signifinder is an R package that collects and implements 53
expression-based signatures from cancer literature. Through the analysis
of expression data with the collected signatures, signifinder can
attribute to each sample a score per signature that summarizes many
different tumor aspects, such as predict the response to therapy or the
survival association, as well as quantify multiple microenvironmental
conditions, such as hypoxia or the activity of the immune response.
The signifinder package is available from
Bioconductor,
where a vignette containing examples and documentation is included.
The signifinder package can be installed from Bioconductor:
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("signifinder")