CYP3A4 Inducers

Strong: decrease the AUC by ≥80%

Moderate: decrease the AUC by ≥50 to <80%

Strong inducers

carbamazepine
antiandrogens
- enzalutamide
- apalutamide
phenytoin
rifampin

Weak inducers

upadacitinib

Inducers of unspecified potency

anticonvulsants
- oxcarbazepine
- topiramate
barbiturates
- phenobarbital
- butalbital
St. John's wort
bactericidals
- rifampicin
- rifabutin
antiretroviral drugs
- efavirenz
- nevirapine
troglitazone
glucocorticoids
modafinil
capsaicin
brigatinib
clobazam
dabrafenib
elagolix
eslicarbazepine
letermovir
lorlatinib
oritavancin
perampanel
telotristat