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Philip Reiner Kensche edited this page Nov 17, 2021 · 19 revisions

This plugins contains alignment and quality control related Roddy workflows:

  • PanCancer alignment workflow for
    • whole genome sequencing (WGS) and
    • whole exome sequencing (WES)
  • Whole genome bisulfite workflow (WGBS) using methylCtools. For tagmentation WGBS and PBAT a modified version is used (described here).

These workflows are basically BWA alignment (bwa mem) workflows with plenty of additional quality control steps.

QC-steps acting on the BAM files are mostly done through piping the input data into multiple QC tools simultaneously to minimize I/O and thus maximize throughput.

Change Logs

Please see the changelogs file for details.

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