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Golgi_HCN1s.channel.nml
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Golgi_HCN1s.channel.nml
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<?xml version="1.0" encoding="ISO-8859-1"?>
<neuroml xmlns="http://www.neuroml.org/schema/neuroml2"
xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
xsi:schemaLocation="http://www.neuroml.org/schema/neuroml2 https://raw.github.com/NeuroML/NeuroML2/development/Schemas/NeuroML2/NeuroML_v2beta4.xsd"
id="GolgiHCN1s">
<notes>Channel file containing a single Channel description</notes>
<ionChannel id="GolgiHCN1s" conductance="10pS" type="ionChannelHH" species="h">
<notes>HCN1 channel - slow component of the double exponential, based on mod file by S Solinas, L Forti, E DAngelo. </notes>
<annotation>
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="GolgiHCN1s">
<bqmodel:isDescribedBy xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
<rdf:Bag>
<rdf:li>Solinas S, Forti L, Cesana E, Mapelli J, De Schutter E, D'Angelo E. (2007) Computational reconstruction of pacemaking and intrinsic electroresponsiveness in cerebellar Golgi cells. Front Cell Neurosci. 2007;1:2.</rdf:li>
<rdf:li rdf:resource="http://www.ncbi.nlm.nih.gov/pubmed/18946520"/>
</rdf:Bag>
</bqmodel:isDescribedBy>
</rdf:Description>
</rdf:RDF>
</annotation>
<gate id="s" type="gateHHtauInf" instances="1">
<q10Settings type="q10ExpTemp" q10Factor="3" experimentalTemp="33 degC"/>
<!--timeCourse type="Golgi_HCN1s_tau" tC="0.01451" tD="-4.056 mV" tE="2.302585092 per_mV"/-->
<!--steadyState type="Golgi_HCN1s_oinf" rA="0.002096 per_mV" rB="0.97596" midpoint="-72.49mV" scaleC="0.11305 per_mV"/-->
<timeCourse type="Golgi_HCN1s_tau"/>
<steadyState type="Golgi_HCN1s_oinf" />
</gate>
</ionChannel>
<ComponentType name="Golgi_HCN1s_oinf" extends="baseVoltageDepVariable">
<!--Parameter name="rA" dimension="per_voltage"/-->
<!--Parameter name="rB" dimension="none"/-->
<!--Parameter name="midpoint" dimension="voltage"/-->
<!--Parameter name="scaleC" dimension="per_voltage"/-->
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<!--DerivedVariable name="x" exposure="x" dimension="none" value=" (rA * v + rB) * 1/(1 + exp((v - midpoint)*scaleC )) "/-->
<DerivedVariable name="x" exposure="x" dimension="none" value=" (1 - (0.002096 *V + 0.9759)) * 1/(1 + exp((V + 72.49)*0.11305 )) "/>
</Dynamics>
</ComponentType>
<ComponentType name="Golgi_HCN1s_tau" extends="baseVoltageDepTime">
<!--Parameter name="tC" dimension="none"/-->
<!--Parameter name="tD" dimension="voltage"/-->
<!--Parameter name="tE" dimension="per_voltage"/-->
<Constant name="TIME_SCALE" dimension="time" value="1 ms"/>
<Constant name="VOLT_SCALE" dimension="voltage" value="1 mV"/>
<Dynamics>
<!--DerivedVariable name="t" exposure="t" dimension="time" value="TIME_SCALE * exp( ((tC*v) - tD)* tE)"/-->
<DerivedVariable name="V" dimension="none" value="v / VOLT_SCALE"/>
<DerivedVariable name="t" exposure="t" dimension="time" value="TIME_SCALE * (exp (((0.01451 * V) + 4.056 )* 2.302585092 ))"/>
</Dynamics>
</ComponentType>
</neuroml>