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I am not one of the developers, but this looks like just an issue with your python.
May I ask which operative system are you using?
Also, can you please run the command which python and paste here the output?
It might just be that hisat2-build looks for your python installation and it cannot find it where it expects it.
When I type hisat2-build in the hisat2 directory, it doesn't work for me and shows this error:" /usr/bin/env: ‘python’: No such file or directory"
While I can run hisat2 easily, hisat2-build doesn't run for me.
Thank you for your help in advance...
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