Use updated uniclust database

[ihbxiongjie]

There is an updated uniclust database "UniRef30_2021_06_hhsuite.tar.gz", is it OK to instead it as the 2018 version?

[Shall-We-Dance]

Yes, I've tried to update the uniclust database, and it works.

One of my collaborator gave me a sequence that will meet "HHblits fail" on 2018 version, this problem is solved when using 2020 version.

BTW, you need to change the run_docker.py at the sametime.

• download 2020_06 version to <DOWNLOAD_DIR>/uniclust30.

• Tar it as a folder named uniclust30_2020_06, then vim the ./docker/run_ducker.py in line 122

  from

  FLAGS.data_dir, 'uniclust30', 'uniclust30_2018_08', 'uniclust30_2018_08’)

  to

  FLAGS.data_dir, 'uniclust30', 'uniclust30_2020_06', 'UniRef30_2020_06')

You can use 2021 version as well.

[Augustin-Zidek]

Yes, it is absolutely OK to use a more recent version of any of the databases (but note that you will probably get slightly different results). The instructions from @Shall-We-Dance are great.