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<g id="node4" class="node"><title>DN_4</title>
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<g id="edge3" class="edge"><title>DAN_1&#45;&gt;DN_4</title>
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<!-- MN_2&#45;&gt;DAN_1 -->
<g id="edge1" class="edge"><title>MN_2&#45;&gt;DAN_1</title>
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<!-- MN_2&#45;&gt;M_3 -->
<g id="edge2" class="edge"><title>MN_2&#45;&gt;M_3</title>
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<!-- DN_4&#45;&gt;D_5 -->
<g id="edge4" class="edge"><title>DN_4&#45;&gt;D_5</title>
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<!-- MN_6&#45;&gt;MN_9 -->
<g id="edge7" class="edge"><title>MN_6&#45;&gt;MN_9</title>
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<!-- MN_7&#45;&gt;MN_6 -->
<g id="edge5" class="edge"><title>MN_7&#45;&gt;MN_6</title>
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<!-- MN_7&#45;&gt;M_8 -->
<g id="edge6" class="edge"><title>MN_7&#45;&gt;M_8</title>
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<!-- MN_7&#45;&gt;MN_11 -->
<g id="edge9" class="edge"><title>MN_7&#45;&gt;MN_11</title>
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<g id="edge8" class="edge"><title>MN_9&#45;&gt;M_10</title>
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<g id="edge41" class="edge"><title>MN_9&#45;&gt;DAN_45</title>
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<text text-anchor="middle" x="3230" y="-549.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.1:out:0</text>
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<!-- MN_11&#45;&gt;MN_12 -->
<g id="edge10" class="edge"><title>MN_11&#45;&gt;MN_12</title>
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<!-- MN_12&#45;&gt;M_13 -->
<g id="edge11" class="edge"><title>MN_12&#45;&gt;M_13</title>
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<text text-anchor="middle" x="3920" y="-549.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.1</text>
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<!-- MN_12&#45;&gt;DAN_27 -->
<g id="edge23" class="edge"><title>MN_12&#45;&gt;DAN_27</title>
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<!-- DN_17 -->
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<text text-anchor="middle" x="4722" y="-299.3" font-family="Times New Roman,serif" font-size="14.00">DN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.3:out:0</text>
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<g id="edge14" class="edge"><title>DAN_14&#45;&gt;DN_17</title>
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<!-- MN_15 -->
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<text text-anchor="middle" x="3230" y="-299.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.3:out:0</text>
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<!-- MN_15&#45;&gt;DAN_14 -->
<g id="edge12" class="edge"><title>MN_15&#45;&gt;DAN_14</title>
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<!-- MN_15&#45;&gt;M_16 -->
<g id="edge13" class="edge"><title>MN_15&#45;&gt;M_16</title>
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<!-- DN_17&#45;&gt;D_18 -->
<g id="edge15" class="edge"><title>DN_17&#45;&gt;D_18</title>
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<!-- MN_19 -->
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<!-- MN_22 -->
<g id="node22" class="node"><title>MN_22</title>
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<text text-anchor="middle" x="3230" y="-424.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.2:out:0</text>
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<!-- MN_19&#45;&gt;MN_22 -->
<g id="edge18" class="edge"><title>MN_19&#45;&gt;MN_22</title>
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<!-- MN_20 -->
<g id="node20" class="node"><title>MN_20</title>
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<text text-anchor="middle" x="1769" y="-424.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.1:out:0</text>
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<!-- MN_20&#45;&gt;MN_19 -->
<g id="edge16" class="edge"><title>MN_20&#45;&gt;MN_19</title>
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<!-- MN_20&#45;&gt;M_21 -->
<g id="edge17" class="edge"><title>MN_20&#45;&gt;M_21</title>
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<g id="edge26" class="edge"><title>MN_20&#45;&gt;MN_30</title>
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<text text-anchor="middle" x="3230" y="-478.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay:a_ROS_experiment1.exp1&#45;A1&#45;C2&#45;Ch1</text>
</g>
<!-- MN_22&#45;&gt;M_23 -->
<g id="edge19" class="edge"><title>MN_22&#45;&gt;M_23</title>
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<polygon fill="black" stroke="black" points="3226.5,-453.79 3230,-463.79 3233.5,-453.79 3226.5,-453.79"/>
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<!-- DAN_24 -->
<g id="node24" class="node"><title>DAN_24</title>
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<text text-anchor="middle" x="3920" y="-424.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.2</text>
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<!-- MN_22&#45;&gt;DAN_24 -->
<g id="edge20" class="edge"><title>MN_22&#45;&gt;DAN_24</title>
<path fill="none" stroke="black" d="M3474.05,-428C3549.3,-428 3631.63,-428 3704.78,-428"/>
<polygon fill="black" stroke="black" points="3705.04,-431.5 3715.04,-428 3705.04,-424.5 3705.04,-431.5"/>
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<!-- DN_25 -->
<g id="node25" class="node"><title>DN_25</title>
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<text text-anchor="middle" x="4722" y="-424.3" font-family="Times New Roman,serif" font-size="14.00">DN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.2:out:0</text>
</g>
<!-- DAN_24&#45;&gt;DN_25 -->
<g id="edge21" class="edge"><title>DAN_24&#45;&gt;DN_25</title>
<path fill="none" stroke="black" d="M4329.5,-428C4377.19,-428 4424.73,-428 4469.39,-428"/>
<polygon fill="black" stroke="black" points="4469.47,-431.5 4479.47,-428 4469.47,-424.5 4469.47,-431.5"/>
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<!-- D_26 -->
<g id="node26" class="node"><title>D_26</title>
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<text text-anchor="middle" x="4722" y="-478.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay_derived_data:a_ROS_experiment1.data_ROS_experiment1_Ch1.txt (exp1&#45;A1&#45;C2&#45;Ch1)</text>
</g>
<!-- DN_25&#45;&gt;D_26 -->
<g id="edge22" class="edge"><title>DN_25&#45;&gt;D_26</title>
<path fill="none" stroke="black" d="M4722,-446.141C4722,-448.623 4722,-451.105 4722,-453.587"/>
<polygon fill="black" stroke="black" points="4718.5,-453.79 4722,-463.79 4725.5,-453.79 4718.5,-453.79"/>
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<!-- DN_28 -->
<g id="node28" class="node"><title>DN_28</title>
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<text text-anchor="middle" x="4722" y="-549.3" font-family="Times New Roman,serif" font-size="14.00">DN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.1:out:0</text>
</g>
<!-- DAN_27&#45;&gt;DN_28 -->
<g id="edge24" class="edge"><title>DAN_27&#45;&gt;DN_28</title>
<path fill="none" stroke="black" d="M4329.5,-553C4377.19,-553 4424.73,-553 4469.39,-553"/>
<polygon fill="black" stroke="black" points="4469.47,-556.5 4479.47,-553 4469.47,-549.5 4469.47,-556.5"/>
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<!-- D_29 -->
<g id="node29" class="node"><title>D_29</title>
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<text text-anchor="middle" x="4722" y="-603.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay_derived_data:a_ROS_experiment1.data_ROS_experiment1_Ch2.txt (exp1&#45;A1&#45;C1&#45;Ch2)</text>
</g>
<!-- DN_28&#45;&gt;D_29 -->
<g id="edge25" class="edge"><title>DN_28&#45;&gt;D_29</title>
<path fill="none" stroke="black" d="M4722,-571.141C4722,-573.623 4722,-576.105 4722,-578.587"/>
<polygon fill="black" stroke="black" points="4718.5,-578.79 4722,-588.79 4725.5,-578.79 4718.5,-578.79"/>
</g>
<!-- MN_30&#45;&gt;MN_15 -->
<g id="edge27" class="edge"><title>MN_30&#45;&gt;MN_15</title>
<path fill="none" stroke="black" d="M2949.6,-303C2958.42,-303 2967.18,-303 2975.84,-303"/>
<polygon fill="black" stroke="black" points="2975.97,-306.5 2985.97,-303 2975.97,-299.5 2975.97,-306.5"/>
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<!-- MN_31 -->
<g id="node31" class="node"><title>MN_31</title>
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<text text-anchor="middle" x="1014" y="-556.8" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.0</text>
<text text-anchor="middle" x="1014" y="-541.8" font-family="Times New Roman,serif" font-size="14.00">cell growth</text>
</g>
<!-- MN_31&#45;&gt;MN_7 -->
<g id="edge30" class="edge"><title>MN_31&#45;&gt;MN_7</title>
<path fill="none" stroke="black" d="M1479.29,-553C1488.21,-553 1497.05,-553 1505.8,-553"/>
<polygon fill="black" stroke="black" points="1506.03,-556.5 1516.03,-553 1506.03,-549.5 1506.03,-556.5"/>
</g>
<!-- MN_32 -->
<g id="node32" class="node"><title>MN_32</title>
<ellipse fill="ivory" stroke="ivory" cx="264" cy="-490" rx="247.756" ry="18"/>
<text text-anchor="middle" x="264" y="-486.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.0:in:0</text>
</g>
<!-- MN_32&#45;&gt;MN_31 -->
<g id="edge28" class="edge"><title>MN_32&#45;&gt;MN_31</title>
<path fill="none" stroke="black" d="M426.384,-503.592C526.959,-512.063 658.253,-523.122 771.124,-532.628"/>
<polygon fill="black" stroke="black" points="771.033,-536.133 781.292,-533.484 771.621,-529.157 771.033,-536.133"/>
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<!-- M_33 -->
<g id="node33" class="node"><title>M_33</title>
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<text text-anchor="middle" x="264" y="-540.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:source:ROS_exp1_A1</text>
</g>
<!-- MN_32&#45;&gt;M_33 -->
<g id="edge29" class="edge"><title>MN_32&#45;&gt;M_33</title>
<path fill="none" stroke="black" d="M264,-508.141C264,-510.623 264,-513.105 264,-515.587"/>
<polygon fill="black" stroke="black" points="260.5,-515.79 264,-525.79 267.5,-515.79 260.5,-515.79"/>
</g>
<!-- MN_34 -->
<g id="node34" class="node"><title>MN_34</title>
<polygon fill="lightseagreen" stroke="lightseagreen" points="1479.05,-428 781.474,-481.981 781.474,-374.019 1479.05,-428"/>
<text text-anchor="middle" x="1014" y="-431.8" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.1</text>
<text text-anchor="middle" x="1014" y="-416.8" font-family="Times New Roman,serif" font-size="14.00">cell growth</text>
</g>
<!-- MN_32&#45;&gt;MN_34 -->
<g id="edge31" class="edge"><title>MN_32&#45;&gt;MN_34</title>
<path fill="none" stroke="black" d="M428.227,-476.47C528.581,-468.152 658.996,-457.343 771.194,-448.043"/>
<polygon fill="black" stroke="black" points="771.625,-451.519 781.302,-447.205 771.047,-444.543 771.625,-451.519"/>
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<!-- MN_34&#45;&gt;MN_20 -->
<g id="edge32" class="edge"><title>MN_34&#45;&gt;MN_20</title>
<path fill="none" stroke="black" d="M1479.29,-428C1488.21,-428 1497.05,-428 1505.8,-428"/>
<polygon fill="black" stroke="black" points="1506.03,-431.5 1516.03,-428 1506.03,-424.5 1506.03,-431.5"/>
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<!-- MN_35 -->
<g id="node35" class="node"><title>MN_35</title>
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<text text-anchor="middle" x="1014" y="-119.8" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.2</text>
<text text-anchor="middle" x="1014" y="-104.8" font-family="Times New Roman,serif" font-size="14.00">cell growth</text>
</g>
<!-- MN_38 -->
<g id="node38" class="node"><title>MN_38</title>
<ellipse fill="ivory" stroke="ivory" cx="1769" cy="-116" rx="252.655" ry="18"/>
<text text-anchor="middle" x="1769" y="-112.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.2:out:0</text>
</g>
<!-- MN_35&#45;&gt;MN_38 -->
<g id="edge35" class="edge"><title>MN_35&#45;&gt;MN_38</title>
<path fill="none" stroke="black" d="M1479.29,-116C1488.21,-116 1497.05,-116 1505.8,-116"/>
<polygon fill="black" stroke="black" points="1506.03,-119.5 1516.03,-116 1506.03,-112.5 1506.03,-119.5"/>
</g>
<!-- MN_36 -->
<g id="node36" class="node"><title>MN_36</title>
<ellipse fill="ivory" stroke="ivory" cx="264" cy="-116" rx="247.756" ry="18"/>
<text text-anchor="middle" x="264" y="-112.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:s_Hepatotoxicity_ROS.0.2.2:in:0</text>
</g>
<!-- MN_36&#45;&gt;MN_35 -->
<g id="edge33" class="edge"><title>MN_36&#45;&gt;MN_35</title>
<path fill="none" stroke="black" d="M511.737,-116C595.169,-116 688.194,-116 771.237,-116"/>
<polygon fill="black" stroke="black" points="771.313,-119.5 781.313,-116 771.313,-112.5 771.313,-119.5"/>
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<!-- M_37 -->
<g id="node37" class="node"><title>M_37</title>
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<text text-anchor="middle" x="264" y="-166.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:source:ROS_exp1_E8</text>
</g>
<!-- MN_36&#45;&gt;M_37 -->
<g id="edge34" class="edge"><title>MN_36&#45;&gt;M_37</title>
<path fill="none" stroke="black" d="M264,-134.141C264,-136.623 264,-139.105 264,-141.587"/>
<polygon fill="black" stroke="black" points="260.5,-141.79 264,-151.79 267.5,-141.79 260.5,-141.79"/>
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<!-- M_39 -->
<g id="node39" class="node"><title>M_39</title>
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<text text-anchor="middle" x="1769" y="-166.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:sample:exp1&#45;E8&#45;C1</text>
</g>
<!-- MN_38&#45;&gt;M_39 -->
<g id="edge36" class="edge"><title>MN_38&#45;&gt;M_39</title>
<path fill="none" stroke="black" d="M1769,-134.141C1769,-136.623 1769,-139.105 1769,-141.587"/>
<polygon fill="black" stroke="black" points="1765.5,-141.79 1769,-151.79 1772.5,-141.79 1765.5,-141.79"/>
</g>
<!-- MN_48 -->
<g id="node48" class="node"><title>MN_48</title>
<polygon fill="lightseagreen" stroke="lightseagreen" points="2949.45,-178 2281.27,-231.981 2281.27,-124.019 2949.45,-178"/>
<text text-anchor="middle" x="2504" y="-181.8" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.4</text>
<text text-anchor="middle" x="2504" y="-166.8" font-family="Times New Roman,serif" font-size="14.00">fluorescence imaging</text>
</g>
<!-- MN_38&#45;&gt;MN_48 -->
<g id="edge44" class="edge"><title>MN_38&#45;&gt;MN_48</title>
<path fill="none" stroke="black" d="M1932.68,-129.76C2032.06,-138.166 2160.77,-149.053 2270.76,-158.357"/>
<polygon fill="black" stroke="black" points="2270.75,-161.868 2281.01,-159.223 2271.34,-154.893 2270.75,-161.868"/>
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<!-- MN_49 -->
<g id="node49" class="node"><title>MN_49</title>
<polygon fill="lightseagreen" stroke="lightseagreen" points="2949.45,-53 2281.27,-106.981 2281.27,0.981308 2949.45,-53"/>
<text text-anchor="middle" x="2504" y="-56.8" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.5</text>
<text text-anchor="middle" x="2504" y="-41.8" font-family="Times New Roman,serif" font-size="14.00">fluorescence imaging</text>
</g>
<!-- MN_38&#45;&gt;MN_49 -->
<g id="edge46" class="edge"><title>MN_38&#45;&gt;MN_49</title>
<path fill="none" stroke="black" d="M1931.31,-102.135C2030.95,-93.572 2160.43,-82.4431 2270.97,-72.9426"/>
<polygon fill="black" stroke="black" points="2271.6,-76.4013 2281.26,-72.0577 2271,-69.427 2271.6,-76.4013"/>
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<!-- DAN_40 -->
<g id="node40" class="node"><title>DAN_40</title>
<polygon fill="#8470ff" stroke="#8470ff" points="4329.43,-53 3715.29,-76 3715.29,-30 4329.43,-53"/>
<text text-anchor="middle" x="3920" y="-49.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.5</text>
</g>
<!-- DN_43 -->
<g id="node43" class="node"><title>DN_43</title>
<ellipse fill="ivory" stroke="ivory" cx="4722" cy="-53" rx="242.357" ry="18"/>
<text text-anchor="middle" x="4722" y="-49.3" font-family="Times New Roman,serif" font-size="14.00">DN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.5:out:0</text>
</g>
<!-- DAN_40&#45;&gt;DN_43 -->
<g id="edge39" class="edge"><title>DAN_40&#45;&gt;DN_43</title>
<path fill="none" stroke="black" d="M4329.5,-53C4377.19,-53 4424.73,-53 4469.39,-53"/>
<polygon fill="black" stroke="black" points="4469.47,-56.5001 4479.47,-53 4469.47,-49.5001 4469.47,-56.5001"/>
</g>
<!-- MN_41 -->
<g id="node41" class="node"><title>MN_41</title>
<ellipse fill="ivory" stroke="ivory" cx="3230" cy="-53" rx="243.957" ry="18"/>
<text text-anchor="middle" x="3230" y="-49.3" font-family="Times New Roman,serif" font-size="14.00">MN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.0.2.5:out:0</text>
</g>
<!-- MN_41&#45;&gt;DAN_40 -->
<g id="edge37" class="edge"><title>MN_41&#45;&gt;DAN_40</title>
<path fill="none" stroke="black" d="M3474.05,-53C3549.3,-53 3631.63,-53 3704.78,-53"/>
<polygon fill="black" stroke="black" points="3705.04,-56.5001 3715.04,-53 3705.04,-49.5001 3705.04,-56.5001"/>
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<!-- M_42 -->
<g id="node42" class="node"><title>M_42</title>
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<text text-anchor="middle" x="3230" y="-103.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay:a_ROS_experiment1.exp1&#45;E8&#45;C1&#45;Ch2</text>
</g>
<!-- MN_41&#45;&gt;M_42 -->
<g id="edge38" class="edge"><title>MN_41&#45;&gt;M_42</title>
<path fill="none" stroke="black" d="M3230,-71.1406C3230,-73.6226 3230,-76.1046 3230,-78.5865"/>
<polygon fill="black" stroke="black" points="3226.5,-78.7901 3230,-88.7902 3233.5,-78.7902 3226.5,-78.7901"/>
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<!-- D_44 -->
<g id="node44" class="node"><title>D_44</title>
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<text text-anchor="middle" x="4722" y="-103.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay_derived_data:a_ROS_experiment1.data_ROS_experiment1_Ch2.txt (exp1&#45;E8&#45;C1&#45;Ch2)</text>
</g>
<!-- DN_43&#45;&gt;D_44 -->
<g id="edge40" class="edge"><title>DN_43&#45;&gt;D_44</title>
<path fill="none" stroke="black" d="M4722,-71.1406C4722,-73.6226 4722,-76.1046 4722,-78.5865"/>
<polygon fill="black" stroke="black" points="4718.5,-78.7901 4722,-88.7902 4725.5,-78.7902 4718.5,-78.7901"/>
</g>
<!-- DN_46 -->
<g id="node46" class="node"><title>DN_46</title>
<ellipse fill="ivory" stroke="ivory" cx="4722" cy="-678" rx="242.357" ry="18"/>
<text text-anchor="middle" x="4722" y="-674.3" font-family="Times New Roman,serif" font-size="14.00">DN_Hepatotoxicity_ROS:proc:a_ROS_experiment1.2.3.0:out:0</text>
</g>
<!-- DAN_45&#45;&gt;DN_46 -->
<g id="edge42" class="edge"><title>DAN_45&#45;&gt;DN_46</title>
<path fill="none" stroke="black" d="M4329.5,-678C4377.19,-678 4424.73,-678 4469.39,-678"/>
<polygon fill="black" stroke="black" points="4469.47,-681.5 4479.47,-678 4469.47,-674.5 4469.47,-681.5"/>
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<!-- D_47 -->
<g id="node47" class="node"><title>D_47</title>
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<text text-anchor="middle" x="4722" y="-728.3" font-family="Times New Roman,serif" font-size="14.00">Hepatotoxicity_ROS:generic_assay_derived_data:a_ROS_experiment1.data_ROS_experiment1_Ch1.txt (exp1&#45;A1&#45;C1&#45;Ch1)</text>
</g>
<!-- DN_46&#45;&gt;D_47 -->
<g id="edge43" class="edge"><title>DN_46&#45;&gt;D_47</title>
<path fill="none" stroke="black" d="M4722,-696.141C4722,-698.623 4722,-701.105 4722,-703.587"/>
<polygon fill="black" stroke="black" points="4718.5,-703.79 4722,-713.79 4725.5,-703.79 4718.5,-703.79"/>
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<!-- MN_48&#45;&gt;MN_2 -->
<g id="edge45" class="edge"><title>MN_48&#45;&gt;MN_2</title>
<path fill="none" stroke="black" d="M2949.6,-178C2958.42,-178 2967.18,-178 2975.84,-178"/>
<polygon fill="black" stroke="black" points="2975.97,-181.5 2985.97,-178 2975.97,-174.5 2975.97,-181.5"/>
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<!-- MN_49&#45;&gt;MN_41 -->
<g id="edge47" class="edge"><title>MN_49&#45;&gt;MN_41</title>
<path fill="none" stroke="black" d="M2949.6,-53C2958.42,-53 2967.18,-53 2975.84,-53"/>
<polygon fill="black" stroke="black" points="2975.97,-56.5001 2985.97,-53 2975.97,-49.5001 2975.97,-56.5001"/>
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