Potential BA.2.75/BA.5 recombinant (51 seq., 7 countries)

[agamedilab]

Proposal for a sublineage of BA.2.75/BA.5
Earliest sequence: 22.12.2022 (Singapore)
Countries detected: Singapore, USA, UK, Austria

This is a potential recombinant between sublineages of BA.2.75/BA.5 which was detected in four countries so far (Singapore, USA, UK, Austria). Nextclade identifies the sequences as XBP while usher clusters them within BA.2.75.

Defining Mutations:
nuc unique C5748A, G21893A, C22747T, C23595T, T25975C
nuc homoplasies C11124T, T13324C
ORF1ab unique T1828N
ORF1ab homoplasies A3620V
S unique D111N, T678I
ORF3a unique S195P

Potential Gisaid query: C5748A, G21893A, C22747T, C23595T, T25975C

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_30d99_368450.json?c=gt-S_111

EPI_ISL_16352127, EPI_ISL_16415291, EPI_ISL_16676426,
EPI_ISL_16907101, EPI_ISL_16946169, EPI_ISL_16952041,
EPI_ISL_16952045, EPI_ISL_16969074, EPI_ISL_16976933,
EPI_ISL_16977008, EPI_ISL_16978835

[agamedilab]

29 on usher as of 09.03.23.

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_8a6c_9ce000.json?c=userOrOld&label=id:node_7974580

[agamedilab]

51 on usher as of 24.03.23

https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_43798_d91360.json?label=id:node_8042988

[InfrPopGen]

Hi @agamedilab I feel this can be closed because it reminds me very much of #1752 which has already been designated.

[agamedilab]

@InfrPopGen many thanks for pointing this out!