The tool provides futility interim analysis plan using the Bayesian predictive design in single arm early phase II clinical trial. It also generates statistical plan so clinicians could easily incorporate it into the clinical trial protocol. (reference: Application of Bayesian predictive probability for interim analysis in single-arm early phase II trial. Chen et al; submitted).
- The shiny applictaion provides futility interim analysis plan for the Bayesian predictive design design in single arm early phase II clinical trial and generates a statistical plan to be easily incorporated into the clinical trial protocol.
Simply run the following from an R console:
if (!require("devtools"))
install.packages("devtools")
devtools::install_github("dungtsa/BayesianPredictiveFutility",force = TRUE)library("BayesianPredictiveFutility")
Bayesian_Predictive_App()Procedure of BayesianPredictiveFutility R Shiny App
Example of two-stage case
Example of three-stage case
Example of multi-stage case