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XBC.1.6 sublineage with S:V445A circulating in South Australia (49) - 3% of prevalence in August #2197

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FedeGueli opened this issue Aug 17, 2023 · 5 comments

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@FedeGueli
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Transferred from sars-cov-2-variants/lineage-proposals#203

This lineage seemed deemd to dying off when in the new batch from South Australia uploaded there were 11 samples belonging to it.
I updated the query cause it was not perfect:

Gisaid query : T8707C,T22896C,C10156T

Defining mutations:
XBC.1.6 >>T8707C, C26735T > C10156T > C29762T > S:V445A (T22896C)

Samples: 39 all from S.Australia (prevalence during July around 5%)
First: 2023-05-25
Last:2023-08-01

IDs EPI_ISL_17793665, EPI_ISL_17793682, EPI_ISL_17793695, EPI_ISL_17793826, EPI_ISL_17793913, EPI_ISL_17849502, EPI_ISL_17849512, EPI_ISL_17849599, EPI_ISL_17849602, EPI_ISL_17849709, EPI_ISL_17849740, EPI_ISL_17999363, EPI_ISL_17999375, EPI_ISL_17999401, EPI_ISL_17999414, EPI_ISL_17999429, EPI_ISL_18000038, EPI_ISL_18000047, EPI_ISL_18000081, EPI_ISL_18000084, EPI_ISL_18000114, EPI_ISL_18000194, EPI_ISL_18000208, EPI_ISL_18000240, EPI_ISL_18000244, EPI_ISL_18000264, EPI_ISL_18000298, EPI_ISL_18000306, EPI_ISL_18109322, EPI_ISL_18109324-18109325, EPI_ISL_18109362, EPI_ISL_18109364, EPI_ISL_18109367-18109368, EPI_ISL_18109370, EPI_ISL_18109376, EPI_ISL_18109509, EPI_ISL_18109511

Tree:
Schermata 2023-08-18 alle 00 14 41
Schermata 2023-08-18 alle 00 14 53

Schermata 2023-08-18 alle 00 15 27
https://nextstrain.org/fetch/genome.ucsc.edu/trash/ct/subtreeAuspice1_genome_27975_e9b960.json?c=gt-S_445&label=id:node_6399900

@FedeGueli FedeGueli changed the title XBC.1.6 sublineage with S:V445A circualting in South Australia (39) - 5% of prevalence in July XBC.1.6 sublineage with S:V445A circulating in South Australia (39) - 5% of prevalence in July Aug 17, 2023
@FedeGueli FedeGueli changed the title XBC.1.6 sublineage with S:V445A circulating in South Australia (39) - 5% of prevalence in July XBC.1.6 sublineage with S:V445A circulating in South Australia (42) - 3% of prevalence in August Aug 31, 2023
@FedeGueli
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FedeGueli commented Aug 31, 2023

Prevalence of this one is going down. lets wait the last updload of samples collected in August before closing it .

@FedeGueli FedeGueli changed the title XBC.1.6 sublineage with S:V445A circulating in South Australia (42) - 3% of prevalence in August XBC.1.6 sublineage with S:V445A circulating in South Australia (43) - 3% of prevalence in August Sep 4, 2023
@FedeGueli
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FedeGueli commented Sep 4, 2023

only 6 samples in august closing it for now.

@FedeGueli FedeGueli closed this as not planned Won't fix, can't repro, duplicate, stale Sep 4, 2023
@NkRMnZr
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NkRMnZr commented Sep 12, 2023

49 now

@FedeGueli FedeGueli changed the title XBC.1.6 sublineage with S:V445A circulating in South Australia (43) - 3% of prevalence in August XBC.1.6 sublineage with S:V445A circulating in South Australia (49) - 3% of prevalence in August Sep 12, 2023
@FedeGueli FedeGueli reopened this Sep 12, 2023
@FedeGueli
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Reopening. it seems slow to me.

@FedeGueli
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Designated JT.1 via 0f50930

FedeGueli referenced this issue Oct 14, 2023
@AngieHinrichs: The V445A is probably artefactually split into two by
a dropouty C29762T
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