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parameters.json
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parameters.json
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{
"max_age": 100,
"mean_duration_polyp1_polyp2": 25.5,
"mean_duration_polyp2_polyp3": 6.25,
"mean_duration_polyp2_pre": 80,
"mean_duration_polyp3_pre": 76,
"mean_duration_pre1_pre2": 3.5,
"mean_duration_pre2_pre3": 2.5,
"mean_duration_pre3_pre4": 2.5,
"mean_duration_pre1_clin1": 18,
"mean_duration_pre2_clin2": 3.9,
"mean_duration_pre3_clin3": 2.75,
"mean_duration_pre4_clin4": 1.9,
"mean_duration_clin1_dead": 135,
"mean_duration_clin2_dead": 51,
"mean_duration_clin3_dead": 19,
"mean_duration_clin4_dead": 2.7,
"proportion_survive_clin1": 0,
"proportion_survive_clin2": 0,
"proportion_survive_clin3": 0,
"proportion_survive_clin4": 0,
"cost_polypectomy": 170,
"cost_polyp_pathology": 65,
"cost_treatment_stage1_initial": 34258,
"cost_treatment_stage1_ongoing": 2685,
"cost_treatment_stage1_terminal": 68339,
"cost_treatment_stage2_initial": 47790,
"cost_treatment_stage2_ongoing": 3266,
"cost_treatment_stage2_terminal": 77098,
"cost_treatment_stage3_initial": 71594,
"cost_treatment_stage3_ongoing": 5258,
"cost_treatment_stage3_terminal": 79770,
"cost_treatment_stage4_initial": 110161,
"cost_treatment_stage4_ongoing": 26474,
"cost_treatment_stage4_terminal": 99255,
"max_ongoing_treatments": 4,
"value_loss_cancer": 0.15,
"value_life_year_ages": [ 0, 65, 100],
"value_life_year_dollars": [217000, 547000, 547000],
"duration_screen_skip_testing": 5,
"surveillance_freq_polyp_none": 10,
"surveillance_freq_polyp_mild": 7,
"surveillance_freq_polyp_moderate": 3,
"surveillance_freq_polyp_severe": 1,
"surveillance_freq_cancer_first": 1,
"surveillance_freq_cancer_second": 3,
"surveillance_freq_cancer_rest": 5,
"surveillance_end_age": 85,
"use_conditional_compliance": true,
"initial_compliance_rate": 1.0,
"never_compliant_rate": 0.0,
"diagnostic_compliance_rate": 1.0,
"surveillance_compliance_rate": 1.0,
"lesion_risk_alpha": 0.47,
"lesion_risk_beta": 2.45,
"lesion_incidence_ages": [ 0, 20, 30, 40, 45, 50, 55, 60, 65, 70, 75, 85, 100 ],
"lesion_incidence_rates": [ 0.000, 0.002, 0.002, 0.015, 0.020, 0.025, 0.027, 0.027, 0.027, 0.014, 0.011, 0.011, 0.011 ],
"tests": {
"FIT": {
"proportion": 1.0,
"routine_start": 50,
"routine_end": 75,
"routine_freq": 1,
"specificity": 0.97,
"sensitivity_polyp1": 0.07,
"sensitivity_polyp2": 0.07,
"sensitivity_polyp3": 0.22,
"sensitivity_cancer": 0.74,
"cost": 22,
"proportion_perforation": 0,
"cost_perforation": 0,
"compliance_rate_given_prev_compliant": [ 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0 ],
"compliance_rate_given_not_prev_compliant": [ 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0 ]
},
"Colonoscopy": {
"proportion": 0.0,
"routine_start": 50,
"routine_end": 75,
"routine_freq": 10,
"specificity": 0.86,
"sensitivity_polyp1": 0.75,
"sensitivity_polyp2": 0.85,
"sensitivity_polyp3": 0.95,
"sensitivity_cancer": 0.95,
"cost": 700,
"proportion_perforation": 0.001,
"cost_perforation": 6487,
"compliance_rate_given_prev_compliant": [ 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0, 1.0 ],
"compliance_rate_given_not_prev_compliant": [ 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0, 0.0 ]
}
},
"routine_tests": [ "FIT", "Colonoscopy" ],
"diagnostic_test": "Colonoscopy",
"surveillance_test": "Colonoscopy",
"polypectomy_proportion_lethal": 0.00002,
"use_variable_routine_test": true,
"routine_testing_year": [ 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75 ],
"routine_test_by_year": ["Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "Colonoscopy", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT", "FIT" ],
"cost_discount_age": 50,
"cost_discount_rate": 0.03,
"lifespan_discount_age": 50,
"lifespan_discount_rate": 0.03,
"death_rate_black_female_ages": [ 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100 ],
"death_rate_black_female_rates": [ 0.009674, 0.000588, 0.000355, 0.000214, 0.000248, 0.000197, 0.000171, 0.000151, 0.000139, 0.000133, 0.000133, 0.000140, 0.000154, 0.000174, 0.000201, 0.000231, 0.000267, 0.000313, 0.000372, 0.000438, 0.000508, 0.000576, 0.000637, 0.000688, 0.000731, 0.000772, 0.000815, 0.000859, 0.000908, 0.000965, 0.001030, 0.001105, 0.001186, 0.001269, 0.001353, 0.001440, 0.001536, 0.001637, 0.001750, 0.001880, 0.002033, 0.002206, 0.002383, 0.002553, 0.002721, 0.002895, 0.003099, 0.003347, 0.003655, 0.004018, 0.004400, 0.004802, 0.005266, 0.005797, 0.006375, 0.006974, 0.007576, 0.008184, 0.008803, 0.009446, 0.010126, 0.010845, 0.011602, 0.012397, 0.013231, 0.014149, 0.015137, 0.016142, 0.017121, 0.018187, 0.019264, 0.020677, 0.022638, 0.024656, 0.026985, 0.029625, 0.032101, 0.035679, 0.039136, 0.042432, 0.047008, 0.051308, 0.055972, 0.061447, 0.067875, 0.073825, 0.081779, 0.090536, 0.100072, 0.110418, 0.121605, 0.133654, 0.146574, 0.160368, 0.175024, 0.190515, 0.206800, 0.223822, 0.241511, 0.259776, 1.000000 ],
"death_rate_black_male_ages": [ 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100 ],
"death_rate_black_male_rates": [ 0.011882, 0.000622, 0.000406, 0.000347, 0.000231, 0.000231, 0.000211, 0.000192, 0.000169, 0.000142, 0.000125, 0.000140, 0.000211, 0.000352, 0.000546, 0.000757, 0.000965, 0.001172, 0.001370, 0.001554, 0.001736, 0.001909, 0.002051, 0.002154, 0.002225, 0.002287, 0.002346, 0.002397, 0.002444, 0.002494, 0.002543, 0.002598, 0.002675, 0.002779, 0.002899, 0.003034, 0.003172, 0.003292, 0.003391, 0.003483, 0.003593, 0.003742, 0.003932, 0.004165, 0.004434, 0.004731, 0.005061, 0.005438, 0.005874, 0.006376, 0.006905, 0.007485, 0.008192, 0.009050, 0.010020, 0.011026, 0.012041, 0.013122, 0.014298, 0.015581, 0.016979, 0.018443, 0.019920, 0.021354, 0.022760, 0.024279, 0.025931, 0.027551, 0.029041, 0.030501, 0.031843, 0.034142, 0.036113, 0.039043, 0.041873, 0.044907, 0.048772, 0.052158, 0.057218, 0.062038, 0.066654, 0.072113, 0.079691, 0.087605, 0.094030, 0.100906, 0.110227, 0.120226, 0.130918, 0.142314, 0.154416, 0.167219, 0.180709, 0.194863, 0.209647, 0.225017, 0.240921, 0.257294, 0.274063, 0.291147, 1.000000 ],
"death_rate_white_female_ages": [ 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100 ],
"death_rate_white_female_rates": [ 0.004376, 0.000296, 0.000180, 0.000151, 0.000116, 0.000112, 0.000102, 0.000095, 0.000089, 0.000085, 0.000085, 0.000090, 0.000106, 0.000134, 0.000170, 0.000212, 0.000255, 0.000298, 0.000339, 0.000379, 0.000420, 0.000464, 0.000504, 0.000542, 0.000576, 0.000609, 0.000643, 0.000682, 0.000728, 0.000781, 0.000839, 0.000898, 0.000953, 0.001000, 0.001043, 0.001089, 0.001143, 0.001197, 0.001252, 0.001313, 0.001388, 0.001480, 0.001589, 0.001709, 0.001840, 0.001979, 0.002133, 0.002311, 0.002520, 0.002762, 0.003018, 0.003292, 0.003600, 0.003941, 0.004301, 0.004674, 0.005050, 0.005425, 0.005806, 0.006206, 0.006644, 0.007124, 0.007647, 0.008217, 0.008842, 0.009515, 0.010293, 0.011188, 0.012280, 0.013537, 0.014827, 0.016570, 0.018235, 0.020046, 0.021938, 0.024382, 0.027026, 0.029965, 0.033566, 0.037224, 0.041748, 0.046426, 0.052066, 0.059213, 0.066359, 0.073798, 0.081793, 0.092586, 0.104549, 0.117741, 0.132206, 0.147969, 0.165031, 0.183365, 0.202911, 0.223578, 0.245236, 0.267725, 0.290853, 0.314404, 1.000000 ],
"death_rate_white_male_ages": [ 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100 ],
"death_rate_white_male_rates": [ 0.005273, 0.000389, 0.000273, 0.000199, 0.000147, 0.000143, 0.000126, 0.000112, 0.000100, 0.000091, 0.000090, 0.000105, 0.000145, 0.000215, 0.000309, 0.000412, 0.000520, 0.000642, 0.000778, 0.000921, 0.001068, 0.001209, 0.001330, 0.001424, 0.001497, 0.001561, 0.001624, 0.001682, 0.001737, 0.001792, 0.001847, 0.001900, 0.001952, 0.002003, 0.002053, 0.002111, 0.002174, 0.002233, 0.002285, 0.002340, 0.002413, 0.002516, 0.002649, 0.002811, 0.002999, 0.003203, 0.003433, 0.003709, 0.004047, 0.004445, 0.004874, 0.005331, 0.005844, 0.006408, 0.007003, 0.007607, 0.008219, 0.008857, 0.009542, 0.010285, 0.011098, 0.011952, 0.012814, 0.013657, 0.014502, 0.015384, 0.016444, 0.017624, 0.018968, 0.020586, 0.022109, 0.024359, 0.026347, 0.028810, 0.031309, 0.034486, 0.038026, 0.042286, 0.046547, 0.051534, 0.057008, 0.062923, 0.069911, 0.078099, 0.086754, 0.096549, 0.106472, 0.119677, 0.134128, 0.149846, 0.166829, 0.185047, 0.204441, 0.224919, 0.246354, 0.268590, 0.291442, 0.314700, 0.338142, 0.361537, 1.000000 ],
"us_age_distribution_rates": [ 0.01237, 0.01236, 0.01234, 0.01231, 0.01208, 0.01214, 0.01213, 0.01209, 0.01211, 0.01225, 0.01225, 0.01225, 0.01264, 0.01270, 0.01260, 0.01257, 0.01262, 0.01257, 0.01257, 0.01293, 0.01318, 0.01304, 0.01310, 0.01319, 0.01332, 0.01362, 0.01389, 0.01409, 0.01443, 0.01466, 0.01460, 0.01401, 0.01366, 0.01340, 0.01342, 0.01348, 0.01304, 0.01320, 0.01317, 0.01301, 0.01323, 0.01241, 0.01214, 0.01200, 0.01164, 0.01197, 0.01159, 0.01174, 0.01224, 0.01290, 0.01303, 0.01232, 0.01204, 0.01203, 0.01223, 0.01294, 0.01315, 0.01311, 0.01306, 0.01319, 0.01326, 0.01278, 0.01266, 0.01248, 0.01198, 0.01183, 0.01129, 0.01081, 0.01033, 0.00995, 0.00965, 0.00930, 0.00912, 0.00941, 0.00689, 0.00671, 0.00645, 0.00649, 0.00557, 0.00499, 0.00462, 0.00424, 0.00395, 0.00352, 0.00324, 0.00298, 0.00255, 0.00234, 0.00211, 0.00188, 0.00168, 0.00140, 0.00120, 0.00099, 0.00079, 0.00064, 0.00049, 0.00036, 0.00027, 0.00019, 0.00028 ]
}