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HK.3 with S:L452Q (13 seq, Australia, USA) #2357

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Sinickle opened this issue Nov 2, 2023 · 3 comments
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HK.3 with S:L452Q (13 seq, Australia, USA) #2357

Sinickle opened this issue Nov 2, 2023 · 3 comments

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@Sinickle
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Sinickle commented Nov 2, 2023

GISAID Query: G18332A, T22917A, T15408C
Earliest Sequence: Sep 17, Australia NSW - EPI_ISL_18324789
Countries: Australia - 12 (multiple regions), USA - 1

Mutations:
ORF1a:V2238A,
ORF1b:R1622K,
S:L452Q,
ORF3a:M5I
C2662T, T2698C, A3019G, T6978C, T15408C, G18332A, T22917A, T24709C, G25407T

USHER
image

Discussion:
11/13 of the sequences at the moment are in October. There are sequences for Australian regions SA, WA, QLD, NSW. The New York sequence is baseline surveillance, so likely not directly travel-related.
At the moment, this is the largest XBB lineage that has both an S:452 and an S:455 mutation.

@FedeGueli
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@corneliusroemer proposed directly here you have to add the milestone

@FedeGueli
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Ok the parental branch with G25407T(ORF3a:M5I) > C2662T is Branch 46 in sars-cov-2-variants/lineage-proposals#537

@corneliusroemer
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Surprise appearance in South Africa, two times

At 59 sequences now in GISAID, not massively fast but also not bad

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