unsupported operand type(s) for +: 'float' and 'str'

[YaCui]

Hi,

Thank for develop this usful tool. I got the following error when I run focus finemap. Do you know how to fix it? Thanks!

===================================
FOCUS v0.802

focus finemap
EA_WBC.Chen.2020/EA_WBC_new_munged_chr1.tsv.gz
./1000G_EUR_Phase3_plink/1000G.EUR.QC.1
focus.db
--locations 37:EUR
--p-threshold 5e-07
--chr 1
--out 1_AAA.chr1

Starting log...
[2022-05-18 16:30:57 - INFO] Detecting 1 populations for fine-mapping.
[2022-05-18 16:30:57 - INFO] As a result, running single-population FOCUS.
[2022-05-18 16:30:57 - INFO] Preparing GWAS summary file for population at EA_WBC.Chen.2020/EA_WBC_new_munged_chr1.tsv.gz.
[2022-05-18 16:31:05 - INFO] Preparing reference SNP data for population at ./1000G_EUR_Phase3_plink/1000G.EUR.QC.1.
[2022-05-18 16:31:11 - INFO] Preparing weight database at focus.db.
[2022-05-18 16:31:12 - INFO] Preparing user-defined locations at 37:EUR.
[2022-05-18 16:31:12 - INFO] Found 1703 independent regions on the entire genome.
[2022-05-18 16:31:12 - INFO] 133 independent regions currently used after being filtered on chromosome, start, and stop.
[2022-05-18 16:31:12 - INFO] Preparing data at region 1:10583-1:1892607. Skipping if following warning occurs.
[2022-05-18 16:31:12 - INFO] Deciding prior probability for a gene to be causal.
[2022-05-18 16:31:12 - INFO] Using gencode file prior probability 0.007575757575757576.
[2022-05-18 16:31:12 - WARNING] No GWAS SNPs with p-value < 5e-07 found at region 1:10583-1:1892607 at EA_WBC.Chen.2020/EA_WBC_new_munged_chr1.tsv.gz. Skipping.
[2022-05-18 16:31:13 - INFO] Preparing data at region 1:4380811-1:5913893. Skipping if following warning occurs.
[2022-05-18 16:31:13 - INFO] Deciding prior probability for a gene to be causal.
[2022-05-18 16:31:13 - INFO] Using gencode file prior probability 0.09090909090909091.
[2022-05-18 16:31:13 - WARNING] No GWAS SNPs with p-value < 5e-07 found at region 1:4380811-1:5913893 at EA_WBC.Chen.2020/EA_WBC_new_munged_chr1.tsv.gz. Skipping.
[2022-05-18 16:31:13 - INFO] Preparing data at region 1:5913893-1:7247335. Skipping if following warning occurs.
[2022-05-18 16:31:13 - INFO] Deciding prior probability for a gene to be causal.
[2022-05-18 16:31:14 - INFO] Using gencode file prior probability 0.03125.
[2022-05-18 16:31:14 - WARNING] No GWAS SNPs with p-value < 5e-07 found at region 1:5913893-1:7247335 at EA_WBC.Chen.2020/EA_WBC_new_munged_chr1.tsv.gz. Skipping.
[2022-05-18 16:31:14 - INFO] Preparing data at region 1:7247335-1:9365199. Skipping if following warning occurs.
[2022-05-18 16:31:14 - INFO] Deciding prior probability for a gene to be causal.
[2022-05-18 16:31:14 - INFO] Using gencode file prior probability 0.018867924528301886.
[2022-05-18 16:32:24 - INFO] Fine-mapping starts at region 1:7247335-1:9365199.
[2022-05-18 16:32:24 - INFO] Aligning GWAS, LD, and eQTL weights for the single population. Region 1:7247335-1:9365199 will skip if following errors occur.
[2022-05-18 16:32:24 - ERROR] unsupported operand type(s) for +: 'float' and 'str'
[2022-05-18 16:32:24 - INFO] Finished TWAS & fine-mapping. Thanks for using FOCUS, and have a nice day!