Details

Title of paper

Epistatic interactions promote resistance against direct-acting antivirals targeting the HCV NS3 protein

Authors

Hang Zhang, Ahmed A. Quadeer and Matthew R. McKay

MATLAB Toolboxes Requirements

1. Bioinformatics
2. Communications System
3. Parallel Computing

Usage

1. Open MATLAB
2. Run main.m

Notes

1. For obtaining the sequence data:

   • GLUE database (http://hcv-glue.cvr.gla.ac.uk)

2. For inferring the maximum entropy models:

   • Minimum probability flow method (MPF-BML) (https://github.com/ahmedaq/MPF-BML-GUI)

3. For inferring sectors from the sequences:

   • RocaSec (https://github.com/ahmedaq/RocaSec)

4. For generating the protein structures:

   • Pymol (https://pymol.org)

Troubleshooting

For any questions or comments, please email at hzhangbr@ust.hk.

License

The MIT License (MIT). Please see License File for more information.