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julia326 committed Oct 10, 2017
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Vaxrank is a tool for selecting mutated peptides for use in personalized therapeutic cancer vaccination. Vaxrank determines which peptides should be used in a vaccine from tumor-specific somatic mutations, tumor RNA sequencing data, and a patient's HLA type. Additionally, Vaxrank considers surrounding non-mutated residues in a peptide to prioritize vaccine peptide candidates and improve the odds of successful synthesis.

Vaxrank is being actively developed at the Icahn School of Medicine at Mount Sinai as part of the Genetics and Genomic Sciences program.
Vaxrank is being actively developed at the Icahn School of Medicine at Mount Sinai.

Questions, Bug Reporting, and Issue Tracking
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Vaxrank uses `PyEnsembl <https://github.com/hammerlab/pyensembl>`_ for accessing information about the reference genome. You must install an Ensembl release corresponding to the reference genome associated with the mutations provided to Vaxrank.

The latest release for GRCh38 is Ensembl 87:
The latest supported release for GRCh38 is Ensembl 87:

.. code-block:: bash
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