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Investigate MAF files from the GDC #81

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agduncan94 opened this issue Aug 6, 2020 · 2 comments
Open

Investigate MAF files from the GDC #81

agduncan94 opened this issue Aug 6, 2020 · 2 comments

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@agduncan94
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The GDC has both open and controlled MAF files. See below for more information

Colin made a MAFviewer for JBrowse, is this something we could build upon? Try out the plugin and see if it works for MAF files from the GDC. If it uses a URL, try with the open access MAF files first.

It may be that the MAF files require some processing.

@GFJHogue
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GFJHogue commented Dec 4, 2020

This was more tricky than expected.
MAFviewer requires running commands to convert the MAF files, and the available command options don't support GDC's MAF specification: https://docs.gdc.cancer.gov/Data/File_Formats/MAF_Format/

Since MAF is BED-like I can use our BaseBEDLikeFeature and possibly see if we can still use the View class provided by MAFViewer.

@GFJHogue
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GFJHogue commented Dec 4, 2020

Okay, now I realize that a "UCSC MAF" (the type for use with MAFViewer) is Multiple Alignment Format, and a "GDC MAF" is Multiple Annotation Format.

These are 2 different genomics file-types with the same abbreviation & file extension... 🤦‍♂️

@GFJHogue GFJHogue moved this from In progress to In review in Additional File Type Dec 8, 2020
@GFJHogue GFJHogue moved this from In review to Done in Additional File Type Dec 8, 2020
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