https://newsd.in/tocilizumab-improves-survival-in-critically-ill-covid-patients-study/ In a major breakthrough, researchers including one of Indian-origin have found that tocilizumab drug reduced mortality by 30 per cent among critically ill Covid-19 patients when administered within the first two days of ICU admission.
For the study, published in the journal JAMA Internal Medicine, the research team investigated the effects of the anti-inflammatory drug tocilizumab on critically ill patients with laboratory-confirmed Covid-19.
“Unlike steroids, which suppress the immune system more broadly, tocilizumab specifically inhibits the receptor for the pro-inflammatory cytokine, IL-6,” said the study authors from Brigham and Women’s Hospital in the US.
https://twitter.com/__ice9/status/1318853314285547521 ` I forgot to mention modafinil, though I was discussing it with a friend who had an iatrogenic embolic stroke.
https://tandfonline.com/doi/full/10.1080/08923973.2019.1669045
https://pubmed.ncbi.nlm.nih.gov/15652995/
Looks promising for post-viral fatigue if mediated in part by elevated NF-κB signaling and suppressed orexin activity.
# Concerns
## Flu Vaccine Safety
https://mobile.reuters.com/article/amp/idUSKBN2760NA?__twitter_impression=true