This repository contains all protocols, models, codes, figure generating files, and animation for the comparison of ICaL models.
An interactive view of our main results can be viewed on the Cardiac Electrophysiology Web Lab.
- Example Models gives the equations for a Hodgkin-Huxley model and a Markov model.
- Models contains the CellML implementations for all models used (quantitatively) in this study, with links to the original sources and an overview of major data sources used in their construction.
- Figure 1
- Figure generating file is here.
- Figure 6
- Figure 7, Figure 8, Figure 9, and Figure 10
- Figure 11
- Figure 12
- Figure 13
- Figure generating file is here.
- Figure 14
- Figure 15 and Figure 16
- Figure 17 generated using the python script here.
- Web Lab Simulations were run using the Cardiac Electrophysiology Web Lab. An interactive overview of our results is available here. Find out more about Web Lab from doi: 10.1016/j.bpj.2015.12.012.
- Python The code requires Python (either 2.7 or 3.3+) and the Python dependencies Myokit, and
pandas. The other dependencies can be installed withpip, e.g.pip install myokit(orpip3 install myokitfor some python 3 environments). - CellML All model files are available in the CellML format. You can find out more about CellML from cellml.org.
- Veusz We have used this scientific plotting and graphing program to generate the figures for this work. This can be download from https://veusz.github.io/.
Please refer to the information in the CITATION file.