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Helper functions for downstream applications

Pretrained Epiphany model weights

  • Trained weights for 10kb resolution model can be obtained from
wget -O pretrained_GM12878.pt_model https://wcm.box.com/shared/static/vv8xzxnurfk8ddjwuc9evkhapl6fj0tu.pt_model
  • Trained weights for 5kb resolution model can be obtained from
wget -O pretrained_GM12878_5kb.pt_model https://wcm.box.com/shared/static/wo6bc6elqw0leivm7w9gnyte6sgos5om.pt_model

Pre-trained weights and sample datasets can also be obtained from Zenodo DOI.

Colab for application examples

  • Generate contact map of GM12878 chromosome 3 using pre-trained model at 10kb resolution: Google colab
  • Generate contact map of a certain region on H1ES cell chromosome 8 [chr8:53167500-55167500] with original and perturbed epigenomic signals using pretrained model at 5kb resolution: Google colab