The :g command can be used to execute an Ex command over the entire buffer
for all lines that match a given pattern. By choosing d (delete) as the Ex
command, all lines that match the given pattern will be deleted. For
instance, if I want to remove all lines that contain binding.pry, I can
execute the following command:
:g/binding\.pry/d
See :h :g for more details.
h/t Chris Erin