	Cell Cycle	10:11:1764-71	2011	21555919		Christian Schachtrup, Natacha Le Moan, Melissa A Passino, Katerina Akassoglou	Christian Schachtrup	Katerina Akassoglou	University of California at San Francisco, San Francisco, CA, USA.	NINDS NIH HHS; R01NS52189
Drew PJ, Shih AY, Driscoll JD, Knutsen PM, Blinder P, Davalos D, Akassoglou K, Tsai PS, Kleinfeld D	Chronic optical access through a polished and reinforced thinned skull.	Nat. Methods	7:12:981-4	2010	20966916		Patrick J Drew, Andy Y Shih, Jonathan D Driscoll, Per Magne Knutsen, Pablo Blinder, Dimitrios Davalos, Katerina Akassoglou, Philbert S Tsai, David Kleinfeld	Patrick J Drew	David Kleinfeld	Department of Physics, University of California at San Diego, San Diego, California, USA.	NCRR NIH HHS; RR021907
Schachtrup C, Ryu JK, Helmrick MJ, Vagena E, Galanakis DK, Degen JL, Margolis RU, Akassoglou K	Fibrinogen triggers astrocyte scar formation by promoting the availability of active TGF-beta after vascular damage.	J. Neurosci.	30:17:5843-54	2010	20427645		Christian Schachtrup, Jae K Ryu, Matthew J Helmrick, Eirini Vagena, Dennis K Galanakis, Jay L Degen, Richard U Margolis, Katerina Akassoglou	Christian Schachtrup	Katerina Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, California 94158, USA.	NINDS NIH HHS; R01NS052189
Ryu JK, Davalos D, Akassoglou K	Fibrinogen signal transduction in the nervous system.	J. Thromb. Haemost.	7 Suppl 1:151-4	2009	19630789		J K Ryu, D Davalos, K Akassoglou	J K Ryu	K Akassoglou	Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94158, USA.	NINDS NIH HHS; R01 NS052189-07
Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD	Acute vascular disruption and aquaporin 4 loss after stroke.	Stroke	40:6:2182-90	2009	19372455		Beth Friedman, Christian Schachtrup, Philbert S Tsai, Andy Y Shih, Katerina Akassoglou, David Kleinfeld, Patrick D Lyden	Beth Friedman	Patrick D Lyden	Department of Neurosciences, UCSD School of Medicine, San Diego, CA, USA.	NINDS NIH HHS; R21 NS052565-01
Gaultier A, Wu X, Le Moan N, Takimoto S, Mukandala G, Akassoglou K, Campana WM, Gonias SL	Low-density lipoprotein receptor-related protein 1 is an essential receptor for myelin phagocytosis.	J. Cell. Sci.	122:Pt 8:1155-62	2009	19299462		Alban Gaultier, Xiaohua Wu, Natacha Le Moan, Shinako Takimoto, Gatambwa Mukandala, Katerina Akassoglou, W Marie Campana, Steven L Gonias	Alban Gaultier	Steven L Gonias	Department of Pathology, University of California, San Diego, La Jolla, CA 92093, USA.	NINDS NIH HHS; R01 NS-054671
Xu M, Remillard CV, Sachs BD, Makino A, Platoshyn O, Yao W, Dillmann WH, Akassoglou K, Yuan JX	p75 neurotrophin receptor regulates agonist-induced pulmonary vasoconstriction.	Am. J. Physiol. Heart Circ. Physiol.	295:4:H1529-38	2008	18689502		Minlin Xu, Carmelle V Remillard, Benjamin D Sachs, Ayako Makino, Oleksandr Platoshyn, Weijuan Yao, Wolfgang H Dillmann, Katerina Akassoglou, Jason X-J Yuan	Minlin Xu	Jason X-J Yuan	Departments of Medicine, University of California-San Diego, La Jolla, California 92093-0725, USA.	NINDS NIH HHS; NS51470
Rius J, Guma M, Schachtrup C, Akassoglou K, Zinkernagel AS, Nizet V, Johnson RS, Haddad GG, Karin M	NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha.	Nature	453:7196:807-11	2008	18432192		Jordi Rius, Monica Guma, Christian Schachtrup, Katerina Akassoglou, Annelies S Zinkernagel, Victor Nizet, Randall S Johnson, Gabriel G Haddad, Michael Karin	Jordi Rius	Michael Karin	Laboratory of Gene Regulation and Signal Transduction, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093-0723, USA.	NCI NIH HHS; R01 CA118165-05
Davalos D, Lee JK, Smith WB, Brinkman B, Ellisman MH, Zheng B, Akassoglou K	Stable in vivo imaging of densely populated glia, axons and blood vessels in the mouse spinal cord using two-photon microscopy.	J. Neurosci. Methods	169:1:1-7	2008	18192022		Dimitrios Davalos, Jae K Lee, W Bryan Smith, Brendan Brinkman, Mark H Ellisman, Binhai Zheng, Katerina Akassoglou	Dimitrios Davalos	Katerina Akassoglou	Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA. davalos@ucsd.edu	NCRR NIH HHS; RR04050
Xu M, Platoshyn O, Makino A, Dillmann WH, Akassoglou K, Remillard CV, Yuan JX	Characterization of agonist-induced vasoconstriction in mouse pulmonary artery.	Am. J. Physiol. Heart Circ. Physiol.	294:1:H220-8	2008	17982012		Minlin Xu, Oleksandr Platoshyn, Ayako Makino, Wolfgang H Dillmann, Katerina Akassoglou, Carmelle V Remillard, Jason X-J Yuan	Minlin Xu	Jason X-J Yuan	Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0725, USA.	NHLBI NIH HHS; HL 066012
Sachs BD, Akassoglou K	Regulation of cAMP by the p75 neurotrophin receptor: insight into drug design of selective phosphodiesterase inhibitors.	Biochem. Soc. Trans.	35:Pt 5:1273-7	2007	17956328		B D Sachs, K Akassoglou	B D Sachs	K Akassoglou	Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-90636, U.S.A.	NINDS NIH HHS; NS51470
Schachtrup C, Lu P, Jones LL, Lee JK, Lu J, Sachs BD, Zheng B, Akassoglou K	Fibrinogen inhibits neurite outgrowth via beta 3 integrin-mediated phosphorylation of the EGF receptor.	Proc. Natl. Acad. Sci. U.S.A.	104:28:11814-9	2007	17606926		Christian Schachtrup, Paul Lu, Leonard L Jones, Jae K Lee, Jerry Lu, Ben D Sachs, Binhai Zheng, Katerina Akassoglou	Christian Schachtrup	Katerina Akassoglou	Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093, USA.	NINDS NIH HHS; R01NS052189
Sachs BD, Baillie GS, McCall JR, Passino MA, Schachtrup C, Wallace DA, Dunlop AJ, MacKenzie KF, Klussmann E, Lynch MJ, Sikorski SL, Nuriel T, Tsigelny I, Zhang J, Houslay MD, Chao MV, Akassoglou K	p75 neurotrophin receptor regulates tissue fibrosis through inhibition of plasminogen activation via a PDE4/cAMP/PKA pathway.	J. Cell Biol.	177:6:1119-32	2007	17576803		Benjamin D Sachs, George S Baillie, Julianne R McCall, Melissa A Passino, Christian Schachtrup, Derek A Wallace, Allan J Dunlop, Kirsty F MacKenzie, Enno Klussmann, Martin J Lynch, Shoana L Sikorski, Tal Nuriel, Igor Tsigelny, Jin Zhang, Miles D Houslay, Moses V Chao, Katerina Akassoglou	Benjamin D Sachs	Katerina Akassoglou	Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.	NINDS NIH HHS; NS52189
Passino MA, Adams RA, Sikorski SL, Akassoglou K	Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR.	Science	315:5820:1853-6	2007	17395831		Melissa A Passino, Ryan A Adams, Shoana L Sikorski, Katerina Akassoglou	Melissa A Passino	Katerina Akassoglou	Department of Pharmacology, University of California, San Diego (UCSD), La Jolla, CA 92093-0636, USA.	NINDS NIH HHS; P30-NS047101
Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K	The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease.	J. Exp. Med.	204:3:571-82	2007	17339406		Ryan A Adams, Jan Bauer, Matthew J Flick, Shoana L Sikorski, Tal Nuriel, Hans Lassmann, Jay L Degen, Katerina Akassoglou	Ryan A Adams	Katerina Akassoglou	Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA.	NINDS NIH HHS; R01 NS052189
Adams RA, Schachtrup C, Davalos D, Tsigelny I, Akassoglou K	Fibrinogen signal transduction as a mediator and therapeutic target in inflammation: lessons from multiple sclerosis.	Curr. Med. Chem.	14:27:2925-36	2007	18045138		R A Adams, C Schachtrup, D Davalos, I Tsigelny, K Akassoglou	R A Adams	K Akassoglou	Department of Pharmacology, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0636, USA.	NINDS NIH HHS; NS052189
Arthur DB, Akassoglou K, Insel PA	P2Y2 and TrkA receptors interact with Src family kinase for neuronal differentiation.	Biochem. Biophys. Res. Commun.	347:3:678-82	2006	16842754		David B Arthur, Katerina Akassoglou, Paul A Insel	David B Arthur	Paul A Insel	Department of Pharmacology, University of California, San Diego, La Jolla, 92093, USA.	NA
Arthur DB, Georgi S, Akassoglou K, Insel PA	Inhibition of apoptosis by P2Y2 receptor activation: novel pathways for neuronal survival.	J. Neurosci.	26:14:3798-804	2006	16597733		David B Arthur, Sean Georgi, Katerina Akassoglou, Paul A Insel	David B Arthur	Paul A Insel	Department of Pharmacology, University of California, San Diego, La Jolla, California 92093, USA.	NINDS NIH HHS; R01-NS051470
Arthur DB, Akassoglou K, Insel PA	P2Y2 receptor activates nerve growth factor/TrkA signaling to enhance neuronal differentiation.	Proc. Natl. Acad. Sci. U.S.A.	102:52:19138-43	2005	16365320		David B Arthur, Katerina Akassoglou, Paul A Insel	David B Arthur	Paul A Insel	Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093-0636, USA.	NCRR NIH HHS; RR04050
Akassoglou K	Nerve growth factor-independent neuronal survival: a role for NO donors.	Mol. Pharmacol.	68:4:952-5	2005	16046659		Katerina Akassoglou	Katerina Akassoglou	Katerina Akassoglou	Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093-0636, USA. akass@ucsd.edu	NA
Adams RA, Passino M, Sachs BD, Nuriel T, Akassoglou K	Fibrin mechanisms and functions in nervous system pathology.	Mol. Interv.	4:3:163-76	2004	15210870		Ryan A Adams, Melissa Passino, Benjamin D Sachs, Tal Nuriel, Katerina Akassoglou	Ryan A Adams	Katerina Akassoglou	Department of Pharmacology, University of California-San Diego, La Jolla, CA 92093-0636, USA.	NA
Akassoglou K, Adams RA, Bauer J, Mercado P, Tseveleki V, Lassmann H, Probert L, Strickland S	Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis.	Proc. Natl. Acad. Sci. U.S.A.	101:17:6698-703	2004	15096619		Katerina Akassoglou, Ryan A Adams, Jan Bauer, Peter Mercado, Vivian Tseveleki, Hans Lassmann, Lesley Probert, Sidney Strickland	Katerina Akassoglou	Sidney Strickland	Department of Pharmacology, University of California at San Diego, La Jolla, CA 92093-0636, USA. akass@ucsd.edu	NCRR NIH HHS; RR04050
Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV	Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration.	Proc. Natl. Acad. Sci. U.S.A.	101:14:5075-80	2004	15051870		Katerina Akassoglou, Brian Malester, Jixiang Xu, Lino Tessarollo, Jack Rosenbluth, Moses V Chao	Katerina Akassoglou	Moses V Chao	Molecular Neurobiology Program, Skirball Institute of Biomolecular Medicine, Department of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.	NINDS NIH HHS; NS37475
Akassoglou K, Akpinar P, Murray S, Strickland S	Fibrin is a regulator of Schwann cell migration after sciatic nerve injury in mice.	Neurosci. Lett.	338:3:185-8	2003	12581827		Katerina Akassoglou, Pinar Akpinar, Simon Murray, Sidney Strickland	Katerina Akassoglou	Sidney Strickland	Laboratory of Neurobiology and Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA. akass@saturn.med.nyu.edu	NA
Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, Probert L	Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice.	Proc. Natl. Acad. Sci. U.S.A.	100:2:709-14	2003	12522266		Katerina Akassoglou, Eleni Douni, Jan Bauer, Hans Lassmann, George Kollias, Lesley Probert	Katerina Akassoglou	Lesley Probert	Laboratory of Molecular Genetics, Hellenic Pasteur Institute, 127 Vassilissis Sofias Avenue, Athens 11521, Greece.	NA
Akassoglou K, Yu WM, Akpinar P, Strickland S	Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation.	Neuron	33:6:861-75	2002	11906694		Katerina Akassoglou, Wei Ming Yu, Pinar Akpinar, Sidney Strickland	Katerina Akassoglou	Sidney Strickland	Laboratory of Neurobiology and Genetics, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.	NINDS NIH HHS; R01 NS035704
Akassoglou K, Strickland S	Nervous system pathology: the fibrin perspective.	Biol. Chem.	383:1:37-45	2002	11928820		Katerina Akassoglou, Sidney Strickland	Katerina Akassoglou	Sidney Strickland	Laboratory of Neurobiology and Genetics, The Rockefeller University, New York, NY 10021, USA.	NINDS NIH HHS; NS38472
Probert L, Akassoglou K	Glial expression of tumor necrosis factor in transgenic animals: how do these models reflect the "normal situation"?	Glia	36:2:212-9	2001	11596129		L Probert, K Akassoglou	L Probert	K Akassoglou	Laboratory of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece. lesley_probert@hol.gr	NA
Brodsky S, Chen J, Lee A, Akassoglou K, Norman J, Goligorsky MS	Plasmin-dependent and -independent effects of plasminogen activators and inhibitor-1 on ex vivo angiogenesis.	Am. J. Physiol. Heart Circ. Physiol.	281:4:H1784-92	2001	11557572		S Brodsky, J Chen, A Lee, K Akassoglou, J Norman, M S Goligorsky	S Brodsky	M S Goligorsky	Department of Medicine, State University of New York, Stony Brook, New York 11794-8152, USA.	NIDDK NIH HHS; DK-54602
Probert L, Eugster HP, Akassoglou K, Bauer J, Frei K, Lassmann H, Fontana A	TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease.	Brain	123 ( Pt 10):2005-19	2000	11004118		L Probert, H P Eugster, K Akassoglou, J Bauer, K Frei, H Lassmann, A Fontana	L Probert	A Fontana	Department of Molecular Genetics and Immunology, Hellenic Pasteur Institute, Athens, Greece.	NA
Akassoglou K, Kombrinck KW, Degen JL, Strickland S	Tissue plasminogen activator-mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury.	J. Cell Biol.	149:5:1157-66	2000	10831618		K Akassoglou, K W Kombrinck, J L Degen, S Strickland	K Akassoglou	S Strickland	Department of Pharmacology, State University of New York at Stony Brook, Stony Brook, New York 11794-8651, USA.	NA
Aloe L, Properzi F, Probert L, Akassoglou K, Kassiotis G, Micera A, Fiore M	Learning abilities, NGF and BDNF brain levels in two lines of TNF-alpha transgenic mice, one characterized by neurological disorders, the other phenotypically normal.	Brain Res.	840:1-2:125-37	1999	10517960		L Aloe, F Properzi, L Probert, K Akassoglou, G Kassiotis, A Micera, M Fiore	L Aloe	M Fiore	Institute of Neurobiology, CNR, viale Marx, 43-15, 00137, Rome, Italy. aloe@in.rm.cnr.it	NA
Kassiotis G, Bauer J, Akassoglou K, Lassmann H, Kollias G, Probert L	A tumor necrosis factor-induced model of human primary demyelinating diseases develops in immunodeficient mice.	Eur. J. Immunol.	29:3:912-7	1999	10092095		G Kassiotis, J Bauer, K Akassoglou, H Lassmann, G Kollias, L Probert	G Kassiotis	L Probert	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Akassoglou K, Bauer J, Kassiotis G, Lassmann H, Kollias G, Probert L	Transgenic models of TNF induced demyelination.	Adv. Exp. Med. Biol.	468:245-59	1999	10635034		K Akassoglou, J Bauer, G Kassiotis, H Lassmann, G Kollias, L Probert	K Akassoglou	L Probert	Laboratory of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G, Probert L	Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy.	Am. J. Pathol.	153:3:801-13	1998	9736029		K Akassoglou, J Bauer, G Kassiotis, M Pasparakis, H Lassmann, G Kollias, L Probert	K Akassoglou	L Probert	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Probert L, Akassoglou K, Kassiotis G, Pasparakis M, Alexopoulou L, Kollias G	TNF-alpha transgenic and knockout models of CNS inflammation and degeneration.	J. Neuroimmunol.	72:2:137-41	1997	9042105		L Probert, K Akassoglou, G Kassiotis, M Pasparakis, L Alexopoulou, G Kollias	L Probert	G Kollias	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece. lesley_probert@prometheus.hol.gr	NA
Akassoglou K, Probert L, Kontogeorgos G, Kollias G	Astrocyte-specific but not neuron-specific transmembrane TNF triggers inflammation and degeneration in the central nervous system of transgenic mice.	J. Immunol.	158:1:438-45	1997	8977220		K Akassoglou, L Probert, G Kontogeorgos, G Kollias	K Akassoglou	G Kollias	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Fiore M, Probert L, Kollias G, Akassoglou K, Alleva E, Aloe L	Neurobehavioral alterations in developing transgenic mice expressing TNF-alpha in the brain.	Brain Behav. Immun.	10:2:126-38	1996	8811936		M Fiore, L Probert, G Kollias, K Akassoglou, E Alleva, L Aloe	M Fiore	L Aloe	Institute of Neurobiology, CNR, viale Marx 15, Rome, 00156, Italy.	NA
Probert L, Akassoglou K, Alexopoulou L, Douni E, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Kollias G	Dissection of the pathologies induced by transmembrane and wild-type tumor necrosis factor in transgenic mice.	J. Leukoc. Biol.	59:4:518-25	1996	8613699		L Probert, K Akassoglou, L Alexopoulou, E Douni, S Haralambous, S Hill, G Kassiotis, D Kontoyiannis, M Pasparakis, D Plows, G Kollias	L Probert	G Kollias	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Probert L, Akassoglou K, Pasparakis M, Kontogeorgos G, Kollias G	Spontaneous inflammatory demyelinating disease in transgenic mice showing central nervous system-specific expression of tumor necrosis factor alpha.	Proc. Natl. Acad. Sci. U.S.A.	92:24:11294-8	1995	7479982		L Probert, K Akassoglou, M Pasparakis, G Kontogeorgos, G Kollias	L Probert	G Kollias	Department of Molecular Genetics, Hellenic Pasteur Institutte, Athens, Greece.	NA
Douni E, Akassoglou K, Alexopoulou L, Georgopoulos S, Haralambous S, Hill S, Kassiotis G, Kontoyiannis D, Pasparakis M, Plows D, Probert L, Kollias G	Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.	J. Inflamm.	47:1-2:27-38		8913927		E Douni, K Akassoglou, L Alexopoulou, S Georgopoulos, S Haralambous, S Hill, G Kassiotis, D Kontoyiannis, M Pasparakis, D Plows, L Probert, G Kollias	E Douni	G Kollias	Department of Molecular Genetics, Hellenic Pasteur Institute, Athens, Greece.	NA
Suberbielle E, Sanchez PE, Kravitz AV, Wang X, Ho K, Eilertson K, Devidze N, Kreitzer AC, Mucke L	Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β.	Nat. Neurosci.	16:5:613-21	2013	23525040		Elsa Suberbielle, Pascal E Sanchez, Alexxai V Kravitz, Xin Wang, Kaitlyn Ho, Kirsten Eilertson, Nino Devidze, Anatol C Kreitzer, Lennart Mucke	Elsa Suberbielle	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California, USA.	NIA NIH HHS; R01 AG011385
Morris M, Hamto P, Adame A, Devidze N, Masliah E, Mucke L	Age-appropriate cognition and subtle dopamine-independent motor deficits in aged Tau knockout mice.	Neurobiol. Aging	34:6:1523-9	2013	23332171		Meaghan Morris, Patricia Hamto, Anthony Adame, Nino Devidze, Eliezer Masliah, Lennart Mucke	Meaghan Morris	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; R37 AG018440
Harris JA, Koyama A, Maeda S, Ho K, Devidze N, Dubal DB, Yu GQ, Masliah E, Mucke L	Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits.	PLoS ONE	7:9:e45881	2012	23029293		Julie A Harris, Akihiko Koyama, Sumihiro Maeda, Kaitlyn Ho, Nino Devidze, Dena B Dubal, Gui-Qiu Yu, Eliezer Masliah, Lennart Mucke	Julie A Harris	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA, USA.	NINDS NIH HHS; NS065780
Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L	Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.	Proc. Natl. Acad. Sci. U.S.A.	109:42:E2895-903	2012	22869752		Pascal E Sanchez, Lei Zhu, Laure Verret, Keith A Vossel, Anna G Orr, John R Cirrito, Nino Devidze, Kaitlyn Ho, Gui-Qiu Yu, Jorge J Palop, Lennart Mucke	Pascal E Sanchez	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928-01
Mucke L, Selkoe DJ	Neurotoxicity of amyloid β-protein: synaptic and network dysfunction.	Cold Spring Harb Perspect Med	2:7:a006338	2012	22762015		Lennart Mucke, Dennis J Selkoe	Lennart Mucke	Dennis J Selkoe	Gladstone Institute of Neurological Disease and University of California, San Francisco, San Francisco, California, USA. lmucke@gladstone.ucsf.edu	NA
Verret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ	Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model.	Cell	149:3:708-21	2012	22541439		Laure Verret, Edward O Mann, Giao B Hang, Albert M I Barth, Inma Cobos, Kaitlyn Ho, Nino Devidze, Eliezer Masliah, Anatol C Kreitzer, Istvan Mody, Lennart Mucke, Jorge J Palop	Laure Verret	Jorge J Palop	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; P01 AG022074-09
Huang Y, Mucke L	Alzheimer mechanisms and therapeutic strategies.	Cell	148:6:1204-22	2012	22424230		Yadong Huang, Lennart Mucke	Yadong Huang	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; P01 AG022074-10
Minami SS, Sun B, Popat K, Kauppinen T, Pleiss M, Zhou Y, Ward ME, Floreancig P, Mucke L, Desai T, Gan L	Selective targeting of microglia by quantum dots.	J Neuroinflammation	9:22	2012	22272874		S Sakura Minami, Binggui Sun, Ketul Popat, Tiina Kauppinen, Mike Pleiss, Yungui Zhou, Michael E Ward, Paul Floreancig, Lennart Mucke, Tejal Desai, Li Gan	S Sakura Minami	Li Gan	Gladstone Institute of Neurological Disease, 1650 Owens St., San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928-01
Morris M, Koyama A, Masliah E, Mucke L	Tau reduction does not prevent motor deficits in two mouse models of Parkinson's disease.	PLoS ONE	6:12:e29257	2011	22206005		Meaghan Morris, Akihiko Koyama, Eliezer Masliah, Lennart Mucke	Meaghan Morris	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California, United States of America.	NINDS NIH HHS; NS065780
Cissé M, Sanchez PE, Kim DH, Ho K, Yu GQ, Mucke L	Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice.	J. Neurosci.	31:29:10427-31	2011	21775587		Moustapha Cissé, Pascal E Sanchez, Daniel H Kim, Kaitlyn Ho, Gui-Qiu Yu, Lennart Mucke	Moustapha Cissé	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, California 94158, USA.	NCRR NIH HHS; RR18928
Morris M, Maeda S, Vossel K, Mucke L	The many faces of tau.	Neuron	70:3:410-26	2011	21555069		Meaghan Morris, Sumihiro Maeda, Keith Vossel, Lennart Mucke	Meaghan Morris	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NINDS NIH HHS; R01 NS041787-12
Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu GQ, Palop JJ, Noebels JL, Mucke L	Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.	J. Neurosci.	31:2:700-11	2011	21228179		Erik D Roberson, Brian Halabisky, Jong W Yoo, Jinghua Yao, Jeannie Chin, Fengrong Yan, Tiffany Wu, Patricia Hamto, Nino Devidze, Gui-Qiu Yu, Jorge J Palop, Jeffrey L Noebels, Lennart Mucke	Erik D Roberson	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA. eroberson@uab.edu	NCRR NIH HHS; RR018928
Palop JJ, Mucke L, Roberson ED	Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling.	Methods Mol. Biol.	670:245-62	2011	20967595		Jorge J Palop, Lennart Mucke, Erik D Roberson	Jorge J Palop	Erik D Roberson	Department of Neurology, Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA, USA.	NINDS NIH HHS; NS054811
Cissé M, Halabisky B, Harris J, Devidze N, Dubal DB, Sun B, Orr A, Lotz G, Kim DH, Hamto P, Ho K, Yu GQ, Mucke L	Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.	Nature	469:7328:47-52	2011	21113149		Moustapha Cissé, Brian Halabisky, Julie Harris, Nino Devidze, Dena B Dubal, Binggui Sun, Anna Orr, Gregor Lotz, Daniel H Kim, Patricia Hamto, Kaitlyn Ho, Gui-Qiu Yu, Lennart Mucke	Moustapha Cissé	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA.	NCRR NIH HHS; RR18928-01
Harris JA, Devidze N, Verret L, Ho K, Halabisky B, Thwin MT, Kim D, Hamto P, Lo I, Yu GQ, Palop JJ, Masliah E, Mucke L	Transsynaptic progression of amyloid-β-induced neuronal dysfunction within the entorhinal-hippocampal network.	Neuron	68:3:428-41	2010	21040845		Julie A Harris, Nino Devidze, Laure Verret, Kaitlyn Ho, Brian Halabisky, Myo T Thwin, Daniel Kim, Patricia Hamto, Iris Lo, Gui-Qiu Yu, Jorge J Palop, Eliezer Masliah, Lennart Mucke	Julie A Harris	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; R37 AG011385-18
Vossel KA, Zhang K, Brodbeck J, Daub AC, Sharma P, Finkbeiner S, Cui B, Mucke L	Tau reduction prevents Abeta-induced defects in axonal transport.	Science	330:6001:198	2010	20829454		Keith A Vossel, Kai Zhang, Jens Brodbeck, Aaron C Daub, Punita Sharma, Steven Finkbeiner, Bianxiao Cui, Lennart Mucke	Keith A Vossel	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. kvossel@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS041787-09
Palop JJ, Mucke L	Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks.	Nat. Neurosci.	13:7:812-8	2010	20581818		Jorge J Palop, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, California, USA. jpalop@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS041787-11
Buttini M, Masliah E, Yu GQ, Palop JJ, Chang S, Bernardo A, Lin C, Wyss-Coray T, Huang Y, Mucke L	Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice.	Am. J. Pathol.	177:2:563-9	2010	20595630		Manuel Buttini, Eliezer Masliah, Gui-Qiu Yu, Jorge J Palop, Shengjun Chang, Aubrey Bernardo, Carol Lin, Tony Wyss-Coray, Yadong Huang, Lennart Mucke	Manuel Buttini	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158-2261, USA. manuel.buttini@elan.com	NINDS NIH HHS; R01 NS041787-09
Sanchez-Mejia RO, Mucke L	Phospholipase A2 and arachidonic acid in Alzheimer's disease.	Biochim. Biophys. Acta	1801:8:784-90	2010	20553961		Rene O Sanchez-Mejia, Lennart Mucke	Rene O Sanchez-Mejia	Lennart Mucke	Scripps Clinic and The Scripps Research Institute, La Jolla, CA 92037, USA.	NINDS NIH HHS; R01 NS041787-09
Harris JA, Devidze N, Halabisky B, Lo I, Thwin MT, Yu GQ, Bredesen DE, Masliah E, Mucke L	Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein.	J. Neurosci.	30:1:372-81	2010	20053918		Julie A Harris, Nino Devidze, Brian Halabisky, Iris Lo, Myo T Thwin, Gui-Qiu Yu, Dale E Bredesen, Eliezer Masliah, Lennart Mucke	Julie A Harris	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, California 94158, USA.	NIA NIH HHS; R37 AG011385-18
Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, Mucke L, Gan L	Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease.	Cell Stem Cell	5:6:624-33	2009	19951690		Binggui Sun, Brian Halabisky, Yungui Zhou, Jorge J Palop, Guiqiu Yu, Lennart Mucke, Li Gan	Binggui Sun	Li Gan	Gladstone Institute of Neurological Disease, University of California, San Francisco, 94158, USA.	NIA NIH HHS; P01 AG004342-140009
Palop JJ, Mucke L	Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?	Neuromolecular Med.	12:1:48-55	2010	19838821		Jorge J Palop, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease and University of California, San Francisco, California, USA. jpalop@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS041787-11
Mucke L	Neuroscience: Alzheimer's disease.	Nature	461:7266:895-7	2009	19829367		Lennart Mucke	Lennart Mucke	Lennart Mucke		NA
Khachaturian ZS, Snyder PJ, Doody R, Aisen P, Comer M, Dwyer J, Frank RA, Holzapfel A, Khachaturian AS, Korczyn AD, Roses A, Simpkins JW, Schneider LS, Albert MS, Egge R, Deves A, Ferris S, Greenberg BD, Johnson C, Kukull WA, Poirier J, Schenk D, Thies W, Gauthier S, Gilman S, Bernick C, Cummings JL, Fillit H, Grundman M, Kaye J, Mucke L, Reisberg B, Sano M, Pickeral O, Petersen RC, Mohs RC, Carrillo M, Corey-Bloom JP, Foster NL, Jacobsen S, Lee V, Potter WZ, Sabbagh MN, Salmon D, Trojanowski JQ, Wexler N, Bain LJ	A roadmap for the prevention of dementia II: Leon Thal Symposium 2008.	Alzheimers Dement	5:2:85-92	2009	19328434		Zaven S Khachaturian, Peter J Snyder, Rachelle Doody, Paul Aisen, Meryl Comer, John Dwyer, Richard A Frank, Andrew Holzapfel, Ara S Khachaturian, Amos D Korczyn, Allen Roses, James W Simpkins, Lon S Schneider, Marilyn S Albert, Robert Egge, Aaron Deves, Steven Ferris, Barry D Greenberg, Carl Johnson, Walter A Kukull, Judes Poirier, Dale Schenk, William Thies, Serge Gauthier, Sid Gilman, Charles Bernick, Jeffrey L Cummings, Howard Fillit, Michael Grundman, Jeff Kaye, Lennart Mucke, Barry Reisberg, Mary Sano, Oxana Pickeral, Ronald C Petersen, Richard C Mohs, Maria Carrillo, Jody P Corey-Bloom, Norman L Foster, Steve Jacobsen, Virginia Lee, William Z Potter, Marwan N Sabbagh, David Salmon, John Q Trojanowski, Nancy Wexler, Lisa J Bain	Zaven S Khachaturian	Lisa J Bain	Lou Ruvo Brain Institute, Las Vegas, NV 89106, USA. zkhachaturian@keepmemoryalive.org	NA
Cisse M, Mucke L	Alzheimer's disease: A prion protein connection.	Nature	457:7233:1090-1	2009	19242462		Moustapha Cisse, Lennart Mucke	Moustapha Cisse	Lennart Mucke		NA
Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce-Levie K, Cheng IH, Yu GQ, Mucke L	Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.	J. Neurosci.	29:7:1977-86	2009	19228952		William J Meilandt, Moustapha Cisse, Kaitlyn Ho, Tiffany Wu, Luke A Esposito, Kimberly Scearce-Levie, Irene H Cheng, Gui-Qiu Yu, Lennart Mucke	William J Meilandt	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NCRR NIH HHS; RR018928
Palop JJ, Mucke L	Epilepsy and cognitive impairments in Alzheimer disease.	Arch. Neurol.	66:4:435-40	2009	19204149		Jorge J Palop, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, CA 94158, USA. jpalop@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS041787-08
Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L	Collagen VI protects neurons against Abeta toxicity.	Nat. Neurosci.	12:2:119-21	2009	19122666		Jason S Cheng, Dena B Dubal, Daniel H Kim, Justin Legleiter, Irene H Cheng, Gui-Qiu Yu, Ina Tesseur, Tony Wyss-Coray, Paolo Bonaldo, Lennart Mucke	Jason S Cheng	Lennart Mucke	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, California 94158, USA.	Howard Hughes Medical Institute; 
Sanchez-Mejia RO, Newman JW, Toh S, Yu GQ, Zhou Y, Halabisky B, Cissé M, Scearce-Levie K, Cheng IH, Gan L, Palop JJ, Bonventre JV, Mucke L	Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease.	Nat. Neurosci.	11:11:1311-8	2008	18931664		Rene O Sanchez-Mejia, John W Newman, Sandy Toh, Gui-Qiu Yu, Yungui Zhou, Brian Halabisky, Moustapha Cissé, Kimberly Scearce-Levie, Irene H Cheng, Li Gan, Jorge J Palop, Joseph V Bonventre, Lennart Mucke	Rene O Sanchez-Mejia	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA. rene_sanchez@post.harvard.edu	NIA NIH HHS; R37 AG011385-15
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB	Genes contributing to prion pathogenesis.	J. Gen. Virol.	89:Pt 7:1777-88	2008	18559949		Gültekin Tamgüney, Kurt Giles, David V Glidden, Pierre Lessard, Holger Wille, Patrick Tremblay, Darlene F Groth, Fruma Yehiely, Carsten Korth, Richard C Moore, Jörg Tatzelt, Eric Rubinstein, Claude Boucheix, Xiaoping Yang, Pamela Stanley, Michael P Lisanti, Raymond A Dwek, Pauline M Rudd, Jackob Moskovitz, Charles J Epstein, Tracey Dawson Cruz, William A Kuziel, Nobuyo Maeda, Jan Sap, Karen Hsiao Ashe, George A Carlson, Ina Tesseur, Tony Wyss-Coray, Lennart Mucke, Karl H Weisgraber, Robert W Mahley, Fred E Cohen, Stanley B Prusiner	Gültekin Tamgüney	Stanley B Prusiner	Institute for Neurodegenerative Diseases, University of California, San Francisco, CA, USA.	NIA NIH HHS; P01 AG021601-03
Meilandt WJ, Yu GQ, Chin J, Roberson ED, Palop JJ, Wu T, Scearce-Levie K, Mucke L	Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease.	J. Neurosci.	28:19:5007-17	2008	18463254		William J Meilandt, Gui-Qiu Yu, Jeannie Chin, Erik D Roberson, Jorge J Palop, Tiffany Wu, Kimberly Scearce-Levie, Lennart Mucke	William J Meilandt	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA.	NCRR NIH HHS; RR018928
Gan L, Mucke L	Paths of convergence: sirtuins in aging and neurodegeneration.	Neuron	58:1:10-4	2008	18400158		Li Gan, Lennart Mucke	Li Gan	Lennart Mucke	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, CA 94158, USA. lgan@gladstone.ucsf.edu	NINDS NIH HHS; NS041787
Scearce-Levie K, Roberson ED, Gerstein H, Cholfin JA, Mandiyan VS, Shah NM, Rubenstein JL, Mucke L	Abnormal social behaviors in mice lacking Fgf17.	Genes Brain Behav.	7:3:344-54	2008	17908176		K Scearce-Levie, E D Roberson, H Gerstein, J A Cholfin, V S Mandiyan, N M Shah, J L R Rubenstein, L Mucke	K Scearce-Levie	L Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158-2261, USA. kscearce-levie@gladstone.ucsf.edu	NINDS NIH HHS; NS34661-01A1
Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L	Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease.	Neuron	55:5:697-711	2007	17785178		Jorge J Palop, Jeannie Chin, Erik D Roberson, Jun Wang, Myo T Thwin, Nga Bien-Ly, Jong Yoo, Kaitlyn O Ho, Gui-Qiu Yu, Anatol Kreitzer, Steven Finkbeiner, Jeffrey L Noebels, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. jpalop@gladstone.ucsf.edu	NCRR NIH HHS; RR018928
deIpolyi AR, Rankin KP, Mucke L, Miller BL, Gorno-Tempini ML	Spatial cognition and the human navigation network in AD and MCI.	Neurology	69:10:986-97	2007	17785667		A R deIpolyi, K P Rankin, L Mucke, B L Miller, M L Gorno-Tempini	A R deIpolyi	M L Gorno-Tempini	Gladstone Institute of Neurological Disease, Department of Neurology, University of California, San Francisco, CA 94143-1207, USA.	NINDS NIH HHS; R01 NS050915
Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, Bien-Ly N, Puoliväli J, Lesné S, Ashe KH, Muchowski PJ, Mucke L	Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.	J. Biol. Chem.	282:33:23818-28	2007	17548355		Irene H Cheng, Kimberly Scearce-Levie, Justin Legleiter, Jorge J Palop, Hilary Gerstein, Nga Bien-Ly, Jukka Puoliväli, Sylvain Lesné, Karen H Ashe, Paul J Muchowski, Lennart Mucke	Irene H Cheng	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA.	NCRR NIH HHS; RR 18928-01
Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L	Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model.	Science	316:5825:750-4	2007	17478722		Erik D Roberson, Kimberly Scearce-Levie, Jorge J Palop, Fengrong Yan, Irene H Cheng, Tiffany Wu, Hilary Gerstein, Gui-Qiu Yu, Lennart Mucke	Erik D Roberson	Lennart Mucke	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. eroberson@gladstone.ucsf.edu	NCRR NIH HHS; RR18928-01
Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L	Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.	J. Neurosci.	27:11:2727-33	2007	17360894		Jeannie Chin, Catherine M Massaro, Jorge J Palop, Myo T Thwin, Gui-Qiu Yu, Nga Bien-Ly, Aaron Bender, Lennart Mucke	Jeannie Chin	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, California 94158, USA.	NCRR NIH HHS; RR018928
Deipolyi AR, Fang S, Palop JJ, Yu GQ, Wang X, Mucke L	Altered navigational strategy use and visuospatial deficits in hAPP transgenic mice.	Neurobiol. Aging	29:2:253-66	2008	17126954		Amy R Deipolyi, Shanna Fang, Jorge J Palop, Gui-Qiu Yu, Xin Wang, Lennart Mucke	Amy R Deipolyi	Lennart Mucke	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NINDS NIH HHS; NS041787
Roberson ED, Mucke L	100 years and counting: prospects for defeating Alzheimer's disease.	Science	314:5800:781-4	2006	17082448		Erik D Roberson, Lennart Mucke	Erik D Roberson	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, CA 94158, USA.	NINDS NIH HHS; NS054811
Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T	Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.	J. Clin. Invest.	116:11:3060-9	2006	17080199		Ina Tesseur, Kun Zou, Luke Esposito, Frederique Bard, Elisabeth Berber, Judith Van Can, Amy H Lin, Leslie Crews, Patrick Tremblay, Paul Mathews, Lennart Mucke, Eliezer Masliah, Tony Wyss-Coray	Ina Tesseur	Tony Wyss-Coray	Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA.	NINDS NIH HHS; NS40994
Palop JJ, Chin J, Mucke L	A network dysfunction perspective on neurodegenerative diseases.	Nature	443:7113:768-73	2006	17051202		Jorge J Palop, Jeannie Chin, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, California 94158, USA.	NA
Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L	Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease.	Neuron	51:6:703-14	2006	16982417		Sarah Mueller-Steiner, Yungui Zhou, Hideaki Arai, Erik D Roberson, Binggui Sun, Jennifer Chen, Xin Wang, Guiqiu Yu, Luke Esposito, Lennart Mucke, Li Gan	Sarah Mueller-Steiner	Li Gan	Gladstone Institute of Neurological Disease, University of California, San Francisco, 1650 Owens Street, 94158, USA.	NIA NIH HHS; R21 AG024447
Choi DS, Wang D, Yu GQ, Zhu G, Kharazia VN, Paredes JP, Chang WS, Deitchman JK, Mucke L, Messing RO	PKCepsilon increases endothelin converting enzyme activity and reduces amyloid plaque pathology in transgenic mice.	Proc. Natl. Acad. Sci. U.S.A.	103:21:8215-20	2006	16698938		Doo-Sup Choi, Dan Wang, Gui-Qui Yu, Guofen Zhu, Viktor N Kharazia, J Peter Paredes, Wesley S Chang, Jason K Deitchman, Lennart Mucke, Robert O Messing	Doo-Sup Choi	Robert O Messing	Ernest Gallo Clinic and Research Center, Emeryville, CA 94608, USA.	NINDS NIH HHS; NS41787
Esposito L, Raber J, Kekonius L, Yan F, Yu GQ, Bien-Ly N, Puoliväli J, Scearce-Levie K, Masliah E, Mucke L	Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice.	J. Neurosci.	26:19:5167-79	2006	16687508		Luke Esposito, Jacob Raber, Lisa Kekonius, Fengrong Yan, Giu-Qiu Yu, Nga Bien-Ly, Jukka Puoliväli, Kimberly Scearce-Levie, Eliezer Masliah, Lennart Mucke	Luke Esposito	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NIA NIH HHS; AG022074
Morris R, Mucke L	Alzheimer's disease: A needle from the haystack.	Nature	440:7082:284-5	2006	16541054		Richard Morris, Lennart Mucke	Richard Morris	Lennart Mucke		NA
Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, Gerstein H, Scearce-Levie K, Masliah E, Mucke L	Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease.	J. Neurosci.	25:42:9694-703	2005	16237174		Jeannie Chin, Jorge J Palop, Jukka Puoliväli, Catherine Massaro, Nga Bien-Ly, Hilary Gerstein, Kimberly Scearce-Levie, Eliezer Masliah, Lennart Mucke	Jeannie Chin	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NINDS NIH HHS; NS41787
Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu GQ, Mucke L	Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice.	J. Neurosci.	25:42:9686-93	2005	16237173		Jorge J Palop, Jeannie Chin, Nga Bien-Ly, Catherine Massaro, Bertrand Z Yeung, Gui-Qiu Yu, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NINDS NIH HHS; NS41787
Chen J, Zhou Y, Mueller-Steiner S, Chen LF, Kwon H, Yi S, Mucke L, Gan L	SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling.	J. Biol. Chem.	280:48:40364-74	2005	16183991		Jennifer Chen, Yungui Zhou, Sarah Mueller-Steiner, Lin-Feng Chen, Hakju Kwon, Saili Yi, Lennart Mucke, Li Gan	Jennifer Chen	Li Gan	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NINDS NIH HHS; NS43945
Rockenstein E, Mante M, Alford M, Adame A, Crews L, Hashimoto M, Esposito L, Mucke L, Masliah E	High beta-secretase activity elicits neurodegeneration in transgenic mice despite reductions in amyloid-beta levels: implications for the treatment of Alzheimer disease.	J. Biol. Chem.	280:38:32957-67	2005	16027115		Edward Rockenstein, Michael Mante, Michael Alford, Anthony Adame, Leslie Crews, Makoto Hashimoto, Luke Esposito, Lennart Mucke, Eliezer Masliah	Edward Rockenstein	Eliezer Masliah	Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, California 92093-0624, USA.	NIA NIH HHS; AG5131
Esposito L, Gan L, Yu GQ, Essrich C, Mucke L	Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.	J. Neurochem.	91:6:1260-74	2004	15584903		Luke Esposito, Li Gan, Gui-Qiu Yu, Christian Essrich, Lennart Mucke	Luke Esposito	Lennart Mucke	Gladstone Institute of Neurological Disease, Department of Neurology, University of California, San Francisco, California, USA.	NINDS NIH HHS; NS41787
Cheng IH, Palop JJ, Esposito LA, Bien-Ly N, Yan F, Mucke L	Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation.	Nat. Med.	10:11:1190-2	2004	15502844		Irene H Cheng, Jorge J Palop, Luke A Esposito, Nga Bien-Ly, Fengrong Yan, Lennart Mucke	Irene H Cheng	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NIA NIH HHS; T32 AG00278
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, Mucke L, Li W, Schmidt AM, Kindy M, Hyslop PA, Stern DM, Du Yan SS	RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.	EMBO J.	23:20:4096-105	2004	15457210		Ottavio Arancio, Hui Ping Zhang, Xi Chen, Chang Lin, Fabrizio Trinchese, Daniela Puzzo, Shumin Liu, Ashok Hegde, Shi Fang Yan, Alan Stern, John S Luddy, Lih-Fen Lue, Douglas G Walker, Alex Roher, Manuel Buttini, Lennart Mucke, Weiying Li, Ann Marie Schmidt, Mark Kindy, Paul A Hyslop, David M Stern, Shirley Shi Du Yan	Ottavio Arancio	Shirley Shi Du Yan	Department of Psychiatry, Physiology and Neuroscience, Dementia Research Center, Nathan Kline Institute, New York University School of Medicine, NY 10032, USA.	CSR NIH HHS; IIRG-00-2076
Mucke L, Pitas RE	Food for thought: essential fatty acid protects against neuronal deficits in transgenic mouse model of AD.	Neuron	43:5:596-9	2004	15339638		Lennart Mucke, Robert E Pitas	Lennart Mucke	Robert E Pitas	Gladstone Institute of Neurological Disease, University of California, San Francisco, PO Box 419100, 94103, USA.	NA
Chin J, Palop JJ, Yu GQ, Kojima N, Masliah E, Mucke L	Fyn kinase modulates synaptotoxicity, but not aberrant sprouting, in human amyloid precursor protein transgenic mice.	J. Neurosci.	24:19:4692-7	2004	15140940		Jeannie Chin, Jorge J Palop, Gui-Qiu Yu, Nobuhiko Kojima, Eliezer Masliah, Lennart Mucke	Jeannie Chin	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, California 94141-9100, USA.	NINDS NIH HHS; NS41787
Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y	Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.	J. Neurosci.	24:10:2527-34	2004	15014128		Walter J Brecht, Faith M Harris, Shengjun Chang, Ina Tesseur, Gui-Qiu Yu, Qin Xu, Jo Dee Fish, Tony Wyss-Coray, Manuel Buttini, Lennart Mucke, Robert W Mahley, Yadong Huang	Walter J Brecht	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, California 94141-9100, USA.	NINDS NIH HHS; R21 NS046465
Huang Y, Weisgraber KH, Mucke L, Mahley RW	Apolipoprotein E: diversity of cellular origins, structural and biophysical properties, and effects in Alzheimer's disease.	J. Mol. Neurosci.	23:3:189-204	2004	15181247		Yadong Huang, Karl H Weisgraber, Lennart Mucke, Robert W Mahley	Yadong Huang	Robert W Mahley	Gladstone Institute of Neurological Disease, Gladstone Institute of Cardiovascular Disease, and the Department of Pathology, University of California, San Francisco, CA 94141-9100, USA. yhuang@gladstone.ucsf.edu	NINDS NIH HHS; NS046465
Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y	Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice.	Proc. Natl. Acad. Sci. U.S.A.	100:19:10966-71	2003	12939405		Faith M Harris, Walter J Brecht, Qin Xu, Ina Tesseur, Lisa Kekonius, Tony Wyss-Coray, Jo Dee Fish, Eliezer Masliah, Paul C Hopkins, Kimberly Scearce-Levie, Karl H Weisgraber, Lennart Mucke, Robert W Mahley, Yadong Huang	Faith M Harris	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, CA 94141-9100, USA.	NIA NIH HHS; P01 AG022074
Palop JJ, Jones B, Kekonius L, Chin J, Yu GQ, Raber J, Masliah E, Mucke L	Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits.	Proc. Natl. Acad. Sci. U.S.A.	100:16:9572-7	2003	12881482		Jorge J Palop, Brian Jones, Lisa Kekonius, Jeannie Chin, Gui-Qiu Yu, Jacob Raber, Eliezer Masliah, Lennart Mucke	Jorge J Palop	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, CA 94141, USA.	NINDS NIH HHS; NS43945
Buttini M, Yu GQ, Shockley K, Huang Y, Jones B, Masliah E, Mallory M, Yeo T, Longo FM, Mucke L	Modulation of Alzheimer-like synaptic and cholinergic deficits in transgenic mice by human apolipoprotein E depends on isoform, aging, and overexpression of amyloid beta peptides but not on plaque formation.	J. Neurosci.	22:24:10539-48	2002	12486146		Manuel Buttini, Gui-Qiu Yu, Kristina Shockley, Yadong Huang, Brian Jones, Eliezer Masliah, Margaret Mallory, Tracy Yeo, Frank M Longo, Lennart Mucke	Manuel Buttini	Lennart Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NINDS NIH HHS; NS41787
Wyss-Coray T, Mucke L	Inflammation in neurodegenerative disease--a double-edged sword.	Neuron	35:3:419-32	2002	12165466		Tony Wyss-Coray, Lennart Mucke	Tony Wyss-Coray	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California-San Francisco, San Francisco, CA 94141, USA. twysscoray@gladstone.ucsf.edu	NINDS NIH HHS; NS 43945
Raber J, Bongers G, LeFevour A, Buttini M, Mucke L	Androgens protect against apolipoprotein E4-induced cognitive deficits.	J. Neurosci.	22:12:5204-9	2002	12077215		Jacob Raber, Gerold Bongers, Anthony LeFevour, Manuel Buttini, Lennart Mucke	Jacob Raber	Lennart Mucke	Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, California 94141, USA. raberj@ohsu.edu	NIA NIH HHS; AG11385
Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L	beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease.	Proc. Natl. Acad. Sci. U.S.A.	98:21:12245-50	2001	11572944		E Masliah, E Rockenstein, I Veinbergs, Y Sagara, M Mallory, M Hashimoto, L Mucke	E Masliah	L Mucke	Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA. emasliah@ucsd.edu	NIA NIH HHS; AG5131
Wyss-Coray T, Lin C, Yan F, Yu GQ, Rohde M, McConlogue L, Masliah E, Mucke L	TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.	Nat. Med.	7:5:612-8	2001	11329064		T Wyss-Coray, C Lin, F Yan, G Q Yu, M Rohde, L McConlogue, E Masliah, L Mucke	T Wyss-Coray	L Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California, USA. twysscoray@gladstone.ucsf.edu	NIA NIH HHS; AG-51131
Mucke L, Yu GQ, McConlogue L, Rockenstein EM, Abraham CR, Masliah E	Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice.	Am. J. Pathol.	157:6:2003-10	2000	11106573		L Mucke, G Q Yu, L McConlogue, E M Rockenstein, C R Abraham, E Masliah	L Mucke	E Masliah	Gladstone Institute of Neurological Disease, Department of Neurology, and Neuroscience Program, University of California San Francisco, San Francisco, California, USA. Lmucke@gladstone.ucsf.edu	NIA NIH HHS; AG5131
Wyss-Coray T, Mucke L	Ibuprofen, inflammation and Alzheimer disease.	Nat. Med.	6:9:973-4	2000	10973311		T Wyss-Coray, L Mucke	T Wyss-Coray	L Mucke		NA
Mucke L, Masliah E, Yu GQ, Mallory M, Rockenstein EM, Tatsuno G, Hu K, Kholodenko D, Johnson-Wood K, McConlogue L	High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation.	J. Neurosci.	20:11:4050-8	2000	10818140		L Mucke, E Masliah, G Q Yu, M Mallory, E M Rockenstein, G Tatsuno, K Hu, D Kholodenko, K Johnson-Wood, L McConlogue	L Mucke	L McConlogue	Gladstone Institute of Neurological Disease, Department of Neurology, and Neuroscience Program, University of California, San Francisco, California 94141-9100, USA. lmucke@gladstone.ucsf.edu	NIA NIH HHS; AG5131
Wyss-Coray T, Lin C, von Euw D, Masliah E, Mucke L, Lacombe P	Alzheimer's disease-like cerebrovascular pathology in transforming growth factor-beta 1 transgenic mice and functional metabolic correlates.	Ann. N. Y. Acad. Sci.	903:317-23	2000	10818521		T Wyss-Coray, C Lin, D von Euw, E Masliah, L Mucke, P Lacombe	T Wyss-Coray	P Lacombe	Gladstone Institute of Neurological Disease, University of California, San Francisco 94141, USA. twysscoray@gladstone.ucsf.edu	NIA NIH HHS; AG11385
Raber J, Wong D, Yu GQ, Buttini M, Mahley RW, Pitas RE, Mucke L	Apolipoprotein E and cognitive performance.	Nature	404:6776:352-4	2000	10746713		J Raber, D Wong, G Q Yu, M Buttini, R W Mahley, R E Pitas, L Mucke	J Raber	L Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco 94141-9100, USA. jraber@gladstone.ucsf.edu	NA
Raber J, Akana SF, Bhatnagar S, Dallman MF, Wong D, Mucke L	Hypothalamic-pituitary-adrenal dysfunction in Apoe(-/-) mice: possible role in behavioral and metabolic alterations.	J. Neurosci.	20:5:2064-71	2000	10684907		J Raber, S F Akana, S Bhatnagar, M F Dallman, D Wong, L Mucke	J Raber	L Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA. jraber@gladstone.ucsf.edu	NIMH NIH HHS; MH057967
Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, Takeda A, Sagara Y, Sisk A, Mucke L	Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders.	Science	287:5456:1265-9	2000	10678833		E Masliah, E Rockenstein, I Veinbergs, M Mallory, M Hashimoto, A Takeda, Y Sagara, A Sisk, L Mucke	E Masliah	L Mucke	Department of Neurosciences, Department of Pathology, University of California San Diego, La Jolla, CA 92093-0624, USA. emasliah@ucsd.edu	NIA NIH HHS; AG5131
Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E	Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic mice.	Am. J. Pathol.	156:1:139-50	2000	10623661		T Wyss-Coray, C Lin, D A Sanan, L Mucke, E Masliah	T Wyss-Coray	E Masliah	Gladstone Institute of Neurological Disease, San Francisco, California 94141-9100, USA. twysscoray@gladstone.ucsf.edu	NIA NIH HHS; AG5131
Buttini M, Akeefe H, Lin C, Mahley RW, Pitas RE, Wyss-Coray T, Mucke L	Dominant negative effects of apolipoprotein E4 revealed in transgenic models of neurodegenerative disease.	Neuroscience	97:2:207-10	2000	10799751		M Buttini, H Akeefe, C Lin, R W Mahley, R E Pitas, T Wyss-Coray, L Mucke	M Buttini	L Mucke	Gladstone Institute of Neurological Disease University of California, P.O. Box 41900, San Francisco, CA 94141-9100, USA.	NA
D'hooge R, Franck F, Mucke L, De Deyn PP	Age-related behavioural deficits in transgenic mice expressing the HIV-1 coat protein gp120.	Eur. J. Neurosci.	11:12:4398-402	1999	10594667		R D'hooge, F Franck, L Mucke, P P De Deyn	R D'hooge	P P De Deyn	Laboratory of Neurochemistry and Behaviour, Born-Bunge Foundation, University of Antwerp, Belgium.	NIH HHS; NH58164
Huang F, Buttini M, Wyss-Coray T, McConlogue L, Kodama T, Pitas RE, Mucke L	Elimination of the class A scavenger receptor does not affect amyloid plaque formation or neurodegeneration in transgenic mice expressing human amyloid protein precursors.	Am. J. Pathol.	155:5:1741-7	1999	10550330		F Huang, M Buttini, T Wyss-Coray, L McConlogue, T Kodama, R E Pitas, L Mucke	F Huang	L Mucke	Gladstone Institute of Neurological Disease, Department of Neurology, University of California, San Francisco, USA.	NIA NIH HHS; AG11385
Xu X, Yang D, Wyss-Coray T, Yan J, Gan L, Sun Y, Mucke L	Wild-type but not Alzheimer-mutant amyloid precursor protein confers resistance against p53-mediated apoptosis.	Proc. Natl. Acad. Sci. U.S.A.	96:13:7547-52	1999	10377452		X Xu, D Yang, T Wyss-Coray, J Yan, L Gan, Y Sun, L Mucke	X Xu	L Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141-9100, USA.	NINDS NIH HHS; NS07067
Buttini M, Orth M, Bellosta S, Akeefe H, Pitas RE, Wyss-Coray T, Mucke L, Mahley RW	Expression of human apolipoprotein E3 or E4 in the brains of Apoe-/- mice: isoform-specific effects on neurodegeneration.	J. Neurosci.	19:12:4867-80	1999	10366621		M Buttini, M Orth, S Bellosta, H Akeefe, R E Pitas, T Wyss-Coray, L Mucke, R W Mahley	M Buttini	R W Mahley	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NA
Bush TG, Puvanachandra N, Horner CH, Polito A, Ostenfeld T, Svendsen CN, Mucke L, Johnson MH, Sofroniew MV	Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice.	Neuron	23:2:297-308	1999	10399936		T G Bush, N Puvanachandra, C H Horner, A Polito, T Ostenfeld, C N Svendsen, L Mucke, M H Johnson, M V Sofroniew	T G Bush	M V Sofroniew	Medical Research Council Cambridge Centre for Brain Repair, and Department of Anatomy, University of Cambridge, United Kingdom.	Wellcome Trust; 
Hsia AY, Masliah E, McConlogue L, Yu GQ, Tatsuno G, Hu K, Kholodenko D, Malenka RC, Nicoll RA, Mucke L	Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models.	Proc. Natl. Acad. Sci. U.S.A.	96:6:3228-33	1999	10077666		A Y Hsia, E Masliah, L McConlogue, G Q Yu, G Tatsuno, K Hu, D Kholodenko, R C Malenka, R A Nicoll, L Mucke	A Y Hsia	L Mucke	Department of Cellular and Molecular Pharmacology, University of California at San Francisco, San Francisco, CA 94143-0450, USA.	NA
Raber J, Wong D, Buttini M, Orth M, Bellosta S, Pitas RE, Mahley RW, Mucke L	Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females.	Proc. Natl. Acad. Sci. U.S.A.	95:18:10914-9	1998	9724804		J Raber, D Wong, M Buttini, M Orth, S Bellosta, R E Pitas, R W Mahley, L Mucke	J Raber	L Mucke	Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141-9100, USA. jraber@gladstone.ucsf.edu	NA
Masliah E, Raber J, Alford M, Mallory M, Mattson MP, Yang D, Wong D, Mucke L	Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis.	J. Biol. Chem.	273:20:12548-54	1998	9575214		E Masliah, J Raber, M Alford, M Mallory, M P Mattson, D Yang, D Wong, L Mucke	E Masliah	L Mucke	Departments of Neurosciences and Pathology, University of California San Diego, La Jolla, California 92093-0624, USA.	NINDS NIH HHS; NS34602
Bush TG, Savidge TC, Freeman TC, Cox HJ, Campbell EA, Mucke L, Johnson MH, Sofroniew MV	Fulminant jejuno-ileitis following ablation of enteric glia in adult transgenic mice.	Cell	93:2:189-201	1998	9568712		T G Bush, T C Savidge, T C Freeman, H J Cox, E A Campbell, L Mucke, M H Johnson, M V Sofroniew	T G Bush	M V Sofroniew	Medical Research Council Cambridge Centre for Brain Repair, Department of Anatomy, University of Cambridge, United Kingdom.	Wellcome Trust; 
Krucker T, Toggas SM, Mucke L, Siggins GR	Transgenic mice with cerebral expression of human immunodeficiency virus type-1 coat protein gp120 show divergent changes in short- and long-term potentiation in CA1 hippocampus.	Neuroscience	83:3:691-700	1998	9483553		T Krucker, S M Toggas, L Mucke, G R Siggins	T Krucker	G R Siggins	Scripps Research Institute and AIDS Research Center, Department of Neuropharmacology, La Jolla, CA 92037, USA.	NINDS NIH HHS; NS34602
Buttini M, Westland CE, Masliah E, Yafeh AM, Wyss-Coray T, Mucke L	Novel role of human CD4 molecule identified in neurodegeneration.	Nat. Med.	4:4:441-6	1998	9546790		M Buttini, C E Westland, E Masliah, A M Yafeh, T Wyss-Coray, L Mucke	M Buttini	L Mucke	Department of Neurology, University of California, San Francisco 94141-9100, USA.	NINDS NIH HHS; NS34602
Xu X, Raber J, Yang D, Su B, Mucke L	Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli.	Proc. Natl. Acad. Sci. U.S.A.	94:23:12655-60	1997	9356505		X Xu, J Raber, D Yang, B Su, L Mucke	X Xu	L Mucke	Gladstone Molecular Neurobiology Program and Department of Neurology, University of California, San Francisco, CA 94141, USA. xiao_xu@quickmail.ucsf.edu	NIA NIH HHS; AG11385
Raeber AJ, Race RE, Brandner S, Priola SA, Sailer A, Bessen RA, Mucke L, Manson J, Aguzzi A, Oldstone MB, Weissmann C, Chesebro B	Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie.	EMBO J.	16:20:6057-65	1997	9321385		A J Raeber, R E Race, S Brandner, S A Priola, A Sailer, R A Bessen, L Mucke, J Manson, A Aguzzi, M B Oldstone, C Weissmann, B Chesebro	A J Raeber	B Chesebro	Institut für Molekularbiologie, Abteilung I, University of Zürich, H-onggerberg, 8093 Z-urich, Switzerland.	NIA NIH HHS; AG04342
Wyss-Coray T, Masliah E, Mallory M, McConlogue L, Johnson-Wood K, Lin C, Mucke L	Amyloidogenic role of cytokine TGF-beta1 in transgenic mice and in Alzheimer's disease.	Nature	389:6651:603-6	1997	9335500		T Wyss-Coray, E Masliah, M Mallory, L McConlogue, K Johnson-Wood, C Lin, L Mucke	T Wyss-Coray	L Mucke	Gladstone Molecular Neurobiology Program and Department of Neurology, University of California, San Francisco 94141-9100, USA. Tony_Wyss@quickmail.ucsf.edu	NA
Wyss-Coray T, Borrow P, Brooker MJ, Mucke L	Astroglial overproduction of TGF-beta 1 enhances inflammatory central nervous system disease in transgenic mice .	J. Neuroimmunol.	77:1:45-50	1997	9209267		T Wyss-Coray, P Borrow, M J Brooker, L Mucke	T Wyss-Coray	L Mucke	Gladstone Molecular Neurobiology Program, University of California San Francisco 94141, USA. tony_wyss@quickmail.ucsf.edu	NIAID NIH HHS; AI37430-02
Raber J, Chen S, Mucke L, Feng L	Corticotropin-releasing factor and adrenocorticotrophic hormone as potential central mediators of OB effects.	J. Biol. Chem.	272:24:15057-60	1997	9182522		J Raber, S Chen, L Mucke, L Feng	J Raber	L Feng	Gladstone Molecular Neurobiology Program and the Department of Neurology, University of California, San Francisco, California 94141-9100, USA. Jacob_Raber@quickmail.ucsf.edu	NIDDK NIH HHS; DK49832-01A2
Masliah E, Westland CE, Rockenstein EM, Abraham CR, Mallory M, Veinberg I, Sheldon E, Mucke L	Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo.	Neuroscience	78:1:135-46	1997	9135095		E Masliah, C E Westland, E M Rockenstein, C R Abraham, M Mallory, I Veinberg, E Sheldon, L Mucke	E Masliah	L Mucke	Department of Neurosciences, University of California at San Diego, La Jolla 92093-0624, U.S.A.	NINDS NIH HHS; NS34602
Mattson MP, Barger SW, Furukawa K, Bruce AJ, Wyss-Coray T, Mark RJ, Mucke L	Cellular signaling roles of TGF beta, TNF alpha and beta APP in brain injury responses and Alzheimer's disease.	Brain Res. Brain Res. Rev.	23:1-2:47-61	1997	9063586		M P Mattson, S W Barger, K Furukawa, A J Bruce, T Wyss-Coray, R J Mark, L Mucke	M P Mattson	L Mucke	Sanders-Brown Research Center on Aging, University of Kentucky, Lexington 40536-0230, USA. mmattson@aging.coa.uky.edu	NINDS NIH HHS; NS30583
Raber J, Toggas SM, Lee S, Bloom FE, Epstein CJ, Mucke L	Central nervous system expression of HIV-1 Gp120 activates the hypothalamic-pituitary-adrenal axis: evidence for involvement of NMDA receptors and nitric oxide synthase.	Virology	226:2:362-73	1996	8955056		J Raber, S M Toggas, S Lee, F E Bloom, C J Epstein, L Mucke	J Raber	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA.	NINDS NIH HHS; NS34602
Zhao J, Paganini L, Mucke L, Gordon M, Refolo L, Carman M, Sinha S, Oltersdorf T, Lieberburg I, McConlogue L	Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes.	J. Biol. Chem.	271:49:31407-11	1996	8940150		J Zhao, L Paganini, L Mucke, M Gordon, L Refolo, M Carman, S Sinha, T Oltersdorf, I Lieberburg, L McConlogue	J Zhao	L McConlogue	Athena Neurosciences, Inc., South San Francisco, California 94080, USA. amyloid!lisam@uunet.uu.net	NIA NIH HHS; AG11385
D'Hooge R, Nagels G, Westland CE, Mucke L, De Deyn PP	Spatial learning deficit in mice expressing human 751-amino acid beta-amyloid precursor protein.	Neuroreport	7:15-17:2807-11	1996	8981472		R D'Hooge, G Nagels, C E Westland, L Mucke, P P De Deyn	R D'Hooge	P P De Deyn	Laboratory of Neurochemistry and Behaviour, Born-Bunge Foundation, Antwerp, Belgium.	NIA NIH HHS; AG11385
Masliah E, Sisk A, Mallory M, Mucke L, Schenk D, Games D	Comparison of neurodegenerative pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein and Alzheimer's disease.	J. Neurosci.	16:18:5795-811	1996	8795633		E Masliah, A Sisk, M Mallory, L Mucke, D Schenk, D Games	E Masliah	D Games	Department of Neurosciences, University of California-San Diego, La Jolla 92093-0624, USA.	NIA NIH HHS; AG5131
Mohajeri MH, Bartsch U, van der Putten H, Sansig G, Mucke L, Schachner M	Neurite outgrowth on non-permissive substrates in vitro is enhanced by ectopic expression of the neural adhesion molecule L1 by mouse astrocytes.	Eur. J. Neurosci.	8:6:1085-97	1996	8752578		M H Mohajeri, U Bartsch, H van der Putten, G Sansig, L Mucke, M Schachner	M H Mohajeri	M Schachner	Department of Nerobiology, Swiss Federal Institute fo Technology, Honggerberg, 8093 Zurich, Switzerland.	NA
Wyss-Coray T, Masliah E, Toggas SM, Rockenstein EM, Brooker MJ, Lee HS, Mucke L	Dysregulation of signal transduction pathways as a potential mechanism of nervous system alterations in HIV-1 gp120 transgenic mice and humans with HIV-1 encephalitis.	J. Clin. Invest.	97:3:789-98	1996	8609236		T Wyss-Coray, E Masliah, S M Toggas, E M Rockenstein, M J Brooker, H S Lee, L Mucke	T Wyss-Coray	L Mucke	Gladstone Molecular Neurobiology Program, University of California, San Francisco 94141-9100, USA.	NINDS NIH HHS; NS33056
Mucke L, Abraham CR, Masliah E	Neurotrophic and neuroprotective effects of hAPP in transgenic mice.	Ann. N. Y. Acad. Sci.	777:82-8	1996	8624131		L Mucke, C R Abraham, E Masliah	L Mucke	E Masliah	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA. lmucke@scripps.edu	NIMH NIH HHS; MH-47680
Toggas SM, Masliah E, Mucke L	Prevention of HIV-1 gp120-induced neuronal damage in the central nervous system of transgenic mice by the NMDA receptor antagonist memantine.	Brain Res.	706:2:303-7	1996	8822372		S M Toggas, E Masliah, L Mucke	S M Toggas	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.	NINDS NIH HHS; NS33056
Masliah E, Ge N, Mucke L	Pathogenesis of HIV-1 associated neurodegeneration.	Crit Rev Neurobiol	10:1:57-67	1996	8853954		E Masliah, N Ge, L Mucke	E Masliah	L Mucke	Department of Neurosciences, University of California, San Diego, La Jolla 92093-0624, USA.	NINDS NIH HHS; NS33056
Toggas SM, Mucke L	Transgenic models in the study of AIDS dementia complex.	Curr. Top. Microbiol. Immunol.	206:223-41	1996	8608719		S M Toggas, L Mucke	S M Toggas	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.	NINDS NIH HHS; NS-34602
Rockenstein EM, McConlogue L, Tan H, Power M, Masliah E, Mucke L	Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.	J. Biol. Chem.	270:47:28257-67	1995	7499323		E M Rockenstein, L McConlogue, H Tan, M Power, E Masliah, L Mucke	E M Rockenstein	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA.	NCRR NIH HHS; M01 RR00833
Rall GF, Mucke L, Oldstone MB	Consequences of cytotoxic T lymphocyte interaction with major histocompatibility complex class I-expressing neurons in vivo.	J. Exp. Med.	182:5:1201-12	1995	7595191		G F Rall, L Mucke, M B Oldstone	G F Rall	M B Oldstone	Scripps Research Institute, Department of Neuropharmacology, La Jolla, California 92037, USA.	NINDS NIH HHS; NS12428
Race RE, Priola SA, Bessen RA, Ernst D, Dockter J, Rall GF, Mucke L, Chesebro B, Oldstone MB	Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent.	Neuron	15:5:1183-91	1995	7576660		R E Race, S A Priola, R A Bessen, D Ernst, J Dockter, G F Rall, L Mucke, B Chesebro, M B Oldstone	R E Race	M B Oldstone	Laboratory of Persistent Viral Diseases, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840, USA.	NA
Borrow P, Cornell JL, Ruppe MD, Mucke L	Immunization-induced inflammatory infiltration of the central nervous system in transgenic mice expressing a microbial antigen in astrocytes.	J. Neuroimmunol.	61:2:133-49	1995	7593549		P Borrow, J L Cornell, M D Ruppe, L Mucke	P Borrow	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.	NINDS NIH HHS; NS33056
Wyss-Coray T, Feng L, Masliah E, Ruppe MD, Lee HS, Toggas SM, Rockenstein EM, Mucke L	Increased central nervous system production of extracellular matrix components and development of hydrocephalus in transgenic mice overexpressing transforming growth factor-beta 1.	Am. J. Pathol.	147:1:53-67	1995	7604885		T Wyss-Coray, L Feng, E Masliah, M D Ruppe, H S Lee, S M Toggas, E M Rockenstein, L Mucke	T Wyss-Coray	L Mucke	Department of Neuropharmacology, Scripps Research Institute, California, USA.	NIA NIH HHS; AG-11385
Verderber L, Johnson W, Mucke L, Sarthy V	Differential regulation of a glial fibrillary acidic protein-LacZ transgene in retinal astrocytes and Müller cells.	Invest. Ophthalmol. Vis. Sci.	36:6:1137-43	1995	7730023		L Verderber, W Johnson, L Mucke, V Sarthy	L Verderber	V Sarthy	Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois 60611, USA.	NIMH NIH HHS; MH47680
Mucke L, Abraham CR, Ruppe MD, Rockenstein EM, Toggas SM, Mallory M, Alford M, Masliah E	Protection against HIV-1 gp120-induced brain damage by neuronal expression of human amyloid precursor protein.	J. Exp. Med.	181:4:1551-6	1995	7699335		L Mucke, C R Abraham, M D Ruppe, E M Rockenstein, S M Toggas, M Mallory, M Alford, E Masliah	L Mucke	E Masliah	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA.	NIMH NIH HHS; MH-47680
Lipton SA, Brenneman DE, Silverstein FS, Masliah E, Mucke L	gp120 and neurotoxicity in vivo.	Trends Pharmacol. Sci.	16:4:122	1995	7610496		S A Lipton, D E Brenneman, F S Silverstein, E Masliah, L Mucke	S A Lipton	L Mucke		NA
Johnson WB, Ruppe MD, Rockenstein EM, Price J, Sarthy VP, Verderber LC, Mucke L	Indicator expression directed by regulatory sequences of the glial fibrillary acidic protein (GFAP) gene: in vivo comparison of distinct GFAP-lacZ transgenes.	Glia	13:3:174-84	1995	7782103		W B Johnson, M D Ruppe, E M Rockenstein, J Price, V P Sarthy, L C Verderber, L Mucke	W B Johnson	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037, USA.	NIMH NIH HHS; MH47680
Mucke L, Masliah E, Campbell IL	Transgenic models to assess the neuropathogenic potential of HIV-1 proteins and cytokines.	Curr. Top. Microbiol. Immunol.	202:187-205	1995	7587363		L Mucke, E Masliah, I L Campbell	L Mucke	I L Campbell	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037, USA.	NIMH NIH HHS; MH-47680
Mucke L, Masliah E, Johnson WB, Ruppe MD, Alford M, Rockenstein EM, Forss-Petter S, Pietropaolo M, Mallory M, Abraham CR	Synaptotrophic effects of human amyloid beta protein precursors in the cortex of transgenic mice.	Brain Res.	666:2:151-67	1994	7882025		L Mucke, E Masliah, W B Johnson, M D Ruppe, M Alford, E M Rockenstein, S Forss-Petter, M Pietropaolo, M Mallory, C R Abraham	L Mucke	C R Abraham	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.	NIA NIH HHS; AG-11385
Rall GF, Mucke L, Nerenberg M, Oldstone MB	A transgenic mouse model to assess the interaction of cytotoxic T lymphocytes with virally infected, class I MHC-expressing astrocytes.	J. Neuroimmunol.	52:1:61-8	1994	8207120		G F Rall, L Mucke, M Nerenberg, M B Oldstone	G F Rall	M B Oldstone	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.	NINDS NIH HHS; NS12428
Toggas SM, Masliah E, Rockenstein EM, Rall GF, Abraham CR, Mucke L	Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice.	Nature	367:6459:188-93	1994	8114918		S M Toggas, E Masliah, E M Rockenstein, G F Rall, C R Abraham, L Mucke	S M Toggas	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037.	NA
Campbell IL, Abraham CR, Masliah E, Kemper P, Inglis JD, Oldstone MB, Mucke L	Neurologic disease induced in transgenic mice by cerebral overexpression of interleukin 6.	Proc. Natl. Acad. Sci. U.S.A.	90:21:10061-5	1993	7694279		I L Campbell, C R Abraham, E Masliah, P Kemper, J D Inglis, M B Oldstone, L Mucke	I L Campbell	L Mucke	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.	NIMH NIH HHS; MH50426-01
Mucke L, Eddleston M	Astrocytes in infectious and immune-mediated diseases of the central nervous system.	FASEB J.	7:13:1226-32	1993	8405808		L Mucke, M Eddleston	L Mucke	M Eddleston	Department of Neuropharmacology, Scripps Research Institute, La Jolla, California 92037.	NIMH NIH HHS; MH47680
Abraham CR, Kanemaru K, Mucke L	Expression of cathepsin G-like and alpha 1-antichymotrypsin-like proteins in reactive astrocytes.	Brain Res.	621:2:222-32	1993	8242336		C R Abraham, K Kanemaru, L Mucke	C R Abraham	L Mucke	Department of Biochemistry, Boston University School of Medicine, MA 02118-2394.	NIMH NIH HHS; MH47680
Eddleston M, Mucke L	Molecular profile of reactive astrocytes--implications for their role in neurologic disease.	Neuroscience	54:1:15-36	1993	8515840		M Eddleston, L Mucke	M Eddleston	L Mucke	Department of Neuropharmacology, Scripps Research Institute.	NIMH NIH HHS; MHA47680
Abraham CR, Razzaboni BL, Papastoitsis G, Picard E, Kanemaru K, Meckelein B, Mucke L	Purification and cloning of brain proteases capable of degrading the beta-amyloid precursor protein.	Ann. N. Y. Acad. Sci.	674:174-9	1992	1288362		C R Abraham, B L Razzaboni, G Papastoitsis, E Picard, K Kanemaru, B Meckelein, L Mucke	C R Abraham	L Mucke	Arthritis Center, Boston University School of Medicine, Massachusetts 02118.	NIA NIH HHS; AG-09905
Mucke L, Oldstone MB	The expression of major histocompatibility complex (MHC) class I antigens in the brain differs markedly in acute and persistent infections with lymphocytic choriomeningitis virus (LCMV).	J. Neuroimmunol.	36:2-3:193-8	1992	1732281		L Mucke, M B Oldstone	L Mucke	M B Oldstone	Department of Neuropharmacology, Scripps Research Institute, La Jolla, CA 92037.	NIMH NIH HHS; P50-MHA47680-01
Joly E, Mucke L, Oldstone MB	Viral persistence in neurons explained by lack of major histocompatibility class I expression.	Science	253:5025:1283-5	1991	1891717		E Joly, L Mucke, M B Oldstone	E Joly	M B Oldstone	Department of Neuropharmacology, Scripps Clinic and Research Foundation, La Jolla, CA 92037.	NA
Mucke L, Oldstone MB, Morris JC, Nerenberg MI	Rapid activation of astrocyte-specific expression of GFAP-lacZ transgene by focal injury.	New Biol.	3:5:465-74	1991	1883812		L Mucke, M B Oldstone, J C Morris, M I Nerenberg	L Mucke	M I Nerenberg	Department of Neuropharmacology, Research Institute of Scripps Clinic, La Jolla, CA 92037.	NINDS NIH HHS; NS12428
Ross ME, Evinger MJ, Hyman SE, Carroll JM, Mucke L, Comb M, Reis DJ, Joh TH, Goodman HM	Identification of a functional glucocorticoid response element in the phenylethanolamine N-methyltransferase promoter using fusion genes introduced into chromaffin cells in primary culture.	J. Neurosci.	10:2:520-30	1990	2303857		M E Ross, M J Evinger, S E Hyman, J M Carroll, L Mucke, M Comb, D J Reis, T H Joh, H M Goodman	M E Ross	H M Goodman	Department of Molecular Biology, Massachusetts General Hospital, Boston 02114.	NIDDK NIH HHS; DK01410-04
Berger JR, Mucke L	Prolonged survival and partial recovery in AIDS-associated progressive multifocal leukoencephalopathy.	Neurology	38:7:1060-5	1988	3386823		J R Berger, L Mucke	J R Berger	L Mucke	Department of Neurology, University of Miami School of Medicine, FL 33136.	NA
Benedek G, Mucke L, Norita M, Albowitz B, Creutzfeldt OD	Anterior ectosylvian visual area (AEV) of the cat: physiological properties.	Prog. Brain Res.	75:245-55	1988	3187054		G Benedek, L Mucke, M Norita, B Albowitz, O D Creutzfeldt	G Benedek	O D Creutzfeldt		NA
Schalling M, Dagerlind A, Brene S, Petterson R, Kvist S, Brownstein M, Hyman SE, Mucke L, Goodman HM, Joh TH	Localization of mRNA for phenylethanolamine N-methyltransferase (PNMT) using in situ hybridization.	Acta Physiol. Scand.	131:4:631-2	1987	3442246		M Schalling, A Dagerlind, S Brene, R Petterson, S Kvist, M Brownstein, S E Hyman, L Mucke, H M Goodman, T H Joh	M Schalling	T H Joh	Department of Histology, Karolinska Institutet, Stockholm, Sweden.	NA
Mucke L, Maciewicz R	Clinical management of neuropathic pain.	Neurol Clin	5:4:649-63	1987	2828905		L Mucke, R Maciewicz	L Mucke	R Maciewicz	Neurology Service, Massachusetts General Hospital, Boston.	NA
Norita M, Mucke L, Benedek G, Albowitz B, Katoh Y, Creutzfeldt OD	Connections of the anterior ectosylvian visual area (AEV).	Exp Brain Res	62:2:225-40	1986	3709710		M Norita, L Mucke, G Benedek, B Albowitz, Y Katoh, O D Creutzfeldt	M Norita	O D Creutzfeldt		NA
Mucke L, Norita M, Benedek G, Creutzfeldt O	Physiologic and anatomic investigation of a visual cortical area situated in the ventral bank of the anterior ectosylvian sulcus of the cat.	Exp Brain Res	46:1:1-11	1982	7067781		L Mucke, M Norita, G Benedek, O Creutzfeldt	L Mucke	O Creutzfeldt		NA
Kumar A, Möcklinghoff S, Yumoto F, Jaroszewski L, Farr CL, Grzechnik A, Nguyen P, Weichenberger CX, Chiu HJ, Klock HE, Elsliger MA, Deacon AM, Godzik A, Lesley SA, Conklin BR, Fletterick RJ, Wilson IA	Structure of a novel winged-helix like domain from human NFRKB protein.	PLoS ONE	7:9:e43761	2012	22984442		Abhinav Kumar, Sabine Möcklinghoff, Fumiaki Yumoto, Lukasz Jaroszewski, Carol L Farr, Anna Grzechnik, Phuong Nguyen, Christian X Weichenberger, Hsiu-Ju Chiu, Heath E Klock, Marc-André Elsliger, Ashley M Deacon, Adam Godzik, Scott A Lesley, Bruce R Conklin, Robert J Fletterick, Ian A Wilson	Abhinav Kumar	Ian A Wilson	Joint Center for Structural Genomics, La Jolla, California, United States of America.	NIGMS NIH HHS; U54 GM094586
Zambon AC, Gaj S, Ho I, Hanspers K, Vranizan K, Evelo CT, Conklin BR, Pico AR, Salomonis N	GO-Elite: a flexible solution for pathway and ontology over-representation.	Bioinformatics	28:16:2209-10	2012	22743224		Alexander C Zambon, Stan Gaj, Isaac Ho, Kristina Hanspers, Karen Vranizan, Chris T Evelo, Bruce R Conklin, Alexander R Pico, Nathan Salomonis	Alexander C Zambon	Nathan Salomonis	Departments of Pharmacology and Medicine, University of California at San Diego, La Jolla, CA 92093, USA.	NHLBI NIH HHS; U01 HL100406
Kelder T, van Iersel MP, Hanspers K, Kutmon M, Conklin BR, Evelo CT, Pico AR	WikiPathways: building research communities on biological pathways.	Nucleic Acids Res.	40:Database issue:D1301-7	2012	22096230		Thomas Kelder, Martijn P van Iersel, Kristina Hanspers, Martina Kutmon, Bruce R Conklin, Chris T Evelo, Alexander R Pico	Thomas Kelder	Alexander R Pico	Department of Bioinformatics-BiGCaT, Maastricht University, Maastricht, The Netherlands. thomaskelder@gmail.com	NHLBI NIH HHS; U01 HL100406
Lahti AL, Kujala VJ, Chapman H, Koivisto AP, Pekkanen-Mattila M, Kerkelä E, Hyttinen J, Kontula K, Swan H, Conklin BR, Yamanaka S, Silvennoinen O, Aalto-Setälä K	Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture.	Dis Model Mech	5:2:220-30	2012	22052944		Anna L Lahti, Ville J Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkelä, Jari Hyttinen, Kimmo Kontula, Heikki Swan, Bruce R Conklin, Shinya Yamanaka, Olli Silvennoinen, Katriina Aalto-Setälä	Anna L Lahti	Katriina Aalto-Setälä	Institute of Biomedical Technology, University of Tampere, Tampere, Finland.	NHLBI NIH HHS; U01 HL100406
Kazakia GJ, Speer D, Shanbhag S, Majumdar S, Conklin BR, Nissenson RA, Hsiao EC	Mineral composition is altered by osteoblast expression of an engineered G(s)-coupled receptor.	Calcif. Tissue Int.	89:1:10-20	2011	21526395		G J Kazakia, D Speer, S Shanbhag, S Majumdar, B R Conklin, R A Nissenson, E C Hsiao	G J Kazakia	E C Hsiao	Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94107, USA. galateia.kazakia@ucsf.edu	NCRR NIH HHS; RR18928-01
Millard SM, Louie AM, Wattanachanya L, Wronski TJ, Conklin BR, Nissenson RA	Blockade of receptor-activated G(i) signaling in osteoblasts in vivo leads to site-specific increases in cortical and cancellous bone formation.	J. Bone Miner. Res.	26:4:822-32	2011	20939063		Susan M Millard, Alyssa M Louie, Lalita Wattanachanya, Thomas J Wronski, Bruce R Conklin, Robert A Nissenson	Susan M Millard	Robert A Nissenson	Endocrine Research Unit, Veterans Administration Medical Center, University of California San Francisco, San Francisco, CA 94121, USA.	NIDDK NIH HHS; DK072071
Hsiao EC, Nguyen TD, Ng JK, Scott MJ, Chang WC, Zahed H, Conklin BR	Constitutive Gs activation using a single-construct tetracycline-inducible expression system in embryonic stem cells and mice.	Stem Cell Res Ther	2:2:11	2011	21375737		Edward C Hsiao, Trieu D Nguyen, Jennifer K Ng, Mark J Scott, Wei Chun Chang, Hengameh Zahed, Bruce R Conklin	Edward C Hsiao	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, 1650 Owens St,, San Francisco, CA 94158, USA. edward.hsiao@ucsf.edu	NHLBI NIH HHS; U01 HL100406
Kelder T, Conklin BR, Evelo CT, Pico AR	Finding the right questions: exploratory pathway analysis to enhance biological discovery in large datasets.	PLoS Biol.	8:8:	2010	20824171		Thomas Kelder, Bruce R Conklin, Chris T Evelo, Alexander R Pico	Thomas Kelder	Alexander R Pico	Department of Bioinformatics, BiGCaT, Maastricht University, Maastricht, The Netherlands. thomaskelder@gmail.com	NIGMS NIH HHS; GM080223
Salomonis N, Conklin BR	Stem cell pluripotency: alternative modes of transcription regulation.	Cell Cycle	9:16:3133-4	2010	20814242		Nathan Salomonis, Bruce R Conklin	Nathan Salomonis	Bruce R Conklin		NA
Emig D, Salomonis N, Baumbach J, Lengauer T, Conklin BR, Albrecht M	AltAnalyze and DomainGraph: analyzing and visualizing exon expression data.	Nucleic Acids Res.	38:Web Server issue:W755-62	2010	20513647		Dorothea Emig, Nathan Salomonis, Jan Baumbach, Thomas Lengauer, Bruce R Conklin, Mario Albrecht	Dorothea Emig	Mario Albrecht	Max Planck Institute for Informatics, 66123 Saarbrücken, Germany. demig@mpi-inf.mpg.de	NHLBI NIH HHS; HL66621
Salomonis N, Schlieve CR, Pereira L, Wahlquist C, Colas A, Zambon AC, Vranizan K, Spindler MJ, Pico AR, Cline MS, Clark TA, Williams A, Blume JE, Samal E, Mercola M, Merrill BJ, Conklin BR	Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation.	Proc. Natl. Acad. Sci. U.S.A.	107:23:10514-9	2010	20498046		Nathan Salomonis, Christopher R Schlieve, Laura Pereira, Christine Wahlquist, Alexandre Colas, Alexander C Zambon, Karen Vranizan, Matthew J Spindler, Alexander R Pico, Melissa S Cline, Tyson A Clark, Alan Williams, John E Blume, Eva Samal, Mark Mercola, Bradley J Merrill, Bruce R Conklin	Nathan Salomonis	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NHLBI NIH HHS; U01 HL100406
Hsiao EC, Boudignon BM, Halloran BP, Nissenson RA, Conklin BR	Gs G protein-coupled receptor signaling in osteoblasts elicits age-dependent effects on bone formation.	J. Bone Miner. Res.	25:3:584-93	2010	20200944		Edward C Hsiao, Benjamin M Boudignon, Bernard P Halloran, Robert A Nissenson, Bruce R Conklin	Edward C Hsiao	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. ehsiao@Gladstone.ucsf.edu	NHLBI NIH HHS; U01 HL100406
Hsiao EC, Millard SM, Louie A, Huang Y, Conklin BR, Nissenson RA	Ligand-mediated activation of an engineered gs g protein-coupled receptor in osteoblasts increases trabecular bone formation.	Mol. Endocrinol.	24:3:621-31	2010	20150184		Edward C Hsiao, Susan M Millard, Alyssa Louie, Yong Huang, Bruce R Conklin, Robert A Nissenson	Edward C Hsiao	Robert A Nissenson	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, California 94158, USA. ehsiao@gladstone.ucsf.edu	NHLBI NIH HHS; U01 HL100406
Lo B, Parham L, Alvarez-Buylla A, Cedars M, Conklin B, Fisher S, Gates E, Giudice L, Halme DG, Hershon W, Kriegstein A, Kwok PY, Wagner R	Cloning mice and men: prohibiting the use of iPS cells for human reproductive cloning.	Cell Stem Cell	6:1:16-20	2010	20085739		Bernard Lo, Lindsay Parham, Arturo Alvarez-Buylla, Marcelle Cedars, Bruce Conklin, Susan Fisher, Elena Gates, Linda Giudice, Dina Gould Halme, William Hershon, Arnold Kriegstein, Pui-Yan Kwok, Richard Wagner	Bernard Lo	Richard Wagner	Program in Medical Ethics, Department of Medicine, The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, CA 94143, USA. bernie@medicine.ucsf.edu	NCRR NIH HHS; 1 UL1 RR024131-04
van Iersel MP, Pico AR, Kelder T, Gao J, Ho I, Hanspers K, Conklin BR, Evelo CT	The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services.	BMC Bioinformatics	11:5	2010	20047655		Martijn P van Iersel, Alexander R Pico, Thomas Kelder, Jianjiong Gao, Isaac Ho, Kristina Hanspers, Bruce R Conklin, Chris T Evelo	Martijn P van Iersel	Chris T Evelo	Department of Bioinformatics-BiGCaT, Maastricht University, Maastricht, the Netherlands. martijn.vaniersel@bigcat.unimaas.nl	NHGRI NIH HHS; HG003053
Nakamura K, Salomonis N, Tomoda K, Yamanaka S, Conklin BR	G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies.	PLoS ONE	4:11:e7780	2009	19936228		Kenta Nakamura, Nathan Salomonis, Kiichiro Tomoda, Shinya Yamanaka, Bruce R Conklin	Kenta Nakamura	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America. kenta.nakamura@ucsf.edu	NHLBI NIH HHS; U01 HL100406
Salomonis N, Nelson B, Vranizan K, Pico AR, Hanspers K, Kuchinsky A, Ta L, Mercola M, Conklin BR	Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors.	PLoS Comput. Biol.	5:11:e1000553	2009	19893621		Nathan Salomonis, Brandon Nelson, Karen Vranizan, Alexander R Pico, Kristina Hanspers, Allan Kuchinsky, Linda Ta, Mark Mercola, Bruce R Conklin	Nathan Salomonis	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America.	NHLBI NIH HHS; U01 HL100406
Lo B, Conklin BR	Consent: criteria should be drawn up for tissue donors.	Nature	461:7264:593	2009	19794473		Bernard Lo, Bruce R Conklin	Bernard Lo	Bruce R Conklin		NA
Conklin BR	Journal club. A geneticist wonders why we need to sleep.	Nature	461:7264:573	2009	19794457		Bruce R Conklin	Bruce R Conklin	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NA
Kelder T, Pico AR, Hanspers K, van Iersel MP, Evelo C, Conklin BR	Mining biological pathways using WikiPathways web services.	PLoS ONE	4:7:e6447	2009	19649250		Thomas Kelder, Alexander R Pico, Kristina Hanspers, Martijn P van Iersel, Chris Evelo, Bruce R Conklin	Thomas Kelder	Bruce R Conklin	Department of Bioinformatics - BiGCaT, Maastricht University, Maastricht, The Netherlands.	NHGRI NIH HHS; HG003053
Neumann SA, Tingley WG, Conklin BR, Shrader CJ, Peet E, Muldoon MF, Jennings JR, Ferrell RE, Manuck SB	AKAP10 (I646V) functional polymorphism predicts heart rate and heart rate variability in apparently healthy, middle-aged European-Americans.	Psychophysiology	46:3:466-72	2009	19496216		Serina A Neumann, Whittemore G Tingley, Bruce R Conklin, Catherine J Shrader, Eloise Peet, Matthew F Muldoon, J Richard Jennings, Robert E Ferrell, Stephen B Manuck	Serina A Neumann	Stephen B Manuck	Eastern Virginia Medical School, Norfolk, Virginia 23507, USA. neumansa@evms.edu	NHLBI NIH HHS; R01 HL065137
Kita-Matsuo H, Barcova M, Prigozhina N, Salomonis N, Wei K, Jacot JG, Nelson B, Spiering S, Haverslag R, Kim C, Talantova M, Bajpai R, Calzolari D, Terskikh A, McCulloch AD, Price JH, Conklin BR, Chen HS, Mercola M	Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes.	PLoS ONE	4:4:e5046	2009	19352491		Hiroko Kita-Matsuo, Maria Barcova, Natalie Prigozhina, Nathan Salomonis, Karen Wei, Jeffrey G Jacot, Brandon Nelson, Sean Spiering, René Haverslag, Changsung Kim, Maria Talantova, Ruchi Bajpai, Diego Calzolari, Alexey Terskikh, Andrew D McCulloch, Jeffrey H Price, Bruce R Conklin, H S Vincent Chen, Mark Mercola	Hiroko Kita-Matsuo	Mark Mercola	Burnham Institute for Medical Research, La Jolla, California, United States of America.	NHLBI NIH HHS; U01 HL100406
Aalto-Setälä K, Conklin BR, Lo B	Obtaining consent for future research with induced pluripotent cells: opportunities and challenges.	PLoS Biol.	7:2:e42	2009	19243222		Katriina Aalto-Setälä, Bruce R Conklin, Bernard Lo	Katriina Aalto-Setälä	Bernard Lo	Gladstone Institute of Cardiovascular Disease, San Francisco, CA, USA.	NCRR NIH HHS; 1 UL1-RR024131-01
Pico AR, Smirnov IV, Chang JS, Yeh RF, Wiemels JL, Wiencke JK, Tihan T, Conklin BR, Wrensch M	SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system.	Nucleic Acids Res.	37:Database issue:D803-9	2009	18984625		Alexander R Pico, Ivan V Smirnov, Jeffrey S Chang, Ru-Fang Yeh, Joseph L Wiemels, John K Wiencke, Tarik Tihan, Bruce R Conklin, Margaret Wrensch	Alexander R Pico	Margaret Wrensch	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA. apico@gladstone.ucsf.edu	NCI NIH HHS; R25 CA112355
van Iersel MP, Kelder T, Pico AR, Hanspers K, Coort S, Conklin BR, Evelo C	Presenting and exploring biological pathways with PathVisio.	BMC Bioinformatics	9:399	2008	18817533		Martijn P van Iersel, Thomas Kelder, Alexander R Pico, Kristina Hanspers, Susan Coort, Bruce R Conklin, Chris Evelo	Martijn P van Iersel	Chris Evelo	Department of Bioinformatics, BiGCaT Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, the Netherlands. martijn.vaniersel@bigcat.unimaas.nl	NHGRI NIH HHS; HG003053
Conklin BR, Hsiao EC, Claeysen S, Dumuis A, Srinivasan S, Forsayeth JR, Guettier JM, Chang WC, Pei Y, McCarthy KD, Nissenson RA, Wess J, Bockaert J, Roth BL	Engineering GPCR signaling pathways with RASSLs.	Nat. Methods	5:8:673-8	2008	18668035		Bruce R Conklin, Edward C Hsiao, Sylvie Claeysen, Aline Dumuis, Supriya Srinivasan, John R Forsayeth, Jean-Marc Guettier, W C Chang, Ying Pei, Ken D McCarthy, Robert A Nissenson, Jürgen Wess, Joël Bockaert, Bryan L Roth	Bruce R Conklin	Bryan L Roth	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, California 94158, USA. bconklin@gladstone.ucsf.edu	NIMH NIH HHS; U19MH82441
Pico AR, Kelder T, van Iersel MP, Hanspers K, Conklin BR, Evelo C	WikiPathways: pathway editing for the people.	PLoS Biol.	6:7:e184	2008	18651794		Alexander R Pico, Thomas Kelder, Martijn P van Iersel, Kristina Hanspers, Bruce R Conklin, Chris Evelo	Alexander R Pico	Chris Evelo	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NHGRI NIH HHS; HG003053
Hsiao EC, Yoshinaga Y, Nguyen TD, Musone SL, Kim JE, Swinton P, Espineda I, Manalac C, deJong PJ, Conklin BR	Marking embryonic stem cells with a 2A self-cleaving peptide: a NKX2-5 emerald GFP BAC reporter.	PLoS ONE	3:7:e2532	2008	18596956		Edward C Hsiao, Yuko Yoshinaga, Trieu D Nguyen, Stacy L Musone, Judy E Kim, Paul Swinton, Isidro Espineda, Carlota Manalac, Pieter J deJong, Bruce R Conklin	Edward C Hsiao	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America. ehsiao@gladstone.ucsf.edu	NCRR NIH HHS; RR18928-01
Hsiao EC, Boudignon BM, Chang WC, Bencsik M, Peng J, Nguyen TD, Manalac C, Halloran BP, Conklin BR, Nissenson RA	Osteoblast expression of an engineered Gs-coupled receptor dramatically increases bone mass.	Proc. Natl. Acad. Sci. U.S.A.	105:4:1209-14	2008	18212126		Edward C Hsiao, Benjamin M Boudignon, Wei C Chang, Margaret Bencsik, Jeffrey Peng, Trieu D Nguyen, Carlota Manalac, Bernard P Halloran, Bruce R Conklin, Robert A Nissenson	Edward C Hsiao	Robert A Nissenson	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. ehsiao@gladstone.ucsf.edu	NCRR NIH HHS; RR18928-01
Chang WC, Ng JK, Nguyen T, Pellissier L, Claeysen S, Hsiao EC, Conklin BR	Modifying ligand-induced and constitutive signaling of the human 5-HT4 receptor.	PLoS ONE	2:12:e1317	2007	18338032		Wei Chun Chang, Jennifer K Ng, Trieu Nguyen, Lucie Pellissier, Sylvie Claeysen, Edward C Hsiao, Bruce R Conklin	Wei Chun Chang	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, University of California at San Francisco, San Francisco, California, United States of America.	NHLBI NIH HHS; HL-60664
Peng J, Bencsik M, Louie A, Lu W, Millard S, Nguyen P, Burghardt A, Majumdar S, Wronski TJ, Halloran B, Conklin BR, Nissenson RA	Conditional expression of a Gi-coupled receptor in osteoblasts results in trabecular osteopenia.	Endocrinology	149:3:1329-37	2008	18048501		J Peng, M Bencsik, A Louie, W Lu, S Millard, P Nguyen, A Burghardt, S Majumdar, T J Wronski, B Halloran, B R Conklin, R A Nissenson	J Peng	R A Nissenson	Endocrine Research Unit, Veterans' Affairs Medical Center, and Department of Medicine, University of California, San Francisco, California 94121, USA.	NHLBI NIH HHS; HL60644
Zhang L, Zambon AC, Vranizan K, Pothula K, Conklin BR, Insel PA	Gene expression signatures of cAMP/protein kinase A (PKA)-promoted, mitochondrial-dependent apoptosis. Comparative analysis of wild-type and cAMP-deathless S49 lymphoma cells.	J. Biol. Chem.	283:7:4304-13	2008	18048352		Lingzhi Zhang, Alexander C Zambon, Karen Vranizan, Kanishka Pothula, Bruce R Conklin, Paul A Insel	Lingzhi Zhang	Paul A Insel	Department of Pharmacology, University of California San Diego, La Jolla, California 92093, USA.	NIGMS NIH HHS; GM61774
Srinivasan S, Santiago P, Lubrano C, Vaisse C, Conklin BR	Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo.	PLoS ONE	2:7:e668	2007	17668051		Supriya Srinivasan, Pamela Santiago, Cecile Lubrano, Christian Vaisse, Bruce R Conklin	Supriya Srinivasan	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, University of California at San Francisco, San Francisco, California, United States of America. supriya.srinivasan@ucsf.edu	NHLBI NIH HHS; HL60664-06
Nord AS, Vranizan K, Tingley W, Zambon AC, Hanspers K, Fong LG, Hu Y, Bacchetti P, Ferrin TE, Babbitt PC, Doniger SW, Skarnes WC, Young SG, Conklin BR	Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells.	PLoS ONE	2:7:e617	2007	17637833		Alex S Nord, Karen Vranizan, Whittemore Tingley, Alexander C Zambon, Kristina Hanspers, Loren G Fong, Yan Hu, Peter Bacchetti, Thomas E Ferrin, Patricia C Babbitt, Scott W Doniger, William C Skarnes, Stephen G Young, Bruce R Conklin	Alex S Nord	Bruce R Conklin	Department of Medicine, MacDonald Medical Research Laboratories, University of California at Los Angeles, California, USA. nordalex@u.washington.edu	NHLBI NIH HHS; HL66621
Salomonis N, Hanspers K, Zambon AC, Vranizan K, Lawlor SC, Dahlquist KD, Doniger SW, Stuart J, Conklin BR, Pico AR	GenMAPP 2: new features and resources for pathway analysis.	BMC Bioinformatics	8:217	2007	17588266		Nathan Salomonis, Kristina Hanspers, Alexander C Zambon, Karen Vranizan, Steven C Lawlor, Kam D Dahlquist, Scott W Doniger, Josh Stuart, Bruce R Conklin, Alexander R Pico	Nathan Salomonis	Alexander R Pico	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. nsalomonis@gladstone.ucsf.edu <nsalomonis@gladstone.ucsf.edu>	NHLBI NIH HHS; HL66621
Kim W, Ng JK, Kunitake ME, Conklin BR, Yang P	Interfacing silicon nanowires with mammalian cells.	J. Am. Chem. Soc.	129:23:7228-9	2007	17516647		Woong Kim, Jennifer K Ng, Miki E Kunitake, Bruce R Conklin, Peidong Yang	Woong Kim	Peidong Yang	The Molecular Foundry and Materials Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, California 94720, USA.	NHLBI NIH HHS; HL66621
Tingley WG, Pawlikowska L, Zaroff JG, Kim T, Nguyen T, Young SG, Vranizan K, Kwok PY, Whooley MA, Conklin BR	Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation.	Proc. Natl. Acad. Sci. U.S.A.	104:20:8461-6	2007	17485678		Whittemore G Tingley, Ludmila Pawlikowska, Jonathan G Zaroff, Taeryn Kim, Trieu Nguyen, Stephen G Young, Karen Vranizan, Pui-Yan Kwok, Mary A Whooley, Bruce R Conklin	Whittemore G Tingley	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928
Conklin BR	New tools to build synthetic hormonal pathways.	Proc. Natl. Acad. Sci. U.S.A.	104:12:4777-8	2007	17360323		Bruce R Conklin	Bruce R Conklin	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA. bconklin@gladstone.ucsf.edu	NA
Sweger EJ, Casper KB, Scearce-Levie K, Conklin BR, McCarthy KD	Development of hydrocephalus in mice expressing the G(i)-coupled GPCR Ro1 RASSL receptor in astrocytes.	J. Neurosci.	27:9:2309-17	2007	17329428		Elizabeth J Sweger, Kristen B Casper, Kimberly Scearce-Levie, Bruce R Conklin, Ken D McCarthy	Elizabeth J Sweger	Ken D McCarthy	Department of Pharmacology, University of North Carolina, Chapel Hill, North Carolina 27599, USA.	NA
Cline MS, Smoot M, Cerami E, Kuchinsky A, Landys N, Workman C, Christmas R, Avila-Campilo I, Creech M, Gross B, Hanspers K, Isserlin R, Kelley R, Killcoyne S, Lotia S, Maere S, Morris J, Ono K, Pavlovic V, Pico AR, Vailaya A, Wang PL, Adler A, Conklin BR, Hood L, Kuiper M, Sander C, Schmulevich I, Schwikowski B, Warner GJ, Ideker T, Bader GD	Integration of biological networks and gene expression data using Cytoscape.	Nat Protoc	2:10:2366-82	2007	17947979		Melissa S Cline, Michael Smoot, Ethan Cerami, Allan Kuchinsky, Nerius Landys, Chris Workman, Rowan Christmas, Iliana Avila-Campilo, Michael Creech, Benjamin Gross, Kristina Hanspers, Ruth Isserlin, Ryan Kelley, Sarah Killcoyne, Samad Lotia, Steven Maere, John Morris, Keiichiro Ono, Vuk Pavlovic, Alexander R Pico, Aditya Vailaya, Peng-Liang Wang, Annette Adler, Bruce R Conklin, Leroy Hood, Martin Kuiper, Chris Sander, Ilya Schmulevich, Benno Schwikowski, Guy J Warner, Trey Ideker, Gary D Bader	Melissa S Cline	Gary D Bader	Institut Pasteur, 25-28 rue du Docteur Roux, 75724 Paris cedex 15, France.	NIGMS NIH HHS; R01 GM070743-05
Nicholls RE, Zhang XL, Bailey CP, Conklin BR, Kandel ER, Stanton PK	mGluR2 acts through inhibitory Galpha subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses.	Proc. Natl. Acad. Sci. U.S.A.	103:16:6380-5	2006	16606834		Russell E Nicholls, Xiao-Lei Zhang, Christopher P Bailey, Bruce R Conklin, Eric R Kandel, Patric K Stanton	Russell E Nicholls	Patric K Stanton	Center for Neurobiology and Behavior, Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA.	NINDS NIH HHS; R01-NS44421
Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, Soriano P, Stanford WL, Stryke D, von Melchner H, Wurst W, Yamamura K, Young SG, Babbitt PC, Ferrin TE	The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse.	Nucleic Acids Res.	34:Database issue:D642-8	2006	16381950		Alex S Nord, Patricia J Chang, Bruce R Conklin, Antony V Cox, Courtney A Harper, Geoffrey G Hicks, Conrad C Huang, Susan J Johns, Michiko Kawamoto, Songyan Liu, Elaine C Meng, John H Morris, Janet Rossant, Patricia Ruiz, William C Skarnes, Philippe Soriano, William L Stanford, Doug Stryke, Harald von Melchner, Wolfgang Wurst, Ken-ichi Yamamura, Stephen G Young, Patricia C Babbitt, Thomas E Ferrin	Alex S Nord	Thomas E Ferrin	University of California San Francisco, 600 16th Street, San Francisco, CA 94143-2240, USA.	Wellcome Trust; 
Turnbull L, Zhou HZ, Swigart PM, Turcato S, Karliner JS, Conklin BR, Simpson PC, Baker AJ	Sustained preconditioning induced by cardiac transgenesis with the tetracycline transactivator.	Am. J. Physiol. Heart Circ. Physiol.	290:3:H1103-9	2006	16243914		Lynne Turnbull, Hui-Zhong Zhou, Philip M Swigart, Sally Turcato, Joel S Karliner, Bruce R Conklin, Paul C Simpson, Anthony J Baker	Lynne Turnbull	Anthony J Baker	Department of Radiology, University of California, San Francisco, California 94121, USA.	NHLBI NIH HHS; P01-HL-68738
Zambon AC, Zhang L, Minovitsky S, Kanter JR, Prabhakar S, Salomonis N, Vranizan K, Dubchak I, Conklin BR, Insel PA	Gene expression patterns define key transcriptional events in cell-cycle regulation by cAMP and protein kinase A.	Proc. Natl. Acad. Sci. U.S.A.	102:24:8561-6	2005	15939874		Alexander C Zambon, Lingzhi Zhang, Simon Minovitsky, Joan R Kanter, Shyam Prabhakar, Nathan Salomonis, Karen Vranizan, Inna Dubchak, Bruce R Conklin, Paul A Insel	Alexander C Zambon	Paul A Insel	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141, USA.	NHLBI NIH HHS; U1HL66681B
McCloskey DT, Turnbull L, Swigart PM, Zambon AC, Turcato S, Joho S, Grossman W, Conklin BR, Simpson PC, Baker AJ	Cardiac transgenesis with the tetracycline transactivator changes myocardial function and gene expression.	Physiol. Genomics	22:1:118-26	2005	15797971		Diana T McCloskey, Lynne Turnbull, Philip M Swigart, Alexander C Zambon, Sally Turcato, Shuji Joho, William Grossman, Bruce R Conklin, Paul C Simpson, Anthony J Baker	Diana T McCloskey	Anthony J Baker	Department of Radiology, University of California, San Francisco, USA.	NHLBI NIH HHS; P01-HL-68738
Scearce-Levie K, Lieberman MD, Elliott HH, Conklin BR	Engineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signaling.	BMC Biol.	3:3	2005	15707483		Kimberly Scearce-Levie, Michael D Lieberman, Heather H Elliott, Bruce R Conklin	Kimberly Scearce-Levie	Bruce R Conklin	The Gladstone Institute of Neurological Disease and the Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. kscearce-levie@gladstone.ucsf.edu	NA
Salomonis N, Cotte N, Zambon AC, Pollard KS, Vranizan K, Doniger SW, Dolganov G, Conklin BR	Identifying genetic networks underlying myometrial transition to labor.	Genome Biol.	6:2:R12	2005	15693941		Nathan Salomonis, Nathalie Cotte, Alexander C Zambon, Katherine S Pollard, Karen Vranizan, Scott W Doniger, Gregory Dolganov, Bruce R Conklin	Nathan Salomonis	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NIGMS NIH HHS; T32 GM07175
Srinivasan S, Lubrano-Berthelier C, Govaerts C, Picard F, Santiago P, Conklin BR, Vaisse C	Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans.	J. Clin. Invest.	114:8:1158-64	2004	15489963		Supriya Srinivasan, Cecile Lubrano-Berthelier, Cedric Govaerts, Franck Picard, Pamela Santiago, Bruce R Conklin, Christian Vaisse	Supriya Srinivasan	Christian Vaisse	Gladstone Institute of Cardiovascular Disease, UCSF, San Francisco, California 94143-0540, USA.	NHLBI NIH HHS; R01 HL-60664-06
Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J	A public gene trap resource for mouse functional genomics.	Nat. Genet.	36:6:543-4	2004	15167922		William C Skarnes, Harald von Melchner, Wolfgang Wurst, Geoff Hicks, Alex S Nord, Tony Cox, Stephen G Young, Patricia Ruiz, Phil Soriano, Marc Tessier-Lavigne, Bruce R Conklin, William L Stanford, Janet Rossant	William C Skarnes	Janet Rossant		Wellcome Trust; 077188
Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR	Time- and exercise-dependent gene regulation in human skeletal muscle.	Genome Biol.	4:10:R61	2003	14519196		Alexander C Zambon, Erin L McDearmon, Nathan Salomonis, Karen M Vranizan, Kirsten L Johansen, Deborah Adey, Joseph S Takahashi, Morris Schambelan, Bruce R Conklin	Alexander C Zambon	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, Department of Medicine, University of California, San Francisco, CA 94141, USA.	NCRR NIH HHS; RR-00083
Srinivasan S, Vaisse C, Conklin BR	Engineering the melanocortin-4 receptor to control G(s) signaling in vivo.	Ann. N. Y. Acad. Sci.	994:225-32	2003	12851320		Supriya Srinivasan, Christian Vaisse, Bruce R Conklin	Supriya Srinivasan	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141, USA. ssrinivasan@gladstone.ucsf.edu	NA
Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC, Conklin BR	MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data.	Genome Biol.	4:1:R7	2003	12540299		Scott W Doniger, Nathan Salomonis, Kam D Dahlquist, Karen Vranizan, Steven C Lawlor, Bruce R Conklin	Scott W Doniger	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.	NCRR NIH HHS; M01RR00083
Segal MR, Dahlquist KD, Conklin BR	Regression approaches for microarray data analysis.	J. Comput. Biol.	10:6:961-80	2003	14980020		Mark R Segal, Kam D Dahlquist, Bruce R Conklin	Mark R Segal	Bruce R Conklin	Department of Epidemiology and Biostatistics, University of California, San Francisco, CA 94143-0560, USA. mark@biostat.ucsf.edu	NIAID NIH HHS; AI40906
Dahlquist KD, Salomonis N, Vranizan K, Lawlor SC, Conklin BR	GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways.	Nat. Genet.	31:1:19-20	2002	11984561		Kam D Dahlquist, Nathan Salomonis, Karen Vranizan, Steven C Lawlor, Bruce R Conklin	Kam D Dahlquist	Bruce R Conklin		NA
Scearce-Levie K, Coward P, Redfern CH, Conklin BR	Tools for dissecting signaling pathways in vivo: receptors activated solely by synthetic ligands.	Meth. Enzymol.	343:232-48	2002	11665570		Kimberly Scearce-Levie, Peter Coward, Charles H Redfern, Bruce R Conklin	Kimberly Scearce-Levie	Bruce R Conklin	Gladstone Institute of Cardiovascular Disease, Departments of Medicine and Pharmacology, University of California, San Francisco, California 94141, USA.	NA
Scearce-Levie K, Coward P, Redfern CH, Conklin BR	Engineering receptors activated solely by synthetic ligands (RASSLs).	Trends Pharmacol. Sci.	22:8:414-20	2001	11479004		K Scearce-Levie, P Coward, C H Redfern, B R Conklin	K Scearce-Levie	B R Conklin	Gladstone Institute of Cardiovascular Disease, Gladstone Institute of Neurological Disease, Depts of Medicine and Pharmacology, University of California, San Francisco, PO Box 419100, San Francisco, CA 94141-9100, USA.	NA
Baker AJ, Redfern CH, Harwood MD, Simpson PC, Conklin BR	Abnormal contraction caused by expression of G(i)-coupled receptor in transgenic model of dilated cardiomyopathy.	Am. J. Physiol. Heart Circ. Physiol.	280:4:H1653-9	2001	11247776		A J Baker, C H Redfern, M D Harwood, P C Simpson, B R Conklin	A J Baker	B R Conklin	Department of Radiology, University of California, San Francisco, California 94143, USA. ajbaker@itsa.ucsf.edu	NHLBI NIH HHS; HL-60664
Chang MA, Horner JW, Conklin BR, DePinho RA, Bok D, Zack DJ	Tetracycline-inducible system for photoreceptor-specific gene expression.	Invest. Ophthalmol. Vis. Sci.	41:13:4281-7	2000	11095627		M A Chang, J W Horner, B R Conklin, R A DePinho, D Bok, D J Zack	M A Chang	D J Zack	Jules Stein Eye Institute, Department of Neurobiology, Brain Research Institute, University of California, Los Angeles, USA.	NEI NIH HHS; EY09769
Redfern CH, Degtyarev MY, Kwa AT, Salomonis N, Cotte N, Nanevicz T, Fidelman N, Desai K, Vranizan K, Lee EK, Coward P, Shah N, Warrington JA, Fishman GI, Bernstein D, Baker AJ, Conklin BR	Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.	Proc. Natl. Acad. Sci. U.S.A.	97:9:4826-31	2000	10781088		C H Redfern, M Y Degtyarev, A T Kwa, N Salomonis, N Cotte, T Nanevicz, N Fidelman, K Desai, K Vranizan, E K Lee, P Coward, N Shah, J A Warrington, G I Fishman, D Bernstein, A J Baker, B R Conklin	C H Redfern	B R Conklin	Gladstone Institute of Cardiovascular Disease and Gladstone Institute of Neurological Disease, Department of Medicine, University of California, San Francisco, CA 94141-9100, USA.	NCRR NIH HHS; MO1RR00083
Coward P, Chan SD, Wada HG, Humphries GM, Conklin BR	Chimeric G proteins allow a high-throughput signaling assay of Gi-coupled receptors.	Anal. Biochem.	270:2:242-8	1999	10334841		P Coward, S D Chan, H G Wada, G M Humphries, B R Conklin	P Coward	B R Conklin	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NA
Redfern CH, Coward P, Degtyarev MY, Lee EK, Kwa AT, Hennighausen L, Bujard H, Fishman GI, Conklin BR	Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice.	Nat. Biotechnol.	17:2:165-9	1999	10052353		C H Redfern, P Coward, M Y Degtyarev, E K Lee, A T Kwa, L Hennighausen, H Bujard, G I Fishman, B R Conklin	C H Redfern	B R Conklin	Gladstone Institute of Cardiovascular Disease, Gladstone Institute of Neurological Disease, Department of Medicine, University of California, San Francisco 94141, USA.	NHLBI NIH HHS; HL60664-01
Coward P, Wada HG, Falk MS, Chan SD, Meng F, Akil H, Conklin BR	Controlling signaling with a specifically designed Gi-coupled receptor.	Proc. Natl. Acad. Sci. U.S.A.	95:1:352-7	1998	9419379		P Coward, H G Wada, M S Falk, S D Chan, F Meng, H Akil, B R Conklin	P Coward	B R Conklin	Gladstone Institute for Cardiovascular Disease, Departments of Medicine and Pharmacology, University of California, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL02555
Kostenis E, Degtyarev MY, Conklin BR, Wess J	The N-terminal extension of Galphaq is critical for constraining the selectivity of receptor coupling.	J. Biol. Chem.	272:31:19107-10	1997	9235898		E Kostenis, M Y Degtyarev, B R Conklin, J Wess	E Kostenis	J Wess	Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA.	NA
Kostenis E, Conklin BR, Wess J	Molecular basis of receptor/G protein coupling selectivity studied by coexpression of wild type and mutant m2 muscarinic receptors with mutant G alpha(q) subunits.	Biochemistry	36:6:1487-95	1997	9063897		E Kostenis, B R Conklin, J Wess	E Kostenis	J Wess	Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, USA.	NA
Burstein ES, Bräuner-Osborne H, Spalding TA, Conklin BR, Brann MR	Interactions of muscarinic receptors with the heterotrimeric G proteins Gq and G12: transduction of proliferative signals.	J. Neurochem.	68:2:525-33	1997	9003037		E S Burstein, H Bräuner-Osborne, T A Spalding, B R Conklin, M R Brann	E S Burstein	M R Brann	Department of Psychiatry, University of Vermont, Burlington, USA.	NIGMS NIH HHS; R01 GM52737
Conklin BR, Herzmark P, Ishida S, Voyno-Yasenetskaya TA, Sun Y, Farfel Z, Bourne HR	Carboxyl-terminal mutations of Gq alpha and Gs alpha that alter the fidelity of receptor activation.	Mol. Pharmacol.	50:4:885-90	1996	8863834		B R Conklin, P Herzmark, S Ishida, T A Voyno-Yasenetskaya, Y Sun, Z Farfel, H R Bourne	B R Conklin	H R Bourne	Department of Medicine, University of California, San Francisco 94143, USA. bruce-conklin.gicd@quickmail.ucsf.edu	NHLBI NIH HHS; HL02555
Liu J, Blin N, Conklin BR, Wess J	Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis.	J. Biol. Chem.	271:11:6172-8	1996	8626406		J Liu, N Blin, B R Conklin, J Wess	J Liu	J Wess	Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892, USA.	NA
Liu J, Conklin BR, Blin N, Yun J, Wess J	Identification of a receptor/G-protein contact site critical for signaling specificity and G-protein activation.	Proc. Natl. Acad. Sci. U.S.A.	92:25:11642-6	1995	8524820		J Liu, B R Conklin, N Blin, J Yun, J Wess	J Liu	J Wess	Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Dieseases, Bethesda, MD 20892, USA.	NA
Chabre O, Conklin BR, Brandon S, Bourne HR, Limbird LE	Coupling of the alpha 2A-adrenergic receptor to multiple G-proteins. A simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system.	J. Biol. Chem.	269:8:5730-4	1994	7907086		O Chabre, B R Conklin, S Brandon, H R Bourne, L E Limbird	O Chabre	L E Limbird	Department of Pharmacology, University of California, San Francisco 94143.	NHLBI NIH HHS; K11HL02555
Voyno-Yasenetskaya T, Conklin BR, Gilbert RL, Hooley R, Bourne HR, Barber DL	G alpha 13 stimulates Na-H exchange.	J. Biol. Chem.	269:7:4721-4	1994	8106440		T Voyno-Yasenetskaya, B R Conklin, R L Gilbert, R Hooley, H R Bourne, D L Barber	T Voyno-Yasenetskaya	D L Barber	Department of Medicine, University of California, San Francisco 94143.	NIGMS NIH HHS; GM 47413
Conklin BR, Bourne HR	Homeostatic signals. Marriage of the flytrap and the serpent.	Nature	367:6458:22	1994	8107768		B R Conklin, H R Bourne	B R Conklin	H R Bourne		NA
Conklin BR, Bourne HR	Mouse coat colour reconsidered.	Nature	364:6433:110	1993	8321283		B R Conklin, H R Bourne	B R Conklin	H R Bourne		NA
Lustig KD, Conklin BR, Herzmark P, Taussig R, Bourne HR	Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq.	J. Biol. Chem.	268:19:13900-5	1993	8390980		K D Lustig, B R Conklin, P Herzmark, R Taussig, H R Bourne	K D Lustig	H R Bourne	Department of Pharmacology, University of California School of Medicine, San Francisco 94143.	NHLBI NIH HHS; K11 HL02555
Conklin BR, Bourne HR	Structural elements of G alpha subunits that interact with G beta gamma, receptors, and effectors.	Cell	73:4:631-41	1993	8388779		B R Conklin, H R Bourne	B R Conklin	H R Bourne	Department of Pharmacology, University of California School of Medicine, San Francisco 94143.	NA
Conklin BR, Farfel Z, Lustig KD, Julius D, Bourne HR	Substitution of three amino acids switches receptor specificity of Gq alpha to that of Gi alpha.	Nature	363:6426:274-6	1993	8387644		B R Conklin, Z Farfel, K D Lustig, D Julius, H R Bourne	B R Conklin	H R Bourne	Department of Pharmacology, University of California, San Francisco 94143.	NA
Chabre O, Conklin BR, Lin HY, Lodish HF, Wilson E, Ives HE, Catanzariti L, Hemmings BA, Bourne HR	A recombinant calcitonin receptor independently stimulates 3',5'-cyclic adenosine monophosphate and Ca2+/inositol phosphate signaling pathways.	Mol. Endocrinol.	6:4:551-6	1992	1316547		O Chabre, B R Conklin, H Y Lin, H F Lodish, E Wilson, H E Ives, L Catanzariti, B A Hemmings, H R Bourne	O Chabre	H R Bourne	Department of Pharmacology, University of California, San Francisco 94113.	NHLBI NIH HHS; HL-02555
Federman AD, Conklin BR, Schrader KA, Reed RR, Bourne HR	Hormonal stimulation of adenylyl cyclase through Gi-protein beta gamma subunits.	Nature	356:6365:159-61	1992	1312225		A D Federman, B R Conklin, K A Schrader, R R Reed, H R Bourne	A D Federman	H R Bourne	Department of Pharmacology, University of California San Francisco 94143.	NA
Wong YH, Conklin BR, Bourne HR	Gz-mediated hormonal inhibition of cyclic AMP accumulation.	Science	255:5042:339-42	1992	1347957		Y H Wong, B R Conklin, H R Bourne	Y H Wong	H R Bourne	Department of Pharmacology, University of California, San Francisco 94143.	NA
Conklin BR, Chabre O, Wong YH, Federman AD, Bourne HR	Recombinant Gq alpha. Mutational activation and coupling to receptors and phospholipase C.	J. Biol. Chem.	267:1:31-4	1992	1309740		B R Conklin, O Chabre, Y H Wong, A D Federman, H R Bourne	B R Conklin	H R Bourne	Department of Pharmacology, University of California, San Francisco 94143.	NHLBI NIH HHS; K11 HL02555
Bourne HR, Lustig KD, Wong YH, Conklin BR	Detection of coincident signals by G proteins and adenylyl cyclase.	Cold Spring Harb. Symp. Quant. Biol.	57:145-8	1992	1339653		H R Bourne, K D Lustig, Y H Wong, B R Conklin	H R Bourne	B R Conklin	Department of Pharmacology, Cardiovascular Research Institute, University of California School of Medicine, San Francisco 94143.	NA
Felder CC, Ma AL, Conklin BR	Carbachol-induced reverse transformation of Chinese hamster ovary cells transfected with and expressing the m5 muscarinic acetylcholine receptor.	FEBS Lett.	245:1-2:75-9	1989	2466702		C C Felder, A L Ma, B R Conklin	C C Felder	B R Conklin	National Institute of Mental Health, Section on Pharmacology, Bethesda, MD 20892.	NA
Conklin BR, Brann MR, Buckley NJ, Ma AL, Bonner TI, Axelrod J	Stimulation of arachidonic acid release and inhibition of mitogenesis by cloned genes for muscarinic receptor subtypes stably expressed in A9 L cells.	Proc. Natl. Acad. Sci. U.S.A.	85:22:8698-702	1988	2847172		B R Conklin, M R Brann, N J Buckley, A L Ma, T I Bonner, J Axelrod	B R Conklin	J Axelrod	Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, MD 20892.	NA
Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M	Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.	PLoS Pathog.	9:4:e1003302	2013	23593007		Dorothee A Vogt, Grégory Camus, Eva Herker, Brian R Webster, Chia-Lin Tsou, Warner C Greene, Tien-Sze Benedict Yen, Melanie Ott	Dorothee A Vogt	Melanie Ott	Gladstone Institute of Virology and Immunology, San Francisco, United States of America.	NIDDK NIH HHS; T32 DK060414
Webster B, Wissing S, Herker E, Ott M, Greene WC	Rapid intracellular competition between hepatitis C viral genomes as a result of mitosis.	J. Virol.	87:1:581-96	2013	23097449		Brian Webster, Silke Wissing, Eva Herker, Melanie Ott, Warner C Greene	Brian Webster	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California, USA.	NIAID NIH HHS; T32 AI060537
Roan NR, Cavrois M, Greene WC	[Role of semen-derived amyloid fibrils as facilitators of HIV infection].	Med Sci (Paris)	28:4:358-60	2012	22549858		Nadia R Roan, Marielle Cavrois, Warner C Greene	Nadia R Roan	Warner C Greene		NA
Chan JK, Greene WC	Dynamic roles for NF-κB in HTLV-I and HIV-1 retroviral pathogenesis.	Immunol. Rev.	246:1:286-310	2012	22435562		Jonathan K Chan, Warner C Greene	Jonathan K Chan	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NA
Pillai SK, Abdel-Mohsen M, Guatelli J, Skasko M, Monto A, Fujimoto K, Yukl S, Greene WC, Kovari H, Rauch A, Fellay J, Battegay M, Hirschel B, Witteck A, Bernasconi E, Ledergerber B, Günthard HF, Wong JK	Role of retroviral restriction factors in the interferon-α-mediated suppression of HIV-1 in vivo.	Proc. Natl. Acad. Sci. U.S.A.	109:8:3035-40	2012	22315404		Satish K Pillai, Mohamed Abdel-Mohsen, John Guatelli, Mark Skasko, Alexander Monto, Katsuya Fujimoto, Steven Yukl, Warner C Greene, Helen Kovari, Andri Rauch, Jacques Fellay, Manuel Battegay, Bernard Hirschel, Andrea Witteck, Enos Bernasconi, Bruno Ledergerber, Huldrych F Günthard, Joseph K Wong	Satish K Pillai	Joseph K Wong	Department of Medicine, University of California, San Francisco, CA 94143, USA. satish.pillai@ucsf.edu	NIMH NIH HHS; R21MH083573
Lassen KG, Hebbeler AM, Bhattacharyya D, Lobritz MA, Greene WC	A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs.	PLoS ONE	7:1:e30176	2012	22291913		Kara G Lassen, Andrew M Hebbeler, Darshana Bhattacharyya, Michael A Lobritz, Warner C Greene	Kara G Lassen	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America.	NA
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM	Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia.	J. Virol.	86:5:2556-70	2012	22205732		Sharof M Tugizov, Rossana Herrera, Piri Veluppillai, Deborah Greenspan, Vanessa Soros, Warner C Greene, Jay A Levy, Joel M Palefsky	Sharof M Tugizov	Joel M Palefsky	Department of Medicine, University of California San Francisco, San Francisco, California, USA. sharof.tugizov@ucsf.edu	NIDCR NIH HHS; R21 DE021011
Roan NR, Müller JA, Liu H, Chu S, Arnold F, Stürzel CM, Walther P, Dong M, Witkowska HE, Kirchhoff F, Münch J, Greene WC	Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.	Cell Host Microbe	10:6:541-50	2011	22177559		Nadia R Roan, Janis A Müller, Haichuan Liu, Simon Chu, Franziska Arnold, Christina M Stürzel, Paul Walther, Ming Dong, H Ewa Witkowska, Frank Kirchhoff, Jan Münch, Warner C Greene	Nadia R Roan	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NCI NIH HHS; P30 CA082103-01
Arnold F, Schnell J, Zirafi O, Stürzel C, Meier C, Weil T, Ständker L, Forssmann WG, Roan NR, Greene WC, Kirchhoff F, Münch J	Naturally occurring fragments from two distinct regions of the prostatic acid phosphatase form amyloidogenic enhancers of HIV infection.	J. Virol.	86:2:1244-9	2012	22090109		Franziska Arnold, Jacqueline Schnell, Onofrio Zirafi, Christina Stürzel, Christoph Meier, Tanja Weil, Ludger Ständker, Wolf-Georg Forssmann, Nadia R Roan, Warner C Greene, Frank Kirchhoff, Jan Münch	Franziska Arnold	Jan Münch	Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.	NA
Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC	Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility.	Hum. Mol. Genet.	21:1:208-18	2012	21989055		Silke Wissing, Martin Muñoz-Lopez, Angela Macia, Zhiyuan Yang, Mauricio Montano, William Collins, Jose Luis Garcia-Perez, John V Moran, Warner C Greene	Silke Wissing	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	Howard Hughes Medical Institute; 
Smith DS, Guo K, Barrett BS, Heilman KJ, Evans LH, Hasenkrug KJ, Greene WC, Santiago ML	Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.	PLoS Pathog.	7:10:e1002284	2011	21998583		Diana S Smith, Kejun Guo, Bradley S Barrett, Karl J Heilman, Leonard H Evans, Kim J Hasenkrug, Warner C Greene, Mario L Santiago	Diana S Smith	Mario L Santiago	Department of Medicine, University of Colorado Denver, Aurora, Colorado, United States of America.	NIAID NIH HHS; R56 AI084123-01
Siliciano RF, Greene WC	HIV latency.	Cold Spring Harb Perspect Med	1:1:a007096	2011	22229121		Robert F Siliciano, Warner C Greene	Robert F Siliciano	Warner C Greene	Department of Medicine, Johns Hopkins University School of Medicine, Howard Hughes Medical Institute, Baltimore, Maryland 21205, USA. rsiliciano@jhmi.edu	NA
Wissing S, Montano M, Garcia-Perez JL, Moran JV, Greene WC	Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells.	J. Biol. Chem.	286:42:36427-37	2011	21878639		Silke Wissing, Mauricio Montano, Jose Luis Garcia-Perez, John V Moran, Warner C Greene	Silke Wissing	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	Howard Hughes Medical Institute; 
Sakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M	Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).	PLoS Pathog.	7:8:e1002184	2011	21876670		Naoki Sakane, Hye-Sook Kwon, Sara Pagans, Katrin Kaehlcke, Yasuhiro Mizusawa, Masafumi Kamada, Kara G Lassen, Jonathan Chan, Warner C Greene, Martina Schnoelzer, Melanie Ott	Naoki Sakane	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, United States of America.	NA
Chan JK, Greene WC	NF-κB/Rel: agonist and antagonist roles in HIV-1 latency.	Curr Opin HIV AIDS	6:1:12-8	2011	21242888		Jonathan K L Chan, Warner C Greene	Jonathan K L Chan	Warner C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, California, USA.	NIAID NIH HHS; R21 AI080409
Doitsh G, Cavrois M, Lassen KG, Zepeda O, Yang Z, Santiago ML, Hebbeler AM, Greene WC	Abortive HIV infection mediates CD4 T cell depletion and inflammation in human lymphoid tissue.	Cell	143:5:789-801	2010	21111238		Gilad Doitsh, Marielle Cavrois, Kara G Lassen, Orlando Zepeda, Zhiyuan Yang, Mario L Santiago, Andrew M Hebbeler, Warner C Greene	Gilad Doitsh	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NIGMS NIH HHS; T32 GM007618-32
Tugizov SM, Herrera R, Veluppillai P, Greenspan D, Soros V, Greene WC, Levy JA, Palefsky JM	HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells.	Virology	409:2:211-22	2011	21056450		Sharof M Tugizov, Rossana Herrera, Piri Veluppillai, Deborah Greenspan, Vanessa Soros, Warner C Greene, Jay A Levy, Joel M Palefsky	Sharof M Tugizov	Joel M Palefsky	Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143-0512, USA. sharof.tugizov@ucsf.edu	NIDCR NIH HHS; R21 DE016009-01
Santiago ML, Smith DS, Barrett BS, Montano M, Benitez RL, Pelanda R, Hasenkrug KJ, Greene WC	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.	J. Virol.	85:1:189-99	2011	20980520		Mario L Santiago, Diana S Smith, Bradley S Barrett, Mauricio Montano, Robert L Benitez, Roberta Pelanda, Kim J Hasenkrug, Warner C Greene	Mario L Santiago	Warner C Greene	Division of Infectious Diseases, University of Colorado Denver, Mail Stop B-168, 12700 E. 19th Avenue, Aurora, CO 80045, USA. mario.santiago@ucdenver.edu	NIAID NIH HHS; R56 AI084123-01
Lassen KG, Wissing S, Lobritz MA, Santiago M, Greene WC	Identification of two APOBEC3F splice variants displaying HIV-1 antiviral activity and contrasting sensitivity to Vif.	J. Biol. Chem.	285:38:29326-35	2010	20624919		Kara G Lassen, Silke Wissing, Michael A Lobritz, Mario Santiago, Warner C Greene	Kara G Lassen	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.	NIGMS NIH HHS; T32 GM07250
Kim KA, Yolamanova M, Zirafi O, Roan NR, Staendker L, Forssmann WG, Burgener A, Dejucq-Rainsford N, Hahn BH, Shaw GM, Greene WC, Kirchhoff F, Münch J	Semen-mediated enhancement of HIV infection is donor-dependent and correlates with the levels of SEVI.	Retrovirology	7:55	2010	20573198		Kyeong-Ae Kim, Maral Yolamanova, Onofrio Zirafi, Nadia R Roan, Ludger Staendker, Wolf-Georg Forssmann, Adam Burgener, Nathalie Dejucq-Rainsford, Beatrice H Hahn, George M Shaw, Warner C Greene, Frank Kirchhoff, Jan Münch	Kyeong-Ae Kim	Jan Münch	Institute of Molecular Virology, University Hospital Ulm, 89081 Ulm, Germany.	NIAID NIH HHS; 1R01AI067057-01A2
Santiago ML, Benitez RL, Montano M, Hasenkrug KJ, Greene WC	Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.	J. Immunol.	185:2:1114-23	2010	20566830		Mario L Santiago, Robert L Benitez, Mauricio Montano, Kim J Hasenkrug, Warner C Greene	Mario L Santiago	Warner C Greene	Division of Infectious Diseases, University of Colorado Denver, Mail Stop B168, 12700 East 19th Avenue, Aurora, CO 80045, USA. mario.santiago@ucdenver.edu	NIAID NIH HHS; R56 AI084123-01
Wissing S, Galloway NL, Greene WC	HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.	Mol. Aspects Med.	31:5:383-97	2010	20538015		Silke Wissing, Nicole L K Galloway, Warner C Greene	Silke Wissing	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01 AI065329
Cavrois M, Neidleman J, Galloway N, Derdeyn CA, Hunter E, Greene WC	Measuring HIV fusion mediated by envelopes from primary viral isolates.	Methods	53:1:34-8	2011	20554044		Marielle Cavrois, Jason Neidleman, Nicole Galloway, Cynthia A Derdeyn, Eric Hunter, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA. mcavrois@gladstone.ucsf.edu	NIAID NIH HHS; R37 AI051231-11
Roan NR, Sowinski S, Münch J, Kirchhoff F, Greene WC	Aminoquinoline surfen inhibits the action of SEVI (semen-derived enhancer of viral infection).	J. Biol. Chem.	285:3:1861-9	2010	19897482		Nadia R Roan, Stefanie Sowinski, Jan Münch, Frank Kirchhoff, Warner C Greene	Nadia R Roan	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NIAID NIH HHS; P30AI027763
Chiu YL, Greene WC	APOBEC3G: an intracellular centurion.	Philos. Trans. R. Soc. Lond., B, Biol. Sci.	364:1517:689-703	2009	19008196		Ya-Lin Chiu, Warner C Greene	Ya-Lin Chiu	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928-01
Richman DD, Margolis DM, Delaney M, Greene WC, Hazuda D, Pomerantz RJ	The challenge of finding a cure for HIV infection.	Science	323:5919:1304-7	2009	19265012		Douglas D Richman, David M Margolis, Martin Delaney, Warner C Greene, Daria Hazuda, Roger J Pomerantz	Douglas D Richman	Roger J Pomerantz	San Diego VA Healthcare System and University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0679, USA. drichman@ucsd.edu	NA
Michel N, Goffinet C, Ganter K, Allespach I, Kewalramani VN, Saifuddin M, Littman DR, Greene WC, Goldsmith MA, Keppler OT	Human cyclin T1 expression ameliorates a T-cell-specific transcriptional limitation for HIV in transgenic rats, but is not sufficient for a spreading infection of prototypic R5 HIV-1 strains ex vivo.	Retrovirology	6:2	2009	19144136		Nico Michel, Christine Goffinet, Kerstin Ganter, Ina Allespach, Vineet N Kewalramani, Mohammed Saifuddin, Dan R Littman, Warner C Greene, Mark A Goldsmith, Oliver T Keppler	Nico Michel	Oliver T Keppler	Department of Virology, University of Heidelberg, 69120 Heidelberg, Germany. mail@nicomichel.de	Howard Hughes Medical Institute; 
Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D	Unsung hero Robert C. Gallo.	Science	323:5911:206-7	2009	19131607		Giovanni Abbadessa, Roberto Accolla, Fernando Aiuti, Adriana Albini, Anna Aldovini, Massimo Alfano, Guido Antonelli, Courtenay Bartholomew, Zvi Bentwich, Umberto Bertazzoni, Jay A Berzofsky, Peter Biberfeld, Enzo Boeri, Luigi Buonaguro, Franco M Buonaguro, Michael Bukrinsky, Arsène Burny, Arnaldo Caruso, Sharon Cassol, Prakash Chandra, Luca Ceccherini-Nelli, Luigi Chieco-Bianchi, Mario Clerici, Sandra Colombini-Hatch, Carlo de Giuli Morghen, Andrea de Maria, Anita de Rossi, Manfred Dierich, Riccardo Della-Favera, Antonina Dolei, Daniel Douek, Volker Erfle, Barbara Felber, Simona Fiorentini, Genoveffa Franchini, Jonathan M Gershoni, Frances Gotch, Patrick Green, Warner C Greene, William Hall, William Haseltine, Stephens Jacobson, Lars O Kallings, Vaniambadi S Kalyanaraman, Hermann Katinger, Kamel Khalili, George Klein, Eva Klein, Mary Klotman, Paul Klotman, Moshe Kotler, Reinhard Kurth, Alain Lafeuillade, Michelangelo La Placa, Jonathan Lewis, Flavia Lillo, Julianna Lisziewicz, Anita Lomonico, Lucia Lopalco, Franco Lori, Paolo Lusso, Beatrice Macchi, Michael Malim, Leonid Margolis, Phillip D Markham, Myra McClure, Nancy Miller, Maria C Mingari, Lorenzo Moretta, Douglas Noonan, Steve O'Brien, Takashi Okamoto, Ranajit Pal, Peter Palese, Amos Panet, Giuseppe Pantaleo, George Pavlakis, Mauro Pistello, Stanley Plotkin, Guido Poli, Roger Pomerantz, Antonia Radaelli, Marjorie Robertguroff, Mario Roederer, Mangalasseril G Sarngadharan, Dominique Schols, Paola Secchiero, Gene Shearer, Antonio Siccardi, Mario Stevenson, Jan Svoboda, Jim Tartaglia, Giuseppe Torelli, Maria Lina Tornesello, Erwin Tschachler, Mauro Vaccarezza, Angelika Vallbracht, Jan van Lunzen, Oliviero Varnier, Elisa Vicenzi, Harald von Melchner, Isaac Witz, Daniel Zagury, Jean-Francois Zagury, Giorgio Zauli, Donato Zipeto	Giovanni Abbadessa	Donato Zipeto		NA
LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS	Guidelines for naming nonprimate APOBEC3 genes and proteins.	J. Virol.	83:2:494-7	2009	18987154		Rebecca S LaRue, Valgerdur Andrésdóttir, Yannick Blanchard, Silvestro G Conticello, David Derse, Michael Emerman, Warner C Greene, Stefán R Jónsson, Nathaniel R Landau, Martin Löchelt, Harmit S Malik, Michael H Malim, Carsten Münk, Stephen J O'Brien, Vinay K Pathak, Klaus Strebel, Simon Wain-Hobson, Xiao-Fang Yu, Naoya Yuhki, Reuben S Harris	Rebecca S LaRue	Reuben S Harris	Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Beckman Center for Genome Engineering, Comparative and Molecular Biology Graduate Program, University of Minnesota, Minneapolis, Minnesota 55455, USA.	NA
Roan NR, Münch J, Arhel N, Mothes W, Neidleman J, Kobayashi A, Smith-McCune K, Kirchhoff F, Greene WC	The cationic properties of SEVI underlie its ability to enhance human immunodeficiency virus infection.	J. Virol.	83:1:73-80	2009	18945786		Nadia R Roan, Jan Münch, Nathalie Arhel, Walther Mothes, Jason Neidleman, Akiko Kobayashi, Karen Smith-McCune, Frank Kirchhoff, Warner C Greene	Nadia R Roan	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, P.O. Box 419100, San Francisco, CA 94141-9100, USA.	NIAID NIH HHS; 1R01AI067057-01A2
Greene WC, Debyser Z, Ikeda Y, Freed EO, Stephens E, Yonemoto W, Buckheit RW, Esté JA, Cihlar T	Novel targets for HIV therapy.	Antiviral Res.	80:3:251-65	2008	18789977		Warner C Greene, Zeger Debyser, Yasuhiro Ikeda, Eric O Freed, Edward Stephens, Wes Yonemoto, Robert W Buckheit, José A Esté, Tomas Cihlar	Warner C Greene	Tomas Cihlar	Gladstone Institute of Virology and Immunology, San Francisco, CA, USA.	NA
Santiago ML, Montano M, Benitez R, Messer RJ, Yonemoto W, Chesebro B, Hasenkrug KJ, Greene WC	Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.	Science	321:5894:1343-6	2008	18772436		Mario L Santiago, Mauricio Montano, Robert Benitez, Ronald J Messer, Wes Yonemoto, Bruce Chesebro, Kim J Hasenkrug, Warner C Greene	Mario L Santiago	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01 AI065329-04
Fauci AS, Johnston MI, Dieffenbach CW, Burton DR, Hammer SM, Hoxie JA, Martin M, Overbaugh J, Watkins DI, Mahmoud A, Greene WC	HIV vaccine research: the way forward.	Science	321:5888:530-2	2008	18653883		Anthony S Fauci, Margaret I Johnston, Carl W Dieffenbach, Dennis R Burton, Scott M Hammer, James A Hoxie, Malcolm Martin, Julie Overbaugh, David I Watkins, Adel Mahmoud, Warner C Greene	Anthony S Fauci	Warner C Greene	National Institute of Allergy and Infectious Diseases, National Institutes of Health, 31 Center Drive, Bethesda, MD 20892, USA. afauci@niaid.nih.gov	NA
Cavrois M, Neidleman J, Greene WC	The achilles heel of the trojan horse model of HIV-1 trans-infection.	PLoS Pathog.	4:6:e1000051	2008	18584030		Marielle Cavrois, Jason Neidleman, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America.	NCRR NIH HHS; RR 18928-01
Kwon HS, Brent MM, Getachew R, Jayakumar P, Chen LF, Schnolzer M, McBurney MW, Marmorstein R, Greene WC, Ott M	Human immunodeficiency virus type 1 Tat protein inhibits the SIRT1 deacetylase and induces T cell hyperactivation.	Cell Host Microbe	3:3:158-67	2008	18329615		Hye-Sook Kwon, Michael M Brent, Ruth Getachew, Prerana Jayakumar, Lin-Feng Chen, Martina Schnolzer, Michael W McBurney, Ronen Marmorstein, Warner C Greene, Melanie Ott	Hye-Sook Kwon	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; R56 AI067118-01A2
Chiu YL, Greene WC	The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.	Annu. Rev. Immunol.	26:317-53	2008	18304004		Ya-Lin Chiu, Warner C Greene	Ya-Lin Chiu	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA. ychiu@gladstone.ucsf.edu	NCRR NIH HHS; RR18928-01
Roan NR, Greene WC	A seminal finding for understanding HIV transmission.	Cell	131:6:1044-6	2007	18083095		Nadia R Roan, Warner C Greene	Nadia R Roan	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA. nroan@gladstone.ucsf.edu	NA
Greene WC	A history of AIDS: looking back to see ahead.	Eur. J. Immunol.	37 Suppl 1:S94-102	2007	17972351		Warner C Greene	Warner C Greene	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA. wgreene@gladstone.ucsf.edu	NICHD NIH HHS; HD40543
Goffinet C, Michel N, Allespach I, Tervo HM, Hermann V, Kräusslich HG, Greene WC, Keppler OT	Primary T-cells from human CD4/CCR5-transgenic rats support all early steps of HIV-1 replication including integration, but display impaired viral gene expression.	Retrovirology	4:53	2007	17655755		Christine Goffinet, Nico Michel, Ina Allespach, Hanna-Mari Tervo, Volker Hermann, Hans-Georg Kräusslich, Warner C Greene, Oliver T Keppler	Christine Goffinet	Oliver T Keppler	Department of Virology, University of Heidelberg, Heidelberg, Germany. Christine.goffinet@med.uni-heidelberg.de	NA
Williams SA, Greene WC	Regulation of HIV-1 latency by T-cell activation.	Cytokine	39:1:63-74	2007	17643313		Samuel A Williams, Warner C Greene	Samuel A Williams	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, 1650 Owens Street, San Francisco, CA 94158, USA.	NIAID NIH HHS; P01 AI058708-040002
Ellery PJ, Tippett E, Chiu YL, Paukovics G, Cameron PU, Solomon A, Lewin SR, Gorry PR, Jaworowski A, Greene WC, Sonza S, Crowe SM	The CD16+ monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo.	J. Immunol.	178:10:6581-9	2007	17475889		Philip J Ellery, Emma Tippett, Ya-Lin Chiu, Geza Paukovics, Paul U Cameron, Ajantha Solomon, Sharon R Lewin, Paul R Gorry, Anthony Jaworowski, Warner C Greene, Secondo Sonza, Suzanne M Crowe	Philip J Ellery	Suzanne M Crowe	AIDS Pathogenesis and Clinical Research Program, Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Victoria, Australia.	NA
Williams SA, Kwon H, Chen LF, Greene WC	Sustained induction of NF-kappa B is required for efficient expression of latent human immunodeficiency virus type 1.	J. Virol.	81:11:6043-56	2007	17376917		Samuel A Williams, Hakju Kwon, Lin-Feng Chen, Warner C Greene	Samuel A Williams	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR 892801
Soros VB, Greene WC	APOBEC3G and HIV-1: strike and counterstrike.	Curr HIV/AIDS Rep	4:1:3-9	2007	17338854		Vanessa B Soros, Warner C Greene	Vanessa B Soros	Warner C Greene		NA
Soros VB, Yonemoto W, Greene WC	Newly synthesized APOBEC3G is incorporated into HIV virions, inhibited by HIV RNA, and subsequently activated by RNase H.	PLoS Pathog.	3:2:e15	2007	17291161		Vanessa B Soros, Wes Yonemoto, Warner C Greene	Vanessa B Soros	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America.	NCRR NIH HHS; RR1 892801
Cavrois M, Neidleman J, Kreisberg JF, Greene WC	In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 virions.	PLoS Pathog.	3:1:e4	2007	17238285		Marielle Cavrois, Jason Neidleman, Jason F Kreisberg, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, United States of America.	NCRR NIH HHS; RR 18928-01
Stopak KS, Chiu YL, Kropp J, Grant RM, Greene WC	Distinct patterns of cytokine regulation of APOBEC3G expression and activity in primary lymphocytes, macrophages, and dendritic cells.	J. Biol. Chem.	282:6:3539-46	2007	17110377		Kim S Stopak, Ya-Lin Chiu, Jerry Kropp, Robert M Grant, Warner C Greene	Kim S Stopak	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NIAID NIH HHS; R01 AI065329
Ahuja SK, Aiuti F, Berkhout B, Biberfeld P, Burton DR, Colizzi V, Deeks SG, Desrosiers RC, Dierich MP, Doms RW, Emerman M, Gallo RC, Girard M, Greene WC, Hoxie JA, Hunter E, Klein G, Korber B, Kuritzkes DR, Lederman MM, Malim MH, Marx PA, McCune JM, McMichael A, Miller C, Miller V, Montagnier L, Montefiori DC, Moore JP, Nixon DF, Overbaugh J, Pauza CD, Richman DD, Saag MS, Sattentau Q, Schooley RT, Shattock R, Shaw GM, Stevenson M, Trkola A, Wainberg MA, Weiss RA, Wolinsky S, Zack JA	A plea for justice for jailed medical workers.	Science	314:5801:924-5	2006	17062652		Sunil K Ahuja, Fernando Aiuti, Ben Berkhout, Peter Biberfeld, Dennis R Burton, Vittorio Colizzi, Steven G Deeks, Ronald C Desrosiers, Manfred P Dierich, Robert W Doms, Michael Emerman, Robert C Gallo, Marc Girard, Warner C Greene, James A Hoxie, Eric Hunter, George Klein, Bette Korber, Daniel R Kuritzkes, Michael M Lederman, Michael H Malim, Preston A Marx, Joseph M McCune, Andrew McMichael, Christopher Miller, Veronica Miller, Luc Montagnier, David C Montefiori, John P Moore, Douglas F Nixon, Julie Overbaugh, C David Pauza, Douglas D Richman, Michael S Saag, Quentin Sattentau, Robert T Schooley, Robin Shattock, George M Shaw, Mario Stevenson, Alexandra Trkola, Mark A Wainberg, Robin A Weiss, Steven Wolinsky, Jerome A Zack	Sunil K Ahuja	Jerome A Zack		NA
Chiu YL, Witkowska HE, Hall SC, Santiago M, Soros VB, Esnault C, Heidmann T, Greene WC	High-molecular-mass APOBEC3G complexes restrict Alu retrotransposition.	Proc. Natl. Acad. Sci. U.S.A.	103:42:15588-93	2006	17030807		Ya-Lin Chiu, H Ewa Witkowska, Steven C Hall, Mario Santiago, Vanessa B Soros, Cécile Esnault, Thierry Heidmann, Warner C Greene	Ya-Lin Chiu	Warner C Greene	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928-01
O'Mahony A, Raber J, Montano M, Foehr E, Han V, Lu SM, Kwon H, LeFevour A, Chakraborty-Sett S, Greene WC	NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity.	Mol. Cell. Biol.	26:19:7283-98	2006	16980629		Alison O'Mahony, Jacob Raber, Mauricio Montano, Erik Foehr, Victor Han, Shao-ming Lu, Hakju Kwon, Anthony LeFevour, Shikha Chakraborty-Sett, Warner C Greene	Alison O'Mahony	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94141, USA.	NCRR NIH HHS; C06 RR018928
Zimmerman ES, Sherman MP, Blackett JL, Neidleman JA, Kreis C, Mundt P, Williams SA, Warmerdam M, Kahn J, Hecht FM, Grant RM, de Noronha CM, Weyrich AS, Greene WC, Planelles V	Human immunodeficiency virus type 1 Vpr induces DNA replication stress in vitro and in vivo.	J. Virol.	80:21:10407-18	2006	16956949		Erik S Zimmerman, Michael P Sherman, Jana L Blackett, Jason A Neidleman, Christophe Kreis, Pamela Mundt, Samuel A Williams, Maria Warmerdam, James Kahn, Frederick M Hecht, Robert M Grant, Carlos M C de Noronha, Andrew S Weyrich, Warner C Greene, Vicente Planelles	Erik S Zimmerman	Vicente Planelles	Division of Cellular Biology and Immunology, Department of Pathology, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA.	NA
Soros VB, Greene WC	APOBEC3G and HIV-1: strike and counterstrike.	Curr Infect Dis Rep	8:4:317-23	2006	16822376		Vanessa B Soros, Warner C Greene	Vanessa B Soros	Warner C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, 1650 Owens Street, CA 94158-2261, USA.	NA
Chiu YL, Greene WC	Multifaceted antiviral actions of APOBEC3 cytidine deaminases.	Trends Immunol.	27:6:291-7	2006	16678488		Ya-Lin Chiu, Warner C Greene	Ya-Lin Chiu	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141-9100, USA.	NIAID NIH HHS; R01 AI065329-01
Kreisberg JF, Yonemoto W, Greene WC	Endogenous factors enhance HIV infection of tissue naive CD4 T cells by stimulating high molecular mass APOBEC3G complex formation.	J. Exp. Med.	203:4:865-70	2006	16606671		Jason F Kreisberg, Wes Yonemoto, Warner C Greene	Jason F Kreisberg	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01 AI065329
Chandrasekar B, Mummidi S, Mahimainathan L, Patel DN, Bailey SR, Imam SZ, Greene WC, Valente AJ	Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inhibited by atorvastatin.	J. Biol. Chem.	281:22:15099-109	2006	16554298		Bysani Chandrasekar, Srinivas Mummidi, Lenin Mahimainathan, Devang N Patel, Steven R Bailey, Syed Z Imam, Warner C Greene, Anthony J Valente	Bysani Chandrasekar	Anthony J Valente	Department of Veterans Affairs South Texas Veterans Health Care System, San Antonio, Texas 78229-4404, USA. chandraseka@uthscsa.edu	NHLBI NIH HHS; HL68020
Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC	Human immunodeficiency virus fusion to dendritic cells declines as cells mature.	J. Virol.	80:4:1992-9	2006	16439555		Marielle Cavrois, Jason Neidleman, Jason F Kreisberg, David Fenard, Christian Callebaut, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, 1650 Owens St., San Francisco, CA 94158, USA.	NIAID NIH HHS; R03 AI062263-01A
Chiu YL, Greene WC	APOBEC3 cytidine deaminases: distinct antiviral actions along the retroviral life cycle.	J. Biol. Chem.	281:13:8309-12	2006	16407183		Ya-Lin Chiu, Warner C Greene	Ya-Lin Chiu	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141, USA.	NIAID NIH HHS; R01 AI065329
Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC	NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation.	EMBO J.	25:1:139-49	2006	16319923		Samuel A Williams, Lin-Feng Chen, Hakju Kwon, Carmen M Ruiz-Jarabo, Eric Verdin, Warner C Greene	Samuel A Williams	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Fenard D, Yonemoto W, de Noronha C, Cavrois M, Williams SA, Greene WC	Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement.	J. Immunol.	175:9:6050-7	2005	16237100		David Fenard, Wes Yonemoto, Carlos de Noronha, Marielle Cavrois, Samuel A Williams, Warner C Greene	David Fenard	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, 94158, USA.	NA
Chen LF, Williams SA, Mu Y, Nakano H, Duerr JM, Buckbinder L, Greene WC	NF-kappaB RelA phosphorylation regulates RelA acetylation.	Mol. Cell. Biol.	25:18:7966-75	2005	16135789		Lin-Feng Chen, Samuel A Williams, Yajun Mu, Hiroyasu Nakano, James M Duerr, Leonard Buckbinder, Warner C Greene	Lin-Feng Chen	Warner C Greene	Gladstone Institute of Virology and Immunology, 1650 Owens St., San Francisco, CA 94158, USA. lchen@gladstone.ucsf.edu	NCI NIH HHS; R01 CA89001-02
Kwon H, Ogle L, Benitez B, Bohuslav J, Montano M, Felsher DW, Greene WC	Lethal cutaneous disease in transgenic mice conditionally expressing type I human T cell leukemia virus Tax.	J. Biol. Chem.	280:42:35713-22	2005	16105841		Hakju Kwon, Louise Ogle, Bobby Benitez, Jan Bohuslav, Mauricio Montano, Dean W Felsher, Warner C Greene	Hakju Kwon	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.	NCI NIH HHS; R01CA89001
Chen LF, Greene WC	Assessing acetylation of NF-kappaB.	Methods	36:4:368-75	2005	16111893		Lin-Feng Chen, Warner C Greene	Lin-Feng Chen	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94158, USA.	NCI NIH HHS; R01 CA89001-02
Williams SA, Greene WC	Host factors regulating post-integration latency of HIV.	Trends Microbiol.	13:4:137-9	2005	15817380		Samuel A F Williams, Warner C Greene	Samuel A F Williams	Warner C Greene	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Stopak K, Greene WC	Protecting APOBEC3G: a potential new target for HIV drug discovery.	Curr Opin Investig Drugs	6:2:141-7	2005	15751736		Kimberly Stopak, Warner C Greene	Kimberly Stopak	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 9418, USA.	NA
Keppler OT, Allespach I, Schüller L, Fenard D, Greene WC, Fackler OT	Rodent cells support key functions of the human immunodeficiency virus type 1 pathogenicity factor Nef.	J. Virol.	79:3:1655-65	2005	15650191		Oliver T Keppler, Ina Allespach, Lismarie Schüller, David Fenard, Warner C Greene, Oliver T Fackler	Oliver T Keppler	Oliver T Fackler	Department of Virology, University of Heidelberg, Im Neuenheimer Feld 324, D-69120 Heidelberg, Germany. oliver_keppler@med.uni-heidelberg.de	NIMH NIH HHS; R01-MH64396
Yonezawa A, Cavrois M, Greene WC	Studies of ebola virus glycoprotein-mediated entry and fusion by using pseudotyped human immunodeficiency virus type 1 virions: involvement of cytoskeletal proteins and enhancement by tumor necrosis factor alpha.	J. Virol.	79:2:918-26	2005	15613320		Akihito Yonezawa, Marielle Cavrois, Warner C Greene	Akihito Yonezawa	Warner C Greene	Gladstone Institute of Virology and Immunology, 1650 Owens St., San Francisco, CA 94158, USA.	NICHD NIH HHS; P01 HD40543-03
Cavrois M, Neidleman J, Yonemoto W, Fenard D, Greene WC	HIV-1 virion fusion assay: uncoating not required and no effect of Nef on fusion.	Virology	328:1:36-44	2004	15380356		Marielle Cavrois, Jason Neidleman, Wes Yonemoto, David Fenard, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141-9100, United States.	NICHD NIH HHS; P01 HD40543
Greene WC	The brightening future of HIV therapeutics.	Nat. Immunol.	5:9:867-71	2004	15334078		Warner C Greene	Warner C Greene	Warner C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, California 94141-9100, USA. wgreene@gladstone.ucsf.edu	NA
Greene WC	Redistricting the retroviral restriction factors.	Nat. Med.	10:8:778-80	2004	15286773		Warner C Greene	Warner C Greene	Warner C Greene		NA
Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC	Prostratin antagonizes HIV latency by activating NF-kappaB.	J. Biol. Chem.	279:40:42008-17	2004	15284245		Samuel A Williams, Lin-Feng Chen, Hakju Kwon, David Fenard, Dwayne Bisgrove, Eric Verdin, Warner C Greene	Samuel A Williams	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California 94141, USA.	NA
Chen LF, Greene WC	Shaping the nuclear action of NF-kappaB.	Nat. Rev. Mol. Cell Biol.	5:5:392-401	2004	15122352		Lin-Feng Chen, Warner C Greene	Lin-Feng Chen	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA.	NA
Bohuslav J, Chen LF, Kwon H, Mu Y, Greene WC	p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.	J. Biol. Chem.	279:25:26115-25	2004	15073170		Jan Bohuslav, Lin-Feng Chen, Hakju Kwon, Yajun Mu, Warner C Greene	Jan Bohuslav	Warner C Greene	Gladstone Institute of Virology and Immunology and the Department of Medicine, University of California, San Francisco, California 94143-1234, USA.	NCI NIH HHS; R01CA089001
O'Mahony AM, Montano M, Van Beneden K, Chen LF, Greene WC	Human T-cell lymphotropic virus type 1 tax induction of biologically Active NF-kappaB requires IkappaB kinase-1-mediated phosphorylation of RelA/p65.	J. Biol. Chem.	279:18:18137-45	2004	14963024		Alison M O'Mahony, Mauricio Montano, Katrien Van Beneden, Lin-Feng Chen, Warner C Greene	Alison M O'Mahony	Warner C Greene	Gladstone Institute for Virology and Immunology, Department of Medicine, University of California, San Francisco, California 94141, USA.	NCI NIH HHS; R01CA89001
Schaeffer E, Soros VB, Greene WC	Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes.	J. Virol.	78:3:1375-83	2004	14722292		Evelyne Schaeffer, Vanessa B Soros, Warner C Greene	Evelyne Schaeffer	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA.	NCI NIH HHS; R01 CA86814
Cavrois M, Neidleman J, Bigos M, Greene WC	Fluorescence resonance energy transfer-based HIV-1 virion fusion assay.	Methods Mol. Biol.	263:333-44	2004	14976375		Marielle Cavrois, Jason Neidleman, Martin Bigos, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	NA
Greene WC, Chen LF	Regulation of NF-kappaB action by reversible acetylation.	Novartis Found. Symp.	259:208-17; discussion 218-25	2004	15171256		Warner C Greene, Lin-feng Chen	Warner C Greene	Lin-feng Chen	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94141, USA.	NIMH NIH HHS; P30 MH59037
Greene WC	How resting T cells deMURR HIV infection.	Nat. Immunol.	5:1:18-9	2004	14699403		Warner C Greene	Warner C Greene	Warner C Greene		NA
Stopak K, de Noronha C, Yonemoto W, Greene WC	HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability.	Mol. Cell	12:3:591-601	2003	14527406		Kim Stopak, Carlos de Noronha, Wes Yonemoto, Warner C Greene	Kim Stopak	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California-San Francisco, San Francisco, CA 94143, USA.	NCI NIH HHS; R01 CA 86814
Chen LF, Greene WC	Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation.	J. Mol. Med.	81:9:549-57	2003	12920522		Lin-Feng Chen, Warner C Greene	Lin-Feng Chen	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, P.O. Box 419100, San Francisco, CA 94141-9100, USA.	NIAID NIH HHS; T32 AI07305
Zander K, Sherman MP, Tessmer U, Bruns K, Wray V, Prechtel AT, Schubert E, Henklein P, Luban J, Neidleman J, Greene WC, Schubert U	Cyclophilin A interacts with HIV-1 Vpr and is required for its functional expression.	J. Biol. Chem.	278:44:43202-13	2003	12881522		Kerstin Zander, Michael P Sherman, Uwe Tessmer, Karsten Bruns, Victor Wray, Alexander T Prechtel, Evelyn Schubert, Peter Henklein, Jeremy Luban, Jason Neidleman, Warner C Greene, Ulrich Schubert	Kerstin Zander	Ulrich Schubert	Heinrich-Pette-Institute of Experimental Virology and Immunology, University of Hamburg, D-20251 Hamburg, Germany.	NIDDK NIH HHS; R01 DK59537-01
Sherman MP, de Noronha CM, Eckstein LA, Hataye J, Mundt P, Williams SA, Neidleman JA, Goldsmith MA, Greene WC	Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages.	J. Virol.	77:13:7582-9	2003	12805458		Michael P Sherman, Carlos M C de Noronha, Lauren A Eckstein, Jason Hataye, Pamela Mundt, Samuel A F Williams, Jason A Neidleman, Mark A Goldsmith, Warner C Greene	Michael P Sherman	Warner C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94141, USA.	NIAID NIH HHS; R01-AI45234
Stoddart CA, Geleziunas R, Ferrell S, Linquist-Stepps V, Moreno ME, Bare C, Xu W, Yonemoto W, Bresnahan PA, McCune JM, Greene WC	Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis.	J. Virol.	77:3:2124-33	2003	12525647		Cheryl A Stoddart, Romas Geleziunas, Sharon Ferrell, Valerie Linquist-Stepps, Mary E Moreno, Christopher Bare, Weiduan Xu, Wes Yonemoto, Patricia A Bresnahan, Joseph M McCune, Warner C Greene	Cheryl A Stoddart	Warner C Greene	Gladstone Institute of Virology and Immunology. Departments of Medicine. Microbiology and Immunology, University of California, San Francisco, California 94141, USA.	NIMH NIH HHS; P30-MH59037
Chen LF, Mu Y, Greene WC	Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.	EMBO J.	21:23:6539-48	2002	12456660		Lin-feng Chen, Yajun Mu, Warner C Greene	Lin-feng Chen	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94141, USA.	NIMH NIH HHS; P30 MH59037
Sherman MP, Schubert U, Williams SA, de Noronha CM, Kreisberg JF, Henklein P, Greene WC	HIV-1 Vpr displays natural protein-transducing properties: implications for viral pathogenesis.	Virology	302:1:95-105	2002	12429519		Michael P Sherman, Ulrich Schubert, Samuel A Williams, Carlos M C de Noronha, Jason F Kreisberg, Peter Henklein, Warner C Greene	Michael P Sherman	Warner C Greene	Gladstone Institute of Virology and Immunology, San Fransisco, California 94141, USA.	NIDDK NIH HHS; R01 DK59537-01
Cavrois M, De Noronha C, Greene WC	A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes.	Nat. Biotechnol.	20:11:1151-4	2002	12355096		Marielle Cavrois, Carlos De Noronha, Warner C Greene	Marielle Cavrois	Warner C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141-9100, USA.	NICHD NIH HHS; P01 HD40543
Sherman MP, De Noronha CM, Williams SA, Greene WC	Insights into the biology of HIV-1 viral protein R.	DNA Cell Biol.	21:9:679-88	2002	12396611		Michael P Sherman, Carlos M C De Noronha, Samuel A Williams, Warner C Greene	Michael P Sherman	Warner C Greene	Gladstone Institute of Virology and Immunology and Department of Medicine, University of California, San Francisco, California 94141-9100, USA.	NA
Greene WC, Peterlin BM	Charting HIV's remarkable voyage through the cell: Basic science as a passport to future therapy.	Nat. Med.	8:7:673-80	2002	12091904		Warner C Greene, B Matija Peterlin	Warner C Greene	B Matija Peterlin	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California at San Francisco, San Francisco, California, USA. wgreene@gladstone.ucsf.edu	NIAID NIH HHS; R01AI49104
Sherman MP, Greene WC	Slipping through the door: HIV entry into the nucleus.	Microbes Infect.	4:1:67-73	2002	11825777		Michael P Sherman, Warner C Greene	Michael P Sherman	Warner C Greene	Gladstone Institute of Virology and Immunology, P.O. Box 419100, San Francisco, CA 94141-9100, USA. msherman@gladstone.ucsf.edu	NIAID NIH HHS; R01 AI45324
Eckstein DA, Sherman MP, Penn ML, Chin PS, De Noronha CM, Greene WC, Goldsmith MA	HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells.	J. Exp. Med.	194:10:1407-19	2001	11714748		D A Eckstein, M P Sherman, M L Penn, P S Chin, C M De Noronha, W C Greene, M A Goldsmith	D A Eckstein	M A Goldsmith	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, CA 94141, USA.	NIAID NIH HHS; R01-AI 43695
de Noronha CM, Sherman MP, Lin HW, Cavrois MV, Moir RD, Goldman RD, Greene WC	Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.	Science	294:5544:1105-8	2001	11691994		C M de Noronha, M P Sherman, H W Lin, M V Cavrois, R D Moir, R D Goldman, W C Greene	C M de Noronha	W C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, CA 94103, USA.	NIAID NIH HHS; R01 AI145234
Chen Lf W, Fischle E, Verdin WC	Duration of nuclear NF-kappaB action regulated by reversible acetylation.	Science	293:5535:1653-7	2001	11533489		W Chen Lf, E Fischle, W C Verdin	W Chen Lf	 Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, CA 94141, USA.	NIMH NIH HHS; P30MH59037
Geleziunas R, Xu W, Takeda K, Ichijo H, Greene WC	HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell.	Nature	410:6830:834-8	2001	11298454		R Geleziunas, W Xu, K Takeda, H Ichijo, W C Greene	R Geleziunas	W C Greene	Gladstone Institute of Virology and Immunology, PO Box 419100, San Francisco, California 94141-9100, USA.	NA
Schaeffer E, Geleziunas R, Greene WC	Human immunodeficiency virus type 1 Nef functions at the level of virus entry by enhancing cytoplasmic delivery of virions.	J. Virol.	75:6:2993-3000	2001	11222724		E Schaeffer, R Geleziunas, W C Greene	E Schaeffer	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA.	NIAID NIH HHS; R01 AI28240
Sherman MP, de Noronha CM, Heusch MI, Greene S, Greene WC	Nucleocytoplasmic shuttling by human immunodeficiency virus type 1 Vpr.	J. Virol.	75:3:1522-32	2001	11152524		M P Sherman, C M de Noronha, M I Heusch, S Greene, W C Greene	M P Sherman	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141-9100, USA.	NIMH NIH HHS; P30 MH59037
Foehr ED, Bohuslav J, Chen LF, DeNoronha C, Geleziunas R, Lin X, O'Mahony A, Greene WC	The NF-kappa B-inducing kinase induces PC12 cell differentiation and prevents apoptosis.	J. Biol. Chem.	275:44:34021-4	2000	10980190		E D Foehr, J Bohuslav, L F Chen, C DeNoronha, R Geleziunas, X Lin, A O'Mahony, W C Greene	E D Foehr	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA. efoehr@gladstone.ucsf.edu	NIMH NIH HHS; P30MH59037
Foehr ED, Lin X, O'Mahony A, Geleziunas R, Bradshaw RA, Greene WC	NF-kappa B signaling promotes both cell survival and neurite process formation in nerve growth factor-stimulated PC12 cells.	J. Neurosci.	20:20:7556-63	2000	11027214		E D Foehr, X Lin, A O'Mahony, R Geleziunas, R A Bradshaw, W C Greene	E D Foehr	W C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, San Francisco, California 94141-9100, USA.	NIMH NIH HHS; P30-MH 59037
Henklein P, Bruns K, Sherman MP, Tessmer U, Licha K, Kopp J, de Noronha CM, Greene WC, Wray V, Schubert U	Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.	J. Biol. Chem.	275:41:32016-26	2000	10903315		P Henklein, K Bruns, M P Sherman, U Tessmer, K Licha, J Kopp, C M de Noronha, W C Greene, V Wray, U Schubert	P Henklein	U Schubert	Humboldt University, Institute of Biochemistry, 10115 Berlin, Germany.	NIAID NIH HHS; R01 AI45324
Lin L, DeMartino GN, Greene WC	Cotranslational dimerization of the Rel homology domain of NF-kappaB1 generates p50-p105 heterodimers and is required for effective p50 production.	EMBO J.	19:17:4712-22	2000	10970863		L Lin, G N DeMartino, W C Greene	L Lin	W C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, Microbiology and Immunology, University of California, San Francisco, CA 94141, USA. llin1@mail.jhmi.edu	NIDDK NIH HHS; R01DK46181
Sherman MP, de Noronha CM, Pearce D, Greene WC	Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest.	J. Virol.	74:17:8159-65	2000	10933727		M P Sherman, C M de Noronha, D Pearce, W C Greene	M P Sherman	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, USA.	NIMH NIH HHS; P30MH59037
Lin X, O'Mahony A, Mu Y, Geleziunas R, Greene WC	Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta.	Mol. Cell. Biol.	20:8:2933-40	2000	10733597		X Lin, A O'Mahony, Y Mu, R Geleziunas, W C Greene	X Lin	W C Greene	Gladstone Institute of Virology and Immunology, Departments of Medicine and Microbiology and Immunology, University of California, San Francisco, California 94141, USA.	NIMH NIH HHS; MH 59037
O'Mahony A, Lin X, Geleziunas R, Greene WC	Activation of the heterodimeric IkappaB kinase alpha (IKKalpha)-IKKbeta complex is directional: IKKalpha regulates IKKbeta under both basal and stimulated conditions.	Mol. Cell. Biol.	20:4:1170-8	2000	10648602		A O'Mahony, X Lin, R Geleziunas, W C Greene	A O'Mahony	W C Greene	Gladstone Institute of Virology and Immunology, Microbiology and Immunology, University of California, San Francisco, California 94141, USA.	PHS HHS; P30A127763
Heusch M, Lin L, Geleziunas R, Greene WC	The generation of nfkb2 p52: mechanism and efficiency.	Oncogene	18:46:6201-8	1999	10597218		M Heusch, L Lin, R Geleziunas, W C Greene	M Heusch	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141-9100, USA.	NA
Bresnahan PA, Yonemoto W, Greene WC	Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4.	J. Immunol.	163:6:2977-81	1999	10477559		P A Bresnahan, W Yonemoto, W C Greene	P A Bresnahan	W C Greene	Gladstone Institute of Virology, Department of Medicine, University of California, San Francisco 94141, USA.	NIAID NIH HHS; R01-AI28240-10
Lin X, Cunningham ET, Mu Y, Geleziunas R, Greene WC	The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases.	Immunity	10:2:271-80	1999	10072079		X Lin, E T Cunningham, Y Mu, R Geleziunas, W C Greene	X Lin	W C Greene	Gladstone Institute of Virology and Immunology, University of California San Francisco, 94141, USA.	PHS HHS; P30A127763
Jenkins Y, McEntee M, Weis K, Greene WC	Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways.	J. Cell Biol.	143:4:875-85	1998	9817747		Y Jenkins, M McEntee, K Weis, W C Greene	Y Jenkins	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141-9100, USA.	PHS HHS; P30A127763
Bresnahan PA, Yonemoto W, Ferrell S, Williams-Herman D, Geleziunas R, Greene WC	A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor.	Curr. Biol.	8:22:1235-8	1998	9811606		P A Bresnahan, W Yonemoto, S Ferrell, D Williams-Herman, R Geleziunas, W C Greene	P A Bresnahan	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141, USA.	NIAID NIH HHS; R01-AI28240-10
Lin X, Mu Y, Cunningham ET, Marcu KB, Geleziunas R, Greene WC	Molecular determinants of NF-kappaB-inducing kinase action.	Mol. Cell. Biol.	18:10:5899-907	1998	9742107		X Lin, Y Mu, E T Cunningham, K B Marcu, R Geleziunas, W C Greene	X Lin	W C Greene	Gladstone Institute of Virology and Immunology, Microbiology and Immunology, University of California, San Francisco, California 94141, USA.	NEI NIH HHS; K08-EY00352
Liegler TJ, Yonemoto W, Elbeik T, Vittinghoff E, Buchbinder SP, Greene WC	Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors.	J. Infect. Dis.	178:3:669-79	1998	9728534		T J Liegler, W Yonemoto, T Elbeik, E Vittinghoff, S P Buchbinder, W C Greene	T J Liegler	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94141-9100, USA. Teri_Liegler@quickmail.ucsf.edu	NCRR NIH HHS; RR-00083
Geleziunas R, Ferrell S, Lin X, Mu Y, Cunningham ET, Grant M, Connelly MA, Hambor JE, Marcu KB, Greene WC	Human T-cell leukemia virus type 1 Tax induction of NF-kappaB involves activation of the IkappaB kinase alpha (IKKalpha) and IKKbeta cellular kinases.	Mol. Cell. Biol.	18:9:5157-65	1998	9710600		R Geleziunas, S Ferrell, X Lin, Y Mu, E T Cunningham, M Grant, M A Connelly, J E Hambor, K B Marcu, W C Greene	R Geleziunas	W C Greene	Gladstone Institute of Virology and Immunology, Microbiology, and Immunology University of California, San Francisco, San Francisco, California 94141-9100, USA. Romas_Geleziunas@quickmail.ucsf.edu	PHS HHS; P30A127763
Lin L, DeMartino GN, Greene WC	Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome.	Cell	92:6:819-28	1998	9529257		L Lin, G N DeMartino, W C Greene	L Lin	W C Greene	Gladstone Institute of Virology and Immunology, Department of Microbiology and Immunology, University of California, San Francisco 94141, USA.	NIDDK NIH HHS; R01 DK46181
Liu KD, Gaffen SL, Goldsmith MA, Greene WC	Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation.	Curr. Biol.	7:11:817-26	1997	9382798		K D Liu, S L Gaffen, M A Goldsmith, W C Greene	K D Liu	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94141-9100, USA.	NIGMS NIH HHS; GM-54351
Ghoda L, Lin X, Greene WC	The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro.	J. Biol. Chem.	272:34:21281-8	1997	9261139		L Ghoda, X Lin, W C Greene	L Ghoda	W C Greene	University of Colorado Health Sciences Center, Department of Pharmacology, School of Medicine, Denver, Colorado 80262, USA.	NIAID NIH HHS; P30 AI27763-08
Miller MD, Warmerdam MT, Ferrell SS, Benitez R, Greene WC	Intravirion generation of the C-terminal core domain of HIV-1 Nef by the HIV-1 protease is insufficient to enhance viral infectivity.	Virology	234:2:215-25	1997	9268152		M D Miller, M T Warmerdam, S S Ferrell, R Benitez, W C Greene	M D Miller	W C Greene	The Gladstone Institute of Virology and Immunology, San Francisco, California 94141, USA.	NIAID NIH HHS; AI-28240
Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC	HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing.	Proc. Natl. Acad. Sci. U.S.A.	94:3:973-8	1997	9023367		D M Powell, M C Amaral, J Y Wu, T Maniatis, W C Greene	D M Powell	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141-9100, USA.	NIAID NIH HHS; 5T32 AI077334-07
Tie F, Adya N, Greene WC, Giam CZ	Interaction of the human T-lymphotropic virus type 1 Tax dimer with CREB and the viral 21-base-pair repeat.	J. Virol.	70:12:8368-74	1996	8970957		F Tie, N Adya, W C Greene, C Z Giam	F Tie	C Z Giam	Department of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, USA.	NCI NIH HHS; R01 CA48709
Geleziunas R, Miller MD, Greene WC	Unraveling the function of HIV type 1 Nef.	AIDS Res. Hum. Retroviruses	12:17:1579-82	1996	8947291		R Geleziunas, M D Miller, W C Greene	R Geleziunas	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141, USA.	NA
Shapiro VS, Mollenauer MN, Greene WC, Weiss A	c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.	J. Exp. Med.	184:5:1663-9	1996	8920856		V S Shapiro, M N Mollenauer, W C Greene, A Weiss	V S Shapiro	A Weiss	Department of Medicine, University of California San Francisco, California 94143, USA.	NA
Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MA	Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.	J. Biol. Chem.	271:35:21381-90	1996	8702919		S L Gaffen, S Y Lai, M Ha, X Liu, L Hennighausen, W C Greene, M A Goldsmith	S L Gaffen	M A Goldsmith	Gladstone Institute of Virology and Immunology, San Francisco, California 94141, USA.	NIGMS NIH HHS; R01 GM54351
Kim JH, McLinden RJ, Mosca JD, Vahey MT, Greene WC, Redfield RR	Inhibition of HIV replication by sense and antisense rev response elements in HIV-based retroviral vectors.	J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.	12:4:343-51	1996	8673542		J H Kim, R J McLinden, J D Mosca, M T Vahey, W C Greene, R R Redfield	J H Kim	R R Redfield	University of Maryland, Medical Biotechnology Center, Baltimore 21201, USA.	NIAID NIH HHS; K11 AI00950-02
Liu KD, Greene WC, Goldsmith MA	The alpha chain of the IL-2 receptor determines the species specificity of high-affinity IL-2 binding.	Cytokine	8:8:613-21	1996	8894436		K D Liu, W C Greene, M A Goldsmith	K D Liu	M A Goldsmith	Gladstone Institute of Virology and Immunology, School of Medicine, University of California, San Francisco 94141, USA.	NA
Greene WC	Denying HIV safe haven.	N. Engl. J. Med.	334:19:1264-5	1996	8606724		W C Greene	W C Greene	W C Greene		NA
Hsu DK, Hammes SR, Kuwabara I, Greene WC, Liu FT	Human T lymphotropic virus-I infection of human T lymphocytes induces expression of the beta-galactoside-binding lectin, galectin-3.	Am. J. Pathol.	148:5:1661-70	1996	8623933		D K Hsu, S R Hammes, I Kuwabara, W C Greene, F T Liu	D K Hsu	F T Liu	Scripps Research Institute, La Jolla, California 92037, USA.	NCRR NIH HHS; M01RR00833
Miller MD, Greene WC	Is the Nef protein of HIV-1 required for pathogenesis?	Trends Microbiol.	4:5:171-2; discussion 173	1996	8727595		M D Miller, W C Greene	M D Miller	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94141, USA. Michael_Miller@quickmail.ucsf.edu	NA
Sun S, Elwood J, Greene WC	Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation.	Mol. Cell. Biol.	16:3:1058-65	1996	8622650		S Sun, J Elwood, W C Greene	S Sun	W C Greene	Gladstone Institute of Virology and Immunology, University California, San Francisco 94141-9100 USA.	NA
Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MA	The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes.	Proc. Natl. Acad. Sci. U.S.A.	93:1:231-5	1996	8552611		S Y Lai, W Xu, S L Gaffen, K D Liu, G D Longmore, W C Greene, M A Goldsmith	S Y Lai	M A Goldsmith	Gladstone Institute of Virology and Immunology, San Francisco, CA 94141, USA.	NA
Béraud C, Greene WC	Interaction of HTLV-I Tax with the human proteasome: implications for NF-kappa B induction.	J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.	13 Suppl 1:S76-84	1996	8797708		C Béraud, W C Greene	C Béraud	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California, USA.	NA
Evans GA, Goldsmith MA, Johnston JA, Xu W, Weiler SR, Erwin R, Howard OM, Abraham RT, O'Shea JJ, Greene WC	Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association.	J. Biol. Chem.	270:48:28858-63	1995	7499411		G A Evans, M A Goldsmith, J A Johnston, W Xu, S R Weiler, R Erwin, O M Howard, R T Abraham, J J O'Shea, W C Greene	G A Evans	W C Greene	Biological Carcinogenesis and Development Program, Scientific Applications International Corporation, Frederick, Maryland 21702-1201, USA.	NA
Greene WC	Predicting progression to AIDS.	Ann. Intern. Med.	123:9:726-7	1995	7574230		W C Greene	W C Greene	W C Greene		NA
Liu KD, Lai SY, Goldsmith MA, Greene WC	Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction.	J. Biol. Chem.	270:38:22176-81	1995	7545674		K D Liu, S Y Lai, M A Goldsmith, W C Greene	K D Liu	W C Greene	Gladstone Institute of Virology and Immunology, School of Medicine, University of California, San Francisco 94141, USA.	NA
Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WC	Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.	J. Biol. Chem.	270:37:21729-37	1995	7665592		M A Goldsmith, S Y Lai, W Xu, M C Amaral, E S Kuczek, L J Parent, G B Mills, K L Tarr, G D Longmore, W C Greene	M A Goldsmith	W C Greene	Gladstone Institute of Virology and Immunology, Department of Medicine, School of Medicine, University of California, San Francisco 94141-9100, USA.	NA
Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WC	Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity.	Proc. Natl. Acad. Sci. U.S.A.	92:16:7192-6	1995	7543676		S L Gaffen, S Y Lai, W Xu, F Gouilleux, B Groner, M A Goldsmith, W C Greene	S L Gaffen	W C Greene	Gladstone Institute of Virology and Immunology, School of Medicine, University of California, San Francisco 94143, USA.	NA
Goldsmith MA, Warmerdam MT, Atchison RE, Miller MD, Greene WC	Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef.	J. Virol.	69:7:4112-21	1995	7769669		M A Goldsmith, M T Warmerdam, R E Atchison, M D Miller, W C Greene	M A Goldsmith	W C Greene	Gladstone Institute of Virology and Immunology, School of Medicine, University of California San Francisco 94141, USA.	NIAID NIH HHS; AI28240-06
Goldsmith MA, Amaral MC, Greene WC	Ligand binding by the IL-2 receptor is modulated by intracellular determinants of the IL-2 receptor beta-chain.	J. Immunol.	154:5:2033-40	1995	7868880		M A Goldsmith, M C Amaral, W C Greene	M A Goldsmith	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco General Hospital, CA.	NA
Miller MD, Warmerdam MT, Page KA, Feinberg MB, Greene WC	Expression of the human immunodeficiency virus type 1 (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp160 or viral entry.	J. Virol.	69:1:579-84	1995	7983759		M D Miller, M T Warmerdam, K A Page, M B Feinberg, W C Greene	M D Miller	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, California 94141.	NA
Sun SC, Elwood J, Béraud C, Greene WC	Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.	Mol. Cell. Biol.	14:11:7377-84	1994	7935451		S C Sun, J Elwood, C Béraud, W C Greene	S C Sun	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141-9100, USA.	NA
Miller MD, Feinberg MB, Greene WC	The HIV-1 nef gene acts as a positive viral infectivity factor.	Trends Microbiol.	2:8:294-8	1994	7981973		M D Miller, M B Feinberg, W C Greene	M D Miller	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco, CA 94141.	NA
Goldsmith MA, Xu W, Amaral MC, Kuczek ES, Greene WC	The cytoplasmic domain of the interleukin-2 receptor beta chain contains both unique and functionally redundant signal transduction elements.	J. Biol. Chem.	269:20:14698-704	1994	8182077		M A Goldsmith, W Xu, M C Amaral, E S Kuczek, W C Greene	M A Goldsmith	W C Greene	Gladstone Institute of Virology and Immunology, San Francisco Hospital, California 94141-9100.	NIAID NIH HHS; AI 07395-04
Williamson P, Merida I, Greene WC, Gaulton G	The membrane proximal segment of the IL-2 receptor beta-chain acidic region is essential for IL2-dependent protein tyrosine kinase activation.	Leukemia	8 Suppl 1:S186-9	1994	8152289		P Williamson, I Merida, W C Greene, G Gaulton	P Williamson	G Gaulton	Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia 19104.	NA
Sun SC, Ganchi PA, Béraud C, Ballard DW, Greene WC	Autoregulation of the NF-kappa B transactivator RelA (p65) by multiple cytoplasmic inhibitors containing ankyrin motifs.	Proc. Natl. Acad. Sci. U.S.A.	91:4:1346-50	1994	8108414		S C Sun, P A Ganchi, C Béraud, D W Ballard, W C Greene	S C Sun	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco General Hospital 94141-9100.	NCI NIH HHS; 5T32CA09111
Béraud C, Sun SC, Ganchi P, Ballard DW, Greene WC	Human T-cell leukemia virus type I Tax associates with and is negatively regulated by the NF-kappa B2 p100 gene product: implications for viral latency.	Mol. Cell. Biol.	14:2:1374-82	1994	8289813		C Béraud, S C Sun, P Ganchi, D W Ballard, W C Greene	C Béraud	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141-9100.	NA
Miller MD, Warmerdam MT, Gaston I, Greene WC, Feinberg MB	The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages.	J. Exp. Med.	179:1:101-13	1994	8270859		M D Miller, M T Warmerdam, I Gaston, W C Greene, M B Feinberg	M D Miller	M B Feinberg	Gladstone Institute of Virology and Immunology, San Francisco, California 94141-9100.	NIAID NIH HHS; AI-28240
Ganchi PA, Sun SC, Greene WC, Ballard DW	A novel NF-kappa B complex containing p65 homodimers: implications for transcriptional control at the level of subunit dimerization.	Mol. Cell. Biol.	13:12:7826-35	1993	8246997		P A Ganchi, S C Sun, W C Greene, D W Ballard	P A Ganchi	D W Ballard	Gladstone Institute of Virology and Immunology, University of California, San Francisco General Hospital 94141-9100.	NA
Stein B, Baldwin AS, Ballard DW, Greene WC, Angel P, Herrlich P	Cross-coupling of the NF-kappa B p65 and Fos/Jun transcription factors produces potentiated biological function.	EMBO J.	12:10:3879-91	1993	8404856		B Stein, A S Baldwin, D W Ballard, W C Greene, P Angel, P Herrlich	B Stein	P Herrlich	Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill 27599.	NCI NIH HHS; CA 52515
Greene WC	AIDS and the immune system.	Sci. Am.	269:3:98-105	1993	8211096		W C Greene	W C Greene	W C Greene	Gladstone Institute of Virology and Immunology.	NA
Bogerd H, Greene WC	Dominant negative mutants of human T-cell leukemia virus type I Rex and human immunodeficiency virus type 1 Rev fail to multimerize in vivo.	J. Virol.	67:5:2496-502	1993	8474155		H Bogerd, W C Greene	H Bogerd	W C Greene	Department of Medicine, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Kuziel WA, Ju G, Grdina TA, Greene WC	Unexpected effects of the IL-2 receptor alpha subunit on high affinity IL-2 receptor assembly and function detected with a mutant IL-2 analog.	J. Immunol.	150:8 Pt 1:3357-65	1993	8468475		W A Kuziel, G Ju, T A Grdina, W C Greene	W A Kuziel	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Durham, NC.	NA
Sun SC, Ganchi PA, Ballard DW, Greene WC	NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway.	Science	259:5103:1912-5	1993	8096091		S C Sun, P A Ganchi, D W Ballard, W C Greene	S C Sun	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco.	NCI NIH HHS; 5T32CA09111
Merida I, Williamson P, Kuziel WA, Greene WC, Gaulton GN	The serine-rich cytoplasmic domain of the interleukin-2 receptor beta chain is essential for interleukin-2-dependent tyrosine protein kinase and phosphatidylinositol-3-kinase activation.	J. Biol. Chem.	268:9:6765-70	1993	8384218		I Merida, P Williamson, W A Kuziel, W C Greene, G N Gaulton	I Merida	G N Gaulton	Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104.	NIGMS NIH HHS; R01 GM42626
Hammes SR, Greene WC	Multiple arginine residues within the basic domain of HTLV-I Rex are required for specific RNA binding and function.	Virology	193:1:41-9	1993	8438577		S R Hammes, W C Greene	S R Hammes	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NIGMS NIH HHS; 5T32GM07171
Doerre S, Sista P, Sun SC, Ballard DW, Greene WC	The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virus.	Proc. Natl. Acad. Sci. U.S.A.	90:3:1023-7	1993	8430069		S Doerre, P Sista, S C Sun, D W Ballard, W C Greene	S Doerre	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.	NA
Ganchi PA, Sun SC, Greene WC, Ballard DW	I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.	Mol. Biol. Cell	3:12:1339-52	1992	1493333		P A Ganchi, S C Sun, W C Greene, D W Ballard	P A Ganchi	D W Ballard	Gladstone Institute of Virology and Immunology, University of California, San Francisco.	NCI NIH HHS; 5T32CA-09111
Mills GB, Arima N, May C, Hill M, Schmandt R, Li J, Miyamoto NG, Greene WC	Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells.	Int. Immunol.	4:11:1233-43	1992	1472476		G B Mills, N Arima, C May, M Hill, R Schmandt, J Li, N G Miyamoto, W C Greene	G B Mills	W C Greene	Toronto General Hospital, Ontario, Canada.	NA
Walker WH, Stein B, Ganchi PA, Hoffman JA, Kaufman PA, Ballard DW, Hannink M, Greene WC	The v-rel oncogene: insights into the mechanism of transcriptional activation, repression, and transformation.	J. Virol.	66:8:5018-29	1992	1321284		W H Walker, B Stein, P A Ganchi, J A Hoffman, P A Kaufman, D W Ballard, M Hannink, W C Greene	W H Walker	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Feinberg MB, Greene WC	Molecular insights into human immunodeficiency virus type 1 pathogenesis.	Curr. Opin. Immunol.	4:4:466-74	1992	1356348		M B Feinberg, W C Greene	M B Feinberg	W C Greene	Gladstone Institute of Virology and Immunology, University of California, San Francisco.	NA
Weichselbraun I, Berger J, Dobrovnik M, Bogerd H, Grassmann R, Greene WC, Hauber J, Böhnlein E	Dominant-negative mutants are clustered in a domain of the human T-cell leukemia virus type I Rex protein: implications for trans dominance.	J. Virol.	66:7:4540-5	1992	1602559		I Weichselbraun, J Berger, M Dobrovnik, H Bogerd, R Grassmann, W C Greene, J Hauber, E Böhnlein	I Weichselbraun	E Böhnlein	SANDOZ Research Institute, Vienna, Austria.	NA
Kaufman PA, Weinberg JB, Greene WC	Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-kappa B is differentially regulated in human monocytic cells.	J. Clin. Invest.	90:1:121-9	1992	1634604		P A Kaufman, J B Weinberg, W C Greene	P A Kaufman	W C Greene	Howard Hughes Medical Institute, Durham, North Carolina.	NCI NIH HHS; 5 KII CA01458-02
Arima N, Kuziel WA, Grdina TA, Greene WC	IL-2-induced signal transduction involves the activation of nuclear NF-kappa B expression.	J. Immunol.	149:1:83-91	1992	1607664		N Arima, W A Kuziel, T A Grdina, W C Greene	N Arima	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NA
Smith MR, Greene WC	Characterization of a novel nuclear localization signal in the HTLV-I tax transactivator protein.	Virology	187:1:316-20	1992	1736534		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Ballard DW, Dixon EP, Peffer NJ, Bogerd H, Doerre S, Stein B, Greene WC	The 65-kDa subunit of human NF-kappa B functions as a potent transcriptional activator and a target for v-Rel-mediated repression.	Proc. Natl. Acad. Sci. U.S.A.	89:5:1875-9	1992	1542686		D W Ballard, E P Dixon, N J Peffer, H Bogerd, S Doerre, B Stein, W C Greene	D W Ballard	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NA
Arima N, Molitor JA, Smith MR, Kim JH, Daitoku Y, Greene WC	Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation.	J. Virol.	65:12:6892-9	1991	1719236		N Arima, J A Molitor, M R Smith, J H Kim, Y Daitoku, W C Greene	N Arima	W C Greene	Department of Medicine, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NIGMS NIH HHS; T32-GM07184
Molitor JA, Ballard DW, Greene WC	Kappa B-specific DNA binding proteins are differentially inhibited by enhancer mutations and biological oxidation.	New Biol.	3:10:987-96	1991	1768652		J A Molitor, D W Ballard, W C Greene	J A Molitor	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NIGMS NIH HHS; T32-GM07337
Smith MR, Greene WC	Type I human T cell leukemia virus tax protein transforms rat fibroblasts through the cyclic adenosine monophosphate response element binding protein/activating transcription factor pathway.	J. Clin. Invest.	88:3:1038-42	1991	1832173		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Durham, North Carolina.	NA
Bogerd HP, Huckaby GL, Ahmed YF, Hanly SM, Greene WC	The type I human T-cell leukemia virus (HTLV-I) Rex trans-activator binds directly to the HTLV-I Rex and the type 1 human immunodeficiency virus Rev RNA response elements.	Proc. Natl. Acad. Sci. U.S.A.	88:13:5704-8	1991	1905815		H P Bogerd, G L Huckaby, Y F Ahmed, S M Hanly, W C Greene	H P Bogerd	W C Greene	Department of Medicine, Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.	NA
Lee JH, Li YC, Doerre S, Sista P, Ballard DW, Greene WC, Franza BR	A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene.	Oncogene	6:4:665-7	1991	2030915		J H Lee, Y C Li, S Doerre, P Sista, D W Ballard, W C Greene, B R Franza	J H Lee	B R Franza	Cold Spring Harbor Laboratory, New York 11724.	NA
Hémar A, Cereghini S, Cornet V, Blank V, Israël A, Greene WC, Dautry-Varsat A	Kappa B binding proteins are constitutively expressed in an IL-2 autocrine human T cell line.	J. Immunol.	146:7:2409-16	1991	2005404		A Hémar, S Cereghini, V Cornet, V Blank, A Israël, W C Greene, A Dautry-Varsat	A Hémar	A Dautry-Varsat	Unité de Génétique Somatique, Institut Pasteur, Paris, France.	NA
Smith MR, Greene WC	Molecular biology of the type I human T-cell leukemia virus (HTLV-I) and adult T-cell leukemia.	J. Clin. Invest.	87:3:761-6	1991	1999493		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Ahmed YF, Gilmartin GM, Hanly SM, Nevins JR, Greene WC	The HTLV-I Rex response element mediates a novel form of mRNA polyadenylation.	Cell	64:4:727-37	1991	1671761		Y F Ahmed, G M Gilmartin, S M Hanly, J R Nevins, W C Greene	Y F Ahmed	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Greene WC	The molecular biology of human immunodeficiency virus type 1 infection.	N. Engl. J. Med.	324:5:308-17	1991	1986289		W C Greene	W C Greene	W C Greene	Department of Medicine, Howard Hughes Medical Institute, Durham, NC.	NA
Smith MR, Greene WC	Functional analyses of the type I human T-cell leukemia virus tax gene product.	Trans. Assoc. Am. Physicians	104:78-91	1991	1845158		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NA
Kim JH, Kaufman PA, Hanly SM, Rimsky LT, Greene WC	Rex transregulation of human T-cell leukemia virus type II gene expression.	J. Virol.	65:1:405-14	1991	1985205		J H Kim, P A Kaufman, S M Hanly, L T Rimsky, W C Greene	J H Kim	W C Greene	Division of Infectious Diseases, Duke University Medical Center, Durham, North Carolina 27710.	NCI NIH HHS; 5 K11 CA01458-02
Molitor JA, Walker WH, Doerre S, Ballard DW, Greene WC	NF-kappa B: a family of inducible and differentially expressed enhancer-binding proteins in human T cells.	Proc. Natl. Acad. Sci. U.S.A.	87:24:10028-32	1990	2263603		J A Molitor, W H Walker, S Doerre, D W Ballard, W C Greene	J A Molitor	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NIGMS NIH HHS; T32-GM07337
Ballard DW, Walker WH, Doerre S, Sista P, Molitor JA, Dixon EP, Peffer NJ, Hannink M, Greene WC	The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function.	Cell	63:4:803-14	1990	2225078		D W Ballard, W H Walker, S Doerre, P Sista, J A Molitor, E P Dixon, N J Peffer, M Hannink, W C Greene	D W Ballard	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Smith MR, Greene WC	Identification of HTLV-I tax trans-activator mutants exhibiting novel transcriptional phenotypes.	Genes Dev.	4:11:1875-85	1990	2276622		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Rubin LA, Galli F, Greene WC, Nelson DL, Jay G	The molecular basis for the generation of the human soluble interleukin 2 receptor.	Cytokine	2:5:330-6	1990	2103332		L A Rubin, F Galli, W C Greene, D L Nelson, G Jay	L A Rubin	G Jay	Department of Medicine, University of Toronto, Ontario, Canada.	NA
Cullen BR, Greene WC	Functions of the auxiliary gene products of the human immunodeficiency virus type 1.	Virology	178:1:1-5	1990	2202146		B R Cullen, W C Greene	B R Cullen	W C Greene	Howard Hughes Medical Institute, Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.	NA
Kuziel WA, Greene WC	Interleukin-2 and the IL-2 receptor: new insights into structure and function.	J. Invest. Dermatol.	94:6 Suppl:27S-32S	1990	1693645		W A Kuziel, W C Greene	W A Kuziel	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Durham, North Carolina.	NA
Ahmed YF, Hanly SM, Malim MH, Cullen BR, Greene WC	Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action.	Genes Dev.	4:6:1014-22	1990	2116986		Y F Ahmed, S M Hanly, M H Malim, B R Cullen, W C Greene	Y F Ahmed	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Fung MR, Greene WC	The human interleukin-2 receptor: insights into subunit structure and growth signal transduction.	Semin. Immunol.	2:2:119-28	1990	2129904		M R Fung, W C Greene	M R Fung	W C Greene	Howard Hughes Medical Institute, Department of Medicine and Microbiology-Immunology, Duke University Medical Center, Durham, NC 27710.	NA
Mills GB, May C, McGill M, Fung M, Baker M, Sutherland R, Greene WC	Interleukin 2-induced tyrosine phosphorylation. Interleukin 2 receptor beta is tyrosine phosphorylated.	J. Biol. Chem.	265:6:3561-7	1990	2303462		G B Mills, C May, M McGill, M Fung, M Baker, R Sutherland, W C Greene	G B Mills	W C Greene	Oncology Research, Toronto General Hospital, Ontario, Canada.	NA
Greene WC	Regulation of HIV-1 gene expression.	Annu. Rev. Immunol.	8:453-75	1990	2188670		W C Greene	W C Greene	W C Greene	Howard Hughes Medical Institute, Department of Medicine and Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.	NA
Pomerantz JL, Mauxion F, Yoshida M, Greene WC, Sen R	A second sequence element located 3' to the NF-kappa B-binding site regulates IL-2 receptor-alpha gene induction.	J. Immunol.	143:12:4275-81	1989	2687377		J L Pomerantz, F Mauxion, M Yoshida, W C Greene, R Sen	J L Pomerantz	R Sen	Rosenstiel Center, Brandeis University, Waltham, MA 02254-9110.	NIGMS NIH HHS; GM 38925-02
Hammes SR, Dixon EP, Malim MH, Cullen BR, Greene WC	Nef protein of human immunodeficiency virus type 1: evidence against its role as a transcriptional inhibitor.	Proc. Natl. Acad. Sci. U.S.A.	86:23:9549-53	1989	2687884		S R Hammes, E P Dixon, M H Malim, B R Cullen, W C Greene	S R Hammes	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.	NA
Smith MR, Greene WC	The same 50-kDa cellular protein binds to the negative regulatory elements of the interleukin 2 receptor alpha-chain gene and the human immunodeficiency virus type 1 long terminal repeat.	Proc. Natl. Acad. Sci. U.S.A.	86:21:8526-30	1989	2813410		M R Smith, W C Greene	M R Smith	W C Greene	Howard Hughes Medical Institut, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NA
Rimsky L, Dodon MD, Dixon EP, Greene WC	Trans-dominant inactivation of HTLV-I and HIV-1 gene expression by mutation of the HTLV-I Rex transactivator.	Nature	341:6241:453-6	1989	2677743		L Rimsky, M D Dodon, E P Dixon, W C Greene	L Rimsky	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Hanly SM, Rimsky LT, Malim MH, Kim JH, Hauber J, Duc Dodon M, Le SY, Maizel JV, Cullen BR, Greene WC	Comparative analysis of the HTLV-I Rex and HIV-1 Rev trans-regulatory proteins and their RNA response elements.	Genes Dev.	3:10:1534-44	1989	2482226		S M Hanly, L T Rimsky, M H Malim, J H Kim, J Hauber, M Duc Dodon, S Y Le, J V Maizel, B R Cullen, W C Greene	S M Hanly	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Ballard DW, Böhnlein E, Hoffman JA, Bogerd HP, Dixon EP, Franza BR, Greene WC	Activation of the interleukin-2 receptor alpha gene: regulatory role for DNA-protein interactions flanking the kappa B enhancer.	New Biol.	1:1:83-92	1989	2518691		D W Ballard, E Böhnlein, J A Hoffman, H P Bogerd, E P Dixon, B R Franza, W C Greene	D W Ballard	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Cullen BR, Greene WC	Regulatory pathways governing HIV-1 replication.	Cell	58:3:423-6	1989	2569361		B R Cullen, W C Greene	B R Cullen	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Greene WC, Böhnlein E, Ballard DW	HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises.	Immunol. Today	10:8:272-8	1989	2679647		W C Greene, E Böhnlein, D W Ballard	W C Greene	D W Ballard		NA
Böhnlein E, Ballard DW, Bogerd H, Peffer NJ, Lowenthal JW, Greene WC	Induction of interleukin-2 receptor-alpha gene expression is regulated by post-translational activation of kappa B specific DNA binding proteins.	J. Biol. Chem.	264:15:8475-8	1989	2785992		E Böhnlein, D W Ballard, H Bogerd, N J Peffer, J W Lowenthal, W C Greene	E Böhnlein	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Lowenthal JW, Ballard DW, Bogerd H, Böhnlein E, Greene WC	Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins.	J. Immunol.	142:9:3121-8	1989	2785134		J W Lowenthal, D W Ballard, H Bogerd, E Böhnlein, W C Greene	J W Lowenthal	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Durham, North Carolina 27710.	NA
Hoyos B, Ballard DW, Böhnlein E, Siekevitz M, Greene WC	Kappa B-specific DNA binding proteins: role in the regulation of human interleukin-2 gene expression.	Science	244:4903:457-60	1989	2497518		B Hoyos, D W Ballard, E Böhnlein, M Siekevitz, W C Greene	B Hoyos	W C Greene	Mount Sinai Medical Center, Department of Microbiology, New York, NY 10029.	PHS HHS; A127053-01
Lowenthal JW, Ballard DW, Böhnlein E, Greene WC	Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.	Proc. Natl. Acad. Sci. U.S.A.	86:7:2331-5	1989	2494663		J W Lowenthal, D W Ballard, E Böhnlein, W C Greene	J W Lowenthal	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, NC 27710.	NA
Böhnlein E, Siekevitz M, Ballard DW, Lowenthal JW, Rimsky L, Bogérd H, Hoffman J, Wano Y, Franza BR, Greene WC	Stimulation of the human immunodeficiency virus type 1 enhancer by the human T-cell leukemia virus type I tax gene product involves the action of inducible cellular proteins.	J. Virol.	63:4:1578-86	1989	2784507		E Böhnlein, M Siekevitz, D W Ballard, J W Lowenthal, L Rimsky, H Bogérd, J Hoffman, Y Wano, B R Franza, W C Greene	E Böhnlein	W C Greene	Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Ballard DW, Greene WC	HIV-1, HTLV-I and the interleukin-2 receptor: insights into transcriptional control.	Haematol Blood Transfus	32:393-401	1989	2625257		E Böhnlein, J W Lowenthal, Y Wano, B R Franza, D W Ballard, W C Greene	E Böhnlein	W C Greene	Sandoz Forschungsinstitut, Vienna, Austria.	NA
Wano Y, Feinberg M, Hosking JB, Bogerd H, Greene WC	Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth.	Proc. Natl. Acad. Sci. U.S.A.	85:24:9733-7	1988	3059351		Y Wano, M Feinberg, J B Hosking, H Bogerd, W C Greene	Y Wano	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.	NA
Fung MR, Ju G, Greene WC	Co-internalization of the p55 and p70 subunits of the high-affinity human interleukin 2 receptor. Evidence for a stable ternary receptor complex.	J. Exp. Med.	168:5:1923-8	1988	3263468		M R Fung, G Ju, W C Greene	M R Fung	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Rimsky L, Hauber J, Dukovich M, Malim MH, Langlois A, Cullen BR, Greene WC	Functional replacement of the HIV-1 rev protein by the HTLV-1 rex protein.	Nature	335:6192:738-40	1988	3262832		L Rimsky, J Hauber, M Dukovich, M H Malim, A Langlois, B R Cullen, W C Greene	L Rimsky	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Collins L, Tsien WH, Seals C, Hakimi J, Weber D, Bailon P, Hoskings J, Greene WC, Toome V, Ju G	Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor.	Proc. Natl. Acad. Sci. U.S.A.	85:20:7709-13	1988	3051003		L Collins, W H Tsien, C Seals, J Hakimi, D Weber, P Bailon, J Hoskings, W C Greene, V Toome, G Ju	L Collins	G Ju	Department of Molecular Genetics, Hoffmann-La Roche Inc., Nutley, NJ 07110.	NA
Ballard DW, Böhnlein E, Lowenthal JW, Wano Y, Franza BR, Greene WC	HTLV-I tax induces cellular proteins that activate the kappa B element in the IL-2 receptor alpha gene.	Science	241:4873:1652-5	1988	2843985		D W Ballard, E Böhnlein, J W Lowenthal, Y Wano, B R Franza, W C Greene	D W Ballard	W C Greene	Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710.	NA
Froussard P, Chastagner P, Sommé G, Abadie A, Greene W, Thèze J, Longacre S	p55 IL-2 receptor mRNA precursors in murine T lymphocyte nuclei.	J. Immunol.	141:4:1358-64	1988	3135330		P Froussard, P Chastagner, G Sommé, A Abadie, W Greene, J Thèze, S Longacre	P Froussard	S Longacre	Unité d'Immunogénétique Cellulaire, Institut Pasteur, Paris, France.	NA
Böhnlein E, Lowenthal JW, Siekevitz M, Ballard DW, Franza BR, Greene WC	The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV.	Cell	53:5:827-36	1988	2836068		E Böhnlein, J W Lowenthal, M Siekevitz, D W Ballard, B R Franza, W C Greene	E Böhnlein	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.	NA
Lowenthal JW, Böhnlein E, Ballard DW, Greene WC	Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.	Proc. Natl. Acad. Sci. U.S.A.	85:12:4468-72	1988	3132714		J W Lowenthal, E Böhnlein, D W Ballard, W C Greene	J W Lowenthal	W C Greene	Howard Hughes Medical Institute, Department of Medicine, Duke University Medical Center, Durham 27710.	NA
Cullen BR, Podlaski FJ, Peffer NJ, Hosking JB, Greene WC	Sequence requirements for ligand binding and cell surface expression of the Tac antigen, a human interleukin-2 receptor.	J. Biol. Chem.	263:10:4900-6	1988	2832410		B R Cullen, F J Podlaski, N J Peffer, J B Hosking, W C Greene	B R Cullen	W C Greene	Department of Molecular Genetics, Hoffmann-La Roche, Inc., Nutley, New Jersey 07110.	NA
Greene WC	Sarcoidosis and interleukin-2 receptors.	Am. Rev. Respir. Dis.	137:4:757-8	1988	2833139		W C Greene	W C Greene	W C Greene		NA
Zeitz M, Greene WC, Peffer NJ, James SP	Lymphocytes isolated from the intestinal lamina propria of normal nonhuman primates have increased expression of genes associated with T-cell activation.	Gastroenterology	94:3:647-55	1988	3123303		M Zeitz, W C Greene, N J Peffer, S P James	M Zeitz	S P James	Mucosal Immunity Section, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland.	NA
Greene WC, Böhnlein E, Siekevitz M, Franza BR, Lowenthal J	The human interleukin-2 receptor. Recent studies of structure and regulation.	Ann. N. Y. Acad. Sci.	546:116-21	1988	3073691		W C Greene, E Böhnlein, M Siekevitz, B R Franza, J Lowenthal	W C Greene	J Lowenthal	Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710.	NA
Kehrl JH, Dukovich M, Whalen G, Katz P, Fauci AS, Greene WC	Novel interleukin 2 (IL-2) receptor appears to mediate IL-2-induced activation of natural killer cells.	J. Clin. Invest.	81:1:200-5	1988	2826541		J H Kehrl, M Dukovich, G Whalen, P Katz, A S Fauci, W C Greene	J H Kehrl	W C Greene	Laboratory of Immunoregulation, National Institutes of Allergy and Infectious Diseases, Bethesda, Maryland 20892.	NIAID NIH HHS; AI24636
Greene WC, Wano YJ, Dukovich M	New insights into the structure of high-affinity interleukin-2 receptors.	Recent Prog. Horm. Res.	44:141-55	1988	3064206		W C Greene, Y J Wano, M Dukovich	W C Greene	M Dukovich		NA
Siekevitz M, Josephs SF, Dukovich M, Peffer N, Wong-Staal F, Greene WC	Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.	Science	238:4833:1575-8	1987	2825351		M Siekevitz, S F Josephs, M Dukovich, N Peffer, F Wong-Staal, W C Greene	M Siekevitz	W C Greene	Howard Hughes Medical Institute, Duke University School of Medicine, Durham, NC 27710.	NA
Rubin LA, Hoekzema GS, Nelson DL, Greene WC, Jay G	Reconstitution of a functional interleukin 2 receptor in a nonlymphoid cell.	J. Immunol.	139:7:2355-60	1987	2821112		L A Rubin, G S Hoekzema, D L Nelson, W C Greene, G Jay	L A Rubin	G Jay	Laboratory of Molecular Virology, National Cancer Institute, Bethesda, MD 20892.	NA
Lowenthal JW, Greene WC	Contrasting interleukin 2 binding properties of the alpha (p55) and beta (p70) protein subunits of the human high-affinity interleukin 2 receptor.	J. Exp. Med.	166:4:1156-61	1987	3116145		J W Lowenthal, W C Greene	J W Lowenthal	W C Greene	Howard Hughes Medical Institute, Department of Internal Medicine, Duke University School of Medicine, Durham, North Carolina 27710.	NA
Greene WC	The human interleukin-2 receptor: a molecular and biochemical analysis of structure and function.	Clin Res	35:5:439-50	1987	2889557		W C Greene	W C Greene	W C Greene		NA
Bich-Thuy LT, Dukovich M, Peffer NJ, Fauci AS, Kehrl JH, Greene WC	Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.	J. Immunol.	139:5:1550-6	1987	3040856		L T Bich-Thuy, M Dukovich, N J Peffer, A S Fauci, J H Kehrl, W C Greene	L T Bich-Thuy	W C Greene		NA
Wano Y, Hattori T, Matsuoka M, Takatsuki K, Chua AO, Gubler U, Greene WC	Interleukin 1 gene expression in adult T cell leukemia.	J. Clin. Invest.	80:3:911-6	1987	2887587		Y Wano, T Hattori, M Matsuoka, K Takatsuki, A O Chua, U Gubler, W C Greene	Y Wano	W C Greene		NA
Siekevitz M, Feinberg MB, Holbrook N, Wong-Staal F, Greene WC	Activation of interleukin 2 and interleukin 2 receptor (Tac) promoter expression by the trans-activator (tat) gene product of human T-cell leukemia virus, type I.	Proc. Natl. Acad. Sci. U.S.A.	84:15:5389-93	1987	3037548		M Siekevitz, M B Feinberg, N Holbrook, F Wong-Staal, W C Greene	M Siekevitz	W C Greene		NA
Dukovich M, Wano Y, Le thi Bich Thuy P, Katz BR, Cullen JH, Kehrl WC	A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors.	Nature	327:6122:518-22		3108674		M Dukovich, Y Wano, P Le thi Bich Thuy, B R Katz, J H Cullen, W C Kehrl	M Dukovich	 Greene		NA
Holter W, Goldman CK, Casabo L, Nelson DL, Greene WC, Waldmann TA	Expression of functional IL 2 receptors by lipopolysaccharide and interferon-gamma stimulated human monocytes.	J. Immunol.	138:9:2917-22	1987	3106493		W Holter, C K Goldman, L Casabo, D L Nelson, W C Greene, T A Waldmann	W Holter	T A Waldmann		NA
Robb RJ, Greene WC	Internalization of interleukin 2 is mediated by the beta chain of the high-affinity interleukin 2 receptor.	J. Exp. Med.	165:4:1201-6	1987	3031195		R J Robb, W C Greene	R J Robb	W C Greene		NA
Robb RJ, Rusk CM, Yodoi J, Greene WC	Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.	Proc. Natl. Acad. Sci. U.S.A.	84:7:2002-6	1987	3031660		R J Robb, C M Rusk, J Yodoi, W C Greene	R J Robb	W C Greene		NA
Wano Y, Cullen BR, Svetlik PA, Peffer NJ, Greene WC	Reconstitution of high affinity IL-2 receptor expression in a human T-cell line using a retroviral cDNA expression vector.	Mol. Biol. Med.	4:2:95-109	1987	3114593		Y Wano, B R Cullen, P A Svetlik, N J Peffer, W C Greene	Y Wano	W C Greene		NA
Bernard O, Fazekas de St Groth B, Ullrich A, Green W, Schlessinger J	High-affinity interleukin 2 binding by an oncogenic hybrid interleukin 2-epidermal growth factor receptor molecule.	Proc. Natl. Acad. Sci. U.S.A.	84:8:2125-9	1987	3104909		O Bernard, B Fazekas de St Groth, A Ullrich, W Green, J Schlessinger	O Bernard	J Schlessinger		NA
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA	Trans-activator gene of HTLV-II: interpretation.	Science	235:4792:1073	1987	3029865		W C Greene, W J Leonard, Y Wano, P B Svetlik, N J Peffer, J G Sodroski, C A Rosen, W C Goh, W A Haseltine	W C Greene	W A Haseltine		NA
Greene WC, Leonard WJ	Human interleukin 2 receptor (Tac antigen).	Meth. Enzymol.	150:682-700	1987	3123879		W C Greene, W J Leonard	W C Greene	W J Leonard		NA
Greene WC	An overview of the human interleukin-2 receptor: molecular, biochemical, and functional properties.	Cancer Invest.	5:4:369-76	1987	2889515		W C Greene	W C Greene	W C Greene	Howard Hughes Medical Institute, Duke University School of Medicine, Durham, North Carolina 27710.	NA
Chanda PK, Chen GF, Baine Y, Leonard WJ, Greene WC, Chang TW, Chang NT	Expression of human interleukin-2 receptor cDNA in E. coli.	Biochem. Biophys. Res. Commun.	141:2:804-11	1986	3026392		P K Chanda, G F Chen, Y Baine, W J Leonard, W C Greene, T W Chang, N T Chang	P K Chanda	N T Chang		NA
Neckers LM, Bauer S, McGlennen RC, Trepel JB, Rao K, Greene WC	Diltiazem inhibits transferrin receptor expression and causes G1 arrest in normal and neoplastic T cells.	Mol. Cell. Biol.	6:12:4244-50	1986	2432398		L M Neckers, S Bauer, R C McGlennen, J B Trepel, K Rao, W C Greene	L M Neckers	W C Greene		NA
Greene WC	Characterization of the human interleukin 2 receptor at the DNA, RNA, and protein level.	Immunobiology	172:3-5:357-64	1986	3100432		W C Greene	W C Greene	W C Greene		NA
Greene WC, Depper JM, Krönke M, Leonard WJ	The human interleukin-2 receptor: analysis of structure and function.	Immunol. Rev.	92:29-48	1986	3091481		W C Greene, J M Depper, M Krönke, W J Leonard	W C Greene	W J Leonard		NA
Krönke M, Schlick E, Waldmann TA, Vitetta ES, Greene WC	Selective killing of human T-lymphotropic virus-I infected leukemic T-cells by monoclonal anti-interleukin 2 receptor antibody-ricin A chain conjugates: potentiation by ammonium chloride and monensin.	Cancer Res.	46:7:3295-8	1986	3011246		M Krönke, E Schlick, T A Waldmann, E S Vitetta, W C Greene	M Krönke	W C Greene		NA
Treiger BF, Leonard WJ, Svetlik P, Rubin LA, Nelson DL, Greene WC	A secreted form of the human interleukin 2 receptor encoded by an "anchor minus" cDNA.	J. Immunol.	136:11:4099-105	1986	3084654		B F Treiger, W J Leonard, P Svetlik, L A Rubin, D L Nelson, W C Greene	B F Treiger	W C Greene		NA
Greene WC, Leonard WJ, Wano Y, Svetlik PB, Peffer NJ, Sodroski JG, Rosen CA, Goh WC, Haseltine WA	Trans-activator gene of HTLV-II induces IL-2 receptor and IL-2 cellular gene expression.	Science	232:4752:877-80	1986	3010456		W C Greene, W J Leonard, Y Wano, P B Svetlik, N J Peffer, J G Sodroski, C A Rosen, W C Goh, W A Haseltine	W C Greene	W A Haseltine		NCI NIH HHS; CA40658
Weissman AM, Harford JB, Svetlik PB, Leonard WL, Depper JM, Waldmann TA, Greene WC, Klausner RD	Only high-affinity receptors for interleukin 2 mediate internalization of ligand.	Proc. Natl. Acad. Sci. U.S.A.	83:5:1463-6	1986	3081898		A M Weissman, J B Harford, P B Svetlik, W L Leonard, J M Depper, T A Waldmann, W C Greene, R D Klausner	A M Weissman	R D Klausner		NA
Greene WC, Leonard WJ	The human interleukin-2 receptor.	Annu. Rev. Immunol.	4:69-95	1986	3011033		W C Greene, W J Leonard	W C Greene	W J Leonard		NA
Greene WC, Leonard WJ, Depper JM	Growth of human T lymphocytes: an analysis of interleukin 2 and its cellular receptor.	Prog Hematol	14:283-301	1986	2418464		W C Greene, W J Leonard, J M Depper	W C Greene	J M Depper		NA
Waldmann TA, Korsmeyer SJ, Greene WC	The arrangement of immunoglobulin, T cell antigen receptor, and interleukin 2 receptor genes in human lymphoid neoplasms.	Symp Fundam Cancer Res	38:63-78	1986	3489263		T A Waldmann, S J Korsmeyer, W C Greene	T A Waldmann	W C Greene		NA
Greene WC, Depper JM, Krönke M, Leonard WJ	The human interleukin-2 receptor: role in normal T-cell growth and association with HTLV-I-induced T-cell leukemia.	Cold Spring Harb. Symp. Quant. Biol.	51 Pt 2:731-7	1986	2884072		W C Greene, J M Depper, M Krönke, W J Leonard	W C Greene	W J Leonard		NA
Leonard WJ, Depper JM, Kanehisa M, Krönke M, Peffer NJ, Svetlik PB, Sullivan M, Greene WC	Structure of the human interleukin-2 receptor gene.	Science	230:4726:633-9	1985	2996141		W J Leonard, J M Depper, M Kanehisa, M Krönke, N J Peffer, P B Svetlik, M Sullivan, W C Greene	W J Leonard	W C Greene		NA
Reed JC, Greene WC, Hoover RG, Nowell PC	Monoclonal antibody OKT11A inhibits and recombinant interleukin 2 (IL 2) augments expression of IL 2 receptors at a pretranslational level.	J. Immunol.	135:4:2478-82	1985	3928749		J C Reed, W C Greene, R G Hoover, P C Nowell	J C Reed	P C Nowell		NCI NIH HHS; CA-36403
Waldmann TA, Longo DL, Leonard WJ, Depper JM, Thompson CB, Krönke M, Goldman CK, Sharrow S, Bongiovanni K, Greene WC	Interleukin 2 receptor (Tac antigen) expression in HTLV-I-associated adult T-cell leukemia.	Cancer Res.	45:9 Suppl:4559s-4562s	1985	2990687		T A Waldmann, D L Longo, W J Leonard, J M Depper, C B Thompson, M Krönke, C K Goldman, S Sharrow, K Bongiovanni, W C Greene	T A Waldmann	W C Greene		NA
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA	Isolation and expression of complementary DNAs encoding the human interleukin 2 receptor.	Cancer Res.	45:9 Suppl:4563s-4567s	1985	2990688		W C Greene, J M Depper, G R Crabtree, S Rudikoff, J Pumphrey, R J Robb, M Krönke, P Svetlik, N J Peffer, T A Waldmann	W C Greene	T A Waldmann		NA
Leonard WJ, Krönke M, Peffer NJ, Depper JM, Greene WC	Interleukin 2 receptor gene expression in normal human T lymphocytes.	Proc. Natl. Acad. Sci. U.S.A.	82:18:6281-5	1985	3929255		W J Leonard, M Krönke, N J Peffer, J M Depper, W C Greene	W J Leonard	W C Greene		NA
Lane HC, Depper JM, Greene WC, Whalen G, Waldmann TA, Fauci AS	Qualitative analysis of immune function in patients with the acquired immunodeficiency syndrome. Evidence for a selective defect in soluble antigen recognition.	N. Engl. J. Med.	313:2:79-84	1985	2582258		H C Lane, J M Depper, W C Greene, G Whalen, T A Waldmann, A S Fauci	H C Lane	A S Fauci		NA
Greene WC, Robb RJ, Svetlik PB, Rusk CM, Depper JM, Leonard WJ	Stable expression of cDNA encoding the human interleukin 2 receptor in eukaryotic cells.	J. Exp. Med.	162:1:363-8	1985	2989411		W C Greene, R J Robb, P B Svetlik, C M Rusk, J M Depper, W J Leonard	W C Greene	W J Leonard		NA
Leonard WJ, Donlon TA, Lebo RV, Greene WC	Localization of the gene encoding the human interleukin-2 receptor on chromosome 10.	Science	228:4707:1547-9	1985	3925551		W J Leonard, T A Donlon, R V Lebo, W C Greene	W J Leonard	W C Greene		NA
Krönke M, Leonard WJ, Depper JM, Greene WC	Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia.	Science	228:4704:1215-7	1985	2988127		M Krönke, W J Leonard, J M Depper, W C Greene	M Krönke	W C Greene		NA
Depper JM, Leonard WJ, Drogula C, Krönke M, Waldmann TA, Greene WC	Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.	Proc. Natl. Acad. Sci. U.S.A.	82:12:4230-4	1985	2987968		J M Depper, W J Leonard, C Drogula, M Krönke, T A Waldmann, W C Greene	J M Depper	W C Greene		NA
Miller J, Malek TR, Leonard WJ, Greene WC, Shevach EM, Germain RN	Nucleotide sequence and expression of a mouse interleukin 2 receptor cDNA.	J. Immunol.	134:6:4212-7	1985	3921620		J Miller, T R Malek, W J Leonard, W C Greene, E M Shevach, R N Germain	J Miller	R N Germain		NA
Krönke M, Leonard WJ, Depper JM, Greene WC	Sequential expression of genes involved in human T lymphocyte growth and differentiation.	J. Exp. Med.	161:6:1593-8	1985	2989408		M Krönke, W J Leonard, J M Depper, W C Greene	M Krönke	W C Greene		NA
Krönke M, Depper JM, Leonard WJ, Vitetta ES, Waldmann TA, Greene WC	Adult T cell leukemia: a potential target for ricin A chain immunotoxins.	Blood	65:6:1416-21	1985	2986744		M Krönke, J M Depper, W J Leonard, E S Vitetta, T A Waldmann, W C Greene	M Krönke	W C Greene		NCI NIH HHS; CA-28149
Leonard WJ, Depper JM, Krönke M, Robb RJ, Waldmann TA, Greene WC	The human receptor for T-cell growth factor. Evidence for variable post-translational processing, phosphorylation, sulfation, and the ability of precursor forms of the receptor to bind T-cell growth factor.	J. Biol. Chem.	260:3:1872-80	1985	2981876		W J Leonard, J M Depper, M Krönke, R J Robb, T A Waldmann, W C Greene	W J Leonard	W C Greene		NA
Greene WC, Robb RJ	Receptors for T-cell growth factor: structure, function and expression on normal and neoplastic cells.	Contemp Top Mol Immunol	10:1-34	1985	2983931		W C Greene, R J Robb	W C Greene	R J Robb		NA
Greene WC, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik P, Peffer NJ, Waldmann TA	Molecular cloning of cDNA for the human interleukin-2 receptor.	Haematol Blood Transfus	29:388-95	1985	2993133		W C Greene, J M Depper, G R Crabtree, S Rudikoff, J Pumphrey, R J Robb, M Krönke, P Svetlik, N J Peffer, T A Waldmann	W C Greene	T A Waldmann		NA
Greene WC, Depper JM, Krönke M, Leonard WJ	The human interleukin-2 receptor.	J. Cell Sci. Suppl.	3:97-106	1985	3938983		W C Greene, J M Depper, M Krönke, W J Leonard	W C Greene	W J Leonard		NA
Reed JC, Robb RJ, Greene WC, Nowell PC	Effect of wheat germ agglutinin on the interleukin pathway of human T lymphocyte activation.	J. Immunol.	134:1:314-23	1985	3917278		J C Reed, R J Robb, W C Greene, P C Nowell	J C Reed	P C Nowell		NCI NIH HHS; CA-12779
Depper JM, Leonard WJ, Drogula CL, Krönke M, Waldmann TA, Greene WC	Activators of protein kinase C and 5-azacytidine induce IL-2 receptor expression on human T lymphocytes.	J. Cell. Biochem.	27:3:267-76	1985	2580852		J M Depper, W J Leonard, C L Drogula, M Krönke, T A Waldmann, W C Greene	J M Depper	W C Greene		NA
Korsmeyer SJ, Greene WC, Waldmann TA	Cellular origin of hairy cell leukemia: malignant B cells that express receptors for T cell growth factor.	Semin. Oncol.	11:4:394-400	1984	6438801		S J Korsmeyer, W C Greene, T A Waldmann	S J Korsmeyer	T A Waldmann		NA
Depper JM, Leonard WJ, Krönke M, Noguchi PD, Cunningham RE, Waldmann TA, Greene WC	Regulation of interleukin 2 receptor expression: effects of phorbol diester, phospholipase C, and reexposure to lectin or antigen.	J. Immunol.	133:6:3054-61	1984	6092466		J M Depper, W J Leonard, M Krönke, P D Noguchi, R E Cunningham, T A Waldmann, W C Greene	J M Depper	W C Greene		NA
Waldmann TA, Goldman CK, Robb RJ, Depper JM, Leonard WJ, Sharrow SO, Bongiovanni KF, Korsmeyer SJ, Greene WC	Expression of interleukin 2 receptors on activated human B cells.	J. Exp. Med.	160:5:1450-66	1984	6092511		T A Waldmann, C K Goldman, R J Robb, J M Depper, W J Leonard, S O Sharrow, K F Bongiovanni, S J Korsmeyer, W C Greene	T A Waldmann	W C Greene		NA
Depper JM, Leonard WJ, Krönke M, Waldmann TA, Greene WC	Augmented T cell growth factor receptor expression in HTLV-1-infected human leukemic T cells.	J. Immunol.	133:4:1691-5	1984	6088625		J M Depper, W J Leonard, M Krönke, T A Waldmann, W C Greene	J M Depper	W C Greene		NA
Leonard WJ, Depper JM, Crabtree GR, Rudikoff S, Pumphrey J, Robb RJ, Krönke M, Svetlik PB, Peffer NJ, Waldmann TA	Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.	Nature	311:5987:626-31		6090948		W J Leonard, J M Depper, G R Crabtree, S Rudikoff, J Pumphrey, R J Robb, M Krönke, P B Svetlik, N J Peffer, T A Waldmann	W J Leonard	T A Waldmann		NA
Robb RJ, Greene WC, Rusk CM	Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen.	J. Exp. Med.	160:4:1126-46	1984	6090574		R J Robb, W C Greene, C M Rusk	R J Robb	C M Rusk		NA
Krönke M, Leonard WJ, Depper JM, Arya SK, Wong-Staal F, Gallo RC, Waldmann TA, Greene WC	Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.	Proc. Natl. Acad. Sci. U.S.A.	81:16:5214-8	1984	6332315		M Krönke, W J Leonard, J M Depper, S K Arya, F Wong-Staal, R C Gallo, T A Waldmann, W C Greene	M Krönke	W C Greene		NA
Greene WC, Robb RJ, Depper JM, Leonard WJ, Drogula C, Svetlik PB, Wong-Staal F, Gallo RC, Waldmann TA	Phorbol diester induces expression of Tac antigen on human acute T lymphocytic leukemic cells.	J. Immunol.	133:2:1042-7	1984	6330200		W C Greene, R J Robb, J M Depper, W J Leonard, C Drogula, P B Svetlik, F Wong-Staal, R C Gallo, T A Waldmann	W C Greene	T A Waldmann		NA
Waldmann TA, Greene WC, Sarin PS, Saxinger C, Blayney DW, Blattner WA, Goldman CK, Bongiovanni K, Sharrow S, Depper JM	Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sézary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor.	J. Clin. Invest.	73:6:1711-8	1984	6327770		T A Waldmann, W C Greene, P S Sarin, C Saxinger, D W Blayney, W A Blattner, C K Goldman, K Bongiovanni, S Sharrow, J M Depper	T A Waldmann	J M Depper		NA
Waldmann TA, Leonard WJ, Depper JM, Krönke M, Goldman CK, Oh T, Greene WC	Interleukin-2 receptor expression in retrovirus associated adult T-cell leukemia.	Int. Symp. Princess Takamatsu Cancer Res. Fund	15:259-68	1984	6100644		T A Waldmann, W J Leonard, J M Depper, M Krönke, C K Goldman, T Oh, W C Greene	T A Waldmann	W C Greene		NA
Waldmann TA, Goldman CK, Leonard WJ, Depper JM, Robb RJ, Korsmeyer SJ, Greene WC	Interleukin-2 receptors on activated malignant and normal B-cells.	Curr. Top. Microbiol. Immunol.	113:96-101	1984	6236954		T A Waldmann, C K Goldman, W J Leonard, J M Depper, R J Robb, S J Korsmeyer, W C Greene	T A Waldmann	W C Greene		NA
Lipkowitz S, Greene WC, Rubin AL, Novogrodsky A, Stenzel KH	Expression of receptors for interleukin 2: Role in the commitment of T lymphocytes to proliferate.	J. Immunol.	132:1:31-7	1984	6418801		S Lipkowitz, W C Greene, A L Rubin, A Novogrodsky, K H Stenzel	S Lipkowitz	K H Stenzel		NA
Littman BH, Muchmore AV, Steinberg AD, Greene WC	Monoclonal lupus autoantibody secretion by human-human hybridomas. Selection of hybrids by conventional and novel techniques.	J. Clin. Invest.	72:6:1987-94	1983	6605979		B H Littman, A V Muchmore, A D Steinberg, W C Greene	B H Littman	W C Greene		NIADDK NIH HHS; K04 AM 00336
Leonard WJ, Depper JM, Robb RJ, Waldmann TA, Greene WC	Characterization of the human receptor for T-cell growth factor.	Proc. Natl. Acad. Sci. U.S.A.	80:22:6957-61	1983	6417659		W J Leonard, J M Depper, R J Robb, T A Waldmann, W C Greene	W J Leonard	W C Greene		NA
Lando Z, Sarin P, Megson M, Greene WC, Waldman TA, Gallo RC, Broder S	Association of human T-cell leukaemia/lymphoma virus with the Tac antigen marker for the human T-cell growth factor receptor.	Nature	305:5936:733-6		6195529		Z Lando, P Sarin, M Megson, W C Greene, T A Waldman, R C Gallo, S Broder	Z Lando	S Broder		NA
Robb RJ, Greene WC	Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen.	J. Exp. Med.	158:4:1332-7	1983	6413637		R J Robb, W C Greene	R J Robb	W C Greene		NA
Depper JM, Leonard WJ, Robb RJ, Waldmann TA, Greene WC	Blockade of the interleukin-2 receptor by anti-Tac antibody: inhibition of human lymphocyte activation.	J. Immunol.	131:2:690-6	1983	6408186		J M Depper, W J Leonard, R J Robb, T A Waldmann, W C Greene	J M Depper	W C Greene		NA
Korsmeyer SJ, Greene WC, Cossman J, Hsu SM, Jensen JP, Neckers LM, Marshall SL, Bakhshi A, Depper JM, Leonard WJ, Jaffe ES, Waldmann TA	Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.	Proc. Natl. Acad. Sci. U.S.A.	80:14:4522-6	1983	6192435		S J Korsmeyer, W C Greene, J Cossman, S M Hsu, J P Jensen, L M Neckers, S L Marshall, A Bakhshi, J M Depper, W J Leonard, E S Jaffe, T A Waldmann	S J Korsmeyer	T A Waldmann		NA
Koretzky GA, Daniele RP, Greene WC, Nowell PC	Evidence for an interleukin-independent pathway for human lymphocyte activation.	Proc. Natl. Acad. Sci. U.S.A.	80:11:3444-7	1983	6407014		G A Koretzky, R P Daniele, W C Greene, P C Nowell	G A Koretzky	P C Nowell		NCI NIH HHS; CA-15822
Cossman J, Neckers LM, Leonard WJ, Greene WC	Polymorphonuclear neutrophils express the common acute lymphoblastic leukemia antigen.	J. Exp. Med.	157:3:1064-9	1983	6220104		J Cossman, L M Neckers, W J Leonard, W C Greene	J Cossman	W C Greene		NA
Blaese RM, Tosato G, Greene WC, Fleisher TA, Muchmore AV	The role of cell surface lectin--carbohydrate interactions in cellular recognition, cooperation, and regulation.	Am J Pediatr Hematol Oncol	5:2:199-206	1983	6193722		R M Blaese, G Tosato, W C Greene, T A Fleisher, A V Muchmore	R M Blaese	A V Muchmore		NA
Greene WC, Depper JM, Leonard WJ, Fleisher TA, Waldmann TA	Construction of human suppressor T cell hybridomas.	Lymphokine Res.	2:2:53-60	1983	6236341		W C Greene, J M Depper, W J Leonard, T A Fleisher, T A Waldmann	W C Greene	T A Waldmann		NA
Leonard WJ, Depper JM, Uchiyama T, Smith KA, Waldmann TA, Greene WC	A monoclonal antibody that appears to recognize the receptor for human T-cell growth factor; partial characterization of the receptor.	Nature	300:5889:267-9	1982	6815536		W J Leonard, J M Depper, T Uchiyama, K A Smith, T A Waldmann, W C Greene	W J Leonard	W C Greene		NA
Greene WC, Fleisher TA, Nelson DL, Waldmann TA	Production of human suppressor T cell hybridomas.	J. Immunol.	129:5:1986-92	1982	6214585		W C Greene, T A Fleisher, D L Nelson, T A Waldmann	W C Greene	T A Waldmann		NA
Fleisher TA, Attallah AM, Tosato G, Blaese RM, Greene WC	Interferon-mediated inhibition of human polyclonal immunoglobulin synthesis.	J. Immunol.	129:3:1099-103	1982	6179992		T A Fleisher, A M Attallah, G Tosato, R M Blaese, W C Greene	T A Fleisher	W C Greene		NA
Greene WC, Fleisher TA, Depper JM, Leonard WJ, Stanton GJ, Waldmann TA	Characterization of a soluble suppressor of human B cell function produced by a continuous human suppressor T cell line. II. Evidence for suppression through a direct action of CTC-SISS-B on human B cells.	J. Immunol.	129:3:1120-3	1982	6213708		W C Greene, T A Fleisher, J M Depper, W J Leonard, G J Stanton, T A Waldmann	W C Greene	T A Waldmann		NA
Greene WC, Goldman CK, Marshall ST, Fleisher TA, Waldmann TA	Stimulation of immunoglobulin biosynthesis in human B cells by wheat germ agglutinin. I. Evidence that WGA can produce both a positive and negative signal for activation of human lymphocytes.	J. Immunol.	127:2:799-804	1981	6265558		W C Greene, C K Goldman, S T Marshall, T A Fleisher, T A Waldmann	W C Greene	T A Waldmann		NA
Fleisher TA, Greene WC, Uchiyama T, Goldman CK, Nelson DL, Blaese RM, Waldmann TA	Characterization of a soluble suppressor of human B cell immunoglobulin biosynthesis produced by a continuous human suppressor T cell line.	J. Exp. Med.	154:1:156-67	1981	6454754		T A Fleisher, W C Greene, T Uchiyama, C K Goldman, D L Nelson, R M Blaese, T A Waldmann	T A Fleisher	T A Waldmann		NA
Fleisher TA, Greene WC, Blaese RM, Waldmann TA	Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. II. Characterization of a soluble suppressor of B cell immunoglobulin production.	J. Immunol.	126:3:1192-7	1981	6450804		T A Fleisher, W C Greene, R M Blaese, T A Waldmann	T A Fleisher	T A Waldmann		NA
Greene WC, Fleisher TA, Waldmann TA	Soluble suppressor supernatants elaborated by concanavalin A-activated human mononuclear cells. I. Characterization of a soluble suppressor T cell proliferation.	J. Immunol.	126:3:1185-91	1981	6450803		W C Greene, T A Fleisher, T A Waldmann	W C Greene	T A Waldmann		NA
Greene WC, Fleisher TA, Waldmann TA	Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. I. Suggestive evidence for a surface "suppressor" receptor in human lymphocytes.	J. Immunol.	126:2:580-6	1981	6778919		W C Greene, T A Fleisher, T A Waldmann	W C Greene	T A Waldmann		NA
Greene WC, Waldmann TA	Inhibition of human lymphocyte proliferation by the nonmitogenic lectin wheat germ agglutinin.	J. Immunol.	124:6:2979-87	1980	6966300		W C Greene, T A Waldmann	W C Greene	T A Waldmann		NA
Parker CW, Greene WC, MacDonald HH	Cytochalasin binding in lymphocytes and polymorphonuclear leukocytes.	Exp. Cell Res.	103:1:99-108	1976	991953		C W Parker, W C Greene, H H MacDonald	C W Parker	H H MacDonald		NA
Greene WC, Parker CM, Parker CW	Cytochalasin sensitive structures and lymphocyte activation.	Exp. Cell Res.	103:1:109-17	1976	186286		W C Greene, C M Parker, C W Parker	W C Greene	C W Parker		NA
Greene WC, Parker CM, Parker CW	Colchicine-sensitive structures and lymphocyte activation.	J. Immunol.	117:3:1015-22	1976	956646		W C Greene, C M Parker, C W Parker	W C Greene	C W Parker		NA
Greene WC, Parker CM, Parker CW	Opposing effects of mitogenic and nonmitogenic lectins on lymphocyte activation. Evidence that wheat germ agglutinin produces a negative signal.	J. Biol. Chem.	251:13:4017-25	1976	932019		W C Greene, C M Parker, C W Parker	W C Greene	C W Parker		NA
Greene WC, Parker CM, Parker CW	Calcium and lymphocyte activation.	Cell. Immunol.	25:1:74-89	1976	183895		W C Greene, C M Parker, C W Parker	W C Greene	C W Parker		NA
Atkinson JP, Greene WC, McNearney TA, Parker CW	Studies on the stimulation of cAMP metabolism in human lymphocytes by latex polymers.	Exp. Cell Res.	99:2:395-407	1976	178514		J P Atkinson, W C Greene, T A McNearney, C W Parker	J P Atkinson	C W Parker		NA
Parker CW, Dankner RE, Falkenhein SF, Greene WC	Suggestive evidence for both stimulatory and inhibitory domains on human lymphocytes, as indicated by phospholipid turnover studies with wheat germ agglutinin and other lectins.	Immunol. Commun.	5:1-2:13-25	1976	181319		C W Parker, R E Dankner, S F Falkenhein, W C Greene	C W Parker	W C Greene		NA
Greene WC, Parker CW	A role for cytochalasin-sensitive proteins in the regulation of calcium transport in activated human lymphocytes.	Biochem. Biophys. Res. Commun.	65:2:456-63	1975	167774		W C Greene, C W Parker	W C Greene	C W Parker		NA
Sullivan TJ, Greene WC, Parker CW	Concanavalin A-induced histamine release from normal rat mast cells.	J. Immunol.	115:1:278-82	1975	50352		T J Sullivan, W C Greene, C W Parker	T J Sullivan	C W Parker		NA
Peterson DT, Greene WC, Reaven GM	Effect of experimental diabetes mellitus on kidney ribosomal protein synthesis.	Diabetes	20:10:649-54	1971	5110696		D T Peterson, W C Greene, G M Reaven	D T Peterson	G M Reaven		NA
Charo IF	Blinding the monocytes to protect the heart.	Circulation	127:20:2006-8	2013	23616628		Israel F Charo	Israel F Charo	Israel F Charo	J. David Gladstone Institutes, 1650 Owens St, San Francisco, CA 94158. icharo@gladstone.ucsf.edu.	NA
Varvel NH, Grathwohl SA, Baumann F, Liebig C, Bosch A, Brawek B, Thal DR, Charo IF, Heppner FL, Aguzzi A, Garaschuk O, Ransohoff RM, Jucker M	Microglial repopulation model reveals a robust homeostatic process for replacing CNS myeloid cells.	Proc. Natl. Acad. Sci. U.S.A.	109:44:18150-5	2012	23071306		Nicholas H Varvel, Stefan A Grathwohl, Frank Baumann, Christian Liebig, Andrea Bosch, Bianca Brawek, Dietmar R Thal, Israel F Charo, Frank L Heppner, Adriano Aguzzi, Olga Garaschuk, Richard M Ransohoff, Mathias Jucker	Nicholas H Varvel	Mathias Jucker	German Center for Neurodegenerative Diseases, DZNE, and Department of Cellular Neurology, Hertie Institute for Clinical Brain Research, University of Tuebingen, 72076 Tuebingen, Germany. nicholas.varvel@dzne.de	NHLBI NIH HHS; R01 HL102475
Sullivan TJ, Dairaghi DJ, Krasinski A, Miao Z, Wang Y, Zhao BN, Baumgart T, Berahovich R, Ertl LS, Pennell A, Seitz L, Miao S, Ungashe S, Wei Z, Johnson D, Boring L, Tsou CL, Charo IF, Bekker P, Schall TJ, Jaen JC	Characterization of CCX140-B, an orally bioavailable antagonist of the CCR2 chemokine receptor, for the treatment of type 2 diabetes and associated complications.	J. Pharmacol. Exp. Ther.		2012	22378937		Timothy J Sullivan, Daniel J Dairaghi, Antoni Krasinski, Zhenhua Miao, Yu Wang, Bin N Zhao, Trageen Baumgart, Rob Berahovich, Linda S Ertl, Andrew Pennell, Lisa Seitz, Shichang Miao, Solomon Ungashe, Zheng Wei, Dan Johnson, Landin Boring, Chia-Lin Tsou, Israel F Charo, Pirow Bekker, Thomas J Schall, Juan C Jaen	Timothy J Sullivan	Juan C Jaen		NA
Mizutani M, Pino PA, Saederup N, Charo IF, Ransohoff RM, Cardona AE	The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood.	J. Immunol.	188:1:29-36	2012	22079990		Makiko Mizutani, Paula A Pino, Noah Saederup, Israel F Charo, Richard M Ransohoff, Astrid E Cardona	Makiko Mizutani	Astrid E Cardona	Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.	NINDS NIH HHS; R01NS32151
Lewis KL, Caton ML, Bogunovic M, Greter M, Grajkowska LT, Ng D, Klinakis A, Charo IF, Jung S, Gommerman JL, Ivanov II, Liu K, Merad M, Reizis B	Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine.	Immunity	35:5:780-91	2011	22018469		Kanako L Lewis, Michele L Caton, Milena Bogunovic, Melanie Greter, Lucja T Grajkowska, Dennis Ng, Apostolos Klinakis, Israel F Charo, Steffen Jung, Jennifer L Gommerman, Ivaylo I Ivanov, Kang Liu, Miriam Merad, Boris Reizis	Kanako L Lewis	Boris Reizis	Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.	NICHD NIH HHS; T32 HD055165-05
Charo IF, Taub R	Anti-inflammatory therapeutics for the treatment of atherosclerosis.	Nat Rev Drug Discov	10:5:365-76	2011	21532566		Israel F Charo, Rebecca Taub	Israel F Charo	Rebecca Taub	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street #149, San Francisco, California 94158, USA. icharo@gladstone.ucsf.edu	NHLBI NIH HHS; R01 HL052773
Sonoda KH, Yoshimura T, Egashira K, Charo IF, Ishibashi T	Neutrophil-dominant experimental autoimmune uveitis in CC-chemokine receptor 2 knockout mice.	Acta Ophthalmol	89:2:e180-8	2011	20584001		Koh-Hei Sonoda, Takeru Yoshimura, Kensuke Egashira, Israel F Charo, Tatsuro Ishibashi	Koh-Hei Sonoda	Tatsuro Ishibashi	Department of Ophthalmology, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan. sonodak@med.kyushu-u.ac.jp	NA
Islam SA, Chang DS, Colvin RA, Byrne MH, McCully ML, Moser B, Lira SA, Charo IF, Luster AD	Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ T(H)2 cells.	Nat. Immunol.	12:2:167-77	2011	21217759		Sabina A Islam, Daniel S Chang, Richard A Colvin, Mike H Byrne, Michelle L McCully, Bernhard Moser, Sergio A Lira, Israel F Charo, Andrew D Luster	Sabina A Islam	Andrew D Luster	Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.	NIAID NIH HHS; R37 AI040618-15
Saederup N, Cardona AE, Croft K, Mizutani M, Cotleur AC, Tsou CL, Ransohoff RM, Charo IF	Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice.	PLoS ONE	5:10:e13693	2010	21060874		Noah Saederup, Astrid E Cardona, Kelsey Croft, Makiko Mizutani, Anne C Cotleur, Chia-Lin Tsou, Richard M Ransohoff, Israel F Charo	Noah Saederup	Israel F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America.	NINDS NIH HHS; R01NS32151
Lu H, Huang D, Saederup N, Charo IF, Ransohoff RM, Zhou L	Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury.	FASEB J.	25:1:358-69	2011	20889618		Haiyan Lu, Danping Huang, Noah Saederup, Israel F Charo, Richard M Ransohoff, Lan Zhou	Haiyan Lu	Lan Zhou	Neuroinflammation Research Center, Department of Neurosciences, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave./S90, Cleveland, OH 44195, USA.	PHS HHS; MDA#91682
Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF	Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility.	J. Biol. Chem.	285:41:31418-26	2010	20675388		Wei Yan, Yue Si, Sarah Slaymaker, Jiachen Li, Huili Zheng, David L Young, Ara Aslanian, Laura Saunders, Eric Verdin, Israel F Charo	Wei Yan	Israel F Charo	Department of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, Nevada 89557, USA.	NICHD NIH HHS; R03 HD048855-02
Dai E, Liu LY, Wang H, McIvor D, Sun YM, Macaulay C, King E, Munuswamy-Ramanujam G, Bartee MY, Williams J, Davids J, Charo I, McFadden G, Esko JD, Lucas AR	Inhibition of chemokine-glycosaminoglycan interactions in donor tissue reduces mouse allograft vasculopathy and transplant rejection.	PLoS ONE	5:5:e10510	2010	20463901		Erbin Dai, Li-Ying Liu, Hao Wang, Dana McIvor, Yun Ming Sun, Colin Macaulay, Elaine King, Ganesh Munuswamy-Ramanujam, Mee Yong Bartee, Jennifer Williams, Jennifer Davids, Israel Charo, Grant McFadden, Jeffrey D Esko, Alexandra R Lucas	Erbin Dai	Alexandra R Lucas	Vascular Biology Research Group, Robarts Research Institute, The University of Western Ontario, London, Ontario, Canada.	Canadian Institutes of Health Research; MOP 577578
Si Y, Tsou CL, Croft K, Charo IF	CCR2 mediates hematopoietic stem and progenitor cell trafficking to sites of inflammation in mice.	J. Clin. Invest.	120:4:1192-203	2010	20234092		Yue Si, Chia-Lin Tsou, Kelsey Croft, Israel F Charo	Yue Si	Israel F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL052773
Daugherty A, Rateri DL, Charo IF, Owens AP, Howatt DA, Cassis LA	Angiotensin II infusion promotes ascending aortic aneurysms: attenuation by CCR2 deficiency in apoE-/- mice.	Clin. Sci.	118:11:681-9	2010	20088827		Alan Daugherty, Debra L Rateri, Israel F Charo, A Phillip Owens, Deborah A Howatt, Lisa A Cassis	Alan Daugherty	Lisa A Cassis	Saha Cardiovascular Research Center, University of Kentucky, Lexington, KY 40536, U.S.A. Alan.Daugherty@uky.edu	NHLBI NIH HHS; HL80100
Auffray C, Fogg DK, Narni-Mancinelli E, Senechal B, Trouillet C, Saederup N, Leemput J, Bigot K, Campisi L, Abitbol M, Molina T, Charo I, Hume DA, Cumano A, Lauvau G, Geissmann F	CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation.	J. Exp. Med.	206:3:595-606	2009	19273628		Cedric Auffray, Darin K Fogg, Emilie Narni-Mancinelli, Brigitte Senechal, Celine Trouillet, Noah Saederup, Julia Leemput, Karine Bigot, Laura Campisi, Marc Abitbol, Thierry Molina, Israel Charo, David A Hume, Ana Cumano, Gregoire Lauvau, Frederic Geissmann	Cedric Auffray	Frederic Geissmann	Laboratory of Biology of the Mononuclear Phagocyte System, Institut National de la Santé et de la Recherche Médicale U838, Université Paris-Descartes, 75015 Paris, France.	NA
Martin AP, Rankin S, Pitchford S, Charo IF, Furtado GC, Lira SA	Increased expression of CCL2 in insulin-producing cells of transgenic mice promotes mobilization of myeloid cells from the bone marrow, marked insulitis, and diabetes.	Diabetes	57:11:3025-33	2008	18633103		Andrea P Martin, Sara Rankin, Simon Pitchford, Israel F Charo, Glaucia C Furtado, Sergio A Lira	Andrea P Martin	Sergio A Lira	Immunology Institute, Mount Sinai School of Medicine, New York, New York, USA.	British Heart Foundation; PG/05/-92
Jia T, Serbina NV, Brandl K, Zhong MX, Leiner IM, Charo IF, Pamer EG	Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection.	J. Immunol.	180:10:6846-53	2008	18453605		Ting Jia, Natalya V Serbina, Katharina Brandl, Maggie X Zhong, Ingrid M Leiner, Israel F Charo, Eric G Pamer	Ting Jia	Eric G Pamer	Infectious Diseases Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.	NIAID NIH HHS; R37 AI039031-13
Alexis JD, Pyo RT, Chereshnev I, Katz J, Rollins BJ, Charo IF, Taubman MB	Inhibition of MCP-1/CCR2 signaling does not inhibit intimal proliferation in a mouse aortic transplant model.	J. Vasc. Res.	45:6:538-46	2008	18463419		Jeffrey D Alexis, Robert T Pyo, Igor Chereshnev, Jonathan Katz, Barrett J Rollins, Israel F Charo, Mark B Taubman	Jeffrey D Alexis	Mark B Taubman	Aab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14586, USA. jeffrey_alexis@urmc.rochester.edu	NA
Saederup N, Chan L, Lira SA, Charo IF	Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis.	Circulation	117:13:1642-8	2008	18165355		Noah Saederup, Liana Chan, Sergio A Lira, Israel F Charo	Noah Saederup	Israel F Charo	Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL63894
Charo IF	Macrophage polarization and insulin resistance: PPARgamma in control.	Cell Metab.	6:2:96-8	2007	17681144		Israel F Charo	Israel F Charo	Israel F Charo	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, and Department of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA. icharo@gladstone.ucsf.edu	NA
Tsou CL, Peters W, Si Y, Slaymaker S, Aslanian AM, Weisberg SP, Mack M, Charo IF	Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites.	J. Clin. Invest.	117:4:902-9	2007	17364026		Chia-Lin Tsou, Wendy Peters, Yue Si, Sarah Slaymaker, Ara M Aslanian, Stuart P Weisberg, Matthias Mack, Israel F Charo	Chia-Lin Tsou	Israel F Charo	Gladstone Institute of Cardiovascular Disease, UCSF, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL63894-07
Bennett JL, Elhofy A, Charo I, Miller SD, Dal Canto MC, Karpus WJ	CCR2 regulates development of Theiler's murine encephalomyelitis virus-induced demyelinating disease.	Viral Immunol.	20:1:19-33	2007	17425418		Jami L Bennett, Adam Elhofy, Israel Charo, Stephen D Miller, Mauro C Dal Canto, William J Karpus	Jami L Bennett	William J Karpus	Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.	NINDS NIH HHS; P01 NS023349
Wareing MD, Lyon A, Inglis C, Giannoni F, Charo I, Sarawar SR	Chemokine regulation of the inflammatory response to a low-dose influenza infection in CCR2-/- mice.	J. Leukoc. Biol.	81:3:793-801	2007	17179466		Mark D Wareing, Ashley Lyon, Chandra Inglis, Francesca Giannoni, Israel Charo, Sally R Sarawar	Mark D Wareing	Sally R Sarawar	Torrey Pines Institute for Molecular Studies, San diego, CA, USA. mark.wareing@ki.se	NIAID NIH HHS; AI44247
Sautter NB, Shick EH, Ransohoff RM, Charo IF, Hirose K	CC chemokine receptor 2 is protective against noise-induced hair cell death: studies in CX3CR1(+/GFP) mice.	J. Assoc. Res. Otolaryngol.	7:4:361-72	2006	17075702		Nathan B Sautter, Elizabeth H Shick, Richard M Ransohoff, Israel F Charo, Keiko Hirose	Nathan B Sautter	Keiko Hirose	Head and Neck Institute, Cleveland Clinic, Cleveland, OH 44195, USA.	NIDCD NIH HHS; K08 DC005761
Ragozzino D, Di Angelantonio S, Trettel F, Bertollini C, Maggi L, Gross C, Charo IF, Limatola C, Eusebi F	Chemokine fractalkine/CX3CL1 negatively modulates active glutamatergic synapses in rat hippocampal neurons.	J. Neurosci.	26:41:10488-98	2006	17035533		Davide Ragozzino, Silvia Di Angelantonio, Flavia Trettel, Cristina Bertollini, Laura Maggi, Cornelius Gross, Israel F Charo, Cristina Limatola, Fabrizio Eusebi	Davide Ragozzino	Fabrizio Eusebi	Istituto Pasteur-Fondazione Cenci Bolognetti and Dipartimento di Fisiologia Umana e Farmacologia, Università La Sapienza, Centro di Eccellenza BEMM, 00185 Roma, Italy. davide.ragozzino@uniroma1.it	NA
Aslanian AM, Charo IF	Targeted disruption of the scavenger receptor and chemokine CXCL16 accelerates atherosclerosis.	Circulation	114:6:583-90	2006	16880330		Ara M Aslanian, Israel F Charo	Ara M Aslanian	Israel F Charo	Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, Calif 94158, USA.	NHLBI NIH HHS; R01 HL63894-05
Green SR, Han KH, Chen Y, Almazan F, Charo IF, Miller YI, Quehenberger O	The CC chemokine MCP-1 stimulates surface expression of CX3CR1 and enhances the adhesion of monocytes to fractalkine/CX3CL1 via p38 MAPK.	J. Immunol.	176:12:7412-20	2006	16751386		Simone R Green, Ki Hoon Han, Yiming Chen, Felicidad Almazan, Israel F Charo, Yury I Miller, Oswald Quehenberger	Simone R Green	Oswald Quehenberger	Department of Medicine, University of California, San Diego, La Jolla, 92093, USA.	NHLBI NIH HHS; HL56989
Ali T, Humphries J, Burnand K, Sawyer B, Bursill C, Channon K, Greaves D, Rollins B, Charo IF, Smith A	Monocyte recruitment in venous thrombus resolution.	J. Vasc. Surg.	43:3:601-8	2006	16520180		Tahir Ali, Julia Humphries, Kevin Burnand, Barbara Sawyer, Christina Bursill, Keith Channon, David Greaves, Barrett Rollins, Israel F Charo, Alberto Smith	Tahir Ali	Alberto Smith	Academic Department of Surgery, Cardiovascular Division, GKT, King's College, St Thomas's Hospital, London, United Kingdom.	NHLBI NIH HHS; HL52773
Charo IF, Ransohoff RM	The many roles of chemokines and chemokine receptors in inflammation.	N. Engl. J. Med.	354:6:610-21	2006	16467548		Israel F Charo, Richard M Ransohoff	Israel F Charo	Richard M Ransohoff	Gladstone Institute of Cardiovascular Disease and the Cardiovascular Research Institute, Department of Medicine, University of California, San Francisco, San Francisco, USA. icharo@gladstone.ucsf.edu	NA
Oshima T, Sonoda KH, Tsutsumi-Miyahara C, Qiao H, Hisatomi T, Nakao S, Hamano S, Egashira K, Charo IF, Ishibashi T	Analysis of corneal inflammation induced by cauterisation in CCR2 and MCP-1 knockout mice.	Br J Ophthalmol	90:2:218-22	2006	16424537		T Oshima, K-H Sonoda, C Tsutsumi-Miyahara, H Qiao, T Hisatomi, S Nakao, S Hamano, K Egashira, I F Charo, T Ishibashi	T Oshima	T Ishibashi	Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka, Japan.	NA
Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, Charo I, Leibel RL, Ferrante AW	CCR2 modulates inflammatory and metabolic effects of high-fat feeding.	J. Clin. Invest.	116:1:115-24	2006	16341265		Stuart P Weisberg, Deborah Hunter, Reid Huber, Jacob Lemieux, Sarah Slaymaker, Kris Vaddi, Israel Charo, Rudolph L Leibel, Anthony W Ferrante	Stuart P Weisberg	Anthony W Ferrante	Department of Medicine, Naomi Berrie Diabetes Center, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.	NIDDK NIH HHS; R01 DK066525-02
Veillard NR, Steffens S, Pelli G, Lu B, Kwak BR, Gerard C, Charo IF, Mach F	Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo.	Circulation	112:6:870-8	2005	16061736		Niels R Veillard, Sabine Steffens, Graziano Pelli, B Lu, Brenda R Kwak, Craig Gerard, Israel F Charo, François Mach	Niels R Veillard	François Mach	Division of Cardiology, Foundation for Medical Research, University Hospital Geneva, Geneva, Switzerland.	NHLBI NIH HHS; HL63894
Huang D, Wujek J, Kidd G, He TT, Cardona A, Sasse ME, Stein EJ, Kish J, Tani M, Charo IF, Proudfoot AE, Rollins BJ, Handel T, Ransohoff RM	Chronic expression of monocyte chemoattractant protein-1 in the central nervous system causes delayed encephalopathy and impaired microglial function in mice.	FASEB J.	19:7:761-72	2005	15857890		Deren Huang, Jerome Wujek, Graham Kidd, Toby T He, Astrid Cardona, Margaret E Sasse, Erica J Stein, Jacqueline Kish, Marie Tani, Israel F Charo, Amanda E Proudfoot, Barrett J Rollins, Tracy Handel, Richard M Ransohoff	Deren Huang	Richard M Ransohoff	Department of Neurosciences, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.	NINDS NIH HHS; 3R01 NS32151-09
Aslanian AM, Chapman HA, Charo IF	Transient role for CD1d-restricted natural killer T cells in the formation of atherosclerotic lesions.	Arterioscler. Thromb. Vasc. Biol.	25:3:628-32	2005	15591216		Ara M Aslanian, Harold A Chapman, Israel F Charo	Ara M Aslanian	Israel F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, USA.	NHLBI NIH HHS; HL63894
Qu C, Edwards EW, Tacke F, Angeli V, Llodrá J, Sanchez-Schmitz G, Garin A, Haque NS, Peters W, van Rooijen N, Sanchez-Torres C, Bromberg J, Charo IF, Jung S, Lira SA, Randolph GJ	Role of CCR8 and other chemokine pathways in the migration of monocyte-derived dendritic cells to lymph nodes.	J. Exp. Med.	200:10:1231-41	2004	15534368		Chunfeng Qu, Emmerson W Edwards, Frank Tacke, Véronique Angeli, Jaime Llodrá, Guzman Sanchez-Schmitz, Alexandre Garin, Nasreen S Haque, Wendy Peters, Nico van Rooijen, Carmen Sanchez-Torres, Jonathan Bromberg, Israel F Charo, Steffen Jung, Sergio A Lira, Gwendalyn J Randolph	Chunfeng Qu	Gwendalyn J Randolph	Dept. of Gene and Cell Medicine, Mt. Sinai School of Medicine, Box 1496, 1425 Madison Ave., New York, NY 10029, USA.	NA
Charo IF, Taubman MB	Chemokines in the pathogenesis of vascular disease.	Circ. Res.	95:9:858-66	2004	15514167		Israel F Charo, Mark B Taubman	Israel F Charo	Mark B Taubman	Gladstone Institute of Cardiovascular Disease, PO Box 419100, San Francisco, CA 94141-9100, USA. icharo@gladstone.ucsf.edu	NHLBI NIH HHS; HL63984
Tang G, Charo DN, Wang R, Charo IF, Messina L	CCR2-/- knockout mice revascularize normally in response to severe hindlimb ischemia.	J. Vasc. Surg.	40:4:786-95	2004	15472609		Gale Tang, David N Charo, Rong Wang, Israel F Charo, Louis Messina	Gale Tang	Louis Messina	Pacific Vascular Research Laboratory, Department of Surgery, Division of Vascular Surgery, University of California, San Francisco 94143-0222, USA.	NHLBI NIH HHS; HL75353
Chiu BC, Freeman CM, Stolberg VR, Hu JS, Zeibecoglou K, Lu B, Gerard C, Charo IF, Lira SA, Chensue SW	Impaired lung dendritic cell activation in CCR2 knockout mice.	Am. J. Pathol.	165:4:1199-209	2004	15466386		Bo-Chin Chiu, Christine M Freeman, Valerie R Stolberg, Jerry S Hu, Kyriaki Zeibecoglou, Bao Lu, Craig Gerard, Israel F Charo, Sergio A Lira, Stephen W Chensue	Bo-Chin Chiu	Stephen W Chensue	Department of Pathology, University of Michigan Medical School, Ann Arbor, USA.	NIAID NIH HHS; R01 AI043460-06
Koth LL, Rodriguez MW, Bernstein XL, Chan S, Huang X, Charo IF, Rollins BJ, Erle DJ	Aspergillus antigen induces robust Th2 cytokine production, inflammation, airway hyperreactivity and fibrosis in the absence of MCP-1 or CCR2.	Respir. Res.	5:12	2004	15377395		Laura L Koth, Madeleine W Rodriguez, Xin Liu Bernstein, Salina Chan, Xiaozhu Huang, Israel F Charo, Barrett J Rollins, David J Erle	Laura L Koth	David J Erle	Lung Biology Center, Department of Medicine, University of California, San Francisco, California, USA. lkoth@itsa.ucsf.edu <lkoth@itsa.ucsf.edu>	NA
Tsutsumi-Miyahara C, Sonoda KH, Egashira K, Ishibashi M, Qiao H, Oshima T, Murata T, Miyazaki M, Charo IF, Hamano S, Ishibashi T	The relative contributions of each subset of ocular infiltrated cells in experimental choroidal neovascularisation.	Br J Ophthalmol	88:9:1217-22	2004	15317719		C Tsutsumi-Miyahara, K-H Sonoda, K Egashira, M Ishibashi, H Qiao, T Oshima, T Murata, M Miyazaki, I F Charo, S Hamano, T Ishibashi	C Tsutsumi-Miyahara	T Ishibashi	Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-Ku, Fukuoka 812-8582, Japan.	NA
Ishibashi M, Egashira K, Zhao Q, Hiasa K, Ohtani K, Ihara Y, Charo IF, Kura S, Tsuzuki T, Takeshita A, Sunagawa K	Bone marrow-derived monocyte chemoattractant protein-1 receptor CCR2 is critical in angiotensin II-induced acceleration of atherosclerosis and aneurysm formation in hypercholesterolemic mice.	Arterioscler. Thromb. Vasc. Biol.	24:11:e174-8	2004	15331433		Minako Ishibashi, Kensuke Egashira, Qingwei Zhao, Ken-ichi Hiasa, Kisho Ohtani, Yoshiko Ihara, Israel F Charo, Shinobu Kura, Teruhisa Tsuzuki, Akira Takeshita, Kenji Sunagawa	Minako Ishibashi	Kenji Sunagawa	Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.	NA
Peters W, Cyster JG, Mack M, Schlöndorff D, Wolf AJ, Ernst JD, Charo IF	CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosis.	J. Immunol.	172:12:7647-53	2004	15187146		Wendy Peters, Jason G Cyster, Matthias Mack, Detlef Schlöndorff, Andrea J Wolf, Joel D Ernst, Israel F Charo	Wendy Peters	Israel F Charo	Gladstone Institute of Cardiovascular Disease, PO Box 419100, San Francisco, CA 94141, USA. wpeters@gladstone.ucsf.edu	NIAID NIH HHS; AI 51242
Merad M, Hoffmann P, Ranheim E, Slaymaker S, Manz MG, Lira SA, Charo I, Cook DN, Weissman IL, Strober S, Engleman EG	Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease.	Nat. Med.	10:5:510-7	2004	15098028		Miriam Merad, Petra Hoffmann, Erik Ranheim, Sarah Slaymaker, Markus G Manz, Sergio A Lira, Israel Charo, Donald N Cook, Irving L Weissman, Samuel Strober, Edgar G Engleman	Miriam Merad	Edgar G Engleman	Department of Pathology, Stanford University School of Medicine, Palo Alto, California 94304, USA. miriam.merad@mssm.edu	NHLBI NIH HHS; HL57443
Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Charo IF, Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K	Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling.	Circ. Res.	94:9:1203-10	2004	15059935		Minako Ishibashi, Ken-ichi Hiasa, Qingwei Zhao, Shujiro Inoue, Kisho Ohtani, Shiro Kitamoto, Miyuki Tsuchihashi, Takeshi Sugaya, Israel F Charo, Shinobu Kura, Teruhisa Tsuzuki, Tatsuro Ishibashi, Akira Takeshita, Kensuke Egashira	Minako Ishibashi	Kensuke Egashira	Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyushu University, Fukuoka, Japan.	NA
Schecter AD, Berman AB, Yi L, Ma H, Daly CM, Soejima K, Rollins BJ, Charo IF, Taubman MB	MCP-1-dependent signaling in CCR2(-/-) aortic smooth muscle cells.	J. Leukoc. Biol.	75:6:1079-85	2004	15020650		Alison D Schecter, Adriane B Berman, Lin Yi, Harry Ma, Christine M Daly, Kenzo Soejima, Barrett J Rollins, Israel F Charo, Mark B Taubman	Alison D Schecter	Mark B Taubman	The Cardiovascular Institute, Department of Medicine, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA. alison.schecter@mssm.edu	NIGMS NIH HHS; T32GM07288
Abdi R, Means TK, Ito T, Smith RN, Najafian N, Jurewicz M, Tchipachvili V, Charo I, Auchincloss H, Sayegh MH, Luster AD	Differential role of CCR2 in islet and heart allograft rejection: tissue specificity of chemokine/chemokine receptor function in vivo.	J. Immunol.	172:2:767-75	2004	14707046		Reza Abdi, Terry K Means, Toshiro Ito, Rex Neal Smith, Nader Najafian, Mollie Jurewicz, Vaja Tchipachvili, Israel Charo, Hugh Auchincloss, Mohamed H Sayegh, Andrew D Luster	Reza Abdi	Andrew D Luster	Laboratory of Immunogenetics and Transplantation, Renal Division, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02120, USA. rabdi@rics.bwh.harvard.edu	NCI NIH HHS; R01 CA 69212
Gharaee-Kermani M, McCullumsmith RE, Charo IF, Kunkel SL, Phan SH	CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis.	Cytokine	24:6:266-76	2003	14609568		Mehrnaz Gharaee-Kermani, Robert E McCullumsmith, Israel F Charo, Steven L Kunkel, Sem H Phan	Mehrnaz Gharaee-Kermani	Sem H Phan	Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109-0602, USA.	NHLBI NIH HHS; HL52285
Panoskaltsis-Mortari A, Hermanson JR, Taras E, Wangensteen OD, Charo IF, Rollins BJ, Blazar BR	Post-BMT lung injury occurs independently of the expression of CCL2 or its receptor, CCR2, on host cells.	Am. J. Physiol. Lung Cell Mol. Physiol.	286:2:L284-92	2004	14527928		Angela Panoskaltsis-Mortari, John R Hermanson, Elizabeth Taras, O Douglas Wangensteen, Israel F Charo, Barrett J Rollins, Bruce R Blazar	Angela Panoskaltsis-Mortari	Bruce R Blazar	University of Minnesota, Department of Pediatrics, Division of Hematology-Oncology, 420 Delaware St. SE, Minneapolis, MN 55455, USA. panos001@umn.edu	NHLBI NIH HHS; R01-HL-66308
Tsutsumi C, Sonoda KH, Egashira K, Qiao H, Hisatomi T, Nakao S, Ishibashi M, Charo IF, Sakamoto T, Murata T, Ishibashi T	The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization.	J. Leukoc. Biol.	74:1:25-32	2003	12832439		Chikako Tsutsumi, Koh-Hei Sonoda, Kensuke Egashira, Hong Qiao, Toshio Hisatomi, Shintaro Nakao, Minako Ishibashi, Israel F Charo, Taiji Sakamoto, Toshinori Murata, Tatsuro Ishibashi	Chikako Tsutsumi	Tatsuro Ishibashi	Department of Ophthalmology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.	NA
Charo IF, Peters W	Chemokine receptor 2 (CCR2) in atherosclerosis, infectious diseases, and regulation of T-cell polarization.	Microcirculation	10:3-4:259-64	2003	12851643		Israel F Charo, Wendy Peters	Israel F Charo	Wendy Peters	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA. icharo@gladstone.ucsf.edu	NHLBI NIH HHS; HL52773
Lesnik P, Haskell CA, Charo IF	Decreased atherosclerosis in CX3CR1-/- mice reveals a role for fractalkine in atherogenesis.	J. Clin. Invest.	111:3:333-40	2003	12569158		Philippe Lesnik, Christopher A Haskell, Israel F Charo	Philippe Lesnik	Israel F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL-63894
Stein O, Dabach Y, Ben-Naim M, Halperin G, Charo IF, Stein Y	In CCR2-/- mice monocyte recruitment and egress of LDL cholesterol in vivo is impaired.	Biochem. Biophys. Res. Commun.	300:2:477-81	2003	12504109		Olga Stein, Yedida Dabach, Mazal Ben-Naim, Gideon Halperin, Israel F Charo, Yechezkiel Stein	Olga Stein	Yechezkiel Stein	Department of Experimental Medicine and Cancer Research, Hebrew University-Hadassah Medical School, Jerusalem, Israel.	NA
Huang D, Tani M, Wang J, Han Y, He TT, Weaver J, Charo IF, Tuohy VK, Rollins BJ, Ransohoff RM	Pertussis toxin-induced reversible encephalopathy dependent on monocyte chemoattractant protein-1 overexpression in mice.	J. Neurosci.	22:24:10633-42	2002	12486156		DeRen Huang, Marie Tani, Jintang Wang, Yulong Han, Toby T He, Jennifer Weaver, Israel F Charo, Vincent K Tuohy, Barrett J Rollins, Richard M Ransohoff	DeRen Huang	Richard M Ransohoff	Department of Neurosciences, Lerner Research Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.	NINDS NIH HHS; 2R01 NS32151-09
Merad M, Manz MG, Karsunky H, Wagers A, Peters W, Charo I, Weissman IL, Cyster JG, Engleman EG	Langerhans cells renew in the skin throughout life under steady-state conditions.	Nat. Immunol.	3:12:1135-41	2002	12415265		Miriam Merad, Markus G Manz, Holger Karsunky, Amy Wagers, Wendy Peters, Israel Charo, Irving L Weissman, Jason G Cyster, Edgar G Engleman	Miriam Merad	Edgar G Engleman	Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA. meradm@stanford.edu	NHLBI NIH HHS; HL57443
Ma M, Wei T, Boring L, Charo IF, Ransohoff RM, Jakeman LB	Monocyte recruitment and myelin removal are delayed following spinal cord injury in mice with CCR2 chemokine receptor deletion.	J. Neurosci. Res.	68:6:691-702	2002	12111830		Manhong Ma, Tao Wei, Landin Boring, Israel F Charo, Richard M Ransohoff, Lyn B Jakeman	Manhong Ma	Lyn B Jakeman	Department of Physiology and Cell Biology, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio, USA.	NINDS NIH HHS; NS32151
Egashira K, Zhao Q, Kataoka C, Ohtani K, Usui M, Charo IF, Nishida K, Inoue S, Katoh M, Ichiki T, Takeshita A	Importance of monocyte chemoattractant protein-1 pathway in neointimal hyperplasia after periarterial injury in mice and monkeys.	Circ. Res.	90:11:1167-72	2002	12065319		Kensuke Egashira, Qingwei Zhao, Chu Kataoka, Kishou Ohtani, Makoto Usui, Israel F Charo, Ken-Ichi Nishida, Shujiro Inoue, Makoto Katoh, Toshihiro Ichiki, Akira Takeshita	Kensuke Egashira	Akira Takeshita	Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan. egashira@cardiol.med.kyushu-u.ac.jp	NA
Tylaska LA, Boring L, Weng W, Aiello R, Charo IF, Rollins BJ, Gladue RP	Ccr2 regulates the level of MCP-1/CCL2 in vitro and at inflammatory sites and controls T cell activation in response to alloantigen.	Cytokine	18:4:184-90	2002	12126640		L A Tylaska, L Boring, W Weng, R Aiello, I F Charo, B J Rollins, R P Gladue	L A Tylaska	R P Gladue	Pfizer Global Research and Development, Department of Immunology, Groton, CT 06340, USA. Ronald_P_Gladue@Groton.Pfizer.com	NA
Roque M, Kim WJ, Gazdoin M, Malik A, Reis ED, Fallon JT, Badimon JJ, Charo IF, Taubman MB	CCR2 deficiency decreases intimal hyperplasia after arterial injury.	Arterioscler. Thromb. Vasc. Biol.	22:4:554-9	2002	11950690		Merce Roque, William J H Kim, Michaela Gazdoin, Alia Malik, Ernane D Reis, John T Fallon, Juan J Badimon, Israel F Charo, Mark B Taubman	Merce Roque	Mark B Taubman	Zena and Michael A. Wiener Cardiovascular Institute, Department of Medicine, Mount Sinai School of Medicine, New York, NY, USA.	NHLBI NIH HHS; T32 HL07824
Keppler OT, Welte FJ, Ngo TA, Chin PS, Patton KS, Tsou CL, Abbey NW, Sharkey ME, Grant RM, You Y, Scarborough JD, Ellmeier W, Littman DR, Stevenson M, Charo IF, Herndier BG, Speck RF, Goldsmith MA	Progress toward a human CD4/CCR5 transgenic rat model for de novo infection by human immunodeficiency virus type 1.	J. Exp. Med.	195:6:719-36	2002	11901198		Oliver T Keppler, Frank J Welte, Tuan A Ngo, Peggy S Chin, Kathryn S Patton, Chia-Lin Tsou, Nancy W Abbey, Mark E Sharkey, Robert M Grant, Yun You, John D Scarborough, Wilfried Ellmeier, Dan R Littman, Mario Stevenson, Israel F Charo, Brian G Herndier, Roberto F Speck, Mark A Goldsmith	Oliver T Keppler	Mark A Goldsmith	Gladstone Institute of Virology and Immunology, School of Medicine, University of California at San Francisco, San Francisco, CA 94141, USA.	NIAID NIH HHS; R21-AI 46258
Zhu Z, Ma B, Zheng T, Homer RJ, Lee CG, Charo IF, Noble P, Elias JA	IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling.	J. Immunol.	168:6:2953-62	2002	11884467		Zhou Zhu, Bing Ma, Tao Zheng, Robert J Homer, Chun Geun Lee, Israel F Charo, Paul Noble, Jack A Elias	Zhou Zhu	Jack A Elias	Section of Pulmonary and Critical Care Medicine, Departments of Internal Medicine and Pathology, Yale University School of Medicine, New Haven, CT 06520, USA.	NHLBI NIH HHS; HL-64242
Dupuis M, Denis-Mize K, LaBarbara A, Peters W, Charo IF, McDonald DM, Ott G	Immunization with the adjuvant MF59 induces macrophage trafficking and apoptosis.	Eur. J. Immunol.	31:10:2910-8	2001	11592066		M Dupuis, K Denis-Mize, A LaBarbara, W Peters, I F Charo, D M McDonald, G Ott	M Dupuis	G Ott	Cardiovascular Research Institute and Department of Anatomy, University of California, San Francisco, USA.	NHLBI NIH HHS; HL 24136
Tsou CL, Haskell CA, Charo IF	Tumor necrosis factor-alpha-converting enzyme mediates the inducible cleavage of fractalkine.	J. Biol. Chem.	276:48:44622-6	2001	11571300		C L Tsou, C A Haskell, I F Charo	C L Tsou	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL 63894
Haskell CA, Hancock WW, Salant DJ, Gao W, Csizmadia V, Peters W, Faia K, Fituri O, Rottman JB, Charo IF	Targeted deletion of CX(3)CR1 reveals a role for fractalkine in cardiac allograft rejection.	J. Clin. Invest.	108:5:679-88	2001	11544273		C A Haskell, W W Hancock, D J Salant, W Gao, V Csizmadia, W Peters, K Faia, O Fituri, J B Rottman, I F Charo	C A Haskell	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL-63894
Belperio JA, Keane MP, Burdick MD, Lynch JP, Xue YY, Berlin A, Ross DJ, Kunkel SL, Charo IF, Strieter RM	Critical role for the chemokine MCP-1/CCR2 in the pathogenesis of bronchiolitis obliterans syndrome.	J. Clin. Invest.	108:4:547-56	2001	11518728		J A Belperio, M P Keane, M D Burdick, J P Lynch, Y Y Xue, A Berlin, D J Ross, S L Kunkel, I F Charo, R M Strieter	J A Belperio	R M Strieter	Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California Los Angeles School of Medicine, Los Angeles, California 90024-1922, USA.	NHLBI NIH HHS; P50HL-67665
Peters W, Scott HM, Chambers HF, Flynn JL, Charo IF, Ernst JD	Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis.	Proc. Natl. Acad. Sci. U.S.A.	98:14:7958-63	2001	11438742		W Peters, H M Scott, H F Chambers, J L Flynn, I F Charo, J D Ernst	W Peters	J D Ernst	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL52773
Drake PM, Gunn MD, Charo IF, Tsou CL, Zhou Y, Huang L, Fisher SJ	Human placental cytotrophoblasts attract monocytes and CD56(bright) natural killer cells via the actions of monocyte inflammatory protein 1alpha.	J. Exp. Med.	193:10:1199-212	2001	11369791		P M Drake, M D Gunn, I F Charo, C L Tsou, Y Zhou, L Huang, S J Fisher	P M Drake	S J Fisher	Department of Biochemistry and Biophysics, University of California at San Francisco, CA 94143, USA.	NHLBI NIH HHS; HL64597
Peters W, Charo IF	Involvement of chemokine receptor 2 and its ligand, monocyte chemoattractant protein-1, in the development of atherosclerosis: lessons from knockout mice.	Curr. Opin. Lipidol.	12:2:175-80	2001	11264989		W Peters, I F Charo	W Peters	I F Charo	Gladstone Institute of Cardiovascular Disease, and Cardiovascular Research Institute, Department of Medicine, University of California, San Francisco, California 94141-9100, USA.	NA
Peters W, Dupuis M, Charo IF	A mechanism for the impaired IFN-gamma production in C-C chemokine receptor 2 (CCR2) knockout mice: role of CCR2 in linking the innate and adaptive immune responses.	J. Immunol.	165:12:7072-7	2000	11120836		W Peters, M Dupuis, I F Charo	W Peters	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141, USA.	NHLBI NIH HHS; HL52773
MacLean JA, De Sanctis GT, Ackerman KG, Drazen JM, Sauty A, DeHaan E, Green FH, Charo IF, Luster AD	CC chemokine receptor-2 is not essential for the development of antigen-induced pulmonary eosinophilia and airway hyperresponsiveness.	J. Immunol.	165:11:6568-75	2000	11086100		J A MacLean, G T De Sanctis, K G Ackerman, J M Drazen, A Sauty, E DeHaan, F H Green, I F Charo, A D Luster	J A MacLean	A D Luster	Center for Immunology and Inflammatory Disease, Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Pulmonary and Critical Care Divisions, Brigham and Women's Hospital, Boston, MA 02114, USA.	NCI NIH HHS; CA69212
Haskell CA, Cleary MD, Charo IF	Unique role of the chemokine domain of fractalkine in cell capture. Kinetics of receptor dissociation correlate with cell adhesion.	J. Biol. Chem.	275:44:34183-9	2000	10940307		C A Haskell, M D Cleary, I F Charo	C A Haskell	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL-63894
Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD	Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.	J. Exp. Med.	192:7:1075-80	2000	11015448		L Izikson, R S Klein, I F Charo, H L Weiner, A D Luster	L Izikson	A D Luster	Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.	NCI NIH HHS; R01CA69212
Blease K, Mehrad B, Standiford TJ, Lukacs NW, Gosling J, Boring L, Charo IF, Kunkel SL, Hogaboam CM	Enhanced pulmonary allergic responses to Aspergillus in CCR2-/- mice.	J. Immunol.	165:5:2603-11	2000	10946288		K Blease, B Mehrad, T J Standiford, N W Lukacs, J Gosling, L Boring, I F Charo, S L Kunkel, C M Hogaboam	K Blease	C M Hogaboam	Department of Pathology, Division of Pulmonary and Critical Care, University of Michigan Medical School, Ann Arbor, MI 48109, USA.	NHLBI NIH HHS; K08 HL04220-01
Hogaboam CM, Bone-Larson CL, Steinhauser ML, Matsukawa A, Gosling J, Boring L, Charo IF, Simpson KJ, Lukacs NW, Kunkel SL	Exaggerated hepatic injury due to acetaminophen challenge in mice lacking C-C chemokine receptor 2.	Am. J. Pathol.	156:4:1245-52	2000	10751350		C M Hogaboam, C L Bone-Larson, M L Steinhauser, A Matsukawa, J Gosling, L Boring, I F Charo, K J Simpson, N W Lukacs, S L Kunkel	C M Hogaboam	S L Kunkel	Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109-0602, USA. hogaboam@path.med.umich.edu	NCI NIH HHS; CA66180
Murphy PM, Baggiolini M, Charo IF, Hébert CA, Horuk R, Matsushima K, Miller LH, Oppenheim JJ, Power CA	International union of pharmacology. XXII. Nomenclature for chemokine receptors.	Pharmacol. Rev.	52:1:145-76	2000	10699158		P M Murphy, M Baggiolini, I F Charo, C A Hébert, R Horuk, K Matsushima, L H Miller, J J Oppenheim, C A Power	P M Murphy	C A Power	Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. pmm@nih.gov	NA
Campbell EM, Charo IF, Kunkel SL, Strieter RM, Boring L, Gosling J, Lukacs NW	Monocyte chemoattractant protein-1 mediates cockroach allergen-induced bronchial hyperreactivity in normal but not CCR2-/- mice: the role of mast cells.	J. Immunol.	163:4:2160-7	1999	10438957		E M Campbell, I F Charo, S L Kunkel, R M Strieter, L Boring, J Gosling, N W Lukacs	E M Campbell	N W Lukacs	Department of Pathology, Division of Pulmonary and Critical Care, University of Michigan Medical School, Ann Arbor 48109, USA.	NHLBI NIH HHS; HL 52773
Haskell CA, Cleary MD, Charo IF	Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation.	J. Biol. Chem.	274:15:10053-8	1999	10187784		C A Haskell, M D Cleary, I F Charo	C A Haskell	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL52773
Gosling J, Slaymaker S, Gu L, Tseng S, Zlot CH, Young SG, Rollins BJ, Charo IF	MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.	J. Clin. Invest.	103:6:773-8	1999	10079097		J Gosling, S Slaymaker, L Gu, S Tseng, C H Zlot, S G Young, B J Rollins, I F Charo	J Gosling	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL-52773
Reid S, Ritchie A, Boring L, Gosling J, Cooper S, Hangoc G, Charo IF, Broxmeyer HE	Enhanced myeloid progenitor cell cycling and apoptosis in mice lacking the chemokine receptor, CCR2.	Blood	93:5:1524-33	1999	10029580		S Reid, A Ritchie, L Boring, J Gosling, S Cooper, G Hangoc, I F Charo, H E Broxmeyer	S Reid	H E Broxmeyer	Departments of Microbiology/Immunology and Medicine, and The Walther Oncology Center, Indiana University School of Medicine, Indianapolis, IN, USA.	NHLBI NIH HHS; R01 HL56416
Charo IF	CCR2: from cloning to the creation of knockout mice.	Chem. Immunol.	72:30-41	1999	10550928		I F Charo	I F Charo	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, Calif., USA. icharo@gladstone.ucsf.edu	NA
Boring L, Gosling J, Cleary M, Charo IF	Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis.	Nature	394:6696:894-7	1998	9732872		L Boring, J Gosling, M Cleary, I F Charo	L Boring	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141, USA.	NA
Tsou CL, Gladue RP, Carroll LA, Paradis T, Boyd JG, Nelson RT, Neote K, Charo IF	Identification of C-C chemokine receptor 1 (CCR1) as the monocyte hemofiltrate C-C chemokine (HCC)-1 receptor.	J. Exp. Med.	188:3:603-8	1998	9687537		C L Tsou, R P Gladue, L A Carroll, T Paradis, J G Boyd, R T Nelson, K Neote, I F Charo	C L Tsou	I F Charo	Gladstone Institute of Cardiovascular Disease, the Cardiovascular Research Institute, and the Department of Medicine, University of California, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL-52773
Arai H, Tsou CL, Charo IF	Chemotaxis in a lymphocyte cell line transfected with C-C chemokine receptor 2B: evidence that directed migration is mediated by betagamma dimers released by activation of Galphai-coupled receptors.	Proc. Natl. Acad. Sci. U.S.A.	94:26:14495-9	1997	9405641		H Arai, C L Tsou, I F Charo	H Arai	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL52773
Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RV, Broxmeyer HE, Charo IF	Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice.	J. Clin. Invest.	100:10:2552-61	1997	9366570		L Boring, J Gosling, S W Chensue, S L Kunkel, R V Farese, H E Broxmeyer, I F Charo	L Boring	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL-56416
Schecter AD, Rollins BJ, Zhang YJ, Charo IF, Fallon JT, Rossikhina M, Giesen PL, Nemerson Y, Taubman MB	Tissue factor is induced by monocyte chemoattractant protein-1 in human aortic smooth muscle and THP-1 cells.	J. Biol. Chem.	272:45:28568-73	1997	9353321		A D Schecter, B J Rollins, Y J Zhang, I F Charo, J T Fallon, M Rossikhina, P L Giesen, Y Nemerson, M B Taubman	A D Schecter	M B Taubman	Cardiovascular Institute, The Mount Sinai School of Medicine, New York, New York 10029, USA.	NHLBI NIH HHS; HL29019
Arai H, Monteclaro FS, Tsou CL, Franci C, Charo IF	Dissociation of chemotaxis from agonist-induced receptor internalization in a lymphocyte cell line transfected with CCR2B. Evidence that directed migration does not require rapid modulation of signaling at the receptor level.	J. Biol. Chem.	272:40:25037-42	1997	9312111		H Arai, F S Monteclaro, C L Tsou, C Franci, I F Charo	H Arai	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL52773
Monteclaro FS, Charo IF	The amino-terminal domain of CCR2 is both necessary and sufficient for high affinity binding of monocyte chemoattractant protein 1. Receptor activation by a pseudo-tethered ligand.	J. Biol. Chem.	272:37:23186-90	1997	9287323		F S Monteclaro, I F Charo	F S Monteclaro	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL52773
Speck RF, Wehrly K, Platt EJ, Atchison RE, Charo IF, Kabat D, Chesebro B, Goldsmith MA	Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop.	J. Virol.	71:9:7136-9	1997	9261451		R F Speck, K Wehrly, E J Platt, R E Atchison, I F Charo, D Kabat, B Chesebro, M A Goldsmith	R F Speck	M A Goldsmith	Gladstone Institute of Virology and Immunology, San Francisco, California, USA.	NCI NIH HHS; CA 67358
Gosling J, Monteclaro FS, Atchison RE, Arai H, Tsou CL, Goldsmith MA, Charo IF	Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity.	Proc. Natl. Acad. Sci. U.S.A.	94:10:5061-6	1997	9144190		J Gosling, F S Monteclaro, R E Atchison, H Arai, C L Tsou, M A Goldsmith, I F Charo	J Gosling	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94110, USA.	NHLBI NIH HHS; HL52773
Wong LM, Myers SJ, Tsou CL, Gosling J, Arai H, Charo IF	Organization and differential expression of the human monocyte chemoattractant protein 1 receptor gene. Evidence for the role of the carboxyl-terminal tail in receptor trafficking.	J. Biol. Chem.	272:2:1038-45	1997	8995400		L M Wong, S J Myers, C L Tsou, J Gosling, H Arai, I F Charo	L M Wong	I F Charo	Daiichi Research Center, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL52773
Sarafi MN, Garcia-Zepeda EA, MacLean JA, Charo IF, Luster AD	Murine monocyte chemoattractant protein (MCP)-5: a novel CC chemokine that is a structural and functional homologue of human MCP-1.	J. Exp. Med.	185:1:99-109	1997	8996246		M N Sarafi, E A Garcia-Zepeda, J A MacLean, I F Charo, A D Luster	M N Sarafi	A D Luster	Infectious Disease Unit, Massachusetts General Hospital, Boston, USA.	NHLBI NIH HHS; HL52773
Monteclaro FS, Arai H, Charo IF	Molecular approaches to identifying ligand binding and signaling domains of C-C chemokine receptors.	Meth. Enzymol.	288:70-84	1997	9356988		F S Monteclaro, H Arai, I F Charo	F S Monteclaro	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141, USA.	NA
Franci C, Gosling J, Tsou CL, Coughlin SR, Charo IF	Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function.	J. Immunol.	157:12:5606-12	1996	8955213		C Franci, J Gosling, C L Tsou, S R Coughlin, I F Charo	C Franci	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94143, USA.	NHLBI NIH HHS; HL52773
Atchison RE, Gosling J, Monteclaro FS, Franci C, Digilio L, Charo IF, Goldsmith MA	Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines.	Science	274:5294:1924-6	1996	8943208		R E Atchison, J Gosling, F S Monteclaro, C Franci, L Digilio, I F Charo, M A Goldsmith	R E Atchison	M A Goldsmith	Gladstone Institute of Virology and Immunology, School of Medicine, University of California, San Francisco, Post Office Box 419100, San Francisco, CA 94141-9100, USA. mark_goldsmith@quickmail.ucsf.edu	NHLBI NIH HHS; HL52773
Arai H, Charo IF	Differential regulation of G-protein-mediated signaling by chemokine receptors.	J. Biol. Chem.	271:36:21814-9	1996	8702980		H Arai, I F Charo	H Arai	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL52773
Monteclaro FS, Charo IF	The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation.	J. Biol. Chem.	271:32:19084-92	1996	8702581		F S Monteclaro, I F Charo	F S Monteclaro	I F Charo	Gladstone Institute of Cardiovascular Disease, University of California San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL52773
Raport CJ, Gosling J, Schweickart VL, Gray PW, Charo IF	Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1beta, and MIP-1alpha.	J. Biol. Chem.	271:29:17161-6	1996	8663314		C J Raport, J Gosling, V L Schweickart, P W Gray, I F Charo	C J Raport	I F Charo	ICOS Corporation, Bothell, Washington 98021, USA.	NHLBI NIH HHS; HL52773
Boring L, Gosling J, Monteclaro FS, Lusis AJ, Tsou CL, Charo IF	Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9.	J. Biol. Chem.	271:13:7551-8	1996	8631787		L Boring, J Gosling, F S Monteclaro, A J Lusis, C L Tsou, I F Charo	L Boring	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL52773
Franci C, Wong LM, Van Damme J, Proost P, Charo IF	Monocyte chemoattractant protein-3, but not monocyte chemoattractant protein-2, is a functional ligand of the human monocyte chemoattractant protein-1 receptor.	J. Immunol.	154:12:6511-7	1995	7759884		C Franci, L M Wong, J Van Damme, P Proost, I F Charo	C Franci	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94110, USA.	NHLBI NIH HHS; HL52773
Myers SJ, Wong LM, Charo IF	Signal transduction and ligand specificity of the human monocyte chemoattractant protein-1 receptor in transfected embryonic kidney cells.	J. Biol. Chem.	270:11:5786-92	1995	7890708		S J Myers, L M Wong, I F Charo	S J Myers	I F Charo	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100.	NHLBI NIH HHS; HL52773
Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR	Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails.	Proc. Natl. Acad. Sci. U.S.A.	91:7:2752-6	1994	8146186		I F Charo, S J Myers, A Herman, C Franci, A J Connolly, S R Coughlin	I F Charo	S R Coughlin	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100.	NHLBI NIH HHS; HL43322
Scarborough RM, Rose JW, Naughton MA, Phillips DR, Nannizzi L, Arfsten A, Campbell AM, Charo IF	Characterization of the integrin specificities of disintegrins isolated from American pit viper venoms.	J. Biol. Chem.	268:2:1058-65	1993	8419314		R M Scarborough, J W Rose, M A Naughton, D R Phillips, L Nannizzi, A Arfsten, A M Campbell, I F Charo	R M Scarborough	I F Charo	COR Therapeutics, Inc., South San Francisco, California 94080.	NA
Scarborough RM, Naughton MA, Teng W, Rose JW, Phillips DR, Nannizzi L, Arfsten A, Campbell AM, Charo IF	Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa.	J. Biol. Chem.	268:2:1066-73	1993	8419315		R M Scarborough, M A Naughton, W Teng, J W Rose, D R Phillips, L Nannizzi, A Arfsten, A M Campbell, I F Charo	R M Scarborough	I F Charo	COR Therapeutics, Inc., South San Francisco, California 94080.	NA
Nelken NA, Soifer SJ, O'Keefe J, Vu TK, Charo IF, Coughlin SR	Thrombin receptor expression in normal and atherosclerotic human arteries.	J. Clin. Invest.	90:4:1614-21	1992	1328304		N A Nelken, S J Soifer, J O'Keefe, T K Vu, I F Charo, S R Coughlin	N A Nelken	S R Coughlin	Cardiovascular Research Institute, University of California, San Francisco 94143.	NHLBI NIH HHS; HL-44907
Hung DT, Vu TK, Wheaton VI, Charo IF, Nelken NA, Esmon N, Esmon CT, Coughlin SR	"Mirror image" antagonists of thrombin-induced platelet activation based on thrombin receptor structure.	J. Clin. Invest.	89:2:444-50	1992	1310695		D T Hung, T K Vu, V I Wheaton, I F Charo, N A Nelken, N Esmon, C T Esmon, S R Coughlin	D T Hung	S R Coughlin	Department of Medicine, University of California, San Francisco 94143.	NHLBI NIH HHS; HL0248-01
Vu TK, Wheaton VI, Hung DT, Charo I, Coughlin SR	Domains specifying thrombin-receptor interaction.	Nature	353:6345:674-7	1991	1717851		T K Vu, V I Wheaton, D T Hung, I Charo, S R Coughlin	T K Vu	S R Coughlin	Cardiovascular Research Institute, University of California, San Francisco 94143-0524.	NA
Scarborough RM, Rose JW, Hsu MA, Phillips DR, Fried VA, Campbell AM, Nannizzi L, Charo IF	Barbourin. A GPIIb-IIIa-specific integrin antagonist from the venom of Sistrurus m. barbouri.	J. Biol. Chem.	266:15:9359-62	1991	2033037		R M Scarborough, J W Rose, M A Hsu, D R Phillips, V A Fried, A M Campbell, L Nannizzi, I F Charo	R M Scarborough	I F Charo	COR Therapeutics, Inc., South San Francisco, California 94080.	NA
Phillips DR, Charo IF, Scarborough RM	GPIIb-IIIa: the responsive integrin.	Cell	65:3:359-62	1991	2018971		D R Phillips, I F Charo, R M Scarborough	D R Phillips	R M Scarborough	COR Therapeutics, Inc., South San Francisco, California 94080.	NA
Charo IF, Nannizzi L, Phillips DR, Hsu MA, Scarborough RM	Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide.	J. Biol. Chem.	266:3:1415-21	1991	1703149		I F Charo, L Nannizzi, D R Phillips, M A Hsu, R M Scarborough	I F Charo	R M Scarborough	COR Therapeutics Inc., South San Francisco, California 94080.	NA
Charo IF, Nannizzi L, Smith JW, Cheresh DA	The vitronectin receptor alpha v beta 3 binds fibronectin and acts in concert with alpha 5 beta 1 in promoting cellular attachment and spreading on fibronectin.	J. Cell Biol.	111:6 Pt 1:2795-800	1990	1703545		I F Charo, L Nannizzi, J W Smith, D A Cheresh	I F Charo	D A Cheresh	COR Therapeutics, Inc., South San Francisco, California 94080.	NA
Brown DL, Phillips DR, Damsky CH, Charo IF	Synthesis and expression of the fibroblast fibronectin receptor in human monocytes.	J. Clin. Invest.	84:1:366-70	1989	2472429		D L Brown, D R Phillips, C H Damsky, I F Charo	D L Brown	I F Charo	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL-01751
Phillips DR, Charo IF, Parise LV, Fitzgerald LA	The platelet membrane glycoprotein IIb-IIIa complex.	Blood	71:4:831-43	1988	2833328		D R Phillips, I F Charo, L V Parise, L A Fitzgerald	D R Phillips	L A Fitzgerald	Gladstone Foundation Laboratories, University of California, San Francisco 94140.	NHLBI NIH HHS; HL32254
Charo IF, Bekeart LS, Phillips DR	Platelet glycoprotein IIb-IIIa-like proteins mediate endothelial cell attachment to adhesive proteins and the extracellular matrix.	J. Biol. Chem.	262:21:9935-8	1987	2440865		I F Charo, L S Bekeart, D R Phillips	I F Charo	D R Phillips		NHLBI NIH HHS; HL 28947
Phillips DR, Fitzgerald LA, Charo IF, Parise LV	The platelet membrane glycoprotein IIb/IIIa complex. Structure, function, and relationship to adhesive protein receptors in nucleated cells.	Ann. N. Y. Acad. Sci.	509:177-87	1987	2827553		D R Phillips, L A Fitzgerald, I F Charo, L V Parise	D R Phillips	L V Parise	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL 38405
Charo IF, Fitzgerald LA, Steiner B, Rall SC, Bekeart LS, Phillips DR	Platelet glycoproteins IIb and IIIa: evidence for a family of immunologically and structurally related glycoproteins in mammalian cells.	Proc. Natl. Acad. Sci. U.S.A.	83:21:8351-5	1986	3534886		I F Charo, L A Fitzgerald, B Steiner, S C Rall, L S Bekeart, D R Phillips	I F Charo	D R Phillips		NHLBI NIH HHS; HL32254
Charo IF, Yuen C, Perez HD, Goldstein IM	Chemotactic peptides modulate adherence of human polymorphonuclear leukocytes to monolayers of cultured endothelial cells.	J. Immunol.	136:9:3412-9	1986	3514759		I F Charo, C Yuen, H D Perez, I M Goldstein	I F Charo	I M Goldstein		NHLBI NIH HHS; HL-28475
Fitzgerald LA, Charo IF, Phillips DR	Human and bovine endothelial cells synthesize membrane proteins similar to human platelet glycoproteins IIb and IIIa.	J. Biol. Chem.	260:20:10893-6	1985	3161885		L A Fitzgerald, I F Charo, D R Phillips	L A Fitzgerald	D R Phillips		NHLBI NIH HHS; HL32254
Charo IF, Yuen C, Goldstein IM	Adherence of human polymorphonuclear leukocytes to endothelial monolayers: effects of temperature, divalent cations, and chemotactic factors on the strength of adherence measured with a new centrifugation assay.	Blood	65:2:473-9	1985	3967088		I F Charo, C Yuen, I M Goldstein	I F Charo	I M Goldstein		NHLBI NIH HHS; HL-28475
Charo IF, Shak S, Karasek MA, Davison PM, Goldstein IM	Prostaglandin I2 is not a major metabolite of arachidonic acid in cultured endothelial cells from human foreskin microvessels.	J. Clin. Invest.	74:3:914-9	1984	6432852		I F Charo, S Shak, M A Karasek, P M Davison, I M Goldstein	I F Charo	I M Goldstein		NHLBI NIH HHS; HL-28475
Detwiler TC, Charo IF, Feinman RD	Evidence that calcium regulates platelet function.	Thromb. Haemost.	40:2:207-11	1978	366791		T C Detwiler, I F Charo, R D Feinman	T C Detwiler	R D Feinman		NA
Charo IF, Feinman RD, Detwiler TC	Interrelations of platelet aggregation and secretion.	J. Clin. Invest.	60:4:866-73	1977	330568		I F Charo, R D Feinman, T C Detwiler	I F Charo	T C Detwiler		NA
Charo IF, Feinman RD, Detwiler TC, Smith JB, Ingerman CM, Silver MJ	Prostaglandin endoperoxides and thromboxane A2 can induce platelet aggregation in the absence of secretion.	Nature	269:5623:66-9	1977	895887		I F Charo, R D Feinman, T C Detwiler, J B Smith, C M Ingerman, M J Silver	I F Charo	M J Silver		NA
Feinman RD, Lubowsky J, Charo I, Zabinski MP	The lumi-aggregometer: a new instrument for simultaneous measurement of secretion and aggregation by platelets.	J. Lab. Clin. Med.	90:1:125-9	1977	874364		R D Feinman, J Lubowsky, I Charo, M P Zabinski	R D Feinman	M P Zabinski		NA
Charo IF, Feinman RD, Detwiler TC	Inhibition of platelet secretion by an antagonist of intracellular calcium.	Biochem. Biophys. Res. Commun.	72:4:1462-7	1976	793588		I F Charo, R D Feinman, T C Detwiler	I F Charo	T C Detwiler		NA
Can AS, Yildiz EA, Samur G, Rakicioğlu N, Pekcan G, Ozbayrakçi S, Palaoğlu KE, Gönen M, Bersot TP	Optimal waist:height ratio cut-off point for cardiometabolic risk factors in Turkish adults.	Public Health Nutr	13:4:488-95	2010	19781128		Ahmet Selçuk Can, Emine Akal Yildiz, Gülhan Samur, Neslişah Rakicioğlu, Gülden Pekcan, Sinan Ozbayrakçi, K Erhan Palaoğlu, Mithat Gönen, Thomas P Bersot	Ahmet Selçuk Can	Thomas P Bersot	Division of Endocrinology and Metabolism, Department of Medicine, Private Gayrettepe Florence Nightingale Hospital, Istanbul, Turkey. selcukcan@endokrinoloji.com	NA
Ling H, Waterworth DM, Stirnadel HA, Pollin TI, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Cohen JC, Grundy SM, Mooser VE, Mitchell BD	Genome-wide linkage and association analyses to identify genes influencing adiponectin levels: the GEMS Study.	Obesity (Silver Spring)	17:4:737-44	2009	19165155		Hua Ling, Dawn M Waterworth, Heide A Stirnadel, Toni I Pollin, Philip J Barter, Y Antero Kesäniemi, Robert W Mahley, Ruth McPherson, Gérard Waeber, Thomas P Bersot, Jonathan C Cohen, Scott M Grundy, Vincent E Mooser, Braxton D Mitchell	Hua Ling	Braxton D Mitchell	Department of Epidemiology and Preventive Medicine, University of Maryland, Baltimore, Maryland, USA.	NA
Can AS, Ozbayrakçi S, Palaoğlu KE, Bersot TP	Comparison between Turkish Cardiovascular Risk Platform and United States National Cholesterol Education Program Adult Treatment Panel III definitions of the metabolic syndrome in Turkish adults.	J Cardiometab Syndr	4:1:26-32	2009	19245513		Ahmet Selçuk Can, Sinan Ozbayrakçi, K Erhan Palaoğlu, Thomas P Bersot	Ahmet Selçuk Can	Thomas P Bersot	From the Department of Medicine, Faculty of Medicine, Istanbul Science University, Istanbul, Turkey.	NA
Can AS, Bersot TP, Gönen M, Pekcan G, Rakıcıoğlu N, Samur G, Yıldız EA	Anthropometric indices and their relationship with cardiometabolic risk factors in a sample of Turkish adults.	Public Health Nutr	12:4:538-46	2009	18489811		Ahmet Selcuk Can, Thomas P Bersot, Mithat Gönen, Gülden Pekcan, Neslişah Rakıcıoğlu, Gülhan Samur, Emine Akal Yıldız	Ahmet Selcuk Can	Emine Akal Yıldız	Department of Medicine, Istanbul Science University, Faculty of Medicine, Sişli, Istanbul, Turkey. selcukcan@endokrinoloji.com	NA
Can AS, Bersot TP	Analysis of agreement among definitions of metabolic syndrome in nondiabetic Turkish adults: a methodological study.	BMC Public Health	7:353	2007	18088443		Ahmet Selcuk Can, Thomas P Bersot	Ahmet Selcuk Can	Thomas P Bersot	Department of Medicine, Istanbul Science University, Faculty of Medicine, Esentepe, Sisli, Istanbul, Turkey. selcukcan@endokrinoloji.com	NA
Stirnadel H, Lin X, Ling H, Song K, Barter P, Kesäniemi YA, Mahley R, McPherson R, Waeber G, Bersot T, Cohen J, Grundy S, Mitchell B, Mooser V, Waterworth D	Genetic and phenotypic architecture of metabolic syndrome-associated components in dyslipidemic and normolipidemic subjects: the GEMS Study.	Atherosclerosis	197:2:868-76	2008	17888929		Heide Stirnadel, Xiwu Lin, Hua Ling, Kijoung Song, Philip Barter, Y Antero Kesäniemi, Robert Mahley, Ruth McPherson, Gérard Waeber, Thomas Bersot, Jonathan Cohen, Scott Grundy, Braxton Mitchell, Vincent Mooser, Dawn Waterworth	Heide Stirnadel	Dawn Waterworth	World Wide Epidemiology, GlaxoSmithKline, Harlow, UK.	NA
Barter P, McPherson YR, Song K, Kesäniemi YA, Mahley R, Waeber G, Bersot T, Mooser V, Waterworth D, Grundy SM	Serum insulin and inflammatory markers in overweight individuals with and without dyslipidemia.	J. Clin. Endocrinol. Metab.	92:6:2041-5	2007	17389699		Philip Barter, Y Ruth McPherson, Kijoung Song, Y Antero Kesäniemi, Robert Mahley, Gérard Waeber, Thomas Bersot, Vincent Mooser, Dawn Waterworth, Scott M Grundy	Philip Barter	Scott M Grundy	The Heart Research Institute, Camperdown, New South Wales, Australia. barterp@hri.org.au	NA
Bersot T, Haffner S, Harris WS, Kellick KA, Morris CM	Hypertriglyceridemia: management of atherogenic dyslipidemia.	J Fam Pract	55:7:S1-8	2006	16822443		Thomas Bersot, Steven Haffner, William S Harris, Kenneth A Kellick, Charlene M Morris	Thomas Bersot	Charlene M Morris	Gladstone Institute of Cardiovascular Disease, School of Medicine, University of California-San Francisco, San Francisco, CA, USA.	NA
Mahley RW, Bersot TP	High density lipoprotein cholesterol in coronary artery patients: is it as low as expected?	Anadolu Kardiyol Derg	6:1:94-6; author reply 96	2006	16524816		Robert W Mahley, Thomas P Bersot	Robert W Mahley	Thomas P Bersot		NA
Mahley RW, Can S, Ozbayrakçi S, Bersot TP, Tanir S, Palaoğlu KE, Pépin GM	Modulation of high-density lipoproteins in a population in istanbul, Turkey, with low levels of high-density lipoproteins.	Am. J. Cardiol.	96:4:547-55	2005	16098310		Robert W Mahley, Selçuk Can, Sinan Ozbayrakçi, Thomas P Bersot, Sibel Tanir, K Erhan Palaoğlu, Guy M Pépin	Robert W Mahley	Guy M Pépin	Gladstone Institute of Cardiovascular Disease, San Francisco, California. rmahley@gladstone.ucsf.edu	NHLBI NIH HHS; HL71027
Yu Y, Wyszynski DF, Waterworth DM, Wilton SD, Barter PJ, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Ma Q, Sharma SS, Montgomery DS, Middleton LT, Sundseth SS, Mooser V, Grundy SM, Farrer LA	Multiple QTLs influencing triglyceride and HDL and total cholesterol levels identified in families with atherogenic dyslipidemia.	J. Lipid Res.	46:10:2202-13	2005	16061952		Yi Yu, Diego F Wyszynski, Dawn M Waterworth, Steven D Wilton, Philip J Barter, Y Antero Kesäniemi, Robert W Mahley, Ruth McPherson, Gérard Waeber, Thomas P Bersot, Qianli Ma, Sanjay S Sharma, Douglas S Montgomery, Lefkos T Middleton, Scott S Sundseth, Vincent Mooser, Scott M Grundy, Lindsay A Farrer	Yi Yu	Lindsay A Farrer	Department of Medicine (Genetics Program), Boston University School of Medicine, Boston, MA, USA.	NA
Wyszynski DF, Waterworth DM, Barter PJ, Cohen J, Kesäniemi YA, Mahley RW, McPherson R, Waeber G, Bersot TP, Sharma SS, Nolan V, Middleton LT, Sundseth SS, Farrer LA, Mooser V, Grundy SM	Relation between atherogenic dyslipidemia and the Adult Treatment Program-III definition of metabolic syndrome (Genetic Epidemiology of Metabolic Syndrome Project).	Am. J. Cardiol.	95:2:194-8	2005	15642551		Diego F Wyszynski, Dawn M Waterworth, Philip J Barter, Jonathan Cohen, Y Antero Kesäniemi, Robert W Mahley, Ruth McPherson, Gérard Waeber, Thomas P Bersot, Sanjay S Sharma, Vikki Nolan, Lefkos T Middleton, Scott S Sundseth, Lindsay A Farrer, Vincent Mooser, Scott M Grundy	Diego F Wyszynski	Scott M Grundy	Department of Medicine (Genetics Program), Boston University School of Medicine, Boston, MA, USA.	NA
Bersot TP, Pépin GM, Mahley RW	Risk determination of dyslipidemia in populations characterized by low levels of high-density lipoprotein cholesterol.	Am. Heart J.	146:6:1052-9	2003	14660998		Thomas P Bersot, Guy M Pépin, Robert W Mahley	Thomas P Bersot	Robert W Mahley	Gladstone Institute, American Hospital, Istanbul, Turkey. tbersot@gladstone.ucsf.edu	NA
Raffaï RL, McPherson R, Weisgraber KH, Innerarity TL, Rassart E, Bersot TP, Milne RW	Antibody phenotyping test for the human apolipoprotein E2 isoform.	Clin. Chem.	49:9:1524-6	2003	12928236		Robert L Raffaï, Ruth McPherson, Karl H Weisgraber, Thomas L Innerarity, Eric Rassart, Thomas P Bersot, Ross W Milne	Robert L Raffaï	Ross W Milne	The Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, University of California, San Francisco, CA 94141-9100, USA. rrafai@gladstone.ucsf.edu	NHLBI NIH HHS; HL 41633
Bersot TP, Palaoğlu KE, Mahley RW	Managing dyslipidemia in Turkey: suggested guidelines for a population characterized by low levels of high density lipoprotein cholesterol.	Anadolu Kardiyol Derg	2:4:315-22	2002	12460830		Thomas P Bersot, K Erhan Palaoğlu, Robert W Mahley	Thomas P Bersot	Robert W Mahley	Gladstone Institute, Koç American Hospital, Istanbul, Turkey, and Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California, USA. tbersot@gladstone.ucsf.edu	NA
Shohet RV, Vega GL, Bersot TP, Mahley RW, Grundy SM, Guerra R, Cohen JC	Sources of variability in genetic association studies: insights from the analysis of hepatic lipase (LIPC).	Hum. Mutat.	19:5:536-42	2002	11968086		Ralph V Shohet, Gloria L Vega, Thomas P Bersot, Robert W Mahley, Scott M Grundy, Rudy Guerra, Jonathan C Cohen	Ralph V Shohet	Jonathan C Cohen	Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.	NCRR NIH HHS; M-01-RR-00633
Mahley RW, Arslan P, Pekcan G, Pépin GM, Ağaçdiken A, Karaağoğlu N, Rakicioğlu N, Nursal B, Dayanikli P, Palaoğlu KE, Bersot TP	Plasma lipids in Turkish children: impact of puberty, socioeconomic status, and nutrition on plasma cholesterol and HDL.	J. Lipid Res.	42:12:1996-2006	2001	11734572		R W Mahley, P Arslan, G Pekcan, G M Pépin, A Ağaçdiken, N Karaağoğlu, N Rakicioğlu, B Nursal, P Dayanikli, K E Palaoğlu, T P Bersot	R W Mahley	T P Bersot	Gladstone Institute of Cardiovascular Disease and Department of Medicine, University of California, San Francisco, CA 94141-9100, USA.	NA
Mahley RW, Pépin J, Palaoğlu KE, Malloy MJ, Kane JP, Bersot TP	Low levels of high density lipoproteins in Turks, a population with elevated hepatic lipase. High density lipoprotein characterization and gender-specific effects of apolipoprotein e genotype.	J. Lipid Res.	41:8:1290-301	2000	10946017		R W Mahley, J Pépin, K E Palaoğlu, M J Malloy, J P Kane, T P Bersot	R W Mahley	T P Bersot	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141, USA.	NHLBI NIH HHS; HL31210
Bersot TP, Vega GL, Grundy SM, Palaoglu KE, Atagündüz P, Ozbayrakçi S, Gökdemir O, Mahley RW	Elevated hepatic lipase activity and low levels of high density lipoprotein in a normotriglyceridemic, nonobese Turkish population.	J. Lipid Res.	40:3:432-8	1999	10064731		T P Bersot, G L Vega, S M Grundy, K E Palaoglu, P Atagündüz, S Ozbayrakçi, O Gökdemir, R W Mahley	T P Bersot	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.	NCRR NIH HHS; MO1-RR-00633
Vega GL, Gao J, Bersot TP, Mahley RW, Verstraete R, Grundy SM, White A, Cohen JC	The -514 polymorphism in the hepatic lipase gene (LIPC) does not influence androgen-mediated stimulation of hepatic lipase activity.	J. Lipid Res.	39:7:1520-4	1998	9684756		G L Vega, J Gao, T P Bersot, R W Mahley, R Verstraete, S M Grundy, A White, J C Cohen	G L Vega	J C Cohen	The Center for Human Nutrition, Department of Clinical Nutrition, University of Texas Southwestern Medical Center at Dallas, 75235, USA.	NCRR NIH HHS; M-01-RR-00633
Bersot TP, Russell SJ, Thatcher SR, Pomernacki NK, Mahley RW, Weisgraber KH, Innerarity TL, Fox CS	A unique haplotype of the apolipoprotein B-100 allele associated with familial defective apolipoprotein B-100 in a Chinese man discovered during a study of the prevalence of this disorder.	J. Lipid Res.	34:7:1149-54	1993	8371062		T P Bersot, S J Russell, S R Thatcher, N K Pomernacki, R W Mahley, K H Weisgraber, T L Innerarity, C S Fox	T P Bersot	C S Fox	Gladstone Institute of Cardiovascular Disease, San Francisco General Hospital, CA.	NHLBI NIH HHS; HL41633
Innerarity TL, Mahley RW, Weisgraber KH, Bersot TP, Krauss RM, Vega GL, Grundy SM, Friedl W, Davignon J, McCarthy BJ	Familial defective apolipoprotein B-100: a mutation of apolipoprotein B that causes hypercholesterolemia.	J. Lipid Res.	31:8:1337-49	1990	2280177		T L Innerarity, R W Mahley, K H Weisgraber, T P Bersot, R M Krauss, G L Vega, S M Grundy, W Friedl, J Davignon, B J McCarthy	T L Innerarity	B J McCarthy	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL-41633
Rall SC, Newhouse YM, Clarke HR, Weisgraber KH, McCarthy BJ, Mahley RW, Bersot TP	Type III hyperlipoproteinemia associated with apolipoprotein E phenotype E3/3. Structure and genetics of an apolipoprotein E3 variant.	J. Clin. Invest.	83:4:1095-101	1989	2539388		S C Rall, Y M Newhouse, H R Clarke, K H Weisgraber, B J McCarthy, R W Mahley, T P Bersot	S C Rall	T P Bersot	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, San Francisco, California 94140-0608.	NA
Bersot TP, Innerarity TL, Pitas RE, Rall SC, Weisgraber KH, Mahley RW	Fat feeding in humans induces lipoproteins of density less than 1.006 that are enriched in apolipoprotein [a] and that cause lipid accumulation in macrophages.	J. Clin. Invest.	77:2:622-30	1986	2935560		T P Bersot, T L Innerarity, R E Pitas, S C Rall, K H Weisgraber, R W Mahley	T P Bersot	R W Mahley		NCRR NIH HHS; RR00083
Innerarity TL, Hui DY, Bersot TP, Mahley RW	Type III hyperlipoproteinemia: a focus on lipoprotein receptor-apolipoprotein E2 interactions.	Adv. Exp. Med. Biol.	201:273-88	1986	3026150		T L Innerarity, D Y Hui, T P Bersot, R W Mahley	T L Innerarity	R W Mahley		NA
Cheng CF, Bensadoun A, Bersot T, Hsu JS, Melford KH	Purification and characterization of human lipoprotein lipase and hepatic triglyceride lipase. Reactivity with monoclonal antibodies to hepatic triglyceride lipase.	J. Biol. Chem.	260:19:10720-7	1985	4030767		C F Cheng, A Bensadoun, T Bersot, J S Hsu, K H Melford	C F Cheng	K H Melford		NCRR NIH HHS; RR00083
Innerarity TL, Bersot TP, Arnold KS, Weisgraber KH, Davis PA, Forte TM, Mahley RW	Receptor binding activity of high-density lipoproteins containing apoprotein E from abetalipoproteinemic and normal neonate plasma.	Metab. Clin. Exp.	33:2:186-95	1984	6319954		T L Innerarity, T P Bersot, K S Arnold, K H Weisgraber, P A Davis, T M Forte, R W Mahley	T L Innerarity	R W Mahley		NHLBI NIH HHS; HL-18574
Rall SC, Weisgraber KH, Innerarity TL, Bersot TP, Mahley RW, Blum CB	Identification of a new structural variant of human apolipoprotein E, E2(Lys146 leads to Gln), in a type III hyperlipoproteinemic subject with the E3/2 phenotype.	J. Clin. Invest.	72:4:1288-97	1983	6313758		S C Rall, K H Weisgraber, T L Innerarity, T P Bersot, R W Mahley, C B Blum	S C Rall	C B Blum		NHLBI NIH HHS; HL 21006
Bersot TP, Innerarity TL, Mahley RW, Havel RJ	Cholesteryl ester accumulation in mouse peritoneal macrophages induced by beta-migrating very low density lipoproteins from patients with atypical dysbetalipoproteinemia.	J. Clin. Invest.	72:3:1024-33	1983	6309903		T P Bersot, T L Innerarity, R W Mahley, R J Havel	T P Bersot	R J Havel		NCRR NIH HHS; RR 00083
Havel RJ, Kotite L, Kane JP, Tun P, Bersot T	Atypical familial dysbetalipoproteinemia associated with apolipoprotein phenotype E3/3.	J. Clin. Invest.	72:1:379-87	1983	6860421		R J Havel, L Kotite, J P Kane, P Tun, T Bersot	R J Havel	T Bersot		NCRR NIH HHS; RR00083
Weisgraber KH, Rall SC, Bersot TP, Mahley RW, Franceschini G, Sirtori CR	Apolipoprotein A-IMilano. Detection of normal A-I in affected subjects and evidence for a cysteine for arginine substitution in the variant A-I.	J. Biol. Chem.	258:4:2508-13	1983	6401735		K H Weisgraber, S C Rall, T P Bersot, R W Mahley, G Franceschini, C R Sirtori	K H Weisgraber	C R Sirtori		NHLBI NIH HHS; HL27455
Weisgraber KH, Bersot TP, Mahley RW, Franceschini G, Sirtori CR	A-Imilano apoprotein. Isolation and characterization of a cysteine-containing variant of the A-I apoprotein from human high density lipoproteins.	J. Clin. Invest.	66:5:901-7	1980	6776144		K H Weisgraber, T P Bersot, R W Mahley, G Franceschini, C R Sirtori	K H Weisgraber	C R Sirtori		NA
Weisgraber KH, Bersot TP, Mahley RW	Isolation and characterization of an apoprotein from the d less than 1.006 lipoproteins of human and canine lymph homologous with the rat A-IV apoprotein.	Biochem. Biophys. Res. Commun.	85:1:287-92	1978	217374		K H Weisgraber, T P Bersot, R W Mahley	K H Weisgraber	R W Mahley		NA
Mahley RW, Innerarity TL, Bersot TP, Lipson A, Margolis S	Alterations in human high-density lipoproteins, with or without increased plasma-cholesterol, induced by diets high in cholesterol.	Lancet	2:8094:807-9	1978	81362		R W Mahley, T L Innerarity, T P Bersot, A Lipson, S Margolis	R W Mahley	S Margolis		NA
Innerarity TL, Mahley RW, Weisgraber KH, Bersot TP	Apoprotein (E--A-II) complex of human plasma lipoproteins. II. Receptor binding activity of a high density lipoprotein subfraction modulated by the apo(E--A-II) complex.	J. Biol. Chem.	253:17:6289-95	1978	210175		T L Innerarity, R W Mahley, K H Weisgraber, T P Bersot	T L Innerarity	T P Bersot		NA
Bersot TP, Mahley RW, Brown MS, Goldstein JL	Interaction of swine lipoproteins with the low density lipoprotein receptor in human fibroblasts.	J. Biol. Chem.	251:8:2395-8	1976	177413		T P Bersot, R W Mahley, M S Brown, J L Goldstein	T P Bersot	J L Goldstein		NA
Herbert PN, Windmueller HG, Bersot TP, Shulman RS	Characterization of the rat apolipoproteins. I. The low molecular weight proteins of rat plasma high density lipoproteins.	J. Biol. Chem.	249:18:5718-24	1974	4369853		P N Herbert, H G Windmueller, T P Bersot, R S Shulman	P N Herbert	R S Shulman		NA
Mahley RW, Bersot TP, LeQuire VS, Levy RI, Windmueller HG, Brown WV	Identity of very low density lipoprotein apoproteins of plasma and liver Golgi apparatus.	Science	168:3929:380-2	1970	4985196		R W Mahley, T P Bersot, V S LeQuire, R I Levy, H G Windmueller, W V Brown	R W Mahley	W V Brown		NA
Xu T, Zhang M, Laurent T, Xie M, Ding S	Concise review: chemical approaches for modulating lineage-specific stem cells and progenitors.	Stem Cells Transl Med	2:5:355-61	2013	23580542		Tao Xu, Mingliang Zhang, Timothy Laurent, Min Xie, Sheng Ding	Tao Xu	Sheng Ding	Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.	NA
Li J, Huang NF, Zou J, Laurent TJ, Lee JC, Okogbaa J, Cooke JP, Ding S	Conversion of human fibroblasts to functional endothelial cells by defined factors.	Arterioscler. Thromb. Vasc. Biol.	33:6:1366-75	2013	23520160		Jun Li, Ngan F Huang, Jun Zou, Timothy J Laurent, Jerry C Lee, Janet Okogbaa, John P Cooke, Sheng Ding	Jun Li	Sheng Ding	From the Gladstone Institute of Cardiovascular Disease (J.L., J.Z., T.J.L., S.D.) and Department of Pharmaceutical Chemistry (S.D.), University of California, San Francisco, CA.	NA
Ma T, Xie M, Laurent T, Ding S	Progress in the reprogramming of somatic cells.	Circ. Res.	112:3:562-74	2013	23371904		Tianhua Ma, Min Xie, Timothy Laurent, Sheng Ding	Tianhua Ma	Sheng Ding	Department of Pharmaceutical Chemistry, Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA.	NA
Li W, Jiang K, Wei W, Shi Y, Ding S	Chemical approaches to studying stem cell biology.	Cell Res.	23:1:81-91	2013	23266890		Wenlin Li, Kai Jiang, Wanguo Wei, Yan Shi, Sheng Ding	Wenlin Li	Sheng Ding	Department of Cell Biology, Second Military Medical University, Shanghai 200433, China.	NA
Zhang Y, Li W, Laurent T, Ding S	Small molecules, big roles -- the chemical manipulation of stem cell fate and somatic cell reprogramming.	J. Cell. Sci.	125:Pt 23:5609-20	2012	23420199		Yu Zhang, Wenlin Li, Timothy Laurent, Sheng Ding	Yu Zhang	Sheng Ding	Gladstone Institute of Cardiovascular Disease, Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94158, USA.	NHLBI NIH HHS; HL107436
Zhao J, Sun W, Cho HM, Ouyang H, Li W, Lin Y, Do J, Zhang L, Ding S, Liu Y, Lu P, Zhang K	Integration and long distance axonal regeneration in the central nervous system from transplanted primitive neural stem cells.	J. Biol. Chem.	288:1:164-8	2013	23155053		Jiagang Zhao, Woong Sun, Hyo Min Cho, Hong Ouyang, Wenlin Li, Ying Lin, Jiun Do, Liangfang Zhang, Sheng Ding, Yizhi Liu, Paul Lu, Kang Zhang	Jiagang Zhao	Kang Zhang	State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510275, China.	NEI NIH HHS; R01 EY021374
Nie B, Wang H, Laurent T, Ding S	Cellular reprogramming: a small molecule perspective.	Curr. Opin. Cell Biol.	24:6:784-92	2012	22959962		Baoming Nie, Haixia Wang, Timothy Laurent, Sheng Ding	Baoming Nie	Sheng Ding	Gladstone Institute of Cardiovascular Disease, Department of Pharmaceutical Chemistry, University of California, San Francisco, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Liu K, Ding S	Target practice: modeling tumors with stem cells.	Cell	149:6:1185-7	2012	22682241		Kai Liu, Sheng Ding	Kai Liu	Sheng Ding	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, 94158, USA.	NA
Ukrohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M	Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells.	Stem Cells Transl Med	1:2:96-109	2012	22532929		Tim U Ukrohne, Peter D Westenskow, Toshihide Kurihara, David F Friedlander, Mandy Lehmann, Alison L Dorsey, Wenlin Li, Saiyong Zhu, Andrew Schultz, Junhua Wang, Gary Siuzdak, Sheng Ding, Martin Friedlander	Tim U Ukrohne	Martin Friedlander	Department of Cell Biology, The Scripps Research Institute, La Jolla, California 92037, USA.	NEI NIH HHS; R01 EY011254-14
Li W, Jiang K, Ding S	Concise review: A chemical approach to control cell fate and function.	Stem Cells	30:1:61-8	2012	22028211		Wenlin Li, Kai Jiang, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, San Diego, California, USA.	NA
Shen Y, Shi C, Wei W, Yu W, Li W, Yang Y, Xu J, Ying W, Sui X, Fang L, Lin W, Yang H, Ding S, Shen H, Shi Y, Deng H	The heterogeneity and dynamic equilibrium of rat embryonic stem cells.	Cell Res.	21:7:1143-7	2011	21670743		Yan Shen, Cheng Shi, Wei Wei, Weidong Yu, Wenlin Li, Yang Yang, Jun Xu, Wenqin Ying, Xin Sui, Lingling Fang, Weiwei Lin, Huan Yang, Sheng Ding, Huan Shen, Yan Shi, Hongkui Deng	Yan Shen	Hongkui Deng		NA
Xu T, Wang X, Zhong B, Nurieva RI, Ding S, Dong C	Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein.	J. Biol. Chem.	286:26:22707-10	2011	21566134		Tao Xu, Xiaohu Wang, Bo Zhong, Roza I Nurieva, Sheng Ding, Chen Dong	Tao Xu	Chen Dong	Gladstone Institute of Cardiovascular Disease, Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94158, USA.	NIAID NIH HHS; R01 AI083761-04
Li W, Sun W, Zhang Y, Wei W, Ambasudhan R, Xia P, Talantova M, Lin T, Kim J, Wang X, Kim WR, Lipton SA, Zhang K, Ding S	Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors.	Proc. Natl. Acad. Sci. U.S.A.	108:20:8299-304	2011	21525408		Wenlin Li, Woong Sun, Yu Zhang, Wanguo Wei, Rajesh Ambasudhan, Peng Xia, Maria Talantova, Tongxiang Lin, Janghwan Kim, Xiaolei Wang, Woon Ryoung Kim, Stuart A Lipton, Kang Zhang, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.	NEI NIH HHS; R01 EY021374-02
Li W, Ding S	Human pluripotent stem cells: decoding the naïve state.	Sci Transl Med	3:76:76ps10	2011	21451122		Wenlin Li, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.	NA
Zhu S, Ma T, Li J, Ding S	Recent advances in chemically induced reprogramming.	Cell Cycle	10:6:871-2	2011	21368574		Saiyong Zhu, Tianhua Ma, Jun Li, Sheng Ding	Saiyong Zhu	Sheng Ding		NA
Yuan X, Li W, Ding S	Small molecules in cellular reprogramming and differentiation.	Prog Drug Res	67:253-66	2011	21141734		Xu Yuan, Wenlin Li, Sheng Ding	Xu Yuan	Sheng Ding	Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.	NA
Zhu S, Li W, Zhou H, Wei W, Ambasudhan R, Lin T, Kim J, Zhang K, Ding S	Reprogramming of human primary somatic cells by OCT4 and chemical compounds.	Cell Stem Cell	7:6:651-5	2010	21112560		Saiyong Zhu, Wenlin Li, Hongyan Zhou, Wanguo Wei, Rajesh Ambasudhan, Tongxiang Lin, Janghwan Kim, Kang Zhang, Sheng Ding	Saiyong Zhu	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.	NICHD NIH HHS; R01 HD064610
Zhou H, Li W, Zhu S, Joo JY, Do JT, Xiong W, Kim JB, Zhang K, Schöler HR, Ding S	Conversion of mouse epiblast stem cells to an earlier pluripotency state by small molecules.	J. Biol. Chem.	285:39:29676-80	2010	20705612		Hongyan Zhou, Wenlin Li, Saiyong Zhu, Jin Young Joo, Jeong Tae Do, Wen Xiong, Jeong Beom Kim, Kang Zhang, Hans R Schöler, Sheng Ding	Hongyan Zhou	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, USA.	NEI NIH HHS; R01 EY021374-02
Li W, Ding S	Generation of novel rat and human pluripotent stem cells by reprogramming and chemical approaches.	Methods Mol. Biol.	636:293-300	2010	20336530		Wenlin Li, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.	NA
Li W, Zhou H, Abujarour R, Zhu S, Young Joo J, Lin T, Hao E, Schöler HR, Hayek A, Ding S	Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2.	Stem Cells	27:12:2992-3000	2009	19839055		Wenlin Li, HongYan Zhou, Ramzey Abujarour, Saiyong Zhu, Jin Young Joo, Tongxiang Lin, Ergeng Hao, Hans R Schöler, Alberto Hayek, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, USA.	NICHD NIH HHS; R01 HD064610
Li W, Ding S	Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming.	Trends Pharmacol. Sci.	31:1:36-45	2010	19896224		Wenlin Li, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.	NA
Lin T, Ambasudhan R, Yuan X, Li W, Hilcove S, Abujarour R, Lin X, Hahm HS, Hao E, Hayek A, Ding S	A chemical platform for improved induction of human iPSCs.	Nat. Methods	6:11:805-8	2009	19838168		Tongxiang Lin, Rajesh Ambasudhan, Xu Yuan, Wenlin Li, Simon Hilcove, Ramzey Abujarour, Xiangyi Lin, Heung Sik Hahm, Ergeng Hao, Alberto Hayek, Sheng Ding	Tongxiang Lin	Sheng Ding	Department of Chemistry, The Scripps Research Institute, La Jolla, California, USA.	NICHD NIH HHS; R01 HD064610
Li W, Wei W, Zhu S, Zhu J, Shi Y, Lin T, Hao E, Hayek A, Deng H, Ding S	Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors.	Cell Stem Cell	4:1:16-9	2009	19097958		Wenlin Li, Wei Wei, Saiyong Zhu, Jinliang Zhu, Yan Shi, Tongxiang Lin, Ergeng Hao, Alberto Hayek, Hongkui Deng, Sheng Ding	Wenlin Li	Sheng Ding	Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.	NA
Chen S, Takanashi S, Zhang Q, Xiong W, Zhu S, Peters EC, Ding S, Schultz PG	Reversine increases the plasticity of lineage-committed mammalian cells.	Proc. Natl. Acad. Sci. U.S.A.	104:25:10482-7	2007	17566101		Shuibing Chen, Shinichi Takanashi, Qisheng Zhang, Wen Xiong, Shoutian Zhu, Eric C Peters, Sheng Ding, Peter G Schultz	Shuibing Chen	Peter G Schultz	Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.	NICHD NIH HHS; R21HD47452
Chen S, Hilcove S, Ding S	Exploring stem cell biology with small molecules.	Mol Biosyst	2:1:18-24	2006	16880919		Shuibing Chen, Simon Hilcove, Sheng Ding	Shuibing Chen	Sheng Ding	Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.	NA
Ding S, Wu TY, Brinker A, Peters EC, Hur W, Gray NS, Schultz PG	Synthetic small molecules that control stem cell fate.	Proc. Natl. Acad. Sci. U.S.A.	100:13:7632-7	2003	12794184		Sheng Ding, Tom Y H Wu, Achim Brinker, Eric C Peters, Wooyoung Hur, Nathanael S Gray, Peter G Schultz	Sheng Ding	Peter G Schultz	Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.	NA
Trnka TM, Morgan JP, Sanford MS, Wilhelm TE, Scholl M, Choi TL, Ding S, Day MW, Grubbs RH	Synthesis and activity of ruthenium alkylidene complexes coordinated with phosphine and N-heterocyclic carbene ligands.	J. Am. Chem. Soc.	125:9:2546-58	2003	12603143		Tina M Trnka, John P Morgan, Melanie S Sanford, Thomas E Wilhelm, Matthias Scholl, Tae-Lim Choi, Sheng Ding, Michael W Day, Robert H Grubbs	Tina M Trnka	Robert H Grubbs	Arnold and Mabel Beckman Laboratory of Chemical Synthesis, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.	NA
Peng CT, Yang ZC, Ding SF	Prediction of retention indexes. II. Structure-retention index relationship on polar columns.	J. Chromatogr.	586:1:85-112	1991	1806557		C T Peng, Z C Yang, S F Ding	C T Peng	S F Ding	Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco 94143-0446.	NCI NIH HHS; CA33537
Peng CT, Ding SF, Hua RL, Yang ZC	Prediction of retention indexes. I. Structure-retention index relationship on apolar columns.	J. Chromatogr.	436:2:137-72	1988	3356761		C T Peng, S F Ding, R L Hua, Z C Yang	C T Peng	Z C Yang	Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco 94143.	NCI NIH HHS; CA 33537
Pourquié O, Bruneau B, Götz M, Keller G, Smith A	Stem cells and regeneration: a special issue.	Development	140:12:2445	2013	23715535		Olivier Pourquié, Benoit Bruneau, Magdalena Götz, Gordon Keller, Austin Smith	Olivier Pourquié	Austin Smith	Development.	NA
Bruneau BG	Signaling and transcriptional networks in heart development and regeneration.	Cold Spring Harb Perspect Biol	5:3:a008292	2013	23457256		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, and Department of Pediatrics and Cardiovascular Research Institute, University of California, San Francisco, California 94158, USA. bbruneau@gladstone.ucsf.edu	NA
Star EN, Zhu M, Shi Z, Liu H, Pashmforoush M, Sauve Y, Bruneau BG, Chow RL	Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6.	Development	139:24:4644-55	2012	23172916		Erin N Star, Minyan Zhu, Zhiwei Shi, Haiquan Liu, Mohammad Pashmforoush, Yves Sauve, Benoit G Bruneau, Robert L Chow	Erin N Star	Robert L Chow	Department of Biology, University of Victoria, Victoria, BC V8W 3N5, Canada.	Canadian Institutes of Health Research; 
Gaborit N, Sakuma R, Wylie JN, Kim KH, Zhang SS, Hui CC, Bruneau BG	Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology.	Development	139:21:4007-19	2012	22992950		Nathalie Gaborit, Rui Sakuma, John N Wylie, Kyoung-Han Kim, Shan-Shan Zhang, Chi-Chung Hui, Benoit G Bruneau	Nathalie Gaborit	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	Canadian Institutes of Health Research; 
Kim KH, Rosen A, Bruneau BG, Hui CC, Backx PH	Iroquois homeodomain transcription factors in heart development and function.	Circ. Res.	110:11:1513-24	2012	22628575		Kyoung-Han Kim, Anna Rosen, Benoit G Bruneau, Chi-chung Hui, Peter H Backx	Kyoung-Han Kim	Peter H Backx	Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, Ontario, Canada.	Canadian Institutes of Health Research; 
Delgado-Olguín P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG	Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.	Nat. Genet.	44:3:343-7	2012	22267199		Paul Delgado-Olguín, Yu Huang, Xue Li, Danos Christodoulou, Christine E Seidman, J G Seidman, Alexander Tarakhovsky, Benoit G Bruneau	Paul Delgado-Olguín	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NHLBI NIH HHS; U01HL098179
Chang CP, Bruneau BG	Epigenetics and cardiovascular development.	Annu. Rev. Physiol.	74:41-68	2012	22035349		Ching-Pin Chang, Benoit G Bruneau	Ching-Pin Chang	Benoit G Bruneau	Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, USA. chingpin@stanford.edu	NA
Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH	Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.	Proc. Natl. Acad. Sci. U.S.A.	108:33:13576-81	2011	21825130		Shan-Shan Zhang, Kyoung-Han Kim, Anna Rosen, James W Smyth, Rui Sakuma, Paul Delgado-Olguín, Mark Davis, Neil C Chi, Vijitha Puviindran, Nathalie Gaborit, Tatyana Sukonnik, John N Wylie, Koroboshka Brand-Arzamendi, Gerrie P Farman, Jieun Kim, Robert A Rose, Phillip A Marsden, Yonghong Zhu, Yu-Qing Zhou, Lucile Miquerol, R Mark Henkelman, Didier Y R Stainier, Robin M Shaw, Chi-chung Hui, Benoit G Bruneau, Peter H Backx	Shan-Shan Zhang	Peter H Backx	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	Canadian Institutes of Health Research; 
Bruneau BG	Atrial natriuretic factor in the developing heart: a signpost for cardiac morphogenesis.	Can. J. Physiol. Pharmacol.	89:8:533-7	2011	21806510		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA. bbruneau@gladstone.ucsf.edu	NA
Wyngaarden LA, Delgado-Olguin P, Su IH, Bruneau BG, Hopyan S	Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb.	Development	138:17:3759-67	2011	21795281		Laurie A Wyngaarden, Paul Delgado-Olguin, I-hsin Su, Benoit G Bruneau, Sevan Hopyan	Laurie A Wyngaarden	Sevan Hopyan	Developmental and Stem Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.	NA
Takeuchi JK, Lou X, Alexander JM, Sugizaki H, Delgado-Olguín P, Holloway AK, Mori AD, Wylie JN, Munson C, Zhu Y, Zhou YQ, Yeh RF, Henkelman RM, Harvey RP, Metzger D, Chambon P, Stainier DY, Pollard KS, Scott IC, Bruneau BG	Chromatin remodelling complex dosage modulates transcription factor function in heart development.	Nat Commun	2:187	2011	21304516		Jun K Takeuchi, Xin Lou, Jeffrey M Alexander, Hiroe Sugizaki, Paul Delgado-Olguín, Alisha K Holloway, Alessandro D Mori, John N Wylie, Chantilly Munson, Yonghong Zhu, Yu-Qing Zhou, Ru-Fang Yeh, R Mark Henkelman, Richard P Harvey, Daniel Metzger, Pierre Chambon, Didier Y R Stainier, Katherine S Pollard, Ian C Scott, Benoit G Bruneau	Jun K Takeuchi	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL54737
Delgado-Olguín P, Brand-Arzamendi K, Scott IC, Jungblut B, Stainier DY, Bruneau BG, Recillas-Targa F	CTCF promotes muscle differentiation by modulating the activity of myogenic regulatory factors.	J. Biol. Chem.	286:14:12483-94	2011	21288905		Paul Delgado-Olguín, Koroboshka Brand-Arzamendi, Ian C Scott, Benno Jungblut, Didier Y Stainier, Benoit G Bruneau, Félix Recillas-Targa	Paul Delgado-Olguín	Félix Recillas-Targa	Gladstone Institute of Cardiovascular Disease, Department of Biochemistry and Biophysics, University of California San Francisco, San Francisco, CA 94158, USA.	NHLBI NIH HHS; HL54737
Nadeau M, Georges RO, Laforest B, Yamak A, Lefebvre C, Beauregard J, Paradis P, Bruneau BG, Andelfinger G, Nemer M	An endocardial pathway involving Tbx5, Gata4, and Nos3 required for atrial septum formation.	Proc. Natl. Acad. Sci. U.S.A.	107:45:19356-61	2010	20974940		Mathieu Nadeau, Romain O Georges, Brigitte Laforest, Abir Yamak, Chantal Lefebvre, Janie Beauregard, Pierre Paradis, Benoit G Bruneau, Gregor Andelfinger, Mona Nemer	Mathieu Nadeau	Mona Nemer	Research Unit in Cardiac Growth and Differentiation and Molecular Biology Program, Université de Montréal, Montréal, QC, Canada H3C 3J7.	Canadian Institutes of Health Research; MOP13057
Puskaric S, Schmitteckert S, Mori AD, Glaser A, Schneider KU, Bruneau BG, Blaschke RJ, Steinbeisser H, Rappold G	Shox2 mediates Tbx5 activity by regulating Bmp4 in the pacemaker region of the developing heart.	Hum. Mol. Genet.	19:23:4625-33	2010	20858598		Sandra Puskaric, Stefanie Schmitteckert, Alessandro D Mori, Anne Glaser, Katja U Schneider, Benoit G Bruneau, Rüdiger J Blaschke, Herbert Steinbeisser, Gudrun Rappold	Sandra Puskaric	Gudrun Rappold	Department of Human Molecular Genetics, Division of Developmental Genetics, Institute of Human Genetics,University of Heidelberg, Heidelberg, Germany.	NA
Bruneau BG	Chromatin remodeling in heart development.	Curr. Opin. Genet. Dev.	20:5:505-11	2010	20702085		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, United States. bbruneau@gladstone.ucsf.edu	NA
Bruneau BG	Epigenetic regulation of the cardiovascular system: introduction to a review series.	Circ. Res.	107:3:324-6	2010	20689071		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. bbruneau@gladstone.ucsf.edu	NHLBI NIH HHS; R01 HL085860-05
Alexander JM, Bruneau BG	Lessons for cardiac regeneration and repair through development.	Trends Mol Med	16:9:426-34	2010	20692205		Jeffrey M Alexander, Benoit G Bruneau	Jeffrey M Alexander	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; U01 HL100406
Kuo YM, Li Z, Jiao Y, Gaborit N, Pani AK, Orrison BM, Bruneau BG, Giasson BI, Smeyne RJ, Gershon MD, Nussbaum RL	Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes.	Hum. Mol. Genet.	19:9:1633-50	2010	20106867		Yien-Ming Kuo, Zhishan Li, Yun Jiao, Nathalie Gaborit, Amar K Pani, Bonnie M Orrison, Benoit G Bruneau, Benoit I Giasson, Richard J Smeyne, Michael D Gershon, Robert L Nussbaum	Yien-Ming Kuo	Robert L Nussbaum	Department of Medicine, University of California San Francisco, San Francisco, CA 94143, USA.	NINDS NIH HHS; NS15547
Fouladkou F, Lu C, Jiang C, Zhou L, She Y, Walls JR, Kawabe H, Brose N, Henkelman RM, Huang A, Bruneau BG, Rotin D	The ubiquitin ligase Nedd4-1 is required for heart development and is a suppressor of thrombospondin-1.	J. Biol. Chem.	285:9:6770-80	2010	20026598		Fatemeh Fouladkou, Chen Lu, Chong Jiang, Limei Zhou, Yimin She, Jonathon R Walls, Hiroshi Kawabe, Nils Brose, R M Henkelman, Annie Huang, Benoit G Bruneau, Daniela Rotin	Fatemeh Fouladkou	Daniela Rotin	Program in Cell Biology and the Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.	Canadian Institutes of Health Research; MOP 13494
Koshiba-Takeuchi K, Mori AD, Kaynak BL, Cebra-Thomas J, Sukonnik T, Georges RO, Latham S, Beck L, Beck L, Henkelman RM, Black BL, Olson EN, Wade J, Takeuchi JK, Nemer M, Gilbert SF, Bruneau BG	Reptilian heart development and the molecular basis of cardiac chamber evolution.	Nature	461:7260:95-8	2009	19727199		Kazuko Koshiba-Takeuchi, Alessandro D Mori, Bogac L Kaynak, Judith Cebra-Thomas, Tatyana Sukonnik, Romain O Georges, Stephany Latham, Laurel Beck, Laural Beck, R Mark Henkelman, Brian L Black, Eric N Olson, Juli Wade, Jun K Takeuchi, Mona Nemer, Scott F Gilbert, Benoit G Bruneau	Kazuko Koshiba-Takeuchi	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL064658-10
Riazi AM, Takeuchi JK, Hornberger LK, Zaidi SH, Amini F, Coles J, Bruneau BG, Van Arsdell GS	NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes.	PLoS ONE	4:5:e5698	2009	19479054		Ali M Riazi, Jun K Takeuchi, Lisa K Hornberger, Syed Hassan Zaidi, Fariba Amini, John Coles, Benoit G Bruneau, Glen S Van Arsdell	Ali M Riazi	Glen S Van Arsdell	Labatt Family Heart Centre, Hospital for Sick Children, Toronto, Ontario, Canada. ali.riazi@sickkids.ca	NA
Takeuchi JK, Bruneau BG	Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors.	Nature	459:7247:708-11	2009	19396158		Jun K Takeuchi, Benoit G Bruneau	Jun K Takeuchi	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. takeuchi.j.ab@m.titech.ac.jp	NHLBI NIH HHS; U01 HL100406
Zhu Y, Gramolini AO, Walsh MA, Zhou YQ, Slorach C, Friedberg MK, Takeuchi JK, Sun H, Henkelman RM, Backx PH, Redington AN, Maclennan DH, Bruneau BG	Tbx5-dependent pathway regulating diastolic function in congenital heart disease.	Proc. Natl. Acad. Sci. U.S.A.	105:14:5519-24	2008	18378906		Yonghong Zhu, Anthony O Gramolini, Mark A Walsh, Yu-Qing Zhou, Cameron Slorach, Mark K Friedberg, Jun K Takeuchi, Hui Sun, R Mark Henkelman, Peter H Backx, Andrew N Redington, David H Maclennan, Benoit G Bruneau	Yonghong Zhu	Benoit G Bruneau	Programme in Developmental and Stem Cell Biology, Division of Cardiology and Labatt Family Heart Centre, Programme in Physiology and Experimental Medicine, and Mouse Imaging Centre, Hospital for Sick Children, Toronto, ON, Canada.	NA
Bruneau BG	The developmental genetics of congenital heart disease.	Nature	451:7181:943-8	2008	18288184		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Gladstone Institute of Cardiovascular Disease, and Department of Pediatrics, University of California San Francisco, 1650 Owens Street, San Francisco, California 94158, USA. bbruneau@gladstone.ucsf.edu	NA
Feintuch A, Zhu Y, Bishop J, Davidson L, Dazai J, Bruneau BG, Henkelman RM	4D cardiac MRI in the mouse.	NMR Biomed	20:3:360-5	2007	17451168		Akiva Feintuch, Yonghong Zhu, Jonathan Bishop, Lorinda Davidson, Jun Dazai, Benoit G Bruneau, R Mark Henkelman	Akiva Feintuch	R Mark Henkelman	Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada. feintuch@phenogenomics.ca	NA
Bruneau BG, Black BL	The heart's Da Vinci code: a Renaissance at Keystone.	Development	134:9:1631-3	2007	17395645		Benoit G Bruneau, Brian L Black	Benoit G Bruneau	Brian L Black	Gladstone Institute of Cardiovascular Disease and Department of Pediatrics, University of California, San Francisco, CA 94158, USA. bbruneau@gladstone.ucsf.edu	NA
Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG	Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry.	Proc. Natl. Acad. Sci. U.S.A.	104:3:846-51	2007	17210915		Jun K Takeuchi, Heiko Lickert, Brent W Bisgrove, Xin Sun, Masamichi Yamamoto, Kallayanee Chawengsaksophak, Hiroshi Hamada, H Joseph Yost, Janet Rossant, Benoit G Bruneau	Jun K Takeuchi	Benoit G Bruneau	Department of Cardiovascular Research, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada.	NA
Takeuchi JK, Bruneau BG	Irxl1, a divergent Iroquois homeobox family transcription factor gene.	Gene Expr. Patterns	7:1-2:51-6	2007	16824806		Jun K Takeuchi, Benoit G Bruneau	Jun K Takeuchi	Benoit G Bruneau	Programs in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, Ont., Canada.	NA
Mori AD, Zhu Y, Vahora I, Nieman B, Koshiba-Takeuchi K, Davidson L, Pizard A, Seidman JG, Seidman CE, Chen XJ, Henkelman RM, Bruneau BG	Tbx5-dependent rheostatic control of cardiac gene expression and morphogenesis.	Dev. Biol.	297:2:566-86	2006	16870172		Alessandro D Mori, Yonghong Zhu, Ilyas Vahora, Brian Nieman, Kazuko Koshiba-Takeuchi, Lorinda Davidson, Anne Pizard, J G Seidman, Christine E Seidman, X Josette Chen, R Mark Henkelman, Benoit G Bruneau	Alessandro D Mori	Benoit G Bruneau	The Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.	NA
Delgado-Olguín P, Takeuchi JK, Bruneau BG	Chromatin modification and remodeling in heart development.	ScientificWorldJournal	6:1851-61	2006	17205192		Paul Delgado-Olguín, Jun K Takeuchi, Benoit G Bruneau	Paul Delgado-Olguín	Benoit G Bruneau	Programmes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON, Canada. pauldemian@gmail.com	NA
Bruneau BG	[Irx5: a transcription factor that regulates the cardiac repolarization gradient].	Med Sci (Paris)	22:3:231-2	2006	16527195		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau		NA
Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, Tong D, Veitch GI, Voronina I, Vukobradovic I, Wood GA, Zhu Y, Zirngibl RA, Aubin JE, Bai D, Bruneau BG, Grynpas M, Henderson JE, Henkelman RM, McKerlie C, Sled JG, Stanford WL, Laird DW, Kidder GM, Adamson SL, Rossant J	A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia.	Development	132:19:4375-86	2005	16155213		Ann M Flenniken, Lucy R Osborne, Nicole Anderson, Nadia Ciliberti, Craig Fleming, Joanne E I Gittens, Xiang-Qun Gong, Lois B Kelsey, Crystal Lounsbury, Luisa Moreno, Brian J Nieman, Katie Peterson, Dawei Qu, Wendi Roscoe, Qing Shao, Dan Tong, Gregory I L Veitch, Irina Voronina, Igor Vukobradovic, Geoffrey A Wood, Yonghong Zhu, Ralph A Zirngibl, Jane E Aubin, Donglin Bai, Benoit G Bruneau, Marc Grynpas, Janet E Henderson, R Mark Henkelman, Colin McKerlie, John G Sled, William L Stanford, Dale W Laird, Gerald M Kidder, S Lee Adamson, Janet Rossant	Ann M Flenniken	Janet Rossant	Centre For Modeling Human Disease, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.	NA
Cheng CW, Chow RL, Lebel M, Sakuma R, Cheung HO, Thanabalasingham V, Zhang X, Bruneau BG, Birch DG, Hui CC, McInnes RR, Cheng SH	The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development.	Dev. Biol.	287:1:48-60	2005	16182275		Chi Wa Cheng, Robert L Chow, Mélanie Lebel, Rui Sakuma, Helen Oi-Lam Cheung, Vijitha Thanabalasingham, Xiaoyun Zhang, Benoit G Bruneau, David G Birch, Chi-chung Hui, Roderick R McInnes, Shuk Han Cheng	Chi Wa Cheng	Shuk Han Cheng	Program in Developmental Biology, The Hospital for Sick Children, and Department of Molecular and Medical Genetics, University of Toronto, Toronto, Ontario, Canada M5G 1X8.	NA
Frey BJ, Mohammad N, Morris QD, Zhang W, Robinson MD, Mnaimneh S, Chang R, Pan Q, Sat E, Rossant J, Bruneau BG, Aubin JE, Blencowe BJ, Hughes TR	Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs.	Nat. Genet.	37:9:991-6	2005	16127451		Brendan J Frey, Naveed Mohammad, Quaid D Morris, Wen Zhang, Mark D Robinson, Sanie Mnaimneh, Richard Chang, Qun Pan, Eric Sat, Janet Rossant, Benoit G Bruneau, Jane E Aubin, Benjamin J Blencowe, Timothy R Hughes	Brendan J Frey	Timothy R Hughes	Electrical and Computer Engineering, University of Toronto, 10 King's College Rd., Toronto, Ontario M5S 3G4, Canada. frey@psi.toronto.edu	NA
Bruneau BG	Developmental biology: tiny brakes for a growing heart.	Nature	436:7048:181-2	2005	16015310		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau		NA
Pizard A, Burgon PG, Paul DL, Bruneau BG, Seidman CE, Seidman JG	Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.	Mol. Cell. Biol.	25:12:5073-83	2005	15923624		Anne Pizard, Patrick G Burgon, David L Paul, Benoit G Bruneau, Christine E Seidman, J G Seidman	Anne Pizard	J G Seidman	Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA.	NA
Zhou YQ, Zhu Y, Bishop J, Davidson L, Henkelman RM, Bruneau BG, Foster FS	Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome.	Am. J. Physiol. Heart Circ. Physiol.	289:3:H992-H1001	2005	15849237		Yu-Qing Zhou, Yonghong Zhu, Jonathan Bishop, Lorinda Davidson, R Mark Henkelman, Benoit G Bruneau, F Stuart Foster	Yu-Qing Zhou	F Stuart Foster	Mouse Imaging Centre, Hospital for Sick Children, 555 University Ave., Toronto, ON, Canada M5G 1X8. yqzhou@sickkids.ca	NA
Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG	Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development.	Development	132:10:2463-74	2005	15843409		Jun K Takeuchi, Maria Mileikovskaia, Kazuko Koshiba-Takeuchi, Analeah B Heidt, Alessandro D Mori, Eric P Arruda, Marina Gertsenstein, Romain Georges, Lorinda Davidson, Rong Mo, Chi-Chung Hui, R Mark Henkelman, Mona Nemer, Brian L Black, Andras Nagy, Benoit G Bruneau	Jun K Takeuchi	Benoit G Bruneau	Cardiovascular Research, The Hospital for Sick Children, Toronto, ON, M5G 1X8, Canada.	NA
Barron MR, Belaguli NS, Zhang SX, Trinh M, Iyer D, Merlo X, Lough JW, Parmacek MS, Bruneau BG, Schwartz RJ	Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes.	J. Biol. Chem.	280:12:11816-28	2005	15591049		Matthew R Barron, Narasimhaswamy S Belaguli, Shu Xiang Zhang, Mimi Trinh, Dinaker Iyer, Xanthi Merlo, John W Lough, Michael S Parmacek, Benoit G Bruneau, Robert J Schwartz	Matthew R Barron	Robert J Schwartz	Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.	NHLBI NIH HHS; P01-HL49953
Zhang W, Morris QD, Chang R, Shai O, Bakowski MA, Mitsakakis N, Mohammad N, Robinson MD, Zirngibl R, Somogyi E, Laurin N, Eftekharpour E, Sat E, Grigull J, Pan Q, Peng WT, Krogan N, Greenblatt J, Fehlings M, van der Kooy D, Aubin J, Bruneau BG, Rossant J, Blencowe BJ, Frey BJ, Hughes TR	The functional landscape of mouse gene expression.	J. Biol.	3:5:21	2004	15588312		Wen Zhang, Quaid D Morris, Richard Chang, Ofer Shai, Malina A Bakowski, Nicholas Mitsakakis, Naveed Mohammad, Mark D Robinson, Ralph Zirngibl, Eszter Somogyi, Nancy Laurin, Eftekhar Eftekharpour, Eric Sat, Jörg Grigull, Qun Pan, Wen-Tao Peng, Nevan Krogan, Jack Greenblatt, Michael Fehlings, Derek van der Kooy, Jane Aubin, Benoit G Bruneau, Janet Rossant, Benjamin J Blencowe, Brendan J Frey, Timothy R Hughes	Wen Zhang	Timothy R Hughes	Banting and Best Department of Medical Research, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada. wendy.zhang@utoronto.ca	NA
Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG	Baf60c is essential for function of BAF chromatin remodelling complexes in heart development.	Nature	432:7013:107-12	2004	15525990		Heiko Lickert, Jun K Takeuchi, Ingo Von Both, Johnathon R Walls, Fionnuala McAuliffe, S Lee Adamson, R Mark Henkelman, Jeffrey L Wrana, Janet Rossant, Benoit G Bruneau	Heiko Lickert	Benoit G Bruneau	Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario M5G 1X5, Canada.	NA
McPherson JP, Tamblyn L, Elia A, Migon E, Shehabeldin A, Matysiak-Zablocki E, Lemmers B, Salmena L, Hakem A, Fish J, Kassam F, Squire J, Bruneau BG, Hande MP, Hakem R	Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity.	EMBO J.	23:18:3677-88	2004	15343267		John Peter McPherson, Laura Tamblyn, Andrew Elia, Eva Migon, Amro Shehabeldin, Elzbieta Matysiak-Zablocki, Bénédicte Lemmers, Leonardo Salmena, Anne Hakem, Jason Fish, Farah Kassam, Jeremy Squire, Benoit G Bruneau, M Prakash Hande, Razqallah Hakem	John Peter McPherson	Razqallah Hakem	Division of Cellular & Molecular Biology, Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, Toronto, Ontario, Canada.	NA
Moskowitz IP, Pizard A, Patel VV, Bruneau BG, Kim JB, Kupershmidt S, Roden D, Berul CI, Seidman CE, Seidman JG	The T-Box transcription factor Tbx5 is required for the patterning and maturation of the murine cardiac conduction system.	Development	131:16:4107-16	2004	15289437		Ivan P G Moskowitz, Anne Pizard, Vickas V Patel, Benoit G Bruneau, Jae B Kim, Sabina Kupershmidt, Dan Roden, Charles I Berul, Christine E Seidman, Jonathan G Seidman	Ivan P G Moskowitz	Jonathan G Seidman	Department of Genetics, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA 02115, USA.	NA
Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, Lindsay EA, Baldini A	Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract.	Development	131:13:3217-27	2004	15175244		Huansheng Xu, Masae Morishima, John N Wylie, Robert J Schwartz, Benoit G Bruneau, Elizabeth A Lindsay, Antonio Baldini	Huansheng Xu	Antonio Baldini	Program in Cardiovascular Sciences, Baylor College of Medicine, Houston, TX 77030, USA.	NHLBI NIH HHS; HL67155
Mori AD, Bruneau BG	TBX5 mutations and congenital heart disease: Holt-Oram syndrome revealed.	Curr. Opin. Cardiol.	19:3:211-5	2004	15096952		Alessandro D Mori, Benoit G Bruneau	Alessandro D Mori	Benoit G Bruneau	Program in Cardiovascular Research, Hospital for Sick Children, University of Toronto, Toronto, Canada.	NA
Lebel M, Agarwal P, Cheng CW, Kabir MG, Chan TY, Thanabalasingham V, Zhang X, Cohen DR, Husain M, Cheng SH, Bruneau BG, Hui CC	The Iroquois homeobox gene Irx2 is not essential for normal development of the heart and midbrain-hindbrain boundary in mice.	Mol. Cell. Biol.	23:22:8216-25	2003	14585979		Mélanie Lebel, Pooja Agarwal, Chi Wa Cheng, M Golam Kabir, Toby Y Chan, Vijitha Thanabalasingham, Xiaoyun Zhang, Dana R Cohen, Mansoor Husain, Shuk Han Cheng, Benoit G Bruneau, Chi-Chung Hui	Mélanie Lebel	Chi-Chung Hui	Program in Developmental Biology, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.	NA
Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, Lai D, McDonald LP, Niederreither K, Dolle P, Bruneau BG, Zorn AM, Harvey RP	Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart.	Dev. Biol.	262:2:206-24	2003	14550786		Fiona A Stennard, Mauro W Costa, David A Elliott, Scott Rankin, Saskia J P Haast, Donna Lai, Lachlan P A McDonald, Karen Niederreither, Pascal Dolle, Benoit G Bruneau, Aaron M Zorn, Richard P Harvey	Fiona A Stennard	Richard P Harvey	Victor Chang Cardiac Research Institute, 384 Victoria Street, Darlinghurst, 2010, Sydney, Australia.	NICHD NIH HHS; R01 HD042572
Rallis C, Bruneau BG, Del Buono J, Seidman CE, Seidman JG, Nissim S, Tabin CJ, Logan MP	Tbx5 is required for forelimb bud formation and continued outgrowth.	Development	130:12:2741-51	2003	12736217		Charalampos Rallis, Benoit G Bruneau, Jo Del Buono, Christine E Seidman, J G Seidman, Sahar Nissim, Clifford J Tabin, Malcolm P O Logan	Charalampos Rallis	Malcolm P O Logan	Division of Developmental Biology, National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.	NHLBI NIH HHS; P50 HL61036
Bruneau BG	The developing heart and congenital heart defects: a make or break situation.	Clin. Genet.	63:4:252-61	2003	12702154		B G Bruneau	B G Bruneau	B G Bruneau	Program in Cardiovascular Research, the Hospital for Sick Children, Department of Molecular and Medical Genetics, University of Toronto, ON, Canada. bbruneau@sickkids.ca	NA
Agarwal P, Wylie JN, Galceran J, Arkhitko O, Li C, Deng C, Grosschedl R, Bruneau BG	Tbx5 is essential for forelimb bud initiation following patterning of the limb field in the mouse embryo.	Development	130:3:623-33	2003	12490567		Pooja Agarwal, John N Wylie, Juan Galceran, Oksana Arkhitko, Cuiling Li, Chuxia Deng, Rudolf Grosschedl, Benoit G Bruneau	Pooja Agarwal	Benoit G Bruneau	Programmes in Cardiovascular Research and Developmental Biology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.	NA
Bruneau BG	Transcriptional regulation of vertebrate cardiac morphogenesis.	Circ. Res.	90:5:509-19	2002	11909814		Benoit G Bruneau	Benoit G Bruneau	Benoit G Bruneau	Division of Cardiovascular Research and Programme in Developmental Biology, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8. bbruneau@sickkids.ca.	NA
Bruneau BG, Nemer G, Schmitt JP, Charron F, Robitaille L, Caron S, Conner DA, Gessler M, Nemer M, Seidman CE, Seidman JG	A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.	Cell	106:6:709-21	2001	11572777		B G Bruneau, G Nemer, J P Schmitt, F Charron, L Robitaille, S Caron, D A Conner, M Gessler, M Nemer, C E Seidman, J G Seidman	B G Bruneau	J G Seidman	Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.	NCRR NIH HHS; S10 RR14792
Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG	Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression.	Mol. Cell. Biol.	21:5:1730-6	2001	11238910		B G Bruneau, Z Z Bao, D Fatkin, J Xavier-Neto, D Georgakopoulos, C T Maguire, C I Berul, D A Kass, M L Kuroski-de Bold, A J de Bold, D A Conner, N Rosenthal, C L Cepko, C E Seidman, J G Seidman	B G Bruneau	J G Seidman	Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.	NA
Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE	Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand.	Dev. Biol.	217:2:266-77	2000	10625552		B G Bruneau, Z Z Bao, M Tanaka, J J Schott, S Izumo, C L Cepko, J G Seidman, C E Seidman	B G Bruneau	C E Seidman	Department of Genetics, Harvard Medical School, Boston, Massachusetts, 02115, USA.	NA
Bruneau BG, Logan M, Davis N, Levi T, Tabin CJ, Seidman JG, Seidman CE	Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.	Dev. Biol.	211:1:100-8	1999	10373308		B G Bruneau, M Logan, N Davis, T Levi, C J Tabin, J G Seidman, C E Seidman	B G Bruneau	C E Seidman	Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts, 02115, USA.	NA
Ogawa T, Vatta M, Bruneau BG, de Bold AJ	Characterization of natriuretic peptide production by adult heart atria.	Am. J. Physiol.	276:6 Pt 2:H1977-86	1999	10362678		T Ogawa, M Vatta, B G Bruneau, A J de Bold	T Ogawa	A J de Bold	Cardiac Cell and Molecular Biology Laboratory, University of Ottawa Heart Institute at the Ottawa Hospital, Ottawa, Ontario, Canada K1Y 4W7.	NA
Bao ZZ, Bruneau BG, Seidman JG, Seidman CE, Cepko CL	Regulation of chamber-specific gene expression in the developing heart by Irx4.	Science	283:5405:1161-4	1999	10024241		Z Z Bao, B G Bruneau, J G Seidman, C E Seidman, C L Cepko	Z Z Bao	C L Cepko	Howard Hughes Medical Institute and Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.	NA
Bruneau BG, Piazza LA, de Bold AJ	BNP gene expression is specifically modulated by stretch and ET-1 in a new model of isolated rat atria.	Am. J. Physiol.	273:6 Pt 2:H2678-86	1997	9435604		B G Bruneau, L A Piazza, A J de Bold	B G Bruneau	A J de Bold	University of Ottawa Heart Institute, Ottawa Civic Hospital, Ontario, Canada.	NA
Ogawa T, Bruneau BG, Yokota N, de Bold ML, de Bold AJ	Tissue-specific regulation of renal and cardiac atrial natriuretic factor gene expression in deoxycorticosterone acetate-salt rats.	Hypertension	30:6:1342-7	1997	9403551		T Ogawa, B G Bruneau, N Yokota, M L de Bold, A J de Bold	T Ogawa	A J de Bold	University of Ottawa Heart Institute at the Ottawa Civic Hospital, Ontario, Canada.	NA
Bamshad M, Lin RC, Law DJ, Watkins WC, Krakowiak PA, Moore ME, Franceschini P, Lala R, Holmes LB, Gebuhr TC, Bruneau BG, Schinzel A, Seidman JG, Seidman CE, Jorde LB	Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome.	Nat. Genet.	16:3:311-5	1997	9207801		M Bamshad, R C Lin, D J Law, W C Watkins, P A Krakowiak, M E Moore, P Franceschini, R Lala, L B Holmes, T C Gebuhr, B G Bruneau, A Schinzel, J G Seidman, C E Seidman, L B Jorde	M Bamshad	L B Jorde	Department of Pediatrics, University of Utah Health Sciences Center, Salt Lake City 84112, USA.	PHS HHS; M01-00064
Ogawa T, Linz W, Stevenson M, Bruneau BG, Kuroski de Bold ML, Chen JH, Eid H, Schölkens BA, de Bold AJ	Evidence for load-dependent and load-independent determinants of cardiac natriuretic peptide production.	Circulation	93:11:2059-67	1996	8640983		T Ogawa, W Linz, M Stevenson, B G Bruneau, M L Kuroski de Bold, J H Chen, H Eid, B A Schölkens, A J de Bold	T Ogawa	A J de Bold	University of Ottawa Heart Institute, Ottawa Civic Hospital, Ontario, Canada.	NA
Bruneau BG, Piazza LA, de Bold AJ	Alpha 1-adrenergic stimulation of isolated rat atria results in discoordinate increases in natriuretic peptide secretion and gene expression and enhances Egr-1 and c-Myc expression.	Endocrinology	137:1:137-43	1996	8536605		B G Bruneau, L A Piazza, A J de Bold	B G Bruneau	A J de Bold	University of Ottawa Heart Institute Research Center, Ottawa Civic Hospital, Ontario, Canada.	NA
Yokota N, Bruneau BG, Fernandez BE, de Bold ML, Piazza LA, Eid H, de Bold AJ	Dissociation of cardiac hypertrophy, myosin heavy chain isoform expression, and natriuretic peptide production in DOCA-salt rats.	Am. J. Hypertens.	8:3:301-10	1995	7540847		N Yokota, B G Bruneau, B E Fernandez, M L de Bold, L A Piazza, H Eid, A J de Bold	N Yokota	A J de Bold	University of Ottawa Heart Institute Research Centre, Ottawa Civic Hospital, Ontario, Canada.	NA
Yokota N, Bruneau BG, Kuroski de Bold ML, de Bold AJ	Atrial natriuretic factor significantly contributes to the mineralocorticoid escape phenomenon. Evidence for a guanylate cyclase-mediated pathway.	J. Clin. Invest.	94:5:1938-46	1994	7962539		N Yokota, B G Bruneau, M L Kuroski de Bold, A J de Bold	N Yokota	A J de Bold	University of Ottawa Heart Institute, Ottawa Civic Hospital, Ontario, Canada.	NA
Bruneau BG, de Bold AJ	Selective changes in natriuretic peptide and early response gene expression in isolated rat atria following stimulation by stretch or endothelin-1.	Cardiovasc. Res.	28:10:1519-25	1994	8001040		B G Bruneau, A J de Bold	B G Bruneau	A J de Bold	University of Ottawa Heart Institute, Ottawa Civic Hospital, Ontario, Canada.	NA
Klemm RW, Norton JP, Cole RA, Li CS, Park SH, Crane MM, Li L, Jin D, Boye-Doe A, Liu TY, Shibata Y, Lu H, Rapoport TA, Farese RV, Blackstone C, Guo Y, Mak HY	A conserved role for atlastin GTPases in regulating lipid droplet size.	Cell Rep	3:5:1465-75	2013	23684613		Robin W Klemm, Justin P Norton, Ronald A Cole, Chen S Li, Seong H Park, Matthew M Crane, Liying Li, Diana Jin, Alexandra Boye-Doe, Tina Y Liu, Yoko Shibata, Hang Lu, Tom A Rapoport, Robert V Farese, Craig Blackstone, Yi Guo, Ho Yi Mak	Robin W Klemm	Ho Yi Mak	Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.	NA
Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED	Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice.	J. Neurosci.	33:12:5352-61	2013	23516300		Anthony J Filiano, Lauren Herl Martens, Allen H Young, Brian A Warmus, Ping Zhou, Grisell Diaz-Ramirez, Jian Jiao, Zhijun Zhang, Eric J Huang, Fen-Biao Gao, Robert V Farese, Erik D Roberson	Anthony J Filiano	Erik D Roberson	Center for Neurodegeneration and Experimental Therapeutics, Departments of Neurology and Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.	NINDS NIH HHS; R01 NS075487
Camus G, Herker E, Modi AA, Haas JT, Ramage HR, Farese RV, Ott M	Diacylglycerol acyltransferase-1 localizes hepatitis C virus NS5A protein to lipid droplets and enhances NS5A interaction with the viral capsid core.	J. Biol. Chem.	288:14:9915-23	2013	23420847		Gregory Camus, Eva Herker, Ankit A Modi, Joel T Haas, Holly R Ramage, Robert V Farese, Melanie Ott	Gregory Camus	Melanie Ott	Gladstone Institute of Virology and Immunology, Leibniz Institute for Experimental Virology, Hamburg 20251, Germany.	NIAID NIH HHS; R056 AI069090
Wilfling F, Wang H, Haas JT, Krahmer N, Gould TJ, Uchida A, Cheng JX, Graham M, Christiano R, Fröhlich F, Liu X, Buhman KK, Coleman RA, Bewersdorf J, Farese RV, Walther TC	Triacylglycerol synthesis enzymes mediate lipid droplet growth by relocalizing from the ER to lipid droplets.	Dev. Cell	24:4:384-99	2013	23415954		Florian Wilfling, Huajin Wang, Joel T Haas, Natalie Krahmer, Travis J Gould, Aki Uchida, Ji-Xin Cheng, Morven Graham, Romain Christiano, Florian Fröhlich, Xinran Liu, Kimberly K Buhman, Rosalind A Coleman, Joerg Bewersdorf, Robert V Farese, Tobias C Walther	Florian Wilfling	Tobias C Walther	Department of Cell Biology, Yale School of Medicine, New Haven, CT 06510, USA.	NIGMS NIH HHS; R01 GM099844
Nguyen AD, Nguyen TA, Cenik B, Yu G, Herz J, Walther TC, Davidson WS, Farese RV	Secreted progranulin is a homodimer and is not a component of high density lipoproteins (HDL).	J. Biol. Chem.	288:12:8627-35	2013	23364791		Andrew D Nguyen, Thi A Nguyen, Basar Cenik, Gang Yu, Joachim Herz, Tobias C Walther, W Sean Davidson, Robert V Farese	Andrew D Nguyen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NCRR NIH HHS; RR18928
Krahmer N, Hilger M, Kory N, Wilfling F, Stoehr G, Mann M, Farese RV, Walther TC	Protein correlation profiles identify lipid droplet proteins with high confidence.	Mol. Cell Proteomics	12:5:1115-26	2013	23319140		Natalie Krahmer, Maximiliane Hilger, Nora Kory, Florian Wilfling, Gabriele Stoehr, Matthias Mann, Robert V Farese, Tobias C Walther	Natalie Krahmer	Tobias C Walther	‡Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520;	NA
Haas JT, Winter HS, Lim E, Kirby A, Blumenstiel B, DeFelice M, Gabriel S, Jalas C, Branski D, Grueter CA, Toporovski MS, Walther TC, Daly MJ, Farese RV	DGAT1 mutation is linked to a congenital diarrheal disorder.	J. Clin. Invest.	122:12:4680-4	2012	23114594		Joel T Haas, Harland S Winter, Elaine Lim, Andrew Kirby, Brendan Blumenstiel, Matthew DeFelice, Stacey Gabriel, Chaim Jalas, David Branski, Carrie A Grueter, Mauro S Toporovski, Tobias C Walther, Mark J Daly, Robert V Farese	Joel T Haas	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NCI NIH HHS; CO6 RR018928
Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD	Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models.	Nat. Genet.	44:12:1302-9	2012	23104007		Maria Armakola, Matthew J Higgins, Matthew D Figley, Sami J Barmada, Emily A Scarborough, Zamia Diaz, Xiaodong Fang, James Shorter, Nevan J Krogan, Steven Finkbeiner, Robert V Farese, Aaron D Gitler	Maria Armakola	Aaron D Gitler	Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.	NCRR NIH HHS; RR18928
Eichmann TO, Kumari M, Haas JT, Farese RV, Zimmermann R, Lass A, Zechner R	Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.	J. Biol. Chem.	287:49:41446-57	2012	23066022		Thomas O Eichmann, Manju Kumari, Joel T Haas, Robert V Farese, Robert Zimmermann, Achim Lass, Rudolf Zechner	Thomas O Eichmann	Rudolf Zechner	Institute of Molecular Biosciences, University of Graz, 8010 Graz, Austria.	NA
Almeida S, Zhang Z, Coppola G, Mao W, Futai K, Karydas A, Geschwind MD, Tartaglia MC, Gao F, Gianni D, Sena-Esteves M, Geschwind DH, Miller BL, Farese RV, Gao FB	Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects.	Cell Rep	2:4:789-98	2012	23063362		Sandra Almeida, Zhijun Zhang, Giovanni Coppola, Wenjie Mao, Kensuke Futai, Anna Karydas, Michael D Geschwind, M Carmela Tartaglia, Fuying Gao, Davide Gianni, Miguel Sena-Esteves, Daniel H Geschwind, Bruce L Miller, Robert V Farese, Fen-Biao Gao	Sandra Almeida	Fen-Biao Gao	Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA.	NINDS NIH HHS; R01 NS057553
Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL	The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier).	Alzheimers Dement	9:2:189-98	2013	23062850		Adam L Boxer, Michael Gold, Edward Huey, William T Hu, Howard Rosen, Joel Kramer, Fen-Biao Gao, Edward A Burton, Tiffany Chow, Aimee Kao, Blair R Leavitt, Bruce Lamb, Megan Grether, David Knopman, Nigel J Cairns, Ian R Mackenzie, Laura Mitic, Erik D Roberson, Daniel Van Kammen, Marc Cantillon, Kathleen Zahs, George Jackson, Stephen Salloway, John Morris, Gary Tong, Howard Feldman, Howard Fillit, Susan Dickinson, Zaven S Khachaturian, Margaret Sutherland, Susan Abushakra, Joseph Lewcock, Robert Farese, Robert O Kenet, Frank Laferla, Steve Perrin, Steve Whitaker, Lawrence Honig, Marsel M Mesulam, Brad Boeve, Murray Grossman, Bruce L Miller, Jeffrey L Cummings	Adam L Boxer	Jeffrey L Cummings	Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA. aboxer@memory.ucsf.edu	NIA NIH HHS; R01 AG038791
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV	Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury.	J. Clin. Invest.	122:11:3955-9	2012	23041626		Lauren Herl Martens, Jiasheng Zhang, Sami J Barmada, Ping Zhou, Sherry Kamiya, Binggui Sun, Sang-Won Min, Li Gan, Steven Finkbeiner, Eric J Huang, Robert V Farese	Lauren Herl Martens	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NCRR NIH HHS; RR18928
Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J	Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development.	Alzheimers Dement	9:2:176-88	2013	23043900		Adam L Boxer, Michael Gold, Edward Huey, Fen-Biao Gao, Edward A Burton, Tiffany Chow, Aimee Kao, Blair R Leavitt, Bruce Lamb, Megan Grether, David Knopman, Nigel J Cairns, Ian R Mackenzie, Laura Mitic, Erik D Roberson, Daniel Van Kammen, Marc Cantillon, Kathleen Zahs, Stephen Salloway, John Morris, Gary Tong, Howard Feldman, Howard Fillit, Susan Dickinson, Zaven Khachaturian, Margaret Sutherland, Robert Farese, Bruce L Miller, Jeffrey Cummings	Adam L Boxer	Jeffrey Cummings	Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA. aboxer@memory.ucsf.edu	NIA NIH HHS; R01 AG038791
Xu N, Zhang SO, Cole RA, McKinney SA, Guo F, Haas JT, Bobba S, Farese RV, Mak HY	The FATP1-DGAT2 complex facilitates lipid droplet expansion at the ER-lipid droplet interface.	J. Cell Biol.	198:5:895-911	2012	22927462		Ningyi Xu, Shaobing O Zhang, Ronald A Cole, Sean A McKinney, Fengli Guo, Joel T Haas, Sudheer Bobba, Robert V Farese, Ho Yi Mak	Ningyi Xu	Ho Yi Mak	Stowers Institute for Medical Research, Kansas City, MO 64110, USA.	NIDDK NIH HHS; R01 2R56DK56084
Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB	Hepatic insulin signaling is required for obesity-dependent expression of SREBP-1c mRNA but not for feeding-dependent expression.	Cell Metab.	15:6:873-84	2012	22682225		Joel T Haas, Ji Miao, Dipanjan Chanda, Yanning Wang, Enpeng Zhao, Mary E Haas, Matthew Hirschey, B Vaitheesvaran, Robert V Farese, Irwin J Kurland, Mark Graham, Rosanne Crooke, Fabienne Foufelle, Sudha B Biddinger	Joel T Haas	Sudha B Biddinger	Department of Biochemistry and Biophysics, University of California-San Francisco, and Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL109650
Farese RV, Zechner R, Newgard CB, Walther TC	The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.	Cell Metab.	15:5:570-3	2012	22560209		Robert V Farese, Rudolf Zechner, Christopher B Newgard, Tobias C Walther	Robert V Farese	Tobias C Walther	Gladstone Institute of Cardiovascular Disease, Department of Medicine, University of California, San Francisco, CA 94158, USA. bfarese@gladstone.ucsf.edu	NIGMS NIH HHS; R01 GM097194
Walther TC, Farese RV	Lipid droplets and cellular lipid metabolism.	Annu. Rev. Biochem.	81:687-714	2012	22524315		Tobias C Walther, Robert V Farese	Tobias C Walther	Robert V Farese	Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut 06520, USA. tobias.walther@yale.edu	NIGMS NIH HHS; R01 GM097194
Zhang J, Kelley KL, Marshall SM, Davis MA, Wilson MD, Sawyer JK, Farese RV, Brown JM, Rudel LL	Tissue-specific knockouts of ACAT2 reveal that intestinal depletion is sufficient to prevent diet-induced cholesterol accumulation in the liver and blood.	J. Lipid Res.	53:6:1144-52	2012	22460046		Jun Zhang, Kathryn L Kelley, Stephanie M Marshall, Matthew A Davis, Martha D Wilson, Janet K Sawyer, Robert V Farese, J Mark Brown, Lawrence L Rudel	Jun Zhang	Lawrence L Rudel	Section on Lipid Sciences, Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.	NHLBI NIH HHS; R01-HL51710
Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV	Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice.	Aging (Albany NY)	4:1:13-27	2012	22291164		Ryan S Streeper, Carrie A Grueter, Nathan Salomonis, Sylvaine Cases, Malin C Levin, Suneil K Koliwad, Ping Zhou, Mattew D Hirschey, Eric Verdin, Robert V Farese	Ryan S Streeper	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NIDDK NIH HHS; R01-DK056084
Tschöp MH, Speakman JR, Arch JR, Auwerx J, Brüning JC, Chan L, Eckel RH, Farese RV, Galgani JE, Hambly C, Herman MA, Horvath TL, Kahn BB, Kozma SC, Maratos-Flier E, Müller TD, Münzberg H, Pfluger PT, Plum L, Reitman ML, Rahmouni K, Shulman GI, Thomas G, Kahn CR, Ravussin E	A guide to analysis of mouse energy metabolism.	Nat. Methods	9:1:57-63	2012	22205519		Matthias H Tschöp, John R Speakman, Jonathan R S Arch, Johan Auwerx, Jens C Brüning, Lawrence Chan, Robert H Eckel, Robert V Farese, Jose E Galgani, Catherine Hambly, Mark A Herman, Tamas L Horvath, Barbara B Kahn, Sara C Kozma, Eleftheria Maratos-Flier, Timo D Müller, Heike Münzberg, Paul T Pfluger, Leona Plum, Marc L Reitman, Kamal Rahmouni, Gerald I Shulman, George Thomas, C Ronald Kahn, Eric Ravussin	Matthias H Tschöp	Eric Ravussin	Institute for Diabetes and Obesity, Helmholz Centre Munich, Department of Medicine, Technical University of Munich, Munich, Germany.	NIDDK NIH HHS; R37 DK043051
Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV, Kahn CR, Verdin E	SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.	Mol. Cell	44:2:177-90	2011	21856199		Matthew D Hirschey, Tadahiro Shimazu, Enxuan Jing, Carrie A Grueter, Amy M Collins, Bradley Aouizerat, Alena Stančáková, Eric Goetzman, Maggie M Lam, Bjoern Schwer, Robert D Stevens, Michael J Muehlbauer, Sanjay Kakar, Nathan M Bass, Johanna Kuusisto, Markku Laakso, Frederick W Alt, Christopher B Newgard, Robert V Farese, C Ronald Kahn, Eric Verdin	Matthew D Hirschey	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	Howard Hughes Medical Institute; 
Harris C, Herker E, Farese RV, Ott M	Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis.	J. Biol. Chem.	286:49:42615-25	2011	21984835		Charles Harris, Eva Herker, Robert V Farese, Melanie Ott	Charles Harris	Melanie Ott	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94158, USA.	NIAID NIH HHS; R56 AI085056
Krahmer N, Guo Y, Wilfling F, Hilger M, Lingrell S, Heger K, Newman HW, Schmidt-Supprian M, Vance DE, Mann M, Farese RV, Walther TC	Phosphatidylcholine synthesis for lipid droplet expansion is mediated by localized activation of CTP:phosphocholine cytidylyltransferase.	Cell Metab.	14:4:504-15	2011	21982710		Natalie Krahmer, Yi Guo, Florian Wilfling, Maximiliane Hilger, Susanne Lingrell, Klaus Heger, Heather W Newman, Marc Schmidt-Supprian, Dennis E Vance, Matthias Mann, Robert V Farese, Tobias C Walther	Natalie Krahmer	Tobias C Walther	Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06520, USA.	Canadian Institutes of Health Research; 
Rosen EY, Wexler EM, Versano R, Coppola G, Gao F, Winden KD, Oldham MC, Martens LH, Zhou P, Farese RV, Geschwind DH	Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling.	Neuron	71:6:1030-42	2011	21943601		Ezra Y Rosen, Eric M Wexler, Revital Versano, Giovanni Coppola, Fuying Gao, Kellen D Winden, Michael C Oldham, Lauren Herl Martens, Ping Zhou, Robert V Farese, Daniel H Geschwind	Ezra Y Rosen	Daniel H Geschwind	Interdepartmental Program for Neuroscience, University of California Los Angeles, Los Angeles, CA 90095, USA.	NIMH NIH HHS; T32 MH073526-01A1
Monetti M, Levin MC, Watt MJ, Hubbard BK, Newgard C, Farese RV, Hevener AL, Farese RV	Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity.	Proc. Natl. Acad. Sci. U.S.A.	108:34:E523; author reply E524	2011	21807991		Mara Monetti, Malin C Levin, Matthew J Watt, Brian K Hubbard, Christopher Newgard, Robert V Farese, Andrea L Hevener, Robert V Farese	Mara Monetti	Robert V Farese		NA
Cenik B, Sephton CF, Dewey CM, Xian X, Wei S, Yu K, Niu W, Coppola G, Coughlin SE, Lee SE, Dries DR, Almeida S, Geschwind DH, Gao FB, Miller BL, Farese RV, Posner BA, Yu G, Herz J	Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia.	J. Biol. Chem.	286:18:16101-8	2011	21454553		Basar Cenik, Chantelle F Sephton, Colleen M Dewey, Xunde Xian, Shuguang Wei, Kimberley Yu, Wenze Niu, Giovanni Coppola, Sarah E Coughlin, Suzee E Lee, Daniel R Dries, Sandra Almeida, Daniel H Geschwind, Fen-Biao Gao, Bruce L Miller, Robert V Farese, Bruce A Posner, Gang Yu, Joachim Herz	Basar Cenik	Joachim Herz	Department of Neuroscience, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9111, USA.	NHLBI NIH HHS; R37 HL063762-13
Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV, Kenyon C	A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells.	Proc. Natl. Acad. Sci. U.S.A.	108:11:4441-6	2011	21368173		Aimee W Kao, Robin J Eisenhut, Lauren Herl Martens, Ayumi Nakamura, Anne Huang, Josh A Bagley, Ping Zhou, Alberto de Luis, Lukas J Neukomm, Juan Cabello, Robert V Farese, Cynthia Kenyon	Aimee W Kao	Cynthia Kenyon	Departments of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA.	NIA NIH HHS; R37 AG011816-19
Harris CA, Haas JT, Streeper RS, Stone SJ, Kumari M, Yang K, Han X, Brownell N, Gross RW, Zechner R, Farese RV	DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes.	J. Lipid Res.	52:4:657-67	2011	21317108		Charles A Harris, Joel T Haas, Ryan S Streeper, Scot J Stone, Manju Kumari, Kui Yang, Xianlin Han, Nicholas Brownell, Richard W Gross, Rudolf Zechner, Robert V Farese	Charles A Harris	Robert V Farese	Gladstone Institute for Cardiovascular Disease, Department of Medicine, University of California, San Francisco, CA 94158, USA. charris@gladstone.ucsf.edu	NIDDK NIH HHS; R01-DK-056084
Bewersdorf J, Farese RV, Walther TC	A new way to look at fat.	Nat. Methods	8:2:132-3	2011	21278725		Joerg Bewersdorf, Robert V Farese, Tobias C Walther	Joerg Bewersdorf	Tobias C Walther		NA
Herker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV, Ott M	Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1.	Nat. Med.	16:11:1295-8	2010	20935628		Eva Herker, Charles Harris, Céline Hernandez, Arnaud Carpentier, Katrin Kaehlcke, Arielle R Rosenberg, Robert V Farese, Melanie Ott	Eva Herker	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, USA.	NIAID NIH HHS; R03 AI069090
Jiao J, Herl LD, Farese RV, Gao FB	MicroRNA-29b regulates the expression level of human progranulin, a secreted glycoprotein implicated in frontotemporal dementia.	PLoS ONE	5:5:e10551	2010	20479936		Jian Jiao, Lauren D Herl, Robert V Farese, Fen-Biao Gao	Jian Jiao	Fen-Biao Gao	Gladstone Institute of Neurological Disease, Department of Neurology, University of California San Francisco, San Francisco, California, United States of America.	NINDS NIH HHS; NS066586
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV, Alt FW, Kahn CR, Verdin E	SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.	Nature	464:7285:121-5	2010	20203611		Matthew D Hirschey, Tadahiro Shimazu, Eric Goetzman, Enxuan Jing, Bjoern Schwer, David B Lombard, Carrie A Grueter, Charles Harris, Sudha Biddinger, Olga R Ilkayeva, Robert D Stevens, Yu Li, Asish K Saha, Neil B Ruderman, James R Bain, Christopher B Newgard, Robert V Farese, Frederick W Alt, C Ronald Kahn, Eric Verdin	Matthew D Hirschey	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.	Howard Hughes Medical Institute; 
Koliwad SK, Streeper RS, Monetti M, Cornelissen I, Chan L, Terayama K, Naylor S, Rao M, Hubbard B, Farese RV	DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation.	J. Clin. Invest.	120:3:756-67	2010	20124729		Suneil K Koliwad, Ryan S Streeper, Mara Monetti, Ivo Cornelissen, Liana Chan, Koji Terayama, Stephen Naylor, Meghana Rao, Brian Hubbard, Robert V Farese	Suneil K Koliwad	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. skoliwad@gladstone.ucsf.edu	NIDDK NIH HHS; DK08174-01
Farese RV, Walther TC	Lipid droplets finally get a little R-E-S-P-E-C-T.	Cell	139:5:855-60	2009	19945371		Robert V Farese, Tobias C Walther	Robert V Farese	Tobias C Walther	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. bfarese@gladstone.ucsf.edu	NIDDK NIH HHS; R01 DK056084-09
Krahmer N, Guo Y, Farese RV, Walther TC	SnapShot: Lipid Droplets.	Cell	139:5:1024-1024.e1	2009	19945384		Natalie Krahmer, Yi Guo, Robert V Farese, Tobias C Walther	Natalie Krahmer	Tobias C Walther	Max Planck Institute of Biochemistry, Martinsried 82152, Germany.	NA
Villanueva CJ, Monetti M, Shih M, Zhou P, Watkins SM, Bhanot S, Farese RV	Specific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids.	Hepatology	50:2:434-42	2009	19472314		Claudio J Villanueva, Mara Monetti, Michelle Shih, Ping Zhou, Steve M Watkins, Sanjay Bhanot, Robert V Farese	Claudio J Villanueva	Robert V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA.	NIDDK NIH HHS; R01-DK056084
Koliwad SK, Kuo T, Shipp LE, Gray NE, Backhed F, So AY, Farese RV, Wang JC	Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.	J. Biol. Chem.	284:38:25593-601	2009	19628874		Suneil K Koliwad, Taiyi Kuo, Lauren E Shipp, Nora E Gray, Fredrik Backhed, Alex Yick-Lun So, Robert V Farese, Jen-Chywan Wang	Suneil K Koliwad	Jen-Chywan Wang	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94143, USA.	NA
Guo Y, Cordes KR, Farese RV, Walther TC	Lipid droplets at a glance.	J. Cell. Sci.	122:Pt 6:749-52	2009	19261844		Yi Guo, Kimberly R Cordes, Robert V Farese, Tobias C Walther	Yi Guo	Tobias C Walther	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA. yguo@gladstone.ucsf.edu	NIDDK NIH HHS; R21 DK078254
Yen CL, Cheong ML, Grueter C, Zhou P, Moriwaki J, Wong JS, Hubbard B, Marmor S, Farese RV	Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding.	Nat. Med.	15:4:442-6	2009	19287392		Chi-Liang Eric Yen, Mei-Leng Cheong, Carrie Grueter, Ping Zhou, Junya Moriwaki, Jinny S Wong, Brian Hubbard, Stephen Marmor, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California, USA.	NIDDK NIH HHS; R01 DK056084-01A1
Stone SJ, Levin MC, Zhou P, Han J, Walther TC, Farese RV	The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria.	J. Biol. Chem.	284:8:5352-61	2009	19049983		Scot J Stone, Malin C Levin, Ping Zhou, Jiayi Han, Tobias C Walther, Robert V Farese	Scot J Stone	Robert V Farese	Department of Biochemistry, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5E5, Canada.	NCI NIH HHS; CO6RR018928
Shih MY, Kane MA, Zhou P, Yen CL, Streeper RS, Napoli JL, Farese RV	Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin.	J. Biol. Chem.	284:7:4292-9	2009	19028692		Michelle Y S Shih, Maureen A Kane, Ping Zhou, C L Eric Yen, Ryan S Streeper, Joseph L Napoli, Robert V Farese	Michelle Y S Shih	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.	NIDDK NIH HHS; DK36870
Walther TC, Farese RV	The life of lipid droplets.	Biochim. Biophys. Acta	1791:6:459-66	2009	19041421		Tobias C Walther, Robert V Farese	Tobias C Walther	Robert V Farese	Organelle Architecture and Dynamics, Max Planck Institute of Biochemistry, Martinsried, Germany. twalther@biochem.mpg.de	NIDDK NIH HHS; R21-DK78254
Yen CL, Stone SJ, Koliwad S, Harris C, Farese RV	Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis.	J. Lipid Res.	49:11:2283-301	2008	18757836		Chi-Liang Eric Yen, Scot J Stone, Suneil Koliwad, Charles Harris, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Department of Nutritional Sciences, University of Wisconsin, Madison, WI 53706, USA.	NIDDK NIH HHS; R01 DK056084-01A1
Minehira K, Young SG, Villanueva CJ, Yetukuri L, Oresic M, Hellerstein MK, Farese RV, Horton JD, Preitner F, Thorens B, Tappy L	Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice.	J. Lipid Res.	49:9:2038-44	2008	18515909		Kaori Minehira, Stephen G Young, Claudio J Villanueva, Laxman Yetukuri, Matej Oresic, Mark K Hellerstein, Robert V Farese, Jay D Horton, Frederic Preitner, Bernard Thorens, Luc Tappy	Kaori Minehira	Luc Tappy	Gladstone Institute of Cardiovascular Disease, University of California-San Francisco, CA 94158, USA. kaori.minehira@unil.ch	NHLBI NIH HHS; R01 HL087228-04
Guo Y, Walther TC, Rao M, Stuurman N, Goshima G, Terayama K, Wong JS, Vale RD, Walter P, Farese RV	Functional genomic screen reveals genes involved in lipid-droplet formation and utilization.	Nature	453:7195:657-61	2008	18408709		Yi Guo, Tobias C Walther, Meghana Rao, Nico Stuurman, Gohta Goshima, Koji Terayama, Jinny S Wong, Ronald D Vale, Peter Walter, Robert V Farese	Yi Guo	Robert V Farese	Department of Biochemistry and Biophysics, University of California, San Francisco, California 94158, USA.	Howard Hughes Medical Institute; 
Levin MC, Monetti M, Watt MJ, Sajan MP, Stevens RD, Bain JR, Newgard CB, Farese RV, Farese RV	Increased lipid accumulation and insulin resistance in transgenic mice expressing DGAT2 in glycolytic (type II) muscle.	Am. J. Physiol. Endocrinol. Metab.	293:6:E1772-81	2007	17940217		Malin C Levin, Mara Monetti, Matthew J Watt, Mini P Sajan, Robert D Stevens, James R Bain, Christopher B Newgard, Robert V Farese, Robert V Farese	Malin C Levin	Robert V Farese	Gladstone Institute of Cardiovascular Disease, 1650 Owens St., San Francisco, CA 94158, USA.	NIDDK NIH HHS; R01 DK065969
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, Guarente LP, Farese RV, Weissman S, Verdin E, Schwer B	Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation.	Mol. Cell. Biol.	27:24:8807-14	2007	17923681		David B Lombard, Frederick W Alt, Hwei-Ling Cheng, Jakob Bunkenborg, Ryan S Streeper, Raul Mostoslavsky, Jennifer Kim, George Yancopoulos, David Valenzuela, Andrew Murphy, Yinhua Yang, Yaohui Chen, Matthew D Hirschey, Roderick T Bronson, Marcia Haigis, Leonard P Guarente, Robert V Farese, Sherman Weissman, Eric Verdin, Bjoern Schwer	David B Lombard	Bjoern Schwer	Howard Hughes Medical Institute, The Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.	NCRR NIH HHS; 1C06RR18928
Chan LC, Peters W, Xu Y, Chun J, Farese RV, Cases S	LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA).	J. Leukoc. Biol.	82:5:1193-200	2007	17709403		Liana C Chan, Wendy Peters, Yan Xu, Jerold Chun, Robert V Farese, Sylvaine Cases	Liana C Chan	Sylvaine Cases	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NCI NIH HHS; R21 CA109291
Monetti M, Levin MC, Watt MJ, Sajan MP, Marmor S, Hubbard BK, Stevens RD, Bain JR, Newgard CB, Farese RV, Hevener AL, Farese RV	Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.	Cell Metab.	6:1:69-78	2007	17618857		Mara Monetti, Malin C Levin, Matthew J Watt, Mini P Sajan, Stephen Marmor, Brian K Hubbard, Robert D Stevens, James R Bain, Christopher B Newgard, Robert V Farese, Andrea L Hevener, Robert V Farese	Mara Monetti	Robert V Farese	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NIDDK NIH HHS; R01-DK065599
Stone SJ, Levin MC, Farese RV	Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2.	J. Biol. Chem.	281:52:40273-82	2006	17035227		Scot J Stone, Malin C Levin, Robert V Farese	Scot J Stone	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. sstone@gladstone.ucsf.edu	NIDDK NIH HHS; 5R01-DK065599
Feldman BJ, Streeper RS, Farese RV, Yamamoto KR	Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects.	Proc. Natl. Acad. Sci. U.S.A.	103:42:15675-80	2006	17030820		Brian J Feldman, Ryan S Streeper, Robert V Farese, Keith R Yamamoto	Brian J Feldman	Keith R Yamamoto	Department of Pediatrics, University of California, San Francisco, CA 94143, USA.	NIDDK NIH HHS; DK73697
Farese RV	The nine lives of ACAT inhibitors.	Arterioscler. Thromb. Vasc. Biol.	26:8:1684-6	2006	16857957		Robert V Farese	Robert V Farese	Robert V Farese		NA
Millar JS, Stone SJ, Tietge UJ, Tow B, Billheimer JT, Wong JS, Hamilton RL, Farese RV, Rader DJ	Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production.	J. Lipid Res.	47:10:2297-305	2006	16877777		John S Millar, Scot J Stone, Uwe J F Tietge, Bryan Tow, Jeffrey T Billheimer, Jinny S Wong, Robert L Hamilton, Robert V Farese, Daniel J Rader	John S Millar	Daniel J Rader	Department of Pharmacology, University of Pennsylvania, Philadelphia, PA, USA. jsmillar@mail.med.upenn.edu	NHLBI NIH HHS; HL-10365
Rudel LL, Farese RV	ACAT inhibition and the progression of coronary atherosclerosis.	N. Engl. J. Med.	354:24:2616-7; author reply 2616-7	2006	16775245		Lawrence L Rudel, Robert V Farese	Lawrence L Rudel	Robert V Farese		NA
Yen CL, Farese RV	Fat breakdown: a function for CGI-58 (ABHD5) provides a new piece of the puzzle.	Cell Metab.	3:5:305-7	2006	16679288		Chi-Liang Eric Yen, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NA
Streeper RS, Koliwad SK, Villanueva CJ, Farese RV	Effects of DGAT1 deficiency on energy and glucose metabolism are independent of adiponectin.	Am. J. Physiol. Endocrinol. Metab.	291:2:E388-94	2006	16595853		Ryan S Streeper, Suneil K Koliwad, Claudio J Villanueva, Robert V Farese	Ryan S Streeper	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NIDDK NIH HHS; R01-DK-56084
Yen CL, Brown CH, Monetti M, Farese RV	A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters.	J. Lipid Res.	46:11:2388-97	2005	16106050		Chi-Liang Eric Yen, Charles H Brown, Mara Monetti, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. eyen@gladstone.ucsf.edu	NIDDK NIH HHS; R01 DK056084
Yen CL, Monetti M, Burri BJ, Farese RV	The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters.	J. Lipid Res.	46:7:1502-11	2005	15834126		Chi-Liang Eric Yen, Mara Monetti, Betty J Burri, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA. eyen@gladstone.ucsf.edu	NIDDK NIH HHS; DK-56084
Chen HC, Farese RV	Inhibition of triglyceride synthesis as a treatment strategy for obesity: lessons from DGAT1-deficient mice.	Arterioscler. Thromb. Vasc. Biol.	25:3:482-6	2005	15569818		Hubert C Chen, Robert V Farese	Hubert C Chen	Robert V Farese	Department of Medical Sciences, Amgen Inc, Thousand Oaks, USA.	NA
Repa JJ, Buhman KK, Farese RV, Dietschy JM, Turley SD	ACAT2 deficiency limits cholesterol absorption in the cholesterol-fed mouse: impact on hepatic cholesterol homeostasis.	Hepatology	40:5:1088-97	2004	15486928		Joyce J Repa, Kimberly K Buhman, Robert V Farese, John M Dietschy, Stephen D Turley	Joyce J Repa	Stephen D Turley	Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390-8887, USA.	NHLBI NIH HHS; R37-HL 09610
Lee RG, Kelley KL, Sawyer JK, Farese RV, Parks JS, Rudel LL	Plasma cholesteryl esters provided by lecithin:cholesterol acyltransferase and acyl-coenzyme a:cholesterol acyltransferase 2 have opposite atherosclerotic potential.	Circ. Res.	95:10:998-1004	2004	15486318		Richard G Lee, Kathryn L Kelley, Janet K Sawyer, Robert V Farese, John S Parks, Lawrence L Rudel	Richard G Lee	Lawrence L Rudel	Arteriosclerosis Research Program, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.	NHLBI NIH HHS; HL-49373
Chen HC, Rao M, Sajan MP, Standaert M, Kanoh Y, Miura A, Farese RV, Farese RV	Role of adipocyte-derived factors in enhancing insulin signaling in skeletal muscle and white adipose tissue of mice lacking Acyl CoA:diacylglycerol acyltransferase 1.	Diabetes	53:6:1445-51	2004	15161747		Hubert C Chen, Meghana Rao, Mini P Sajan, Mary Standaert, Yoshinori Kanoh, Atsushi Miura, Robert V Farese, Robert V Farese	Hubert C Chen	Robert V Farese	James A. Haley Veterans Hospital, ACOS-151, 13000 Bruce B. Downs Blvd., Tampa, FL 33612, USA.	NIDDK NIH HHS; R01-DK56804
Cases S, Zhou P, Shillingford JM, Wiseman BS, Fish JD, Angle CS, Hennighausen L, Werb Z, Farese RV	Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues.	Development	131:13:3047-55	2004	15163627		Sylvaine Cases, Ping Zhou, Jonathan M Shillingford, Bryony S Wiseman, Jo Dee Fish, Christina S Angle, Lothar Hennighausen, Zena Werb, Robert V Farese	Sylvaine Cases	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-1900, USA.	NIEHS NIH HHS; U01 ES012801-02
Standaert ML, Sajan MP, Miura A, Kanoh Y, Chen HC, Farese RV, Farese RV	Insulin-induced activation of atypical protein kinase C, but not protein kinase B, is maintained in diabetic (ob/ob and Goto-Kakazaki) liver. Contrasting insulin signaling patterns in liver versus muscle define phenotypes of type 2 diabetic and high fat-induced insulin-resistant states.	J. Biol. Chem.	279:24:24929-34	2004	15069067		Mary L Standaert, Mini P Sajan, Atsushi Miura, Yoshinori Kanoh, Hubert C Chen, Robert V Farese, Robert V Farese	Mary L Standaert	Robert V Farese	Research Service, James A. Haley Veterans Medical Center and Department of Internal Medicine, University of South Florida College of Medicine, Tampa, Florida 33612, USA.	NIDDK NIH HHS; R01-DK-56804
Stone SJ, Myers HM, Watkins SM, Brown BE, Feingold KR, Elias PM, Farese RV	Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.	J. Biol. Chem.	279:12:11767-76	2004	14668353		Scot J Stone, Heather M Myers, Steven M Watkins, Barbara E Brown, Kenneth R Feingold, Peter M Elias, Robert V Farese	Scot J Stone	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-1900, USA.	NIDDK NIH HHS; DK56084
Gohil K, Schock BC, Chakraborty AA, Terasawa Y, Raber J, Farese RV, Packer L, Cross CE, Traber MG	Gene expression profile of oxidant stress and neurodegeneration in transgenic mice deficient in alpha-tocopherol transfer protein.	Free Radic. Biol. Med.	35:11:1343-54	2003	14642382		Kishorchandra Gohil, Bettina C Schock, Abhishek A Chakraborty, Yuko Terasawa, Jacob Raber, Robert V Farese, Lester Packer, Carroll E Cross, Maret G Traber	Kishorchandra Gohil	Maret G Traber	Center for Comparative Respiratory and Medicine, Department of Internal Medicine, University of California, Davis, CA 95616, USA. kgohil@ucdavis.edu	NIEHS NIH HHS; ES11528-02
Chen HC, Jensen DR, Myers HM, Eckel RH, Farese RV	Obesity resistance and enhanced glucose metabolism in mice transplanted with white adipose tissue lacking acyl CoA:diacylglycerol acyltransferase 1.	J. Clin. Invest.	111:11:1715-22	2003	12782674		Hubert C Chen, Dalan R Jensen, Heather M Myers, Robert H Eckel, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NIDDK NIH HHS; R01-DK56084
Listenberger LL, Han X, Lewis SE, Cases S, Farese RV, Ory DS, Schaffer JE	Triglyceride accumulation protects against fatty acid-induced lipotoxicity.	Proc. Natl. Acad. Sci. U.S.A.	100:6:3077-82	2003	12629214		Laura L Listenberger, Xianlin Han, Sarah E Lewis, Sylvaine Cases, Robert V Farese, Daniel S Ory, Jean E Schaffer	Laura L Listenberger	Jean E Schaffer	Center for Cardiovascular Research, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO 63110-1010, USA.	NHLBI NIH HHS; T32 HL 07275
Yen CL, Farese RV	MGAT2, a monoacylglycerol acyltransferase expressed in the small intestine.	J. Biol. Chem.	278:20:18532-7	2003	12621063		Chi-Liang Eric Yen, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-1900, USA.	NIDDK NIH HHS; DK56084
Willner EL, Tow B, Buhman KK, Wilson M, Sanan DA, Rudel LL, Farese RV	Deficiency of acyl CoA:cholesterol acyltransferase 2 prevents atherosclerosis in apolipoprotein E-deficient mice.	Proc. Natl. Acad. Sci. U.S.A.	100:3:1262-7	2003	12538880		Emily L Willner, Bryan Tow, Kimberly K Buhman, Martha Wilson, David A Sanan, Lawrence L Rudel, Robert V Farese	Emily L Willner	Robert V Farese	Gladstone Institute of Cardiovascular Disease, P. O. Box 419100, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; R01-HL57170
Chen HC, Stone SJ, Zhou P, Buhman KK, Farese RV	Dissociation of obesity and impaired glucose disposal in mice overexpressing acyl coenzyme a:diacylglycerol acyltransferase 1 in white adipose tissue.	Diabetes	51:11:3189-95	2002	12401709		Hubert C Chen, Scot J Stone, Ping Zhou, Kimberly K Buhman, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NIDDK NIH HHS; R01-DK56804
Chen HC, Ladha Z, Smith SJ, Farese RV	Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1.	Am. J. Physiol. Endocrinol. Metab.	284:1:E213-8	2003	12388146		Hubert C Chen, Zuleika Ladha, Steven J Smith, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94143, USA.	NIDDK NIH HHS; R01-DK-56084
Chen HC, Ladha Z, Farese RV	Deficiency of acyl coenzyme a:diacylglycerol acyltransferase 1 increases leptin sensitivity in murine obesity models.	Endocrinology	143:8:2893-8	2002	12130553		Hubert C Chen, Zuleika Ladha, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, University of California-San Francisco, San Francisco, CA 94143, USA.	NIDDK NIH HHS; DK 56804
Ludwig EH, Mahley RW, Palaoglu E, Ozbayrakçi S, Balestra ME, Borecki IB, Innerarity TL, Farese RV	DGAT1 promoter polymorphism associated with alterations in body mass index, high density lipoprotein levels and blood pressure in Turkish women.	Clin. Genet.	62:1:68-73	2002	12123490		Erwin H Ludwig, R W Mahley, E Palaoglu, S Ozbayrakçi, M E Balestra, I B Borecki, T L Innerarity, R V Farese	Erwin H Ludwig	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA, USA. eludwig@xenongenetics.com	NHLBI NIH HHS; HL 47660
Chen HC, Farese RV	Fatty acids, triglycerides, and glucose metabolism: recent insights from knockout mice.	Curr Opin Clin Nutr Metab Care	5:4:359-63	2002	12107369		Hubert C Chen, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NA
Yen CL, Stone SJ, Cases S, Zhou P, Farese RV	Identification of a gene encoding MGAT1, a monoacylglycerol acyltransferase.	Proc. Natl. Acad. Sci. U.S.A.	99:13:8512-7	2002	12077311		Chi-Liang Eric Yen, Scot J Stone, Sylvaine Cases, Ping Zhou, Robert V Farese	Chi-Liang Eric Yen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-1900, USA.	NIDDK NIH HHS; DK56084
Chen HC, Farese RV	Determination of adipocyte size by computer image analysis.	J. Lipid Res.	43:6:986-9	2002	12032175		Hubert C Chen, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, University of California, San Francisco, CA 94141, USA.	NA
Chen HC, Bandyopadhyay G, Sajan MP, Kanoh Y, Standaert M, Farese RV, Farese RV	Activation of the ERK pathway and atypical protein kinase C isoforms in exercise- and aminoimidazole-4-carboxamide-1-beta-D-riboside (AICAR)-stimulated glucose transport.	J. Biol. Chem.	277:26:23554-62	2002	11978788		Hubert C Chen, Gautam Bandyopadhyay, Mini P Sajan, Yoshinori Kanoh, Mary Standaert, Robert V Farese, Robert V Farese	Hubert C Chen	Robert V Farese	James A. Haley Veterans Hospital and the Department of Internal Medicine, University of South Florida College of Medicine, Tampa, Florida 33612, USA.	NIDDK NIH HHS; R01 DK065969
Buhman KK, Smith SJ, Stone SJ, Repa JJ, Wong JS, Knapp FF, Burri BJ, Hamilton RL, Abumrad NA, Farese RV	DGAT1 is not essential for intestinal triacylglycerol absorption or chylomicron synthesis.	J. Biol. Chem.	277:28:25474-9	2002	11959864		Kimberly K Buhman, Steven J Smith, Scot J Stone, Joyce J Repa, Jinny S Wong, F F Knapp, Betty J Burri, Robert L Hamilton, Nada A Abumrad, Robert V Farese	Kimberly K Buhman	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NIDDK NIH HHS; DK56084
Chen HC, Smith SJ, Ladha Z, Jensen DR, Ferreira LD, Pulawa LK, McGuire JG, Pitas RE, Eckel RH, Farese RV	Increased insulin and leptin sensitivity in mice lacking acyl CoA:diacylglycerol acyltransferase 1.	J. Clin. Invest.	109:8:1049-55	2002	11956242		Hubert C Chen, Steven J Smith, Zuleika Ladha, Dalan R Jensen, Luis D Ferreira, Leslie K Pulawa, James G McGuire, Robert E Pitas, Robert H Eckel, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, PO Box 419100, San Francisco, California 94141-9100, USA.	NIDDK NIH HHS; DK-56804
Leonard SW, Terasawa Y, Farese RV, Traber MG	Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.	Am. J. Clin. Nutr.	75:3:555-60	2002	11864863		Scott W Leonard, Yuko Terasawa, Robert V Farese, Maret G Traber	Scott W Leonard	Maret G Traber	Linus Pauling Institute, Oregon State University, Corvallis, USA.	NIEHS NIH HHS; ES00210
Chen HC, Smith SJ, Tow B, Elias PM, Farese RV	Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands.	J. Clin. Invest.	109:2:175-81	2002	11805129		Hubert C Chen, Steven J Smith, Bryan Tow, Peter M Elias, Robert V Farese	Hubert C Chen	Robert V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NIDDK NIH HHS; R01 DK56084
Chen HC, Farese RV	Turning WAT into BAT gets rid of fat.	Nat. Med.	7:10:1102-3	2001	11590426		H C Chen, R V Farese	H C Chen	R V Farese		NA
Raffai RL, Dong LM, Farese RV, Weisgraber KH	Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E.	Proc. Natl. Acad. Sci. U.S.A.	98:20:11587-91	2001	11553788		R L Raffai, L M Dong, R V Farese, K H Weisgraber	R L Raffai	K H Weisgraber	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141, USA.	NINDS NIH HHS; NS35939
Buhman KK, Chen HC, Farese RV	The enzymes of neutral lipid synthesis.	J. Biol. Chem.	276:44:40369-72	2001	11544264		K K Buhman, H C Chen, R V Farese	K K Buhman	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NA
Cases S, Stone SJ, Zhou P, Yen E, Tow B, Lardizabal KD, Voelker T, Farese RV	Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.	J. Biol. Chem.	276:42:38870-6	2001	11481335		S Cases, S J Stone, P Zhou, E Yen, B Tow, K D Lardizabal, T Voelker, R V Farese	S Cases	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94143, USA.	NIDDK NIH HHS; DK56084
Sonda S, Ting LM, Novak S, Kim K, Maher JJ, Farese RV, Ernst JD	Cholesterol esterification by host and parasite is essential for optimal proliferation of Toxoplasma gondii.	J. Biol. Chem.	276:37:34434-40	2001	11457847		S Sonda, L M Ting, S Novak, K Kim, J J Maher, R V Farese, J D Ernst	S Sonda	J D Ernst	Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, California 94143-0868, USA.	NIDDK NIH HHS; DK 26743
Fazio S, Major AS, Swift LL, Gleaves LA, Accad M, Linton MF, Farese RV	Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages.	J. Clin. Invest.	107:2:163-71	2001	11160132		S Fazio, A S Major, L L Swift, L A Gleaves, M Accad, M F Linton, R V Farese	S Fazio	R V Farese	Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, 315 Medical Research Building, Nashville, Tennessee 37232-6300, USA. sergio.fazio@mcmail.vanderbilt.edu	NHLBI NIH HHS; HL-57170
Buhman KF, Accad M, Farese RV	Mammalian acyl-CoA:cholesterol acyltransferases.	Biochim. Biophys. Acta	1529:1-3:142-54	2000	11111084		K F Buhman, M Accad, R V Farese	K F Buhman	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL57170
Terasawa Y, Ladha Z, Leonard SW, Morrow JD, Newland D, Sanan D, Packer L, Traber MG, Farese RV	Increased atherosclerosis in hyperlipidemic mice deficient in alpha -tocopherol transfer protein and vitamin E.	Proc. Natl. Acad. Sci. U.S.A.	97:25:13830-4	2000	11095717		Y Terasawa, Z Ladha, S W Leonard, J D Morrow, D Newland, D Sanan, L Packer, M G Traber, R V Farese	Y Terasawa	R V Farese	Gladstone Institute of Cardiovascular Disease, P. O. Box 419100, San Francisco, CA 94141-9100, USA.	NIDDK NIH HHS; DK48831
Buhman KK, Accad M, Novak S, Choi RS, Wong JS, Hamilton RL, Turley S, Farese RV	Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.	Nat. Med.	6:12:1341-7	2000	11100118		K K Buhman, M Accad, S Novak, R S Choi, J S Wong, R L Hamilton, S Turley, R V Farese	K K Buhman	R V Farese	Gladstone Institute of Cardiovascular Disease, P.O. Box 419100, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL60844
Yamanaka S, Zhang XY, Maeda M, Miura K, Wang S, Farese RV, Iwao H, Innerarity TL	Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway.	EMBO J.	19:20:5533-41	2000	11032820		S Yamanaka, X Y Zhang, M Maeda, K Miura, S Wang, R V Farese, H Iwao, T L Innerarity	S Yamanaka	T L Innerarity	Laboratory of Animal Molecular Technology, Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma 630-0101, Nara, Japan. shinyay@gtc.aist-nara.ac.jp	NA
Chang CC, Sakashita N, Ornvold K, Lee O, Chang ET, Dong R, Lin S, Lee CY, Strom SC, Kashyap R, Fung JJ, Farese RV, Patoiseau JF, Delhon A, Chang TY	Immunological quantitation and localization of ACAT-1 and ACAT-2 in human liver and small intestine.	J. Biol. Chem.	275:36:28083-92	2000	10846185		C C Chang, N Sakashita, K Ornvold, O Lee, E T Chang, R Dong, S Lin, C Y Lee, S C Strom, R Kashyap, J J Fung, R V Farese, J F Patoiseau, A Delhon, T Y Chang	C C Chang	T Y Chang	Department of Biochemistry, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.	NHLBI NIH HHS; HL 60306
Chen HC, Farese RV	DGAT and triglyceride synthesis: a new target for obesity treatment?	Trends Cardiovasc. Med.	10:5:188-92	2000	11282293		H C Chen, R V Farese	H C Chen	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA. hcc1@itsa.ucsf.edu	NHLBI NIH HHS; HL57170
Huang XZ, Wu JF, Ferrando R, Lee JH, Wang YL, Farese RV, Sheppard D	Fatal bilateral chylothorax in mice lacking the integrin alpha9beta1.	Mol. Cell. Biol.	20:14:5208-15	2000	10866676		X Z Huang, J F Wu, R Ferrando, J H Lee, Y L Wang, R V Farese, D Sheppard	X Z Huang	D Sheppard	Lung Biology Center, Center for Occupational and Environmental Health, Cardiovascular Research Institute, San Francisco, California 94143-0854, USA.	NHLBI NIH HHS; HL53949
Farese RV, Cases S, Smith SJ	Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase.	Curr. Opin. Lipidol.	11:3:229-34	2000	10882337		R V Farese, S Cases, S J Smith	R V Farese	S J Smith	Gladstone Institutes of Cardiovascular Disease, San Francisco, CA 94141-9100, USA. bfarese@gladstone.ucsf.edu	NHLBI NIH HHS; HL57170
Smith SJ, Cases S, Jensen DR, Chen HC, Sande E, Tow B, Sanan DA, Raber J, Eckel RH, Farese RV	Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat.	Nat. Genet.	25:1:87-90	2000	10802663		S J Smith, S Cases, D R Jensen, H C Chen, E Sande, B Tow, D A Sanan, J Raber, R H Eckel, R V Farese	S J Smith	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California, USA.	NA
Accad M, Smith SJ, Newland DL, Sanan DA, King LE, Linton MF, Fazio S, Farese RV	Massive xanthomatosis and altered composition of atherosclerotic lesions in hyperlipidemic mice lacking acyl CoA:cholesterol acyltransferase 1.	J. Clin. Invest.	105:6:711-9	2000	10727439		M Accad, S J Smith, D L Newland, D A Sanan, L E King, M F Linton, S Fazio, R V Farese	M Accad	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL57986
Huang X, Griffiths M, Wu J, Farese RV, Sheppard D	Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice.	Mol. Cell. Biol.	20:3:755-9	2000	10629031		X Huang, M Griffiths, J Wu, R V Farese, D Sheppard	X Huang	D Sheppard	Lung Biology Center, University of California, San Francisco, San Francisco, California 94143-0854, USA.	NHLBI NIH HHS; HL53949
Terasawa Y, Cases SJ, Wong JS, Jamil H, Jothi S, Traber MG, Packer L, Gordon DA, Hamilton RL, Farese RV	Apolipoprotein B-related gene expression and ultrastructural characteristics of lipoprotein secretion in mouse yolk sac during embryonic development.	J. Lipid Res.	40:11:1967-77	1999	10553000		Y Terasawa, S J Cases, J S Wong, H Jamil, S Jothi, M G Traber, L Packer, D A Gordon, R L Hamilton, R V Farese	Y Terasawa	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94110, USA.	NHLBI NIH HHS; HL60844
Chen HC, Farese RV	Steroid hormones: Interactions with membrane-bound receptors.	Curr. Biol.	9:13:R478-81	1999	10395533		H C Chen, R V Farese	H C Chen	R V Farese	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, Department of Medicine, University of California at San Francisco, San Francisco, California 94141-9100, USA. hccl@itsa.ucsf.edu	NA
Herz J, Farese RV	The LDL receptor gene family, apolipoprotein B and cholesterol in embryonic development.	J. Nutr.	129:2S Suppl:473S-475S	1999	10064312		J Herz, R V Farese	J Herz	R V Farese	Department of Molecular Genetics, UT Southwestern, Dallas 75235, USA.	NHLBI NIH HHS; HL20948
Cases S, Smith SJ, Zheng YW, Myers HM, Lear SR, Sande E, Novak S, Collins C, Welch CB, Lusis AJ, Erickson SK, Farese RV	Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis.	Proc. Natl. Acad. Sci. U.S.A.	95:22:13018-23	1998	9789033		S Cases, S J Smith, Y W Zheng, H M Myers, S R Lear, E Sande, S Novak, C Collins, C B Welch, A J Lusis, S K Erickson, R V Farese	S Cases	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94143, USA.	NHLBI NIH HHS; HL57170
Cases S, Novak S, Zheng YW, Myers HM, Lear SR, Sande E, Welch CB, Lusis AJ, Spencer TA, Krause BR, Erickson SK, Farese RV	ACAT-2, a second mammalian acyl-CoA:cholesterol acyltransferase. Its cloning, expression, and characterization.	J. Biol. Chem.	273:41:26755-64	1998	9756919		S Cases, S Novak, Y W Zheng, H M Myers, S R Lear, E Sande, C B Welch, A J Lusis, T A Spencer, B R Krause, S K Erickson, R V Farese	S Cases	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL57170
Accad M, Farese RV	Cholesterol homeostasis: a role for oxysterols.	Curr. Biol.	8:17:R601-4	1998	9742388		M Accad, R V Farese	M Accad	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California at San Francisco 94141-9100, USA.	NA
Kahn ML, Zheng YW, Huang W, Bigornia V, Zeng D, Moff S, Farese RV, Tam C, Coughlin SR	A dual thrombin receptor system for platelet activation.	Nature	394:6694:690-4	1998	9716134		M L Kahn, Y W Zheng, W Huang, V Bigornia, D Zeng, S Moff, R V Farese, C Tam, S R Coughlin	M L Kahn	S R Coughlin	Cardiovascular Research Institute, Department of Medicine, University of California, San Francisco 94143-0130, USA.	NA
Khelef N, Buton X, Beatini N, Wang H, Meiner V, Chang TY, Farese RV, Maxfield FR, Tabas I	Immunolocalization of acyl-coenzyme A:cholesterol O-acyltransferase in macrophages.	J. Biol. Chem.	273:18:11218-24	1998	9556612		N Khelef, X Buton, N Beatini, H Wang, V Meiner, T Y Chang, R V Farese, F R Maxfield, I Tabas	N Khelef	I Tabas	Department of Biochemistry, Cornell University Medical School, New York, New York 10021, USA.	NCRR NIH HHS; S10 RR10506
Farese RV	Acyl CoA:cholesterol acyltransferase genes and knockout mice.	Curr. Opin. Lipidol.	9:2:119-23	1998	9559268		R V Farese	R V Farese	R V Farese	Gladstone Institute of Cardiovascular Disease and Department of Medicine, University of California, San Francisco 94141-9100, USA. bob_farese.gicd@quickmail.ucsf.edu	NHLBI NIH HHS; HL57179
Farese RV, Herz J	Cholesterol metabolism and embryogenesis.	Trends Genet.	14:3:115-20	1998	9540409		R V Farese, J Herz	R V Farese	J Herz	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141, USA. bob_farese@quickmail.ucsf.edu	NA
Meiner VL, Welch CL, Cases S, Myers HM, Sande E, Lusis AJ, Farese RV	Adrenocortical lipid depletion gene (ald) in AKR mice is associated with an acyl-CoA:cholesterol acyltransferase (ACAT) mutation.	J. Biol. Chem.	273:2:1064-9	1998	9422770		V L Meiner, C L Welch, S Cases, H M Myers, E Sande, A J Lusis, R V Farese	V L Meiner	R V Farese	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL42488
Khovidhunkit W, Farese RV	Resolution of propylthiouracil-induced hepatic failure after treatment of thyrotoxicosis.	West. J. Med.	167:5:353-6	1997	9392993		W Khovidhunkit, R V Farese	W Khovidhunkit	R V Farese	Department of Medicine, University of California, San Francisco, USA.	NA
Meiner V, Tam C, Gunn MD, Dong LM, Weisgraber KH, Novak S, Myers HM, Erickson SK, Farese RV	Tissue expression studies on the mouse acyl-CoA: cholesterol acyltransferase gene (Acact): findings supporting the existence of multiple cholesterol esterification enzymes in mice.	J. Lipid Res.	38:9:1928-33	1997	9323603		V Meiner, C Tam, M D Gunn, L M Dong, K H Weisgraber, S Novak, H M Myers, S K Erickson, R V Farese	V Meiner	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL52069
Herz J, Willnow TE, Farese RV	Cholesterol, hedgehog and embryogenesis.	Nat. Genet.	15:2:123-4	1997	9020834		J Herz, T E Willnow, R V Farese	J Herz	R V Farese		NA
Meiner VL, Cases S, Myers HM, Sande ER, Bellosta S, Schambelan M, Pitas RE, McGuire J, Herz J, Farese RV	Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals.	Proc. Natl. Acad. Sci. U.S.A.	93:24:14041-6	1996	8943057		V L Meiner, S Cases, H M Myers, E R Sande, S Bellosta, M Schambelan, R E Pitas, J McGuire, J Herz, R V Farese	V L Meiner	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94110, USA.	NCRR NIH HHS; RR-83
Welch CL, Xia YR, Shechter I, Farese R, Mehrabian M, Mehdizadeh S, Warden CH, Lusis AJ	Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes.	J. Lipid Res.	37:7:1406-21	1996	8827514		C L Welch, Y R Xia, I Shechter, R Farese, M Mehrabian, S Mehdizadeh, C H Warden, A J Lusis	C L Welch	A J Lusis	Department of Pathology, University of California, Los Angeles 90095, USA.	NHLBI NIH HHS; HL48540
Farese RV, Véniant MM, Cham CM, Flynn LM, Pierotti V, Loring JF, Traber M, Ruland S, Stokowski RS, Huszar D, Young SG	Phenotypic analysis of mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.	Proc. Natl. Acad. Sci. U.S.A.	93:13:6393-8	1996	8692825		R V Farese, M M Véniant, C M Cham, L M Flynn, V Pierotti, J F Loring, M Traber, S Ruland, R S Stokowski, D Huszar, S G Young	R V Farese	S G Young	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL47660
Connolly AJ, Ishihara H, Kahn ML, Farese RV, Coughlin SR	Role of the thrombin receptor in development and evidence for a second receptor.	Nature	381:6582:516-9	1996	8632823		A J Connolly, H Ishihara, M L Kahn, R V Farese, S R Coughlin	A J Connolly	S R Coughlin	Cardiovascular Research Institute, University of California, San Francisco, 94143-0524, USA.	NA
Huang XZ, Wu JF, Cass D, Erle DJ, Corry D, Young SG, Farese RV, Sheppard D	Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.	J. Cell Biol.	133:4:921-8	1996	8666675		X Z Huang, J F Wu, D Cass, D J Erle, D Corry, S G Young, R V Farese, D Sheppard	X Z Huang	D Sheppard	Lung Biology Center, University of California, San Francisco 94143, USA.	NHLBI NIH HHS; HL53949
Hirano K, Young SG, Farese RV, Ng J, Sande E, Warburton C, Powell-Braxton LM, Davidson NO	Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48.	J. Biol. Chem.	271:17:9887-90	1996	8626621		K Hirano, S G Young, R V Farese, J Ng, E Sande, C Warburton, L M Powell-Braxton, N O Davidson	K Hirano	N O Davidson	Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA.	NHLBI NIH HHS; HL-38180
Farese RV, Cases S, Ruland SL, Kayden HJ, Wong JS, Young SG, Hamilton RL	A novel function for apolipoprotein B: lipoprotein synthesis in the yolk sac is critical for maternal-fetal lipid transport in mice.	J. Lipid Res.	37:2:347-60	1996	9026532		R V Farese, S Cases, S L Ruland, H J Kayden, J S Wong, S G Young, R L Hamilton	R V Farese	R L Hamilton	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; P01 HL47660
Young SG, Cham CM, Pitas RE, Burri BJ, Connolly A, Flynn L, Pappu AS, Wong JS, Hamilton RL, Farese RV	A genetic model for absent chylomicron formation: mice producing apolipoprotein B in the liver, but not in the intestine.	J. Clin. Invest.	96:6:2932-46	1995	8675665		S G Young, C M Cham, R E Pitas, B J Burri, A Connolly, L Flynn, A S Pappu, J S Wong, R L Hamilton, R V Farese	S G Young	R V Farese	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; P01HL-47660
Purcell-Huynh DA, Farese RV, Johnson DF, Flynn LM, Pierotti V, Newland DL, Linton MF, Sanan DA, Young SG	Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.	J. Clin. Invest.	95:5:2246-57	1995	7738190		D A Purcell-Huynh, R V Farese, D F Johnson, L M Flynn, V Pierotti, D L Newland, M F Linton, D A Sanan, S G Young	D A Purcell-Huynh	S G Young	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL-41633
Farese RV, Ruland SL, Flynn LM, Stokowski RP, Young SG	Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes.	Proc. Natl. Acad. Sci. U.S.A.	92:5:1774-8	1995	7878058		R V Farese, S L Ruland, L M Flynn, R P Stokowski, S G Young	R V Farese	S G Young	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; P01 HL47660
Zysow BR, Pullinger CR, Hennessy LK, Farese RV, Ghassemzadeh M, Kane JP	The apolipoprotein C-II variant apoC-IILys19-->Thr is not associated with dyslipidemia in an affected kindred.	Clin. Genet.	45:6:292-7	1994	7923858		B R Zysow, C R Pullinger, L K Hennessy, R V Farese, M Ghassemzadeh, J P Kane	B R Zysow	J P Kane	Department of Medicine, University of California, San Francisco 94143-0130.	NHLBI NIH HHS; HL45753
Young SG, Farese RV, Pierotti VR, Taylor S, Grass DS, Linton MF	Transgenic mice expressing human apoB100 and apoB48.	Curr. Opin. Lipidol.	5:2:94-101	1994	8044422		S G Young, R V Farese, V R Pierotti, S Taylor, D S Grass, M F Linton	S G Young	M F Linton	Gladstone Institute of Cardiovascular Disease, San Francisco.	PHS HHS; 41633
Linton MF, Farese RV, Young SG	Familial hypobetalipoproteinemia.	J. Lipid Res.	34:4:521-41	1993	8496659		M F Linton, R V Farese, S G Young	M F Linton	S G Young	Gladstone Institute of Cardiovascular Disease, Department of Medicine, University of California, San Francisco 94141-9100.	PHS HHS; 41633
Young SG, Pullinger CR, Zysow BR, Hofmann-Radvani H, Linton MF, Farese RV, Terdiman JF, Snyder SM, Grundy SM, Vega GL	Four new mutations in the apolipoprotein B gene causing hypobetalipoproteinemia, including two different frameshift mutations that yield truncated apolipoprotein B proteins of identical length.	J. Lipid Res.	34:3:501-7	1993	8468533		S G Young, C R Pullinger, B R Zysow, H Hofmann-Radvani, M F Linton, R V Farese, J F Terdiman, S M Snyder, S M Grundy, G L Vega	S G Young	G L Vega	Gladstone Institute for Cardiovascular Disease, San Francisco, CA 94141-9100.	NHLBI NIH HHS; HL41633
Farese RV, Flynn LM, Young SG	Modification of the apolipoprotein B gene in HepG2 cells by gene targeting.	J. Clin. Invest.	90:1:256-61	1992	1321843		R V Farese, L M Flynn, S G Young	R V Farese	S G Young	Gladstone Institute of Cardiovascular Disease, Department of Medicine, University of California, San Francisco 94141-9100.	NIDDK NIH HHS; DK07418
Farese RV, Linton MF, Young SG	Apolipoprotein B gene mutations affecting cholesterol levels.	J. Intern. Med.	231:6:643-52	1992	1619387		R V Farese, M F Linton, S G Young	R V Farese	S G Young	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Medicine, University of California, San Francisco.	NHLBI NIH HHS; HL41633
Farese RV, Garg A, Pierotti VR, Vega GL, Young SG	A truncated species of apolipoprotein B, B-83, associated with hypobetalipoproteinemia.	J. Lipid Res.	33:4:569-77	1992	1527480		R V Farese, A Garg, V R Pierotti, G L Vega, S G Young	R V Farese	S G Young	Gladstone Foundation Laboratories for Cardiovascular Research, University of California, San Francisco 94140-0608.	NCRR NIH HHS; M01-RR-00633
Farese RV, Biglieri EG, Shackleton CH, Irony I, Gomez-Fontes R	Licorice-induced hypermineralocorticoidism.	N. Engl. J. Med.	325:17:1223-7	1991	1922210		R V Farese, E G Biglieri, C H Shackleton, I Irony, R Gomez-Fontes	R V Farese	R Gomez-Fontes	General Clinical Research Center, San Francisco General Hospital Medical Center.	NCRR NIH HHS; RR00083
Farese RV, Yost TJ, Eckel RH	Tissue-specific regulation of lipoprotein lipase activity by insulin/glucose in normal-weight humans.	Metab. Clin. Exp.	40:2:214-6	1991	1988780		R V Farese, T J Yost, R H Eckel	R V Farese	R H Eckel	Division of Endocrinology, University of Colorado Health Sciences Center, Denver 80262.	NCRR NIH HHS; RR-0005
Farese RV, Schambelan M, Hollander H, Stringari S, Jacobson MA	Nephrogenic diabetes insipidus associated with foscarnet treatment of cytomegalovirus retinitis.	Ann. Intern. Med.	112:12:955-6	1990	2160217		R V Farese, M Schambelan, H Hollander, S Stringari, M A Jacobson	R V Farese	M A Jacobson	San Francisco General Hospital, California.	NHLBI NIH HHS; HL-11046
Hainsworth JD, Johnson DH, Farese RV, Macey JW, Vaughn WK, Greco FA	Limited stage small cell lung cancer: analysis of clinical prognostic factors.	South. Med. J.	80:12:1518-22	1987	2827319		J D Hainsworth, D H Johnson, R V Farese, J W Macey, W K Vaughn, F A Greco	J D Hainsworth	F A Greco	Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tenn.	NCI NIH HHS; CA 23909
Farese RV, Farese RV, Sabir MA, Larson RE, Trudeau WL, Barnes D	The mechanism of action of insulin on phospholipid metabolism in rat adipose tissue. Requirement for protein synthesis and a carbohydrate source, and relationship to activation of pyruvate dehydrogenase.	Diabetes	33:7:648-55	1984	6329860		R V Farese, R V Farese, M A Sabir, R E Larson, W L Trudeau, D Barnes	R V Farese	D Barnes		NHLBI NIH HHS; 1-RO1-HL-28290-02
Mahley RW	Shinya Yamanaka, M.D., Ph.D. - 2012 Nobel Prize Laureate: How his dream of a research career provides vision for the next generation of young scientists.	Anadolu Kardiyol Derg	13:3:204-6	2013	23618992		Robert W Mahley	Robert W Mahley	Robert W Mahley	Gladstone Institute of Cardiovascular Disease and Gladstone Institute of Neurological Disease, University of California, San Francisco, California-USA; Departments of Pathology and Medicine, University of California, San Francisco, California-USA. rmahley@gladstone.ucsf.edu.	NA
Mahley RW, Huang Y	Apolipoprotein e sets the stage: response to injury triggers neuropathology.	Neuron	76:5:871-85	2012	23217737		Robert W Mahley, Yadong Huang	Robert W Mahley	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. rmahley@gladstone.ucsf.edu	NIA NIH HHS; R01 AG028793
Mahley RW, Huang Y	Small-molecule structure correctors target abnormal protein structure and function: structure corrector rescue of apolipoprotein E4-associated neuropathology.	J. Med. Chem.	55:21:8997-9008	2012	23013167		Robert W Mahley, Yadong Huang	Robert W Mahley	Yadong Huang	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, California 94158, United States. rmahley@gladstone.ucsf.edu	NIA NIH HHS; P01 AG022074
Naylor MD, Karlawish JH, Arnold SE, Khachaturian AS, Khachaturian ZS, Lee VM, Baumgart M, Banerjee S, Beck C, Blennow K, Brookmeyer R, Brunden KR, Buckwalter KC, Comer M, Covinsky K, Feinberg LF, Frisoni G, Green C, Guimaraes RM, Gwyther LP, Hefti FF, Hutton M, Kawas C, Kent DM, Kuller L, Langa KM, Mahley RW, Maslow K, Masters CL, Meier DE, Neumann PJ, Paul SM, Petersen RC, Sager MA, Sano M, Schenk D, Soares H, Sperling RA, Stahl SM, van Deerlin V, Stern Y, Weir D, Wolk DA, Trojanowski JQ	Advancing Alzheimer's disease diagnosis, treatment, and care: recommendations from the Ware Invitational Summit.	Alzheimers Dement	8:5:445-52	2012	22959699		Mary D Naylor, Jason H Karlawish, Steven E Arnold, Ara S Khachaturian, Zaven S Khachaturian, Virginia M-Y Lee, Matthew Baumgart, Sube Banerjee, Cornelia Beck, Kaj Blennow, Ron Brookmeyer, Kurt R Brunden, Kathleen C Buckwalter, Meryl Comer, Kenneth Covinsky, Lynn Friss Feinberg, Giovanni Frisoni, Colin Green, Renato Maia Guimaraes, Lisa P Gwyther, Franz F Hefti, Michael Hutton, Claudia Kawas, David M Kent, Lewis Kuller, Kenneth M Langa, Robert W Mahley, Katie Maslow, Colin L Masters, Diane E Meier, Peter J Neumann, Steven M Paul, Ronald C Petersen, Mark A Sager, Mary Sano, Dale Schenk, Holly Soares, Reisa A Sperling, Sidney M Stahl, Vivianna van Deerlin, Yaakov Stern, David Weir, David A Wolk, John Q Trojanowski	Mary D Naylor	John Q Trojanowski	Institute on Aging, University of Pennsylvania, Philadelphia, USA. naylor@nursing.upenn.edu	NIA NIH HHS; P30 AG010124
Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikäinen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kähönen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Böhringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimäki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sigurðsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Serrano-Ríos M, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Penninx BW, Boomsma DI, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Peltonen L, Mooser V, Sladek R, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Chasman DI, Johansen CT, Fouchier SW, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Feitosa MF, Orho-Melander M, Melander O, Li X, Li M, Cho YS, Go MJ, Kim YJ, Lee JY, Park T, Kim K, Sim X, Ong RT, Croteau-Chonka DC, Lange LA, Smith JD, Ziegler A, Zhang W, Zee RY, Whitfield JB, Thompson JR, Surakka I, Spector TD, Smit JH, Sinisalo J, Scott J, Saharinen J, Sabatti C, Rose LM, Roberts R, Rieder M, Parker AN, Pare G, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, McArdle W, Masson D, Martin NG, Marroni F, Lucas G, Luben R, Lokki ML, Lettre G, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, König IR, Khaw KT, Kaplan LM, Johansson Å, Janssens AC, Igl W, Hovingh GK, Hengstenberg C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Groop LC, Gonzalez E, Freimer NB, Erdmann J, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, de Faire U, Crawford G, Chen YD, Caulfield MJ, Boekholdt SM, Assimes TL, Quertermous T, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Taylor HA, Gabriel SB, Holm H, Gudnason V, Krauss RM, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Strachan DP, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Kathiresan S	Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.	PLoS Genet.	8:3:e1002607	2012	22479202		Zari Dastani, Marie-France Hivert, Nicholas Timpson, John R B Perry, Xin Yuan, Robert A Scott, Peter Henneman, Iris M Heid, Jorge R Kizer, Leo-Pekka Lyytikäinen, Christian Fuchsberger, Toshiko Tanaka, Andrew P Morris, Kerrin Small, Aaron Isaacs, Marian Beekman, Stefan Coassin, Kurt Lohman, Lu Qi, Stavroula Kanoni, James S Pankow, Hae-Won Uh, Ying Wu, Aurelian Bidulescu, Laura J Rasmussen-Torvik, Celia M T Greenwood, Martin Ladouceur, Jonna Grimsby, Alisa K Manning, Ching-Ti Liu, Jaspal Kooner, Vincent E Mooser, Peter Vollenweider, Karen A Kapur, John Chambers, Nicholas J Wareham, Claudia Langenberg, Rune Frants, Ko Willems-Vandijk, Ben A Oostra, Sara M Willems, Claudia Lamina, Thomas W Winkler, Bruce M Psaty, Russell P Tracy, Jennifer Brody, Ida Chen, Jorma Viikari, Mika Kähönen, Peter P Pramstaller, David M Evans, Beate St Pourcain, Naveed Sattar, Andrew R Wood, Stefania Bandinelli, Olga D Carlson, Josephine M Egan, Stefan Böhringer, Diana van Heemst, Lyudmyla Kedenko, Kati Kristiansson, Marja-Liisa Nuotio, Britt-Marie Loo, Tamara Harris, Melissa Garcia, Alka Kanaya, Margot Haun, Norman Klopp, H-Erich Wichmann, Panos Deloukas, Efi Katsareli, David J Couper, Bruce B Duncan, Margreet Kloppenburg, Linda S Adair, Judith B Borja, James G Wilson, Solomon Musani, Xiuqing Guo, Toby Johnson, Robert Semple, Tanya M Teslovich, Matthew A Allison, Susan Redline, Sarah G Buxbaum, Karen L Mohlke, Ingrid Meulenbelt, Christie M Ballantyne, George V Dedoussis, Frank B Hu, Yongmei Liu, Bernhard Paulweber, Timothy D Spector, P Eline Slagboom, Luigi Ferrucci, Antti Jula, Markus Perola, Olli Raitakari, Jose C Florez, Veikko Salomaa, Johan G Eriksson, Timothy M Frayling, Andrew A Hicks, Terho Lehtimäki, George Davey Smith, David S Siscovick, Florian Kronenberg, Cornelia van Duijn, Ruth J F Loos, Dawn M Waterworth, James B Meigs, Josee Dupuis, J Brent Richards, Benjamin F Voight, Laura J Scott, Valgerdur Steinthorsdottir, Christian Dina, Ryan P 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Uitterlinden, Mark Walker, Richard M Watanabe, Goncalo R Abecasis, Bernhard O Boehm, Harry Campbell, Mark J Daly, Andrew T Hattersley, Oluf Pedersen, Inês Barroso, Leif Groop, Rob Sladek, Unnur Thorsteinsdottir, James F Wilson, Thomas Illig, Philippe Froguel, Cornelia M van Duijn, Kari Stefansson, David Altshuler, Michael Boehnke, Mark I McCarthy, Nicole Soranzo, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Reedik Mägi, Joshua Randall, Paul Elliott, Denis Rybin, Abbas Dehghan, Jouke Jan Hottenga, Kijoung Song, Anuj Goel, Taina Lajunen, Alex Doney, Christine Cavalcanti-Proença, Meena Kumari, Nicholas J Timpson, Carina Zabena, Erik Ingelsson, Ping An, Jeffrey O'Connell, Jian'an Luan, Amanda Elliott, Steven A McCarroll, Rosa Maria Roccasecca, François Pattou, Praveen Sethupathy, Yavuz Ariyurek, Philip Barter, John P Beilby, Yoav Ben-Shlomo, Sven Bergmann, Murielle Bochud, Amélie Bonnefond, Knut Borch-Johnsen, Yvonne Böttcher, Eric Brunner, Suzannah J Bumpstead, Yii-Der Ida Chen, 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Schwarz, Joachim Spranger, Fredrik Karpe, Alan R Shuldiner, Cyrus Cooper, Manuel Serrano-Ríos, Lars Lind, Lyle J Palmer, Frank B Hu, Paul W Franks, Shah Ebrahim, Michael Marmot, W H Linda Kao, Peter Paul Pramstaller, Alan F Wright, Michael Stumvoll, Anders Hamsten, Thomas A Buchanan, Timo T Valle, Jerome I Rotter, Brenda W J H Penninx, Dorret I Boomsma, Antonio Cao, Angelo Scuteri, David Schlessinger, Manuela Uda, Aimo Ruokonen, Marjo-Riitta Jarvelin, Leena Peltonen, Vincent Mooser, Robert Sladek, Kiran Musunuru, Albert V Smith, Andrew C Edmondson, Ioannis M Stylianou, Masahiro Koseki, James P Pirruccello, Daniel I Chasman, Christopher T Johansen, Sigrid W Fouchier, Gina M Peloso, Maja Barbalic, Sally L Ricketts, Joshua C Bis, Mary F Feitosa, Marju Orho-Melander, Olle Melander, Xiaohui Li, Mingyao Li, Yoon Shin Cho, Min Jin Go, Young Jin Kim, Jong-Young Lee, Taesung Park, Kyunga Kim, Xueling Sim, Rick Twee-Hee Ong, Damien C Croteau-Chonka, Leslie A Lange, Joshua D Smith, Andreas Ziegler, Weihua Zhang, Robert Y L Zee, John B Whitfield, John R Thompson, Ida Surakka, Tim D Spector, Johannes H Smit, Juha Sinisalo, James Scott, Juha Saharinen, Chiara Sabatti, Lynda M Rose, Robert Roberts, Mark Rieder, Alex N Parker, Guillaume Pare, Christopher J O'Donnell, Markku S Nieminen, Deborah A Nickerson, Grant W Montgomery, Wendy McArdle, David Masson, Nicholas G Martin, Fabio Marroni, Gavin Lucas, Robert Luben, Marja-Liisa Lokki, Guillaume Lettre, Lenore J Launer, Edward G Lakatta, Reijo Laaksonen, Kirsten O Kyvik, Inke R König, Kay-Tee Khaw, Lee M Kaplan, Åsa Johansson, A Cecile J W Janssens, Wilmar Igl, G Kees Hovingh, Christian Hengstenberg, Aki S Havulinna, Nicholas D Hastie, Tamara B Harris, Talin Haritunians, Alistair S Hall, Leif C Groop, Elena Gonzalez, Nelson B Freimer, Jeanette Erdmann, Kenechi G Ejebe, Angela Döring, Anna F Dominiczak, Serkalem Demissie, Panagiotis Deloukas, Ulf de Faire, Gabriel Crawford, Yii-der I Chen, Mark J Caulfield, S Matthijs Boekholdt, Themistocles L Assimes, Thomas Quertermous, Mark Seielstad, Tien Y Wong, E-Shyong Tai, Alan B Feranil, Christopher W Kuzawa, Herman A Taylor, Stacey B Gabriel, Hilma Holm, Vilmundur Gudnason, Ronald M Krauss, Jose M Ordovas, Patricia B Munroe, Jaspal S Kooner, Alan R Tall, Robert A Hegele, John J P Kastelein, Eric E Schadt, David P Strachan, Muredach P Reilly, Nilesh J Samani, Heribert Schunkert, L Adrienne Cupples, Manjinder S Sandhu, Paul M Ridker, Daniel J Rader, Sekar Kathiresan	Zari Dastani	Sekar Kathiresan	Department of Epidemiology, Biostatistics, and Occupational Health, Jewish General Hospital, Lady Davis Institute, McGill University, Montreal, Canada.	Wellcome Trust; 
Hodoğlugil U, Mahley RW	Turkish population structure and genetic ancestry reveal relatedness among Eurasian populations.	Ann. Hum. Genet.	76:2:128-41	2012	22332727		Uğur Hodoğlugil, Robert W Mahley	Uğur Hodoğlugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL71027
Palmer ND, McDonough CW, Hicks PJ, Roh BH, Wing MR, An SS, Hester JM, Cooke JN, Bostrom MA, Rudock ME, Talbert ME, Lewis JP, Ferrara A, Lu L, Ziegler JT, Sale MM, Divers J, Shriner D, Adeyemo A, Rotimi CN, Ng MC, Langefeld CD, Freedman BI, Bowden DW, Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Boström KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Mägi R, Randall J, Johnson T, Elliott P, Rybin D, Henneman P, Dehghan A, Hottenga JJ, Song K, Goel A, Egan JM, Lajunen T, Doney A, Kanoni S, Cavalcanti-Proença C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hicks AA, Hillman DR, Hingorani AD, Hui J, Hung J, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Oostra BA, Orrù M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Tönjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Lind L, Palmer LJ, Franks PW, Ebrahim S, Marmot M, Kao WH, Pramstaller PP, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Ferrucci L, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Sladek R	A genome-wide association search for type 2 diabetes genes in African Americans.	PLoS ONE	7:1:e29202	2012	22238593		Nicholette D Palmer, Caitrin W McDonough, Pamela J Hicks, Bong H Roh, Maria R Wing, S Sandy An, Jessica M Hester, Jessica N Cooke, Meredith A Bostrom, Megan E Rudock, Matthew E Talbert, Joshua P Lewis, Assiamira Ferrara, Lingyi Lu, Julie T Ziegler, Michele M Sale, Jasmin Divers, Daniel Shriner, Adebowale Adeyemo, Charles N Rotimi, Maggie C Y Ng, Carl D Langefeld, Barry I Freedman, Donald W Bowden, Benjamin F Voight, Laura J Scott, Valgerdur Steinthorsdottir, Andrew P Morris, Christian Dina, Ryan P Welch, Eleftheria Zeggini, Cornelia Huth, Yurii S Aulchenko, Gudmar Thorleifsson, Laura J McCulloch, Teresa Ferreira, Harald Grallert, Najaf Amin, Guanming Wu, Cristen J Willer, Soumya Raychaudhuri, Steve A McCarroll, Claudia Langenberg, Oliver M Hofmann, Josée Dupuis, Lu Qi, Ayellet V Segrè, Mandy van Hoek, Pau Navarro, Kristin Ardlie, Beverley Balkau, Rafn Benediktsson, Amanda J Bennett, Roza Blagieva, Eric Boerwinkle, Lori L Bonnycastle, Kristina Bengtsson Boström, Bert Bravenboer, Suzannah Bumpstead, Noël P Burtt, Guillaume Charpentier, Peter S Chines, Marilyn Cornelis, David J Couper, Gabe Crawford, Alex S F Doney, Katherine S Elliott, Amanda L Elliott, Michael R Erdos, Caroline S Fox, Christopher S Franklin, Martha Ganser, Christian Gieger, Niels Grarup, Todd Green, Simon Griffin, Christopher J Groves, Candace Guiducci, Samy Hadjadj, Neelam Hassanali, Christian Herder, Bo Isomaa, Anne U Jackson, Paul R V Johnson, Torben Jørgensen, Wen H L Kao, Norman Klopp, Augustine Kong, Peter Kraft, Johanna Kuusisto, Torsten Lauritzen, Man Li, Aloysius Lieverse, Cecilia M Lindgren, Valeriya Lyssenko, Michel Marre, Thomas Meitinger, Kristian Midthjell, Mario A Morken, Narisu Narisu, Peter Nilsson, Katharine R Owen, Felicity Payne, John R B Perry, Ann-Kristin Petersen, Carl Platou, Christine Proença, Inga Prokopenko, Wolfgang Rathmann, N William Rayner, Neil R Robertson, Ghislain Rocheleau, Michael Roden, Michael J Sampson, Richa Saxena, Beverley M Shields, Peter Shrader, Gunnar Sigurdsson, Thomas Sparsø, Klaus Strassburger, Heather M Stringham, Qi Sun, Amy J Swift, Barbara Thorand, Jean Tichet, Tiinamaija Tuomi, Rob M van Dam, Timon W van Haeften, Thijs van Herpt, Jana V van Vliet-Ostaptchouk, G Bragi Walters, Michael N Weedon, Cisca Wijmenga, Jacqueline Witteman, Richard N Bergman, Stephane Cauchi, Francis S Collins, Anna L Gloyn, Ulf Gyllensten, Torben Hansen, Winston A Hide, Graham A Hitman, Albert Hofman, David J Hunter, Kristian Hveem, Markku Laakso, Karen L Mohlke, Andrew D Morris, Colin N A Palmer, Peter P Pramstaller, Igor Rudan, Eric Sijbrands, Lincoln D Stein, Jaakko Tuomilehto, Andre Uitterlinden, Mark Walker, Nicholas J Wareham, Richard M Watanabe, Goncalo R Abecasis, Bernhard O Boehm, Harry Campbell, Mark J Daly, Andrew T Hattersley, Frank B Hu, James B Meigs, James S Pankow, Oluf Pedersen, H-Erich Wichmann, Inês Barroso, Jose C Florez, Timothy M Frayling, Leif Groop, Rob Sladek, Unnur Thorsteinsdottir, James F Wilson, Thomas Illig, Philippe Froguel, Cornelia M van Duijn, Kari Stefansson, David Altshuler, Michael Boehnke, Mark I McCarthy, Nicole Soranzo, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Reedik Mägi, Joshua Randall, Toby Johnson, Paul Elliott, Denis Rybin, Peter Henneman, Abbas Dehghan, Jouke Jan Hottenga, Kijoung Song, Anuj Goel, Josephine M Egan, Taina Lajunen, Alex Doney, Stavroula Kanoni, Christine Cavalcanti-Proença, Meena Kumari, Nicholas J Timpson, Carina Zabena, Erik Ingelsson, Ping An, Jeffrey O'Connell, Jian'an Luan, Amanda Elliott, Steven A McCarroll, Rosa Maria Roccasecca, François Pattou, Praveen Sethupathy, Yavuz Ariyurek, Philip Barter, John P Beilby, Yoav Ben-Shlomo, Sven Bergmann, Murielle Bochud, Amélie Bonnefond, Knut Borch-Johnsen, Yvonne Böttcher, Eric Brunner, Suzannah J Bumpstead, Yii-Der Ida Chen, Peter Chines, Robert Clarke, Lachlan J M Coin, Matthew N Cooper, Laura Crisponi, Ian N M Day, Eco J C de Geus, Jerome Delplanque, Annette C Fedson, Antje Fischer-Rosinsky, Nita G Forouhi, Rune Frants, Maria Grazia Franzosi, Pilar Galan, Mark O Goodarzi, Jürgen Graessler, Scott Grundy, Rhian Gwilliam, Göran Hallmans, Naomi Hammond, Xijing Han, Anna-Liisa Hartikainen, Caroline Hayward, Simon C Heath, Serge Hercberg, Andrew A Hicks, David R Hillman, Aroon D Hingorani, Jennie Hui, Joe Hung, Antti Jula, Marika Kaakinen, Jaakko Kaprio, Y Antero Kesaniemi, Mika Kivimaki, Beatrice Knight, Seppo Koskinen, Peter Kovacs, Kirsten Ohm Kyvik, G Mark Lathrop, Debbie A Lawlor, Olivier Le Bacquer, Cécile Lecoeur, Yun Li, Robert Mahley, Massimo Mangino, Alisa K Manning, María Teresa Martínez-Larrad, Jarred B McAteer, Ruth McPherson, Christa Meisinger, David Melzer, David Meyre, Braxton D Mitchell, Sutapa Mukherjee, Silvia Naitza, Matthew J Neville, Ben A Oostra, Marco Orrù, Ruth Pakyz, Giuseppe Paolisso, Cristian Pattaro, Daniel Pearson, John F Peden, Nancy L Pedersen, Markus Perola, Andreas F H Pfeiffer, Irene Pichler, Ozren Polasek, Danielle Posthuma, Simon C Potter, Anneli Pouta, Michael A Province, Bruce M Psaty, Nigel W Rayner, Kenneth Rice, Samuli Ripatti, Fernando Rivadeneira, Olov Rolandsson, Annelli Sandbaek, Manjinder Sandhu, Serena Sanna, Avan Aihie Sayer, Paul Scheet, Udo Seedorf, Stephen J Sharp, Beverley Shields, Eric J G Sijbrands, Angela Silveira, Laila Simpson, Andrew Singleton, Nicholas L Smith, Ulla Sovio, Amy Swift, Holly Syddall, Ann-Christine Syvänen, Toshiko Tanaka, Anke Tönjes, André G Uitterlinden, Ko Willems van Dijk, Dhiraj Varma, Sophie Visvikis-Siest, Veronique Vitart, Nicole Vogelzangs, Gérard Waeber, Peter J Wagner, Andrew Walley, Kim L Ward, Hugh Watkins, Sarah H Wild, Gonneke Willemsen, Jaqueline C M Witteman, John W G Yarnell, Diana Zelenika, Björn Zethelius, Guangju Zhai, Jing Hua Zhao, M Carola Zillikens, Ingrid B Borecki, Ruth J F Loos, Pierre Meneton, Patrik K E Magnusson, David M Nathan, Gordon H Williams, Kaisa Silander, Veikko Salomaa, George Davey Smith, Stefan R Bornstein, Peter Schwarz, Joachim Spranger, Fredrik Karpe, Alan R Shuldiner, Cyrus Cooper, George V Dedoussis, Manuel Serrano-Ríos, Lars Lind, Lyle J Palmer, Paul W Franks, Shah Ebrahim, Michael Marmot, W H Linda Kao, Peter Paul Pramstaller, Alan F Wright, Michael Stumvoll, Anders Hamsten, Thomas A Buchanan, Timo T Valle, Jerome I Rotter, David S Siscovick, Brenda W J H Penninx, Dorret I Boomsma, Panos Deloukas, Timothy D Spector, Luigi Ferrucci, Antonio Cao, Angelo Scuteri, David Schlessinger, Manuela Uda, Aimo Ruokonen, Marjo-Riitta Jarvelin, Dawn M Waterworth, Peter Vollenweider, Leena Peltonen, Vincent Mooser, Robert Sladek	Nicholette D Palmer	Robert Sladek	Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America. nallred@wfubmc.edu	NHLBI NIH HHS; R01 HL56266
Chen HK, Liu Z, Meyer-Franke A, Brodbeck J, Miranda RD, McGuire JG, Pleiss MA, Ji ZS, Balestra ME, Walker DW, Xu Q, Jeong DE, Budamagunta MS, Voss JC, Freedman SB, Weisgraber KH, Huang Y, Mahley RW	Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons.	J. Biol. Chem.	287:8:5253-66	2012	22158868		Hung-Kai Chen, Zhaoping Liu, Anke Meyer-Franke, Jens Brodbeck, Rene D Miranda, James G McGuire, Michael A Pleiss, Zhong-Sheng Ji, Maureen E Balestra, David W Walker, Qin Xu, Dah-eun Jeong, Madhu S Budamagunta, John C Voss, Stephen B Freedman, Karl H Weisgraber, Yadong Huang, Robert W Mahley	Hung-Kai Chen	Robert W Mahley	Gladstone Center for Translational Research, San Francisco, California 94158, USA.	NIA NIH HHS; R01 AG029246
Hodoğlugil U, Williamson DW, Yu Y, Farrer LA, Mahley RW	Glucuronic acid epimerase is associated with plasma triglyceride and high-density lipoprotein cholesterol levels in Turks.	Ann. Hum. Genet.	75:3:398-417	2011	21488854		Uğur Hodoğlugil, David W Williamson, Yi Yu, Lindsay A Farrer, Robert W Mahley	Uğur Hodoğlugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, CA, USA.	NHLBI NIH HHS; R01 HL71027
Brodbeck J, McGuire J, Liu Z, Meyer-Franke A, Balestra ME, Jeong DE, Pleiss M, McComas C, Hess F, Witter D, Peterson S, Childers M, Goulet M, Liverton N, Hargreaves R, Freedman S, Weisgraber KH, Mahley RW, Huang Y	Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors.	J. Biol. Chem.	286:19:17217-26	2011	21454574		Jens Brodbeck, Jim McGuire, Zhaoping Liu, Anke Meyer-Franke, Maureen E Balestra, Dah-eun Jeong, Mike Pleiss, Casey McComas, Fred Hess, David Witter, Scott Peterson, Matthew Childers, Mark Goulet, Nigel Liverton, Richard Hargreaves, Stephen Freedman, Karl H Weisgraber, Robert W Mahley, Yadong Huang	Jens Brodbeck	Yadong Huang	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94158, USA.	NIA NIH HHS; P01 AG022074
Chen HK, Ji ZS, Dodson SE, Miranda RD, Rosenblum CI, Reynolds IJ, Freedman SB, Weisgraber KH, Huang Y, Mahley RW	Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease.	J. Biol. Chem.	286:7:5215-21	2011	21118811		Hung-Kai Chen, Zhong-Sheng Ji, Sara E Dodson, Rene D Miranda, Charles I Rosenblum, Ian J Reynolds, Stephen B Freedman, Karl H Weisgraber, Yadong Huang, Robert W Mahley	Hung-Kai Chen	Robert W Mahley	Gladstone Center for Translational Research, San Francisco, California 94158, USA.	NA
Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, Luan J, Ashford S, Wheeler E, Young EH, Hadley D, Thompson JR, Braund PS, Johnson T, Struchalin M, Surakka I, Luben R, Khaw KT, Rodwell SA, Loos RJ, Boekholdt SM, Inouye M, Deloukas P, Elliott P, Schlessinger D, Sanna S, Scuteri A, Jackson A, Mohlke KL, Tuomilehto J, Roberts R, Stewart A, Kesäniemi YA, Mahley RW, Grundy SM, McArdle W, Cardon L, Waeber G, Vollenweider P, Chambers JC, Boehnke M, Abecasis GR, Salomaa V, Järvelin MR, Ruokonen A, Barroso I, Epstein SE, Hakonarson HH, Rader DJ, Reilly MP, Witteman JC, Hall AS, Samani NJ, Strachan DP, Barter P, van Duijn CM, Kooner JS, Peltonen L, Wareham NJ, McPherson R, Mooser V, Sandhu MS	Genetic variants influencing circulating lipid levels and risk of coronary artery disease.	Arterioscler. Thromb. Vasc. Biol.	30:11:2264-76	2010	20864672		Dawn M Waterworth, Sally L Ricketts, Kijoung Song, Li Chen, Jing Hua Zhao, Samuli Ripatti, Yurii S Aulchenko, Weihua Zhang, Xin Yuan, Noha Lim, Jian'an Luan, Sofie Ashford, Eleanor Wheeler, Elizabeth H Young, David Hadley, John R Thompson, Peter S Braund, Toby Johnson, Maksim Struchalin, Ida Surakka, Robert Luben, Kay-Tee Khaw, Sheila A Rodwell, Ruth J F Loos, S Matthijs Boekholdt, Michael Inouye, Panagiotis Deloukas, Paul Elliott, David Schlessinger, Serena Sanna, Angelo Scuteri, Anne Jackson, Karen L Mohlke, Jaako Tuomilehto, Robert Roberts, Alexandre Stewart, Y Antero Kesäniemi, Robert W Mahley, Scott M Grundy, Wendy McArdle, Lon Cardon, Gérard Waeber, Peter Vollenweider, John C Chambers, Michael Boehnke, Gonçalo R Abecasis, Veikko Salomaa, Marjo-Riitta Järvelin, Aimo Ruokonen, Inês Barroso, Stephen E Epstein, Hakon H Hakonarson, Daniel J Rader, Muredach P Reilly, Jacqueline C M Witteman, Alistair S Hall, Nilesh J Samani, David P Strachan, Philip Barter, Cornelia M van Duijn, Jaspal S Kooner, Leena Peltonen, Nicholas J Wareham, Ruth McPherson, Vincent Mooser, Manjinder S Sandhu	Dawn M Waterworth	Manjinder S Sandhu	Genetics Division, GlaxoSmithKline R&D, King of Prussia, PA, USA.	NIDDK NIH HHS; U01 DK062418
Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, Berrettini W, Knouff CW, Yuan X, Waeber G, Vollenweider P, Preisig M, Wareham NJ, Zhao JH, Loos RJ, Barroso I, Khaw KT, Grundy S, Barter P, Mahley R, Kesaniemi A, McPherson R, Vincent JB, Strauss J, Kennedy JL, Farmer A, McGuffin P, Day R, Matthews K, Bakke P, Gulsvik A, Lucae S, Ising M, Brueckl T, Horstmann S, Wichmann HE, Rawal R, Dahmen N, Lamina C, Polasek O, Zgaga L, Huffman J, Campbell S, Kooner J, Chambers JC, Burnett MS, Devaney JM, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Epstein S, Wilson JF, Wild SH, Campbell H, Vitart V, Reilly MP, Li M, Qu L, Wilensky R, Matthai W, Hakonarson HH, Rader DJ, Franke A, Wittig M, Schäfer A, Uda M, Terracciano A, Xiao X, Busonero F, Scheet P, Schlessinger D, St Clair D, Rujescu D, Abecasis GR, Grabe HJ, Teumer A, Völzke H, Petersmann A, John U, Rudan I, Hayward C, Wright AF, Kolcic I, Wright BJ, Thompson JR, Balmforth AJ, Hall AS, Samani NJ, Anderson CA, Ahmad T, Mathew CG, Parkes M, Satsangi J, Caulfield M, Munroe PB, Farrall M, Dominiczak A, Worthington J, Thomson W, Eyre S, Barton A, Mooser V, Francks C, Marchini J	Meta-analysis and imputation refines the association of 15q25 with smoking quantity.	Nat. Genet.	42:5:436-40	2010	20418889		Jason Z Liu, Federica Tozzi, Dawn M Waterworth, Sreekumar G Pillai, Pierandrea Muglia, Lefkos Middleton, Wade Berrettini, Christopher W Knouff, Xin Yuan, Gérard Waeber, Peter Vollenweider, Martin Preisig, Nicholas J Wareham, Jing Hua Zhao, Ruth J F Loos, Inês Barroso, Kay-Tee Khaw, Scott Grundy, Philip Barter, Robert Mahley, Antero Kesaniemi, Ruth McPherson, John B Vincent, John Strauss, James L Kennedy, Anne Farmer, Peter McGuffin, Richard Day, Keith Matthews, Per Bakke, Amund Gulsvik, Susanne Lucae, Marcus Ising, Tanja Brueckl, Sonja Horstmann, H-Erich Wichmann, Rajesh Rawal, Norbert Dahmen, Claudia Lamina, Ozren Polasek, Lina Zgaga, Jennifer Huffman, Susan Campbell, Jaspal Kooner, John C Chambers, Mary Susan Burnett, Joseph M Devaney, Augusto D Pichard, Kenneth M Kent, Lowell Satler, Joseph M Lindsay, Ron Waksman, Stephen Epstein, James F Wilson, Sarah H Wild, Harry Campbell, Veronique Vitart, Muredach P Reilly, Mingyao Li, Liming Qu, Robert Wilensky, William Matthai, Hakon H Hakonarson, Daniel J Rader, Andre Franke, Michael Wittig, Arne Schäfer, Manuela Uda, Antonio Terracciano, Xiangjun Xiao, Fabio Busonero, Paul Scheet, David Schlessinger, David St Clair, Dan Rujescu, Gonçalo R Abecasis, Hans Jörgen Grabe, Alexander Teumer, Henry Völzke, Astrid Petersmann, Ulrich John, Igor Rudan, Caroline Hayward, Alan F Wright, Ivana Kolcic, Benjamin J Wright, John R Thompson, Anthony J Balmforth, Alistair S Hall, Nilesh J Samani, Carl A Anderson, Tariq Ahmad, Christopher G Mathew, Miles Parkes, Jack Satsangi, Mark Caulfield, Patricia B Munroe, Martin Farrall, Anna Dominiczak, Jane Worthington, Wendy Thomson, Steve Eyre, Anne Barton, Vincent Mooser, Clyde Francks, Jonathan Marchini	Jason Z Liu	Jonathan Marchini	Department of Statistics, University of Oxford, Oxford, UK.	NIA NIH HHS; ZIA AG000196-04
Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, Wheeler E, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, Randall J, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P, Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, Perry JR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ, Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ, Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Fox CS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, Grundy S, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, Hartikainen AL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR, Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V, Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S, Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W, Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, Tuomi T, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H, Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM, Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV, Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, Marmot M, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O, Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H, Wilson JF, Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, Altshuler D, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD, Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ, Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI, Florez JC, Barroso I	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	Nat. Genet.	42:2:105-16	2010	20081858		Josée Dupuis, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Nicole Soranzo, Anne U Jackson, Eleanor Wheeler, Nicole L Glazer, Nabila Bouatia-Naji, Anna L Gloyn, Cecilia M Lindgren, Reedik Mägi, Andrew P Morris, Joshua Randall, Toby Johnson, Paul Elliott, Denis Rybin, Gudmar Thorleifsson, Valgerdur Steinthorsdottir, Peter Henneman, Harald Grallert, Abbas Dehghan, Jouke Jan Hottenga, Christopher S Franklin, Pau Navarro, Kijoung Song, Anuj Goel, John R B Perry, Josephine M Egan, Taina Lajunen, Niels Grarup, Thomas Sparsø, Alex Doney, Benjamin F Voight, Heather M Stringham, Man Li, Stavroula Kanoni, Peter Shrader, Christine Cavalcanti-Proença, Meena Kumari, Lu Qi, Nicholas J Timpson, Christian Gieger, Carina Zabena, Ghislain Rocheleau, Erik Ingelsson, Ping An, Jeffrey O'Connell, Jian'an Luan, Amanda Elliott, Steven A McCarroll, Felicity Payne, Rosa Maria Roccasecca, François Pattou, Praveen Sethupathy, Kristin Ardlie, Yavuz Ariyurek, Beverley Balkau, Philip Barter, John P Beilby, Yoav Ben-Shlomo, Rafn Benediktsson, Amanda J Bennett, Sven Bergmann, Murielle Bochud, Eric Boerwinkle, Amélie Bonnefond, Lori L Bonnycastle, Knut Borch-Johnsen, Yvonne Böttcher, Eric Brunner, Suzannah J Bumpstead, Guillaume Charpentier, Yii-Der Ida Chen, Peter Chines, Robert Clarke, Lachlan J M Coin, Matthew N Cooper, Marilyn Cornelis, Gabe Crawford, Laura Crisponi, Ian N M Day, Eco J C de Geus, Jerome Delplanque, Christian Dina, Michael R Erdos, Annette C Fedson, Antje Fischer-Rosinsky, Nita G Forouhi, Caroline S Fox, Rune Frants, Maria Grazia Franzosi, Pilar Galan, Mark O Goodarzi, Jürgen Graessler, Christopher J Groves, Scott Grundy, Rhian Gwilliam, Ulf Gyllensten, Samy Hadjadj, Göran Hallmans, Naomi Hammond, Xijing Han, Anna-Liisa Hartikainen, Neelam Hassanali, Caroline Hayward, Simon C Heath, Serge Hercberg, Christian Herder, Andrew A Hicks, David R Hillman, Aroon D Hingorani, Albert Hofman, Jennie Hui, Joe Hung, Bo Isomaa, Paul R V Johnson, Torben Jørgensen, Antti Jula, Marika Kaakinen, Jaakko Kaprio, Y Antero Kesaniemi, Mika Kivimaki, Beatrice Knight, Seppo Koskinen, Peter Kovacs, Kirsten Ohm Kyvik, G Mark Lathrop, Debbie A Lawlor, Olivier Le Bacquer, Cécile Lecoeur, Yun Li, Valeriya Lyssenko, Robert Mahley, Massimo Mangino, Alisa K Manning, María Teresa Martínez-Larrad, Jarred B McAteer, Laura J McCulloch, Ruth McPherson, Christa Meisinger, David Melzer, David Meyre, Braxton D Mitchell, Mario A Morken, Sutapa Mukherjee, Silvia Naitza, Narisu Narisu, Matthew J Neville, Ben A Oostra, Marco Orrù, Ruth Pakyz, Colin N A Palmer, Giuseppe Paolisso, Cristian Pattaro, Daniel Pearson, John F Peden, Nancy L Pedersen, Markus Perola, Andreas F H Pfeiffer, Irene Pichler, Ozren Polasek, Danielle Posthuma, Simon C Potter, Anneli Pouta, Michael A Province, Bruce M Psaty, Wolfgang Rathmann, Nigel W Rayner, Kenneth Rice, Samuli Ripatti, Fernando Rivadeneira, Michael Roden, Olov Rolandsson, Annelli Sandbaek, Manjinder Sandhu, Serena Sanna, Avan Aihie Sayer, Paul Scheet, Laura J Scott, Udo Seedorf, Stephen J Sharp, Beverley Shields, Gunnar Sigurethsson, Eric J G Sijbrands, Angela Silveira, Laila Simpson, Andrew Singleton, Nicholas L Smith, Ulla Sovio, Amy Swift, Holly Syddall, Ann-Christine Syvänen, Toshiko Tanaka, Barbara Thorand, Jean Tichet, Anke Tönjes, Tiinamaija Tuomi, André G Uitterlinden, Ko Willems van Dijk, Mandy van Hoek, Dhiraj Varma, Sophie Visvikis-Siest, Veronique Vitart, Nicole Vogelzangs, Gérard Waeber, Peter J Wagner, Andrew Walley, G Bragi Walters, Kim L Ward, Hugh Watkins, Michael N Weedon, Sarah H Wild, Gonneke Willemsen, Jaqueline C M Witteman, John W G Yarnell, Eleftheria Zeggini, Diana Zelenika, Björn Zethelius, Guangju Zhai, Jing Hua Zhao, M Carola Zillikens, Ingrid B Borecki, Ruth J F Loos, Pierre Meneton, Patrik K E Magnusson, David M Nathan, Gordon H Williams, Andrew T Hattersley, Kaisa Silander, Veikko Salomaa, George Davey Smith, Stefan R Bornstein, Peter Schwarz, Joachim Spranger, Fredrik Karpe, Alan R Shuldiner, Cyrus Cooper, George V Dedoussis, Manuel Serrano-Ríos, Andrew D Morris, Lars Lind, Lyle J Palmer, Frank B Hu, Paul W Franks, Shah Ebrahim, Michael Marmot, W H Linda Kao, James S Pankow, Michael J Sampson, Johanna Kuusisto, Markku Laakso, Torben Hansen, Oluf Pedersen, Peter Paul Pramstaller, H Erich Wichmann, Thomas Illig, Igor Rudan, Alan F Wright, Michael Stumvoll, Harry Campbell, James F Wilson, Richard N Bergman, Thomas A Buchanan, Francis S Collins, Karen L Mohlke, Jaakko Tuomilehto, Timo T Valle, David Altshuler, Jerome I Rotter, David S Siscovick, Brenda W J H Penninx, Dorret I Boomsma, Panos Deloukas, Timothy D Spector, Timothy M Frayling, Luigi Ferrucci, Augustine Kong, Unnur Thorsteinsdottir, Kari Stefansson, Cornelia M van Duijn, Yurii S Aulchenko, Antonio Cao, Angelo Scuteri, David Schlessinger, Manuela Uda, Aimo Ruokonen, Marjo-Riitta Jarvelin, Dawn M Waterworth, Peter Vollenweider, Leena Peltonen, Vincent Mooser, Goncalo R Abecasis, Nicholas J Wareham, Robert Sladek, Philippe Froguel, Richard M Watanabe, James B Meigs, Leif Groop, Michael Boehnke, Mark I McCarthy, Jose C Florez, Inês Barroso	Josée Dupuis	Inês Barroso	Department of Biostatistics, Boston University School of Public Health, Massachusetts, USA.	NIDDK NIH HHS; R01 DK078616-01A1
Richards JB, Waterworth D, O'Rahilly S, Hivert MF, Loos RJ, Perry JR, Tanaka T, Timpson NJ, Semple RK, Soranzo N, Song K, Rocha N, Grundberg E, Dupuis J, Florez JC, Langenberg C, Prokopenko I, Saxena R, Sladek R, Aulchenko Y, Evans D, Waeber G, Erdmann J, Burnett MS, Sattar N, Devaney J, Willenborg C, Hingorani A, Witteman JC, Vollenweider P, Glaser B, Hengstenberg C, Ferrucci L, Melzer D, Stark K, Deanfield J, Winogradow J, Grassl M, Hall AS, Egan JM, Thompson JR, Ricketts SL, König IR, Reinhard W, Grundy S, Wichmann HE, Barter P, Mahley R, Kesaniemi YA, Rader DJ, Reilly MP, Epstein SE, Stewart AF, Van Duijn CM, Schunkert H, Burling K, Deloukas P, Pastinen T, Samani NJ, McPherson R, Davey Smith G, Frayling TM, Wareham NJ, Meigs JB, Mooser V, Spector TD	A genome-wide association study reveals variants in ARL15 that influence adiponectin levels.	PLoS Genet.	5:12:e1000768	2009	20011104		J Brent Richards, Dawn Waterworth, Stephen O'Rahilly, Marie-France Hivert, Ruth J F Loos, John R B Perry, Toshiko Tanaka, Nicholas John Timpson, Robert K Semple, Nicole Soranzo, Kijoung Song, Nuno Rocha, Elin Grundberg, Josée Dupuis, Jose C Florez, Claudia Langenberg, Inga Prokopenko, Richa Saxena, Robert Sladek, Yurii Aulchenko, David Evans, Gerard Waeber, Jeanette Erdmann, Mary-Susan Burnett, Naveed Sattar, Joseph Devaney, Christina Willenborg, Aroon Hingorani, Jaquelin C M Witteman, Peter Vollenweider, Beate Glaser, Christian Hengstenberg, Luigi Ferrucci, David Melzer, Klaus Stark, John Deanfield, Janina Winogradow, Martina Grassl, Alistair S Hall, Josephine M Egan, John R Thompson, Sally L Ricketts, Inke R König, Wibke Reinhard, Scott Grundy, H-Erich Wichmann, Phil Barter, Robert Mahley, Y Antero Kesaniemi, Daniel J Rader, Muredach P Reilly, Stephen E Epstein, Alexandre F R Stewart, Cornelia M Van Duijn, Heribert Schunkert, Keith Burling, Panos Deloukas, Tomi Pastinen, Nilesh J Samani, Ruth McPherson, George Davey Smith, Timothy M Frayling, Nicholas J Wareham, James B Meigs, Vincent Mooser, Tim D Spector	J Brent Richards	Tim D Spector	Departments of Medicine, Human Genetics, and Epidemiology and Biostatistics, Jewish General Hospital, McGill University, Montréal, Québec, Canada. brent.richards@mcgill.ca	Medical Research Council; 
Li G, Bien-Ly N, Andrews-Zwilling Y, Xu Q, Bernardo A, Ring K, Halabisky B, Deng C, Mahley RW, Huang Y	GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice.	Cell Stem Cell	5:6:634-45	2009	19951691		Gang Li, Nga Bien-Ly, Yaisa Andrews-Zwilling, Qin Xu, Aubrey Bernardo, Karen Ring, Brian Halabisky, Changhui Deng, Robert W Mahley, Yadong Huang	Gang Li	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; P01 AG022074-06
Hodoglugil U, Williamson DW, Mahley RW	Polymorphisms in the hepatic lipase gene affect plasma HDL-cholesterol levels in a Turkish population.	J. Lipid Res.	51:2:422-30	2010	19734193		Ugur Hodoglugil, David W Williamson, Robert W Mahley	Ugur Hodoglugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA, USA.	NHLBI NIH HHS; R01 HL71027
Mahley RW, Huang Y	Alzheimer disease: multiple causes, multiple effects of apolipoprotein E4, and multiple therapeutic approaches.	Ann. Neurol.	65:6:623-5	2009	19557874		Robert W Mahley, Yadong Huang	Robert W Mahley	Yadong Huang		NIA NIH HHS; P01 AG022074
Mahley RW, Weisgraber KH, Huang Y	Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS.	J. Lipid Res.	50 Suppl:S183-8	2009	19106071		Robert W Mahley, Karl H Weisgraber, Yadong Huang	Robert W Mahley	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. rmahley@gladstone.ucsf.edu	NIA NIH HHS; R01 AG028793
Tanyolaç S, Mahley RW, Hodoglugil U, Goldfine ID	Gender differences in the relationship of ENPP1/PC-1 variants to obesity in a Turkish population.	Obesity (Silver Spring)	16:11:2468-71	2008	18719658		Sinan Tanyolaç, Robert W Mahley, Uğur Hodoglugil, Ira D Goldfine	Sinan Tanyolaç	Ira D Goldfine	Department of Medicine and Diabetes Center, University of California, San Francisco/Mt. Zion Medical Center, San Francisco, California, USA.	NIDDK NIH HHS; DK056933
Burt TD, Agan BK, Marconi VC, He W, Kulkarni H, Mold JE, Cavrois M, Huang Y, Mahley RW, Dolan MJ, McCune JM, Ahuja SK	Apolipoprotein (apo) E4 enhances HIV-1 cell entry in vitro, and the APOE epsilon4/epsilon4 genotype accelerates HIV disease progression.	Proc. Natl. Acad. Sci. U.S.A.	105:25:8718-23	2008	18562290		Trevor D Burt, Brian K Agan, Vincent C Marconi, Weijing He, Hemant Kulkarni, Jeffrey E Mold, Marielle Cavrois, Yadong Huang, Robert W Mahley, Matthew J Dolan, Joseph M McCune, Sunil K Ahuja	Trevor D Burt	Sunil K Ahuja	Division of Experimental Medicine, Department of Medicine, and Division of Neonatology, Department of Pediatrics, University of California, San Francisco, CA 94110, USA.	NA
Sandhu MS, Waterworth DM, Debenham SL, Wheeler E, Papadakis K, Zhao JH, Song K, Yuan X, Johnson T, Ashford S, Inouye M, Luben R, Sims M, Hadley D, McArdle W, Barter P, Kesäniemi YA, Mahley RW, McPherson R, Grundy SM, Bingham SA, Khaw KT, Loos RJ, Waeber G, Barroso I, Strachan DP, Deloukas P, Vollenweider P, Wareham NJ, Mooser V	LDL-cholesterol concentrations: a genome-wide association study.	Lancet	371:9611:483-91	2008	18262040		Manjinder S Sandhu, Dawn M Waterworth, Sally L Debenham, Eleanor Wheeler, Konstantinos Papadakis, Jing Hua Zhao, Kijoung Song, Xin Yuan, Toby Johnson, Sofie Ashford, Michael Inouye, Robert Luben, Matthew Sims, David Hadley, Wendy McArdle, Philip Barter, Y Antero Kesäniemi, Robert W Mahley, Ruth McPherson, Scott M Grundy, Sheila A Bingham, Kay-Tee Khaw, Ruth J F Loos, Gérard Waeber, Inês Barroso, David P Strachan, Panagiotis Deloukas, Peter Vollenweider, Nicholas J Wareham, Vincent Mooser	Manjinder S Sandhu	Vincent Mooser	Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge, Cambridge, UK. manj.sandhu@srl.cam.ac.uk	Wellcome Trust; 068545/Z/02
Brodbeck J, Balestra ME, Saunders AM, Roses AD, Mahley RW, Huang Y	Rosiglitazone increases dendritic spine density and rescues spine loss caused by apolipoprotein E4 in primary cortical neurons.	Proc. Natl. Acad. Sci. U.S.A.	105:4:1343-6	2008	18212130		Jens Brodbeck, Maureen E Balestra, Ann M Saunders, Allen D Roses, Robert W Mahley, Yadong Huang	Jens Brodbeck	Yadong Huang	Gladstone Institute of Neurological Disease and Gladstone Institute of Cardiovascular Disease, The J. David Gladstone Institutes, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Mahley RW, Huang Y, Weisgraber KH	Detrimental effects of apolipoprotein E4: potential therapeutic targets in Alzheimer's disease.	Curr Alzheimer Res	4:5:537-40	2007	18220516		Robert W Mahley, Yadong Huang, Karl H Weisgraber	Robert W Mahley	Karl H Weisgraber	Gladstone Institute of Neurological Disease 1650 Owens Street, San Francisco, CA 94158, USA. rmahley@gladstone.ucsf.edu	NIA NIH HHS; P01 AG022074
Mahley RW, Huang Y	Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing.	J. Clin. Invest.	117:1:94-8	2007	17200713		Robert W Mahley, Yadong Huang	Robert W Mahley	Yadong Huang	Gladstone Institute of Neurological Disease and Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. rmahley@gladstone.ucsf.edu	NA
Safar JG, Wille H, Geschwind MD, Deering C, Latawiec D, Serban A, King DJ, Legname G, Weisgraber KH, Mahley RW, Miller BL, Dearmond SJ, Prusiner SB	Human prions and plasma lipoproteins.	Proc. Natl. Acad. Sci. U.S.A.	103:30:11312-7	2006	16849426		Jiri G Safar, Holger Wille, Michael D Geschwind, Camille Deering, Diane Latawiec, Ana Serban, David J King, Giuseppe Legname, Karl H Weisgraber, Robert W Mahley, Bruce L Miller, Stephen J Dearmond, Stanley B Prusiner	Jiri G Safar	Stanley B Prusiner	Institute for Neurodegenerative Diseases, Department of Neurology, University of California, San Francisco, CA 94143, USA.	NCRR NIH HHS; RR00079
Roses AD, Saunders AM, Huang Y, Strum J, Weisgraber KH, Mahley RW	Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease).	Pharmacogenomics J.	7:1:10-28	2007	16770341		A D Roses, A M Saunders, Y Huang, J Strum, K H Weisgraber, R W Mahley	A D Roses	R W Mahley	Genetics Research, GlaxoSmithKline Research and Development, NC 27709, USA. allen.d.roses@gsk.com	NA
Xu Q, Bernardo A, Walker D, Kanegawa T, Mahley RW, Huang Y	Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.	J. Neurosci.	26:19:4985-94	2006	16687490		Qin Xu, Aubrey Bernardo, David Walker, Tiffany Kanegawa, Robert W Mahley, Yadong Huang	Qin Xu	Yadong Huang	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA.	NHLBI NIH HHS; R01 HL37063
Mahley RW, Huang Y, Weisgraber KH	Putting cholesterol in its place: apoE and reverse cholesterol transport.	J. Clin. Invest.	116:5:1226-9	2006	16670767		Robert W Mahley, Yadong Huang, Karl H Weisgraber	Robert W Mahley	Karl H Weisgraber	Gladstone Institute of Neurological Disease and Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. rmahley@gladstone.ucsf.edu	NA
Huang Y, Mahley RW	Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Apolipoprotein E and the mitochondrial metabolic hypothesis.	Alzheimers Dement	2:2:71-3	2006	19595858		Yadong Huang, Robert W Mahley	Yadong Huang	Robert W Mahley	Gladstone Institute of Neurological Disease, Department of Pathology, University of California, San Francisco, CA, USA. yhuang@gladstone.ucsf.edu	NIA NIH HHS; P01 AG022074
Mahley RW, Weisgraber KH, Huang Y	Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease.	Proc. Natl. Acad. Sci. U.S.A.	103:15:5644-51	2006	16567625		Robert W Mahley, Karl H Weisgraber, Yadong Huang	Robert W Mahley	Yadong Huang	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, CA 94158, USA. rmahley@gladstone.ucsf.edu	NIA NIH HHS; P01 AG022074
Hodoğlugil U, Mahley RW	Smoking and obesity make a bad problem worse: genetics and lifestyle affect high density lipoprotein levels in Turks.	Anadolu Kardiyol Derg	6:1:60-7	2006	16524804		Uğur Hodoğlugil, Robert W Mahley	Uğur Hodoğlugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA.	NA
Mahley RW, Huang Y	Apolipoprotein (apo) E4 and Alzheimer's disease: unique conformational and biophysical properties of apoE4 can modulate neuropathology.	Acta Neurol. Scand., Suppl.c	185:8-14	2006	16866905		R W Mahley, Y Huang	R W Mahley	Y Huang	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA. rmahley@gladstone.ucsf.edu	NINDS NIH HHS; R21 NS046465
Ye S, Huang Y, Müllendorff K, Dong L, Giedt G, Meng EC, Cohen FE, Kuntz ID, Weisgraber KH, Mahley RW	Apolipoprotein (apo) E4 enhances amyloid beta peptide production in cultured neuronal cells: apoE structure as a potential therapeutic target.	Proc. Natl. Acad. Sci. U.S.A.	102:51:18700-5	2005	16344478		Shiming Ye, Yadong Huang, Karin Müllendorff, Liming Dong, Gretchen Giedt, Elaine C Meng, Fred E Cohen, Irwin D Kuntz, Karl H Weisgraber, Robert W Mahley	Shiming Ye	Robert W Mahley	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NINDS NIH HHS; NS46465
Chang S, ran Ma T, Miranda RD, Balestra ME, Mahley RW, Huang Y	Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity.	Proc. Natl. Acad. Sci. U.S.A.	102:51:18694-9	2005	16344479		Shengjun Chang, Tian ran Ma, R Dennis Miranda, Maureen E Balestra, Robert W Mahley, Yadong Huang	Shengjun Chang	Yadong Huang	Gladstone Institute of Neurological Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01HL37063
Ji ZS, Müllendorff K, Cheng IH, Miranda RD, Huang Y, Mahley RW	Reactivity of apolipoprotein E4 and amyloid beta peptide: lysosomal stability and neurodegeneration.	J. Biol. Chem.	281:5:2683-92	2006	16298992		Zhong-Sheng Ji, Karin Müllendorff, Irene H Cheng, R Dennis Miranda, Yadong Huang, Robert W Mahley	Zhong-Sheng Ji	Robert W Mahley	Gladstone Institute of Neurological Disease, Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94158,USA.	NINDS NIH HHS; R21 NS046465
Hodoglugil U, Tanyolaç S, Williamson DW, Huang Y, Mahley RW	Apolipoprotein A-V: a potential modulator of plasma triglyceride levels in Turks.	J. Lipid Res.	47:1:144-53	2006	16258166		Ugur Hodoglugil, Sinan Tanyolaç, David W Williamson, Yadong Huang, Robert W Mahley	Ugur Hodoglugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA, USA.	NHLBI NIH HHS; R01 HL-71027
Hodoğlugil U, Williamson DW, Huang Y, Mahley RW	An interaction between the TaqIB polymorphism of cholesterol ester transfer protein and smoking is associated with changes in plasma high-density lipoprotein cholesterol levels in Turks.	Clin. Genet.	68:2:118-27	2005	15996208		U Hodoğlugil, D W Williamson, Y Huang, R W Mahley	U Hodoğlugil	R W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.	NHLBI NIH HHS; HL71027
Hodoğlugil U, Williamson DW, Huang Y, Mahley RW	Common polymorphisms of ATP binding cassette transporter A1, including a functional promoter polymorphism, associated with plasma high density lipoprotein cholesterol levels in Turks.	Atherosclerosis	183:2:199-212	2005	15935359		Uğur Hodoğlugil, David W Williamson, Yadong Huang, Robert W Mahley	Uğur Hodoğlugil	Robert W Mahley	Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA.	NHLBI NIH HHS; R01 HL71027
Harris FM, Brecht WJ, Xu Q, Mahley RW, Huang Y	Increased tau phosphorylation in apolipoprotein E4 transgenic mice is associated with activation of extracellular signal-regulated kinase: modulation by zinc.	J. Biol. Chem.	279:43:44795-801	2004	15322121		Faith M Harris, Walter J Brecht, Qin Xu, Robert W Mahley, Yadong Huang	Faith M Harris	Yadong Huang	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NINDS NIH HHS; R21 NS046465
Xu Q, Brecht WJ, Weisgraber KH, Mahley RW, Huang Y	Apolipoprotein E4 domain interaction occurs in living neuronal cells as determined by fluorescence resonance energy transfer.	J. Biol. Chem.	279:24:25511-6	2004	15054100		Qin Xu, Walter J Brecht, Karl H Weisgraber, Robert W Mahley, Yadong Huang	Qin Xu	Yadong Huang	Gladstone Institute of Neurological Disease, University of California, San Francisco, CA 94141, USA.	NINDS NIH HHS; R21 NS046465
Harris FM, Tesseur I, Brecht WJ, Xu Q, Mullendorff K, Chang S, Wyss-Coray T, Mahley RW, Huang Y	Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease.	J. Biol. Chem.	279:5:3862-8	2004	14585838		Faith M Harris, Ina Tesseur, Walter J Brecht, Qin Xu, Karin Mullendorff, Shengjun Chang, Tony Wyss-Coray, Robert W Mahley, Yadong Huang	Faith M Harris	Yadong Huang	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; R01 HL37063
Ji ZS, Miranda RD, Newhouse YM, Weisgraber KH, Huang Y, Mahley RW	Apolipoprotein E4 potentiates amyloid beta peptide-induced lysosomal leakage and apoptosis in neuronal cells.	J. Biol. Chem.	277:24:21821-8	2002	11912196		Zhong-Sheng Ji, R Dennis Miranda, Yvonne M Newhouse, Karl H Weisgraber, Yadong Huang, Robert W Mahley	Zhong-Sheng Ji	Robert W Mahley	Gladstone Institute of Neurological Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL47660
Huang Y, Liu XQ, Wyss-Coray T, Brecht WJ, Sanan DA, Mahley RW	Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons.	Proc. Natl. Acad. Sci. U.S.A.	98:15:8838-43	2001	11447277		Y Huang, X Q Liu, T Wyss-Coray, W J Brecht, D A Sanan, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Neurological Disease, P.O. Box 419100, San Francisco, CA 94141-9100, USA. yhuang@gladstone.ucsf.edu	NA
Dichek HL, Johnson SM, Akeefe H, Lo GT, Sage E, Yap CE, Mahley RW	Hepatic lipase overexpression lowers remnant and LDL levels by a noncatalytic mechanism in LDL receptor-deficient mice.	J. Lipid Res.	42:2:201-10	2001	11181749		H L Dichek, S M Johnson, H Akeefe, G T Lo, E Sage, C E Yap, R W Mahley	H L Dichek	R W Mahley	Children's Hospital Oakland Research Institute (CHORI), Oakland, CA 94609, USA.hdichek@chori.org	NHLBI NIH HHS; KO8 HL 04031
Nguyen TT, Kruckeberg KE, O'Brien JF, Ji ZS, Karnes PS, Crotty TB, Hay ID, Mahley RW, O'Brien T	Familial splenomegaly: macrophage hypercatabolism of lipoproteins associated with apolipoprotein E mutation [apolipoprotein E (delta149 Leu)].	J. Clin. Endocrinol. Metab.	85:11:4354-8	2000	11095479		T T Nguyen, K E Kruckeberg, J F O'Brien, Z S Ji, P S Karnes, T B Crotty, I D Hay, R W Mahley, T O'Brien	T T Nguyen	T O'Brien	Divisions of Endocrinology, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA. nguyen.tu@mayo.edu	NA
Mahley RW, Rall SC	Apolipoprotein E: far more than a lipid transport protein.	Annu Rev Genomics Hum Genet	1:507-37	2000	11701639		R W Mahley, S C Rall	R W Mahley	S C Rall	Gladstone Institute of Cardiovascular Disease, University of California at San Francisco, San Francisco, California 94141-9100, USA. rmahley@gladstone.ucsf.edu	NHLBI NIH HHS; HL47660
Langer C, Huang Y, Cullen P, Wiesenhütter B, Mahley RW, Assmann G, von Eckardstein A	Endogenous apolipoprotein E modulates cholesterol efflux and cholesteryl ester hydrolysis mediated by high-density lipoprotein-3 and lipid-free apolipoproteins in mouse peritoneal macrophages.	J. Mol. Med.	78:4:217-27	2000	10933584		C Langer, Y Huang, P Cullen, B Wiesenhütter, R W Mahley, G Assmann, A von Eckardstein	C Langer	A von Eckardstein	Institute of Arteriosclerosis Research, Münster, Germany.	NA
Huang Y, Ji ZS, Brecht WJ, Rall SC, Taylor JM, Mahley RW	Overexpression of apolipoprotein E3 in transgenic rabbits causes combined hyperlipidemia by stimulating hepatic VLDL production and impairing VLDL lipolysis.	Arterioscler. Thromb. Vasc. Biol.	19:12:2952-9	1999	10591675		Y Huang, Z S Ji, W J Brecht, S C Rall, J M Taylor, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL51588
Mahley RW, Huang Y, Rall SC	Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia). Questions, quandaries, and paradoxes.	J. Lipid Res.	40:11:1933-49	1999	10552997		R W Mahley, Y Huang, S C Rall	R W Mahley	S C Rall	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL47660
Mahley RW, Rall SC	Is epsilon4 the ancestral human apoE allele?	Neurobiol. Aging	20:4:429-30		10604434		R W Mahley, S C Rall	R W Mahley	S C Rall	Gladstone Institute of Neurological Disease, and University of California, San Francisco 94141-9100, USA. rmahley@gladstone.ucsf.edu	NA
Mahley RW, Huang Y	Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond.	Curr. Opin. Lipidol.	10:3:207-17	1999	10431657		R W Mahley, Y Huang	R W Mahley	Y Huang	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA. rmahley@gladstone.ucsf.edu	NHLBI NIH HHS; HL47660
Orth M, Weng W, Funke H, Steinmetz A, Assmann G, Nauck M, Dierkes J, Ambrosch A, Weisgraber KH, Mahley RW, Wieland H, Luley C	Effects of a frequent apolipoprotein E isoform, ApoE4Freiburg (Leu28-->Pro), on lipoproteins and the prevalence of coronary artery disease in whites.	Arterioscler. Thromb. Vasc. Biol.	19:5:1306-15	1999	10323784		M Orth, W Weng, H Funke, A Steinmetz, G Assmann, M Nauck, J Dierkes, A Ambrosch, K H Weisgraber, R W Mahley, H Wieland, C Luley	M Orth	C Luley	Institut für Klinische Chemie und Pathobiochemie, Universität Magdeburg, Germany.	NHLBI NIH HHS; HL 41633
Mahley RW, Ji ZS	Remnant lipoprotein metabolism: key pathways involving cell-surface heparan sulfate proteoglycans and apolipoprotein E.	J. Lipid Res.	40:1:1-16	1999	9869645		R W Mahley, Z S Ji	R W Mahley	Z S Ji	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL47660
Huang Y, Liu XQ, Rall SC, Taylor JM, von Eckardstein A, Assmann G, Mahley RW	Overexpression and accumulation of apolipoprotein E as a cause of hypertriglyceridemia.	J. Biol. Chem.	273:41:26388-93	1998	9756870		Y Huang, X Q Liu, S C Rall, J M Taylor, A von Eckardstein, G Assmann, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, and Pathology, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL47660
Huang Y, Liu XQ, Rall SC, Mahley RW	Apolipoprotein E2 reduces the low density lipoprotein level in transgenic mice by impairing lipoprotein lipase-mediated lipolysis of triglyceride-rich lipoproteins.	J. Biol. Chem.	273:28:17483-90	1998	9651338		Y Huang, X Q Liu, S C Rall, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL47660
Zhu Y, Bellosta S, Langer C, Bernini F, Pitas RE, Mahley RW, Assmann G, von Eckardstein A	Low-dose expression of a human apolipoprotein E transgene in macrophages restores cholesterol efflux capacity of apolipoprotein E-deficient mouse plasma.	Proc. Natl. Acad. Sci. U.S.A.	95:13:7585-90	1998	9636193		Y Zhu, S Bellosta, C Langer, F Bernini, R E Pitas, R W Mahley, G Assmann, A von Eckardstein	Y Zhu	A von Eckardstein	Institute of Arteriosclerosis Research, Domagkstrasse 3, D-48149 Münster, Germany.	NA
Ji ZS, Pitas RE, Mahley RW	Differential cellular accumulation/retention of apolipoprotein E mediated by cell surface heparan sulfate proteoglycans. Apolipoproteins E3 and E2 greater than e4.	J. Biol. Chem.	273:22:13452-60	1998	9593678		Z S Ji, R E Pitas, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL41633
Fan J, Ji ZS, Huang Y, de Silva H, Sanan D, Mahley RW, Innerarity TL, Taylor JM	Increased expression of apolipoprotein E in transgenic rabbits results in reduced levels of very low density lipoproteins and an accumulation of low density lipoproteins in plasma.	J. Clin. Invest.	101:10:2151-64	1998	9593771		J Fan, Z S Ji, Y Huang, H de Silva, D Sanan, R W Mahley, T L Innerarity, J M Taylor	J Fan	J M Taylor	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141, USA.	NHLBI NIH HHS; HL51588
Pitas RE, Ji ZS, Weisgraber KH, Mahley RW	Role of apolipoprotein E in modulating neurite outgrowth: potential effect of intracellular apolipoprotein E.	Biochem. Soc. Trans.	26:2:257-62	1998	9649758		R E Pitas, Z S Ji, K H Weisgraber, R W Mahley	R E Pitas	R W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL41633
Dichek HL, Brecht W, Fan J, Ji ZS, McCormick SP, Akeefe H, Conzo L, Sanan DA, Weisgraber KH, Young SG, Taylor JM, Mahley RW	Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Evidence that hepatic lipase acts as a ligand for lipoprotein uptake.	J. Biol. Chem.	273:4:1896-903	1998	9442022		H L Dichek, W Brecht, J Fan, Z S Ji, S P McCormick, H Akeefe, L Conzo, D A Sanan, K H Weisgraber, S G Young, J M Taylor, R W Mahley	H L Dichek	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL51588
Ji ZS, Dichek HL, Miranda RD, Mahley RW	Heparan sulfate proteoglycans participate in hepatic lipaseand apolipoprotein E-mediated binding and uptake of plasma lipoproteins, including high density lipoproteins.	J. Biol. Chem.	272:50:31285-92	1997	9395455		Z S Ji, H L Dichek, R D Miranda, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California, 94141-9100, USA.	NHLBI NIH HHS; HL41633
Huang Y, Rall SC, Mahley RW	Genetic factors precipitating type III hyperlipoproteinemia in hypolipidemic transgenic mice expressing human apolipoprotein E2.	Arterioscler. Thromb. Vasc. Biol.	17:11:2817-24	1997	9409260		Y Huang, S C Rall, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, USA.	NHLBI NIH HHS; HL47660
Huang Y, Schwendner SW, Rall SC, Sanan DA, Mahley RW	Apolipoprotein E2 transgenic rabbits. Modulation of the type III hyperlipoproteinemic phenotype by estrogen and occurrence of spontaneous atherosclerosis.	J. Biol. Chem.	272:36:22685-94	1997	9312550		Y Huang, S W Schwendner, S C Rall, D A Sanan, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL47660
Mahley RW	The J. David Gladstone Institutes.	Mol. Med.	3:9:569-71	1997	9323707		R W Mahley	R W Mahley	R W Mahley	J. David Gladstone Institutes, San Francisco, CA 94141-9100, USA. robert_mahley@quickmail.ucsf.edu	NA
Hussain MM, Goldberg IJ, Weisgraber KH, Mahley RW, Innerarity TL	Uptake of chylomicrons by the liver, but not by the bone marrow, is modulated by lipoprotein lipase activity.	Arterioscler. Thromb. Vasc. Biol.	17:7:1407-13	1997	9261274		M M Hussain, I J Goldberg, K H Weisgraber, R W Mahley, T L Innerarity	M M Hussain	T L Innerarity	Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94141-9100, USA.	NHLBI NIH HHS; HL45095
McGeer PL, Walker DG, Pitas RE, Mahley RW, McGeer EG	Apolipoprotein E4 (ApoE4) but not ApoE3 or ApoE2 potentiates beta-amyloid protein activation of complement in vitro.	Brain Res.	749:1:135-8	1997	9070638		P L McGeer, D G Walker, R E Pitas, R W Mahley, E G McGeer	P L McGeer	E G McGeer	Kinsmen Laboratory of Neurological Research, University of British Columbia, Vancouver, Canada. plmcgeer@unixg.ubc.ca	NHLBI NIH HHS; HL41633
Huang Y, Schwendner SW, Rall SC, Mahley RW	Hypolipidemic and hyperlipidemic phenotypes in transgenic mice expressing human apolipoprotein E2.	J. Biol. Chem.	271:46:29146-51	1996	8910571		Y Huang, S W Schwendner, S C Rall, R W Mahley	Y Huang	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL47660
Weisgraber KH, Mahley RW	Human apolipoprotein E: the Alzheimer's disease connection.	FASEB J.	10:13:1485-94	1996	8940294		K H Weisgraber, R W Mahley	K H Weisgraber	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California at San Francisco, 94141-9100, USA.	NHLBI NIH HHS; HL41633
Mahley RW	Heparan sulfate proteoglycan/low density lipoprotein receptor-related protein pathway involved in type III hyperlipoproteinemia and Alzheimer's disease.	Isr. J. Med. Sci.	32:6:414-29	1996	8682647		R W Mahley	R W Mahley	R W Mahley	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL47660
Mahley RW, Nathan BP, Pitas RE	Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease.	Ann. N. Y. Acad. Sci.	777:139-45	1996	8624076		R W Mahley, B P Nathan, R E Pitas	R W Mahley	R E Pitas	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100, USA.	NHLBI NIH HHS; HL41633
Bellosta S, Nathan BP, Orth M, Dong LM, Mahley RW, Pitas RE	Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth.	J. Biol. Chem.	270:45:27063-71	1995	7592957		S Bellosta, B P Nathan, M Orth, L M Dong, R W Mahley, R E Pitas	S Bellosta	R E Pitas	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL41633
Bellosta S, Mahley RW, Sanan DA, Murata J, Newland DL, Taylor JM, Pitas RE	Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice.	J. Clin. Invest.	96:5:2170-9	1995	7593602		S Bellosta, R W Mahley, D A Sanan, J Murata, D L Newland, J M Taylor, R E Pitas	S Bellosta	R E Pitas	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL-47660
Holtzman DM, Pitas RE, Kilbridge J, Nathan B, Mahley RW, Bu G, Schwartz AL	Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line.	Proc. Natl. Acad. Sci. U.S.A.	92:21:9480-4	1995	7568158		D M Holtzman, R E Pitas, J Kilbridge, B Nathan, R W Mahley, G Bu, A L Schwartz	D M Holtzman	A L Schwartz	Department of Neurology, Washington University School of Medicine, St. Louis, MO 63110, USA.	NIA NIH HHS; AG00445
Nathan BP, Chang KC, Bellosta S, Brisch E, Ge N, Mahley RW, Pitas RE	The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization.	J. Biol. Chem.	270:34:19791-9	1995	7649988		B P Nathan, K C Chang, S Bellosta, E Brisch, N Ge, R W Mahley, R E Pitas	B P Nathan	R E Pitas	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL41633
Hussain MM, Innerarity TL, Brecht WJ, Mahley RW	Chylomicron metabolism in normal, cholesterol-fed, and Watanabe heritable hyperlipidemic rabbits. Saturation of the sequestration step of the remnant clearance pathway.	J. Biol. Chem.	270:15:8578-87	1995	7721759		M M Hussain, T L Innerarity, W J Brecht, R W Mahley	M M Hussain	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94110, USA.	NHLBI NIH HHS; HL 41633
Mahley RW, Nathan BP, Bellosta S, Pitas RE	Apolipoprotein E: impact of cytoskeletal stability in neurons and the relationship to Alzheimer's disease.	Curr. Opin. Lipidol.	6:2:86-91	1995	7773573		R W Mahley, B P Nathan, S Bellosta, R E Pitas	R W Mahley	R E Pitas	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California, San Francisco, USA.	NHLBI NIH HHS; HL-41633
Mahley RW, Palaoğlu KE, Atak Z, Dawson-Pepin J, Langlois AM, Cheung V, Onat H, Fulks P, Mahley LL, Vakar F	Turkish Heart Study: lipids, lipoproteins, and apolipoproteins.	J. Lipid Res.	36:4:839-59	1995	7616127		R W Mahley, K E Palaoğlu, Z Atak, J Dawson-Pepin, A M Langlois, V Cheung, H Onat, P Fulks, L L Mahley, F Vakar	R W Mahley	F Vakar	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94141-9100, USA.	NA
Ji ZS, Sanan DA, Mahley RW	Intravenous heparinase inhibits remnant lipoprotein clearance from the plasma and uptake by the liver: in vivo role of heparan sulfate proteoglycans.	J. Lipid Res.	36:3:583-92	1995	7539827		Z S Ji, D A Sanan, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL41633
Ji ZS, Mahley RW	Lactoferrin binding to heparan sulfate proteoglycans and the LDL receptor-related protein. Further evidence supporting the importance of direct binding of remnant lipoproteins to HSPG.	Arterioscler. Thromb.	14:12:2025-31	1994	7526899		Z S Ji, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, CA 94141-9100.	NHLBI NIH HHS; HL41633
Thomas DL, Mahley RW, Badur S, Palaoglu E, Quinn TC	The epidemiology of hepatitis C in Turkey.	Infection	22:6:411-4		7698839		D L Thomas, R W Mahley, S Badur, E Palaoglu, T C Quinn	D L Thomas	T C Quinn	Div. of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21205.	NA
Fazio S, Sanan DA, Lee YL, Ji ZS, Mahley RW, Rall SC	Susceptibility to diet-induced atherosclerosis in transgenic mice expressing a dysfunctional human apolipoprotein E(Arg 112,Cys142).	Arterioscler. Thromb.	14:11:1873-9	1994	7947615		S Fazio, D A Sanan, Y L Lee, Z S Ji, R W Mahley, S C Rall	S Fazio	S C Rall	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco.	NHLBI NIH HHS; HL-47660
Mahley RW, Ji ZS, Brecht WJ, Miranda RD, He D	Role of heparan sulfate proteoglycans and the LDL receptor-related protein in remnant lipoprotein metabolism.	Ann. N. Y. Acad. Sci.	737:39-52	1994	7944147		R W Mahley, Z S Ji, W J Brecht, R D Miranda, D He	R W Mahley	D He	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California at San Francisco 94141-9100.	NHLBI NIH HHS; HL41633
Dong LM, Wilson C, Wardell MR, Simmons T, Mahley RW, Weisgraber KH, Agard DA	Human apolipoprotein E. Role of arginine 61 in mediating the lipoprotein preferences of the E3 and E4 isoforms.	J. Biol. Chem.	269:35:22358-65	1994	8071364		L M Dong, C Wilson, M R Wardell, T Simmons, R W Mahley, K H Weisgraber, D A Agard	L M Dong	D A Agard	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NCRR NIH HHS; RR00083
Fan J, Wang J, Bensadoun A, Lauer SJ, Dang Q, Mahley RW, Taylor JM	Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins.	Proc. Natl. Acad. Sci. U.S.A.	91:18:8724-8	1994	8078949		J Fan, J Wang, A Bensadoun, S J Lauer, Q Dang, R W Mahley, J M Taylor	J Fan	J M Taylor	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, CA 94141.	NHLBI NIH HHS; HL51588
Wilson C, Mau T, Weisgraber KH, Wardell MR, Mahley RW, Agard DA	Salt bridge relay triggers defective LDL receptor binding by a mutant apolipoprotein.	Structure	2:8:713-8	1994	7994571		C Wilson, T Mau, K H Weisgraber, M R Wardell, R W Mahley, D A Agard	C Wilson	D A Agard	Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco 94143-0448.	NCRR NIH HHS; RR-1081
Lüttmann S, von Eckardstein A, Wei W, Funke H, Köhler E, Mahley RW, Assmann G	Electrophoretic screening for genetic variation in apolipoprotein C-III: identification of a novel apoC-III variant, apoC-III(Asp45-->Asn), in a Turkish patient.	J. Lipid Res.	35:8:1431-40	1994	7989867		S Lüttmann, A von Eckardstein, W Wei, H Funke, E Köhler, R W Mahley, G Assmann	S Lüttmann	G Assmann	Laboratoriumsmedizin, Zentrallaboratorium, Westfälische Wilhelms-Universität Münster, Germany.	NA
Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD	Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3.	J. Clin. Invest.	94:2:860-9	1994	8040342		D A Sanan, K H Weisgraber, S J Russell, R W Mahley, D Huang, A Saunders, D Schmechel, T Wisniewski, B Frangione, A D Roses	D A Sanan	A D Roses	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, California 94141-9100.	NIA NIH HHS; 5R15AG07922
de Silva HV, Más-Oliva J, Taylor JM, Mahley RW	Identification of apolipoprotein B-100 low density lipoproteins, apolipoprotein B-48 remnants, and apolipoprotein E-rich high density lipoproteins in the mouse.	J. Lipid Res.	35:7:1297-310	1994	7964191		H V de Silva, J Más-Oliva, J M Taylor, R W Mahley	H V de Silva	R W Mahley	Gladstone Institute of Cardiovascular Disease, Departments of Physiology, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL41633
Ji ZS, Lauer SJ, Fazio S, Bensadoun A, Taylor JM, Mahley RW	Enhanced binding and uptake of remnant lipoproteins by hepatic lipase-secreting hepatoma cells in culture.	J. Biol. Chem.	269:18:13429-36	1994	8175774		Z S Ji, S J Lauer, S Fazio, A Bensadoun, J M Taylor, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, Department of Pathology, San Francisco, California 94141-9100.	NHLBI NIH HHS; HL41633
Ji ZS, Fazio S, Mahley RW	Variable heparan sulfate proteoglycan binding of apolipoprotein E variants may modulate the expression of type III hyperlipoproteinemia.	J. Biol. Chem.	269:18:13421-8	1994	8175773		Z S Ji, S Fazio, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, California 94141-9100.	NHLBI NIH HHS; HL41633
Nathan BP, Bellosta S, Sanan DA, Weisgraber KH, Mahley RW, Pitas RE	Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro.	Science	264:5160:850-2	1994	8171342		B P Nathan, S Bellosta, D A Sanan, K H Weisgraber, R W Mahley, R E Pitas	B P Nathan	R E Pitas	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL 41633
Ji ZS, Fazio S, Lee YL, Mahley RW	Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans.	J. Biol. Chem.	269:4:2764-72	1994	8300609		Z S Ji, S Fazio, Y L Lee, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL41633
de Silva HV, Lauer SJ, Wang J, Simonet WS, Weisgraber KH, Mahley RW, Taylor JM	Overexpression of human apolipoprotein C-III in transgenic mice results in an accumulation of apolipoprotein B48 remnants that is corrected by excess apolipoprotein E.	J. Biol. Chem.	269:3:2324-35	1994	8294490		H V de Silva, S J Lauer, J Wang, W S Simonet, K H Weisgraber, R W Mahley, J M Taylor	H V de Silva	J M Taylor	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL41633
Chiesa G, Johnson DF, Yao Z, Innerarity TL, Mahley RW, Young SG, Hammer RH, Hobbs HH	Expression of human apolipoprotein B100 in transgenic mice. Editing of human apolipoprotein B100 mRNA.	J. Biol. Chem.	268:32:23747-50	1993	8226902		G Chiesa, D F Johnson, Z Yao, T L Innerarity, R W Mahley, S G Young, R H Hammer, H H Hobbs	G Chiesa	H H Hobbs	Department of Molecular Genetics, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas 75235.	NHLBI NIH HHS; HL-47660
Lund-Katz S, Weisgraber KH, Mahley RW, Phillips MC	Conformation of apolipoprotein E in lipoproteins.	J. Biol. Chem.	268:31:23008-15	1993	8226815		S Lund-Katz, K H Weisgraber, R W Mahley, M C Phillips	S Lund-Katz	M C Phillips	Biochemistry Department, Medical College of Pennsylvania, Philadelphia 19129.	NHLBI NIH HHS; HL22633
Thomas DL, Mahley RW, Badur S, Palaoglu KE, Quinn TC	Epidemiology of hepatitis E virus infection in Turkey.	Lancet	341:8860:1561-2	1993	8099641		D L Thomas, R W Mahley, S Badur, K E Palaoglu, T C Quinn	D L Thomas	T C Quinn	Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.	NA
Ji ZS, Brecht WJ, Miranda RD, Hussain MM, Innerarity TL, Mahley RW	Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells.	J. Biol. Chem.	268:14:10160-7	1993	7683668		Z S Ji, W J Brecht, R D Miranda, M M Hussain, T L Innerarity, R W Mahley	Z S Ji	R W Mahley	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94141-9100.	NHLBI NIH HHS; HL41633
de Silva HV, Lauer SJ, Mahley RW, Weisgraber KH, Taylor JM	Apolipoproteins E and C-III have opposing roles in the clearance of lipoprotein remnants in transgenic mice.	Biochem. Soc. Trans.	21:2:483-7	1993	8359515		H V de Silva, S J Lauer, R W Mahley, K H Weisgraber, J M Taylor	H V de Silva	J M Taylor	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL41633
Schmidt EB, Illingworth DR, Bacon S, Russell SJ, Thatcher SR, Mahley RW, Weisgraber KH	Hypolipidemic effects of nicotinic acid in patients with familial defective apolipoprotein B-100.	Metab. Clin. Exp.	42:2:137-9	1993	8474308		E B Schmidt, D R Illingworth, S Bacon, S J Russell, S R Thatcher, R W Mahley, K H Weisgraber	E B Schmidt	K H Weisgraber	Department of Medicine, Oregon Health Sciences University, Portland 97201-3098.	NCRR NIH HHS; RR334
Schmidt EB, Illingworth DR, Bacon S, Mahley RW, Weisgraber KH	Hypocholesterolemic effects of cholestyramine and colestipol in patients with familial defective apolipoprotein B-100.	Atherosclerosis	98:2:213-7	1993	8457260		E B Schmidt, D R Illingworth, S Bacon, R W Mahley, K H Weisgraber	E B Schmidt	K H Weisgraber	Department of Medicine, Oregon Health Sciences University, Portland 97201-3098.	NCRR NIH HHS; RR334
Handelmann GE, Boyles JK, Weisgraber KH, Mahley RW, Pitas RE	Effects of apolipoprotein E, beta-very low density lipoproteins, and cholesterol on the extension of neurites by rabbit dorsal root ganglion neurons in vitro.	J. Lipid Res.	33:11:1677-88	1992	1464751		G E Handelmann, J K Boyles, K H Weisgraber, R W Mahley, R E Pitas	G E Handelmann	R E Pitas	Gladstone Institute of Cardiovascular Disease, Department of Pathology, University of California 94141-9100.	NINDS NIH HHS; NS25678
Rall SC, Mahley RW	The role of apolipoprotein E genetic variants in lipoprotein disorders.	J. Intern. Med.	231:6:653-9	1992	1619388		S C Rall, R W Mahley	S C Rall	R W Mahley	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco.	NA
Illingworth DR, Vakar F, Mahley RW, Weisgraber KH	Hypocholesterolaemic effects of lovastatin in familial defective apolipoprotein B-100.	Lancet	339:8793:598-600	1992	1347103		D R Illingworth, F Vakar, R W Mahley, K H Weisgraber	D R Illingworth	K H Weisgraber	Department of Medicine, Oregon Health Sciences University, Portland 97201-3098.	NA
Hussain MM, Maxfield FR, Más-Oliva J, Tabas I, Ji ZS, Innerarity TL, Mahley RW	Clearance of chylomicron remnants by the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor.	J. Biol. Chem.	266:21:13936-40	1991	1713211		M M Hussain, F R Maxfield, J Más-Oliva, I Tabas, Z S Ji, T L Innerarity, R W Mahley	M M Hussain	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL39303
Wilson C, Wardell MR, Weisgraber KH, Mahley RW, Agard DA	Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E.	Science	252:5014:1817-22	1991	2063194		C Wilson, M R Wardell, K H Weisgraber, R W Mahley, D A Agard	C Wilson	D A Agard	Howard Hughes Medical Institute, University of California, San Francisco 94143-0448.	NHLBI NIH HHS; HL-41633
Mahley RW, Weisgraber KH, Innerarity TL, Rall SC	Genetic defects in lipoprotein metabolism. Elevation of atherogenic lipoproteins caused by impaired catabolism.	JAMA	265:1:78-83	1991	1845776		R W Mahley, K H Weisgraber, T L Innerarity, S C Rall	R W Mahley	S C Rall	Gladstone Foundation Laboratories for Cardiovascular Disease, Cardiovascular Research Institute, San Francisco, CA 94140.	NHLBI NIH HHS; HL41633
Weisgraber KH, Mahley RW, Kowal RC, Herz J, Goldstein JL, Brown MS	Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.	J. Biol. Chem.	265:36:22453-9	1990	2266137		K H Weisgraber, R W Mahley, R C Kowal, J Herz, J L Goldstein, M S Brown	K H Weisgraber	M S Brown	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL41633
Crook D, Weisgraber KH, Rall SC, Mahley RW	Isolation and characterization of several plasma apolipoproteins of common marmoset monkey.	Arteriosclerosis	10:4:625-32		2114867		D Crook, K H Weisgraber, S C Rall, R W Mahley	D Crook	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140.	NA
Crook D, Weisgraber KH, Boyles JK, Mahley RW	Isolation and characterization of plasma lipoproteins of common marmoset monkey. Comparison of effects of control and atherogenic diets.	Arteriosclerosis	10:4:633-47		2114868		D Crook, K H Weisgraber, J K Boyles, R W Mahley	D Crook	R W Mahley	Gladstone Foundation Laboratoreis for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140.	NA
Kowal RC, Herz J, Weisgraber KH, Mahley RW, Brown MS, Goldstein JL	Opposing effects of apolipoproteins E and C on lipoprotein binding to low density lipoprotein receptor-related protein.	J. Biol. Chem.	265:18:10771-9	1990	2355022		R C Kowal, J Herz, K H Weisgraber, R W Mahley, M S Brown, J L Goldstein	R C Kowal	J L Goldstein	Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235.	NHLBI NIH HHS; HL 41633
Weisgraber KH, Innerarity TL, Rall SC, Mahley RW	Atherogenic lipoproteins resulting from genetic defects of apolipoproteins B and E.	Ann. N. Y. Acad. Sci.	598:37-48	1990	2248450		K H Weisgraber, T L Innerarity, S C Rall, R W Mahley	K H Weisgraber	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NA
Hussain MM, Mahley RW, Boyles JK, Lindquist PA, Brecht WJ, Innerarity TL	Chylomicron metabolism. Chylomicron uptake by bone marrow in different animal species.	J. Biol. Chem.	264:30:17931-8	1989	2509449		M M Hussain, R W Mahley, J K Boyles, P A Lindquist, W J Brecht, T L Innerarity	M M Hussain	T L Innerarity	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NA
Steinberg D, Carew TE, Fielding C, Fogelman AM, Mahley RW, Sniderman AD, Zilversmit DB	Lipoproteins and the pathogenesis of atherosclerosis.	Circulation	80:3:719-23	1989	2670321		D Steinberg, T E Carew, C Fielding, A M Fogelman, R W Mahley, A D Sniderman, D B Zilversmit	D Steinberg	D B Zilversmit		NA
Hussain MM, Mahley RW, Boyles JK, Fainaru M, Brecht WJ, Lindquist PA	Chylomicron-chylomicron remnant clearance by liver and bone marrow in rabbits. Factors that modify tissue-specific uptake.	J. Biol. Chem.	264:16:9571-82	1989	2722852		M M Hussain, R W Mahley, J K Boyles, M Fainaru, W J Brecht, P A Lindquist	M M Hussain	P A Lindquist	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL 28178
Mahley RW, Weisgraber KH, Hussain MM, Greenman B, Fisher M, Vogel T, Gorecki M	Intravenous infusion of apolipoprotein E accelerates clearance of plasma lipoproteins in rabbits.	J. Clin. Invest.	83:6:2125-30	1989	2723074		R W Mahley, K H Weisgraber, M M Hussain, B Greenman, M Fisher, T Vogel, M Gorecki	R W Mahley	M Gorecki	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140.	NHLBI NIH HHS; HL-28178
Lalazar A, Mahley RW	Human apolipoprotein E. Receptor binding activity of truncated variants with carboxyl-terminal deletions.	J. Biol. Chem.	264:15:8447-50	1989	2542277		A Lalazar, R W Mahley	A Lalazar	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NA
Boyles JK, Zoellner CD, Anderson LJ, Kosik LM, Pitas RE, Weisgraber KH, Hui DY, Mahley RW, Gebicke-Haerter PJ, Ignatius MJ	A role for apolipoprotein E, apolipoprotein A-I, and low density lipoprotein receptors in cholesterol transport during regeneration and remyelination of the rat sciatic nerve.	J. Clin. Invest.	83:3:1015-31	1989	2493483		J K Boyles, C D Zoellner, L J Anderson, L M Kosik, R E Pitas, K H Weisgraber, D Y Hui, R W Mahley, P J Gebicke-Haerter, M J Ignatius	J K Boyles	M J Ignatius	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NA
Weisgraber KH, Newhouse YM, Taylor JM, Tuan B, Nestruck AC, Davignon J, Mahley RW	Apolipoprotein E2(Arg158----Cys) frequency in a hyperlipidemic French-Canadian population of apolipoprotein E2/2 subjects. Determination by synthetic oligonucleotide probes.	Arteriosclerosis	9:1:50-7		2912421		K H Weisgraber, Y M Newhouse, J M Taylor, B Tuan, A C Nestruck, J Davignon, R W Mahley	K H Weisgraber	R W Mahley	Gladstone Foundation Laboratories, University of California, San Francisco, CA 94140.	NA
Mahley RW, Hui DY, Innerarity TL, Beisiegel U	Chylomicron remnant metabolism. Role of hepatic lipoprotein receptors in mediating uptake.	Arteriosclerosis	9:1 Suppl:I14-8		2536272		R W Mahley, D Y Hui, T L Innerarity, U Beisiegel	R W Mahley	U Beisiegel	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140.	NA
Weisgraber KH, Newhouse YM, Mahley RW	Apolipoprotein E genotyping using the polymerase chain reaction and allele-specific oligonucleotide probes.	Biochem. Biophys. Res. Commun.	157:3:1212-7	1988	3207421		K H Weisgraber, Y M Newhouse, R W Mahley	K H Weisgraber	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NA
Weisgraber KH, Innerarity TL, Newhouse YM, Young SG, Arnold KS, Krauss RM, Vega GL, Grundy SM, Mahley RW	Familial defective apolipoprotein B-100: enhanced binding of monoclonal antibody MB47 to abnormal low density lipoproteins.	Proc. Natl. Acad. Sci. U.S.A.	85:24:9758-62	1988	3200853		K H Weisgraber, T L Innerarity, Y M Newhouse, S G Young, K S Arnold, R M Krauss, G L Vega, S M Grundy, R W Mahley	K H Weisgraber	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL 36701
Majack RA, Castle CK, Goodman LV, Weisgraber KH, Mahley RW, Shooter EM, Gebicke-Haerter PJ	Expression of apolipoprotein E by cultured vascular smooth muscle cells is controlled by growth state.	J. Cell Biol.	107:3:1207-13	1988	2458361		R A Majack, C K Castle, L V Goodman, K H Weisgraber, R W Mahley, E M Shooter, P J Gebicke-Haerter	R A Majack	P J Gebicke-Haerter	Atherosclerosis and Thrombosis Research, Upjohn Company, Kalamazoo, Michigan 49001.	NA
Aggerbeck LP, Wetterau JR, Weisgraber KH, Mahley RW, Agard DA	Crystallization and preliminary X-ray diffraction studies on the amino-terminal (receptor-binding) domain of human apolipoprotein E3 from serum very low density lipoproteins.	J. Mol. Biol.	202:1:179-81	1988	3172212		L P Aggerbeck, J R Wetterau, K H Weisgraber, R W Mahley, D A Agard	L P Aggerbeck	D A Agard	Centre de Génétique Moléculaire, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.	NHLBI NIH HHS; HL 18577-11
Koo C, Wernette-Hammond ME, Garcia Z, Malloy MJ, Uauy R, East C, Bilheimer DW, Mahley RW, Innerarity TL	Uptake of cholesterol-rich remnant lipoproteins by human monocyte-derived macrophages is mediated by low density lipoprotein receptors.	J. Clin. Invest.	81:5:1332-40	1988	3163347		C Koo, M E Wernette-Hammond, Z Garcia, M J Malloy, R Uauy, C East, D W Bilheimer, R W Mahley, T L Innerarity	C Koo	T L Innerarity	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NA
Beisiegel U, Weber W, Havinga JR, Ihrke G, Hui DY, Wernette-Hammond ME, Turck CW, Innerarity TL, Mahley RW	Apolipoprotein E-binding proteins isolated from dog and human liver.	Arteriosclerosis	8:3:288-97		2835955		U Beisiegel, W Weber, J R Havinga, G Ihrke, D Y Hui, M E Wernette-Hammond, C W Turck, T L Innerarity, R W Mahley	U Beisiegel	R W Mahley	Medizinische Kernklinik and Poliklinik, Universitätskrankenhaus Eppendorf, Hamburg, Federal Republic of Germany.	NHLBI NIH HHS; HL 28178
Mahley RW	Apolipoprotein E: cholesterol transport protein with expanding role in cell biology.	Science	240:4852:622-30	1988	3283935		R W Mahley	R W Mahley	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NA
Lalazar A, Weisgraber KH, Rall SC, Giladi H, Innerarity TL, Levanon AZ, Boyles JK, Amit B, Gorecki M, Mahley RW	Site-specific mutagenesis of human apolipoprotein E. Receptor binding activity of variants with single amino acid substitutions.	J. Biol. Chem.	263:8:3542-5	1988	2831187		A Lalazar, K H Weisgraber, S C Rall, H Giladi, T L Innerarity, A Z Levanon, J K Boyles, B Amit, M Gorecki, R W Mahley	A Lalazar	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NA
Fainaru M, Funke H, Boyles JK, Ludwig EH, Innerarity TL, Mahley RW	Metabolism of canine beta-very low density lipoproteins in normal and cholesterol-fed dogs.	Arteriosclerosis	8:2:130-9		2831863		M Fainaru, H Funke, J K Boyles, E H Ludwig, T L Innerarity, R W Mahley	M Fainaru	R W Mahley	Department of Pathology, University of California, San Francisco.	NA
Corsini A, Spilman CH, Innerarity TL, Arnold KS, Rall SC, Boyles JK, Mahley RW	Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments.	J. Lipid Res.	28:12:1410-23	1987	2828500		A Corsini, C H Spilman, T L Innerarity, K S Arnold, S C Rall, J K Boyles, R W Mahley	A Corsini	R W Mahley	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL36701
Innerarity TL, Young SG, Poksay KS, Mahley RW, Smith RS, Milne RW, Marcel YL, Weisgraber KH	Structural relationship of human apolipoprotein B48 to apolipoprotein B100.	J. Clin. Invest.	80:6:1794-8	1987	3680528		T L Innerarity, S G Young, K S Poksay, R W Mahley, R S Smith, R W Milne, Y L Marcel, K H Weisgraber	T L Innerarity	K H Weisgraber	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Pathology, University of California, San Francisco 94140.	NHLBI NIH HHS; HL-36701
Friedman G, Wernette-Hammond ME, Hui DY, Mahley RW, Innerarity TL	Characterization of lipoprotein receptors on rat Fu5AH hepatoma cells.	J. Lipid Res.	28:12:1482-94	1987	2828502		G Friedman, M E Wernette-Hammond, D Y Hui, R W Mahley, T L Innerarity	G Friedman	T L Innerarity	Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Medicine, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL28178-02
Innerarity TL, Weisgraber KH, Arnold KS, Mahley RW, Krauss RM, Vega GL, Grundy SM	Familial defective apolipoprotein B-100: low density lipoproteins with abnormal receptor binding.	Proc. Natl. Acad. Sci. U.S.A.	84:19:6919-23	1987	3477815		T L Innerarity, K H Weisgraber, K S Arnold, R W Mahley, R M Krauss, G L Vega, S M Grundy	T L Innerarity	S M Grundy	Gladstone Foundation Laboratories for Cardiovascular Disease, University of California, San Francisco 94140-0608.	NHLBI NIH HHS; HL36701
Ludwig EH, Blackhart BD, Pierotti VR, Caiati L, Fortier C, Knott T, Scott J, Mahley RW, Levy-Wilson B, McCarthy BJ	DNA sequence of the human apolipoprotein B gene.	DNA	6:4:363-72	1987	3652907		E H Ludwig, B D Blackhart, V R Pierotti, L Caiati, C Fortier, T Knott, J Scott, R W Mahley, B Levy-Wilson, B J McCarthy	E H Ludwig	B J McCarthy	Gladstone Foundation Laboratories, Cardiovascular Research Institute, San Francisco, CA 94140.	NCRR NIH HHS; 441-RR-165850-3
Ignatius MJ, Shooter EM, Pitas RE, Mahley RW	Lipoprotein uptake by neuronal growth cones in vitro.	Science	236:4804:959-62	1987	3576212		M J Ignatius, E M Shooter, R E Pitas, R W Mahley	M J Ignatius	R W Mahley		NINDS NIH HHS; NS 04270
Scott J, Pease RJ, Powell LM, Wallis SC, McCarthy BJ, Mahley RW, Levy-Wilson B, Knott TJ	Human apolipoprotein B: complete cDNA sequence and identification of structural domains of the protein.	Biochem. Soc. Trans.	15:2:195-9	1987	3556259		J Scott, R J Pease, L M Powell, S C Wallis, B J McCarthy, R W Mahley, B Levy-Wilson, T J Knott	J Scott	T J Knott		NA
Marcel YL, Innerarity TL, Spilman C, Mahley RW, Protter AA, Milne RW	Mapping of human apolipoprotein B antigenic determinants.	Arteriosclerosis	7:2:166-75		2437897		Y L Marcel, T L Innerarity, C Spilman, R W Mahley, A A Protter, R W Milne	Y L Marcel	R W Milne		NA
Gebicke-Haerter PJ, Darby JK, Shooter EM, Riccardi VM, Weisgraber KH, Boyles JK, Mahley RW	Apolipoprotein E synthesis in neurofibrosarcoma and schwannoma cell cultures from two individuals with neurofibromatosis.	Exp. Neurol.	95:2:323-35	1987	3100319		P J Gebicke-Haerter, J K Darby, E M Shooter, V M Riccardi, K H Weisgraber, J K Boyles, R W Mahley	P J Gebicke-Haerter	R W Mahley		NINDS NIH HHS; NS 04270
Pitas RE, Boyles JK, Lee SH, Foss D, Mahley RW	Astrocytes synthesize apolipoprotein E and metabolize apolipoprotein E-containing lipoproteins.	Biochim. Biophys. Acta	917:1:148-61	1987	3539206		R E Pitas, J K Boyles, S H Lee, D Foss, R W Mahley	R E Pitas	R W Mahley		NA
Scott J, Pease RJ, Powell LM, Wallis SC, McCarthy BJ, Mahley RW, Levy-Wilson B, Knott TJ	Apolipoprotein B gene: plasma cholesterol and atherosclerosis.	Biochem. Soc. Symp.	53:155-63	1987	3332766		J Scott, R J Pease, L M Powell, S C Wallis, B J McCarthy, R W Mahley, B Levy-Wilson, T J Knott	J Scott	T J Knott	Molecular Medicine Research Group, MRC Clinical Research Centre, Harrow, U.K.	NA
Innerarity TL, Weisgraber KH, Rall SC, Mahley RW	Functional domains of apolipoprotein E and apolipoprotein B.	Acta Med. Scand. Suppl.	715:51-9	1987	3035881		T L Innerarity, K H Weisgraber, S C Rall, R W Mahley	T L Innerarity	R W Mahley		NA
Mahley RW	The molecular basis of atherosclerosis: concepts derived from studies of lipoprotein metabolism and cell biology.	Clin Invest Med	9:4:304-8	1986	3026707		R W Mahley	R W Mahley	R W Mahley		NA
Knott TJ, Wallis SC, Powell LM, Pease RJ, Lusis AJ, Blackhart B, McCarthy BJ, Mahley RW, Levy-Wilson B, Scott J	Complete cDNA and derived protein sequence of human apolipoprotein B-100.	Nucleic Acids Res.	14:18:7501-3	1986	3763409		T J Knott, S C Wallis, L M Powell, R J Pease, A J Lusis, B Blackhart, B J McCarthy, R W Mahley, B Levy-Wilson, J Scott	T J Knott	J Scott		NA
Mahley RW, Innerarity TL, Hui DY, Weisgraber KH, Pitas RE	Pathology: plasma cholesterol levels determined by lipoprotein interactions with cell surface receptors.	West. J. Med.	145:3:372	1986	18750070		R W Mahley, T L Innerarity, D Y Hui, K H Weisgraber, R E Pitas	R W Mahley	R E Pitas		NA
Reardon CA, Lau YF, Paik YK, Weisgraber KH, Mahley RW, Taylor JM	Expression of the human apolipoprotein E gene in cultured mammalian cells.	J. Biol. Chem.	261:21:9858-64	1986	3733697		C A Reardon, Y F Lau, Y K Paik, K H Weisgraber, R W Mahley, J M Taylor	C A Reardon	J M Taylor		NA
Rall SC, Weisgraber KH, Mahley RW, Ehnholm C, Schamaun O, Olaisen B, Blomhoff JP, Teisberg P	Identification of homozygosity for a human apolipoprotein A-I variant.	J. Lipid Res.	27:4:436-41	1986	3723016		S C Rall, K H Weisgraber, R W Mahley, C Ehnholm, O Schamaun, B Olaisen, J P Blomhoff, P Teisberg	S C Rall	P Teisberg		NHLBI NIH HHS; HL 27455
Hui DY, Brecht WJ, Hall EA, Friedman G, Innerarity TL, Mahley RW	Isolation and characterization of the apolipoprotein E receptor from canine and human liver.	J. Biol. Chem.	261:9:4256-67	1986	3005328		D Y Hui, W J Brecht, E A Hall, G Friedman, T L Innerarity, R W Mahley	D Y Hui	R W Mahley		NCRR NIH HHS; S07RR05880
Weisgraber KH, Rall SC, Mahley RW, Milne RW, Marcel YL, Sparrow JT	Human apolipoprotein E. Determination of the heparin binding sites of apolipoprotein E3.	J. Biol. Chem.	261:5:2068-76	1986	2418019		K H Weisgraber, S C Rall, R W Mahley, R W Milne, Y L Marcel, J T Sparrow	K H Weisgraber	J T Sparrow		NHLBI NIH HHS; HL30064
Ignatius MJ, Gebicke-Härter PJ, Skene JH, Schilling JW, Weisgraber KH, Mahley RW, Shooter EM	Expression of apolipoprotein E during nerve degeneration and regeneration.	Proc. Natl. Acad. Sci. U.S.A.	83:4:1125-9	1986	2419900		M J Ignatius, P J Gebicke-Härter, J H Skene, J W Schilling, K H Weisgraber, R W Mahley, E M Shooter	M J Ignatius	E M Shooter		NINDS NIH HHS; NS 20178
Taylor JM, Mahley RW, Fukazawa C	Cloning of the cDNA for rat and human apolipoprotein E mRNA.	Meth. Enzymol.	128:801-11	1986	2425224		J M Taylor, R W Mahley, C Fukazawa	J M Taylor	C Fukazawa		NA
Weisgraber KH, Mahley RW	Characterization of apolipoprotein E-containing lipoproteins.	Meth. Enzymol.	129:145-66	1986	3724537		K H Weisgraber, R W Mahley	K H Weisgraber	R W Mahley		NA
Innerarity TL, Pitas RE, Mahley RW	Lipoprotein-receptor interactions.	Meth. Enzymol.	129:542-65	1986	2425225		T L Innerarity, R E Pitas, R W Mahley	T L Innerarity	R W Mahley		NA
Rall SC, Weisgraber KH, Mahley RW	Isolation and characterization of apolipoprotein E.	Meth. Enzymol.	128:273-87	1986	3724506		S C Rall, K H Weisgraber, R W Mahley	S C Rall	R W Mahley		NA
Mahley RW, Innerarity TL, Weisgraber KH, Rall SC, Hui DY, Lalazar A, Boyles JK, Taylor JM, Levy-Wilson B	Cellular and molecular biology of lipoprotein metabolism: characterization of lipoprotein receptor-ligand interactions.	Cold Spring Harb. Symp. Quant. Biol.	51 Pt 2:821-8	1986	3034497		R W Mahley, T L Innerarity, K H Weisgraber, S C Rall, D Y Hui, A Lalazar, J K Boyles, J M Taylor, B Levy-Wilson	R W Mahley	B Levy-Wilson		NA
Innerarity TL, Arnold KS, Weisgraber KH, Mahley RW	Apolipoprotein E is the determinant that mediates the receptor uptake of beta-very low density lipoproteins by mouse macrophages.	Arteriosclerosis	6:1:114-22		3942555		T L Innerarity, K S Arnold, K H Weisgraber, R W Mahley	T L Innerarity	R W Mahley		NA
Reardon CA, Paik YK, Chang DJ, Davies GE, Mahley RW, Lau YF, Taylor JM	Cloning and expression of the human apolipoprotein E gene.	Meth. Enzymol.	128:811-23	1986	3014273		C A Reardon, Y K Paik, D J Chang, G E Davies, R W Mahley, Y F Lau, J M Taylor	C A Reardon	J M Taylor		NA
Weisgraber KH, Newhouse YM, Seymour JL, Rall SC, Mahley RW	Preparative immobiline isoelectric focusing of plasma apolipoproteins on vertical slab gels.	Anal. Biochem.	151:2:455-61	1985	4096384		K H Weisgraber, Y M Newhouse, J L Seymour, S C Rall, R W Mahley	K H Weisgraber	R W Mahley		NA
Mahley RW	Atherogenic lipoproteins and coronary artery disease: concepts derived from recent advances in cellular and molecular biology.	Circulation	72:5:943-8	1985	4042302		R W Mahley	R W Mahley	R W Mahley		NA
Koo C, Innerarity TL, Mahley RW	Obligatory role of cholesterol and apolipoprotein E in the formation of large cholesterol-enriched and receptor-active high density lipoproteins.	J. Biol. Chem.	260:22:11934-43	1985	2995353		C Koo, T L Innerarity, R W Mahley	C Koo	R W Mahley		NA
Boyles JK, Pitas RE, Wilson E, Mahley RW, Taylor JM	Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system.	J. Clin. Invest.	76:4:1501-13	1985	3932467		J K Boyles, R E Pitas, E Wilson, R W Mahley, J M Taylor	J K Boyles	J M Taylor		NA
Cornhill JF, Barrett WA, Herderick EE, Mahley RW, Fry DL	Topographic study of sudanophilic lesions in cholesterol-fed minipigs by image analysis.	Arteriosclerosis	5:5:415-26		2412537		J F Cornhill, W A Barrett, E E Herderick, R W Mahley, D L Fry	J F Cornhill	D L Fry		NA
Weisgraber KH, Innerarity TL, Rall SC, Mahley RW	Receptor interactions controlling lipoprotein metabolism.	Can. J. Biochem. Cell Biol.	63:8:898-905	1985	2998579		K H Weisgraber, T L Innerarity, S C Rall, R W Mahley	K H Weisgraber	R W Mahley		NA
Paik YK, Chang DJ, Reardon CA, Davies GE, Mahley RW, Taylor JM	Nucleotide sequence and structure of the human apolipoprotein E gene.	Proc. Natl. Acad. Sci. U.S.A.	82:10:3445-9	1985	2987927		Y K Paik, D J Chang, C A Reardon, G E Davies, R W Mahley, J M Taylor	Y K Paik	J M Taylor		NA
Weisgraber KH, Innerarity TL, Rall SC, Mahley RW	Apolipoprotein E: receptor binding properties.	Adv. Exp. Med. Biol.	183:159-71	1985	2412412		K H Weisgraber, T L Innerarity, S C Rall, R W Mahley	K H Weisgraber	R W Mahley		NA
Elshourbagy NA, Liao WS, Mahley RW, Taylor JM	Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets.	Proc. Natl. Acad. Sci. U.S.A.	82:1:203-7	1985	3918303		N A Elshourbagy, W S Liao, R W Mahley, J M Taylor	N A Elshourbagy	J M Taylor		NA
Mahley RW, Innerarity TL, Rall SC, Weisgraber KH	Lipoproteins of special significance in atherosclerosis. Insights provided by studies of type III hyperlipoproteinemia.	Ann. N. Y. Acad. Sci.	454:209-21	1985	3000263		R W Mahley, T L Innerarity, S C Rall, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Pitas RE, Boyles J, Mahley RW, Bissell DM	Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells.	J. Cell Biol.	100:1:103-17	1985	3965468		R E Pitas, J Boyles, R W Mahley, D M Bissell	R E Pitas	D M Bissell		NA
Hui DY, Innerarity TL, Milne RW, Marcel YL, Mahley RW	Binding of chylomicron remnants and beta-very low density lipoproteins to hepatic and extrahepatic lipoprotein receptors. A process independent of apolipoprotein B48.	J. Biol. Chem.	259:24:15060-8	1984	6096356		D Y Hui, T L Innerarity, R W Milne, Y L Marcel, R W Mahley	D Y Hui	R W Mahley		NHLBI NIH HHS; HL28178-02
Mahley RW, Innerarity TL, Rall SC, Weisgraber KH	Plasma lipoproteins: apolipoprotein structure and function.	J. Lipid Res.	25:12:1277-94	1984	6099394		R W Mahley, T L Innerarity, S C Rall, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Utermann G, Haas J, Steinmetz A, Paetzold R, Rall SC, Weisgraber KH, Mahley RW	Apolipoprotein A-IGiessen (Pro143----Arg). A mutant that is defective in activating lecithin:cholesterol acyltransferase.	Eur. J. Biochem.	144:2:325-31	1984	6489332		G Utermann, J Haas, A Steinmetz, R Paetzold, S C Rall, K H Weisgraber, R W Mahley	G Utermann	R W Mahley		NHLBI NIH HHS; HL 27455
Ehnholm C, Mahley RW, Chappell DA, Weisgraber KH, Ludwig E, Witztum JL	Role of apolipoprotein E in the lipolytic conversion of beta-very low density lipoproteins to low density lipoproteins in type III hyperlipoproteinemia.	Proc. Natl. Acad. Sci. U.S.A.	81:17:5566-70	1984	6591204		C Ehnholm, R W Mahley, D A Chappell, K H Weisgraber, E Ludwig, J L Witztum	C Ehnholm	J L Witztum		NIADDK NIH HHS; AM07418
Funke H, Boyles J, Weisgraber KH, Ludwig EH, Hui DY, Mahley RW	Uptake of apolipoprotein E-containing high density lipoproteins by hepatic parenchymal cells.	Arteriosclerosis	4:5:452-61		6089725		H Funke, J Boyles, K H Weisgraber, E H Ludwig, D Y Hui, R W Mahley	H Funke	R W Mahley		NA
Rall SC, Weisgraber KH, Mahley RW, Ogawa Y, Fielding CJ, Utermann G, Haas J, Steinmetz A, Menzel HJ, Assmann G	Abnormal lecithin:cholesterol acyltransferase activation by a human apolipoprotein A-I variant in which a single lysine residue is deleted.	J. Biol. Chem.	259:16:10063-70	1984	6432779		S C Rall, K H Weisgraber, R W Mahley, Y Ogawa, C J Fielding, G Utermann, J Haas, A Steinmetz, H J Menzel, G Assmann	S C Rall	G Assmann		NHLBI NIH HHS; HL27455
Innerarity TL, Weisgraber KH, Arnold KS, Rall SC, Mahley RW	Normalization of receptor binding of apolipoprotein E2. Evidence for modulation of the binding site conformation.	J. Biol. Chem.	259:11:7261-7	1984	6327714		T L Innerarity, K H Weisgraber, K S Arnold, S C Rall, R W Mahley	T L Innerarity	R W Mahley		NA
McLean JW, Elshourbagy NA, Chang DJ, Mahley RW, Taylor JM	Human apolipoprotein E mRNA. cDNA cloning and nucleotide sequencing of a new variant.	J. Biol. Chem.	259:10:6498-504	1984	6327682		J W McLean, N A Elshourbagy, D J Chang, R W Mahley, J M Taylor	J W McLean	J M Taylor		NCI NIH HHS; CA00872
Utermann G, Weisgraber KH, Weber W, Mahley RW	Genetic polymorphism of apolipoprotein E: a variant form of apolipoprotein E2 distinguished by sodium dodecyl sulfate--polyacrylamide gel electrophoresis.	J. Lipid Res.	25:4:378-82	1984	6726088		G Utermann, K H Weisgraber, W Weber, R W Mahley	G Utermann	R W Mahley		NA
Weisgraber KH, Rall SC, Innerarity TL, Mahley RW, Kuusi T, Ehnholm C	A novel electrophoretic variant of human apolipoprotein E. Identification and characterization of apolipoprotein E1.	J. Clin. Invest.	73:4:1024-33	1984	6323533		K H Weisgraber, S C Rall, T L Innerarity, R W Mahley, T Kuusi, C Ehnholm	K H Weisgraber	C Ehnholm		NA
Menzel HJ, Assmann G, Rall SC, Weisgraber KH, Mahley RW	Human apolipoprotein A-I polymorphism. Identification of amino acid substitutions in three electrophoretic variants of the Münster-3 type.	J. Biol. Chem.	259:5:3070-6	1984	6421816		H J Menzel, G Assmann, S C Rall, K H Weisgraber, R W Mahley	H J Menzel	R W Mahley		NHLBI NIH HHS; HL27455
Hui DY, Innerarity TL, Mahley RW	Defective hepatic lipoprotein receptor binding of beta-very low density lipoproteins from type III hyperlipoproteinemic patients. Importance of apolipoprotein E.	J. Biol. Chem.	259:2:860-9	1984	6319389		D Y Hui, T L Innerarity, R W Mahley	D Y Hui	R W Mahley		NHLBI NIH HHS; HL28178-02
Steinmetz A, Utermann G, Haas J, Menzel HJ, Rall SC, Weisgraber KH, Mahley RW	Mutations of apolipoprotein AI can affect cofactor function for cholesteryl ester formation by lecithin: cholesterol acyltransferase.	Agents Actions Suppl.	16:217-24	1984	6435410		A Steinmetz, G Utermann, J Haas, H J Menzel, S C Rall, K H Weisgraber, R W Mahley	A Steinmetz	R W Mahley		NA
Mahley RW, Angelin B	Type III hyperlipoproteinemia: recent insights into the genetic defect of familial dysbetalipoproteinemia.	Adv Intern Med	29:385-411	1984	6369930		R W Mahley, B Angelin	R W Mahley	B Angelin		NA
Weisgraber KH, Innerarity TL, Harder KJ, Mahley RW, Milne RW, Marcel YL, Sparrow JT	The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding.	J. Biol. Chem.	258:20:12348-54	1983	6313653		K H Weisgraber, T L Innerarity, K J Harder, R W Mahley, R W Milne, Y L Marcel, J T Sparrow	K H Weisgraber	J T Sparrow		NHLBI NIH HHS; HL30064
Innerarity TL, Friedlander EJ, Rall SC, Weisgraber KH, Mahley RW	The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments.	J. Biol. Chem.	258:20:12341-7	1983	6313652		T L Innerarity, E J Friedlander, S C Rall, K H Weisgraber, R W Mahley	T L Innerarity	R W Mahley		NA
Schmitz G, Assmann G, Rall SC, Mahley RW	Tangier disease: defective recombination of a specific Tangier apolipoprotein A-I isoform (pro-apo A-i) with high density lipoproteins.	Proc. Natl. Acad. Sci. U.S.A.	80:19:6081-5	1983	6412234		G Schmitz, G Assmann, S C Rall, R W Mahley	G Schmitz	R W Mahley		NHLBI NIH HHS; HL27455
Mahley RW	Development of accelerated atherosclerosis. Concepts derived from cell biology and animal model studies.	Arch. Pathol. Lab. Med.	107:8:393-9	1983	6307210		R W Mahley	R W Mahley	R W Mahley		NA
Rouleau JL, Parmley WW, Stevens J, Wikman-Coffelt J, Sievers R, Mahley RW, Havel RJ	Verapamil suppresses atherosclerosis in cholesterol-fed rabbits.	J. Am. Coll. Cardiol.	1:6:1453-60	1983	6304174		J L Rouleau, W W Parmley, J Stevens, J Wikman-Coffelt, R Sievers, R W Mahley, R J Havel	J L Rouleau	R J Havel		NHLBI NIH HHS; HL-14237
Gordon V, Innerarity TL, Mahley RW	Formation of cholesterol- and apoprotein E-enriched high density lipoproteins in vitro.	J. Biol. Chem.	258:10:6202-12	1983	6343371		V Gordon, T L Innerarity, R W Mahley	V Gordon	R W Mahley		NA
Mahley RW, Innerarity TL	Lipoprotein receptors and cholesterol homeostasis.	Biochim. Biophys. Acta	737:2:197-222	1983	6303423		R W Mahley, T L Innerarity	R W Mahley	T L Innerarity		NA
Rall SC, Weisgraber KH, Innerarity TL, Mahley RW	Identical structural and receptor binding defects in apolipoprotein E2 in hypo-, normo-, and hypercholesterolemic dysbetalipoproteinemia.	J. Clin. Invest.	71:4:1023-31	1983	6300187		S C Rall, K H Weisgraber, T L Innerarity, R W Mahley	S C Rall	R W Mahley		NA
Angelin B, Raviola CA, Innerarity TL, Mahley RW	Regulation of hepatic lipoprotein receptors in the dog. Rapid regulation of apolipoprotein B,E receptors, but not of apolipoprotein E receptors, by intestinal lipoproteins and bile acids.	J. Clin. Invest.	71:4:816-31	1983	6300188		B Angelin, C A Raviola, T L Innerarity, R W Mahley	B Angelin	R W Mahley		NA
Mahley RW	Apolipoprotein E and cholesterol metabolism.	Klin. Wochenschr.	61:5:225-32	1983	6843048		R W Mahley	R W Mahley	R W Mahley		NA
Pitas RE, Innerarity TL, Mahley RW	Foam cells in explants of atherosclerotic rabbit aortas have receptors for beta-very low density lipoproteins and modified low density lipoproteins.	Arteriosclerosis	3:1:2-12		6297442		R E Pitas, T L Innerarity, R W Mahley	R E Pitas	R W Mahley		NA
Rall SC, Weisgraber KH, Innerarity TL, Mahley RW	Structural basis for receptor binding heterogeneity of apolipoprotein E from type III hyperlipoproteinemic subjects.	Proc. Natl. Acad. Sci. U.S.A.	79:15:4696-700	1982	6289314		S C Rall, K H Weisgraber, T L Innerarity, R W Mahley	S C Rall	R W Mahley		NA
Zannis VI, Breslow JL, Utermann G, Mahley RW, Weisgraber KH, Havel RJ, Goldstein JL, Brown MS, Schonfeld G, Hazzard WR, Blum C	Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes.	J. Lipid Res.	23:6:911-4	1982	7130859		V I Zannis, J L Breslow, G Utermann, R W Mahley, K H Weisgraber, R J Havel, J L Goldstein, M S Brown, G Schonfeld, W R Hazzard, C Blum	V I Zannis	C Blum		NA
Fainaru M, Mahley RW, Hamilton RL, Innerarity TL	Structural and metabolic heterogeneity of beta-very low density lipoproteins from cholesterol-fed dogs and from humans with type III hyperlipoproteinemia.	J. Lipid Res.	23:5:702-14	1982	7119569		M Fainaru, R W Mahley, R L Hamilton, T L Innerarity	M Fainaru	T L Innerarity		NA
Reitman JS, Mahley RW, Fry DL	Yucatan miniature swine as a model for diet-induced atherosclerosis.	Atherosclerosis	43:1:119-32	1982	7092978		J S Reitman, R W Mahley, D L Fry	J S Reitman	D L Fry		NA
Rall SC, Weisgraber KH, Mahley RW	Human apolipoprotein E. The complete amino acid sequence.	J. Biol. Chem.	257:8:4171-8	1982	7068630		S C Rall, K H Weisgraber, R W Mahley	S C Rall	R W Mahley		NA
Weisgraber KH, Innerarity TL, Mahley RW	Abnormal lipoprotein receptor-binding activity of the human E apoprotein due to cysteine-arginine interchange at a single site.	J. Biol. Chem.	257:5:2518-21	1982	6277903		K H Weisgraber, T L Innerarity, R W Mahley	K H Weisgraber	R W Mahley		NA
Mahley RW	Atherogenic hyperlipoproteinemia. The cellular and molecular biology of plasma lipoproteins altered by dietary fat and cholesterol.	Med. Clin. North Am.	66:2:375-402	1982	7040843		R W Mahley	R W Mahley	R W Mahley		NA
Innerarity TL, Pitas RE, Mahley RW	Modulating effects of canine high density lipoproteins on cholesteryl ester synthesis induced by beta-very low density lipoproteins in macrophages. Possible in vitro correlates with atherosclerosis.	Arteriosclerosis	2:2:114-24		7065981		T L Innerarity, R E Pitas, R W Mahley	T L Innerarity	R W Mahley		NA
Mahley RW, Hui DY, Innerarity TL, Weisgraber KH	Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.	J. Clin. Invest.	68:5:1197-206	1981	6271808		R W Mahley, D Y Hui, T L Innerarity, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Schneider WJ, Kovanen PT, Brown MS, Goldstein JL, Utermann G, Weber W, Havel RJ, Kotite L, Kane JP, Innerarity TL, Mahley RW	Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows.	J. Clin. Invest.	68:4:1075-85	1981	6270194		W J Schneider, P T Kovanen, M S Brown, J L Goldstein, G Utermann, W Weber, R J Havel, L Kotite, J P Kane, T L Innerarity, R W Mahley	W J Schneider	R W Mahley		NA
Weisgraber KH, Rall SC, Mahley RW	Human E apoprotein heterogeneity. Cysteine-arginine interchanges in the amino acid sequence of the apo-E isoforms.	J. Biol. Chem.	256:17:9077-83	1981	7263700		K H Weisgraber, S C Rall, R W Mahley	K H Weisgraber	R W Mahley		NA
Innerarity TL, Kempner ES, Hui DY, Mahley RW	Functional unit of the low density lipoprotein receptor of fibroblasts: a 100,000-dalton structure with multiple binding sites.	Proc. Natl. Acad. Sci. U.S.A.	78:7:4378-82	1981	6270675		T L Innerarity, E S Kempner, D Y Hui, R W Mahley	T L Innerarity	R W Mahley		NA
Hui DY, Innerarity TL, Mahley RW	Lipoprotein binding to canine hepatic membranes. Metabolically distinct apo-E and apo-B,E receptors.	J. Biol. Chem.	256:11:5646-55	1981	6263887		D Y Hui, T L Innerarity, R W Mahley	D Y Hui	R W Mahley		NA
Pitas RE, Innerarity TL, Weinstein JN, Mahley RW	Acetoacetylated lipoproteins used to distinguish fibroblasts from macrophages in vitro by fluorescence microscopy.	Arteriosclerosis	1:3:177-85		6895305		R E Pitas, T L Innerarity, J N Weinstein, R W Mahley	R E Pitas	R W Mahley		NA
Melchior GW, Mahley RW, Buckhold DK	Chylomicron metabolism during dietary-induced hypercholesterolemia in dogs.	J. Lipid Res.	22:4:598-609	1981	7276736		G W Melchior, R W Mahley, D K Buckhold	G W Melchior	D K Buckhold		NA
Fry DL, Mahley RW, Oh SY	Effect of arterial stretch on transmural albumin and Evan's blue dye transport.	Am. J. Physiol.	240:4:H645-9	1981	7223913		D L Fry, R W Mahley, S Y Oh	D L Fry	S Y Oh		NA
Fry DL, Mahley RW, Oh SY, Swyt CR	Aortic transmural serum protein transport: effect of concentration, time, and location.	Am. J. Physiol.	240:1:H54-61	1981	7457622		D L Fry, R W Mahley, S Y Oh, C R Swyt	D L Fry	C R Swyt		NA
Mahley RW	Cellular and molecular biology of lipoprotein metabolism in atherosclerosis.	Diabetes	30:Suppl 2:60-5	1981	7297774		R W Mahley	R W Mahley	R W Mahley		NA
Mahley RW	The role of dietary fat and cholesterol in atherosclerosis and lipoprotein metabolism.	West. J. Med.	134:1:34-42	1981	7210661		R W Mahley	R W Mahley	R W Mahley		NA
Hui DY, Harmony JA, Innerarity TL, Mahley RW	Immunoregulatory plasma lipoproteins. Role of apoprotein E and apoprotein B.	J. Biol. Chem.	255:24:11775-81	1980	7440569		D Y Hui, J A Harmony, T L Innerarity, R W Mahley	D Y Hui	R W Mahley		NHLBI NIH HHS; HL 20882
Innerarity TL, Pitas RE, Mahley RW	Disparities in the interaction of rat and human lipoproteins with cultured rat fibroblasts and smooth muscle cells. Requirements for homology for receptor binding activity.	J. Biol. Chem.	255:23:11163-72	1980	6254962		T L Innerarity, R E Pitas, R W Mahley	T L Innerarity	R W Mahley		NA
Franceschini G, Sirtori CR, Capurso A, Weisgraber KH, Mahley RW	A-IMilano apoprotein. Decreased high density lipoprotein cholesterol levels with significant lipoprotein modifications and without clinical atherosclerosis in an Italian family.	J. Clin. Invest.	66:5:892-900	1980	7430351		G Franceschini, C R Sirtori, A Capurso, K H Weisgraber, R W Mahley	G Franceschini	R W Mahley		NA
Mahley RW, Innerarity TL, Brown MS, Ho YK, Goldstein JL	Cholesteryl ester synthesis in macrophages: stimulation by beta-very low density lipoproteins from cholesterol-fed animals of several species.	J. Lipid Res.	21:8:970-80	1980	7462813		R W Mahley, T L Innerarity, M S Brown, Y K Ho, J L Goldstein	R W Mahley	J L Goldstein		NHLBI NIH HHS; HL 20948
Pitas RE, Nelson GJ, Mahley RW	Effect of cholesterol supplementation of diets of thyroidectomized dogs on the fatty acid composition of erythrocyte phospholipids and plasma phosphatidylcholine.	Biochim. Biophys. Acta	619:3:699-704	1980	7459375		R E Pitas, G J Nelson, R W Mahley	R E Pitas	R W Mahley		NA
Innerarity TL, Pitas RE, Mahley RW	Receptor binding of cholesterol-induced high-density lipoproteins containing predominantly apoprotein E to cultured fibroblasts with mutations at the low-density lipoprotein receptor locus.	Biochemistry	19:18:4359-65	1980	7417411		T L Innerarity, R E Pitas, R W Mahley	T L Innerarity	R W Mahley		NA
Fry DL, Mahley RW, Oh SY, Lewis SJ, Plowman F, Swyt CR	Quantitative microautoradiography of arteries: comparison of radioactivity to silver.	Am. J. Physiol.	239:2:H289-95	1980	6250414		D L Fry, R W Mahley, S Y Oh, S J Lewis, F Plowman, C R Swyt	D L Fry	C R Swyt		NA
Weisgraber KH, Troxler RF, Rall SC, Mahley RW	Comparison of the human, canine and swine E apoproteins.	Biochem. Biophys. Res. Commun.	95:1:374-80	1980	7417263		K H Weisgraber, R F Troxler, S C Rall, R W Mahley	K H Weisgraber	R W Mahley		NIGMS NIH HHS; GM 22822
Pitas RE, Innerarity TL, Mahley RW	Cell surface receptor binding of phospholipid . protein complexes containing different ratios of receptor-active and -inactive E apoprotein.	J. Biol. Chem.	255:11:5454-60	1980	7372644		R E Pitas, T L Innerarity, R W Mahley	R E Pitas	R W Mahley		NA
Goldstein JL, Ho YK, Brown MS, Innerarity TL, Mahley RW	Cholesteryl ester accumulation in macrophages resulting from receptor-mediated uptake and degradation of hypercholesterolemic canine beta-very low density lipoproteins.	J. Biol. Chem.	255:5:1839-48	1980	7354064		J L Goldstein, Y K Ho, M S Brown, T L Innerarity, R W Mahley	J L Goldstein	R W Mahley		NA
Sherrill BC, Innerarity TL, Mahley RW	Rapid hepatic clearance of the canine lipoproteins containing only the E apoprotein by a high affinity receptor. Identity with the chylomicron remnant transport process.	J. Biol. Chem.	255:5:1804-7	1980	7354059		B C Sherrill, T L Innerarity, R W Mahley	B C Sherrill	R W Mahley		NA
Weisgraber KH, Mahley RW	Subfractionation of human high density lipoproteins by heparin-Sepharose affinity chromatography.	J. Lipid Res.	21:3:316-25	1980	7381326		K H Weisgraber, R W Mahley	K H Weisgraber	R W Mahley		NA
Mahley RW, Johnson DK, Pucak GJ, Fry DL	Atherosclerosis in the Erythrocebus patas, an old world monkey.	Am. J. Pathol.	98:2:401-24	1980	6766672		R W Mahley, D K Johnson, G J Pucak, D L Fry	R W Mahley	D L Fry		NA
Mahley RW, Innerarity TL, Weisgraber KH	Alterations in metabolic activity of plasma lipoproteins following selective chemical modification of the apoproteins.	Ann. N. Y. Acad. Sci.	348:265-80	1980	6994562		R W Mahley, T L Innerarity, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Mahley RW, Weisgraber KH, Melchior GW, Innerarity TL, Holcombe KS	Inhibition of receptor-mediated clearance of lysine and arginine-modified lipoproteins from the plasma of rats and monkeys.	Proc. Natl. Acad. Sci. U.S.A.	77:1:225-9	1980	6767236		R W Mahley, K H Weisgraber, G W Melchior, T L Innerarity, K S Holcombe	R W Mahley	K S Holcombe		NA
Reitman JS, Mahley RW	Changes induced in the lipoproteins of Yucatan miniature swine by cholesterol feeding.	Biochim. Biophys. Acta	575:3:446-57	1979	518896		J S Reitman, R W Mahley	J S Reitman	R W Mahley		NA
Mahley RW, Weisgraber KH, Innerarity TL	Interaction of plasma lipoproteins containing apolipoproteins B and E with heparin and cell surface receptors.	Biochim. Biophys. Acta	575:1:81-91	1979	228738		R W Mahley, K H Weisgraber, T L Innerarity	R W Mahley	T L Innerarity		NA
Mahley RW, Innerarity TL, Weisgraber KB, Oh SY	Altered metabolism (in vivo and in vitro) of plasma lipoproteins after selective chemical modification of lysine residues of the apoproteins.	J. Clin. Invest.	64:3:743-50	1979	224077		R W Mahley, T L Innerarity, K B Weisgraber, S Y Oh	R W Mahley	S Y Oh		NA
Innerarity TL, Pitas RE, Mahley RW	Binding of arginine-rich (E) apoprotein after recombination with phospholipid vesicles to the low density lipoprotein receptors of fibroblasts.	J. Biol. Chem.	254:10:4186-90	1979	220235		T L Innerarity, R E Pitas, R W Mahley	T L Innerarity	R W Mahley		NA
Pitas RE, Innerarity TL, Arnold KS, Mahley RW	Rate and equilibrium constants for binding of apo-E HDLc (a cholesterol-induced lipoprotein) and low density lipoproteins to human fibroblasts: evidence for multiple receptor binding of apo-E HDLc.	Proc. Natl. Acad. Sci. U.S.A.	76:5:2311-5	1979	221921		R E Pitas, T L Innerarity, K S Arnold, R W Mahley	R E Pitas	R W Mahley		NA
Pitas RE, Nelson GJ, Jaffe RM, Mahley RW	Effects of diets high in saturated fat and cholesterol on the lipid composition of canine platelets.	Lipids	14:5:469-77	1979	459712		R E Pitas, G J Nelson, R M Jaffe, R W Mahley	R E Pitas	R W Mahley		NA
Mahley RW, Weisgraber KH, Innerarity TL, Windmueller HG	Accelerated clearance of low-density and high-density lipoproteins and retarded clearance of E apoprotein-containing lipoproteins from the plasma of rats after modification of lysine residues.	Proc. Natl. Acad. Sci. U.S.A.	76:4:1746-50	1979	221905		R W Mahley, K H Weisgraber, T L Innerarity, H G Windmueller	R W Mahley	H G Windmueller		NA
Weisgraber KH, Innerarity TL, Mahley RW	Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.	J. Biol. Chem.	253:24:9053-62	1978	214439		K H Weisgraber, T L Innerarity, R W Mahley	K H Weisgraber	R W Mahley		NA
Atkinson D, Tall AR, Small DM, Mahley RW	Structural organization of the lipoprotein HDLc from atherosclerotic swine. Structural features relating the particle surface and core.	Biochemistry	17:19:3930-3	1978	213098		D Atkinson, A R Tall, D M Small, R W Mahley	D Atkinson	R W Mahley		NA
Weisgraber KH, Mahley RW	Apoprotein (E--A-II) complex of human plasma lipoproteins. I. Characterization of this mixed disulfide and its identification in a high density lipoprotein subfraction.	J. Biol. Chem.	253:17:6281-8	1978	210174		K H Weisgraber, R W Mahley	K H Weisgraber	R W Mahley		NA
Pitas RE, Nelson GJ, Jaffe RM, Mahley RW	delta 15,18-tetracosadienoic acid content of sphingolipids from platelets and erythrocytes of animals fed diets high in saturated or polyunsaturated fats.	Lipids	13:8:551-6	1978	703532		R E Pitas, G J Nelson, R M Jaffe, R W Mahley	R E Pitas	R W Mahley		NA
Innerarity TL, Mahley RW	Enhanced binding by cultured human fibroblasts of apo-E-containing lipoproteins as compared with low density lipoproteins.	Biochemistry	17:8:1440-7	1978	206278		T L Innerarity, R W Mahley	T L Innerarity	R W Mahley		NA
Mahley RW, Innerarity TL	Properties of lipoproteins responsible for high affinity binding to cell surface receptors of fibroblasts and smooth muscle cells.	Adv. Exp. Med. Biol.	109:99-127	1978	364953		R W Mahley, T L Innerarity	R W Mahley	T L Innerarity		NA
Mahley RW, Innerarity TL, Pitas RE, Weisgraber KH, Brown JH, Gross E	Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins.	J. Biol. Chem.	252:20:7279-87	1977	198407		R W Mahley, T L Innerarity, R E Pitas, K H Weisgraber, J H Brown, E Gross	R W Mahley	E Gross		NA
Tall AR, Atkinson D, Small DM, Mahley RW	Characterization of the lipoproteins of atherosclerotic swine.	J. Biol. Chem.	252:20:7288-93	1977	198408		A R Tall, D Atkinson, D M Small, R W Mahley	A R Tall	R W Mahley		NA
Weisgraber KH, Mahley RW, Assmann G	The rat arginine-rich apoprotein and its redistribution following injection of iodinated lipoproteins into normal and hypercholesterolemic rats.	Atherosclerosis	28:2:121-40	1977	199205		K H Weisgraber, R W Mahley, G Assmann	K H Weisgraber	G Assmann		NA
Fry DL, Mahley RW, Weisgraber KH, Oh SY	Simultaneous accumulation of Evans blue dye and albumin in the canine aortic wall.	Am. J. Physiol.	233:1:H66-79	1977	879338		D L Fry, R W Mahley, K H Weisgraber, S Y Oh	D L Fry	S Y Oh		NA
Mahley RW, Innerarity TL	Interaction of canine and swine lipoproteins with the low density lipoprotein receptor of fibroblasts as correlated with heparin/manganese precipitability.	J. Biol. Chem.	252:11:3980-6	1977	193851		R W Mahley, T L Innerarity	R W Mahley	T L Innerarity		NA
Mahley RW, Holcombe KS	Alterations of the plasma lipoproteins and apoproteins following cholesterol feeding in the rat.	J. Lipid Res.	18:3:314-24	1977	194008		R W Mahley, K S Holcombe	R W Mahley	K S Holcombe		NA
Mahley RW, Innerarity TL, Weisgraber KH, Fry DL	Canine hyperlipoproteinemia and atherosclerosis. Accumulation of lipid by aortic medial cells in vivo and in vitro.	Am. J. Pathol.	87:1:205-26	1977	192082		R W Mahley, T L Innerarity, K H Weisgraber, D L Fry	R W Mahley	D L Fry		NA
Mahley RW	Lipoproteins and arterial smooth muscle cells: regulation of cellular metabolism by swine lipoproteins.	Adv. Exp. Med. Biol.	82:909-14	1977	920447		R W Mahley	R W Mahley	R W Mahley		NA
Brown BG, Mahley R, Assmann G	Swine aortic smooth muscle in tissue culture. Some effects of purified swine lipoproteins on cell growth and morphology.	Circ. Res.	39:3:415-24	1976	182413		B G Brown, R Mahley, G Assmann	B G Brown	G Assmann		NA
Mahley RW, Weisgraber KH, Innerarity T	Atherogenic hyperlipoproteinemia induced by cholesterol feeding the Patas monkey.	Biochemistry	15:14:2979-85	1976	182200		R W Mahley, K H Weisgraber, T Innerarity	R W Mahley	T Innerarity		NA
Mahley R, Nelson AW, Ferrans VJ, Fry DL	Thrombosis in association with atherosclerosis induced by dietary perturbations in dogs.	Science	192:4244:1139-41	1976	1273587		R Mahley, A W Nelson, V J Ferrans, D L Fry	R Mahley	D L Fry		NA
Mahley RW, Weisgraber KH, Innerarity T, Brewer HB	Characterization of the plasma lipoproteins and apoproteins of the Erythrocebus patas monkey.	Biochemistry	15:9:1928-33	1976	178359		R W Mahley, K H Weisgraber, T Innerarity, H B Brewer	R W Mahley	H B Brewer		NA
Mahley RW, Weisgraber KH, Innerarity T, Brewer HB, Assmann G	Swine lipoproteins and atherosclerosis. Changes in the plasma lipoproteins and apoproteins induced by cholesterol feeding.	Biochemistry	14:13:2817-23	1975	167808		R W Mahley, K H Weisgraber, T Innerarity, H B Brewer, G Assmann	R W Mahley	G Assmann		NA
Mahley RW, Weisgraber KH, Innerarity T	Canine lipoproteins and atherosclerosis. II. Characterization of the plasma lipoproteins associated with atherogenic and nonatherogenic hyperlipidemia.	Circ. Res.	35:5:722-33	1974	4138629		R W Mahley, K H Weisgraber, T Innerarity	R W Mahley	T Innerarity		NA
Mahley RW, Weisgraber KH	Canine lipoproteins and atherosclerosis. I. Isolation and characterization of plasma lipoproteins from control dogs.	Circ. Res.	35:5:713-21	1974	4138628		R W Mahley, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Wetmore S, Mahley RW, Brown WV, Schachter H	Incorporation of sialic acid into sialidase-treated apolipoprotein of human, very low density lipoprotein by a pork liver sialytransferase.	Can. J. Biochem.	52:8:654-64	1974	4373146		S Wetmore, R W Mahley, W V Brown, H Schachter	S Wetmore	H Schachter		NA
Mahley RW, Weisgraber KH	An electrophoretic method for the quantitative isolation of human and swine plasma lipoproteins.	Biochemistry	13:9:1964-9	1974	4366269		R W Mahley, K H Weisgraber	R W Mahley	K H Weisgraber		NA
Assmann G, Mahley RW, Davis B, Holcombe KS	Cholesterol esterification by the rat liver Golgi apparatus.	Scand. J. Clin. Lab. Invest. Suppl.	137:23-8	1974	4367598		G Assmann, R W Mahley, B Davis, K S Holcombe	G Assmann	K S Holcombe		NA
Mahley RW, Gray ME, LeQuire VS	Role of plasma lipoproteins in cortisone-induced fat embolism.	Am. J. Pathol.	66:1:43-64	1972	5009252		R W Mahley, M E Gray, V S LeQuire	R W Mahley	V S LeQuire		NA
Mahley RW, Bennett BD, Morré DJ, Gray ME, Thistlethwaite W, LeQuire VS	Lipoproteins associated with the Golgi apparatus isolated from epithelial cells of rat small intestine.	Lab. Invest.	25:5:435-44	1971	4109439		R W Mahley, B D Bennett, D J Morré, M E Gray, W Thistlethwaite, V S LeQuire	R W Mahley	V S LeQuire		NA
Engel E, Culbertson JC, Mahley RW, Fenichel GM	Barr body studies from the hair.	Lancet	1:7650:789	1970	4191300		E Engel, J C Culbertson, R W Mahley, G M Fenichel	E Engel	G M Fenichel		NA
Morré DJ, Hamilton RL, Mollenhauer HH, Mahley RW, Cunningham WP, Cheetham RD, Lequire VS	Isolation of a Golgi apparatus-rich fraction from rat liver. I. Method and morphology.	J. Cell Biol.	44:3:484-91	1970	4905956		D J Morré, R L Hamilton, H H Mollenhauer, R W Mahley, W P Cunningham, R D Cheetham, V S Lequire	D J Morré	V S Lequire		NA
Mahley RW, Hamilton RL, Lequire VS	Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver.	J. Lipid Res.	10:4:433-9	1969	4978881		R W Mahley, R L Hamilton, V S Lequire	R W Mahley	V S Lequire		NA
Mahley RW, Gray ME, Hamilton RL, LeQuire VS	Lipid transport in liver. II. Electron microscopic and biochemical studies of alterations in lipoprotein transport induced by cortisone in the rabbit.	Lab. Invest.	19:4:358-69	1968	5699116		R W Mahley, M E Gray, R L Hamilton, V S LeQuire	R W Mahley	V S LeQuire		NA
Sharpton TJ, Jospin G, Wu D, Langille MG, Pollard KS, Eisen JA	Sifting through genomes with iterative-sequence clustering produces a large, phylogenetically diverse protein-family resource.	BMC Bioinformatics	13:264	2012	23061897		Thomas J Sharpton, Guillaume Jospin, Dongying Wu, Morgan G I Langille, Katherine S Pollard, Jonathan A Eisen	Thomas J Sharpton	Jonathan A Eisen	The J. David Gladstone Institutes, University of California San Francisco, San Francisco, CA 94158, USA. thomas.sharpton@gladstone.ucsf.edu	NA
Lemay DG, Martin WF, Hinrichs AS, Rijnkels M, German JB, Korf I, Pollard KS	G-NEST: a gene neighborhood scoring tool to identify co-conserved, co-expressed genes.	BMC Bioinformatics	13:253	2012	23020263		Danielle G Lemay, William F Martin, Angie S Hinrichs, Monique Rijnkels, J Bruce German, Ian Korf, Katherine S Pollard	Danielle G Lemay	Katherine S Pollard	Genome Center, University of California Davis, 451 Health Science Dr, Davis, CA, 95616, United States of America. dglemay@ucdavis.edu	NIGMS NIH HHS; GM082901
Capra JA, Williams AG, Pollard KS	ProteinHistorian: tools for the comparative analysis of eukaryote protein origin.	PLoS Comput. Biol.	8:6:e1002567	2012	22761559		John A Capra, Alexander G Williams, Katherine S Pollard	John A Capra	Katherine S Pollard	J. David Gladstone Institutes, University of California, San Francisco, California, United States of America. tony.capra@gladstone.ucsf.edu	NIGMS NIH HHS; GM82901
Wylie KM, Truty RM, Sharpton TJ, Mihindukulasuriya KA, Zhou Y, Gao H, Sodergren E, Weinstock GM, Pollard KS	Novel bacterial taxa in the human microbiome.	PLoS ONE	7:6:e35294	2012	22719826		Kristine M Wylie, Rebecca M Truty, Thomas J Sharpton, Kathie A Mihindukulasuriya, Yanjiao Zhou, Hongyu Gao, Erica Sodergren, George M Weinstock, Katherine S Pollard	Kristine M Wylie	Katherine S Pollard	The Genome Institute, Washington University School of Medicine, St Louis, Missouri, United States of America. kwylie@genome.wustl.edu	NHGRI NIH HHS; U54HG004968
Burbano HA, Green RE, Maricic T, Lalueza-Fox C, de la Rasilla M, Rosas A, Kelso J, Pollard KS, Lachmann M, Pääbo S	Analysis of human accelerated DNA regions using archaic hominin genomes.	PLoS ONE	7:3:e32877	2012	22412940		Hernán A Burbano, Richard E Green, Tomislav Maricic, Carles Lalueza-Fox, Marco de la Rasilla, Antonio Rosas, Janet Kelso, Katherine S Pollard, Michael Lachmann, Svante Pääbo	Hernán A Burbano	Svante Pääbo	Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. hernan.a.burbano@googlemail.com	NIGMS NIH HHS; GM082901
Kostka D, Hubisz MJ, Siepel A, Pollard KS	The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome.	Mol. Biol. Evol.	29:3:1047-57	2012	22075116		Dennis Kostka, Melissa J Hubisz, Adam Siepel, Katherine S Pollard	Dennis Kostka	Katherine S Pollard	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, USA. dennis.kostka@gladstone.ucsf.edu	NIGMS NIH HHS; GM82901
Lindblad-Toh K, Garber M, Zuk O, Lin MF, Parker BJ, Washietl S, Kheradpour P, Ernst J, Jordan G, Mauceli E, Ward LD, Lowe CB, Holloway AK, Clamp M, Gnerre S, Alföldi J, Beal K, Chang J, Clawson H, Cuff J, Di Palma F, Fitzgerald S, Flicek P, Guttman M, Hubisz MJ, Jaffe DB, Jungreis I, Kent WJ, Kostka D, Lara M, Martins AL, Massingham T, Moltke I, Raney BJ, Rasmussen MD, Robinson J, Stark A, Vilella AJ, Wen J, Xie X, Zody MC, Baldwin J, Bloom T, Chin CW, Heiman D, Nicol R, Nusbaum C, Young S, Wilkinson J, Worley KC, Kovar CL, Muzny DM, Gibbs RA, Cree A, Dihn HH, Fowler G, Jhangiani S, Joshi V, Lee S, Lewis LR, Nazareth LV, Okwuonu G, Santibanez J, Warren WC, Mardis ER, Weinstock GM, Wilson RK, Delehaunty K, Dooling D, Fronik C, Fulton L, Fulton B, Graves T, Minx P, Sodergren E, Birney E, Margulies EH, Herrero J, Green ED, Haussler D, Siepel A, Goldman N, Pollard KS, Pedersen JS, Lander ES, Kellis M	A high-resolution map of human evolutionary constraint using 29 mammals.	Nature	478:7370:476-82	2011	21993624		Kerstin Lindblad-Toh, Manuel Garber, Or Zuk, Michael F Lin, Brian J Parker, Stefan Washietl, Pouya Kheradpour, Jason Ernst, Gregory Jordan, Evan Mauceli, Lucas D Ward, Craig B Lowe, Alisha K Holloway, Michele Clamp, Sante Gnerre, Jessica Alföldi, Kathryn Beal, Jean Chang, Hiram Clawson, James Cuff, Federica Di Palma, Stephen Fitzgerald, Paul Flicek, Mitchell Guttman, Melissa J Hubisz, David B Jaffe, Irwin Jungreis, W James Kent, Dennis Kostka, Marcia Lara, Andre L Martins, Tim Massingham, Ida Moltke, Brian J Raney, Matthew D Rasmussen, Jim Robinson, Alexander Stark, Albert J Vilella, Jiayu Wen, Xiaohui Xie, Michael C Zody, Jen Baldwin, Toby Bloom, Chee Whye Chin, Dave Heiman, Robert Nicol, Chad Nusbaum, Sarah Young, Jane Wilkinson, Kim C Worley, Christie L Kovar, Donna M Muzny, Richard A Gibbs, Andrew Cree, Huyen H Dihn, Gerald Fowler, Shalili Jhangiani, Vandita Joshi, Sandra Lee, Lora R Lewis, Lynne V Nazareth, Geoffrey Okwuonu, Jireh Santibanez, Wesley C Warren, Elaine R Mardis, George M Weinstock, Richard K Wilson, Kim Delehaunty, David Dooling, Catrina Fronik, Lucinda Fulton, Bob Fulton, Tina Graves, Patrick Minx, Erica Sodergren, Ewan Birney, Elliott H Margulies, Javier Herrero, Eric D Green, David Haussler, Adam Siepel, Nick Goldman, Katherine S Pollard, Jakob S Pedersen, Eric S Lander, Manolis Kellis	Kerstin Lindblad-Toh	Manolis Kellis	Broad Institute of Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA. kersli@broadinstitute.org	Howard Hughes Medical Institute; 
Kembel SW, Eisen JA, Pollard KS, Green JL	The phylogenetic diversity of metagenomes.	PLoS ONE	6:8:e23214	2011	21912589		Steven W Kembel, Jonathan A Eisen, Katherine S Pollard, Jessica L Green	Steven W Kembel	Jessica L Green	Institute of Ecology and Evolution, University of Oregon, Eugene, Oregon, United States of America. skembel@uoregon.edu	NA
Katzman S, Capra JA, Haussler D, Pollard KS	Ongoing GC-biased evolution is widespread in the human genome and enriched near recombination hot spots.	Genome Biol Evol	3:614-26	2011	21697099		Sol Katzman, John A Capra, David Haussler, Katherine S Pollard	Sol Katzman	Katherine S Pollard	Center for Biomolecular Science and Engineering, University of California, Santa Cruz, USA.	Howard Hughes Medical Institute; 
Capra JA, Pollard KS	Substitution patterns are GC-biased in divergent sequences across the metazoans.	Genome Biol Evol	3:516-27	2011	21670083		John A Capra, Katherine S Pollard	John A Capra	Katherine S Pollard	Gladstone Institutes, University of California, San Francisco, USA.	NIGMS NIH HHS; GM82901
Hirschey MD, Shimazu T, Capra JA, Pollard KS, Verdin E	SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2.	Aging (Albany NY)	3:6:635-42	2011	21701047		Matthew D Hirschey, Tadahiro Shimazu, John A Capra, Katherine S Pollard, Eric Verdin	Matthew D Hirschey	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NCRR NIH HHS; RR18928-01
Lambert N, Lambot MA, Bilheu A, Albert V, Englert Y, Libert F, Noel JC, Sotiriou C, Holloway AK, Pollard KS, Detours V, Vanderhaeghen P	Genes expressed in specific areas of the human fetal cerebral cortex display distinct patterns of evolution.	PLoS ONE	6:3:e17753	2011	21445258		Nelle Lambert, Marie-Alexandra Lambot, Angéline Bilheu, Valérie Albert, Yvon Englert, Frédérick Libert, Jean-Christophe Noel, Christos Sotiriou, Alisha K Holloway, Katherine S Pollard, Vincent Detours, Pierre Vanderhaeghen	Nelle Lambert	Pierre Vanderhaeghen	Institut de Recherches en Biologie Humaine et Moléculaire (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium.	NA
Sharpton TJ, Riesenfeld SJ, Kembel SW, Ladau J, O'Dwyer JP, Green JL, Eisen JA, Pollard KS	PhylOTU: a high-throughput procedure quantifies microbial community diversity and resolves novel taxa from metagenomic data.	PLoS Comput. Biol.	7:1:e1001061	2011	21283775		Thomas J Sharpton, Samantha J Riesenfeld, Steven W Kembel, Joshua Ladau, James P O'Dwyer, Jessica L Green, Jonathan A Eisen, Katherine S Pollard	Thomas J Sharpton	Katherine S Pollard	The J. David Gladstone Institutes, University of California San Francisco, San Francisco, California, United States of America. thomas.sharpton@gladstone.ucsf.edu	NA
Capra JA, Pollard KS, Singh M	Novel genes exhibit distinct patterns of function acquisition and network integration.	Genome Biol.	11:12:R127	2010	21187012		John A Capra, Katherine S Pollard, Mona Singh	John A Capra	Mona Singh	Gladstone Institutes, University of California, San Francisco, 1650 Owens St, San Francisco, CA 94158, USA. tony.capra@gladstone.ucsf.edu	NHGRI NIH HHS; T32 HG003284
Hubisz MJ, Pollard KS, Siepel A	PHAST and RPHAST: phylogenetic analysis with space/time models.	Brief. Bioinformatics	12:1:41-51	2011	21278375		Melissa J Hubisz, Katherine S Pollard, Adam Siepel	Melissa J Hubisz	Adam Siepel	Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA. acs4@cornell.edu	NIGMS NIH HHS; R01-GM082901
Kostka D, Hahn MW, Pollard KS	Noncoding sequences near duplicated genes evolve rapidly.	Genome Biol Evol	2:518-33	2010	20660939		Dennis Kostka, Matthew W Hahn, Katherine S Pollard	Dennis Kostka	Katherine S Pollard	Gladstone Institute for Cardiovascular Disease, Gladstone Institutes, University of California-San Francisco, San Francisco, CA, USA. dennis.kostka@gladstone.ucsf.edu	NIGMS NIH HHS; GM82901
Ritter DI, Li Q, Kostka D, Pollard KS, Guo S, Chuang JH	The importance of being cis: evolution of orthologous fish and mammalian enhancer activity.	Mol. Biol. Evol.	27:10:2322-32	2010	20494938		Deborah I Ritter, Qiang Li, Dennis Kostka, Katherine S Pollard, Su Guo, Jeffrey H Chuang	Deborah I Ritter	Jeffrey H Chuang	Department of Biology, Boston College, Chestnut Hill, Massachusetts, USA.	NINDS NIH HHS; NS042626
Katzman S, Kern AD, Pollard KS, Salama SR, Haussler D	GC-biased evolution near human accelerated regions.	PLoS Genet.	6:5:e1000960	2010	20502635		Sol Katzman, Andrew D Kern, Katherine S Pollard, Sofie R Salama, David Haussler	Sol Katzman	David Haussler	Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America.	Howard Hughes Medical Institute; 
Taylor SL, Pollard KS	Composite interval mapping to identify quantitative trait loci for point-mass mixture phenotypes.	Genet Res (Camb)	92:1:39-53	2010	20196895		Sandra L Taylor, Katherine S Pollard	Sandra L Taylor	Katherine S Pollard	Biostatistics Graduate Group, University of California-Davis, One Shields Avenue, Davis, CA 95616, USA. sltaylor@ucdavis.edu	NA
Pollard KS, Hubisz MJ, Rosenbloom KR, Siepel A	Detection of nonneutral substitution rates on mammalian phylogenies.	Genome Res.	20:1:110-21	2010	19858363		Katherine S Pollard, Melissa J Hubisz, Kate R Rosenbloom, Adam Siepel	Katherine S Pollard	Adam Siepel	Gladstone Institutes, University of California, San Francisco, San Francisco, California 94158, USA. kpollard@gladstone.ucsf.edu	NIGMS NIH HHS; GM82901
Hsieh F, Chen SC, Pollard K	A nearly exhaustive search for CpG islands on whole chromosomes.	Int J Biostat	5:1:	2009	20148132		Fushing Hsieh, Shu-Chun Chen, Katherine Pollard	Fushing Hsieh	Katherine Pollard	Department of Statistics, Mathematical Sciences Building, University of California, Davis, CA 95616, USA. fushing@wald.ucdavis.edu	NIA NIH HHS; R01 AG025218-02
Pollard KS	What makes us human?	Sci. Am.	300:5:44-9	2009	19438048		Katherine S Pollard	Katherine S Pollard	Katherine S Pollard	University of California, San Francisco, USA.	NA
Lemay DG, Lynn DJ, Martin WF, Neville MC, Casey TM, Rincon G, Kriventseva EV, Barris WC, Hinrichs AS, Molenaar AJ, Pollard KS, Maqbool NJ, Singh K, Murney R, Zdobnov EM, Tellam RL, Medrano JF, German JB, Rijnkels M	The bovine lactation genome: insights into the evolution of mammalian milk.	Genome Biol.	10:4:R43	2009	19393040		Danielle G Lemay, David J Lynn, William F Martin, Margaret C Neville, Theresa M Casey, Gonzalo Rincon, Evgenia V Kriventseva, Wesley C Barris, Angie S Hinrichs, Adrian J Molenaar, Katherine S Pollard, Nauman J Maqbool, Kuljeet Singh, Regan Murney, Evgeny M Zdobnov, Ross L Tellam, Juan F Medrano, J Bruce German, Monique Rijnkels	Danielle G Lemay	Monique Rijnkels	Department of Food Science and Technology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA. dglemay@ucdavis.edu	NIEHS NIH HHS; P42 ES04699
Taylor S, Pollard K	Hypothesis tests for point-mass mixture data with application to 'omics data with many zero values.	Stat Appl Genet Mol Biol	8:Article 8	2009	19222391		Sandra Taylor, Katherine Pollard	Sandra Taylor	Katherine Pollard	University of California, Davis, USA. staylor@wald.ucdavis.edu	NA
Berglund J, Pollard KS, Webster MT	Hotspots of biased nucleotide substitutions in human genes.	PLoS Biol.	7:1:e26	2009	19175294		Jonas Berglund, Katherine S Pollard, Matthew T Webster	Jonas Berglund	Matthew T Webster	Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.	NIGMS NIH HHS; GM82901-01A1
Cozen AE, Weirauch MT, Pollard KS, Bernick DL, Stuart JM, Lowe TM	Transcriptional map of respiratory versatility in the hyperthermophilic crenarchaeon Pyrobaculum aerophilum.	J. Bacteriol.	191:3:782-94	2009	19047344		Aaron E Cozen, Matthew T Weirauch, Katherine S Pollard, David L Bernick, Joshua M Stuart, Todd M Lowe	Aaron E Cozen	Todd M Lowe	Department of Ocean Sciences, University of California Santa Cruz, 1156 High Street, Santa Cruz, California 95064, USA.	NA
Pollard KS, van der Laan MJ	Supervised distance matrices.	Stat Appl Genet Mol Biol	7:1:Article 33	2008	19049489		Katherine S Pollard, Mark J van der Laan	Katherine S Pollard	Mark J van der Laan	University of California, San Francisco, USA. kpollard@gladstone.ucsf.edu	NA
Walker WL, Liao IH, Gilbert DL, Wong B, Pollard KS, McCulloch CE, Lit L, Sharp FR	Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients.	BMC Genomics	9:494	2008	18937867		Wynn L Walker, Isaac H Liao, Donald L Gilbert, Brenda Wong, Katherine S Pollard, Charles E McCulloch, Lisa Lit, Frank R Sharp	Wynn L Walker	Frank R Sharp	Department of Neurology and MIND Institute, University of California at Davis, Sacramento, California, USA. wwalker@ucdavis.edu	NA
Taylor SL, Pollard KS	Evaluation of two methods to estimate and monitor bird populations.	PLoS ONE	3:8:e3047	2008	18728775		Sandra L Taylor, Katherine S Pollard	Sandra L Taylor	Katherine S Pollard	Department of Statistics, University of California Davis, Davis, California, USA. sltaylor@ucdavis.edu	NA
Holloway AK, Begun DJ, Siepel A, Pollard KS	Accelerated sequence divergence of conserved genomic elements in Drosophila melanogaster.	Genome Res.	18:10:1592-601	2008	18583644		Alisha K Holloway, David J Begun, Adam Siepel, Katherine S Pollard	Alisha K Holloway	Katherine S Pollard	Department of Evolution and Ecology and Center for Population Biology, University of California, Davis, California 95691, USA. akholloway@ucdavis.edu	NIGMS NIH HHS; R01-GM071926
Lemay DG, Neville MC, Rudolph MC, Pollard KS, German JB	Gene regulatory networks in lactation: identification of global principles using bioinformatics.	BMC Syst Biol	1:56	2007	18039394		Danielle G Lemay, Margaret C Neville, Michael C Rudolph, Katherine S Pollard, J Bruce German	Danielle G Lemay	J Bruce German	Department of Food Science and Technology, University of California, One Shields Ave,, Davis, CA 95616, USA. dglemay@ucdavis.edu	NIEHS NIH HHS; P42 ES04699
Pollard KS, Serre D, Wang X, Tao H, Grundberg E, Hudson TJ, Clark AG, Frazer K	A genome-wide approach to identifying novel-imprinted genes.	Hum. Genet.	122:6:625-34	2008	17955261		Katherine S Pollard, David Serre, Xu Wang, Heng Tao, Elin Grundberg, Thomas J Hudson, Andrew G Clark, Kelly Frazer	Katherine S Pollard	Kelly Frazer	UC Davis Genome Center and Department of Statistics, University of California, Davis, CA, 95616, USA. kspollard@ucdavis.edu	NA
Dreszer TR, Wall GD, Haussler D, Pollard KS	Biased clustered substitutions in the human genome: the footprints of male-driven biased gene conversion.	Genome Res.	17:10:1420-30	2007	17785536		Timothy R Dreszer, Gregory D Wall, David Haussler, Katherine S Pollard	Timothy R Dreszer	Katherine S Pollard	Department of Biomolecular Engineering, University of California, Santa Cruz, California 95064, USA.	NA
Magalhães TR, Palmer J, Tomancak P, Pollard KS	Transcriptional control in embryonic Drosophila midline guidance assessed through a whole genome approach.	BMC Neurosci	8:59	2007	17672901		Tiago R Magalhães, Jessica Palmer, Pavel Tomancak, Katherine S Pollard	Tiago R Magalhães	Katherine S Pollard	Programa Gulbenkian Doutoramento Biologia e Medicina, Centro Neurociências, Universidade de Coimbra, 3000-Coimbra, Portugal. tiago17@socrates.berkeley.edu	NA
Pollard KS, Salama SR, King B, Kern AD, Dreszer T, Katzman S, Siepel A, Pedersen JS, Bejerano G, Baertsch R, Rosenbloom KR, Kent J, Haussler D	Forces shaping the fastest evolving regions in the human genome.	PLoS Genet.	2:10:e168	2006	17040131		Katherine S Pollard, Sofie R Salama, Bryan King, Andrew D Kern, Tim Dreszer, Sol Katzman, Adam Siepel, Jakob S Pedersen, Gill Bejerano, Robert Baertsch, Kate R Rosenbloom, Jim Kent, David Haussler	Katherine S Pollard	David Haussler	Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, California, United States of America. kspollard@ucdavis.edu	NHGRI NIH HHS; P41 HG02371
Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, Pedersen JS, Katzman S, King B, Onodera C, Siepel A, Kern AD, Dehay C, Igel H, Ares M, Vanderhaeghen P, Haussler D	An RNA gene expressed during cortical development evolved rapidly in humans.	Nature	443:7108:167-72	2006	16915236		Katherine S Pollard, Sofie R Salama, Nelle Lambert, Marie-Alexandra Lambot, Sandra Coppens, Jakob S Pedersen, Sol Katzman, Bryan King, Courtney Onodera, Adam Siepel, Andrew D Kern, Colette Dehay, Haller Igel, Manuel Ares, Pierre Vanderhaeghen, David Haussler	Katherine S Pollard	David Haussler	Center for Biomolecular Science & Engineering, Department of Molecular, Cell & Developmental Biology, University of California, Santa Cruz, California 95064, USA.	NA
Beaulieu JP, Bennett DP, Fouqué P, Williams A, Dominik M, Jørgensen UG, Kubas D, Cassan A, Coutures C, Greenhill J, Hill K, Menzies J, Sackett PD, Albrow M, Brillant S, Caldwell JA, Calitz JJ, Cook KH, Corrales E, Desort M, Dieters S, Dominis D, Donatowicz J, Hoffman M, Kane S, Marquette JB, Martin R, Meintjes P, Pollard K, Sahu K, Vinter C, Wambsganss J, Woller K, Horne K, Steele I, Bramich DM, Burgdorf M, Snodgrass C, Bode M, Udalski A, Szymański MK, Kubiak M, Wieckowski T, Pietrzyński G, Soszyński I, Szewczyk O, Wyrzykowski L, Paczyński B, Abe F, Bond IA, Britton TR, Gilmore AC, Hearnshaw JB, Itow Y, Kamiya K, Kilmartin PM, Korpela AV, Masuda K, Matsubara Y, Motomura M, Muraki Y, Nakamura S, Okada C, Ohnishi K, Rattenbury NJ, Sako T, Sato S, Sasaki M, Sekiguchi T, Sullivan DJ, Tristram PJ, Yock PC, Yoshioka T	Discovery of a cool planet of 5.5 Earth masses through gravitational microlensing.	Nature	439:7075:437-40	2006	16437108		J-P Beaulieu, D P Bennett, P Fouqué, A Williams, M Dominik, U G Jørgensen, D Kubas, A Cassan, C Coutures, J Greenhill, K Hill, J Menzies, P D Sackett, M Albrow, S Brillant, J A R Caldwell, J J Calitz, K H Cook, E Corrales, M Desort, S Dieters, D Dominis, J Donatowicz, M Hoffman, S Kane, J-B Marquette, R Martin, P Meintjes, K Pollard, K Sahu, C Vinter, J Wambsganss, K Woller, K Horne, I Steele, D M Bramich, M Burgdorf, C Snodgrass, M Bode, A Udalski, M K Szymański, M Kubiak, T Wieckowski, G Pietrzyński, I Soszyński, O Szewczyk, L Wyrzykowski, B Paczyński, F Abe, I A Bond, T R Britton, A C Gilmore, J B Hearnshaw, Y Itow, K Kamiya, P M Kilmartin, A V Korpela, K Masuda, Y Matsubara, M Motomura, Y Muraki, S Nakamura, C Okada, K Ohnishi, N J Rattenbury, T Sako, S Sato, M Sasaki, T Sekiguchi, D J Sullivan, P J Tristram, P C M Yock, T Yoshioka	J-P Beaulieu	T Yoshioka	PLANET/RoboNet Collaboration, CNRS, Université Pierre et Marie Curie UMR7095, 98bis Boulevard Arago, 75014 Paris, France. beaulieu@iap.fr	NA
Schneider KL, Pollard KS, Baertsch R, Pohl A, Lowe TM	The UCSC Archaeal Genome Browser.	Nucleic Acids Res.	34:Database issue:D407-10	2006	16381898		Kevin L Schneider, Katherine S Pollard, Robert Baertsch, Andy Pohl, Todd M Lowe	Kevin L Schneider	Todd M Lowe	Biomolecular Engineering, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA.	NA
van der Laan MJ, Dudoit S, Pollard KS	Augmentation procedures for control of the generalized family-wise error rate and tail probabilities for the proportion of false positives.	Stat Appl Genet Mol Biol	3:Article15	2004	16646793		Mark J van der Laan, Sandrine Dudoit, Katherine S Pollard	Mark J van der Laan	Katherine S Pollard	Division of Biostatistics, School of Public Health, University of California, Berkeley, USA. laan@stat.berkeley.edu	NA
van der Laan MJ, Dudoit S, Pollard KS	Multiple testing. Part II. Step-down procedures for control of the family-wise error rate.	Stat Appl Genet Mol Biol	3:Article14	2004	16646792		Mark J van der Laan, Sandrine Dudoit, Katherine S Pollard	Mark J van der Laan	Katherine S Pollard	Division of Biostatistics, School of Public Health, University of California, Berkeley, USA. laan@stat.berkeley.edu	NA
Dudoit S, van der Laan MJ, Pollard KS	Multiple testing. Part I. Single-step procedures for control of general type I error rates.	Stat Appl Genet Mol Biol	3:Article13	2004	16646791		Sandrine Dudoit, Mark J van der Laan, Katherine S Pollard	Sandrine Dudoit	Katherine S Pollard	Division of Biostatistics, School of Public Health, University of California, Berkeley, USA. sandrine@stat.berkeley.edu	NA
Pollard KS, van der Laan MJ	Statistical inference for simultaneous clustering of gene expression data.	Math Biosci	176:1:99-121	2002	11867086		Katherine S Pollard, Mark J van der Laan	Katherine S Pollard	Mark J van der Laan	Division of Biostatistics, School of Public Health, University of California, Earl Warren Hall #7360, Berkeley, CA 94720-7360, USA.	NA
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H	Response to Comment on "Drug Screening for ALS Using Patient-Specific Induced Pluripotent Stem Cells".	Sci Transl Med	5:188:188lr2	2013	23740898		Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita, Motoko Naitoh, Kazutoshi Takahashi, Takuya Yamamoto, Fumihiko Adachi, Takayuki Kondo, Keisuke Okita, Isao Asaka, Takashi Aoi, Akira Watanabe, Yasuhiro Yamada, Asuka Morizane, Jun Takahashi, Takashi Ayaki, Hidefumi Ito, Katsuhiro Yoshikawa, Satoko Yamawaki, Shigehiko Suzuki, Dai Watanabe, Hiroyuki Hioki, Takeshi Kaneko, Kouki Makioka, Koichi Okamoto, Hiroshi Takuma, Akira Tamaoka, Kazuko Hasegawa, Takashi Nonaka, Masato Hasegawa, Akihiro Kawata, Minoru Yoshida, Tatsutoshi Nakahata, Ryosuke Takahashi, Maria C N Marchetto, Fred H Gage, Shinya Yamanaka, Haruhisa Inoue	Naohiro Egawa	Haruhisa Inoue	Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.	NA
Takahashi K, Yamanaka S	Induced pluripotent stem cells in medicine and biology.	Development	140:12:2457-61	2013	23715538		Kazutoshi Takahashi, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan.	NA
Kaneko S, Yamanaka S	To be immunogenic, or not to be: that's the iPSC question.	Cell Stem Cell	12:4:385-6	2013	23561437		Shin Kaneko, Shinya Yamanaka	Shin Kaneko	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan. kaneko.shin@cira.kyoto-u.ac.jp	NA
Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Watanabe A, Goshima N, Yamanaka S	An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells.	Stem Cells	31:3:458-66	2013	23193063		Keisuke Okita, Tatsuya Yamakawa, Yasuko Matsumura, Yoshiko Sato, Naoki Amano, Akira Watanabe, Naoki Goshima, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Department of Reprogramming Science, Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan. okita-g@cira.kyoto-u.ac.jp	NA
Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H	Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness.	Cell Stem Cell	12:4:487-96	2013	23434393		Takayuki Kondo, Masashi Asai, Kayoko Tsukita, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Keiko Imamura, Naohiro Egawa, Naoki Yahata, Keisuke Okita, Kazutoshi Takahashi, Isao Asaka, Takashi Aoi, Akira Watanabe, Kaori Watanabe, Chie Kadoya, Rie Nakano, Dai Watanabe, Kei Maruyama, Osamu Hori, Satoshi Hibino, Tominari Choshi, Tatsutoshi Nakahata, Hiroyuki Hioki, Takeshi Kaneko, Motoko Naitoh, Katsuhiro Yoshikawa, Satoko Yamawaki, Shigehiko Suzuki, Ryuji Hata, Shu-Ichi Ueno, Tsuneyoshi Seki, Kazuhiro Kobayashi, Tatsushi Toda, Kazuma Murakami, Kazuhiro Irie, William L Klein, Hiroshi Mori, Takashi Asada, Ryosuke Takahashi, Nobuhisa Iwata, Shinya Yamanaka, Haruhisa Inoue	Takayuki Kondo	Haruhisa Inoue	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan.	NA
Kamakura T, Makiyama T, Sasaki K, Yoshida Y, Wuriyanghai Y, Chen J, Hattori T, Ohno S, Kita T, Horie M, Yamanaka S, Kimura T	Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture.	Circ. J.	77:5:1307-14	2013	23400258		Tsukasa Kamakura, Takeru Makiyama, Kenichi Sasaki, Yoshinori Yoshida, Yimin Wuriyanghai, Jiarong Chen, Tetsuhisa Hattori, Seiko Ohno, Toru Kita, Minoru Horie, Shinya Yamanaka, Takeshi Kimura	Tsukasa Kamakura	Takeshi Kimura	Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.	NA
Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura K	Steps toward safe cell therapy using induced pluripotent stem cells.	Circ. Res.	112:3:523-33	2013	23371901		Hideyuki Okano, Masaya Nakamura, Kenji Yoshida, Yohei Okada, Osahiko Tsuji, Satoshi Nori, Eiji Ikeda, Shinya Yamanaka, Kyoko Miura	Hideyuki Okano	Kyoko Miura	Department of Physiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan. hidokano@a2.keio.jp	NA
Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K	Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells.	Nat Commun	4:1367	2013	23340407		Shin-Ichi Mae, Akemi Shono, Fumihiko Shiota, Tetsuhiko Yasuno, Masatoshi Kajiwara, Nanaka Gotoda-Nishimura, Sayaka Arai, Aiko Sato-Otubo, Taro Toyoda, Kazutoshi Takahashi, Naoki Nakayama, Chad A Cowan, Takashi Aoi, Seishi Ogawa, Andrew P McMahon, Shinya Yamanaka, Kenji Osafune	Shin-Ichi Mae	Kenji Osafune	Center for iPS Cell Research and Application, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.	NIDDK NIH HHS; DK054364
Veraitch O, Kobayashi T, Imaizumi Y, Akamatsu W, Sasaki T, Yamanaka S, Amagai M, Okano H, Ohyama M	Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo.	J. Invest. Dermatol.	133:6:1479-88	2013	23321923		Ophelia Veraitch, Tetsuro Kobayashi, Yoichi Imaizumi, Wado Akamatsu, Takashi Sasaki, Shinya Yamanaka, Masayuki Amagai, Hideyuki Okano, Manabu Ohyama	Ophelia Veraitch	Manabu Ohyama	Department of Dermatology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan.	NA
Yamana R, Iwasaki M, Wakabayashi M, Nakagawa M, Yamanaka S, Ishihama Y	Rapid and deep profiling of human induced pluripotent stem cell proteome by one-shot NanoLC-MS/MS analysis with meter-scale monolithic silica columns.	J. Proteome Res.	12:1:214-21	2013	23210603		Ryota Yamana, Mio Iwasaki, Masaki Wakabayashi, Masato Nakagawa, Shinya Yamanaka, Yasushi Ishihama	Ryota Yamana	Yasushi Ishihama	Department of Molecular & Cellular BioAnalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.	NA
Fujishiro SH, Nakano K, Mizukami Y, Azami T, Arai Y, Matsunari H, Ishino R, Nishimura T, Watanabe M, Abe T, Furukawa Y, Umeyama K, Yamanaka S, Ema M, Nagashima H, Hanazono Y	Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development.	Stem Cells Dev.	22:3:473-82	2013	22889279		Shuh-hei Fujishiro, Kazuaki Nakano, Yoshihisa Mizukami, Takuya Azami, Yoshikazu Arai, Hitomi Matsunari, Rikiya Ishino, Takashi Nishimura, Masahito Watanabe, Tomoyuki Abe, Yutaka Furukawa, Kazuhiro Umeyama, Shinya Yamanaka, Masatsugu Ema, Hiroshi Nagashima, Yutaka Hanazono	Shuh-hei Fujishiro	Yutaka Hanazono	Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.	NA
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H	Drug screening for ALS using patient-specific induced pluripotent stem cells.	Sci Transl Med	4:145:145ra104	2012	22855461		Naohiro Egawa, Shiho Kitaoka, Kayoko Tsukita, Motoko Naitoh, Kazutoshi Takahashi, Takuya Yamamoto, Fumihiko Adachi, Takayuki Kondo, Keisuke Okita, Isao Asaka, Takashi Aoi, Akira Watanabe, Yasuhiro Yamada, Asuka Morizane, Jun Takahashi, Takashi Ayaki, Hidefumi Ito, Katsuhiro Yoshikawa, Satoko Yamawaki, Shigehiko Suzuki, Dai Watanabe, Hiroyuki Hioki, Takeshi Kaneko, Kouki Makioka, Koichi Okamoto, Hiroshi Takuma, Akira Tamaoka, Kazuko Hasegawa, Takashi Nonaka, Masato Hasegawa, Akihiro Kawata, Minoru Yoshida, Tatsutoshi Nakahata, Ryosuke Takahashi, Maria C N Marchetto, Fred H Gage, Shinya Yamanaka, Haruhisa Inoue	Naohiro Egawa	Haruhisa Inoue	Center for iPS Cell Research and Application-CiRA, Kyoto University, Kyoto 606-8507, Japan.	NA
Kajiwara M, Aoi T, Okita K, Takahashi R, Inoue H, Takayama N, Endo H, Eto K, Toguchida J, Uemoto S, Yamanaka S	Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.	Proc. Natl. Acad. Sci. U.S.A.	109:31:12538-43	2012	22802639		Masatoshi Kajiwara, Takashi Aoi, Keisuke Okita, Ryosuke Takahashi, Haruhisa Inoue, Naoya Takayama, Hiroshi Endo, Koji Eto, Junya Toguchida, Shinji Uemoto, Shinya Yamanaka	Masatoshi Kajiwara	Shinya Yamanaka	Center for Induced Pluripotent Stem Cell Research and Application, Department of Surgery, Graduate School of Medicine, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ogawa S, Asaka I, Heike T, Yamanaka S, Nakahata T, Saito MK	Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery.	Blood	120:6:1299-308	2012	22723549		Takayuki Tanaka, Kazutoshi Takahashi, Mayu Yamane, Shota Tomida, Saori Nakamura, Koichi Oshima, Akira Niwa, Ryuta Nishikomori, Naotomo Kambe, Hideki Hara, Masao Mitsuyama, Nobuhiro Morone, John E Heuser, Takuya Yamamoto, Akira Watanabe, Aiko Sato-Otsubo, Seishi Ogawa, Isao Asaka, Toshio Heike, Shinya Yamanaka, Tatsutoshi Nakahata, Megumu K Saito	Takayuki Tanaka	Megumu K Saito	Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.	NA
Yamanaka S	Induced pluripotent stem cells: past, present, and future.	Cell Stem Cell	10:6:678-84	2012	22704507		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan. yamanaka@cira.kyoto-u.ac.jp	NA
Blanpain C, Daley GQ, Hochedlinger K, Passegué E, Rossant J, Yamanaka S	Stem cells assessed.	Nat. Rev. Mol. Cell Biol.	13:7:471-6	2012	22678486		Cédric Blanpain, George Q Daley, Konrad Hochedlinger, Emmanuelle Passegué, Janet Rossant, Shinya Yamanaka	Cédric Blanpain	Shinya Yamanaka	Walloon Excellence in Life Science and Biotechnology, Interdisciplinary Research Institute, Université Libre de Bruxelles, 808, route de Lennik, BatC, C6-130, 1070 Brussels, Belgium. Cedric.Blanpain@ulb.ac.be	NA
Hayashi Y, Saitou M, Yamanaka S	Germline development from human pluripotent stem cells toward disease modeling of infertility.	Fertil. Steril.	97:6:1250-9	2012	22656305		Yohei Hayashi, Mitinori Saitou, Shinya Yamanaka	Yohei Hayashi	Shinya Yamanaka	Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA. yhayashi@gladstone.ucsf.edu	NA
Miki K, Uenaka H, Saito A, Miyagawa S, Sakaguchi T, Higuchi T, Shimizu T, Okano T, Yamanaka S, Sawa Y	Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats.	Stem Cells Transl Med	1:5:430-7	2012	23197822		Kenji Miki, Hisazumi Uenaka, Atsuhiro Saito, Shigeru Miyagawa, Taichi Sakaguchi, Takahiro Higuchi, Tatsuya Shimizu, Teruo Okano, Shinya Yamanaka, Yoshiki Sawa	Kenji Miki	Yoshiki Sawa	Department of Surgery, Division of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.	NA
Sakurai H, Yamanaka S	[Research for cell therapy by induced pluripotent stem cell].	Nippon Rinsho	69:12:2114-8	2011	22242307		Hidetoshi Sakurai, Shinya Yamanaka	Hidetoshi Sakurai	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Kyoto University.	NA
Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H, Baker J, Baker D, Munoz MB, Beil S, Benvenisty N, Ben-Yosef D, Biancotti JC, Bosman A, Brena RM, Brison D, Caisander G, Camarasa MV, Chen J, Chiao E, Choi YM, Choo AB, Collins D, Colman A, Crook JM, Daley GQ, Dalton A, De Sousa PA, Denning C, Downie J, Dvorak P, Montgomery KD, Feki A, Ford A, Fox V, Fraga AM, Frumkin T, Ge L, Gokhale PJ, Golan-Lev T, Gourabi H, Gropp M, Lu G, Hampl A, Harron K, Healy L, Herath W, Holm F, Hovatta O, Hyllner J, Inamdar MS, Irwanto AK, Ishii T, Jaconi M, Jin Y, Kimber S, Kiselev S, Knowles BB, Kopper O, Kukharenko V, Kuliev A, Lagarkova MA, Laird PW, Lako M, Laslett AL, Lavon N, Lee DR, Lee JE, Li C, Lim LS, Ludwig TE, Ma Y, Maltby E, Mateizel I, Mayshar Y, Mileikovsky M, Minger SL, Miyazaki T, Moon SY, Moore H, Mummery C, Nagy A, Nakatsuji N, Narwani K, Oh SK, Oh SK, Olson C, Otonkoski T, Pan F, Park IH, Pells S, Pera MF, Pereira LV, Qi O, Raj GS, Reubinoff B, Robins A, Robson P, Rossant J, Salekdeh GH, Schulz TC, Sermon K, Sheik Mohamed J, Shen H, Sherrer E, Sidhu K, Sivarajah S, Skottman H, Spits C, Stacey GN, Strehl R, Strelchenko N, Suemori H, Sun B, Suuronen R, Takahashi K, Tuuri T, Venu P, Verlinsky Y, Ward-van Oostwaard D, Weisenberger DJ, Wu Y, Yamanaka S, Young L, Zhou Q	Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage.	Nat. Biotechnol.	29:12:1132-44	2011	22119741		Katherine Amps, Peter W Andrews, George Anyfantis, Lyle Armstrong, Stuart Avery, Hossein Baharvand, Julie Baker, Duncan Baker, Maria B Munoz, Stephen Beil, Nissim Benvenisty, Dalit Ben-Yosef, Juan-Carlos Biancotti, Alexis Bosman, Romulo Martin Brena, Daniel Brison, Gunilla Caisander, María V Camarasa, Jieming Chen, Eric Chiao, Young Min Choi, Andre B H Choo, Daniel Collins, Alan Colman, Jeremy M Crook, George Q Daley, Anne Dalton, Paul A De Sousa, Chris Denning, Janet Downie, Petr Dvorak, Karen D Montgomery, Anis Feki, Angela Ford, Victoria Fox, Ana M Fraga, Tzvia Frumkin, Lin Ge, Paul J Gokhale, Tamar Golan-Lev, Hamid Gourabi, Michal Gropp, Guangxiu Lu, Ales Hampl, Katie Harron, Lyn Healy, Wishva Herath, Frida Holm, Outi Hovatta, Johan Hyllner, Maneesha S Inamdar, Astrid Kresentia Irwanto, Tetsuya Ishii, Marisa Jaconi, Ying Jin, Susan Kimber, Sergey Kiselev, Barbara B Knowles, Oded Kopper, Valeri Kukharenko, Anver Kuliev, Maria A Lagarkova, Peter W Laird, Majlinda Lako, Andrew L Laslett, Neta Lavon, Dong Ryul Lee, Jeoung Eun Lee, Chunliang Li, Linda S Lim, Tenneille E Ludwig, Yu Ma, Edna Maltby, Ileana Mateizel, Yoav Mayshar, Maria Mileikovsky, Stephen L Minger, Takamichi Miyazaki, Shin Yong Moon, Harry Moore, Christine Mummery, Andras Nagy, Norio Nakatsuji, Kavita Narwani, Steve K W Oh, Sun Kyung Oh, Cia Olson, Timo Otonkoski, Fei Pan, In-Hyun Park, Steve Pells, Martin F Pera, Lygia V Pereira, Ouyang Qi, Grace Selva Raj, Benjamin Reubinoff, Alan Robins, Paul Robson, Janet Rossant, Ghasem H Salekdeh, Thomas C Schulz, Karen Sermon, Jameelah Sheik Mohamed, Hui Shen, Eric Sherrer, Kuldip Sidhu, Shirani Sivarajah, Heli Skottman, Claudia Spits, Glyn N Stacey, Raimund Strehl, Nick Strelchenko, Hirofumi Suemori, Bowen Sun, Riitta Suuronen, Kazutoshi Takahashi, Timo Tuuri, Parvathy Venu, Yuri Verlinsky, Dorien Ward-van Oostwaard, Daniel J Weisenberger, Yue Wu, Shinya Yamanaka, Lorraine Young, Qi Zhou	Katherine Amps	Qi Zhou	Centre for Stem Cell Biology, Department of Biomedical Science, The University of Sheffield, Sheffield, UK.	Medical Research Council; 
Hiratsuka M, Uno N, Ueda K, Kurosaki H, Imaoka N, Kazuki K, Ueno E, Akakura Y, Katoh M, Osaki M, Kazuki Y, Nakagawa M, Yamanaka S, Oshimura M	Integration-free iPS cells engineered using human artificial chromosome vectors.	PLoS ONE	6:10:e25961	2011	21998730		Masaharu Hiratsuka, Narumi Uno, Kana Ueda, Hajime Kurosaki, Natsuko Imaoka, Kanako Kazuki, Etsuya Ueno, Yutaro Akakura, Motonobu Katoh, Mitsuhiko Osaki, Yasuhiro Kazuki, Masato Nakagawa, Shinya Yamanaka, Mitsuo Oshimura	Masaharu Hiratsuka	Mitsuo Oshimura	Division of Molecular and Cell Genetics, Department of Molecular and Cellular Biology, School of Life Sciences, Faculty of Medicine, Tottori University, Yonago, Japan.	NA
Yahata N, Asai M, Kitaoka S, Takahashi K, Asaka I, Hioki H, Kaneko T, Maruyama K, Saido TC, Nakahata T, Asada T, Yamanaka S, Iwata N, Inoue H	Anti-Aβ drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease.	PLoS ONE	6:9:e25788	2011	21984949		Naoki Yahata, Masashi Asai, Shiho Kitaoka, Kazutoshi Takahashi, Isao Asaka, Hiroyuki Hioki, Takeshi Kaneko, Kei Maruyama, Takaomi C Saido, Tatsutoshi Nakahata, Takashi Asada, Shinya Yamanaka, Nobuhisa Iwata, Haruhisa Inoue	Naoki Yahata	Haruhisa Inoue	Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.	NA
Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H	Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice.	Proc. Natl. Acad. Sci. U.S.A.	108:40:16825-30	2011	21949375		Satoshi Nori, Yohei Okada, Akimasa Yasuda, Osahiko Tsuji, Yuichiro Takahashi, Yoshiomi Kobayashi, Kanehiro Fujiyoshi, Masato Koike, Yasuo Uchiyama, Eiji Ikeda, Yoshiaki Toyama, Shinya Yamanaka, Masaya Nakamura, Hideyuki Okano	Satoshi Nori	Hideyuki Okano	Department of Physiology, School of Medicine, Keio University, Shinjuku, Tokyo 160-8582, Japan.	NA
Okita K, Nagata N, Yamanaka S	Immunogenicity of induced pluripotent stem cells.	Circ. Res.	109:7:720-1	2011	21921270		Keisuke Okita, Naoki Nagata, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan.	NA
Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N	Modeling familial Alzheimer's disease with induced pluripotent stem cells.	Hum. Mol. Genet.	20:23:4530-9	2011	21900357		Takuya Yagi, Daisuke Ito, Yohei Okada, Wado Akamatsu, Yoshihiro Nihei, Takahito Yoshizaki, Shinya Yamanaka, Hideyuki Okano, Norihiro Suzuki	Takuya Yagi	Norihiro Suzuki	Department of Neurology, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.	NA
Wang YC, Nakagawa M, Garitaonandia I, Slavin I, Altun G, Lacharite RM, Nazor KL, Tran HT, Lynch CL, Leonardo TR, Liu Y, Peterson SE, Laurent LC, Yamanaka S, Loring JF	Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis.	Cell Res.	21:11:1551-63	2011	21894191		Yu-Chieh Wang, Masato Nakagawa, Ibon Garitaonandia, Ileana Slavin, Gulsah Altun, Robert M Lacharite, Kristopher L Nazor, Ha T Tran, Candace L Lynch, Trevor R Leonardo, Ying Liu, Suzanne E Peterson, Louise C Laurent, Shinya Yamanaka, Jeanne F Loring	Yu-Chieh Wang	Jeanne F Loring	The Scripps Research Institute, Department of Chemical Physiology, La Jolla, CA 92037, USA.	NIMH NIH HHS; R21 MH087925
Nakamura T, Nakagawa M, Ichisaka T, Shiota A, Yamanaka S	Essential roles of ECAT15-2/Dppa2 in functional lung development.	Mol. Cell. Biol.	31:21:4366-78	2011	21896782		Tomonori Nakamura, Masato Nakagawa, Tomoko Ichisaka, Arufumi Shiota, Shinya Yamanaka	Tomonori Nakamura	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan.	NA
Uosaki H, Fukushima H, Takeuchi A, Matsuoka S, Nakatsuji N, Yamanaka S, Yamashita JK	Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression.	PLoS ONE	6:8:e23657	2011	21876760		Hideki Uosaki, Hiroyuki Fukushima, Ayako Takeuchi, Satoshi Matsuoka, Norio Nakatsuji, Shinya Yamanaka, Jun K Yamashita	Hideki Uosaki	Jun K Yamashita	Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.	NA
Okita K, Yamanaka S	Induced pluripotent stem cells: opportunities and challenges.	Philos. Trans. R. Soc. Lond., B, Biol. Sci.	366:1575:2198-207	2011	21727125		Keisuke Okita, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan.	NA
Higashi H, Brüstle O, Daley GQ, Yamanaka S	The nomenclature system should be sustainable, but also practical.	Cell Stem Cell	8:6:606-7	2011	21624802		Hiroyuki Higashi, Oliver Brüstle, George Q Daley, Shinya Yamanaka	Hiroyuki Higashi	Shinya Yamanaka		NA
Iwabuchi KA, Yamakawa T, Sato Y, Ichisaka T, Takahashi K, Okita K, Yamanaka S	ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency.	PLoS ONE	6:5:e20461	2011	21637830		Kumiko A Iwabuchi, Tatsuya Yamakawa, Yoshiko Sato, Tomoko Ichisaka, Kazutoshi Takahashi, Keisuke Okita, Shinya Yamanaka	Kumiko A Iwabuchi	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.	NA
Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka K, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S	A more efficient method to generate integration-free human iPS cells.	Nat. Methods	8:5:409-12	2011	21460823		Keisuke Okita, Yasuko Matsumura, Yoshiko Sato, Aki Okada, Asuka Morizane, Satoshi Okamoto, Hyenjong Hong, Masato Nakagawa, Koji Tanabe, Ken-ichi Tezuka, Toshiyuki Shibata, Takahiro Kunisada, Masayo Takahashi, Jun Takahashi, Hiroh Saji, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan. okita@cira.kyoto-u.ac.jp	NA
Fujiwara M, Yan P, Otsuji TG, Narazaki G, Uosaki H, Fukushima H, Kuwahara K, Harada M, Matsuda H, Matsuoka S, Okita K, Takahashi K, Nakagawa M, Ikeda T, Sakata R, Mummery CL, Nakatsuji N, Yamanaka S, Nakao K, Yamashita JK	Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A.	PLoS ONE	6:2:e16734	2011	21364991		Masataka Fujiwara, Peishi Yan, Tomomi G Otsuji, Genta Narazaki, Hideki Uosaki, Hiroyuki Fukushima, Koichiro Kuwahara, Masaki Harada, Hiroyuki Matsuda, Satoshi Matsuoka, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Tadashi Ikeda, Ryuzo Sakata, Christine L Mummery, Norio Nakatsuji, Shinya Yamanaka, Kazuwa Nakao, Jun K Yamashita	Masataka Fujiwara	Jun K Yamashita	Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan.	NA
Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y	Generation of human melanocytes from induced pluripotent stem cells.	PLoS ONE	6:1:e16182	2011	21249204		Shigeki Ohta, Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Reiko Kuwahara, Manabu Ohyama, Masayuki Amagai, Yumi Matsuzaki, Shinya Yamanaka, Hideyuki Okano, Yutaka Kawakami	Shigeki Ohta	Yutaka Kawakami	Division of Cellular Signaling, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan.	NA
Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K	Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells.	J. Exp. Med.	207:13:2817-30	2010	21098095		Naoya Takayama, Satoshi Nishimura, Sou Nakamura, Takafumi Shimizu, Ryoko Ohnishi, Hiroshi Endo, Tomoyuki Yamaguchi, Makoto Otsu, Ken Nishimura, Mahito Nakanishi, Akira Sawaguchi, Ryozo Nagai, Kazutoshi Takahashi, Shinya Yamanaka, Hiromitsu Nakauchi, Koji Eto	Naoya Takayama	Koji Eto	Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, the Institute of Medical Science, Tokyo, Japan.	NA
Nakahata T, Awaya T, Chang H, Mizuno Y, Niwa A, Fukada S, Takeda S, Yamanaka S, Heike T	Derivation of engraftable myogenic precursors from murine ES/iPS cells and generation of disease-specific iPS cells from patients with Duchenne muscular dystrophy (DMD) and other diseases.	Rinsho Shinkeigaku	50:11:889	2010	21921492		Tatsutoshi Nakahata, Tomonari Awaya, Hsi Chang, Yuta Mizuno, Akira Niwa, So-ichiro Fukada, Shin'ichi Takeda, Shinya Yamanaka, Toshio Heike	Tatsutoshi Nakahata	Toshio Heike	Department of Pediatrics, Graduate School of Medicine, Osaka University, Osaka, Japan.	NA
Yoshida Y, Yamanaka S	iPS cells: a source of cardiac regeneration.	J. Mol. Cell. Cardiol.	50:2:327-32	2011	21040726		Yoshinori Yoshida, Shinya Yamanaka	Yoshinori Yoshida	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Sakyo-ku, Kyoto, Japan. yoshinor@cira.kyoto-u.ac.jp	NA
Egusa H, Okita K, Kayashima H, Yu G, Fukuyasu S, Saeki M, Matsumoto T, Yamanaka S, Yatani H	Gingival fibroblasts as a promising source of induced pluripotent stem cells.	PLoS ONE	5:9:e12743	2010	20856871		Hiroshi Egusa, Keisuke Okita, Hiroki Kayashima, Guannan Yu, Sho Fukuyasu, Makio Saeki, Takuya Matsumoto, Shinya Yamanaka, Hirofumi Yatani	Hiroshi Egusa	Hirofumi Yatani	Department of Fixed Prosthodontics, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan. egu@dent.osaka-u.ac.jp	NA
Imamura M, Aoi T, Tokumasu A, Mise N, Abe K, Yamanaka S, Noce T	Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes.	Mol. Reprod. Dev.	77:9:802-11	2010	20722049		Masanori Imamura, Takashi Aoi, Ako Tokumasu, Nathan Mise, Kuniya Abe, Shinya Yamanaka, Toshiaki Noce	Masanori Imamura	Toshiaki Noce	Mitsubishi Kagaku Institute of Life Sciences, Tokyo, Japan. imamura@a5.keio.jp	NA
Espejel S, Roll GR, McLaughlin KJ, Lee AY, Zhang JY, Laird DJ, Okita K, Yamanaka S, Willenbring H	Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice.	J. Clin. Invest.	120:9:3120-6	2010	20739754		Silvia Espejel, Garrett R Roll, K John McLaughlin, Andrew Y Lee, Jenny Y Zhang, Diana J Laird, Keisuke Okita, Shinya Yamanaka, Holger Willenbring	Silvia Espejel	Holger Willenbring	Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California 94143, USA.	NIDDK NIH HHS; R01 DK080852-05
Nakagawa M, Takizawa N, Narita M, Ichisaka T, Yamanaka S	Promotion of direct reprogramming by transformation-deficient Myc.	Proc. Natl. Acad. Sci. U.S.A.	107:32:14152-7	2010	20660764		Masato Nakagawa, Nanako Takizawa, Megumi Narita, Tomoko Ichisaka, Shinya Yamanaka	Masato Nakagawa	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan. nakagawa@cira.kyoto-u.ac.jp	NHLBI NIH HHS; U01 HL100406
Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, Yuzaki M, Ikeda E, Toyama Y, Nakamura M, Yamanaka S, Okano H	Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury.	Proc. Natl. Acad. Sci. U.S.A.	107:28:12704-9	2010	20615974		Osahiko Tsuji, Kyoko Miura, Yohei Okada, Kanehiro Fujiyoshi, Masahiko Mukaino, Narihito Nagoshi, Kazuya Kitamura, Gentaro Kumagai, Makoto Nishino, Shuta Tomisato, Hisanobu Higashi, Toshihiro Nagai, Hiroyuki Katoh, Kazuhisa Kohda, Yumi Matsuzaki, Michisuke Yuzaki, Eiji Ikeda, Yoshiaki Toyama, Masaya Nakamura, Shinya Yamanaka, Hideyuki Okano	Osahiko Tsuji	Hideyuki Okano	Department of Physiology, School of Medicine, Keio University, Shinjuku, Tokyo 160-8582, Japan.	NA
Yoshida Y, Yamanaka S	Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration.	Circulation	122:1:80-7	2010	20606130		Yoshinori Yoshida, Shinya Yamanaka	Yoshinori Yoshida	Shinya Yamanaka	Institute for Integrated Cell-Material Sciences, Kyoto University, Japan.	NA
Yamanaka S	Patient-specific pluripotent stem cells become even more accessible.	Cell Stem Cell	7:1:1-2	2010	20621038		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan. yamanaka@cira.kyoto-u.ac.jp	NA
Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E	miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues.	Aging (Albany NY)	2:7:415-31	2010	20634564		Laura R Saunders, Amar Deep Sharma, Jaime Tawney, Masato Nakagawa, Keisuke Okita, Shinya Yamanaka, Holger Willenbring, Eric Verdin	Laura R Saunders	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, 94158, USA.	NHLBI NIH HHS; U01 HL100406
Kaichi S, Hasegawa K, Takaya T, Yokoo N, Mima T, Kawamura T, Morimoto T, Ono K, Baba S, Doi H, Yamanaka S, Nakahata T, Heike T	Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice.	Cardiovasc. Res.	88:2:314-23	2010	20547733		Shinji Kaichi, Koji Hasegawa, Tomohide Takaya, Noritaka Yokoo, Takahiro Mima, Teruhisa Kawamura, Tatsuya Morimoto, Koh Ono, Shiro Baba, Hiraku Doi, Shinya Yamanaka, Tatsutoshi Nakahata, Toshio Heike	Shinji Kaichi	Toshio Heike	Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan. koj@kuhp.kyoto-u.ac.jp	NA
Sato S, Yagi S, Arai Y, Hirabayashi K, Hattori N, Iwatani M, Okita K, Ohgane J, Tanaka S, Wakayama T, Yamanaka S, Shiota K	Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells.	Genes Cells	15:6:607-18	2010	20477876		Shinya Sato, Shintaro Yagi, Yoshikazu Arai, Keiji Hirabayashi, Naoko Hattori, Misa Iwatani, Keisuke Okita, Jun Ohgane, Satoshi Tanaka, Teruhiko Wakayama, Shinya Yamanaka, Kunio Shiota	Shinya Sato	Kunio Shiota	Laboratory of Cellular Biochemistry, Department of Animal Resource Sciences/Veterinary Medical Sciences, University of Tokyo, Tokyo 113-8657, Japan.	NA
Okita K, Yamanaka S	Induction of pluripotency by defined factors.	Exp. Cell Res.	316:16:2565-70	2010	20420827		Keisuke Okita, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8507, Japan. okita@cira.kyoto-u.ac.jp	NA
Homma K, Sone M, Taura D, Yamahara K, Suzuki Y, Takahashi K, Sonoyama T, Inuzuka M, Fukunaga Y, Tamura N, Itoh H, Yamanaka S, Nakao K	Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells.	Atherosclerosis	212:1:42-7	2010	20488443		Koichiro Homma, Masakatsu Sone, Daisuke Taura, Kenichi Yamahara, Yutaka Suzuki, Kazutoshi Takahashi, Takuhiro Sonoyama, Megumi Inuzuka, Yasutomo Fukunaga, Naohisa Tamura, Hiroshi Itoh, Shinya Yamanaka, Kazuwa Nakao	Koichiro Homma	Kazuwa Nakao	Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.	NA
Mizuno Y, Chang H, Umeda K, Niwa A, Iwasa T, Awaya T, Fukada S, Yamamoto H, Yamanaka S, Nakahata T, Heike T	Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells.	FASEB J.	24:7:2245-53	2010	20181939		Yuta Mizuno, Hsi Chang, Katsutsugu Umeda, Akira Niwa, Toru Iwasa, Tomonari Awaya, So-ichiro Fukada, Hiroshi Yamamoto, Shinya Yamanaka, Tatsutoshi Nakahata, Toshio Heike	Yuta Mizuno	Toshio Heike	Department of Pediatrics, Graduate School of Medicine, Kyoto University 54 Kawahara-cho, Shogoin, Sakyo-ku Kyoto 606-8507, Japan.	NA
Okita K, Hong H, Takahashi K, Yamanaka S	Generation of mouse-induced pluripotent stem cells with plasmid vectors.	Nat Protoc	5:3:418-28	2010	20203661		Keisuke Okita, Hyenjong Hong, Kazutoshi Takahashi, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan. okita@cira.kyoto-u.ac.jp	NA
Nakagawa M, Yamanaka S	Reprogramming of somatic cells to pluripotency.	Adv. Exp. Med. Biol.	695:215-24	2010	21222208		Masato Nakagawa, Shinya Yamanaka	Masato Nakagawa	Shinya Yamanaka	Center for iPS Research and Application Institute for Integrated Cell-Material Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan, nakagawa@cira.kyoto-u.ac.jp.	NA
Kazuki Y, Hiratsuka M, Takiguchi M, Osaki M, Kajitani N, Hoshiya H, Hiramatsu K, Yoshino T, Kazuki K, Ishihara C, Takehara S, Higaki K, Nakagawa M, Takahashi K, Yamanaka S, Oshimura M	Complete genetic correction of ips cells from Duchenne muscular dystrophy.	Mol. Ther.	18:2:386-93	2010	19997091		Yasuhiro Kazuki, Masaharu Hiratsuka, Masato Takiguchi, Mitsuhiko Osaki, Naoyo Kajitani, Hidetoshi Hoshiya, Kei Hiramatsu, Toko Yoshino, Kanako Kazuki, Chie Ishihara, Shoko Takehara, Katsumi Higaki, Masato Nakagawa, Kazutoshi Takahashi, Shinya Yamanaka, Mitsuo Oshimura	Yasuhiro Kazuki	Mitsuo Oshimura	Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Science, Tottori University, Yonago, Japan.	NA
Takahashi K, Narita M, Yokura M, Ichisaka T, Yamanaka S	Human induced pluripotent stem cells on autologous feeders.	PLoS ONE	4:12:e8067	2009	19956543		Kazutoshi Takahashi, Megumi Narita, Midori Yokura, Tomoko Ichisaka, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Center for iPS cell Research and Application, Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan. takahash@cira.kyoto-u.ac.jp	NA
Nagata S, Toyoda M, Yamaguchi S, Hirano K, Makino H, Nishino K, Miyagawa Y, Okita H, Kiyokawa N, Nakagawa M, Yamanaka S, Akutsu H, Umezawa A, Tada T	Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells.	Genes Cells	14:12:1395-404	2009	19912344		Shogo Nagata, Masashi Toyoda, Shinpei Yamaguchi, Kunio Hirano, Hatsune Makino, Koichiro Nishino, Yoshitaka Miyagawa, Hajime Okita, Nobutaka Kiyokawa, Masato Nakagawa, Shinya Yamanaka, Hidenori Akutsu, Akihiro Umezawa, Takashi Tada	Shogo Nagata	Takashi Tada	Stem Cell Engineering, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.	NA
Niwa A, Umeda K, Chang H, Saito M, Okita K, Takahashi K, Nakagawa M, Yamanaka S, Nakahata T, Heike T	Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors.	J. Cell. Physiol.	221:2:367-77	2009	19562687		Akira Niwa, Katsutsugu Umeda, Hsi Chang, Megumu Saito, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Shinya Yamanaka, Tatsutoshi Nakahata, Toshio Heike	Akira Niwa	Toshio Heike	Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.	NA
Izpisúa Belmonte JC, Ellis J, Hochedlinger K, Yamanaka S	Induced pluripotent stem cells and reprogramming: seeing the science through the hype.	Nat. Rev. Genet.	10:12:878-83	2009	19859062		Juan Carlos Izpisúa Belmonte, James Ellis, Konrad Hochedlinger, Shinya Yamanaka	Juan Carlos Izpisúa Belmonte	Shinya Yamanaka	Center of Regenerative Medicine in Barcelona, Dr Aiguader 88, 08003 Barcelona, Spain. belmonte@salk.edu	NA
Yamanaka S	Ekiden to iPS Cells.	Nat. Med.	15:10:1145-8	2009	19812575		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan. yamanaka@cira.kyoto-u.ac.jp	NA
Nishimura K, Nakagawa T, Ono K, Ogita H, Sakamoto T, Yamamoto N, Okita K, Yamanaka S, Ito J	Transplantation of mouse induced pluripotent stem cells into the cochlea.	Neuroreport	20:14:1250-4	2009	19625987		Koji Nishimura, Takayuki Nakagawa, Kazuya Ono, Hideaki Ogita, Tatsunori Sakamoto, Norio Yamamoto, Keisuke Okita, Shinya Yamanaka, Juichi Ito	Koji Nishimura	Juichi Ito	Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.	NA
Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S	Hypoxia enhances the generation of induced pluripotent stem cells.	Cell Stem Cell	5:3:237-41	2009	19716359		Yoshinori Yoshida, Kazutoshi Takahashi, Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka	Yoshinori Yoshida	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan. yoshinor@frontier.kyoto-u.ac.jp	NA
Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A	Nanog is the gateway to the pluripotent ground state.	Cell	138:4:722-37	2009	19703398		Jose Silva, Jennifer Nichols, Thorold W Theunissen, Ge Guo, Anouk L van Oosten, Ornella Barrandon, Jason Wray, Shinya Yamanaka, Ian Chambers, Austin Smith	Jose Silva	Austin Smith	Wellcome Trust Centre for Stem Cell Research, University of Cambridge, Cambridge CB2 1QR, UK. jcs64@cscr.cam.ac.uk	Wellcome Trust; 
Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K, Yamanaka S	Suppression of induced pluripotent stem cell generation by the p53-p21 pathway.	Nature	460:7259:1132-5	2009	19668191		Hyenjong Hong, Kazutoshi Takahashi, Tomoko Ichisaka, Takashi Aoi, Osami Kanagawa, Masato Nakagawa, Keisuke Okita, Shinya Yamanaka	Hyenjong Hong	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8507, Japan.	NHLBI NIH HHS; U01 HL100406-01
Yokoo N, Baba S, Kaichi S, Niwa A, Mima T, Doi H, Yamanaka S, Nakahata T, Heike T	The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells.	Biochem. Biophys. Res. Commun.	387:3:482-8	2009	19615974		Noritaka Yokoo, Shiro Baba, Shinji Kaichi, Akira Niwa, Takahiro Mima, Hiraku Doi, Shinya Yamanaka, Tatsutoshi Nakahata, Toshio Heike	Noritaka Yokoo	Toshio Heike	Department of Pediatrics, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, Japan.	NA
Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S	Variation in the safety of induced pluripotent stem cell lines.	Nat. Biotechnol.	27:8:743-5	2009	19590502		Kyoko Miura, Yohei Okada, Takashi Aoi, Aki Okada, Kazutoshi Takahashi, Keisuke Okita, Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe, Mari Ohnuki, Daisuke Ogawa, Eiji Ikeda, Hideyuki Okano, Shinya Yamanaka	Kyoko Miura	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto, Japan.	NA
Yamanaka S	Elite and stochastic models for induced pluripotent stem cell generation.	Nature	460:7251:49-52	2009	19571877		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Kyoto University, Kyoto 606-8507, Japan. yamanaka@cira.kyoto-u.ac.jp	NA
Ohnuki M, Takahashi K, Yamanaka S	Generation and characterization of human induced pluripotent stem cells.	Curr Protoc Stem Cell Biol	Chapter 4:Unit 4A.2	2009	19536759		Mari Ohnuki, Kazutoshi Takahashi, Shinya Yamanaka	Mari Ohnuki	Shinya Yamanaka	Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto, Japan.	NA
Tanaka T, Tohyama S, Murata M, Nomura F, Kaneko T, Chen H, Hattori F, Egashira T, Seki T, Ohno Y, Koshimizu U, Yuasa S, Ogawa S, Yamanaka S, Yasuda K, Fukuda K	In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes.	Biochem. Biophys. Res. Commun.	385:4:497-502	2009	19464263		Tomofumi Tanaka, Shugo Tohyama, Mitsushige Murata, Fumimasa Nomura, Tomoyuki Kaneko, Hao Chen, Fumiyuki Hattori, Toru Egashira, Tomohisa Seki, Yohei Ohno, Uichi Koshimizu, Shinsuke Yuasa, Satoshi Ogawa, Shinya Yamanaka, Kenji Yasuda, Keiichi Fukuda	Tomofumi Tanaka	Keiichi Fukuda	Department of Regenerative Medicine and Advanced Cardiac Therapeutics, School of Medicine, Keio University, Tokyo, Japan.	NA
Tsubooka N, Ichisaka T, Okita K, Takahashi K, Nakagawa M, Yamanaka S	Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts.	Genes Cells	14:6:683-94	2009	19476507		Noriko Tsubooka, Tomoko Ichisaka, Keisuke Okita, Kazutoshi Takahashi, Masato Nakagawa, Shinya Yamanaka	Noriko Tsubooka	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Taura D, Sone M, Homma K, Oyamada N, Takahashi K, Tamura N, Yamanaka S, Nakao K	Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report.	Arterioscler. Thromb. Vasc. Biol.	29:7:1100-3	2009	19423866		Daisuke Taura, Masakatsu Sone, Koichiro Homma, Naofumi Oyamada, Kazutoshi Takahashi, Naohisa Tamura, Shinya Yamanaka, Kazuwa Nakao	Daisuke Taura	Kazuwa Nakao	Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Japan.	NA
Senju S, Haruta M, Matsunaga Y, Fukushima S, Ikeda T, Takahashi K, Okita K, Yamanaka S, Nishimura Y	Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells.	Stem Cells	27:5:1021-31	2009	19415766		Satoru Senju, Miwa Haruta, Yusuke Matsunaga, Satoshi Fukushima, Tokunori Ikeda, Kazutoshi Takahashi, Keisuke Okita, Shinya Yamanaka, Yasuharu Nishimura	Satoru Senju	Yasuharu Nishimura	Department of Immunogenetics, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan. senjusat@gpo.kumamoto-u.ac.jp	NA
Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H, Yoshimura N, Takahashi M	Generation of retinal cells from mouse and human induced pluripotent stem cells.	Neurosci. Lett.	458:3:126-31	2009	19379795		Yasuhiko Hirami, Fumitaka Osakada, Kazutoshi Takahashi, Keisuke Okita, Shinya Yamanaka, Hanako Ikeda, Nagahisa Yoshimura, Masayo Takahashi	Yasuhiko Hirami	Masayo Takahashi	Laboratory for Retinal Regeneration, RIKEN Center for Developmental Biology, 2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe 650-0047, Japan.	NA
Yamanaka S	A fresh look at iPS cells.	Cell	137:1:13-7	2009	19345179		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan. yamanaka@frontier.kyoto-u.ac.jp	NA
Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S	Broader implications of defining standards for the pluripotency of iPSCs.	Cell Stem Cell	4:3:200-1; author reply 202	2009	19265657		George Q Daley, M William Lensch, Rudolf Jaenisch, Alex Meissner, Kathrin Plath, Shinya Yamanaka	George Q Daley	Shinya Yamanaka		NCI NIH HHS; R01 CA084198-12
Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, Nakatsuji N, Okano H, Yamanaka S, Nakao K	Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells.	FEBS Lett.	583:6:1029-33	2009	19250937		Daisuke Taura, Michio Noguchi, Masakatsu Sone, Kiminori Hosoda, Eisaku Mori, Yohei Okada, Kazutoshi Takahashi, Koichiro Homma, Naofumi Oyamada, Megumi Inuzuka, Takuhiro Sonoyama, Ken Ebihara, Naohisa Tamura, Hiroshi Itoh, Hirofumi Suemori, Norio Nakatsuji, Hideyuki Okano, Shinya Yamanaka, Kazuwa Nakao	Daisuke Taura	Kazuwa Nakao	Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.	NA
Tanaka Y, Ikeda T, Kishi Y, Masuda S, Shibata H, Takeuchi K, Komura M, Iwanaka T, Muramatsu S, Kondo Y, Takahashi K, Yamanaka S, Hanazono Y	ERas is expressed in primate embryonic stem cells but not related to tumorigenesis.	Cell Transplant	18:4:381-9	2009	19622226		Yujiro Tanaka, Tamako Ikeda, Yukiko Kishi, Shigeo Masuda, Hiroaki Shibata, Kengo Takeuchi, Makoto Komura, Tadashi Iwanaka, Shin-Ichi Muramatsu, Yasushi Kondo, Kazutoshi Takahashi, Shinya Yamanaka, Yutaka Hanazono	Yujiro Tanaka	Yutaka Hanazono	Division of Regenerative Medicine, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan; Department of Pediatric Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.	NA
Aiba K, Nedorezov T, Piao Y, Nishiyama A, Matoba R, Sharova LV, Sharov AA, Yamanaka S, Niwa H, Ko MS	Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells.	DNA Res.	16:1:73-80	2009	19112179		Kazuhiro Aiba, Timur Nedorezov, Yulan Piao, Akira Nishiyama, Ryo Matoba, Lioudmila V Sharova, Alexei A Sharov, Shinya Yamanaka, Hitoshi Niwa, Minoru S H Ko	Kazuhiro Aiba	Minoru S H Ko	Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, NIH, Baltimore, MD 21224, USA.	NIA NIH HHS; Z01 AG000662-07
Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S	Generation of mouse induced pluripotent stem cells without viral vectors.	Science	322:5903:949-53	2008	18845712		Keisuke Okita, Masato Nakagawa, Hong Hyenjong, Tomoko Ichisaka, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Narazaki G, Uosaki H, Teranishi M, Okita K, Kim B, Matsuoka S, Yamanaka S, Yamashita JK	Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells.	Circulation	118:5:498-506	2008	18625891		Genta Narazaki, Hideki Uosaki, Mizue Teranishi, Keisuke Okita, Bongju Kim, Satoshi Matsuoka, Shinya Yamanaka, Jun K Yamashita	Genta Narazaki	Jun K Yamashita	Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Yamanaka S	Pluripotency and nuclear reprogramming.	Philos. Trans. R. Soc. Lond., B, Biol. Sci.	363:1500:2079-87	2008	18375377		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Center for iPS Cell Research & Application, Kyoto University, Kyoto 606-8507, Japan. yamanaka@frontier.kyoto-u.ac.jp	NA
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T, Yamanaka S	Generation of pluripotent stem cells from adult mouse liver and stomach cells.	Science	321:5889:699-702	2008	18276851		Takashi Aoi, Kojiro Yae, Masato Nakagawa, Tomoko Ichisaka, Keisuke Okita, Kazutoshi Takahashi, Tsutomu Chiba, Shinya Yamanaka	Takashi Aoi	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S	Induction of pluripotent stem cells from adult human fibroblasts by defined factors.	Cell	131:5:861-72	2007	18035408		Kazutoshi Takahashi, Koji Tanabe, Mari Ohnuki, Megumi Narita, Tomoko Ichisaka, Kiichiro Tomoda, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S	Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.	Nat. Biotechnol.	26:1:101-6	2008	18059259		Masato Nakagawa, Michiyo Koyanagi, Koji Tanabe, Kazutoshi Takahashi, Tomoko Ichisaka, Takashi Aoi, Keisuke Okita, Yuji Mochiduki, Nanako Takizawa, Shinya Yamanaka	Masato Nakagawa	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S	New advances in iPS cell research do not obviate the need for human embryonic stem cells.	Cell Stem Cell	1:4:367-8	2007	18371375		Insoo Hyun, Konrad Hochedlinger, Rudolf Jaenisch, Shinya Yamanaka	Insoo Hyun	Shinya Yamanaka		NA
Yamanaka S	Strategies and new developments in the generation of patient-specific pluripotent stem cells.	Cell Stem Cell	1:1:39-49	2007	18371333		Shinya Yamanaka	Shinya Yamanaka	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. yamanaka@frontier.kyoto-u.ac.jp	NA
Okita K, Ichisaka T, Yamanaka S	Generation of germline-competent induced pluripotent stem cells.	Nature	448:7151:313-7	2007	17554338		Keisuke Okita, Tomoko Ichisaka, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Takahashi K, Okita K, Nakagawa M, Yamanaka S	Induction of pluripotent stem cells from fibroblast cultures.	Nat Protoc	2:12:3081-9	2007	18079707		Kazutoshi Takahashi, Keisuke Okita, Masato Nakagawa, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-machi, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.	NA
Yamanaka S, Takahashi K	[Induction of pluripotent stem cells from mouse fibroblast cultures].	Tanpakushitsu Kakusan Koso	51:15:2346-51	2006	17154061		Shinya Yamanaka, Kazutoshi Takahashi	Shinya Yamanaka	Kazutoshi Takahashi	yamanaka@frontier.kyoto-u.ac.jp	NA
Takahashi K, Yamanaka S	Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.	Cell	126:4:663-76	2006	16904174		Kazutoshi Takahashi, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Tanaka TS, Lopez de Silanes I, Sharova LV, Akutsu H, Yoshikawa T, Amano H, Yamanaka S, Gorospe M, Ko MS	Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets.	Dev. Growth Differ.	48:6:381-90	2006	16872451		Tetsuya S Tanaka, Isabel Lopez de Silanes, Lioudmila V Sharova, Hidenori Akutsu, Toshiyuki Yoshikawa, Hisayuki Amano, Shinya Yamanaka, Myriam Gorospe, Minoru S H Ko	Tetsuya S Tanaka	Minoru S H Ko	Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA.	NA
Imamura M, Miura K, Iwabuchi K, Ichisaka T, Nakagawa M, Lee J, Kanatsu-Shinohara M, Shinohara T, Yamanaka S	Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells.	BMC Dev. Biol.	6:34	2006	16859545		Masanori Imamura, Kyoko Miura, Kumiko Iwabuchi, Tomoko Ichisaka, Masato Nakagawa, Jiyoung Lee, Mito Kanatsu-Shinohara, Takashi Shinohara, Shinya Yamanaka	Masanori Imamura	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. imamura@frontier.kyoto-u.ac.jp	NA
Amano H, Itakura K, Maruyama M, Ichisaka T, Nakagawa M, Yamanaka S	Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5).	BMC Dev. Biol.	6:11	2006	16504174		Hisayuki Amano, Ken Itakura, Masayoshi Maruyama, Tomoko Ichisaka, Masato Nakagawa, Shinya Yamanaka	Hisayuki Amano	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan. h-amano@molbio.med.osaka-u.ac.jp	NA
Takahashi K, Ichisaka T, Yamanaka S	Identification of genes involved in tumor-like properties of embryonic stem cells.	Methods Mol. Biol.	329:449-58	2006	16846009		Kazutoshi Takahashi, Tomoko Ichisaka, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Laboratory of Animal Molecular Technology Research and Education, Center for Genetic Information, Nara Institute of Sciences and Technology, Nara, Japan.	NA
Okita K, Yamanaka S	Intracellular signaling pathways regulating pluripotency of embryonic stem cells.	Curr Stem Cell Res Ther	1:1:103-11	2006	18220859		Keisuke Okita, Shinya Yamanaka	Keisuke Okita	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Takahashi K, Nakagawa M, Young SG, Yamanaka S	Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway.	J. Biol. Chem.	280:38:32768-74	2005	16046393		Kazutoshi Takahashi, Masato Nakagawa, Stephen G Young, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University and CREST, Japan Science and Technology Agency, Kyoto 606-8507, Japan.	NCI NIH HHS; CA103999-01
Nakagawa M, Yamanaka S	[Mechanism for maintaining pluripotency in embryonic stem cells and inner cell mass].	Tanpakushitsu Kakusan Koso	50:6 Suppl:546-50	2005	15926478		Masato Nakagawa, Shinya Yamanaka	Masato Nakagawa	Shinya Yamanaka	nakamasa@gtc.naist.jp	NA
Maruyama M, Ichisaka T, Nakagawa M, Yamanaka S	Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells.	J. Biol. Chem.	280:26:24371-9	2005	15863505		Masayoshi Maruyama, Tomoko Ichisaka, Masato Nakagawa, Shinya Yamanaka	Masayoshi Maruyama	Shinya Yamanaka	Department of Stem Cell Biology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.	NA
Takahashi K, Maruyama M, Tokuzawa Y, Murakami M, Oda Y, Yoshikane N, Makabe KW, Ichisaka T, Yamanaka S	Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2).	Genomics	85:3:360-71	2005	15718103		Kazutoshi Takahashi, Masayoshi Maruyama, Yoshimi Tokuzawa, Mirei Murakami, Yasuaki Oda, Nami Yoshikane, Kazuhiro W Makabe, Tomoko Ichisaka, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma 8916-5, Nara 630-0101, Japan.	NA
Tomoda K, Yoneda-Kato N, Fukumoto A, Yamanaka S, Kato JY	Multiple functions of Jab1 are required for early embryonic development and growth potential in mice.	J. Biol. Chem.	279:41:43013-8	2004	15299027		Kiichiro Tomoda, Noriko Yoneda-Kato, Akihisa Fukumoto, Shinya Yamanaka, Jun-Ya Kato	Kiichiro Tomoda	Jun-Ya Kato	Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.	NA
Matsuda E, Shigeoka T, Iida R, Yamanaka S, Kawaichi M, Ishida Y	Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis.	Proc. Natl. Acad. Sci. U.S.A.	101:12:4170-4	2004	15010531		Eishou Matsuda, Toshiaki Shigeoka, Ryuji Iida, Shinya Yamanaka, Masashi Kawaichi, Yasumasa Ishida	Eishou Matsuda	Yasumasa Ishida	Division of Gene Function in Animals, Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma-shi, Nara 630-0192, Japan.	NA
Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S	The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells.	Cell	113:5:631-42	2003	12787504		Kaoru Mitsui, Yoshimi Tokuzawa, Hiroaki Itoh, Kohichi Segawa, Mirei Murakami, Kazutoshi Takahashi, Masayoshi Maruyama, Mitsuyo Maeda, Shinya Yamanaka	Kaoru Mitsui	Shinya Yamanaka	Laboratory of Animal Molecular Technology, Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Nara 630-0192, Japan.	NA
Takahashi K, Mitsui K, Yamanaka S	Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.	Nature	423:6939:541-5	2003	12774123		Kazutoshi Takahashi, Kaoru Mitsui, Shinya Yamanaka	Kazutoshi Takahashi	Shinya Yamanaka	Laboratory of Animal Molecular Technology, Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan.	NA
Tokuzawa Y, Kaiho E, Maruyama M, Takahashi K, Mitsui K, Maeda M, Niwa H, Yamanaka S	Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development.	Mol. Cell. Biol.	23:8:2699-708	2003	12665572		Yoshimi Tokuzawa, Eiko Kaiho, Masayoshi Maruyama, Kazutoshi Takahashi, Kaoru Mitsui, Mitsuyo Maeda, Hitoshi Niwa, Shinya Yamanaka	Yoshimi Tokuzawa	Shinya Yamanaka	Laboratory of Animal Molecular Technology, Research and Education Center for Genetic Information, Nara Institute of Science and Technology, Ikoma, Nara 630-0192, Japan.	NA
Qian X, Balestra ME, Yamanaka S, Borén J, Lee I, Innerarity TL	Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors.	Arterioscler. Thromb. Vasc. Biol.	18:6:1013-20	1998	9633945		X Qian, M E Balestra, S Yamanaka, J Borén, I Lee, T L Innerarity	X Qian	T L Innerarity	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94103, USA. xiaobing_qian@quickmail.ucsf.edu	NHLBI NIH HHS; HL47660
Yamanaka S, Poksay KS, Arnold KS, Innerarity TL	A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme.	Genes Dev.	11:3:321-33	1997	9030685		S Yamanaka, K S Poksay, K S Arnold, T L Innerarity	S Yamanaka	T L Innerarity	University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL47660
Yamanaka S, Poksay KS, Driscoll DM, Innerarity TL	Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif.	J. Biol. Chem.	271:19:11506-10	1996	8626710		S Yamanaka, K S Poksay, D M Driscoll, T L Innerarity	S Yamanaka	T L Innerarity	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100, USA.	NHLBI NIH HHS; HL47660
Yamanaka S, Poksay KS, Balestra ME, Zeng GQ, Innerarity TL	Cloning and mutagenesis of the rabbit ApoB mRNA editing protein. A zinc motif is essential for catalytic activity, and noncatalytic auxiliary factor(s) of the editing complex are widely distributed.	J. Biol. Chem.	269:34:21725-34	1994	8063816		S Yamanaka, K S Poksay, M E Balestra, G Q Zeng, T L Innerarity	S Yamanaka	T L Innerarity	Gladstone Institute of Cardiovascular Disease, University of California, San Francisco 94141-9100.	NHLBI NIH HHS; HL47660
Gut P, Verdin E	Rejuvenating SIRT1 Activators.	Cell Metab.	17:5:635-7	2013	23663735		Philipp Gut, Eric Verdin	Philipp Gut	Eric Verdin	Gladstone Institutes, University of California, San Francisco, CA 94158, USA.	NA
Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW	Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.	Proc. Natl. Acad. Sci. U.S.A.	110:16:6601-6	2013	23576753		Matthew J Rardin, John C Newman, Jason M Held, Michael P Cusack, Dylan J Sorensen, Biao Li, Birgit Schilling, Sean D Mooney, C Ronald Kahn, Eric Verdin, Bradford W Gibson	Matthew J Rardin	Bradford W Gibson	Buck Institute for Research on Aging, Novato, CA 94945, USA.	NIA NIH HHS; T32AG000266
Shirakawa K, Chavez L, Hakre S, Calvanese V, Verdin E	Reactivation of latent HIV by histone deacetylase inhibitors.	Trends Microbiol.	21:6:277-85	2013	23517573		Kotaro Shirakawa, Leonard Chavez, Shweta Hakre, Vincenzo Calvanese, Eric Verdin	Kotaro Shirakawa	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA; Department of Medicine, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; U19 AI096113
Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E	The sirtuins, oxidative stress and aging: an emerging link.	Aging (Albany NY)	5:3:144-50	2013	23474711		Philip I Merksamer, Yufei Liu, Wenjuan He, Matthew D Hirschey, Danica Chen, Eric Verdin	Philip I Merksamer	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Sinclair D, Verdin E	The longevity of sirtuins.	Cell Rep	2:6:1473-4	2012	23273894		David Sinclair, Eric Verdin	David Sinclair	Eric Verdin	Glenn Laboratories for the Molecular Biology of Aging, Department of Genetics, Harvard Medical School, Boston, MA 02115, USA. david_sinclair@hms.harvard.edu	NA
Weir HJ, Murray TK, Kehoe PG, Love S, Verdin EM, O'Neill MJ, Lane JD, Balthasar N	CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease.	PLoS ONE	7:11:e48225	2012	23139766		Heather J M Weir, Tracey K Murray, Patrick G Kehoe, Seth Love, Eric M Verdin, Michael J O'Neill, Jon D Lane, Nina Balthasar	Heather J M Weir	Nina Balthasar	School of Biochemistry, University of Bristol, Bristol, United Kingdom.	Biotechnology and Biological Sciences Research Council; 
Kasler HG, Lim HW, Mottet D, Collins AM, Lee IS, Verdin E	Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.	EMBO J.	31:23:4453-65	2012	23103766		Herbert G Kasler, Hyung W Lim, Denis Mottet, Amy M Collins, Intelly S Lee, Eric Verdin	Herbert G Kasler	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Newman JC, He W, Verdin E	Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease.	J. Biol. Chem.	287:51:42436-43	2012	23086951		John C Newman, Wenjuan He, Eric Verdin	John C Newman	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.	NIDDK NIH HHS; R24 DK085610
Bonezzi K, Belotti D, North BJ, Ghilardi C, Borsotti P, Resovi A, Ubezio P, Riva A, Giavazzi R, Verdin E, Taraboletti G	Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies.	Neoplasia	14:9:846-54	2012	23019416		Katiuscia Bonezzi, Dorina Belotti, Brian J North, Carmen Ghilardi, Patrizia Borsotti, Andrea Resovi, Paolo Ubezio, Antonella Riva, Raffaella Giavazzi, Eric Verdin, Giulia Taraboletti	Katiuscia Bonezzi	Giulia Taraboletti	Tumor Angiogenesis Unit, Department of Oncology, Mario Negri Institute for Pharmacological Research, Bergamo, Italy.	NA
Pan Y, Nishida Y, Wang M, Verdin E	Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review.	Gerontology	58:6:524-30	2012	22947849		Yong Pan, Yuya Nishida, Margaret Wang, Eric Verdin	Yong Pan	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA. yong.pan@gladstone.ucsf.edu	NA
He W, Newman JC, Wang MZ, Ho L, Verdin E	Mitochondrial sirtuins: regulators of protein acylation and metabolism.	Trends Endocrinol. Metab.	23:9:467-76	2012	22902903		Wenjuan He, John C Newman, Margaret Z Wang, Linh Ho, Eric Verdin	Wenjuan He	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, CA 94158, USA.	NA
Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H	Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.	Aging Cell	11:5:770-82	2012	22672615		Young C Jang, Yuhong Liu, Christopher R Hayworth, Arunabh Bhattacharya, Michael S Lustgarten, Florian L Muller, Asish Chaudhuri, Wenbo Qi, Yan Li, Jing-Yi Huang, Eric Verdin, Arlan Richardson, Holly Van Remmen	Young C Jang	Holly Van Remmen	Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.	NCI NIH HHS; P30 CA54174
Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, Maldarelli F, Margolis D, Markowitz M, Martinez-Picado J, Mullins JI, Mellors J, Moreno S, O'Doherty U, Palmer S, Penicaud MC, Peterlin M, Poli G, Routy JP, Rouzioux C, Silvestri G, Stevenson M, Telenti A, Van Lint C, Verdin E, Woolfrey A, Zaia J, Barré-Sinoussi F	Towards an HIV cure: a global scientific strategy.	Nat. Rev. Immunol.	12:8:607-14	2012	22814509		Steven G Deeks, Brigitte Autran, Ben Berkhout, Monsef Benkirane, Scott Cairns, Nicolas Chomont, Tae-Wook Chun, Melissa Churchill, Michele Di Mascio, Christine Katlama, Alain Lafeuillade, Alan Landay, Michael Lederman, Sharon R Lewin, Frank Maldarelli, David Margolis, Martin Markowitz, Javier Martinez-Picado, James I Mullins, John Mellors, Santiago Moreno, Una O'Doherty, Sarah Palmer, Marie-Capucine Penicaud, Matija Peterlin, Guido Poli, Jean-Pierre Routy, Christine Rouzioux, Guido Silvestri, Mario Stevenson, Amalio Telenti, Carine Van Lint, Eric Verdin, Ann Woolfrey, John Zaia, Françoise Barré-Sinoussi	Steven G Deeks	Françoise Barré-Sinoussi		NIAID NIH HHS; P30 AI082151
Kamarajan P, Alhazzazi TY, Danciu T, D'silva NJ, Verdin E, Kapila YL	Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis.	Cancer	118:23:5800-10	2012	22674009		Pachiyappan Kamarajan, Turki Y Alhazzazi, Theodora Danciu, Nisha J D'silva, Eric Verdin, Yvonne L Kapila	Pachiyappan Kamarajan	Yvonne L Kapila	Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1078, USA.	NIDCR NIH HHS; R56DE014429
Deeks SG, Verdin E, McCune JM	Immunosenescence and HIV.	Curr. Opin. Immunol.	24:4:501-6	2012	22658763		Steven G Deeks, Eric Verdin, Joseph M McCune	Steven G Deeks	Joseph M McCune	HIV/AIDS Program, Department of Medicine, University of California, San Francisco, CA, USA.	NA
Ismail H, Mofarrahi M, Echavarria R, Harel S, Verdin E, Lim HW, Jin ZG, Sun J, Zeng H, Hussain SN	Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77.	Arterioscler. Thromb. Vasc. Biol.	32:7:1707-16	2012	22628435		Hodan Ismail, Mahroo Mofarrahi, Raquel Echavarria, Sharon Harel, Eric Verdin, Hyung W Lim, Zheng-Gen Jin, Jianxin Sun, Huiyan Zeng, Sabah N A Hussain	Hodan Ismail	Sabah N A Hussain	Critical Care and Respiratory Divisions, Department of Medicine, McGill University Health Centre and Meakins-Christie Laboratories, McGill University, Montréal, Québec, Canada.	Canadian Institutes of Health Research; 
Hakre S, Chavez L, Shirakawa K, Verdin E	HIV latency: experimental systems and molecular models.	FEMS Microbiol. Rev.	36:3:706-16	2012	22372374		Shweta Hakre, Leonard Chavez, Kotaro Shirakawa, Eric Verdin	Shweta Hakre	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94941, USA.	NIAID NIH HHS; U19 AI096113
Schilling B, Rardin MJ, MacLean BX, Zawadzka AM, Frewen BE, Cusack MP, Sorensen DJ, Bereman MS, Jing E, Wu CC, Verdin E, Kahn CR, Maccoss MJ, Gibson BW	Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation.	Mol. Cell Proteomics	11:5:202-14	2012	22454539		Birgit Schilling, Matthew J Rardin, Brendan X MacLean, Anna M Zawadzka, Barbara E Frewen, Michael P Cusack, Dylan J Sorensen, Michael S Bereman, Enxuan Jing, Christine C Wu, Eric Verdin, C Ronald Kahn, Michael J Maccoss, Bradford W Gibson	Birgit Schilling	Bradford W Gibson	Buck Institute for Research on Aging, Novato, California 94945, USA.	NCI NIH HHS; U24 CA126477
Fritz KS, Galligan JJ, Hirschey MD, Verdin E, Petersen DR	Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice.	J. Proteome Res.	11:3:1633-43	2012	22309199		Kristofer S Fritz, James J Galligan, Matthew D Hirschey, Eric Verdin, Dennis R Petersen	Kristofer S Fritz	Dennis R Petersen	Department of Pharmaceutical Sciences, University of Colorado Denver , Aurora, Colorado, United States.	NIAAA NIH HHS; R37AA09300
Kwon HS, Lim HW, Wu J, Schnölzer M, Verdin E, Ott M	Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells.	J. Immunol.	188:6:2712-21	2012	22312127		Hye-Sook Kwon, Hyung W Lim, Jessica Wu, Martina Schnölzer, Eric Verdin, Melanie Ott	Hye-Sook Kwon	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01 AI081651
Peixoto P, Castronovo V, Matheus N, Polese C, Peulen O, Gonzalez A, Boxus M, Verdin E, Thiry M, Dequiedt F, Mottet D	HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells.	Cell Death Differ.	19:7:1239-52	2012	22301920		P Peixoto, V Castronovo, N Matheus, C Polese, O Peulen, A Gonzalez, M Boxus, E Verdin, M Thiry, F Dequiedt, D Mottet	P Peixoto	D Mottet	Metastasis Research Laboratory, University of Liège, Belgium.	NA
Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M	BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism.	Cell Cycle	12:3:452-62	2013	23255218		Daniela Boehm, Vincenzo Calvanese, Roy D Dar, Sifei Xing, Sebastian Schroeder, Laura Martins, Katherine Aull, Pao-Chen Li, Vicente Planelles, James E Bradner, Ming-Ming Zhou, Robert F Siliciano, Leor Weinberger, Eric Verdin, Melanie Ott	Daniela Boehm	Melanie Ott	Gladstone Institute of Virology and Immunology, San Francisco, CA, USA.	NIAID NIH HHS; U19AI096113
Gallastegui E, Marshall B, Vidal D, Sanchez-Duffhues G, Collado JA, Alvarez-Fernández C, Luque N, Terme JM, Gatell JM, Sánchez-Palomino S, Muñoz E, Mestres J, Verdin E, Jordan A	Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1.	J. Virol.	86:7:3795-808	2012	22258251		Edurne Gallastegui, Brett Marshall, David Vidal, Gonzalo Sanchez-Duffhues, Juan A Collado, Carmen Alvarez-Fernández, Neus Luque, Jean-Michel Terme, Josep M Gatell, Sonsoles Sánchez-Palomino, Eduardo Muñoz, Jordi Mestres, Eric Verdin, Albert Jordan	Edurne Gallastegui	Albert Jordan	Institut de Biologia Molecular de Barcelona (IBMB-CSIC), Barcelona, Spaina; Gladstone Institute of Virology and Immunology, San Francisco, California, USA. albert.jordan@ibmb.csic.es	NA
Moury B, Verdin E	Viruses of pepper crops in the Mediterranean basin: a remarkable stasis.	Adv. Virus Res.	84:127-62	2012	22682167		Benoît Moury, Eric Verdin	Benoît Moury	Eric Verdin	INRA, UR407 Pathologie Végétale, Domaine Saint Maurice, Montfavet, France.	NA
Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T	Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.	PLoS Biol.	9:11:e1001206	2011	22140357		Haleh Rafati, Maribel Parra, Shweta Hakre, Yuri Moshkin, Eric Verdin, Tokameh Mahmoudi	Haleh Rafati	Tokameh Mahmoudi	Department of Biochemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.	NIGMS NIH HHS; R01GM51671
Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M	Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes.	J. Biol. Chem.	287:2:1090-9	2012	22084242		Sebastian Schröder, Sungyoo Cho, Lei Zeng, Qiang Zhang, Katrin Kaehlcke, Lily Mak, Joann Lau, Dwayne Bisgrove, Martina Schnölzer, Eric Verdin, Ming-Ming Zhou, Melanie Ott	Sebastian Schröder	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NIAID NIH HHS; R01 AI081651
Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, Dai J, Verdin E, Ye Y, Zhao Y	The first identification of lysine malonylation substrates and its regulatory enzyme.	Mol. Cell Proteomics	10:12:M111.012658	2011	21908771		Chao Peng, Zhike Lu, Zhongyu Xie, Zhongyi Cheng, Yue Chen, Minjia Tan, Hao Luo, Yi Zhang, Wendy He, Ke Yang, Bernadette M M Zwaans, Daniel Tishkoff, Linh Ho, David Lombard, Tong-Chuan He, Junbiao Dai, Eric Verdin, Yang Ye, Yingming Zhao	Chao Peng	Yingming Zhao	Ben May Department for Cancer Research, The University of Chicago, Chicago, IL 60637, USA.	NIA NIH HHS; T32-AG000114
Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR	Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production.	Proc. Natl. Acad. Sci. U.S.A.	108:35:14608-13	2011	21873205		Enxuan Jing, Brice Emanuelli, Matthew D Hirschey, Jeremie Boucher, Kevin Y Lee, David Lombard, Eric M Verdin, C Ronald Kahn	Enxuan Jing	C Ronald Kahn	Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.	NIDDK NIH HHS; R24DK085610
Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL	SIRT3 and cancer: tumor promoter or suppressor?	Biochim. Biophys. Acta	1816:1:80-8	2011	21586315		Turki Y Alhazzazi, Pachiyappan Kamarajan, Eric Verdin, Yvonne L Kapila	Turki Y Alhazzazi	Yvonne L Kapila	Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, MI 48109-1078, USA.	NIDCR NIH HHS; R56DE014429
Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E	Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes.	J. Immunol.	186:8:4782-93	2011	21398603		Herbert G Kasler, Bryan D Young, Denis Mottet, Hyung W Lim, Amy M Collins, Eric N Olson, Eric Verdin	Herbert G Kasler	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.	NIAID NIH HHS; 1R56 AI076664
Hakre S, Chavez L, Shirakawa K, Verdin E	Epigenetic regulation of HIV latency.	Curr Opin HIV AIDS	6:1:19-24	2011	21242889		Shweta Hakre, Leonard Chavez, Kotaro Shirakawa, Eric Verdin	Shweta Hakre	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California, USA.	NIDA NIH HHS; R01 DA030216
Tentchev D, Verdin E, Marchal C, Jacquet M, Aguilar JM, Moury B	Evolution and structure of Tomato spotted wilt virus populations: evidence of extensive reassortment and insights into emergence processes.	J. Gen. Virol.	92:Pt 4:961-73	2011	21169211		Diana Tentchev, Eric Verdin, Cécile Marchal, Monique Jacquet, Juan M Aguilar, Benoît Moury	Diana Tentchev	Benoît Moury	INRA, UR407 Pathologie Végétale, 84140 Montfavet, France.	NA
Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E	SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production.	Cell Metab.	12:6:654-61	2010	21109197		Tadahiro Shimazu, Matthew D Hirschey, Lan Hua, Kristin E Dittenhafer-Reed, Bjoern Schwer, David B Lombard, Yu Li, Jakob Bunkenborg, Frederick W Alt, John M Denu, Matthew P Jacobson, Eric Verdin	Tadahiro Shimazu	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	Howard Hughes Medical Institute; 
Qiu X, Brown K, Hirschey MD, Verdin E, Chen D	Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation.	Cell Metab.	12:6:662-7	2010	21109198		Xiaolei Qiu, Katharine Brown, Matthew D Hirschey, Eric Verdin, Danica Chen	Xiaolei Qiu	Danica Chen	Department of Nutritional Science & Toxicology, University of California, Berkeley, CA 94720, USA.	NA
Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL	Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer.	Cancer	117:8:1670-8	2011	21472714		Turki Y Alhazzazi, Pachiyappan Kamarajan, Nam Joo, Jing-Yi Huang, Eric Verdin, Nisha J D'Silva, Yvonne L Kapila	Turki Y Alhazzazi	Yvonne L Kapila	Department of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48109-1078, USA.	NIDCR NIH HHS; R56 DE014429-05A1
Verdin E, Hirschey MD, Finley LW, Haigis MC	Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling.	Trends Biochem. Sci.	35:12:669-75	2010	20863707		Eric Verdin, Matthew D Hirschey, Lydia W S Finley, Marcia C Haigis	Eric Verdin	Marcia C Haigis	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA. everdin@gladstone.ucsf.edu	NIA NIH HHS; R01 AG032375-03
Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, Leeuwenburgh C, McBurney M, Nabeshima Y, Neri C, Oberdoerffer P, Pestell RG, Rogina B, Sadoshima J, Sartorelli V, Serrano M, Sinclair DA, Steegborn C, Tatar M, Tissenbaum HA, Tong Q, Tsubota K, Vaquero A, Verdin E	Dietary restriction: standing up for sirtuins.	Science	329:5995:1012-3; author reply 1013-4	2010	20798296		Joseph A Baur, Danica Chen, Eduardo N Chini, Katrin Chua, Haim Y Cohen, Rafael de Cabo, Chuxia Deng, Stefanie Dimmeler, David Gius, Leonard P Guarente, Stephen L Helfand, Shin-Ichiro Imai, Hiroshi Itoh, Takashi Kadowaki, Daisuke Koya, Christiaan Leeuwenburgh, Michael McBurney, Yo-Ichi Nabeshima, Christian Neri, Philipp Oberdoerffer, Richard G Pestell, Blanka Rogina, Junichi Sadoshima, Vittorio Sartorelli, Manuel Serrano, David A Sinclair, Clemens Steegborn, Marc Tatar, Heidi A Tissenbaum, Qiang Tong, Kazuo Tsubota, Alejandro Vaquero, Eric Verdin	Joseph A Baur	Eric Verdin		NHLBI NIH HHS; R01 HL102738-02
Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N	HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals.	Science	329:5988:174-80	2010	20616270		Didier Trono, Carine Van Lint, Christine Rouzioux, Eric Verdin, Françoise Barré-Sinoussi, Tae-Wook Chun, Nicolas Chomont	Didier Trono	Nicolas Chomont	School of Life Sciences and Frontiers-in-Genetics Program, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland. Didier.trono@epfl.ch	NA
Chávez L, Kauder S, Verdin E	In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.	Methods	53:1:47-53	2011	20670606		Leonard Chávez, Steven Kauder, Eric Verdin	Leonard Chávez	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, 1650 Owens Street, CA 94158-2261, USA. leonard.chavez@ucsf.edu	NIGMS NIH HHS; R25-GM56847
Ott M, Verdin E	HAT trick: p300, small molecule, inhibitor.	Chem. Biol.	17:5:417-8	2010	20534339		Melanie Ott, Eric Verdin	Melanie Ott	Eric Verdin	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, 1650 Owens St., San Francisco, CA 94158, USA. mott@gladstone.ucsf.edu	NA
Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E	Acetate metabolism and aging: An emerging connection.	Mech. Ageing Dev.	131:7-8:511-6		20478325		Tadahiro Shimazu, Matthew D Hirschey, Jing-Yi Huang, Linh T Y Ho, Eric Verdin	Tadahiro Shimazu	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Parra M, Verdin E	Regulatory signal transduction pathways for class IIa histone deacetylases.	Curr Opin Pharmacol	10:4:454-60	2010	20447866		Maribel Parra, Eric Verdin	Maribel Parra	Eric Verdin	Cellular Differentiation Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Av. Gran Via s/n km 2.7, 08907 L'Hospitalet, Barcelona, Spain.	NA
Carle P, Saillard C, Carrère N, Carrère S, Duret S, Eveillard S, Gaurivaud P, Gourgues G, Gouzy J, Salar P, Verdin E, Breton M, Blanchard A, Laigret F, Bové JM, Renaudin J, Foissac X	Partial chromosome sequence of Spiroplasma citri reveals extensive viral invasion and important gene decay.	Appl. Environ. Microbiol.	76:11:3420-6	2010	20363791		Patricia Carle, Colette Saillard, Nathalie Carrère, Sébastien Carrère, Sybille Duret, Sandrine Eveillard, Patrice Gaurivaud, Géraldine Gourgues, Jérome Gouzy, Pascal Salar, Eric Verdin, Marc Breton, Alain Blanchard, Frédéric Laigret, Joseph-Marie Bové, Joel Renaudin, Xavier Foissac	Patricia Carle	Xavier Foissac	UMR1090 Génomique Diversité Pouvoir Pathogène, 71 Avenue Edouard Bourlaux, Villenave d'Ornon Cedex, France.	NA
Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, Hall MN, Hekimi S, Helfand SL, Karlseder J, Kenyon C, Kroemer G, Longo V, Nussenzweig A, Osiewacz HD, Peeper DS, Rando TA, Rudolph KL, Sassone-Corsi P, Serrano M, Sharpless NE, Skulachev VP, Tilly JL, Tower J, Verdin E, Vijg J	Impact papers on aging in 2009.	Aging (Albany NY)	2:3:111-21	2010	20351400		Mikhail V Blagosklonny, Judy Campisi, David A Sinclair, Andrzej Bartke, Maria A Blasco, William M Bonner, Vilhelm A Bohr, Robert M Brosh, Anne Brunet, Ronald A Depinho, Lawrence A Donehower, Caleb E Finch, Toren Finkel, Myriam Gorospe, Andrei V Gudkov, Michael N Hall, Siegfried Hekimi, Stephen L Helfand, Jan Karlseder, Cynthia Kenyon, Guido Kroemer, Valter Longo, Andre Nussenzweig, Heinz D Osiewacz, Daniel S Peeper, Thomas A Rando, K Lenhard Rudolph, Paolo Sassone-Corsi, Manuel Serrano, Norman E Sharpless, Vladimir P Skulachev, Jonathan L Tilly, John Tower, Eric Verdin, Jan Vijg	Mikhail V Blagosklonny	Jan Vijg	Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA. Blagosklonny@oncotarget.com	NCI NIH HHS; R01 CA084628-19
Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M	The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription.	Cell Host Microbe	7:3:234-44	2010	20227666		Sara Pagans, Steven E Kauder, Katrin Kaehlcke, Naoki Sakane, Sebastian Schroeder, Wilma Dormeyer, Raymond C Trievel, Eric Verdin, Martina Schnolzer, Melanie Ott	Sara Pagans	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01 AI083139-01A1
Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E	Mitochondrial sirtuins.	Biochim. Biophys. Acta	1804:8:1645-51	2010	20060508		Jing-Yi Huang, Matthew D Hirschey, Tadahiro Shimazu, Linh Ho, Eric Verdin	Jing-Yi Huang	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	NA
Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S	Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.	Mol. Cell. Biol.	30:2:399-412	2010	19917725		Simeen Malik, Shiming Jiang, Jason P Garee, Eric Verdin, Adrian V Lee, Bert W O'Malley, Mao Zhang, Narasimhaswamy S Belaguli, Steffi Oesterreich	Simeen Malik	Steffi Oesterreich	Department of Molecular and Cellular Biology, 3 Baylor College of Medicine, Houston, Texas 77030, USA.	NCI NIH HHS; R01 CA097213
Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I	CpG methylation controls reactivation of HIV from latency.	PLoS Pathog.	5:8:e1000554	2009	19696893		Jana Blazkova, Katerina Trejbalova, Françoise Gondois-Rey, Philippe Halfon, Patrick Philibert, Allan Guiguen, Eric Verdin, Daniel Olive, Carine Van Lint, Jiri Hejnar, Ivan Hirsch	Jana Blazkova	Ivan Hirsch	Institut National de la Santé et de la Recherche Médicale (INSERM), UMR891, Centre de Recherche en Cancérologie de Marseille; and Institut Paoli-Calmettes, Marseille, France.	NA
Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E	Epigenetic regulation of HIV-1 latency by cytosine methylation.	PLoS Pathog.	5:6:e1000495	2009	19557157		Steven E Kauder, Alberto Bosque, Annica Lindqvist, Vicente Planelles, Eric Verdin	Steven E Kauder	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America.	NIAID NIH HHS; AI49057
Cooper HM, Huang JY, Verdin E, Spelbrink JN	A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein.	PLoS ONE	4:3:e4986	2009	19333382		Helen M Cooper, Jing-Yi Huang, Eric Verdin, Johannes N Spelbrink	Helen M Cooper	Johannes N Spelbrink	University of Tampere, Institute of Medical Technology and Tampere University Hospital, Tampere, Finland.	NA
Saunders LR, Verdin E	Cell biology. Stress response and aging.	Science	323:5917:1021-2	2009	19229027		Laura R Saunders, Eric Verdin	Laura R Saunders	Eric Verdin	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S	The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.	J. Neurosci.	29:5:1525-37	2009	19193899		Sean A Pintchovski, Carol L Peebles, Hong Joo Kim, Eric Verdin, Steven Finkbeiner	Sean A Pintchovski	Steven Finkbeiner	Gladstone Institute of Neurological Disease, San Francisco, California 94158, USA.	NINDS NIH HHS; R01 NS039074-09
Schäfer S, Saunders L, Schlimme S, Valkov V, Wagner JM, Kratz F, Sippl W, Verdin E, Jung M	Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors.	ChemMedChem	4:2:283-90	2009	19090524		Stefan Schäfer, Laura Saunders, Sonja Schlimme, Vassil Valkov, Julia M Wagner, Felix Kratz, Wolfgang Sippl, Eric Verdin, Manfred Jung	Stefan Schäfer	Manfred Jung	Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Germany.	NA
Hirschey MD, Shimazu T, Huang JY, Verdin E	Acetylation of mitochondrial proteins.	Meth. Enzymol.	457:137-47	2009	19426866		Matthew D Hirschey, Tadahiro Shimazu, Jing-Yi Huang, Eric Verdin	Matthew D Hirschey	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California, USA.	NA
Uciechowska U, Schemies J, Neugebauer RC, Huda EM, Schmitt ML, Meier R, Verdin E, Jung M, Sippl W	Thiobarbiturates as sirtuin inhibitors: virtual screening, free-energy calculations, and biological testing.	ChemMedChem	3:12:1965-76	2008	18985648		Urszula Uciechowska, Jörg Schemies, Robert C Neugebauer, Elisabeth-Maria Huda, Martin L Schmitt, Rene Meier, Eric Verdin, Manfred Jung, Wolfgang Sippl	Urszula Uciechowska	Wolfgang Sippl	Martin-Luther Universität Halle-Wittenberg, Department of Pharmaceutical Chemistry, Wolfgang-Langenbeckstr. 4, 06120 Halle/Saale, Germany.	NA
Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V	HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.	Oncogene	28:2:243-56	2009	18850004		D Mottet, S Pirotte, V Lamour, M Hagedorn, S Javerzat, A Bikfalvi, A Bellahcène, E Verdin, V Castronovo	D Mottet	V Castronovo	Metastasis Research Laboratory, GIGA-Cancer (Center for Experimental Cancer Research), University of Liège, Liège, Belgium.	NA
Scott GK, Marx C, Berger CE, Saunders LR, Verdin E, Schäfer S, Jung M, Benz CC	Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6.	Mol. Cancer Res.	6:7:1250-8	2008	18644987		Gary K Scott, Corina Marx, Crystal E Berger, Laura R Saunders, Eric Verdin, Stefan Schäfer, Manfred Jung, Christopher C Benz	Gary K Scott	Christopher C Benz	Buck Institute for Age Research, Novato, CA 94945, USA. gscott@buckinstitute.org	NCI NIH HHS; R01-CA36773
Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN	Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7.	Proc. Natl. Acad. Sci. U.S.A.	105:22:7738-43	2008	18509061		Shusheng Wang, Xiumin Li, Maribel Parra, Eric Verdin, Rhonda Bassel-Duby, Eric N Olson	Shusheng Wang	Eric N Olson	Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9148.	NA
Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M	Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode.	J. Med. Chem.	51:5:1203-13	2008	18269226		Robert C Neugebauer, Urszula Uchiechowska, Rene Meier, Henning Hruby, Vassil Valkov, Eric Verdin, Wolfgang Sippl, Manfred Jung	Robert C Neugebauer	Manfred Jung	Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104 Freiburg, Germany.	NA
Schwer B, Verdin E	Conserved metabolic regulatory functions of sirtuins.	Cell Metab.	7:2:104-12	2008	18249170		Bjoern Schwer, Eric Verdin	Bjoern Schwer	Eric Verdin	Gladstone Institute of Virology and Immunology, San Francisco, CA 94158, USA.	NA
Verdin E	Regulation of human immunodeficiency virus-1 latency and its reactivation.	Bull. Mem. Acad. R. Med. Belg.	163:6:355-64; discussion 364-5	2008	19445107		E Verdin	E Verdin	E Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, USA.	NA
Verdin E	AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.	Mol. Cell	28:3:354-6	2007	17996699		Eric Verdin	Eric Verdin	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA. everdin@gladstone.ucsf.edu	NA
Schäfer S, Saunders L, Eliseeva E, Velena A, Jung M, Schwienhorst A, Strasser A, Dickmanns A, Ficner R, Schlimme S, Sippl W, Verdin E, Jung M	Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs).	Bioorg. Med. Chem.	16:4:2011-33	2008	18054239		Stefan Schäfer, Laura Saunders, Elena Eliseeva, Alfredo Velena, Mira Jung, Andreas Schwienhorst, Anja Strasser, Achim Dickmanns, Ralf Ficner, Sonja Schlimme, Wolfgang Sippl, Eric Verdin, Manfred Jung	Stefan Schäfer	Manfred Jung	Institute of Pharmaceutical Sciences, University of Freiburg, Albertstr. 25, 79104 Freiburg, Germany.	NA
North BJ, Verdin E	Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis.	PLoS ONE	2:8:e784	2007	17726514		Brian J North, Eric Verdin	Brian J North	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California at San Francisco, California, United States of America.	NA
Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E	Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.	J. Biol. Chem.	282:46:33583-92	2007	17715127		Nidhi Ahuja, Bjoern Schwer, Stefania Carobbio, David Waltregny, Brian J North, Vincenzo Castronovo, Pierre Maechler, Eric Verdin	Nidhi Ahuja	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NA
Saunders LR, Verdin E	Sirtuins: critical regulators at the crossroads between cancer and aging.	Oncogene	26:37:5489-504	2007	17694089		L R Saunders, E Verdin	L R Saunders	E Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	NA
Bisgrove DA, Mahmoudi T, Henklein P, Verdin E	Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.	Proc. Natl. Acad. Sci. U.S.A.	104:34:13690-5	2007	17690245		Dwayne A Bisgrove, Tokameh Mahmoudi, Peter Henklein, Eric Verdin	Dwayne A Bisgrove	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; P30 AI27763
Barrett A, Santangelo S, Tan K, Catchpole S, Roberts K, Spencer-Dene B, Hall D, Scibetta A, Burchell J, Verdin E, Freemont P, Taylor-Papadimitriou J	Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases.	Int. J. Cancer	121:2:265-75	2007	17373667		Angela Barrett, Samantha Santangelo, Keith Tan, Steve Catchpole, Kevin Roberts, Bradley Spencer-Dene, Debbie Hall, Angelo Scibetta, Joy Burchell, Eric Verdin, Paul Freemont, Joyce Taylor-Papadimitriou	Angela Barrett	Joyce Taylor-Papadimitriou	Cancer Research UK Breast Cancer Biology Group, King's College London School of Medicine, Guy's Hospital, London, United Kingdom.	NA
North BJ, Verdin E	Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation.	J. Biol. Chem.	282:27:19546-55	2007	17488717		Brian J North, Eric Verdin	Brian J North	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California San Francisco, California 94158, USA.	NA
Kasler HG, Verdin E	Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes.	Mol. Cell. Biol.	27:14:5184-200	2007	17470548		Herbert G Kasler, Eric Verdin	Herbert G Kasler	Eric Verdin	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Fanciulli M, Chenevix-Trench G, Young DB, Khanna KK	A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.	J. Biol. Chem.	282:20:15248-57	2007	17379597		Julia K Pagan, Jeremy Arnold, Kim J Hanchard, Raman Kumar, Tiziana Bruno, Mathew J K Jones, Derek J Richard, Alistair Forrest, Amanda Spurdle, Eric Verdin, Merlin Crossley, Maurizio Fanciulli, Georgia Chenevix-Trench, David B Young, Kum Kum Khanna	Julia K Pagan	Kum Kum Khanna	Queensland Institute of Medical Research, 300 Herston Road, Herston 4029, Queensland, Australia.	NA
Parra M, Mahmoudi T, Verdin E	Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.	Genes Dev.	21:6:638-43	2007	17369396		Maribel Parra, Tokameh Mahmoudi, Eric Verdin	Maribel Parra	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California 94158, USA.	NCRR NIH HHS; RR 18928-01
Krennhrubec K, Marshall BL, Hedglin M, Verdin E, Ulrich SM	Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors.	Bioorg. Med. Chem. Lett.	17:10:2874-8	2007	17346959		Keris Krennhrubec, Brett L Marshall, Mark Hedglin, Eric Verdin, Scott M Ulrich	Keris Krennhrubec	Scott M Ulrich	Department of Chemistry, Ithaca College, Ithaca, NY 14850, USA.	NA
Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dang NH, Hosoi H, Verdin E, Mizutani S	Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells.	Cancer Res.	67:3:1019-29	2007	17283134		Kumiko Ohnuma-Ishikawa, Tomohiro Morio, Takayuki Yamada, Yuji Sugawara, Makoto Ono, Masayuki Nagasawa, Akio Yasuda, Chikao Morimoto, Kei Ohnuma, Nam H Dang, Hajime Hosoi, Eric Verdin, Shuki Mizutani	Kumiko Ohnuma-Ishikawa	Shuki Mizutani	Department of Pediatrics, Graduate Medical School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 11308519, Japan.	NA
Trapp J, Jochum A, Meier R, Saunders L, Marshall B, Kunick C, Verdin E, Goekjian P, Sippl W, Jung M	Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition.	J. Med. Chem.	49:25:7307-16	2006	17149860		Johannes Trapp, Anne Jochum, Rene Meier, Laura Saunders, Brett Marshall, Conrad Kunick, Eric Verdin, Peter Goekjian, Wolfgang Sippl, Manfred Jung	Johannes Trapp	Manfred Jung	Institute of Pharmaceutical Sciences, Albert-Ludwigs-Universität Freiburg, Albertstrasse 25, 79104 Freiburg, Germany.	NA
Saunders LR, Verdin E	Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors.	Mol. Cancer Ther.	5:11:2777-85	2006	17121924		Laura R Saunders, Eric Verdin	Laura R Saunders	Eric Verdin	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA. everdin@gladstone.ucsf.edu	NA
Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E	Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2.	Proc. Natl. Acad. Sci. U.S.A.	103:27:10224-9	2006	16788062		Bjoern Schwer, Jakob Bunkenborg, Regis O Verdin, Jens S Andersen, Eric Verdin	Bjoern Schwer	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E	The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.	J. Biol. Chem.	281:29:19960-8	2006	16687403		Tokameh Mahmoudi, Maribel Parra, Robert G J Vries, Steven E Kauder, C Peter Verrijzer, Melanie Ott, Eric Verdin	Tokameh Mahmoudi	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NIGMS NIH HHS; R01 GM051671
Parrella G, Verdin E, Gognalons P, Marchoux G	Detection and characterization of tobacco mild green mosaic virus (TMGMV) large type isolate from trailing petunia in France.	Commun. Agric. Appl. Biol. Sci.	71:3 Pt B:1237-44	2006	17390885		G Parrella, E Verdin, P Gognalons, G Marchoux	G Parrella	G Marchoux	Istituto per la Protezione delle Piante del CNR, Via Università 133, 80055 Portici (NA), Italy. giuseppe.parrella@ipp.cnr.it	NA
Olaharski AJ, Rine J, Marshall BL, Babiarz J, Zhang L, Verdin E, Smith MT	The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases.	PLoS Genet.	1:6:e77	2005	16362078		Andrew J Olaharski, Jasper Rine, Brett L Marshall, Joshua Babiarz, Luoping Zhang, Eric Verdin, Martyn T Smith	Andrew J Olaharski	Martyn T Smith	School of Public Health, University of California Berkeley, Berkeley, California, USA. drewski@berkeley.edu	NIGMS NIH HHS; R01 GM31105
Bisgrove D, Lewinski M, Bushman F, Verdin E	Molecular mechanisms of HIV-1 proviral latency.	Expert Rev Anti Infect Ther	3:5:805-14	2005	16207172		Dwayne Bisgrove, Mary Lewinski, Frederic Bushman, Eric Verdin	Dwayne Bisgrove	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA. dbisgrove@gladstone.ucsf.edu	NA
North BJ, Schwer B, Ahuja N, Marshall B, Verdin E	Preparation of enzymatically active recombinant class III protein deacetylases.	Methods	36:4:338-45	2005	16091304		Brian J North, Bjoern Schwer, Nidhi Ahuja, Brett Marshall, Eric Verdin	Brian J North	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	NA
Wittich S, Scherf H, Xie C, Heltweg B, Dequiedt F, Verdin E, Gerhäuser C, Jung M	Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines.	Anticancer Drugs	16:6:635-43	2005	15930892		Sybille Wittich, Hans Scherf, Changping Xie, Birgit Heltweg, Franck Dequiedt, Eric Verdin, Clarissa Gerhäuser, Manfred Jung	Sybille Wittich	Manfred Jung	Department of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Germany.	NA
Lewinski MK, Bisgrove D, Shinn P, Chen H, Hoffmann C, Hannenhalli S, Verdin E, Berry CC, Ecker JR, Bushman FD	Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.	J. Virol.	79:11:6610-9	2005	15890899		M K Lewinski, D Bisgrove, P Shinn, H Chen, C Hoffmann, S Hannenhalli, E Verdin, C C Berry, J R Ecker, F D Bushman	M K Lewinski	F D Bushman	Infectious Disease Laboratory, The Salk Institute, La Jolla, California 92037, USA.	NIAID NIH HHS; AI52845
Jayakumar P, Berger I, Autschbach F, Weinstein M, Funke B, Verdin E, Goldsmith MA, Keppler OT	Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.	J. Virol.	79:8:5220-6	2005	15795306		Prerana Jayakumar, Irina Berger, Frank Autschbach, Mark Weinstein, Benjamin Funke, Eric Verdin, Mark A Goldsmith, Oliver T Keppler	Prerana Jayakumar	Oliver T Keppler	Gladstone Institute of Virology and Immunology, San Francisco General Hospital, University of California San Francisco, San Francisco, California, USA.	NCI NIH HHS; CA86814
Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V	Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility.	FASEB J.	19:8:966-8	2005	15772115		David Waltregny, Wendy Glénisson, Siv Ly Tran, Brian J North, Eric Verdin, Alain Colige, Vincent Castronovo	David Waltregny	Vincent Castronovo	Metastasis Research Laboratory, University of Liège, Liège, Belgium. david.waltregny@ulg.ac.be	NA
Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M	SIRT1 regulates HIV transcription via Tat deacetylation.	PLoS Biol.	3:2:e41	2005	15719057		Sara Pagans, Angelika Pedal, Brian J North, Katrin Kaehlcke, Brett L Marshall, Alexander Dorr, Claudia Hetzer-Egger, Peter Henklein, Roy Frye, Michael W McBurney, Henning Hruby, Manfred Jung, Eric Verdin, Melanie Ott	Sara Pagans	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, USA.	NA
Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E	Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation.	J. Biol. Chem.	280:14:13762-70	2005	15623513		Maribel Parra, Herbert Kasler, Timothy A McKinsey, Eric N Olson, Eric Verdin	Maribel Parra	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA.	NA
Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M	Subtype selective substrates for histone deacetylases.	J. Med. Chem.	47:21:5235-43	2004	15456267		Birgit Heltweg, Franck Dequiedt, Brett L Marshall, Carsten Brauch, Minoru Yoshida, Norikazu Nishino, Eric Verdin, Manfred Jung	Birgit Heltweg	Manfred Jung	Department of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Hittorfstrasse 58-62, 48149 Münster, Germany.	NA
Waltregny D, De Leval L, Glénisson W, Ly Tran S, North BJ, Bellahcène A, Weidle U, Verdin E, Castronovo V	Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues.	Am. J. Pathol.	165:2:553-64	2004	15277229		David Waltregny, Laurence De Leval, Wendy Glénisson, Siv Ly Tran, Brian J North, Akeila Bellahcène, Ulrich Weidle, Eric Verdin, Vincent Castronovo	David Waltregny	Vincent Castronovo	Metastasis Research Laboratory, Pathology Building, Bat. B23, level -1, CHU Sart Tilman Liège, B-4000 Liège 1, Belgium. david.waltregny@ulg.ac.be.	NA
Waltregny D, North B, Van Mellaert F, de Leval J, Verdin E, Castronovo V	Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells.	Eur J Histochem	48:3:273-90		15590418		D Waltregny, B North, F Van Mellaert, J de Leval, E Verdin, V Castronovo	D Waltregny	V Castronovo	Metastasis Research Laboratory, Pathology Building, Bat. B23, level -1, CHU Sart Tilman Liège, B-4000 Liège 1, Belgium. david.waltregny@ulg.ac.be	NA
North BJ, Verdin E	Sirtuins: Sir2-related NAD-dependent protein deacetylases.	Genome Biol.	5:5:224	2004	15128440		Brian J North, Eric Verdin	Brian J North	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94141, USA.	NA
Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E	Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation.	Novartis Found. Symp.	259:182-93; discussion 193-6, 223-5	2004	15171254		Melanie Ott, Alexander Dorr, Claudia Hetzer-Egger, Katrin Kaehlcke, Martina Schnolzer, Peter Henklein, Phil Cole, Ming-Ming Zhou, Eric Verdin	Melanie Ott	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, 365 Vermont Street, San Francisco, CA 94103, USA.	NA
Verdin E, Dequiedt F, Fischle W, Frye R, Marshall B, North B	Measurement of mammalian histone deacetylase activity.	Meth. Enzymol.	377:180-96	2004	14979025		Eric Verdin, Franck Dequiedt, Wolfgang Fischle, Roy Frye, Brett Marshall, Brian North	Eric Verdin	Brian North	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California 94103, USA.	NA
Verdin E, Dequiedt F, Kasler H	HDAC7 regulates apoptosis in developing thymocytes.	Novartis Found. Symp.	259:115-29; discussion 129-31, 163-9	2004	15171250		Eric Verdin, Frank Dequiedt, Herb Kasler	Eric Verdin	Herb Kasler	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, PO Box 419100, San Francisco, CA 94141-9100, USA.	NA
Heltweg B, Dequiedt F, Verdin E, Jung M	Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases.	Anal. Biochem.	319:1:42-8	2003	12842105		Birgit Heltweg, Franck Dequiedt, Eric Verdin, Manfred Jung	Birgit Heltweg	Manfred Jung	Department of Pharmaceutical and Medicinal Chemistry, Westfälische Wilhelms-Universität Münster, Hittorfstr. 58-62, Münster 48149, Germany.	NA
Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M	Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation.	Mol. Cell	12:1:167-76	2003	12887902		Katrin Kaehlcke, Alexander Dorr, Claudia Hetzer-Egger, Veronique Kiermer, Peter Henklein, Martina Schnoelzer, Erwann Loret, Philip A Cole, Eric Verdin, Melanie Ott	Katrin Kaehlcke	Melanie Ott	Deutsches Krebsforschungszentrum, D-69120 Heidelberg, Germany.	NIGMS NIH HHS; GM 62437
Danet JL, Foissac X, Zreik L, Salar P, Verdin E, Nourrisseau JG, Garnier M	"Candidatus Phlomobacter fragariae" Is the Prevalent Agent of Marginal Chlorosis of Strawberry in French Production Fields and Is Transmitted by the Planthopper Cixius wagneri (China).	Phytopathology	93:6:644-9	2003	18943049		Jean-Luc Danet, Xavier Foissac, Leyla Zreik, Pascal Salar, Eric Verdin, Jean-Georges Nourrisseau, Monique Garnier	Jean-Luc Danet	Monique Garnier		NA
Verdin E, Salar P, Danet JL, Choueiri E, Jreijiri F, El Zammar S, Gélie B, Bové JM, Garnier M	'Candidatus phytoplasma phoenicium' sp. nov., a novel phytoplasma associated with an emerging lethal disease of almond trees in Lebanon and Iran.	Int. J. Syst. Evol. Microbiol.	53:Pt 3:833-8	2003	12807209		Eric Verdin, Pascal Salar, Jean-Luc Danet, Elia Choueiri, Fouad Jreijiri, Souheir El Zammar, Brigitte Gélie, Joseph M Bové, Monique Garnier	Eric Verdin	Monique Garnier	UMR GDPP, Institut National de la Recherche Agronomique BP 81, 33883 Villenave d'Ornon, France.	NA
Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E	HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis.	Immunity	18:5:687-98	2003	12753745		Franck Dequiedt, Herbert Kasler, Wolfgang Fischle, Veronique Kiermer, Marc Weinstein, Brian G Herndier, Eric Verdin	Franck Dequiedt	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco 94141, USA.	NIGMS NIH HHS; GM51671
Verdin E, Dequiedt F, Kasler HG	Class II histone deacetylases: versatile regulators.	Trends Genet.	19:5:286-93	2003	12711221		Eric Verdin, Franck Dequiedt, Herbert G Kasler	Eric Verdin	Herbert G Kasler	Gladstone Institute of Virology and Immunology, University of California San Francisco, PO Box 419100, San Francisco, CA 94141, USA. everdin@gladstone.ucsf.edu	NA
Jordan A, Bisgrove D, Verdin E	HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.	EMBO J.	22:8:1868-77	2003	12682019		Albert Jordan, Dwayne Bisgrove, Eric Verdin	Albert Jordan	Eric Verdin	Department of Medicine, University of California, San Francisco, CA 94141, USA.	NIGMS NIH HHS; GM51671-05A2
Pion M, Jordan A, Biancotto A, Dequiedt F, Gondois-Rey F, Rondeau S, Vigne R, Hejnar J, Verdin E, Hirsch I	Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation.	J. Virol.	77:7:4025-32	2003	12634362		Marjorie Pion, Albert Jordan, Angelique Biancotto, Franck Dequiedt, Françoise Gondois-Rey, Sophie Rondeau, Robert Vigne, Jiri Hejnar, Eric Verdin, Ivan Hirsch	Marjorie Pion	Ivan Hirsch	INSERM U372, Unité de Pathogénie des Infections à Lentivirus, Parc Scientifique et Technologique de Luminy, 13276 Marseille, France.	NA
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E	The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase.	Mol. Cell	11:2:437-44	2003	12620231		Brian J North, Brett L Marshall, Margie T Borra, John M Denu, Eric Verdin	Brian J North	Eric Verdin	Department of Physiology, University of California, San Francisco, 94141, San Francisco, CA, USA	NA
Schwer B, North BJ, Frye RA, Ott M, Verdin E	The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.	J. Cell Biol.	158:4:647-57	2002	12186850		Bjorn Schwer, Brian J North, Roy A Frye, Melanie Ott, Eric Verdin	Bjorn Schwer	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California San Francisco, 365 Vermont Street, San Francisco, CA 94103, USA.	NA
Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M	Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain.	EMBO J.	21:11:2715-23	2002	12032084		Alexander Dorr, Veronique Kiermer, Angelika Pedal, Hans-Richard Rackwitz, Peter Henklein, Ulrich Schubert, Ming-Ming Zhou, Eric Verdin, Melanie Ott	Alexander Dorr	Melanie Ott	Deutsches Krebsforschungszentrum (DKFZ), 69120 Heidelberg, D-10115 Berlin, Germany,	NIAID NIH HHS; AI 40847
Murphy JC, Fischle W, Verdin E, Sinclair JH	Control of cytomegalovirus lytic gene expression by histone acetylation.	EMBO J.	21:5:1112-20	2002	11867539		Jane C Murphy, Wolfgang Fischle, Eric Verdin, John H Sinclair	Jane C Murphy	John H Sinclair	Department of Medicine, University of Cambridge, Cambridge CB2 2QQ, UK. jcm25@mole.bio.cam.ac.uk	NA
Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou MM	Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain.	Mol. Cell	9:3:575-86	2002	11931765		Shiraz Mujtaba, Yan He, Lei Zeng, Amjad Farooq, Justin E Carlson, Melanie Ott, Eric Verdin, Ming-Ming Zhou	Shiraz Mujtaba	Ming-Ming Zhou	Structural Biology Program, Department of Physiology and Biophysics, Mount Sinai School of Medicine, New York University, New York, NY 10029, USA.	NA
Borra MT, O'Neill FJ, Jackson MD, Marshall B, Verdin E, Foltz KR, Denu JM	Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases.	J. Biol. Chem.	277:15:12632-41	2002	11812793		Margie T Borra, Forest J O'Neill, Michael D Jackson, Brett Marshall, Eric Verdin, Kathy R Foltz, John M Denu	Margie T Borra	John M Denu	Department of Biochemistry and Molecular Biology, Oregon Health and Sciences University, Portland, OR 97201-3098, USA.	NA
Deroanne CF, Bonjean K, Servotte S, Devy L, Colige A, Clausse N, Blacher S, Verdin E, Foidart JM, Nusgens BV, Castronovo V	Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling.	Oncogene	21:3:427-36	2002	11821955		Christophe F Deroanne, Karine Bonjean, Sandrine Servotte, Laetitia Devy, Alain Colige, Nathalie Clausse, Sylvia Blacher, Eric Verdin, Jean-Michel Foidart, Betty V Nusgens, Vincent Castronovo	Christophe F Deroanne	Vincent Castronovo	Research Center in Experimental Cancerology, University of Liège, Sart-Tilman, B-4000 Liège, Belgium. LCTB@ulg.ac.be	NA
Fischle W, Dequiedt F, Hendzel MJ, Guenther MG, Lazar MA, Voelter W, Verdin E	Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR.	Mol. Cell	9:1:45-57	2002	11804585		Wolfgang Fischle, Franck Dequiedt, Michael J Hendzel, Matthew G Guenther, Mitchell A Lazar, Wolfgang Voelter, Eric Verdin	Wolfgang Fischle	Eric Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA 94141, USA.	NIGMS NIH HHS; GM51671
Kruhlak MJ, Hendzel MJ, Fischle W, Bertos NR, Hameed S, Yang XJ, Verdin E, Bazett-Jones DP	Regulation of global acetylation in mitosis through loss of histone acetyltransferases and deacetylases from chromatin.	J. Biol. Chem.	276:41:38307-19	2001	11479283		M J Kruhlak, M J Hendzel, W Fischle, N R Bertos, S Hameed, X J Yang, E Verdin, D P Bazett-Jones	M J Kruhlak	D P Bazett-Jones	Research Institute, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, Canada.	NA
Fischle W, Dequiedt F, Fillion M, Hendzel MJ, Voelter W, Verdin E	Human HDAC7 histone deacetylase activity is associated with HDAC3 in vivo.	J. Biol. Chem.	276:38:35826-35	2001	11466315		W Fischle, F Dequiedt, M Fillion, M J Hendzel, W Voelter, E Verdin	W Fischle	E Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141-9100, USA.	NIGMS NIH HHS; GM51671
Jordan A, Defechereux P, Verdin E	The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation.	EMBO J.	20:7:1726-38	2001	11285236		A Jordan, P Defechereux, E Verdin	A Jordan	E Verdin	Gladstone Institute of Virology and Immunology and Department of Medicine, University of California, San Francisco, CA 94141, USA.	NIGMS NIH HHS; GM 51671-05A2
Geenen V, Verdin E	[Egg-cell complex, molecular embryology, human genome, then, human proteome].	Rev Med Liege	56:3:170	2001	11338789		V Geenen, E Verdin	V Geenen	E Verdin		NA
Fischle W, Kiermer V, Dequiedt F, Verdin E	The emerging role of class II histone deacetylases.	Biochem. Cell Biol.	79:3:337-48	2001	11467747		W Fischle, V Kiermer, F Dequiedt, E Verdin	W Fischle	E Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco 94141-9100, USA.	NA
Verdin E, Kobisch M, Bové JM, Garnier M, Saillard C	Use of an internal control in a nested-PCR assay for Mycoplasma hyopneumoniae detection and quantification in tracheobronchiolar washings from pigs.	Mol. Cell. Probes	14:6:365-72	2000	11090266		E Verdin, M Kobisch, J M Bové, M Garnier, C Saillard	E Verdin	C Saillard	UMR GDPP, Laboratoire de Biologie Cellulaire et Moléculaire, IBVM, Centre INRA de Bordeaux, 33883 Villenave dOrnon, France.	NA
Verdin E, Saillard C, Labbé A, Bové JM, Kobisch M	A nested PCR assay for the detection of Mycoplasma hyopneumoniae in tracheobronchiolar washings from pigs.	Vet. Microbiol.	76:1:31-40	2000	10925039		E Verdin, C Saillard, A Labbé, J M Bové, M Kobisch	E Verdin	M Kobisch	INRA - Domaine de la Grande Ferrade, Laboratoire de Biologie Cellulaire et Moléculaire, P.O. Box 81, 33883 Villenave d'Ornon Cedex, France.	NA
Gaurivaud P, Laigret F, Verdin E, Garnier M, Bové JM	Fructose operon mutants of Spiroplasma citri.	Microbiology (Reading, Engl.)	146 ( Pt 9):2229-36	2000	10974110		P Gaurivaud, F Laigret, E Verdin, M Garnier, J M Bové	P Gaurivaud	J M Bové	Laboratoire de Biologie Cellulaire et Moléculaire, Institut de Biologie Végétale Moléculaire, Institut National de la Recherche Agronomique and Université Victor Segalen Bordeaux 2, France.	NA
Huynh KD, Fischle W, Verdin E, Bardwell VJ	BCoR, a novel corepressor involved in BCL-6 repression.	Genes Dev.	14:14:1810-23	2000	10898795		K D Huynh, W Fischle, E Verdin, V J Bardwell	K D Huynh	V J Bardwell	Biochemistry, Molecular Biology, and Biophysics Program, University of Minnesota, Minneapolis, Minnesota 55455, USA.	NCI NIH HHS; 5R29CA71540
Kruhlak MJ, Lever MA, Fischle W, Verdin E, Bazett-Jones DP, Hendzel MJ	Reduced mobility of the alternate splicing factor (ASF) through the nucleoplasm and steady state speckle compartments.	J. Cell Biol.	150:1:41-51	2000	10893255		M J Kruhlak, M A Lever, W Fischle, E Verdin, D P Bazett-Jones, M J Hendzel	M J Kruhlak	M J Hendzel	Department of Anatomy, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.	NA
Guenther MG, Lane WS, Fischle W, Verdin E, Lazar MA, Shiekhattar R	A core SMRT corepressor complex containing HDAC3 and TBL1, a WD40-repeat protein linked to deafness.	Genes Dev.	14:9:1048-57	2000	10809664		M G Guenther, W S Lane, W Fischle, E Verdin, M A Lazar, R Shiekhattar	M G Guenther	R Shiekhattar	Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine and Genetics, and The Penn Diabetes Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 USA.	NA
Wang JK, Kiyokawa E, Verdin E, Trono D	The Nef protein of HIV-1 associates with rafts and primes T cells for activation.	Proc. Natl. Acad. Sci. U.S.A.	97:1:394-9	2000	10618429		J K Wang, E Kiyokawa, E Verdin, D Trono	J K Wang	D Trono	Department of Genetics and Microbiology, University of Geneva, CH-1211 Geneva, Switzerland.	NIAID NIH HHS; R37 AI 34306
Ott M, Schnölzer M, Garnica J, Fischle W, Emiliani S, Rackwitz HR, Verdin E	Acetylation of the HIV-1 Tat protein by p300 is important for its transcriptional activity.	Curr. Biol.	9:24:1489-92		10607594		M Ott, M Schnölzer, J Garnica, W Fischle, S Emiliani, H R Rackwitz, E Verdin	M Ott	E Verdin	Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, 69120, Germany.	NA
Mahlknecht U, Hoelzer D, Bucala R, Verdin E	Cloning and characterization of the murine histone deacetylase (HDAC3).	Biochem. Biophys. Res. Commun.	263:2:482-90	1999	10491319		U Mahlknecht, D Hoelzer, R Bucala, E Verdin	U Mahlknecht	E Verdin	Picower Institute for Medical Research, 350 Community Drive, Manhasset, New York, 11030, USA. Mahlknecht@em.uni-frankfurt.de	NA
Critchfield JW, Ho O, Roberts BD, Van Lint C, Verdin E, Butera ST	Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency.	Antivir. Chem. Chemother.	10:5:275-84	1999	10574182		J W Critchfield, O Ho, B D Roberts, C Van Lint, E Verdin, S T Butera	J W Critchfield	S T Butera	HIV and Retrovirology Branch, Division of AIDS, STD and TB Laboratory Research, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.	NA
Fischle W, Emiliani S, Hendzel MJ, Nagase T, Nomura N, Voelter W, Verdin E	A new family of human histone deacetylases related to Saccharomyces cerevisiae HDA1p.	J. Biol. Chem.	274:17:11713-20	1999	10206986		W Fischle, S Emiliani, M J Hendzel, T Nagase, N Nomura, W Voelter, E Verdin	W Fischle	E Verdin	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141-9100, USA.	PHS HHS; R016M516
Mahlknecht U, Emiliani S, Najfeld V, Young S, Verdin E	Genomic organization and chromosomal localization of the human histone deacetylase 3 gene.	Genomics	56:2:197-202	1999	10051405		U Mahlknecht, S Emiliani, V Najfeld, S Young, E Verdin	U Mahlknecht	E Verdin	The Picower Institute for Medical Research, 350 Community Drive, Manhasset, New York 11030, USA.	NA
Mahlknecht U, Bucala R, Verdin E	Assignment of the histone deacetylase gene (Hdac3) to mouse chromosome 18B3 by in situ hybridization.	Cytogenet. Cell Genet.	84:3-4:192-3	1999	10393429		U Mahlknecht, R Bucala, E Verdin	U Mahlknecht	E Verdin	The Picower Institute for Medical Research, Manhasset, NY, USA. Mahlknecht@em.uni-frankfurt.de	NA
Mahlknecht U, Bucala R, Hoelzer D, Verdin E	High resolution physical mapping of human HDAC3, a potential tumor suppressor gene in the 5q31 region.	Cytogenet. Cell Genet.	86:3-4:237-9	1999	10575214		U Mahlknecht, R Bucala, D Hoelzer, E Verdin	U Mahlknecht	E Verdin	Laboratory of Medical Biochemistry, The Picower Institute for Medical Research, Manhasset NY, USA. Mahlknecht@em.uni-frankfurt.de	NA
Herbein G, Mahlknecht U, Batliwalla F, Gregersen P, Pappas T, Butler J, O'Brien WA, Verdin E	Apoptosis of CD8+ T cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4.	Nature	395:6698:189-94	1998	9744279		G Herbein, U Mahlknecht, F Batliwalla, P Gregersen, T Pappas, J Butler, W A O'Brien, E Verdin	G Herbein	E Verdin	The Picower Institute for Medical Research, Manhasset, New York 11010, USA.	NA
Kiermer V, Van Lint C, Briclet D, Vanhulle C, Kettmann R, Verdin E, Burny A, Droogmans L	An interferon regulatory factor binding site in the U5 region of the bovine leukemia virus long terminal repeat stimulates Tax-independent gene expression.	J. Virol.	72:7:5526-34	1998	9621009		V Kiermer, C Van Lint, D Briclet, C Vanhulle, R Kettmann, E Verdin, A Burny, L Droogmans	V Kiermer	L Droogmans	Department of Molecular Biology, University of Brussels, B1640 Rhode-Saint-Genèse, Belgium. vkiermer@dbm.ulb.ac.be	NA
Emiliani S, Fischle W, Van Lint C, Al-Abed Y, Verdin E	Characterization of a human RPD3 ortholog, HDAC3.	Proc. Natl. Acad. Sci. U.S.A.	95:6:2795-800	1998	9501169		S Emiliani, W Fischle, C Van Lint, Y Al-Abed, E Verdin	S Emiliani	E Verdin	Picower Institute for Medical Research, Manhasset, NY 11030, USA.	NIGMS NIH HHS; GM51671
Richon VM, Emiliani S, Verdin E, Webb Y, Breslow R, Rifkind RA, Marks PA	A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.	Proc. Natl. Acad. Sci. U.S.A.	95:6:3003-7	1998	9501205		V M Richon, S Emiliani, E Verdin, Y Webb, R Breslow, R A Rifkind, P A Marks	V M Richon	P A Marks	Cell Biology Program, Memorial Sloan-Kettering Cancer Center 1275 York Avenue, New York, NY 10021, USA. v-richon@ski.mskcc.org	NCI NIH HHS; CA-0874823
Ott M, Lovett JL, Mueller L, Verdin E	Superinduction of IL-8 in T cells by HIV-1 Tat protein is mediated through NF-kappaB factors.	J. Immunol.	160:6:2872-80	1998	9510190		M Ott, J L Lovett, L Mueller, E Verdin	M Ott	E Verdin	The Picower Institute for Medical Research, Manhasset, NY 11030, USA.	NIAID NIH HHS; R01 AI 40847-01A1
Emiliani S, Fischle W, Ott M, Van Lint C, Amella CA, Verdin E	Mutations in the tat gene are responsible for human immunodeficiency virus type 1 postintegration latency in the U1 cell line.	J. Virol.	72:2:1666-70	1998	9445075		S Emiliani, W Fischle, M Ott, C Van Lint, C A Amella, E Verdin	S Emiliani	E Verdin	The Picower Institute for Medical Research, Manhasset, New York 11030, USA.	NIAID NIH HHS; R01 AI 40847-01A1
Herbein G, Van Lint C, Lovett JL, Verdin E	Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes.	J. Virol.	72:1:660-70	1998	9420271		G Herbein, C Van Lint, J L Lovett, E Verdin	G Herbein	E Verdin	The Picower Institute for Medical Research, Manhasset, New York 11030, USA.	NIAID NIH HHS; AI40847-01A1
Sheridan PL, Mayall TP, Verdin E, Jones KA	Histone acetyltransferases regulate HIV-1 enhancer activity in vitro.	Genes Dev.	11:24:3327-40	1997	9407026		P L Sheridan, T P Mayall, E Verdin, K A Jones	P L Sheridan	K A Jones	The Salk Institute for Biological Studies, La Jolla, California 92037-1099, USA.	NIGMS NIH HHS; GM 38166
Van Lint C, Amella CA, Emiliani S, John M, Jie T, Verdin E	Transcription factor binding sites downstream of the human immunodeficiency virus type 1 transcription start site are important for virus infectivity.	J. Virol.	71:8:6113-27	1997	9223506		C Van Lint, C A Amella, S Emiliani, M John, T Jie, E Verdin	C Van Lint	E Verdin	The Picower Institute for Medical Research, Manhasset, New York 11030, USA.	NIGMS NIH HHS; GM51671-02
Ott M, Emiliani S, Van Lint C, Herbein G, Lovett J, Chirmule N, McCloskey T, Pahwa S, Verdin E	Immune hyperactivation of HIV-1-infected T cells mediated by Tat and the CD28 pathway.	Science	275:5305:1481-5	1997	9045614		M Ott, S Emiliani, C Van Lint, G Herbein, J Lovett, N Chirmule, T McCloskey, S Pahwa, E Verdin	M Ott	E Verdin	The Picower Institute for Medical Research, 350 Community Drive, Manhasset, NY 11030, USA.	NA
McCloskey TW, Ott M, Tribble E, Khan SA, Teichberg S, Paul MO, Pahwa S, Verdin E, Chirmule N	Dual role of HIV Tat in regulation of apoptosis in T cells.	J. Immunol.	158:2:1014-9	1997	8993024		T W McCloskey, M Ott, E Tribble, S A Khan, S Teichberg, M O Paul, S Pahwa, E Verdin, N Chirmule	T W McCloskey	N Chirmule	Department of Pediatrics, North Shore University Hospital-Cornell University Medical College, Manhasset, NY 11030, USA.	NIDA NIH HHS; DA0561
Emiliani S, Van Lint C, Fischle W, Paras P, Ott M, Brady J, Verdin E	A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency.	Proc. Natl. Acad. Sci. U.S.A.	93:13:6377-81	1996	8692823		S Emiliani, C Van Lint, W Fischle, P Paras, M Ott, J Brady, E Verdin	S Emiliani	E Verdin	The Picower Institute for Medical Research, Manhasset, NY 11030, USA.	NIGMS NIH HHS; GM51671-01A1
Van Lint C, Emiliani S, Ott M, Verdin E	Transcriptional activation and chromatin remodeling of the HIV-1 promoter in response to histone acetylation.	EMBO J.	15:5:1112-20	1996	8605881		C Van Lint, S Emiliani, M Ott, E Verdin	C Van Lint	E Verdin	The Picower Institute for Medical Research, Manhasset, NY 11030, USA.	NIGMS NIH HHS; GM51671-01A1
Van Lint C, Emiliani S, Verdin E	The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.	Gene Expr.	5:4-5:245-53	1996	8723390		C Van Lint, S Emiliani, E Verdin	C Van Lint	E Verdin	Laboratory of Molecular Virology, Picower Institute for Medical Research, Manhasset, NY 11030, USA.	NIGMS NIH HHS; GM51671-01A1
Renaudin J, Marais A, Verdin E, Duret S, Foissac X, Laigret F, Bové JM	Integrative and free Spiroplasma citri oriC plasmids: expression of the Spiroplasma phoeniceum spiralin in Spiroplasma citri.	J. Bacteriol.	177:10:2870-7	1995	7751299		J Renaudin, A Marais, E Verdin, S Duret, X Foissac, F Laigret, J M Bové	J Renaudin	J M Bové	Laboratoire de Biologie Cellulaire et Moléculaire, Institut National de la Recherche Agronomique, Villenave d'Ornon, France.	NA
Verdin E, Van Lint C	Internal transcriptional regulatory elements in HIV-1 and other retroviruses.	Cell. Mol. Biol. (Noisy-le-grand)	41:3:365-9	1995	7580829		E Verdin, C Van Lint	E Verdin	C Van Lint	Picower Institute for Medical Research, Laboratory of Molecular Virology, Manhasset, NY 11030, USA.	NA
el Kharroubi A, Verdin E	Protein-DNA interactions within DNase I-hypersensitive sites located downstream of the HIV-1 promoter.	J. Biol. Chem.	269:31:19916-24	1994	8051074		A el Kharroubi, E Verdin	A el Kharroubi	E Verdin	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892.	NA
Van Lint C, Ghysdael J, Paras P, Burny A, Verdin E	A transcriptional regulatory element is associated with a nuclease-hypersensitive site in the pol gene of human immunodeficiency virus type 1.	J. Virol.	68:4:2632-48	1994	8139041		C Van Lint, J Ghysdael, P Paras, A Burny, E Verdin	C Van Lint	E Verdin	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892.	NA
Verdin E, Paras P, Van Lint C	Chromatin disruption in the promoter of human immunodeficiency virus type 1 during transcriptional activation.	EMBO J.	12:8:3249-59	1993	8344262		E Verdin, P Paras, C Van Lint	E Verdin	C Van Lint	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD 20892.	NA
Sharpless N, Gilbert D, Vandercam B, Zhou JM, Verdin E, Ronnett G, Friedman E, Dubois-Dalcq M	The restricted nature of HIV-1 tropism for cultured neural cells.	Virology	191:2:813-25	1992	1448925		N Sharpless, D Gilbert, B Vandercam, J M Zhou, E Verdin, G Ronnett, E Friedman, M Dubois-Dalcq	N Sharpless	M Dubois-Dalcq	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892.	NA
Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen IS, Dubois-Dalcq M	Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism.	J. Virol.	66:4:2588-93	1992	1548785		N E Sharpless, W A O'Brien, E Verdin, C V Kufta, I S Chen, M Dubois-Dalcq	N E Sharpless	M Dubois-Dalcq	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892.	NA
Van Lint C, Burny A, Verdin E	The intragenic enhancer of human immunodeficiency virus type 1 contains functional AP-1 binding sites.	J. Virol.	65:12:7066-72	1991	1942259		C Van Lint, A Burny, E Verdin	C Van Lint	E Verdin	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892.	NA
Verdin E	DNase I-hypersensitive sites are associated with both long terminal repeats and with the intragenic enhancer of integrated human immunodeficiency virus type 1.	J. Virol.	65:12:6790-9	1991	1942252		E Verdin	E Verdin	E Verdin	Laboratory of Viral and Molecular Pathogenesis, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892.	NA
Montgomery LB, Kao CY, Verdin E, Cahill C, Maratos-Flier E	Infection of a polarized epithelial cell line with wild-type reovirus leads to virus persistence and altered cellular function.	J. Gen. Virol.	72 ( Pt 12):2939-46	1991	1765767		L B Montgomery, C Y Kao, E Verdin, C Cahill, E Maratos-Flier	L B Montgomery	E Maratos-Flier	Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215.	NA
Verdin E, Deveaux E, Deveaux B	[Forced eruption, a clinical procedure: apropos of 2 clinical cases].	Inf Dent	72:31:2711-20	1990	2228178		E Verdin, E Deveaux, B Deveaux	E Verdin	B Deveaux	U.F.R. d'Odontologie, Université de Lille II 59045.	NA
Verdin E, Becker N, Bex F, Droogmans L, Burny A	Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.	Proc. Natl. Acad. Sci. U.S.A.	87:12:4874-8	1990	2352955		E Verdin, N Becker, F Bex, L Droogmans, A Burny	E Verdin	A Burny	Université Libre de Bruxelles, Département de Biologie Moléculaire, Rhode-St-Genèse, Belgium.	NA
Delchambre M, Gheysen D, Thines D, Thiriart C, Jacobs E, Verdin E, Horth M, Burny A, Bex F	The GAG precursor of simian immunodeficiency virus assembles into virus-like particles.	EMBO J.	8:9:2653-60	1989	2684654		M Delchambre, D Gheysen, D Thines, C Thiriart, E Jacobs, E Verdin, M Horth, A Burny, F Bex	M Delchambre	F Bex	Department of Molecular Biology, University of Brussels, Belgium.	NA
Verdin EM, King GL, Maratos-Flier E	Characterization of a common high-affinity receptor for reovirus serotypes 1 and 3 on endothelial cells.	J. Virol.	63:3:1318-25	1989	2915382		E M Verdin, G L King, E Maratos-Flier	E M Verdin	E Maratos-Flier	Research Division, Joslin Diabetes Center, Boston, Massachusetts.	NEI NIH HHS; EY-0511001
Verdin EM, Lynn SP, Fields BN, Maratos-Flier E	Uptake of reovirus serotype 1 by the lungs from the bloodstream is mediated by the viral hemagglutinin.	J. Virol.	62:2:545-51	1988	3336070		E M Verdin, S P Lynn, B N Fields, E Maratos-Flier	E M Verdin	E Maratos-Flier	Elliot P. Joslin Research Laboratory, Joslin Diabetes Center, Boston, Massachusetts.	NIADDK NIH HHS; AM01252
Burny A, Bex F, Brasseur R, Khim MC, Delchambre M, Horth M, Verdin E	Human immunodeficiency virus cell entry: new insights into the fusion mechanism.	J. Acquir. Immune Defic. Syndr.	1:6:579-82	1988	2852244		A Burny, F Bex, R Brasseur, M C Khim, M Delchambre, M Horth, E Verdin	A Burny	E Verdin	Department of Molecular Biology, Free University of Brussels, Rhode Saint Genese, Belgium.	NA
Maratos-Flier E, Kao CY, Verdin EM, King GL	Receptor-mediated vectorial transcytosis of epidermal growth factor by Madin-Darby canine kidney cells.	J. Cell Biol.	105:4:1595-601	1987	3312235		E Maratos-Flier, C Y Kao, E M Verdin, G L King	E Maratos-Flier	G L King	Elliott P. Joslin Research Laboratory, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215.	NIDDK NIH HHS; DK 36433
Verdin EM, Maratos-Flier E, Kahn CR, Sodoyez JC, Sodoyez-Goffaux F, De Vos CJ, Lynn SP, Fields BN	Visualization of viral clearance in the living animal.	Science	236:4800:439-42	1987	3031817		E M Verdin, E Maratos-Flier, C R Kahn, J C Sodoyez, F Sodoyez-Goffaux, C J De Vos, S P Lynn, B N Fields	E M Verdin	B N Fields		NIADDK NIH HHS; AM 01252
Verdin EM, Maratos-Flier E, Carpentier JL, Kahn CR	Persistent infection with a nontransforming RNA virus leads to impaired growth factor receptors and response.	J. Cell. Physiol.	128:3:457-65	1986	3018005		E M Verdin, E Maratos-Flier, J L Carpentier, C R Kahn	E M Verdin	C R Kahn		NA
Paolisso G, Scheen AJ, Verdin EM, Luyckx AS, Lefebvre PJ	Insulin oscillations per se do not affect glucose turnover parameters in normal man.	J. Clin. Endocrinol. Metab.	63:2:520-5	1986	3522623		G Paolisso, A J Scheen, E M Verdin, A S Luyckx, P J Lefebvre	G Paolisso	P J Lefebvre		NA
Verdin E, Smitz S, Thibaut A, Born J, Legros JJ, Luyckx A	Adipsic hypernatremia in a patient with pseudotumor cerebri and the primary empty sella syndrome.	J. Endocrinol. Invest.	8:4:369-72	1985	4067208		E Verdin, S Smitz, A Thibaut, J Born, J J Legros, A Luyckx	E Verdin	A Luyckx		NA
Verdin E, Castillo M, Luyckx AS, Lefebvre PJ	Similar metabolic effects of pulsatile versus continuous human insulin delivery during euglycemic, hyperinsulinemic glucose clamp in normal man.	Diabetes	33:12:1169-74	1984	6389233		E Verdin, M Castillo, A S Luyckx, P J Lefebvre	E Verdin	P J Lefebvre		NA
Verdin EM, Green FW	VIP and the pancreatic cholera syndrome.	N. Engl. J. Med.	310:22:1465-6	1984	6325912		E M Verdin, F W Green	E M Verdin	F W Green		NA
Castillo M, Nemery A, Verdin E, Lefebvre PJ, Luyckx AS	Circadian profiles of blood glucose and plasma free insulin during treatment with semisynthetic and biosynthetic human insulin, and comparison with conventional monocomponent preparations.	Eur. J. Clin. Pharmacol.	25:6:767-71	1983	6363099		M Castillo, A Nemery, E Verdin, P J Lefebvre, A S Luyckx	M Castillo	A S Luyckx		NA
Baeten JM, Grant R	Use of Antiretrovirals for HIV Prevention: What Do We Know and What Don't We Know?	Curr HIV/AIDS Rep	10:2:142-51	2013	23494772		Jared M Baeten, Robert Grant	Jared M Baeten	Robert Grant	Departments of Global Health, Medicine, and Epidemiology, University of Washington, Box 359927, 325 Ninth Avenue, Seattle, WA, 98104, USA, jbaeten@uw.edu.	NIAID NIH HHS; U01 AI064002
Vallabhaneni S, McConnell JJ, Loeb L, Hartogensis W, Hecht FM, Grant RM, Pilcher CD	Changes in seroadaptive practices from before to after diagnosis of recent HIV infection among men who have sex with men.	PLoS ONE	8:2:e55397	2013	23405145		Snigdha Vallabhaneni, J Jeff McConnell, Lisa Loeb, Wendy Hartogensis, Fredrick M Hecht, Robert M Grant, Christopher D Pilcher	Snigdha Vallabhaneni	Christopher D Pilcher	Center for AIDS Prevention Studies, University of California San Francisco, San Francisco, CA, USA. snigdhav@gmail.com	PHS HHS; 5 P01 A1071713
Gomez GB, Borquez A, Caceres CF, Segura ER, Grant RM, Garnett GP, Hallett TB	The potential impact of pre-exposure prophylaxis for HIV prevention among men who have sex with men and transwomen in Lima, Peru: a mathematical modelling study.	PLoS Med.	9:10:e1001323	2012	23055836		Gabriela B Gomez, Annick Borquez, Carlos F Caceres, Eddy R Segura, Robert M Grant, Geoff P Garnett, Timothy B Hallett	Gabriela B Gomez	Timothy B Hallett	Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, United Kingdom.	Wellcome Trust; 
Anderson PL, Glidden DV, Liu A, Buchbinder S, Lama JR, Guanira JV, McMahan V, Bushman LR, Casapía M, Montoya-Herrera O, Veloso VG, Mayer KH, Chariyalertsak S, Schechter M, Bekker LG, Kallás EG, Grant RM	Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men.	Sci Transl Med	4:151:151ra125	2012	22972843		Peter L Anderson, David V Glidden, Albert Liu, Susan Buchbinder, Javier R Lama, Juan Vicente Guanira, Vanessa McMahan, Lane R Bushman, Martín Casapía, Orlando Montoya-Herrera, Valdilea G Veloso, Kenneth H Mayer, Suwat Chariyalertsak, Mauro Schechter, Linda-Gail Bekker, Esper Georges Kallás, Robert M Grant	Peter L Anderson	Robert M Grant	University of Colorado Denver, Aurora, CO 80045, USA.	NCRR NIH HHS; UL1 RR024131
Van Damme L, Corneli A, Ahmed K, Agot K, Lombaard J, Kapiga S, Malahleha M, Owino F, Manongi R, Onyango J, Temu L, Monedi MC, Mak'Oketch P, Makanda M, Reblin I, Makatu SE, Saylor L, Kiernan H, Kirkendale S, Wong C, Grant R, Kashuba A, Nanda K, Mandala J, Fransen K, Deese J, Crucitti T, Mastro TD, Taylor D	Preexposure prophylaxis for HIV infection among African women.	N. Engl. J. Med.	367:5:411-22	2012	22784040		Lut Van Damme, Amy Corneli, Khatija Ahmed, Kawango Agot, Johan Lombaard, Saidi Kapiga, Mookho Malahleha, Fredrick Owino, Rachel Manongi, Jacob Onyango, Lucky Temu, Modie Constance Monedi, Paul Mak'Oketch, Mankalimeng Makanda, Ilse Reblin, Shumani Elsie Makatu, Lisa Saylor, Haddie Kiernan, Stella Kirkendale, Christina Wong, Robert Grant, Angela Kashuba, Kavita Nanda, Justin Mandala, Katrien Fransen, Jennifer Deese, Tania Crucitti, Timothy D Mastro, Douglas Taylor	Lut Van Damme	Douglas Taylor	FHI 360, Research Triangle Park, North Carolina, USA. lvandamme@fhi360.org	NIAID NIH HHS; U01 AI095031
R Amico K, McMahan V, Goicochea P, Vargas L, Marcus JL, Grant RM, Liu A	Supporting study product use and accuracy in self-report in the iPrEx study: next step counseling and neutral assessment.	AIDS Behav	16:5:1243-59	2012	22460228		K R Amico, Vanessa McMahan, Pedro Goicochea, Lorena Vargas, Julia L Marcus, Robert M Grant, Albert Liu	K R Amico	Albert Liu	Center for Health Intervention and Prevention, University of Connecticut, Storrs, CT, USA. rivetamico@comcast.net	NIAID NIH HHS; UO1 AI064002
Truong HM, Kellogg TA, McFarland W, Louie B, Klausner JD, Philip SS, Grant RM	Sentinel surveillance of HIV-1 transmitted drug resistance, acute infection and recent infection.	PLoS ONE	6:10:e25281	2011	22046237		Hong-Ha M Truong, Timothy A Kellogg, Willi McFarland, Brian Louie, Jeffrey D Klausner, Susan S Philip, Robert M Grant	Hong-Ha M Truong	Robert M Grant	Department of Medicine, University of California San Francisco, San Francisco, California, United States of America. Hong-Ha.Truong@ucsf.edu	NA
Liu AY, Vittinghoff E, Sellmeyer DE, Irvin R, Mulligan K, Mayer K, Thompson M, Grant R, Pathak S, O'Hara B, Gvetadze R, Chillag K, Grohskopf L, Buchbinder SP	Bone mineral density in HIV-negative men participating in a tenofovir pre-exposure prophylaxis randomized clinical trial in San Francisco.	PLoS ONE	6:8:e23688	2011	21897852		Albert Y Liu, Eric Vittinghoff, Deborah E Sellmeyer, Risha Irvin, Kathleen Mulligan, Kenneth Mayer, Melanie Thompson, Robert Grant, Sonal Pathak, Brandon O'Hara, Roman Gvetadze, Kata Chillag, Lisa Grohskopf, Susan P Buchbinder	Albert Y Liu	Susan P Buchbinder	San Francisco Department of Public Health, San Francisco, California, United States of America. albert.liu@sfdph.org	NCRR NIH HHS; UL1 RR024131
Jain V, Sucupira MC, Bacchetti P, Hartogensis W, Diaz RS, Kallas EG, Janini LM, Liegler T, Pilcher CD, Grant RM, Cortes R, Deeks SG, Hecht FM	Differential persistence of transmitted HIV-1 drug resistance mutation classes.	J. Infect. Dis.	203:8:1174-81	2011	21451005		Vivek Jain, Maria C Sucupira, Peter Bacchetti, Wendy Hartogensis, Ricardo S Diaz, Esper G Kallas, Luiz M Janini, Teri Liegler, Christopher D Pilcher, Robert M Grant, Rodrigo Cortes, Steven G Deeks, Frederick M Hecht	Vivek Jain	Frederick M Hecht	HIV/AIDS Division, San Francisco General Hospital, University of California, San Francisco, San Francisco, CA 94143, USA.	NCRR NIH HHS; UL1 RR024131
Jain V, Liegler T, Vittinghoff E, Hartogensis W, Bacchetti P, Poole L, Loeb L, Pilcher CD, Grant RM, Deeks SG, Hecht FM	Transmitted drug resistance in persons with acute/early HIV-1 in San Francisco, 2002-2009.	PLoS ONE	5:12:e15510	2010	21170322		Vivek Jain, Teri Liegler, Eric Vittinghoff, Wendy Hartogensis, Peter Bacchetti, Lauren Poole, Lisa Loeb, Christopher D Pilcher, Robert M Grant, Steven G Deeks, Frederick M Hecht	Vivek Jain	Frederick M Hecht	HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America.	NCRR NIH HHS; UL1 RR024131
Anderson PL, Kiser JJ, Gardner EM, Rower JE, Meditz A, Grant RM	Pharmacological considerations for tenofovir and emtricitabine to prevent HIV infection.	J. Antimicrob. Chemother.	66:2:240-50	2011	21118913		Peter L Anderson, Jennifer J Kiser, Edward M Gardner, Joseph E Rower, Amie Meditz, Robert M Grant	Peter L Anderson	Robert M Grant	Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, CO, USA. peter.anderson@ucdenver.edu	NIAID NIH HHS; AI084735
Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, Goicochea P, Casapía M, Guanira-Carranza JV, Ramirez-Cardich ME, Montoya-Herrera O, Fernández T, Veloso VG, Buchbinder SP, Chariyalertsak S, Schechter M, Bekker LG, Mayer KH, Kallás EG, Amico KR, Mulligan K, Bushman LR, Hance RJ, Ganoza C, Defechereux P, Postle B, Wang F, McConnell JJ, Zheng JH, Lee J, Rooney JF, Jaffe HS, Martinez AI, Burns DN, Glidden DV	Preexposure chemoprophylaxis for HIV prevention in men who have sex with men.	N. Engl. J. Med.	363:27:2587-99	2010	21091279		Robert M Grant, Javier R Lama, Peter L Anderson, Vanessa McMahan, Albert Y Liu, Lorena Vargas, Pedro Goicochea, Martín Casapía, Juan Vicente Guanira-Carranza, Maria E Ramirez-Cardich, Orlando Montoya-Herrera, Telmo Fernández, Valdilea G Veloso, Susan P Buchbinder, Suwat Chariyalertsak, Mauro Schechter, Linda-Gail Bekker, Kenneth H Mayer, Esper Georges Kallás, K Rivet Amico, Kathleen Mulligan, Lane R Bushman, Robert J Hance, Carmela Ganoza, Patricia Defechereux, Brian Postle, Furong Wang, J Jeff McConnell, Jia-Hua Zheng, Jeanny Lee, James F Rooney, Howard S Jaffe, Ana I Martinez, David N Burns, David V Glidden	Robert M Grant	David V Glidden	J. David Gladstone Institutes, University of California at San Francisco, 1650 Owens St., San Francisco, CA 94158, USA. robert.grant@ucsf.edu	NCRR NIH HHS; UL1 RR024131-04S3
Burrell E, Mark D, Grant R, Wood R, Bekker LG	Sexual risk behaviours and HIV-1 prevalence among urban men who have sex with men in Cape Town, South Africa.	Sex Health	7:2:149-53	2010	20465978		Earl Burrell, Daniella Mark, Robert Grant, Robin Wood, Linda-Gail Bekker	Earl Burrell	Linda-Gail Bekker	Desmond Tutu HIV Centre, University of Cape Town, Cape Town 7705, South Africa. earl.burrell@ucla.edu	NA
Grant RM	Antiretroviral agents used by HIV-uninfected persons for prevention: pre- and postexposure prophylaxis.	Clin. Infect. Dis.	50 Suppl 3:S96-101	2010	20397962		Robert M Grant	Robert M Grant	Robert M Grant	Gladstone Institute of Virology and Immunology and University of California, San Francisco, USA. robert.grant@ucsf.edu	NA
Hecht FM, Hartogensis W, Bragg L, Bacchetti P, Atchison R, Grant R, Barbour J, Deeks SG	HIV RNA level in early infection is predicted by viral load in the transmission source.	AIDS	24:7:941-5	2010	20168202		Frederick M Hecht, Wendy Hartogensis, Larry Bragg, Peter Bacchetti, Robert Atchison, Robert Grant, Jason Barbour, Steven G Deeks	Frederick M Hecht	Steven G Deeks	HIV/AIDS Division, Department of Medicine, San Francisco General Hospital, University of California, CA 94110, USA. rhecht@php.ucsf.edu	PHS HHS; R18/CCR 920936
McConnell JJ, Bragg L, Shiboski S, Grant RM	Sexual seroadaptation: lessons for prevention and sex research from a cohort of HIV-positive men who have sex with men.	PLoS ONE	5:1:e8831	2010	20098616		J Jeff McConnell, Larry Bragg, Stephen Shiboski, Robert M Grant	J Jeff McConnell	Robert M Grant	Gladstone Institute of Virology and Immunology, San Francisco, California, United States of America. jmcconnell@gladstone.ucsf.edu	PHS HHS; U64/CCU917889-01
Cardenas VA, Meyerhoff DJ, Studholme C, Kornak J, Rothlind J, Lampiris H, Neuhaus J, Grant RM, Chao LL, Truran D, Weiner MW	Evidence for ongoing brain injury in human immunodeficiency virus-positive patients treated with antiretroviral therapy.	J. Neurovirol.	15:4:324-33	2009	19499454		V A Cardenas, D J Meyerhoff, C Studholme, J Kornak, J Rothlind, H Lampiris, J Neuhaus, R M Grant, L L Chao, D Truran, M W Weiner	V A Cardenas	M W Weiner	University of California, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA. valerie.cardenas-nicolson@ucsf.edu	NIBIB NIH HHS; R03 EB008136-01
Truong HM, Kellogg T, Schwarcz S, Delgado V, Grant RM, Louie B, Ngo H, McFarland W	Frequent international travel by men who have sex with men recently diagnosed with HIV-1: potential for transmission of primary HIV-1 drug resistance.	J Travel Med	15:6:454-6		19090802		Hong M Truong, Timothy Kellogg, Sandra Schwarcz, Viva Delgado, Robert M Grant, Brian Louie, Houston Ngo, Willi McFarland	Hong M Truong	Willi McFarland	Center for AIDS Prevention Studies, University of California, San Francisco, 50 Beale Street, Suite 1300, San Francisco, CA 94105, USA. Hong-Ha.Truong@ucsf.edu	NA
Willberg CB, McConnell JJ, Eriksson EM, Bragg LA, York VA, Liegler TJ, Hecht FM, Grant RM, Nixon DF	Immunity to HIV-1 is influenced by continued natural exposure to exogenous virus.	PLoS Pathog.	4:10:e1000185	2008	18949024		Christian B Willberg, J Jeff McConnell, Emily M Eriksson, Larry A Bragg, Vanessa A York, Teri J Liegler, Fredrick M Hecht, Robert M Grant, Douglas F Nixon	Christian B Willberg	Douglas F Nixon	Division of Experimental Medicine, Department of Medicine, University of California San Francisco, San Francisco, California, USA. Chris.Willberg@ndm.ox.ac.uk	PHS HHS; U64/CCU917889-01
Erickson AL, Willberg CB, McMahan V, Liu A, Buchbinder SP, Grohskopf LA, Grant RM, Nixon DF	Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(+) T-cell responses which can be defined to the epitope level.	Clin. Vaccine Immunol.	15:11:1745-8	2008	18815234		A L Erickson, C B Willberg, V McMahan, A Liu, S P Buchbinder, L A Grohskopf, R M Grant, D F Nixon	A L Erickson	D F Nixon	Division of Experimental Medicine, Department of Medicine, UCSF, San Francisco, CA 94110, USA.	PHS HHS; U64/CCU917889-01
Grant RM, Hamer D, Hope T, Johnston R, Lange J, Lederman MM, Lieberman J, Miller CJ, Moore JP, Mosier DE, Richman DD, Schooley RT, Springer MS, Veazey RS, Wainberg MA	Whither or wither microbicides?	Science	321:5888:532-4	2008	18653884		Robert M Grant, Dean Hamer, Thomas Hope, Rowena Johnston, Joep Lange, Michael M Lederman, Judy Lieberman, Christopher J Miller, John P Moore, Donald E Mosier, Douglas D Richman, Robert T Schooley, Marty S Springer, Ronald S Veazey, Mark A Wainberg	Robert M Grant	Mark A Wainberg	J. David Gladstone Institutes, University of California-San Francisco, San Francisco, CA 94518, USA.	NIAID NIH HHS; U19 AI076981-01
Bourara K, Liegler TJ, Grant RM	Target cell APOBEC3C can induce limited G-to-A mutation in HIV-1.	PLoS Pathog.	3:10:1477-85	2007	17967058		Khaoula Bourara, Teri J Liegler, Robert M Grant	Khaoula Bourara	Robert M Grant	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California, USA.	NIAID NIH HHS; P30 AI27763-12
Grant RM	Research in situ.	Nat. Methods	4:11:887-90	2007	17952085		Robert M Grant	Robert M Grant	Robert M Grant	J. David Gladstone Institutes and University of California San Francisco, San Francisco, California 94158, USA. robert.grant@ucsf.edu	NA
Peterson L, Taylor D, Roddy R, Belai G, Phillips P, Nanda K, Grant R, Clarke EE, Doh AS, Ridzon R, Jaffe HS, Cates W	Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial.	PLoS Clin Trials	2:5:e27	2007	17525796		Leigh Peterson, Doug Taylor, Ronald Roddy, Ghiorghis Belai, Pamela Phillips, Kavita Nanda, Robert Grant, Edith Essie Kekawo Clarke, Anderson Sama Doh, Renee Ridzon, Howard S Jaffe, Willard Cates	Leigh Peterson	Willard Cates	Family Health International, Durham, North Carolina, United States of America. lpeterson@fhi.org	NA
Colfax GN, Vittinghoff E, Grant R, Lum P, Spotts G, Hecht FM	Frequent methamphetamine use is associated with primary non-nucleoside reverse transcriptase inhibitor resistance.	AIDS	21:2:239-41	2007	17197817		Grant Nash Colfax, Eric Vittinghoff, Robert Grant, Paula Lum, Gerald Spotts, Frederick M Hecht	Grant Nash Colfax	Frederick M Hecht	AIDS Office, San Francisco Department of Public Health, San Francisco, California, USA.	NIDA NIH HHS; 3R01DA017476-03F1
Abrams DI, Shade SB, Couey P, McCune JM, Lo J, Bacchetti P, Chang B, Epling L, Liegler T, Grant RM	Dehydroepiandrosterone (DHEA) effects on HIV replication and host immunity: a randomized placebo-controlled study.	AIDS Res. Hum. Retroviruses	23:1:77-85	2007	17263636		Donald I Abrams, Starley B Shade, Paul Couey, Joseph M McCune, Joan Lo, Peter Bacchetti, Barbara Chang, Lorrie Epling, Teri Liegler, Robert M Grant	Donald I Abrams	Robert M Grant	Community Consortium, Positive Health Program, University of California, San Francisco, CA 94143, USA. dabrams@php.ucsf.edu	NCRR NIH HHS; 5-M01-RR00083
Truong HM, Truong HH, Kellogg T, Klausner JD, Katz MH, Dilley J, Knapper K, Chen S, Prabhu R, Grant RM, Louie B, McFarland W	Increases in sexually transmitted infections and sexual risk behaviour without a concurrent increase in HIV incidence among men who have sex with men in San Francisco: a suggestion of HIV serosorting?	Sex Transm Infect	82:6:461-6	2006	17151031		H M Truong, H-H M Truong, T Kellogg, J D Klausner, M H Katz, J Dilley, K Knapper, S Chen, R Prabhu, R M Grant, B Louie, W McFarland	H M Truong	W McFarland	University of California at San Francisco, San Francisco, CA, USA.	NA
Truong HM, Grant RM, McFarland W, Kellogg T, Kent C, Louie B, Wong E, Klausner JD	Routine surveillance for the detection of acute and recent HIV infections and transmission of antiretroviral resistance.	AIDS	20:17:2193-7	2006	17086059		Hong-Ha M Truong, Robert M Grant, Willi McFarland, Timothy Kellogg, Charlotte Kent, Brian Louie, Ernest Wong, Jeffrey D Klausner	Hong-Ha M Truong	Jeffrey D Klausner	University of California-San Francisco, 50 Beale Street, San Francisco, CA 94105, USA. Hong-Ha.Truong@ucsf.edu	NA
Barbour JD, Hecht FM, Little SJ, Markowitz M, Daar ES, Kelleher AD, Routy JP, Campbell TB, Rosenberg ES, Segal MR, Weidler J, Grant RM	Greater CD4 T-cell gains after one year of antiretroviral therapy are associated with lower HIV-1 pol replication capacity.	AIDS	20:16:2123-5	2006	17053362		Jason D Barbour, Frederick M Hecht, Susan J Little, Martin Markowitz, Eric S Daar, Anthony D Kelleher, Jean-Pierre Routy, Thomas B Campbell, Eric S Rosenberg, Mark R Segal, Jodi Weidler, Robert M Grant	Jason D Barbour	Robert M Grant	Positive Health Program, Department of Medicine, San Francisco General Hospital, University of California, San Francisco, California, USA.	NCRR NIH HHS; M01-RR00425
Grant RM, Wainberg MA	Chemoprophylaxis of HIV infection: moving forward with caution.	J. Infect. Dis.	194:7:874-6	2006	16960773		Robert M Grant, Mark A Wainberg	Robert M Grant	Mark A Wainberg		NIAID NIH HHS; U01-AI064002
Levy V, Grant RM	Antiretroviral therapy for hepatitis B virus-HIV-coinfected patients: promises and pitfalls.	Clin. Infect. Dis.	43:7:904-10	2006	16941375		Vivian Levy, Robert M Grant	Vivian Levy	Robert M Grant	Stanford University Division of Infectious Diseases, USA. vlevy@stanford.edu	NA
Liu AY, Grant RM, Buchbinder SP	Preexposure prophylaxis for HIV: unproven promise and potential pitfalls.	JAMA	296:7:863-5	2006	16905792		Albert Y Liu, Robert M Grant, Susan P Buchbinder	Albert Y Liu	Susan P Buchbinder	HIV Research Section, San Francisco Department of Public Health, San Francisco, Calif 94102, USA. albert.liu@sfdph.org	NIAID NIH HHS; UO1 AI064002
Lama JR, Sanchez J, Suarez L, Caballero P, Laguna A, Sanchez JL, Whittington WL, Celum C, Grant RM	Linking HIV and antiretroviral drug resistance surveillance in Peru: a model for a third-generation HIV sentinel surveillance.	J. Acquir. Immune Defic. Syndr.	42:4:501-5	2006	16773026		Javier R Lama, Jorge Sanchez, Luis Suarez, Patricia Caballero, Alberto Laguna, Jose L Sanchez, William L H Whittington, Connie Celum, Robert M Grant	Javier R Lama	Robert M Grant	Asociacion Civil Impacta Salud y Educacion, Lima, Peru. jrlama@impactaperu.org	NIAID NIH HHS; UO1-AI064002
Sánchez MS, Grant RM, Porco TC, Getz WM	HIV drug-resistant strains as epidemiologic sentinels.	Emerging Infect. Dis.	12:2:191-7	2006	16494741		María S Sánchez, Robert M Grant, Travis C Porco, Wayne M Getz	María S Sánchez	Wayne M Getz	University of California, Berkeley, California 94720, USA. msanchez@nature.berkeley.edu	PHS HHS; R01-D10135
Gange SJ, Schneider MF, Grant RM, Liegler T, French A, Young M, Anastos K, Wilson TE, Ponath C, Greenblatt R	Genotypic resistance and immunologic outcomes among HIV-1-infected women with viral failure.	J. Acquir. Immune Defic. Syndr.	41:1:68-74	2006	16340476		Stephen J Gange, Michael F Schneider, Robert M Grant, Teri Liegler, Audrey French, Mary Young, Kathryn Anastos, Tracey E Wilson, Claudia Ponath, Ruth Greenblatt	Stephen J Gange	Ruth Greenblatt	Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA. sgange@jhsph.edu	NICHD NIH HHS; U01-HD-32632
Papasavvas E, Kostman JR, Thiel B, Pistilli M, Mackiewicz A, Foulkes A, Gross R, Jordan KA, Nixon DF, Grant R, Poulin JF, McCune JM, Mounzer K, Montaner LJ	HIV-1-specific CD4+ T cell responses in chronically HIV-1 infected blippers on antiretroviral therapy in relation to viral replication following treatment interruption.	J. Clin. Immunol.	26:1:40-54	2006	16418802		Emmanouil Papasavvas, Jay R Kostman, Brian Thiel, Maxwell Pistilli, Agnieszka Mackiewicz, Andrea Foulkes, Robert Gross, Kimberly A Jordan, Douglas F Nixon, Robert Grant, Jean-Francois Poulin, Joseph M McCune, Karam Mounzer, Luis J Montaner	Emmanouil Papasavvas	Luis J Montaner	The Wistar Institute, Philadelphia, Pennsylvania 19104, USA. montaner@wistar.org	NIAID NIH HHS; P30 AI060352
Chin-Hong PV, Deeks SG, Liegler T, Hagos E, Krone MR, Grant RM, Martin JN	High-risk sexual behavior in adults with genotypically proven antiretroviral-resistant HIV infection.	J. Acquir. Immune Defic. Syndr.	40:4:463-71	2005	16280703		Peter V Chin-Hong, Steven G Deeks, Teri Liegler, Elilta Hagos, Melissa R Krone, Robert M Grant, Jeffrey N Martin	Peter V Chin-Hong	Jeffrey N Martin	Department of Medicine, University of California at San Francisco and San Francisco General Hospital, San Francisco, CA, USA. pvch@itsa.ucsf.edu	NIAID NIH HHS; R01 AI052745
Roland ME, Neilands TB, Krone MR, Katz MH, Franses K, Grant RM, Busch MP, Hecht FM, Shacklett BL, Kahn JO, Bamberger JD, Coates TJ, Chesney MA, Martin JN	Seroconversion following nonoccupational postexposure prophylaxis against HIV.	Clin. Infect. Dis.	41:10:1507-13	2005	16231265		Michelle E Roland, Torsten B Neilands, Melissa R Krone, Mitchell H Katz, Karena Franses, Robert M Grant, Michael P Busch, Frederick M Hecht, Barbara L Shacklett, James O Kahn, Joshua D Bamberger, Thomas J Coates, Margaret A Chesney, Jeffrey N Martin	Michelle E Roland	Jeffrey N Martin	Positive Health Program at San Francisco General Hospital, California, USA. mroland@php.ucsf.edu	NIMH NIH HHS; R01 MH61180
Grant RM, Buchbinder S, Cates W, Clarke E, Coates T, Cohen MS, Delaney M, Flores G, Goicochea P, Gonsalves G, Harrington M, Lama JR, MacQueen KM, Moore JP, Peterson L, Sanchez J, Thompson M, Wainberg MA	AIDS. Promote HIV chemoprophylaxis research, don't prevent it.	Science	309:5744:2170-1	2005	16195446		Robert M Grant, Susan Buchbinder, Willard Cates, Edith Clarke, Thomas Coates, Myron S Cohen, Martin Delaney, Guiselly Flores, Pedro Goicochea, Gregg Gonsalves, Mark Harrington, Javier R Lama, Kathleen M MacQueen, John P Moore, Leigh Peterson, Jorge Sanchez, Melanie Thompson, Mark A Wainberg	Robert M Grant	Mark A Wainberg	Gladstone Institute of Virology and Immunology, San Francisco, CA, USA. rgrant@itsa.ucsf.edu	NA
Hecht FM, Grant RM	Resistance testing in drug-naive HIV-infected patients: is it time?	Clin. Infect. Dis.	41:9:1324-5	2005	16206109		Frederick M Hecht, Robert M Grant	Frederick M Hecht	Robert M Grant		NA
Deeks SG, Hoh R, Neilands TB, Liegler T, Aweeka F, Petropoulos CJ, Grant RM, Martin JN	Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection.	J. Infect. Dis.	192:9:1537-44	2005	16206068		Steven G Deeks, Rebecca Hoh, Torsten B Neilands, Teri Liegler, Francesca Aweeka, Christos J Petropoulos, Robert M Grant, Jeffrey N Martin	Steven G Deeks	Jeffrey N Martin	University of California, San Francisco, and San Francisco General Hospital, San Francisco 94110, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH62246
Neuenburg JK, Furlan S, Bacchetti P, Price RW, Grant RM	Enrichment of activated monocytes in cerebrospinal fluid during antiretroviral therapy.	AIDS	19:13:1351-9	2005	16103765		Jutta K Neuenburg, Scott Furlan, Peter Bacchetti, Richard W Price, Robert M Grant	Jutta K Neuenburg	Robert M Grant	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158, USA. jneuenburg@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS37660
Klausner JD, Grant RM, Kent CK	Detection of acute HIV infections.	N. Engl. J. Med.	353:6:631-3; author reply 631-3	2005	16093476		Jeffrey D Klausner, Robert M Grant, Charlotte K Kent	Jeffrey D Klausner	Charlotte K Kent		NA
Neuenburg JK, Cho TA, Nilsson A, Bredt BM, Hebert SJ, Grant RM, Price RW	T-cell activation and memory phenotypes in cerebrospinal fluid during HIV infection.	J. Acquir. Immune Defic. Syndr.	39:1:16-22	2005	15851909		Jutta K Neuenburg, Tracey A Cho, Annelie Nilsson, Barry M Bredt, Samuel J Hebert, Robert M Grant, Richard W Price	Jutta K Neuenburg	Richard W Price	Department of Neurology, San Francisco General Hospital, General Clinical Research Center at the University of California, San Francisco, CA 94158, USA. juttan@itsa.ucsf.edu	NCRR NIH HHS; RR-00083
Barbour JD, Grant RM	The role of viral fitness in HIV pathogenesis.	Curr HIV/AIDS Rep	2:1:29-34	2005	16091246		Jason D Barbour, Robert M Grant	Jason D Barbour	Robert M Grant	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NA
Papasavvas E, Kostman JR, Mounzer K, Grant RM, Gross R, Gallo C, Azzoni L, Foulkes A, Thiel B, Pistilli M, Mackiewicz A, Shull J, Montaner LJ	Randomized, controlled trial of therapy interruption in chronic HIV-1 infection.	PLoS Med.	1:3:e64	2004	15630469		Emmanouil Papasavvas, Jay R Kostman, Karam Mounzer, Robert M Grant, Robert Gross, Cele Gallo, Livio Azzoni, Andrea Foulkes, Brian Thiel, Maxwell Pistilli, Agnieszka Mackiewicz, Jane Shull, Luis J Montaner	Emmanouil Papasavvas	Luis J Montaner	The Wistar Institute, Philadelphia, Pennsylvania, USA.	NIAID NIH HHS; AI48398
Sánchez MS, Grant RM, Porco TC, Gross KL, Getz WM	A decrease in drug resistance levels of the HIV epidemic can be bad news.	Bull. Math. Biol.	67:4:761-82	2005	15893552		María S Sánchez, Robert M Grant, Travis C Porco, Kimber L Gross, Wayne M Getz	María S Sánchez	Wayne M Getz	Department of Environmental Science, Policy and Management, University of California, Berkeley, CA 94720, USA. msanchez@nature.berkeley.edu	PHS HHS; R01-D10135
Neuenburg JK, Sinclair E, Nilsson A, Kreis C, Bacchetti P, Price RW, Grant RM	HIV-producing T cells in cerebrospinal fluid.	J. Acquir. Immune Defic. Syndr.	37:2:1237-44	2004	15385730		Jutta K Neuenburg, Elizabeth Sinclair, Annelie Nilsson, Christophe Kreis, Peter Bacchetti, Richard W Price, Robert M Grant	Jutta K Neuenburg	Robert M Grant	Gladstone Institute of Virology and Immunology, San Francisco, CA, USA.	NCRR NIH HHS; RR-00083
Barbour JD, Hecht FM, Wrin T, Liegler TJ, Ramstead CA, Busch MP, Segal MR, Petropoulos CJ, Grant RM	Persistence of primary drug resistance among recently HIV-1 infected adults.	AIDS	18:12:1683-9	2004	15280779		Jason D Barbour, Frederick M Hecht, Terri Wrin, Teri J Liegler, Clarissa A Ramstead, Michael P Busch, Mark R Segal, Christos J Petropoulos, Robert M Grant	Jason D Barbour	Robert M Grant	Gladstone Institute of Virology and Immunology, San Francisco, California 94141-9100, USA.	ODCDC CDC HHS; R18/CCR 920936
Gross KL, Porco TC, Grant RM	HIV-1 superinfection and viral diversity.	AIDS	18:11:1513-20	2004	15238769		Kimber L Gross, Travis C Porco, Robert M Grant	Kimber L Gross	Robert M Grant	San Francisco Department of Public Health, San Francisco, California, USA.	ODCDC CDC HHS; U64/CCU 917889
Reyes-Sandoval A, Fitzgerald JC, Grant R, Roy S, Xiang ZQ, Li Y, Gao GP, Wilson JM, Ertl HC	Human immunodeficiency virus type 1-specific immune responses in primates upon sequential immunization with adenoviral vaccine carriers of human and simian serotypes.	J. Virol.	78:14:7392-9	2004	15220412		A Reyes-Sandoval, J C Fitzgerald, R Grant, S Roy, Z Q Xiang, Y Li, G P Gao, J M Wilson, H C J Ertl	A Reyes-Sandoval	H C J Ertl	Wistar Institute, Philadelphia, PA 19104, USA.	NA
Barbour JD, Hecht FM, Wrin T, Segal MR, Ramstead CA, Liegler TJ, Busch MP, Petropoulos CJ, Hellmann NS, Kahn JO, Grant RM	Higher CD4+ T cell counts associated with low viral pol replication capacity among treatment-naive adults in early HIV-1 infection.	J. Infect. Dis.	190:2:251-6	2004	15216458		Jason D Barbour, Frederick M Hecht, Terri Wrin, Mark R Segal, Clarissa A Ramstead, Teri J Liegler, Michael P Busch, Christos J Petropoulos, Nicholas S Hellmann, James O Kahn, Robert M Grant	Jason D Barbour	Robert M Grant	Gladstone Institute of Virology and Immunology, University of California, San Francisco, USA.	ODCDC CDC HHS; U64/CCU913941
Segal MR, Barbour JD, Grant RM	Relating HIV-1 sequence variation to replication capacity via trees and forests.	Stat Appl Genet Mol Biol	3:Article2; discussion article 7, article 9	2004	16646798		Mark R Segal, Jason D Barbour, Robert M Grant	Mark R Segal	Robert M Grant	University of California, San Francisco, USA. mark@biostat.ucsf.edu	NA
Angel JB, Hu YW, Kravcik S, Tsui R, Lee KH, Barbour J, Balaskas E, Branson BM, Delwart EL, Grant RM	Virological evaluation of the 'Ottawa case' indicates no evidence for HIV-1 superinfection.	AIDS	18:2:331-4	2004	15075555		Jonathan B Angel, Yu-Wen Hu, Stephen Kravcik, Rose Tsui, Kok H Lee, Jason Barbour, Evan Balaskas, Bernard M Branson, Eric L Delwart, Robert M Grant	Jonathan B Angel	Robert M Grant	Ottawa Health Research Institute and the Ottawa Hospital, University of Ottawa, Ottawa, Canada.	ODCDC CDC HHS; U64/CCU917889-01
Porco TC, Martin JN, Page-Shafer KA, Cheng A, Charlebois E, Grant RM, Osmond DH	Decline in HIV infectivity following the introduction of highly active antiretroviral therapy.	AIDS	18:1:81-8	2004	15090833		Travis C Porco, Jeffrey N Martin, Kimberly A Page-Shafer, Amber Cheng, Edwin Charlebois, Robert M Grant, Dennis H Osmond	Travis C Porco	Dennis H Osmond	San Francisco Department of Public Health, Community Health and Epidemiology Section, San Francisco, CA, USA.	NCI NIH HHS; U01-CA78124
Tsui R, Herring BL, Barbour JD, Grant RM, Bacchetti P, Kral A, Edlin BR, Delwart EL	Human immunodeficiency virus type 1 superinfection was not detected following 215 years of injection drug user exposure.	J. Virol.	78:1:94-103	2004	14671091		Rose Tsui, Belinda L Herring, Jason D Barbour, Robert M Grant, Peter Bacchetti, Alex Kral, Brian R Edlin, Eric L Delwart	Rose Tsui	Eric L Delwart	Blood Systems Research Institute, University of California, San Francisco, San Francisco, California, USA.	ODCDC CDC HHS; U64/CCU917889-01
Papasavvas E, Grant RM, Sun J, Mackiewicz A, Pistilli M, Gallo C, Kostman JR, Mounzer K, Shull J, Montaner LJ	Lack of persistent drug-resistant mutations evaluated within and between treatment interruptions in chronically HIV-1-infected patients.	AIDS	17:16:2337-43	2003	14571185		Emmanouil Papasavvas, Robert M Grant, Junwei Sun, Agnieska Mackiewicz, Maxwell Pistilli, Cecile Gallo, Jay R Kostman, Karam Mounzer, Jane Shull, Luis J Montaner	Emmanouil Papasavvas	Luis J Montaner	Wistar Institute and the Philadelphia Field Initiating Group for HIV-1 Trials, Philadelphia, Pennsylvania, USA.	NIAID NIH HHS; AI48398
Bangsberg DR, Charlebois ED, Grant RM, Holodniy M, Deeks SG, Perry S, Conroy KN, Clark R, Guzman D, Zolopa A, Moss A	High levels of adherence do not prevent accumulation of HIV drug resistance mutations.	AIDS	17:13:1925-32	2003	12960825		David R Bangsberg, Edwin D Charlebois, Robert M Grant, Mark Holodniy, Steven G Deeks, Sharon Perry, Kathleen Nugent Conroy, Richard Clark, David Guzman, Andrew Zolopa, Andrew Moss	David R Bangsberg	Andrew Moss	Epidemiology and Prevention Interventions Center, Division of Infectious Diseases, San Francisco General Hospital, California, USA.	NIMH NIH HHS; R01 MH054907
Murphy EL, Grant RM, Kropp J, Oliveira A, Lee TH, Busch MP	Increased human T-lymphotropic virus type II proviral load following highly active retroviral therapy in HIV-coinfected patients.	J. Acquir. Immune Defic. Syndr.	33:5:655-6	2003	12902815		Edward L Murphy, Robert M Grant, Jerry Kropp, Adriano Oliveira, Tzong-Hae Lee, Michael P Busch	Edward L Murphy	Michael P Busch		NHLBI NIH HHS; R01-HL62235
Karlsson AC, Deeks SG, Barbour JD, Heiken BD, Younger SR, Hoh R, Lane M, Sällberg M, Ortiz GM, Demarest JF, Liegler T, Grant RM, Martin JN, Nixon DF	Dual pressure from antiretroviral therapy and cell-mediated immune response on the human immunodeficiency virus type 1 protease gene.	J. Virol.	77:12:6743-52	2003	12767994		Annika C Karlsson, Steven G Deeks, Jason D Barbour, Brandon D Heiken, Sophie R Younger, Rebecca Hoh, Meghan Lane, Matti Sällberg, Gabriel M Ortiz, James F Demarest, Teri Liegler, Robert M Grant, Jeffrey N Martin, Douglas F Nixon	Annika C Karlsson	Douglas F Nixon	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA. akarlsson@gladstone.ucsf.edu	NIMH NIH HHS; P30 MH62246
D'Aquila RT, Schapiro JM, Brun-Vézinet F, Clotet B, Conway B, Demeter LM, Grant RM, Johnson VA, Kuritzkes DR, Loveday C, Shafer RW, Richman DD	Drug resistance mutations in HIV-1.	Top HIV Med	11:3:92-6		12837968		Richard T D'Aquila, Jonathan M Schapiro, Françoise Brun-Vézinet, Bonaventura Clotet, Brian Conway, Lisa M Demeter, Robert M Grant, Victoria A Johnson, Daniel R Kuritzkes, Clive Loveday, Robert W Shafer, Douglas D Richman	Richard T D'Aquila	Douglas D Richman	Vanderbilt University Medical Center, Nashville, TN, USA.	NA
Asmuth DM, Kalish LA, Laycock ME, Murphy EL, Mohr BA, Lee TH, Gallarda J, Giachetti C, Dollard SC, van der Horst CM, Grant RM, Busch MP	Absence of HBV and HCV, HTLV-I and -II, and human herpes virus-8 activation after allogeneic RBC transfusion in patients with advanced HIV-1 infection.	Transfusion	43:4:451-8	2003	12662277		David M Asmuth, Leslie A Kalish, Megan E Laycock, Edward L Murphy, Beth A Mohr, Tzong-Hae Lee, James Gallarda, Cristina Giachetti, Sheila C Dollard, Charles M van der Horst, Robert M Grant, Michael P Busch	David M Asmuth	Michael P Busch	Department of Internal Medicine, Division of Infectious Diseases and Immunology, University of California-Davis Medical Center, 4150 V Street, Suite 6200 PSSB, Sacramento, CA 95817, USA. dasmuth@ucdavis.edu	NCRR NIH HHS; RR 00046
Kuritzkes DR, Grant RM, Feorino P, Griswold M, Hoover M, Young R, Day S, Lloyd Jr RM, Reid C, Morgan GF, Winslow DL	Performance characteristics of the TRUGENE HIV-1 Genotyping Kit and the Opengene DNA Sequencing System.	J. Clin. Microbiol.	41:4:1594-9	2003	12682150		Daniel R Kuritzkes, Robert M Grant, Paul Feorino, Marshal Griswold, Marie Hoover, Russell Young, Stephen Day, Robert M Lloyd Jr, Caroline Reid, Gillian F Morgan, Dean L Winslow	Daniel R Kuritzkes	Dean L Winslow	Division of Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado, USA. dkuritzkes@partners.org	NIAID NIH HHS; U01 AI-38858
Grant RM, Kuritzkes DR, Johnson VA, Mellors JW, Sullivan JL, Swanstrom R, D'Aquila RT, Van Gorder M, Holodniy M, Lloyd Jr RM, Reid C, Morgan GF, Winslow DL	Accuracy of the TRUGENE HIV-1 genotyping kit.	J. Clin. Microbiol.	41:4:1586-93	2003	12682149		Robert M Grant, Daniel R Kuritzkes, Victoria A Johnson, John W Mellors, John L Sullivan, Ronald Swanstrom, Richard T D'Aquila, Mark Van Gorder, Mark Holodniy, Robert M Lloyd Jr, Caroline Reid, Gillian F Morgan, Dean L Winslow	Robert M Grant	Dean L Winslow	Gladstone Institute of Virology and Immunology, San Francisco, CA 94141, USA. rgrant@itsa.ucsf.edu	NA
Hayden MS, Palacios EH, Grant RM	Real-time quantitation of HIV-1 p24 and SIV p27 using fluorescence-linked antigen quantification assays.	AIDS	17:4:629-31	2003	12598787		Matthew S Hayden, Emil H Palacios, Robert M Grant	Matthew S Hayden	Robert M Grant	Gladstone Institute of Virology and Immunology, San Francisco, CA, USA.	NCRR NIH HHS; P51-RR-00165-31
Deeks SG, Grant RM, Wrin T, Paxinos EE, Liegler T, Hoh R, Martin JN, Petropoulos CJ	Persistence of drug-resistant HIV-1 after a structured treatment interruption and its impact on treatment response.	AIDS	17:3:361-70	2003	12556690		Steven G Deeks, Robert M Grant, Terri Wrin, Ellen E Paxinos, Teri Liegler, Rebecca Hoh, Jeff N Martin, Christos J Petropoulos	Steven G Deeks	Christos J Petropoulos	University of California-San Francisco and San Francisco General Hospital, 995 Potrero Avenue, San Francisco, CA 94110, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH 59037
Schweighardt B, Ortiz GM, Grant RM, Wellons M, Miralles GD, Kostrikis LG, Bartlett JA, Nixon DF	Emergence of drug-resistant HIV-1 variants in patients undergoing structured treatment interruptions.	AIDS	16:17:2342-4	2002	12441810		Becky Schweighardt, Gabriel M Ortiz, Robert M Grant, Melissa Wellons, G Diego Miralles, Leondios G Kostrikis, John A Bartlett, Douglas F Nixon	Becky Schweighardt	Douglas F Nixon	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA, USA.	NIAID NIH HHS; R01 AI44595
Barbour JD, Wrin T, Grant RM, Martin JN, Segal MR, Petropoulos CJ, Deeks SG	Evolution of phenotypic drug susceptibility and viral replication capacity during long-term virologic failure of protease inhibitor therapy in human immunodeficiency virus-infected adults.	J. Virol.	76:21:11104-12	2002	12368352		Jason D Barbour, Terri Wrin, Robert M Grant, Jeffrey N Martin, Mark R Segal, Christos J Petropoulos, Steven G Deeks	Jason D Barbour	Steven G Deeks	Gladstone Institute of Virology and Immunology, Department of Medicine, University of California, San Francisco, California, USA.	NIMH NIH HHS; P30 MH59037
Neuenburg JK, Brodt HR, Herndier BG, Bickel M, Bacchetti P, Price RW, Grant RM, Schlote W	HIV-related neuropathology, 1985 to 1999: rising prevalence of HIV encephalopathy in the era of highly active antiretroviral therapy.	J. Acquir. Immune Defic. Syndr.	31:2:171-7	2002	12394795		Jutta K Neuenburg, Hans R Brodt, Brian G Herndier, Markus Bickel, Peter Bacchetti, Richard W Price, Robert M Grant, Wolfgang Schlote	Jutta K Neuenburg	Wolfgang Schlote	Department of Neurology, University of California, San Francisco, USA. jneuenburg@gladstone.ucsf.edu	NINDS NIH HHS; R01 NS37660
Sandberg JK, Fast NM, Palacios EH, Fennelly G, Dobroszycki J, Palumbo P, Wiznia A, Grant RM, Bhardwaj N, Rosenberg MG, Nixon DF	Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection.	J. Virol.	76:15:7528-34	2002	12097565		Johan K Sandberg, Noam M Fast, Emil H Palacios, Glenn Fennelly, Joanna Dobroszycki, Paul Palumbo, Andrew Wiznia, Robert M Grant, Nina Bhardwaj, Michael G Rosenberg, Douglas F Nixon	Johan K Sandberg	Douglas F Nixon	Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94141, USA.	NIAID NIH HHS; AI44595
Grant RM, Hecht FM, Warmerdam M, Liu L, Liegler T, Petropoulos CJ, Hellmann NS, Chesney M, Busch MP, Kahn JO	Time trends in primary HIV-1 drug resistance among recently infected persons.	JAMA	288:2:181-8	2002	12095382		Robert M Grant, Frederick M Hecht, Maria Warmerdam, Lea Liu, Teri Liegler, Christos J Petropoulos, Nicholas S Hellmann, Margaret Chesney, Michael P Busch, James O Kahn	Robert M Grant	James O Kahn	Gladstone Institute of Virology and Immunology, PO Box 914100, San Francisco, CA 94141, USA. rgrant@itsa.ucsf.edu	ODCDC CDC HHS; U64/CCU913941
Napolitano LA, Lo JC, Gotway MB, Mulligan K, Barbour JD, Schmidt D, Grant RM, Halvorsen RA, Schambelan M, McCune JM	Increased thymic mass and circulating naive CD4 T cells in HIV-1-infected adults treated with growth hormone.	AIDS	16:8:1103-11	2002	12004268		Laura A Napolitano, Joan C Lo, Michael B Gotway, Kathleen Mulligan, Jason D Barbour, Diane Schmidt, Robert M Grant, Robert A Halvorsen, Morris Schambelan, Joseph M McCune	Laura A Napolitano	Joseph M McCune	Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, CA 94141, USA.	NCRR NIH HHS; RR00083-39S1
Grant R, Walker M, Hadley D, Barton T, Osborn C	Imaging response to chemotherapy with RMP-7 and carboplatin in malignant glioma: size matters but speed does not.	J. Neurooncol.	57:3:241-5	2002	12125987		Robert Grant, Mark Walker, Donald Hadley, Tina Barton, Chester Osborn	Robert Grant	Chester Osborn	Edinburgh Centre for Neuro-Oncology, Western General Hospital, Scotland, UK. Rgrant@skull.dcn.ed.ac.uk	NA
Deeks SG, Barbour JD, Grant RM, Martin JN	Duration and predictors of CD4 T-cell gains in patients who continue combination therapy despite detectable plasma viremia.	AIDS	16:2:201-7	2002	11807304		Steven G Deeks, Jason D Barbour, Robert M Grant, Jeffrey N Martin	Steven G Deeks	Jeffrey N Martin	UCSF AIDS Program, University of California and San Francisco General Hospital, San Francisco, California 94110, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH59037
Deeks SG, Hoh R, Grant RM, Wrin T, Barbour JD, Narvaez A, Cesar D, Abe K, Hanley MB, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK	CD4+ T cell kinetics and activation in human immunodeficiency virus-infected patients who remain viremic despite long-term treatment with protease inhibitor-based therapy.	J. Infect. Dis.	185:3:315-23	2002	11807713		Steven G Deeks, Rebecca Hoh, Robert M Grant, Terri Wrin, Jason D Barbour, Amy Narvaez, Denise Cesar, Ken Abe, Mary Beth Hanley, Nicholas S Hellmann, Christos J Petropoulos, Joseph M McCune, Marc K Hellerstein	Steven G Deeks	Marc K Hellerstein	Department of Medicine, University of California at San Francisco and San Francisco General Hospital, San Francisco, CA 94110, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH59037
Roland ME, Martin JN, Grant RM, Hellmann NS, Bamberger JD, Katz MH, Chesney M, Franses K, Coates TJ, Kahn JO	Postexposure prophylaxis for human immunodeficiency virus infection after sexual or injection drug use exposure: identification and characterization of the source of exposure.	J. Infect. Dis.	184:12:1608-12	2001	11740738		M E Roland, J N Martin, R M Grant, N S Hellmann, J D Bamberger, M H Katz, M Chesney, K Franses, T J Coates, J O Kahn	M E Roland	J O Kahn	University of California at San Francisco, Div. of AIDS, Dept. of Medicine, San Francisco General Hospital, San Francisco, CA 94110, USA. mroland@php.ucsf.edu	NIMH NIH HHS; P30 MH59037
Price RW, Paxinos EE, Grant RM, Drews B, Nilsson A, Hoh R, Hellmann NS, Petropoulos CJ, Deeks SG	Cerebrospinal fluid response to structured treatment interruption after virological failure.	AIDS	15:10:1251-9	2001	11426069		R W Price, E E Paxinos, R M Grant, B Drews, A Nilsson, R Hoh, N S Hellmann, C J Petropoulos, S G Deeks	R W Price	S G Deeks	Department of Neurology, University of California San Francisco and San Francisco General Hospital, 94110-3518, USA. price@itsa.ucsf.edu	NINDS NIH HHS; R01 NS37660
Stoddart CA, Liegler TJ, Mammano F, Linquist-Stepps VD, Hayden MS, Deeks SG, Grant RM, Clavel F, McCune JM	Impaired replication of protease inhibitor-resistant HIV-1 in human thymus.	Nat. Med.	7:6:712-8	2001	11385509		C A Stoddart, T J Liegler, F Mammano, V D Linquist-Stepps, M S Hayden, S G Deeks, R M Grant, F Clavel, J M McCune	C A Stoddart	J M McCune	Gladstone Institute of Virology and Immunology, University of California at San Francisco, San Francisco, California, USA.	NIMH NIH HHS; P30 MH59037
Penn ML, Myers M, Eckstein DA, Liegler TJ, Hayden M, Mammano F, Clavel F, Deeks SG, Grant RM, Goldsmith MA	Primary and recombinant HIV type 1 strains resistant to protease inhibitors are pathogenic in mature human lymphoid tissues.	AIDS Res. Hum. Retroviruses	17:6:517-23	2001	11350665		M L Penn, M Myers, D A Eckstein, T J Liegler, M Hayden, F Mammano, F Clavel, S G Deeks, R M Grant, M A Goldsmith	M L Penn	M A Goldsmith	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, CA 94141, USA.	NCI NIH HHS; R01-CA86814
Deeks SG, Wrin T, Liegler T, Hoh R, Hayden M, Barbour JD, Hellmann NS, Petropoulos CJ, McCune JM, Hellerstein MK, Grant RM	Virologic and immunologic consequences of discontinuing combination antiretroviral-drug therapy in HIV-infected patients with detectable viremia.	N. Engl. J. Med.	344:7:472-80	2001	11172188		S G Deeks, T Wrin, T Liegler, R Hoh, M Hayden, J D Barbour, N S Hellmann, C J Petropoulos, J M McCune, M K Hellerstein, R M Grant	S G Deeks	R M Grant	University of California, San Francisco, and San Francisco General Hospital, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH59037
Napolitano LA, Grant RM, Deeks SG, Schmidt D, De Rosa SC, Herzenberg LA, Herndier BG, Andersson J, McCune JM	Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis.	Nat. Med.	7:1:73-9	2001	11135619		L A Napolitano, R M Grant, S G Deeks, D Schmidt, S C De Rosa, L A Herzenberg, B G Herndier, J Andersson, J M McCune	L A Napolitano	J M McCune	Gladstone Institute of Virology and Immunology, San Francisco General Hospital, and Department of Medicine, University of California at San Francisco, San Francisco, California 94110-9100, USA.	NCI NIH HHS; CA66529
Parkin NT, Deeks SG, Wrin MT, Yap J, Grant RM, Lee KH, Heeren D, Hellmanna NS, Petropoulos CJ	Loss of antiretroviral drug susceptibility at low viral load during early virological failure in treatment-experienced patients.	AIDS	14:18:2877-87	2000	11153669		N T Parkin, S G Deeks, M T Wrin, J Yap, R M Grant, K H Lee, D Heeren, N S Hellmanna, C J Petropoulos	N T Parkin	C J Petropoulos	ViroLogic Inc., South San Francisco, California 94080, USA. nparkin@virologic.com	NIMH NIH HHS; P30 MH59037
Celum CL, Buchbinder SP, Donnell D, Douglas JM, Mayer K, Koblin B, Marmor M, Bozeman S, Grant RM, Flores J, Sheppard HW	Early human immunodeficiency virus (HIV) infection in the HIV Network for Prevention Trials Vaccine Preparedness Cohort: risk behaviors, symptoms, and early plasma and genital tract virus load.	J. Infect. Dis.	183:1:23-35	2001	11106536		C L Celum, S P Buchbinder, D Donnell, J M Douglas, K Mayer, B Koblin, M Marmor, S Bozeman, R M Grant, J Flores, H W Sheppard	C L Celum	H W Sheppard	University of Washington HIV Prevention Trials Unit, Harborview Medical Center, Seattle, WA 98104, USA. ccelum@u.washington.edu	NIAID NIH HHS; AI-45202
Schramm B, Penn ML, Palacios EH, Grant RM, Kirchhoff F, Goldsmith MA	Cytopathicity of human immunodeficiency virus type 2 (HIV-2) in human lymphoid tissue is coreceptor dependent and comparable to that of HIV-1.	J. Virol.	74:20:9594-600	2000	11000231		B Schramm, M L Penn, E H Palacios, R M Grant, F Kirchhoff, M A Goldsmith	B Schramm	M A Goldsmith	Gladstone Institute of Virology and Immunology, University of California San Francisco, San Francisco, California 94141-91000, USA.	NIAID NIH HHS; R01-AI43695
Huang SS, Barbour JD, Deeks SG, Huang JS, Grant RM, Ng VL, McCune JM	Reversal of human immunodeficiency virus type 1-associated hematosuppression by effective antiretroviral therapy.	Clin. Infect. Dis.	30:3:504-10	2000	10722435		S S Huang, J D Barbour, S G Deeks, J S Huang, R M Grant, V L Ng, J M McCune	S S Huang	J M McCune	Department of Medicine, University of California at San Francisco and San Francisco General Hospital, San Francisco, CA, USA.	NIAID NIH HHS; R01AI40312
Deeks SG, Barbour JD, Martin JN, Swanson MS, Grant RM	Sustained CD4+ T cell response after virologic failure of protease inhibitor-based regimens in patients with human immunodeficiency virus infection.	J. Infect. Dis.	181:3:946-53	2000	10720517		S G Deeks, J D Barbour, J N Martin, M S Swanson, R M Grant	S G Deeks	R M Grant	University of California, San Francisco, AIDS Program, San Francisco General Hospital, San Francisco, CA 94110, USA. sdeeks@php.ucsf.edu	NIMH NIH HHS; P30 MH59037
Blower SM, Gershengorn HB, Grant RM	A tale of two futures: HIV and antiretroviral therapy in San Francisco.	Science	287:5453:650-4	2000	10649998		S M Blower, H B Gershengorn, R M Grant	S M Blower	R M Grant	Department of Medicine, University of California San Francisco, 513 Parnassus, Box 0414, San Francisco, CA 94143-0414, USA. sally@itsa.ucsf.edu	NIMH NIH HHS; P30-MH59037
Greenblatt RM, Ameli N, Grant RM, Bacchetti P, Taylor RN	Impact of the ovulatory cycle on virologic and immunologic markers in HIV-infected women.	J. Infect. Dis.	181:1:82-90	2000	10608754		R M Greenblatt, N Ameli, R M Grant, P Bacchetti, R N Taylor	R M Greenblatt	R N Taylor	University of California, Infectious Diseases Division, San Francisco, CA 94122, USA. ruthg@itsa.ucsf.edu ruthg@itsa.ucsf.edu	NIAID NIH HHS; UO1-AI-34989
Locher CP, Grant RM, Collisson EA, Reyes-Terán G, Elbeik T, Kahn JO, Levy JA	Antibody and cellular immune responses in breakthrough infection subjects after HIV type 1 glycoprotein 120 vaccination.	AIDS Res. Hum. Retroviruses	15:18:1685-9	1999	10606091		C P Locher, R M Grant, E A Collisson, G Reyes-Terán, T Elbeik, J O Kahn, J A Levy	C P Locher	J A Levy	Department of Medicine, University of California, San Francisco 94143, USA.	NIAID NIH HHS; P30 AI27763-08
Staprans S, Marlowe N, Glidden D, Novakovic-Agopian T, Grant RM, Heyes M, Aweeka F, Deeks S, Price RW	Time course of cerebrospinal fluid responses to antiretroviral therapy: evidence for variable compartmentalization of infection.	AIDS	13:9:1051-61	1999	10397535		S Staprans, N Marlowe, D Glidden, T Novakovic-Agopian, R M Grant, M Heyes, F Aweeka, S Deeks, R W Price	S Staprans	R W Price	Department of Medicine, University of California, San Francisco, USA.	NINDS NIH HHS; R01 NS37660
Staprans SI, Dailey PJ, Rosenthal A, Horton C, Grant RM, Lerche N, Feinberg MB	Simian immunodeficiency virus disease course is predicted by the extent of virus replication during primary infection.	J. Virol.	73:6:4829-39	1999	10233944		S I Staprans, P J Dailey, A Rosenthal, C Horton, R M Grant, N Lerche, M B Feinberg	S I Staprans	M B Feinberg	Department of Medicine-AIDS Program, University of California, San Francisco, San Francisco, California 94110, USA.	NIAID NIH HHS; P30 AI27763
Deeks SG, Hellmann NS, Grant RM, Parkin NT, Petropoulos CJ, Becker M, Symonds W, Chesney M, Volberding PA	Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome.	J. Infect. Dis.	179:6:1375-81	1999	10228057		S G Deeks, N S Hellmann, R M Grant, N T Parkin, C J Petropoulos, M Becker, W Symonds, M Chesney, P A Volberding	S G Deeks	P A Volberding	University of California, San Francisco, AIDS Program. San Francisco General Hospital, San Francisco General Hospital, San Francisco, CA 94110, USA. sdeeks@sfaids.ucsf.edu	NIAID NIH HHS; AI-27763
Deeks SG, Hecht FM, Swanson M, Elbeik T, Loftus R, Cohen PT, Grant RM	HIV RNA and CD4 cell count response to protease inhibitor therapy in an urban AIDS clinic: response to both initial and salvage therapy.	AIDS	13:6:F35-43	1999	10397555		S G Deeks, F M Hecht, M Swanson, T Elbeik, R Loftus, P T Cohen, R M Grant	S G Deeks	R M Grant	University of California, San Francisco and San Francisco General Hospital, 94110, USA. sdeeks@sfaids.ucsf.edu	NIAID NIH HHS; P30 AI27763
Deeks SG, Grant RM	Sustained CD4 responses after virological failure of protease inhibitor-containing therapy.	Antivir. Ther. (Lond.)	4 Suppl 3:7-11	1999	16021865		S G Deeks, R M Grant	S G Deeks	R M Grant	University of California and San Francisco General Hospital, San Francisco, California, USA. sdeeks@php.ucsf.edu	NA
Kaur A, Grant RM, Means RE, McClure H, Feinberg M, Johnson RP	Diverse host responses and outcomes following simian immunodeficiency virus SIVmac239 infection in sooty mangabeys and rhesus macaques.	J. Virol.	72:12:9597-611	1998	9811693		A Kaur, R M Grant, R E Means, H McClure, M Feinberg, R P Johnson	A Kaur	R P Johnson	Divisions of Immunology, New England Regional Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA.	NCRR NIH HHS; RR 0165
Hecht FM, Grant RM, Petropoulos CJ, Dillon B, Chesney MA, Tian H, Hellmann NS, Bandrapalli NI, Digilio L, Branson B, Kahn JO	Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors.	N. Engl. J. Med.	339:5:307-11	1998	9682043		F M Hecht, R M Grant, C J Petropoulos, B Dillon, M A Chesney, H Tian, N S Hellmann, N I Bandrapalli, L Digilio, B Branson, J O Kahn	F M Hecht	J O Kahn	AIDS Program, San Francisco General Hospital and University of California, 94110, USA.	PHS HHS; UO1 41531
Deeks SG, Grant RM, Beatty GW, Horton C, Detmer J, Eastman S	Activity of a ritonavir plus saquinavir-containing regimen in patients with virologic evidence of indinavir or ritonavir failure.	AIDS	12:10:F97-102	1998	9677159		S G Deeks, R M Grant, G W Beatty, C Horton, J Detmer, S Eastman	S G Deeks	S Eastman	University of California, San Francisco and San Francisco General Hospital, 94110, USA.	NIAID NIH HHS; P30 AI27763
Palacios E, Digilio L, McClure HM, Chen Z, Marx PA, Goldsmith MA, Grant RM	Parallel evolution of CCR5-null phenotypes in humans and in a natural host of simian immunodeficiency virus.	Curr. Biol.	8:16:943-6		9707408		E Palacios, L Digilio, H M McClure, Z Chen, P A Marx, M A Goldsmith, R M Grant	E Palacios	R M Grant	Gladstone Institute of Virology and Immunology San Francisco, California, USA.	PHS HHS; R21-A142654-01
McCune JM, Loftus R, Schmidt DK, Carroll P, Webster D, Swor-Yim LB, Francis IR, Gross BH, Grant RM	High prevalence of thymic tissue in adults with human immunodeficiency virus-1 infection.	J. Clin. Invest.	101:11:2301-8	1998	9616201		J M McCune, R Loftus, D K Schmidt, P Carroll, D Webster, L B Swor-Yim, I R Francis, B H Gross, R M Grant	J M McCune	R M Grant	The Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, California 94141-9100, USA. Mike_McCune.givi@quickmail.ucsf.edu	NIAID NIH HHS; R01-AI40312
Grant RM, Abrams DI	Not all is dead in HIV-1 graveyard.	Lancet	351:9099:308-9	1998	9652607		R M Grant, D I Abrams	R M Grant	D I Abrams	Gladstone Institute of Virology and Immunology, and AIDS Program, University of California, San Francisco, 94110, USA.	NA
Grant RM, Piwowar EM, Katongole-Mbidde E, Muzawalu W, Rugera S, Abima J, Stramer SL, Kataaha P, Jackson B	Comparison of saliva and serum for human immunodeficiency virus type 1 antibody testing in Uganda using a rapid recombinant assay.	Clin. Diagn. Lab. Immunol.	3:6:640-4	1996	8914752		R M Grant, E M Piwowar, E Katongole-Mbidde, W Muzawalu, S Rugera, J Abima, S L Stramer, P Kataaha, B Jackson	R M Grant	B Jackson	University of California, San Francisco, USA. rgrant@hsa.uscf.edu	NIAID NIH HHS; AI-32395
Chuck S, Grant RM, Katongole-Mbidde E, Conant M, Ganem D	Frequent presence of a novel herpesvirus genome in lesions of human immunodeficiency virus-negative Kaposi's sarcoma.	J. Infect. Dis.	173:1:248-51	1996	8537669		S Chuck, R M Grant, E Katongole-Mbidde, M Conant, D Ganem	S Chuck	D Ganem	Howard Hughes Medical Institute, University of California, San Francisco 94143, USA.	NA
Staprans SI, Hamilton BL, Follansbee SE, Elbeik T, Barbosa P, Grant RM, Feinberg MB	Activation of virus replication after vaccination of HIV-1-infected individuals.	J. Exp. Med.	182:6:1727-37	1995	7500017		S I Staprans, B L Hamilton, S E Follansbee, T Elbeik, P Barbosa, R M Grant, M B Feinberg	S I Staprans	M B Feinberg	Gladstone Institute of Virology and Immunology, San Francisco, California 94141, USA.	NA
Kamya MR, Nsubuga P, Grant RM, Hellman N	The high prevalence of genital herpes among patients with genital ulcer disease in Uganda.	Sex Transm Dis	22:6:351-4		8578407		M R Kamya, P Nsubuga, R M Grant, N Hellman	M R Kamya	N Hellman	Department of Medicine, School of Medicine, Makerere University, Kampala, Uganda.	NA
Tsai CC, Follis KE, Sabo A, Grant R, Bischofberger N	Efficacy of 9-(2-phosphonylmethoxyethyl)adenine treatment against chronic simian immunodeficiency virus infection in macaques.	J. Infect. Dis.	171:5:1338-43	1995	7538551		C C Tsai, K E Follis, A Sabo, R Grant, N Bischofberger	C C Tsai	N Bischofberger	Regional Primate Research Center, University of Washington, Seattle 99022, USA.	NCRR NIH HHS; RR-00166
Tugume SB, Piwowar EM, Lutalo T, Mugyenyi PN, Grant RM, Mangeni FW, Pattishall K, Katongole-Mbidde E	Hematological reference ranges among healthy Ugandans.	Clin. Diagn. Lab. Immunol.	2:2:233-5	1995	7697535		S B Tugume, E M Piwowar, T Lutalo, P N Mugyenyi, R M Grant, F W Mangeni, K Pattishall, E Katongole-Mbidde	S B Tugume	E Katongole-Mbidde	Joint Clinical Research Centre, Makerere University Medical School, Kampala, Uganda.	NIAID NIH HHS; AI-32395
Piwowar EM, Tugume SB, Grant RM, Lutalo T, Pattishall K, Katongole-Mbidde E	beta-2 Microglobulin values among human immunodeficiency virus (HIV)-negative, HIV-positive asymptomatic, and HIV-positive symptomatic Ugandans.	Clin. Diagn. Lab. Immunol.	2:2:236-7	1995	7697536		E M Piwowar, S B Tugume, R M Grant, T Lutalo, K Pattishall, E Katongole-Mbidde	E M Piwowar	E Katongole-Mbidde	University Hospitals of Cleveland, Ohio.	NIAID NIH HHS; AI-32395
Tan M, Klein R, Grant R, Ganem D, Engel J	Cloning and characterization of the RNA polymerase alpha-subunit operon of Chlamydia trachomatis.	J. Bacteriol.	175:22:7150-9	1993	8226662		M Tan, R Klein, R Grant, D Ganem, J Engel	M Tan	J Engel	Department of Microbiology and Immunology, University of California, San Francisco 94143.	NIAID NIH HHS; AI24436
Erlich KS, Mills J, Chatis P, Mertz GJ, Busch DF, Follansbee SE, Grant RM, Crumpacker CS	Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome.	N. Engl. J. Med.	320:5:293-6	1989	2536136		K S Erlich, J Mills, P Chatis, G J Mertz, D F Busch, S E Follansbee, R M Grant, C S Crumpacker	K S Erlich	C S Crumpacker	Department of Medicine, University of California, San Francisco.	NIAID NIH HHS; 5-T32-AI07234
Grant R, Hadley DM, Lang D, Condon B, Johnston R, Bone I, Teasdale GM	MRI measurement of syrinx size before and after operation.	J. Neurol. Neurosurg. Psychiatr.	50:12:1685-7	1987	3437304		R Grant, D M Hadley, D Lang, B Condon, R Johnston, I Bone, G M Teasdale	R Grant	G M Teasdale	Magnetic Resonance Unit, Southern General Hospital, Glasgow, UK.	NA
Grant RM, Wiley JA, Winkelstein W	Infectivity of the human immunodeficiency virus: estimates from a prospective study of homosexual men.	J. Infect. Dis.	156:1:189-93	1987	3474298		R M Grant, J A Wiley, W Winkelstein	R M Grant	W Winkelstein		NIAID NIH HHS; AI-32519
Winkelstein W, Lyman DM, Padian N, Grant R, Samuel M, Wiley JA, Anderson RE, Lang W, Riggs J, Levy JA	Sexual practices and risk of infection by the human immunodeficiency virus. The San Francisco Men's Health Study.	JAMA	257:3:321-5	1987	3540327		W Winkelstein, D M Lyman, N Padian, R Grant, M Samuel, J A Wiley, R E Anderson, W Lang, J Riggs, J A Levy	W Winkelstein	J A Levy		NIAID NIH HHS; N01-AI-32519
Lang W, Anderson RE, Perkins H, Grant RM, Lyman D, Winkelstein W, Royce R, Levy JA	Clinical, immunologic, and serologic findings in men at risk for acquired immunodeficiency syndrome. The San Francisco Men's Health Study.	JAMA	257:3:326-30	1987	3491910		W Lang, R E Anderson, H Perkins, R M Grant, D Lyman, W Winkelstein, R Royce, J A Levy	W Lang	J A Levy		NIAID NIH HHS; N01-AI-32519
Ott M, Geyer M, Zhou Q	The control of HIV transcription: keeping RNA polymerase II on track.	Cell Host Microbe	10:5:426-35	2011	22100159		Melanie Ott, Matthias Geyer, Qiang Zhou	Melanie Ott	Qiang Zhou	Gladstone Institutes of Virology and Immunology, University of California, San Francisco, 94158, USA. mott@gladstone.ucsf.edu	NIAID NIH HHS; R01AI41757
Herker E, Ott M	Emerging role of lipid droplets in host/pathogen interactions.	J. Biol. Chem.	287:4:2280-7	2012	22090026		Eva Herker, Melanie Ott	Eva Herker	Melanie Ott	Gladstone Institute of Virology and Immunology, San Francisco, California 94158, USA.	NIAID NIH HHS; R56 AI085056
Herker E, Ott M	Unique ties between hepatitis C virus replication and intracellular lipids.	Trends Endocrinol. Metab.	22:6:241-8	2011	21497514		Eva Herker, Melanie Ott	Eva Herker	Melanie Ott	Gladstone Institute of Virology and Immunology, 1650 Owens Street, San Francisco, CA 94158, USA.	NIAID NIH HHS; R56 AI085056-01
Min SW, Cho SH, Zhou Y, Schroeder S, Haroutunian V, Seeley WW, Huang EJ, Shen Y, Masliah E, Mukherjee C, Meyers D, Cole PA, Ott M, Gan L	Acetylation of tau inhibits its degradation and contributes to tauopathy.	Neuron	67:6:953-66	2010	20869593		Sang-Won Min, Seo-Hyun Cho, Yungui Zhou, Sebastian Schroeder, Vahram Haroutunian, William W Seeley, Eric J Huang, Yong Shen, Eliezer Masliah, Chandrani Mukherjee, David Meyers, Philip A Cole, Melanie Ott, Li Gan	Sang-Won Min	Li Gan	Gladstone Institute of Neurological Disease, San Francisco, CA 94158, USA.	NIA NIH HHS; R01 AG030207-01A2
Pagans S, Sakane N, Schnölzer M, Ott M	Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies.	Methods	53:1:91-6	2011	20615470		Sara Pagans, Naoki Sakane, Martina Schnölzer, Melanie Ott	Sara Pagans	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; R01AI083139
Cho S, Schroeder S, Ott M	CYCLINg through transcription: posttranslational modifications of P-TEFb regulate transcription elongation.	Cell Cycle	9:9:1697-705	2010	20436276		Sungyoo Cho, Sebastian Schroeder, Melanie Ott	Sungyoo Cho	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, San Francisco, CA, USA.	NIAID NIH HHS; R01 AI083139-03
Cho S, Schroeder S, Kaehlcke K, Kwon HS, Pedal A, Herker E, Schnoelzer M, Ott M	Acetylation of cyclin T1 regulates the equilibrium between active and inactive P-TEFb in cells.	EMBO J.	28:10:1407-17	2009	19387490		Sungyoo Cho, Sebastian Schroeder, Katrin Kaehlcke, Hye-Sook Kwon, Angelika Pedal, Eva Herker, Martina Schnoelzer, Melanie Ott	Sungyoo Cho	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NIAID NIH HHS; R56 AI067118-01A2
Kwon HS, Ott M	The ups and downs of SIRT1.	Trends Biochem. Sci.	33:11:517-25	2008	18805010		Hye-Sook Kwon, Melanie Ott	Hye-Sook Kwon	Melanie Ott	Gladstone Institute of Virology and Immunology, University of California, San Francisco, CA 94158, USA.	NA
Ishigame H, Zenewicz LA, Sanjabi S, Licona-Limón P, Nakayama M, Leonard WJ, Flavell RA	Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis.	Proc. Natl. Acad. Sci. U.S.A.	110:17:6961-6	2013	23569233		Harumichi Ishigame, Lauren A Zenewicz, Shomyseh Sanjabi, Paula Licona-Limón, Maki Nakayama, Warren J Leonard, Richard A Flavell	Harumichi Ishigame	Richard A Flavell	Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.	Howard Hughes Medical Institute; 
Flavell RA, Sanjabi S, Wrzesinski SH, Licona-Limón P	The polarization of immune cells in the tumour environment by TGFbeta.	Nat. Rev. Immunol.	10:8:554-67	2010	20616810		Richard A Flavell, Shomyseh Sanjabi, Stephen H Wrzesinski, Paula Licona-Limón	Richard A Flavell	Paula Licona-Limón	Yale University School of Medicine, 300 Cedar Street, TAC S-569, PO BOX 208011, New Haven, Connecticut 06520, USA. richard.flavell@yale.edu	Howard Hughes Medical Institute; 
Sanjabi S, Flavell RA	Interaction between TGFbeta and the common gamma chain cytokines during an inflammatory immune response.	Cell Cycle	9:3:428-30	2010	20107324		Shomyseh Sanjabi, Richard A Flavell	Shomyseh Sanjabi	Richard A Flavell		NA
Sanjabi S, Flavell RA	Overcoming the hurdles in using mouse genetic models that block TGF-beta signaling.	J. Immunol. Methods	353:1-2:111-4	2010	20060833		Shomyseh Sanjabi, Richard A Flavell	Shomyseh Sanjabi	Richard A Flavell	Yale University School of Medicine, New Haven, CT 06520, USA.	Howard Hughes Medical Institute; 
Sanjabi S, Mosaheb MM, Flavell RA	Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells.	Immunity	31:1:131-44	2009	19604492		Shomyseh Sanjabi, Munir M Mosaheb, Richard A Flavell	Shomyseh Sanjabi	Richard A Flavell	Yale University School of Medicine, New Haven, CT 06520, USA.	Howard Hughes Medical Institute; 
Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, Flavell RA	Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis.	Proc. Natl. Acad. Sci. U.S.A.	106:24:9785-90	2009	19497879		Didi Matza, Abdallah Badou, Mithilesh K Jha, Tim Willinger, Andrey Antov, Shomyseh Sanjabi, Koichi S Kobayashi, Vincent T Marchesi, Richard A Flavell	Didi Matza	Richard A Flavell	Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06510, USA.	Howard Hughes Medical Institute; 
Sanjabi S, Zenewicz LA, Kamanaka M, Flavell RA	Anti-inflammatory and pro-inflammatory roles of TGF-beta, IL-10, and IL-22 in immunity and autoimmunity.	Curr Opin Pharmacol	9:4:447-53	2009	19481975		Shomyseh Sanjabi, Lauren A Zenewicz, Masahito Kamanaka, Richard A Flavell	Shomyseh Sanjabi	Richard A Flavell	Yale School of Medicine, New Haven, CT 06520, USA.	Howard Hughes Medical Institute; 
Fu YQ, Sanjabi S, Barber ZH, Huang WM, Cai M, Zhang S, Luo JK, Flewitt AJ, Milne WI	In-situ observation of transition between surface relief and wrinkling in thin film shape memory alloys.	J Nanosci Nanotechnol	8:5:2588-96	2008	18572689		Y Q Fu, S Sanjabi, Z H Barber, W M Huang, M Cai, S Zhang, J K Luo, A J Flewitt, W I Milne	Y Q Fu	W I Milne	Department of Engineering, Cambridge University, 9 JJ Thomson Ave, Cambridge, CB3, 0FA, UK.	NA
Wang J, Wang X, Hussain S, Zheng Y, Sanjabi S, Ouaaz F, Beg AA	Distinct roles of different NF-kappa B subunits in regulating inflammatory and T cell stimulatory gene expression in dendritic cells.	J. Immunol.	178:11:6777-88	2007	17513725		Junmei Wang, Xingyu Wang, Sofia Hussain, Ye Zheng, Shomyseh Sanjabi, Fatah Ouaaz, Amer A Beg	Junmei Wang	Amer A Beg	Department of Interdisciplinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, University of South Florida, Tampa, FL 33612, USA.	NIAID NIH HHS; R01 AI059715
Li MO, Sanjabi S, Flavell RA	Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms.	Immunity	25:3:455-71	2006	16973386		Ming O Li, Shomyseh Sanjabi, Richard A Flavell	Ming O Li	Richard A Flavell	Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA.	NIDDK NIH HHS; R01DK51665
Kriegel MA, Li MO, Sanjabi S, Wan YY, Flavell RA	Transforming growth factor-beta: recent advances on its role in immune tolerance.	Curr Rheumatol Rep	8:2:138-44	2006	16569373		Martin A Kriegel, Ming O Li, Shomyseh Sanjabi, Yisong Y Wan, Richard A Flavell	Martin A Kriegel	Richard A Flavell	Howard Hughes Medical Institute, Yale University School of Medicine, Section of Immunobiology, New Haven, CT 06520, USA.	NIDDK NIH HHS; DK53015
Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA	Transforming growth factor-beta regulation of immune responses.	Annu. Rev. Immunol.	24:99-146	2006	16551245		Ming O Li, Yisong Y Wan, Shomyseh Sanjabi, Anna-Karin L Robertson, Richard A Flavell	Ming O Li	Richard A Flavell	Section of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520, USA. ming.li@yale.edu	NIAMS NIH HHS; R01 AR060723-03
Dong C, Sanjabi S, Eynon E	Gene regulation and function: its rocking science.	Immunity	23:6:557-60	2005	16392168		Chen Dong, Shomyseh Sanjabi, Elizabeth Eynon	Chen Dong	Elizabeth Eynon	Department of Immunology MD Anderson Cancer Center, Houston, Texas 77030, USA. cdong@mdanderson.org	NA
Sanjabi S, Williams KJ, Saccani S, Zhou L, Hoffmann A, Ghosh G, Gerondakis S, Natoli G, Smale ST	A c-Rel subdomain responsible for enhanced DNA-binding affinity and selective gene activation.	Genes Dev.	19:18:2138-51	2005	16166378		Shomyseh Sanjabi, Kevin J Williams, Simona Saccani, Liang Zhou, Alexander Hoffmann, Gourisankar Ghosh, Steve Gerondakis, Gioacchino Natoli, Stephen T Smale	Shomyseh Sanjabi	Stephen T Smale	Howard Hughes Medical Institute, Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095-1662, USA.	NCI NIH HHS; T32-CA09120
Weinmann AS, Mitchell DM, Sanjabi S, Bradley MN, Hoffmann A, Liou HC, Smale ST	Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event.	Nat. Immunol.	2:1:51-7	2001	11135578		A S Weinmann, D M Mitchell, S Sanjabi, M N Bradley, A Hoffmann, H C Liou, S T Smale	A S Weinmann	S T Smale	Howard Hughes Medical Institute and Department of Microbiology, Immunology and Molecular Genetics, UCLA, Los Angeles, CA 90095-1662, USA.	NIGMS NIH HHS; GM07185
Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST	Selective requirement for c-Rel during IL-12 P40 gene induction in macrophages.	Proc. Natl. Acad. Sci. U.S.A.	97:23:12705-10	2000	11058167		S Sanjabi, A Hoffmann, H C Liou, D Baltimore, S T Smale	S Sanjabi	S T Smale	Howard Hughes Medical Institute and Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, CA 90095-1662, USA.	NIAID NIH HHS; T32AI07323
Gardner TJ, Bolovan-Fritts C, Teng MW, Redmann V, Kraus TA, Sperling R, Moran T, Britt W, Weinberger LS, Tortorella D	Development of a high-throughput assay to measure the neutralization capability of anti-cytomegalovirus antibodies.	Clin. Vaccine Immunol.	20:4:540-50	2013	23389931		Thomas J Gardner, Cynthia Bolovan-Fritts, Melissa W Teng, Veronika Redmann, Thomas A Kraus, Rhoda Sperling, Thomas Moran, William Britt, Leor S Weinberger, Domenico Tortorella	Thomas J Gardner	Domenico Tortorella	Mount Sinai School of Medicine, Department of Microbiology, New York, NY, USA.	NIAID NIH HHS; T32-AI07647
Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Simpson ML, Shenk T, Weinberger LS	An endogenous accelerator for viral gene expression confers a fitness advantage.	Cell	151:7:1569-80	2012	23260143		Melissa W Teng, Cynthia Bolovan-Fritts, Roy D Dar, Andrew Womack, Michael L Simpson, Thomas Shenk, Leor S Weinberger	Melissa W Teng	Leor S Weinberger	The Gladstone Institutes, San Francisco, CA 94158, USA.	NCI NIH HHS; R01CA85786
Rouzine IM, Weinberger LS	Design requirements for interfering particles to maintain coadaptive stability with HIV-1.	J. Virol.	87:4:2081-93	2013	23221552		Igor M Rouzine, Leor S Weinberger	Igor M Rouzine	Leor S Weinberger	The Gladstone Institutes, San Francisco, California, USA.	NIGMS NIH HHS; P50 GM081879
Razooky BS, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger LS	Microwell devices with finger-like channels for long-term imaging of HIV-1 expression kinetics in primary human lymphocytes.	Lab Chip	12:21:4305-12	2012	22976503		Brandon S Razooky, Edgar Gutierrez, Valeri H Terry, Celsa A Spina, Alex Groisman, Leor S Weinberger	Brandon S Razooky	Leor S Weinberger	Department of Chemistry and Biochemistry, University of California, San Diego, CA 92023, USA.	NIAID NIH HHS; P01 AI090935
Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS	Transcriptional burst frequency and burst size are equally modulated across the human genome.	Proc. Natl. Acad. Sci. U.S.A.	109:43:17454-9	2012	23064634		Roy D Dar, Brandon S Razooky, Abhyudai Singh, Thomas V Trimeloni, James M McCollum, Chris D Cox, Michael L Simpson, Leor S Weinberger	Roy D Dar	Leor S Weinberger	Gladstone Institutes, San Francisco, CA 94158, USA.	NIGMS NIH HHS; P50GM081879
Singh A, Razooky BS, Dar RD, Weinberger LS	Dynamics of protein noise can distinguish between alternate sources of gene-expression variability.	Mol. Syst. Biol.	8:607	2012	22929617		Abhyudai Singh, Brandon S Razooky, Roy D Dar, Leor S Weinberger	Abhyudai Singh	Leor S Weinberger	Department of Chemistry and Biochemistry, University of California, San Diego, CA, USA.	NIGMS NIH HHS; P50 GM085764
Metzger VT, Lloyd-Smith JO, Weinberger LS	Autonomous targeting of infectious superspreaders using engineered transmissible therapies.	PLoS Comput. Biol.	7:3:e1002015	2011	21483468		Vincent T Metzger, James O Lloyd-Smith, Leor S Weinberger	Vincent T Metzger	Leor S Weinberger	Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, United States of America.	NA
Franz K, Singh A, Weinberger LS	Lentiviral vectors to study stochastic noise in gene expression.	Meth. Enzymol.	497:603-22	2011	21601105		Kate Franz, Abhyudai Singh, Leor S Weinberger	Kate Franz	Leor S Weinberger	Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, California, USA.	NIGMS NIH HHS; GM083395