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Investigating the Influence of Growth Arrest Mechanisms on Tumour Responses to Radiotherapy

This repository contains the MATLAB code used to generate the three virtual tumour populations studied in the paper "Investigating the Influence of Growth Arrest Mechanisms on Tumour Responses to Radiotherapy" [1] and to numerically solve the ODE model for radiotherapy response proposed in [1]. All details for how to run the codes, can be found in the MATLAB scripts. For reproducibility purposes, we also include a spreadsheet that contains the parameter sets that define the three virtual cohorts.

References

  • [1] Colson, C., Maini, P.K. and Byrne, H.M., 2023. Investigating the Influence of Growth Arrest Mechanisms on Tumour Responses to Radiotherapy. Bulletin of Mathematical Biology, 85, p.74. https://doi.org/10.1007/s11538-023-01171-2