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XBB.1.9.1 sublineage with S:A411S emerged in China (85 seqs in China and Australia) #1996

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HynnSpylor opened this issue May 16, 2023 · 6 comments
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@HynnSpylor
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Defining mutations: XBB.1.9.1>C503T(ORF1a:P80S)>G22793T(S:A411S), then mostly further get C13011T(ORF1a:T4249I), G10658A (ORF1a:V3465I)
GISAID query: Spike_A411S, C503T, G5720A, C11956T
Earliest seq: 2023-04-19 (China, EPI_ISL_17618478)
Most recent seq: 2023-05-08 (Australia, EPI_ISL_17662973)
Countries detected: China (45, Sichuan Province 28, Hubei Province 13, Shanghai Municipality 2, Jiangsu Province 1, Qinghai Province 1), Australia (1)

Usher Tree:
QQ截图20230516161344
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_12505_336e00.json

A very new sublineage in China with fast growth. Today it is detected abroad (in Australia) and many seqs in Sichuan Province are updated.
Nowadays XBB.1.9.1 is the dominant sublineage in China, and we may keep monitoring.

Genomes:
EPI_ISL_17614986, EPI_ISL_17615014, EPI_ISL_17618478, EPI_ISL_17625318, EPI_ISL_17625363, EPI_ISL_17625367-17625369,
EPI_ISL_17625382, EPI_ISL_17625403, EPI_ISL_17625414, EPI_ISL_17625487, EPI_ISL_17632947, EPI_ISL_17632949, EPI_ISL_17632956, EPI_ISL_17632961, EPI_ISL_17637415, EPI_ISL_17637509, EPI_ISL_17645406, EPI_ISL_17645409-17645411, EPI_ISL_17645418-17645419, EPI_ISL_17645455, EPI_ISL_17645477, EPI_ISL_17645514, EPI_ISL_17652411, EPI_ISL_17662973, EPI_ISL_17664525,
EPI_ISL_17664531-17664532, EPI_ISL_17664538, EPI_ISL_17664548, EPI_ISL_17664555, EPI_ISL_17664560, EPI_ISL_17664568, EPI_ISL_17664579-17664580, EPI_ISL_17664584, EPI_ISL_17664586, EPI_ISL_17664594-17664595, EPI_ISL_17664615, EPI_ISL_17664624-17664625

@Last-Order
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50 seqs now. 4 more from Hubei.

@HynnSpylor
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51 seqs (1 updated from Shanghai)

@HynnSpylor HynnSpylor changed the title XBB.1.9.1 sublineage with S:A411S emerged in China (46 seqs in China and Australia) XBB.1.9.1 sublineage with S:A411S emerged in China (51 seqs in China and Australia) May 18, 2023
@HynnSpylor
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It rapidly increases to 74 (all new seqs are updated from China).

@HynnSpylor HynnSpylor changed the title XBB.1.9.1 sublineage with S:A411S emerged in China (51 seqs in China and Australia) XBB.1.9.1 sublineage with S:A411S emerged in China (74 seqs in China and Australia) May 19, 2023
@FedeGueli
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@corneliusroemer @thomaspeacock @InfrPopGen @AngieHinrichs i suggest a rapid designation of this one.

@Last-Order
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76 seqs now. 2 new from Fujian.

@HynnSpylor HynnSpylor changed the title XBB.1.9.1 sublineage with S:A411S emerged in China (74 seqs in China and Australia) XBB.1.9.1 sublineage with S:A411S emerged in China (85 seqs in China and Australia) May 23, 2023
@AnonymousUserUse
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Designated as FL.13.1

@InfrPopGen InfrPopGen added this to the FL.13.1 milestone May 29, 2023
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