Inability to Recognize Certain Norovirus Subtypes

[LDL0315]

Feedback

I want to express my appreciation for this virus sequencing analysis software—it's the best I've ever used. Many thanks to the authors and the entire team for their hard work!

During practical sample analysis, we encountered an issue where the software struggles to identify certain genotypes of the Norovirus, such as GII.13[P21] and GI.3[P10], leading to false-negative results.

Request

I propose expanding the existing virus database to encompass a broader range of virus subtypes. This enhancement could potentially mitigate false-negative results and enhance the overall performance of the software.

Additional Information

• Software Version: v0.2.3
• Software Version: DB_v2.0.2.tar.gz

Thank you for your attention and dedication to improving this exceptional software!

[mtisza1]

Hi,

Thank you for your nice comments and for opening this request. We are planning to work on more accurate methods to make strain-level taxonomy calls for detected viruses.

Unfortunately, it will probably be a few months until this module is ready.

I'll tag you when this update is done.

Mike