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Flux comparison using GLPK & CPLEX #332
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It might be good to double-check which reactions have those very low fluxes. But it indeed seems to be an artifact of the solver and not the true difference of the flux distributions. I can modify In the Materials section is mentioned that Gurobi is strongly recommended. |
Please review #331 to see if the plots look more similar. |
It now looks similar using GLPK. But using CPLEX via COBRA got the error:
I am not sure if this should be fixed as CPLEX is not mentioned in the Materials section. But this means that there must be some bug in the code. |
I imagine this would happen if CPLEX failed to find a solution ( |
I used GLPK and CPLEX (via COBRA) to run Step 29 but got quite different plots (see attached plots.zip). The deviation comes from the comparison between extremely low fluxes. While the plots look different, the general conclusion still holds: the simulated objective fluxes are the same, and there is no big difference between mapped fluxes simulated by light and full ecModels.
I have an issue with the license of GUROBI currently and thus do not have the corresponding result for comparison. But I suppose that the plot in the manuscript was generated using GUROBI, which looks much better than the other two solvers. Maybe we could mention in the manuscript that all the anticipated results are obtained with GUROBI (I also got a slightly different FVA plot using GLPK). And maybe only plot high absolute fluxes (e.g. > 1e-6) as the extremely low fluxes make no sense.
Below I also put what I got in the Command Window using these two solvers:
GLPK:
CPLEX:
I hereby confirm that I have:
feat/compareLightVsFull
branch of the repositoryThe text was updated successfully, but these errors were encountered: