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JN.1 with S:A1087S > S:R346T > S:F59S [17 with 346, US east coast + 1 Canada] #2464

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corneliusroemer opened this issue Jan 17, 2024 · 2 comments
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@corneliusroemer
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corneliusroemer commented Jan 17, 2024

GISAID query: C26894T,C25680T,G24821T

Could be that 346T becomes increasingly beneficial as immunity to JN.1 without 346T develops. The first 346T lineages e.g. in France didn't seem to have growth advantage. Maybe that's changing now.

JN.1 with S:A1087S > S:R346T > S:F59S [17 with 346, US east coast + 1 Canada]

image

Tricky thing here is that it's not clear how to break into sublineages, if at all. I'd prefer to wait a few more days to see where it makes sense to delineate.

image

https://nextstrain.org/fetch/genome-test.gi.ucsc.edu/trash/ct/subtreeAuspice1_genome_test_29456_810590.json

@ujoshi4
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ujoshi4 commented Jan 22, 2024

This seems to be the best S:R346T branch with that S2 mutation that might be evasive.

@FedeGueli
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Designated JN.1.13 starting with S:A1078S via d68c064

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