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EPNDCS1shacl.ttl
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EPNDCS1shacl.ttl
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@prefix OBI: <http://purl.obolibrary.org/obo>.
@prefix ncbi: <https://www.ncbi.nlm.nih.gov/gene/>.
@prefix LNC: <http://purl.bioontology.org/ontology/LNC>.
@prefix ex: <http://example/#> .
@prefix schema: <http://schema.org/> .
@prefix dash: <http://datashapes.org/dash#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sh: <http://www.w3.org/ns/shacl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/>.
@prefix snomed: <http://purl.bioontology.org/ontology/SNOMEDCT/>.
@prefix UO: <http://purl.obolibrary.org/obo/>.
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix sty: <http://purl.bioontology.org/ontology/STY/>.
@prefix loinc: <http://purl.bioontology.org/ontology/LNC/>.
@prefix EPND: <http://epnd.org/ontology/>.
sty:T081 rdfs:label "quantitative concept".
sty:T080 rdfs:label "qualitative concept".
sty:T079 rdfs:label "temporal concept".
OBI:0003076 rdfs:label "An age since birth at the time of a clinical visit.".
snomed:429019009 rdfs:label "Finding related to biological sex".
snomed:224288002 rdfs:label "Duration of formal education (observable entity)".
snomed:439272007 rdfs:label "Date of procedure (observable entity)".
snomed:459651000124107 rdfs:label "Montreal cognitive assessment score".
snomed:273617000 rdfs:label "Mini Mental State Examination".
snomed:273633002 rdfs:label "Motor assessment scale score".
ncbi:348 rdfs:label "APOE genotype category".
LNC:MTHU015751 rdfs:label "collection date ".
EPND:AgeAtSampleDate rdfs:label "Age when biosample was taken.".
EPND:ClinicalDiagnosis rdfs:label "Diagnosis of cognitive performance, function".
EPND:ClinicalDiagnosisDate rdfs:label "Date of clinical diagnosis".
EPND:ClinicalDementiaDiagnosis rdfs:label "type of dementia diagnosis".
EPND:ADDiseaseStaging rdfs:label "Staging according to a combination of amyloid pathology and cognitive impairment".
EPND:MemoryAssessment rdfs:label "Memory assessment".
EPND:MemoryRawScore rdfs:label "Raw score of Memory assessment".
EPND:MemoryLocalNorms rdfs:label "Local norms of memory assessment".
EPND:standerdisedZScore rdfs:label "Z-score of memory assessment".
EPND:APOE4Status rdfs:label "APOE 4 allele status".
EPND:GBAGenotypeStatus rdfs:label "GBA Genotype status".
EPND:CSFAmyloidBeta42Cutoff rdfs:label "CSF Amyloid-beta42 cut off dependent on the assay and for different pre-analytical procedures in the cohort. ".
EPND:AmyloidBeta42Status rdfs:label "Amyloid beta 42 status ".
EPND:AmyloidBeta42 rdfs:label "Amyloid beta 42".
snomed:248153007 rdfs:label "Male".
snomed:248152002 rdfs:label "Female".
snomed:32570691000036108 rdfs:label "Intersex".
EPND:NC rdfs:label "Normal cognition".
EPND:MCI rdfs:label "Mild cognitive impairment".
EPND:Dementia rdfs:label "dementia (mild-moderate-severe)".
EPND:ADDementia rdfs:label "Alzheimer disease dementia".
EPND:DLBDementia rdfs:label "Dementia with Lewy bodies ".
EPND:PDDementia rdfs:label "Parkinson's disease dementia".
EPND:PreclinicalAD rdfs:label "Combination of amyloid pathology and no cognitive impairment: Amyloid + NC/SCD".
EPND:ProdromalAD rdfs:label "Combination of amyloid pathology and and cognitive impairment: Amyloid + MCI".
EPND:ADDementia rdfs:label "Combination of amyloid pathology and dementia: Amyloid + dementia".
EPND:E2E2 rdfs:label "APOE allele E2E2".
EPND:E2E3 rdfs:label "APOE allele E2E3".
EPND:E2E4 rdfs:label "APOE allele E2E4".
EPND:E3E3 rdfs:label "APOE allele E3E3".
EPND:E3E4 rdfs:label "APOE allele E3E4".
EPND:E4E4 rdfs:label "APOE allele E4E4".
sio:SIO_000269 rdfs:label "true".
sio:SIO_000270 rdfs:label "false".
sio:SIO_000137 rdfs:label "category".
sio:SIO_000915 rdfs:label "numeric scale".
sio:SIO_000914 rdfs:label "binary scale".
sio:SIO_000221 rdfs:label "has unit".
sio:SIO_000300 rdfs:label "has value".
sio:SIO_000223 rdfs:label "has property".
ex:An_age_since_birth_measurement_datum_at_the_time_of_a_clinical_visit_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass OBI:0003076;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000033;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name OBI:0003076;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name OBI:0003076;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 130.0;
].
ex:Demographics_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:An_age_since_birth_measurement_datum_at_the_time_of_a_clinical_visit_Shape;
sh:minCount 1;
].
ex:Age_when_biosample_was_taken__Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:AgeAtSampleDate;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000033;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:AgeAtSampleDate;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:AgeAtSampleDate;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 130.0;
].
ex:Demographics_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Age_when_biosample_was_taken__Shape;
sh:minCount 1;
].
ex:Duration_of_formal_education_observable_entity_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass snomed:224288002;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:224288002;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:224288002;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 130.0;
].
ex:Demographics_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Duration_of_formal_education_observable_entity_Shape;
sh:minCount 1;
].
ex:Montreal_cognitive_assessment_score_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass snomed:459651000124107;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:459651000124107;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:459651000124107;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 31.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Montreal_cognitive_assessment_score_Shape;
sh:minCount 1;
].
ex:Mini_Mental_State_Examination_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass snomed:273617000;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:273617000;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:273617000;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 31.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Mini_Mental_State_Examination_Shape;
sh:minCount 1;
].
ex:Memory_assessment_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:MemoryAssessment ;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:MemoryAssessment ;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Memory_assessment_Shape;
sh:minCount 1;
].
ex:Raw_score_of_memory_assessment_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:MemoryRawScore;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:MemoryRawScore;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Raw_score_of_memory_assessment_Shape;
sh:minCount 1;
].
ex:Local_norms_of_memory_assessment_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:MemoryLocalNorms;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:None;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:MemoryLocalNorms;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Local_norms_of_memory_assessment_Shape;
sh:minCount 1;
].
ex:Zscore_of_memory_assessment_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:standerdisedZScore;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:None;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:standerdisedZScore;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Zscore_of_memory_assessment_Shape;
sh:minCount 1;
].
ex:Motor_assessment_scale_score_Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass snomed:273633002;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue UO:UO_0000189;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name snomed:273633002;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
].
ex:Motor_function_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Motor_assessment_scale_score_Shape;
sh:minCount 1;
].
ex:CSF_Amyloidbeta42_cut_off_dependent_on_the_assay_and_for_different_preanalytical_procedures_in_the_cohort__Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:CSFAmyloidBeta42Cutoff;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue snomed:258808001;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:CSFAmyloidBeta42Cutoff;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:CSFAmyloidBeta42Cutoff;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 5000.0;
].
ex:Local_CSF_measures_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:CSF_Amyloidbeta42_cut_off_dependent_on_the_assay_and_for_different_preanalytical_procedures_in_the_cohort__Shape;
sh:minCount 1;
].
ex:Amyloid_beta42__Shape a sh:NodeShape, sio:SIO_000915; #numeric
sh:targetClass EPND:AmyloidBeta42;
sh:closed true;
sh:property [
sh:path rdf:type;
sh:hasValue snomed:258808001;
sh:minCount 1;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:AmyloidBeta42;
sh:minCount 1;
sh:maxCount 1;
sh:minInclusive 0.0;
];
sh:property [
sh:path sio:SIO_000300; #has value
sh:datatype xsd:int;
sh:name EPND:AmyloidBeta42;
sh:minCount 1;
sh:maxCount 1;
sh:maxInclusive 5000.0;
].
ex:Local_CSF_measures_Shape a sh:NodeShape;
sh:targetClass sty:T081; #quantitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T081; #quantitative concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Amyloid_beta42__Shape;
sh:minCount 1;
].
ex:Date_of_clinical_diagnosis_Shape a sh:NodeShape, sio:SIO_000418; #time instant
sh:closed true;
sh:targetClass EPND:ClinicalDiagnosisDate;
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDiagnosisDate;
];
sh:property [
sh:path sio:SIO_000221; #has unit
sh:node ex:dateFormat;
].
ex:dateFormat a sh:NodeShape;
sh:targetClass schema:Date; #date in ISO 8601 date format
sh:closed true;
sh:property [
sh:path rdf:type ;
sh:hasValue schema:Date; #date in ISO 8601 date format
];
sh:property [
sh:path sio:SIO_000300; #has_value
sh:datatype xsd:date;
skos:altLabel 'date YYYY-MM-DD';
].
ex:Diagnosis_Shape a sh:NodeShape;
sh:targetClass sty:T079; #temporal concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T079; #temporal concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Date_of_clinical_diagnosis_Shape;
sh:minCount 1;
].
ex:Date_of_procedure_observable_entity_Shape a sh:NodeShape, sio:SIO_000418; #time instant
sh:closed true;
sh:targetClass snomed:439272007;
sh:property [
sh:path rdf:type;
sh:hasValue snomed:439272007;
];
sh:property [
sh:path sio:SIO_000221; #has unit
sh:node ex:dateFormat;
].
ex:dateFormat a sh:NodeShape;
sh:targetClass schema:Date; #date in ISO 8601 date format
sh:closed true;
sh:property [
sh:path rdf:type ;
sh:hasValue schema:Date; #date in ISO 8601 date format
];
sh:property [
sh:path sio:SIO_000300; #has_value
sh:datatype xsd:date;
skos:altLabel 'date YYYY-MM-DD';
].
ex:Cognition_Shape a sh:NodeShape;
sh:targetClass sty:T079; #temporal concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T079; #temporal concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:Date_of_procedure_observable_entity_Shape;
sh:minCount 1;
].
ex:collection_date__Shape a sh:NodeShape, sio:SIO_000418; #time instant
sh:closed true;
sh:targetClass LNC:MTHU015751;
sh:property [
sh:path rdf:type;
sh:hasValue LNC:MTHU015751;
];
sh:property [
sh:path sio:SIO_000221; #has unit
sh:node ex:dateFormat;
].
ex:dateFormat a sh:NodeShape;
sh:targetClass schema:Date; #date in ISO 8601 date format
sh:closed true;
sh:property [
sh:path rdf:type ;
sh:hasValue schema:Date; #date in ISO 8601 date format
];
sh:property [
sh:path sio:SIO_000300; #has_value
sh:datatype xsd:date;
skos:altLabel 'date YYYY-MM-DD';
].
ex:Sample_related_info_Shape a sh:NodeShape;
sh:targetClass sty:T079; #temporal concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T079; #temporal concept
];
sh:property [
sh:path sio:SIO_000011; #is attribute of
sh:node ex:collection_date__Shape;
sh:minCount 1;
].
ex:Finding_related_to_biological_sex_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass snomed:429019009;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue snomed:429019009;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue snomed:248153007;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue snomed:429019009;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue snomed:248152002;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue snomed:429019009;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue snomed:32570691000036108;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( snomed:248153007 snomed:248152002 snomed:32570691000036108 snomed:429019009 ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Demographics_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept
];
sh:property [
sh:path sio:SIO_000137; #is attribute of
sh:node ex:Finding_related_to_biological_sex_Shape;
sh:minCount 1;
].
ex:Diagnosis_of_cognitive_performance_function_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass EPND:ClinicalDiagnosis ;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDiagnosis ;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:NC;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDiagnosis ;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:MCI;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDiagnosis ;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:Dementia;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( EPND:NC EPND:MCI EPND:Dementia EPND:ClinicalDiagnosis ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Diagnosis_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept
];
sh:property [
sh:path sio:SIO_000137; #is attribute of
sh:node ex:Diagnosis_of_cognitive_performance_function_Shape;
sh:minCount 1;
].
ex:Type_of_dementia_diagnosis_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass EPND:ClinicalDementiaDiagnosis;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDementiaDiagnosis;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ADDementia;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDementiaDiagnosis;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:DLBDementia;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ClinicalDementiaDiagnosis;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:PDDementia;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( EPND:ADDementia EPND:DLBDementia EPND:PDDementia EPND:ClinicalDementiaDiagnosis ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Diagnosis_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept
];
sh:property [
sh:path sio:SIO_000137; #is attribute of
sh:node ex:Type_of_dementia_diagnosis_Shape;
sh:minCount 1;
].
ex:Staging_according_to_a_combination_of_amyloid_pathology_and_cognitive_impairment_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass EPND:ADDiseaseStaging;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ADDiseaseStaging;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:PreclinicalAD;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ADDiseaseStaging;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ProdromalAD;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ADDiseaseStaging;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:ADDementia;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( EPND:PreclinicalAD EPND:ProdromalAD EPND:ADDementia EPND:ADDiseaseStaging ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Diagnosis_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept
];
sh:property [
sh:path sio:SIO_000137; #is attribute of
sh:node ex:Staging_according_to_a_combination_of_amyloid_pathology_and_cognitive_impairment_Shape;
sh:minCount 1;
].
ex:APOE_4_allele_status_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass EPND:APOE4Status;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue EPND:APOE4Status;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue sio:SIO_000269;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue EPND:APOE4Status;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue sio:SIO_000270 ;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( sio:SIO_000269 sio:SIO_000270 EPND:APOE4Status ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Genetics_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept
];
sh:property [
sh:path sio:SIO_000137; #is attribute of
sh:node ex:APOE_4_allele_status_Shape;
sh:minCount 1;
].
ex:APOE_genotype_category_Shape a sh:NodeShape, sio:SIO_000137; #category
sh:closed true;
sh:targetClass ncbi:348;
sh:xone
(
[
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E2E2;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E2E3;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E2E4;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E3E3;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E3E4;
sh:minCount 2;
sh:maxCount 2;
];
] [
sh:property [
sh:path rdf:type;
sh:hasValue ncbi:348;
sh:minCount 2;
sh:maxCount 2;
];
sh:property [
sh:path rdf:type;
sh:hasValue EPND:E4E4;
sh:minCount 2;
sh:maxCount 2;
];
]
);
sh:property [
sh:path rdf:type ;
sh:in ( EPND:E2E2 EPND:E2E3 EPND:E2E4 EPND:E3E3 EPND:E3E4 EPND:E4E4 ncbi:348 ) ;
sh:minCount 2; # columnClass and valueClass combination
].
ex:Genetics_Shape a sh:NodeShape;
sh:targetClass sty:T080; #qualitative concept
sh:property [
sh:path rdf:type ;
sh:hasValue sty:T080; #qualitative concept