/
tonic.ses
227 lines (224 loc) · 7.22 KB
/
tonic.ses
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/*
5/17/2017 Revised by N.T. Carnevale for the sake of conceptual clarity
and to facilitate attributed reuse.
In this version, the reference temperature is 23 deg C
and the value assigned to celsius is the actual operating temperature
in degrees celsius.
*/
objectvar save_window_, rvp_
objectvar scene_vector_[4]
objectvar ocbox_, ocbox_list_, scene_, scene_list_
{ocbox_list_ = new List() scene_list_ = new List()}
//Begin I/V Clamp Electrode
{
load_file("electrod.hoc")
}
{
ocbox_=new Electrode(0)
execute("can_locate=1 sec=\"soma\" xloc=0.55 locate(0)", ocbox_)
execute("vc.dur[0]=20 vc.amp[0]=-80", ocbox_)
execute("vc.dur[1]=200 vc.amp[1]=60", ocbox_)
execute("vc.dur[2]=10 vc.amp[2]=-80", ocbox_)
execute("stim.del=50 stim.dur=500 stim.amp=0.01", ocbox_)
execute("vcsteps=5", ocbox_)
execute("samp=stim.amp store_vclamp() glyph()", ocbox_)
ocbox_ = ocbox_.v1
ocbox_.map("I/V Clamp Electrode", 921, 13, 249.75, 459.75)
}
objref ocbox_
//End I/V Clamp Electrode
{
xpanel("NEURON Main Panel", 0)
xcheckbox("Quiet",&stdrun_quiet,"")
realtime = 6
xvalue("Real Time","realtime", 0,"", 0, 1 )
// celsius = 6.3
celsius = 23 // actual operating temperature
xvalue("celsius","celsius", 1,"", 0, 1 )
global_ra = 80
xvalue("Axial Resistivity","global_ra", 1,"set_ra()", 1, 1 )
xbutton("RunControl","nrncontrolmenu()")
xmenu("New Graph", 0)
xbutton("Voltage axis","newPlotV()")
xbutton("Current axis","newPlotI()")
xbutton("State axis","newPlotS()")
xbutton("Shape plot","newshapeplot()")
xbutton("Vector movie","newvectorplot()")
xbutton("Phase Plane","newphaseplane()")
xbutton("Grapher","load_proc(\"makegrapher\") makegrapher()")
xmenu()
xmenu("Point Processes", 0)
xmenu("Managers", 0)
xbutton("Point Manager","load_template(\"PointProcessManager\") makeppm()")
xbutton("Point Group","load_template(\"PointProcessGroupManager\") makeppgm()")
xbutton("Electrode","load_proc(\"makeelectrode\") makeelectrode()")
xmenu()
xmenu("Viewers", 0)
xmenu("PointProcesses", 0)
xbutton("IClamp","makePointBrowser(\"IClamp\")")
xbutton("AlphaSynapse","makePointBrowser(\"AlphaSynapse\")")
xbutton("SEClamp","makePointBrowser(\"SEClamp\")")
xbutton("VClamp","makePointBrowser(\"VClamp\")")
xbutton("APCount","makePointBrowser(\"APCount\")")
xmenu()
xmenu()
xmenu()
xmenu("Distributed Mechanisms", 0)
xmenu("Managers", 0)
xbutton("Inserter","load_template(\"Inserter\") makeinserter()")
xbutton("Homogeneous Spec","load_proc(\"makeshowmechanism\") makeshowmechanism()")
xmenu()
xmenu("Viewers", 0)
xbutton("Shape Name","load_template(\"MenuExplore\") makeMenuExplore()")
xbutton("Name Values","nrnallsectionmenu()")
xmenu("Mechanisms (Globals)", 0)
xbutton("na_ion","nrnglobalmechmenu(\"na_ion\")")
xbutton("k_ion","nrnglobalmechmenu(\"k_ion\")")
xbutton("hh","nrnglobalmechmenu(\"hh\")")
xmenu()
xmenu()
xmenu()
xmenu("Miscellaneous", 0)
xmenu("Clipboard", 0)
xbutton("Save to File","load_proc(\"clipboard_save\") clipboard_save()")
xbutton("Retrieve from File","load_proc(\"clipboard_retrieve\") clipboard_retrieve()")
xmenu()
xbutton("Family","load_template(\"Family\") makeFamily()")
xbutton("Parameterized Function","load_template(\"FunctionFitter\") makefitter()")
xbutton("Run Fitter","load_template(\"RunFitter\") makerunfitter()")
xmenu("Impedance", 0)
xbutton("Frequency","load_template(\"ImpedanceRatio\") makeImpRatio()")
xbutton("Path","load_template(\"Impx\") makeImpx()")
xbutton("log(A) vs x","load_template(\"LogAvsX\") makelogax()")
xbutton("Shape","load_template(\"ImpShape\") makeImpShape()")
xmenu()
xmenu()
xpanel(3,318)
}
{
xpanel("RunControl", 0)
v_init = -70
xvalue("Init","v_init", 1,"stdinit()", 1, 1 )
xbutton("Init & Run","run()")
xbutton("Stop","stoprun=1")
runStopAt = 5
xvalue("Continue til","runStopAt", 1,"{continuerun(runStopAt) stoprun=1}", 1, 1 )
runStopIn = 1
xvalue("Continue for","runStopIn", 1,"{continuerun(t + runStopIn) stoprun=1}", 1, 1 )
xbutton("Single Step","steprun()")
t = 700
xvalue("t","t", 2 )
tstop = 700
xvalue("Tstop","tstop", 1,"tstop_changed()", 0, 1 )
dt = 0.05
xvalue("dt","dt", 1,"setdt()", 0, 1 )
steps_per_ms = 20
xvalue("Points plotted/ms","steps_per_ms", 1,"setdt()", 0, 1 )
xpanel(601,16)
}
{
save_window_ = new Graph(0)
save_window_.size(0,700,-90,50)
scene_vector_[3] = save_window_
{save_window_.view(0, -90, 700, 140, 158, 10, 318.75, 265)}
graphList[0].append(save_window_)
save_window_.save_name("graphList[0].")
save_window_.addexpr("soma.v(0.5)", 1, 1, 0.46369, 0.933666, 2)
}
{
xpanel("soma(0 - 1) (Parameters)", 0)
xlabel("soma(0 - 1) (Parameters)")
xlabel("nseg = 10")
soma.L = 10
xvalue("L","soma.L", 1,"define_shape()", 0, 0 )
soma.cm = 1
xvalue("cm","soma.cm", 1,"", 0, 0 )
soma.diam = 10
xvalue("diam","soma.diam", 1,"", 0, 0 )
soma.gnabar_B_Na = 0.008
xvalue("gnabar_B_Na","soma.gnabar_B_Na", 1,"", 0, 0 )
soma.ena = 60
xvalue("ena","soma.ena", 1,"", 0, 0 )
soma.g_pas = 1.1e-05
xvalue("g_pas","soma.g_pas", 1,"", 0, 0 )
soma.e_pas = -70
xvalue("e_pas","soma.e_pas", 1,"", 0, 0 )
soma.gkbar_KDRI = 0.0043
xvalue("gkbar_KDRI","soma.gkbar_KDRI", 1,"", 0, 0 )
soma.ek = -84
xvalue("ek","soma.ek", 1,"", 0, 0 )
xpanel(303,567)
}
{
xpanel("dend[0](0 - 1) (Parameters)", 0)
xlabel("dend[0](0 - 1) (Parameters)")
xlabel("nseg = 50")
dend[0].L = 1371
xvalue("L","dend[0].L", 1,"define_shape()", 0, 0 )
dend[0].cm = 1
xvalue("cm","dend[0].cm", 1,"", 0, 0 )
dend[0].diam = 1.4
xvalue("diam","dend[0].diam", 1,"", 0, 0 )
dend[0].gnabar_SS = 0
xvalue("gnabar_SS","dend[0].gnabar_SS", 1,"", 0, 0 )
dend[0].ena = 60
xvalue("ena","dend[0].ena", 1,"", 0, 0 )
dend[0].g_pas = 1.1e-05
xvalue("g_pas","dend[0].g_pas", 1,"", 0, 0 )
dend[0].e_pas = -70
xvalue("e_pas","dend[0].e_pas", 1,"", 0, 0 )
dend[0].gkbar_KDRI = 0.034
xvalue("gkbar_KDRI","dend[0].gkbar_KDRI", 1,"", 0, 0 )
dend[0].ek = -84
xvalue("ek","dend[0].ek", 1,"", 0, 0 )
xpanel(9,562)
}
{
xpanel("hillock(0 - 1) (Parameters)", 0)
xlabel("hillock(0 - 1) (Parameters)")
xlabel("nseg = 30")
hillock.L = 30
xvalue("L","hillock.L", 1,"define_shape()", 0, 0 )
hillock.cm = 1
xvalue("cm","hillock.cm", 1,"", 0, 0 )
xlabel("diam is not constant")
hillock.gnabar_B_Na = 1.8
xvalue("gnabar_B_Na","hillock.gnabar_B_Na", 1,"", 0, 0 )
hillock.ena = 60
xvalue("ena","hillock.ena", 1,"", 0, 0 )
hillock.g_pas = 1.1e-05
xvalue("g_pas","hillock.g_pas", 1,"", 0, 0 )
hillock.e_pas = -70
xvalue("e_pas","hillock.e_pas", 1,"", 0, 0 )
hillock.gkbar_KDRI = 0.076
xvalue("gkbar_KDRI","hillock.gkbar_KDRI", 1,"", 0, 0 )
hillock.ek = -84
xvalue("ek","hillock.ek", 1,"", 0, 0 )
xpanel(628,567)
}
{
xpanel("axon(0 - 1) (Parameters)", 0)
xlabel("axon(0 - 1) (Parameters)")
xlabel("nseg = 50")
axon.L = 0.001
xvalue("L","axon.L", 1,"define_shape()", 0, 0 )
axon.cm = 1
xvalue("cm","axon.cm", 1,"", 0, 0 )
axon.diam = 0.001
xvalue("diam","axon.diam", 1,"", 0, 0 )
axon.gnabar_B_Na = 0
xvalue("gnabar_B_Na","axon.gnabar_B_Na", 1,"", 0, 0 )
axon.ena = 60
xvalue("ena","axon.ena", 1,"", 0, 0 )
axon.g_pas = 0
xvalue("g_pas","axon.g_pas", 1,"", 0, 0 )
axon.e_pas = -70
xvalue("e_pas","axon.e_pas", 1,"", 0, 0 )
axon.gkbar_KDRI = 0
xvalue("gkbar_KDRI","axon.gkbar_KDRI", 1,"", 0, 0 )
axon.ek = -84
xvalue("ek","axon.ek", 1,"", 0, 0 )
xpanel(949,566)
}
objectvar scene_vector_[1]
{doNotify()}