BM.4.1.1 sublineage with S:F486P recently emerged in Indonesia and already exported to New Zealand, Denmark and Australia - 14 sequences

[FedeGueli]

Here i want to propose to further monitor its eventual spread a sublineage of BM.4.1.1 carrying S:F486P.
As mentioned in the issue for the chilean BM.1.1.3 + S:F486P this mutation seems on the rise globally especially in recombinant lineages but it is worth monitor also the smaller one like this especially when they were able to be exported internationally as this one did.

Tree:
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_209ac_51d500.json?label=nuc%20mutations:T14565A

Defining mutations
BM.4.1.1 + > ORF1b:Q2425R (A20741G) > T14565A > T13090C, S:F486P (T23018C)

Sequences:
EPI_ISL_15826757, EPI_ISL_15901229, EPI_ISL_15901239,
EPI_ISL_15901257 From Indonesia

EPI_ISL_15910914 from Denmark

Edited

Gisaid query : NSP16_Q28R,Spike_F486P,E_T11A,NSP14_V182I

[FedeGueli]

One more sequence of this came today from Australia interesting it clusters with an indonesian sequence and share with it a further RBD mutation S:S494P

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_22afe_698140.json?c=userOrOld&label=id:node_7614120

@corneliusroemer @InfrPopGen @thomasppeacock

[FedeGueli]

@corneliusroemer @thomasppeacock @InfrPopGen 8 new sequences of this one uploaded today:
one from Indonesia an hospitalized 72yrs old and 7 from New Zealand five of them defined by Orf3a:W128L and two by S:S494T.

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_1476d_7d38f0.json?label=id:node_7622214

[corneliusroemer]

This looks interesting, thanks @FedeGueli - I'll designate based on international spread, fast growth and known mutations.