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nPhase has no option to set max heterozygosity level #10

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OmarOakheart opened this issue Oct 2, 2021 · 0 comments
Open

nPhase has no option to set max heterozygosity level #10

OmarOakheart opened this issue Oct 2, 2021 · 0 comments

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@OmarOakheart
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Whenever someone wants to run nPhase on a very heterozygous, large genome and runs into memory issues/takes too long to run, I recommend subsampling the vcf down to a 0.5~1% heterozygosity level since nPhase will still perform well (and significantly faster). This is probably a pain for everyone and it would be good to include an option to set a maximum heterozygosity level so that the pipeline can do the subsampling it on its own.

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