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readme.html
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readme.html
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<html><pre>
This is the readme for the model associated with the paper:
Lawrence JJ, Saraga F, Churchill JF, Statland JM, Travis KE, Skinner FK,
McBain CJ (2006) Somatodendritic Kv7-KCNQ-M channels control interspike
interval in hippocampal interneurons. J Neurosci 26:12325-38
Usage:
Auto-launch from ModelDB or download and extract the archive and then under
ms-win
------
Compile the mod files by running mknrndll and changing to the extracted
folder and selecting to create the nrnmech.dll. Then double click on
the mosinit.hoc file
linux/unix
----------
Compile the mod files by running nrnivmodl in the extracted folder. Then
run "nrngui mosinit.hoc"
mac os x
--------
Drag and drop the extracted folder onto the mknrndll icon. Drag and drop
the mosinit.hoc file from the extracted folder onto the nrngui icon.
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Once the simulation starts you can create subplots of Fig 9 by clicking
the appropriately labeled buttons or you can create the whole figure by
clicking the create all of fig 9 button (lower right in control box)
and you will get a figure like:
<img src="./screenshot.jpg" alt="screenshot">
Note: The variable step method was used in this demo, if you would like
to run the simulation as in the publication you can run cvode_active(0).
The model files were supplied by Dr Saraga.