Generalization of QTL mapping

[veitveit]

QTL mapping is so far narrow synonym of genetic mapping but is also applicable to other chromatin features such as histone modifications, chromatin accessibility, ...

Solution 1: Leave as is and generalize definition of genetic mapping

Solution 2: Diversify children of DNA mapping to include all chromatin features

[joncison]

Currently we have:

• Genetic mapping hasNarrowSynonym QTL mapping
  but
• Haplotype mapping is_a Genetic mapping

So there's a discrepancy in the modelling. I think my preference is

Solution 1: Leave as is and generalize definition of genetic mapping - but that would mean deprecating Haplotype mapping making this a narrowSynonym. This makes EDAM simpler == good.

Unless there are many examples of tools which e.g. do Haplotype mapping but not QTL mapping, in which case Solution 2 may be preferable.

I rather suspect the tools out there, each do various types of Genetic mapping, hence Solution 1, but I'd like some advise here cc @veitveit @matuskalas

[matuskalas]

A hard question...

We can also consider either 2 separate but overlapping concepts, or hasRelatedSynonym. I also guess that QTL mapping is perhaps a more often used term than Genetic mapping, but that may not be the most relevant criterium.