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add parentage for anti-GBM disease #559

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tutajm opened this issue Aug 9, 2018 · 2 comments
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add parentage for anti-GBM disease #559

tutajm opened this issue Aug 9, 2018 · 2 comments
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@tutajm
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tutajm commented Aug 9, 2018

Let's start with: https://www.healthline.com/health/anti-glomerular-basement-membrane
https://unckidneycenter.org/kidneyhealthlibrary/glomerular-disease/anti-gbm-disease/
https://en.wikipedia.org/wiki/Goodpasture_syndrome

Goodpasture syndrome (DOID:9808)
anti-basement membrane glomerulonephritis (DOID:4780)

Facts: Anti-GBM disease that only affects the kidneys is called anti-GBM glomerulonephritis. Anti-GBM disease that causes both kidney disease and lung disease is called Goodpasture’s syndrome.

Therefore, for anti-basement membrane glomerulonephritis (DOID:4780):

  1. add parent is_a: DOID:417 ! autoimmune hypersensitivity disease

And for [Goodpasture’s syndrome]:

  1. add parent is-a DOID:4780,
  2. add parent is-a [interstitial lung disease (DOID:3082)]
  3. add parent [syndrome] DOID:225
  4. drop parent DOID:417 (redundant -- implied by DOID:4780 parentage)

It won't hurt to add some synonyms to these terms as well.

@lschriml
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Thank you !!
We will review.
Cheers,
Lynn

@lschriml lschriml self-assigned this Aug 27, 2018
@lschriml
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In DO, Goodpasture syndrome is_a asserted child of autoimmune hypersensitivity disease
synonyms of Goodpasture syndrome: anti-Glomerular Basement Membrane Disease
anti-GBM disease

Anti-GBM disease is the result of injury to small blood vessels (capillaries) in the kidney or lung.
Anti-GBM disease that causes both kidney disease and lung disease is called Goodpasture’s syndrome

Goodpasture syndrome (GPS), also known as anti-glomerular basement membrane disease, is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure.

   -- moving: (to be an asserted is_a child of Goodpasture syndrome)
             anti-basement membrane glomerulonephritis (DOID:4780)
                    Anti-GBM disease that only affects the kidneys is called anti-GBM glomerulonephritis

Axioms have been added for the lung and kidney, thus inferred parents.

Cheers,
Lynn

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