A novel approach to optimize Brain Stimulation: structural connectivity guided individual neuronavigation

[Remi-Gau]

Added as an issue for book keeping

Source:

https://brainhack.ch/past_events/opengeneva2019/index.html#TMS_tracto

Leader:

Takuya Morishita, Philipp Koch and Olivier Reynaud

Transcranial magnetic stimulation (TMS) is used to study electrophysiological fundaments of brain function. Besides this TMS has the outstanding opportunity of non-invasive neuromodulation of the cortex, a promising treatment concept for multiple diseases like e.g., stroke or depression. Hereby, specific brain areas are targeted using T1 weighted MR images of the subject guided by anatomical landmarks. Still, this does not consider individual underlying anatomical and functional features including e.g., white matter connections. To move towards personalized precision medicine in neuromodulation, incorporating individual patient characteristics in treatment planning is inevitable. Taken toegther, this project aims to precise the targeting of brain areas for TMS using individual structural connectivity estimates.