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JN.1+S:V1104L emerging in India(Designated JN.1.11, 16 and 5 countries with Orf1a:T2283I and S:F456L ) #2446

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aviczhl2 opened this issue Jan 10, 2024 · 8 comments
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@aviczhl2
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aviczhl2 commented Jan 10, 2024

From sars-cov-2-variants/lineage-proposals#1253 branch 4 and sars-cov-2-variants/lineage-proposals#1262

JN.1+G17334T,G24872T(S:V1104L)

GISAID query: G24872T, G17334T,C28958A
No. of seqs: 21(India 20 UK 1)

First: EPI_ISL_18694669, India-GJ, 2023-12-7
Latest: EPI_ISL_18725672, India-MH, 2024-1-1

20/790=2.5% in India seqs from 2023-12. From GJ, KA and MH.

+C7113T,T22928C(Orf1a:T2283I,S:F456L)
GISAID query: C7113T,T22928C,T3565C
No. of seqs: 6(India 5 UK 1)

Note that due to artefacts usher places those seqs on different branches. Some with S:V483G artefact are placed together,
some with artefacts around S:16 are placed together, and seqs with other artefacts are placed in other places.

@AngieHinrichs

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image

@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(16 seqs, 2 countries, 6 with Orf1a:T2283I and S:F456L, 2% India) JN.1+S:V1104L emerging in India(21 seqs, 2 countries, 6 with Orf1a:T2283I and S:F456L, 2.5% India) Jan 10, 2024
@corneliusroemer
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Also found this one - it's a bit tricky to designate due to the artefacts, there's now an Israeli sequence as well though with 456L hCoV-19/England/CLIMB-CM7YMUES/2023|EPI_ISL_18735395|2023-12-29

And two Texas seqs without 456L:

hCoV-19/USA/TX-HMH-M-136910/2023|EPI_ISL_18743029|2023-12-27
hCoV-19/USA/TX-HMH-M-136429/2023|EPI_ISL_18743507|2023-12-15

@corneliusroemer
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I've designated via the non-Indian sequences with 1104L for now as JN.1.11, the 456L would be a sublineage in the future

@corneliusroemer corneliusroemer added this to the JN.1.11 milestone Jan 11, 2024
@AngieHinrichs
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Yep, it's currently placed on a messy reversion branch within JN.1.1 instead of JN.1. When the 2024-01-11 build finishes I will do some pruning & re-optimization on the tree, and then hopefully in tomorrow's 2024-01-12 build JN.1.11 will be in the right place.

@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(21 seqs, 2 countries, 6 with Orf1a:T2283I and S:F456L, 2.5% India) JN.1+S:V1104L emerging in India(21 seqs, 2 countries, 8 with Orf1a:T2283I and S:F456L, 2.5% India) Jan 12, 2024
@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(21 seqs, 2 countries, 8 with Orf1a:T2283I and S:F456L, 2.5% India) JN.1+S:V1104L emerging in India(Designated JN.1.11, 8 with Orf1a:T2283I and S:F456L) Jan 14, 2024
@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(Designated JN.1.11, 8 with Orf1a:T2283I and S:F456L) JN.1+S:V1104L emerging in India(Designated JN.1.11, 10 with Orf1a:T2283I and S:F456L) Jan 15, 2024
@aviczhl2
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The S:F456L branch is 10 now.

@FedeGueli
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456L 15 now

@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(Designated JN.1.11, 10 with Orf1a:T2283I and S:F456L) JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 with Orf1a:T2283I and S:F456L, USA,UK,India,Singapore,Israel) Jan 17, 2024
@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 with Orf1a:T2283I and S:F456L, USA,UK,India,Singapore,Israel) JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 and 5 countries with Orf1a:T2283I and S:F456L, ) Jan 17, 2024
@aviczhl2
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Countries for F456L branch:
India, UK, USA, Israel, Singapore

@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 and 5 countries with Orf1a:T2283I and S:F456L, ) JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 and 5 countries with Orf1a:T2283I and S:F456L ) Jan 17, 2024
@FedeGueli
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I've designated via the non-Indian sequences with 1104L for now as JN.1.11, the 456L would be a sublineage in the future

@corneliusroemer could you reopen this one to track properly the 456L branch please?

@aviczhl2 aviczhl2 changed the title JN.1+S:V1104L emerging in India(Designated JN.1.11, 15 and 5 countries with Orf1a:T2283I and S:F456L ) JN.1+S:V1104L emerging in India(Designated JN.1.11, 16 and 5 countries with Orf1a:T2283I and S:F456L ) Jan 19, 2024
@Over-There-Is
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JN.11> A12889G> T3055C> T22926C or JN.11.1> T3055C?

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