Is it necessary to create memory streams instead of buffers to cache large files?

[turone]

https://github.com/HowProgrammingWorks/ServeStatic/blob/f170cd47c3c73689dc6bbaca9d58fea0bc31b33f/JavaScript/3-cache/server.js#L49C16-L49C16
In the lecture, you said that when there is a large file in the buffer, then returning it via "res.end(data)" will block the reception or processing of new requests from the client.
Then the question arises: is it enough to simply send the buffer through "res.write(data)" or is it necessary to create memory streams and then output them through "data.pipe(res)"?
https://youtu.be/n_AdKIzbpBc?list=LL&t=1934