LipidLynxX can't be finished.

[zebrafish-507]

When I run LipidLynxX both on the web and in a local, the page is always "LipidLynxX is running", the the program can't be completed. Even the example lipid names were submitted.

[Stemanz]

May 23rd, 2024. Still not working, the conversion takes forever even with only one lipid.

[ZhixuNi]

Dear @zebrafish-507 and @Stemanz ,

I understand that some of the tasks can not be finished and you probably think the tool has many issues.

When I check our tool with some of our data, normally it is working fine.

There are few known issues for Ceramides and sphingolipids that the names are not converted correctly.

This is a known issue and we are developing the version 2 for quite some time for that.

However, there are many issues not from us.

LipidLynxX is designed for lipid names only, so if there are some names from non-lipid metabolites or proteins, the program will crash. Normally a lipidomics identification list is not longer than 1500 lipids. We faced the users uploading 3k or more names with mix of many non-lipid metabolites and the lipidlynxx on LIPIDMAPS had to be offline for maintenance.

Please, if it is not sensitive data, send us your lipid name list so we can have a look and check why the program is not running for you. You can also send me the links for GoogleDrive or OneDrive as well.

Many thanks for the feedback.
Lipid name conversion is a complicated work and we need to work together to bring a better solution.

Best,
Ni