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Prediction scores from multiMiR output #30

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duz39 opened this issue Mar 1, 2019 · 1 comment
Open

Prediction scores from multiMiR output #30

duz39 opened this issue Mar 1, 2019 · 1 comment
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@duz39
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duz39 commented Mar 1, 2019

Sorry to post this again -- I left the same text in a comment, but I wasn't sure if I should post as a new issue. First, I would like to thank your group for making this tool publicly available. My issue is that I am not sure how to interpret the multiMiR output prediction scores: I recognize that each database calculates its own prediction score, but many of them calculate multiple scores and it is unclear which of these the multiMiR output includes. Further, I can't find information about the prediction score calculation for some of the databases (e.g. microcosm). It is difficult to filter by score without knowing what prediction scores signify or the suggested cutoff for the different databases. The information that is available in the Ru et al 2014 multiMiR publication also doesn't seem to align with the multiMiR output I produced in 2019 (i.e., for PITA, the publication discusses a prediction score of 0 to 1, but my prediction scores range from -7 to -22. I assume this is actually PITA's delta delta G score, but I'm not sure. Is this information available somewhere?

@smahaffey
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@duz39 I'm sorry for the delayed response. I don't think I will be able to get much more detail for databases that are no longer available, but I will try to summarize the values that were used for each database available.

@smahaffey smahaffey self-assigned this May 7, 2020
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