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Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（628 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） #2000

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Memorablea opened this issue May 19, 2023 · 51 comments
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Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（628 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） #2000

Memorablea opened this issue May 19, 2023 · 51 comments
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FY.3.2

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@Memorablea
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Memorablea commented May 19, 2023 •
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Transferred from sars-cov-2-variants/lineage-proposals#64

Lineage of:XBB.1.22.1.3 with ORF1ab: E3764G (A11556G) = NSP6_E195G
Earliest sequence:2023-03-31
Most recent sequence:2023-05-11
GISAID Search： G2513A,C23191T,A11556G

sequence：

Genomes: EPI_ISL_17652363，EPI_ISL_17645500，EPI_ISL_17645475，EPI_ISL_17645474，EPI_ISL_17645465，EPI_ISL_17645449，EPI_ISL_17645441，EPI_ISL_17645433，EPI_ISL_17625392，EPI_ISL_17625374，EPI_ISL_17625364，EPI_ISL_17625345，EPI_ISL_17625330，EPI_ISL_17625308，EPI_ISL_17625289，EPI_ISL_17625288，EPI_ISL_17625287，EPI_ISL_17625282，EPI_ISL_17625271，EPI_ISL_17625270，EPI_ISL_17625263，EPI_ISL_17615025，EPI_ISL_17615020，EPI_ISL_17615013，EPI_ISL_17615000，EPI_ISL_17614998，EPI_ISL_17614996，EPI_ISL_17614995，EPI_ISL_17614993，EPI_ISL_17614990，EPI_ISL_17614982，EPI_ISL_17614981，EPI_ISL_17614978，EPI_ISL_17545759，EPI_ISL_17545753，EPI_ISL_17545732，EPI_ISL_17545718，EPI_ISL_17545717，EPI_ISL_17545710，EPI_ISL_17545698，EPI_ISL_17545692，EPI_ISL_17545691，EPI_ISL_17545687，EPI_ISL_17545671，EPI_ISL_17545653，EPI_ISL_17545645，EPI_ISL_17545641，EPI_ISL_17511956，EPI_ISL_17501449，EPI_ISL_17485743，EPI_ISL_17684362，EPI_ISL_17684361，EPI_ISL_17684324，EPI_ISL_17684111，EPI_ISL_17672060，EPI_ISL_17672048，EPI_ISL_17672032，EPI_ISL_17672021，EPI_ISL_17672018，EPI_ISL_17672003，EPI_ISL_17671999，EPI_ISL_17671996，EPI_ISL_17671993，EPI_ISL_17671987，EPI_ISL_17671986，EPI_ISL_17671955，EPI_ISL_17671935，EPI_ISL_17671932，EPI_ISL_17671918，EPI_ISL_17671909，EPI_ISL_17671898，EPI_ISL_17671895

image
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/singleSubtreeAuspice_genome_17caa_761010.json?label=id:node_3638243

Editor: Thank you @FedeGueli
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@Memorablea
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One from Fujian.
EPI_ISL_17689380

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (72seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (73seqs) May 21, 2023
@Memorablea Memorablea mentioned this issue May 22, 2023
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@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (73seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (82seqs) May 23, 2023
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82 seqs now

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (82seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (83seqs) May 24, 2023
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One from Fujian. 83 seqs now

@Memorablea
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Four sequences from Hubei

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (83seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (87seqs) May 26, 2023
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One sequences from Sichuan

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (87seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (88seqs) May 27, 2023
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6 from Shanghai and 1 from Hubei.95 seqs now.

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (88seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (95seqs) May 30, 2023
@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (95seqs) The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (95 seqs) May 30, 2023
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Today's from Hubei and Anhui.110 seqs now.

@Memorablea Memorablea changed the title The subfamily of FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G = NSP6_E195G) appears in China (95 seqs) Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（110 seqs） May 31, 2023
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Memorablea commented Jun 1, 2023 •
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At present, there are 112 items, which continue to grow. I suggest specifying it.

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（110 seqs） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（112 seqs） Jun 1, 2023
@FedeGueli
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@corneliusroemer this has a growth rate comparable to the one FL.2+ Orf1b:K1383R , i think along with the super fast EG.5.1 + orf1b:D54N are the three to prioritize without any additional spike mutation.
https://cov-spectrum.org/explore/Asia/AllSamples/Past2M/variants?aaMutations=Orf1b%3AK1383R&aaMutations1=ORF1a%3AE3764G&analysisMode=CompareToBaseline&

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Memorablea commented Jun 3, 2023 •
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1 from Anhui

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（112 seqs） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（113 seqs） Jun 3, 2023
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Sequence from June 5th: This branch has already leaked to France, with another one from Anhui.

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（113 seqs） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（115 seqs from 2 countries） Jun 7, 2023
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Memorablea commented Jun 7, 2023 •
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4 from Shanghai

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（115 seqs from 2 countries） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（119 seqs from 2 countries） Jun 7, 2023
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120 now

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（119 seqs from 2 countries） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（120 seqs from 2 countries） Jun 8, 2023
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124 NOW

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（120 seqs from 2 countries） Continuously growing FY.3 (XBB. 1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（124 seqs from 2 countries） Jun 9, 2023
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He should have been designated because there are currently 125 sequences (continuously increasing), and this lineage has been dispersed to three countries (China, France, and the United States) since it was born in China.@corneliusroemer

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（293 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（323 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Jul 16, 2023
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323 now

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cc @corneliusroemer

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（323 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（324 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Jul 18, 2023
@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（324 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（359 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Jul 22, 2023
@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（359 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（435 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Jul 28, 2023
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@FedeGueli @corneliusroemer @AngieHinrichs @InfrPopGen

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FedeGueli commented Jul 28, 2023 •
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@FedeGueli @corneliusroemer @AngieHinrichs @InfrPopGen

@corneliusroemer i think it should be designated it is a clear big branch of FY.3 likely one of the biggest lineage in circulation 8as number of infections i mean)

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NkRMnZr commented Aug 1, 2023

checking with Cov-Spectrum, local prevalence in China is quite significant for some time already.
uptick

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（435 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（460 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 2, 2023
@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（460 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（472 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 4, 2023
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image

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（472 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（523 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 10, 2023
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FedeGueli commented Aug 10, 2023 •
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please add the link of the comparison. I think this is going on circulating where EG.5.1 arose , keeping a solid 10% of share in Hubei in the samples collected after 15/07

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thx you

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（523 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（526 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 14, 2023
@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（526 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（574 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 19, 2023
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574 now

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594now

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（574 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（594 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 22, 2023
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601 now

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（594 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（601 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 25, 2023
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616now

@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（601 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（616 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 28, 2023
@Memorablea Memorablea changed the title Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（616 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Continuously growing FY.3 (XBB.1.22.1.3) and ORF1ab: E3764G (A11556G=NSP6-E195G) appear in China（628 seqs, from China, South Korea, United States, Australia, France, Germany, Canada, Laos, Singapore,Austria, Malaysia,Japan，Luxembourg） Aug 29, 2023
@Memorablea
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628now

@corneliusroemer corneliusroemer added this to the FY.3.2 milestone Aug 31, 2023
@Memorablea
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thanks

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