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MASH template matching #356

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Koeng101 opened this issue Sep 22, 2023 · 2 comments
Closed

MASH template matching #356

Koeng101 opened this issue Sep 22, 2023 · 2 comments
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enhancement New feature or request help wanted Extra attention is needed intermediate Will take some time to fix medium priority The default priority for a new issue.
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@Koeng101
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So, the idea is that I have many templates and many reads. Many of those templates are similar (perhaps only a 4bp difference in 5000bp). I want a method that will be able to tell me the most likely template that those reads belong to - assuming that all the different sequencing reads go to the same template, but are just a little bit noisy (1/50 random mutation or so).

This would greatly help my sequencing pipelines, and I imagine would help other sequencing pipelines.

@Koeng101 Koeng101 added help wanted Extra attention is needed medium priority The default priority for a new issue. intermediate Will take some time to fix enhancement New feature or request labels Sep 22, 2023
@carreter carreter added this to the v1.0 milestone Sep 23, 2023
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This issue has had no activity in the past 2 months. Marking as stale.

@github-actions github-actions bot added the stale label Nov 22, 2023
@TimothyStiles
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There have been demonstrations of template matching using MASH but I'm not so sure if there's anything about extremely small variance between sequences. I'm open to maybe supporting a general template matching function as a demo to start but don't know if I want to maintain that in a stable release yet @Koeng101.

@TimothyStiles TimothyStiles changed the title Mash many sequences MASH template matching Nov 29, 2023
@github-actions github-actions bot removed the stale label Nov 30, 2023
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