Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

cca result #8

Open
yuan596 opened this issue Aug 27, 2021 · 0 comments
Open

cca result #8

yuan596 opened this issue Aug 27, 2021 · 0 comments

Comments

@yuan596
Copy link

yuan596 commented Aug 27, 2021

hello,I have a question.
image
These words are mentioned in the literature:'CCA projections of mass cytometry clusters and bulk RNA-seq genes. First two canonical variates (CVs) separated genes upregulated in leukocyte-rich RA from genes upregulated in OA. HLA-DR genes are highly associated with THY1+CD34−HLA-DRhi by mass cytometry.' 'CCA revealed that greater abundance of THY1+CD34−HLA-DRhi fibroblasts measured via mass cytom�etry is associated with higher expression of IL6, CXCL12, and HLA-DRA in bulk RNA-seq of the same samples, suggesting that these cells are in an active cytokine-producing state (Fig. 4h).’
I don‘t know how to make these conclusions?

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

1 participant