adaptive filter runtime error

[seichhorn]

I've been encountering this error in my most recent data analyses during the adaptive filtering. Have you run into this, or have a sense of what this might be about? I can dig into it more tomorrow.

File "/n/home13/seichhorn/MERlin/merlin/analysis/filterbarcodes.py", line 379, in _run_analysis
self.parameters['misidentification_rate'])
File "/n/home13/seichhorn/MERlin/merlin/analysis/filterbarcodes.py", line 178, in calculate_threshold_for_misidentification_rate
args=[targetMisidentificationRate], tol=0.001, x1=0.3)
File "/n/home13/seichhorn/.conda/envs/MERlin/lib/python3.6/site-packages/scipy/optimize/zeros.py", line 340, in newton
raise RuntimeError(msg)
RuntimeError: Tolerance of -0.003639641998025245 reached. Failed to converge after 7 iterations, value is 0.44139608611659104.

[emanuega]

That indicates that it isn’t able to find a threshold that achieves the specified misidentification rate. This could either be because the initial conditions are not close enough to the optimal value or the desired misidentification rate is not achievable.

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> On Oct 10, 2019, at 6:26 PM, seichhorn ***@***.***> wrote:  Assigned #24 to @emanuega. — You are receiving this because you were assigned. Reply to this email directly, view it on GitHub, or unsubscribe.