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DESCRIPTION
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DESCRIPTION
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Package: posologyr
Title: Individual Dose Optimization using Population Pharmacokinetics
Version: 1.2.4
Authors@R: c(
person("Cyril","Leven",role = c("aut", "cre","cph"),
email = "cyril.leven@chu-brest.fr",
comment = c(ORCID = "0000-0002-0697-4370")),
person("Matthew","Fidler",role = c("ctb"),
email="matthew.fidler@gmail.com",
comment = c(ORCID = "0000-0001-8538-6691")),
person("Emmanuelle","Comets",role = c("ctb")),
person("Audrey","Lavenu",role = c("ctb")),
person("Marc","Lavielle",role = c("ctb"))
)
Description: Determine individual pharmacokinetic (and
pharmacokinetic-pharmacodynamic) profiles and use them to personalise drug
regimens. You provide the data and a population pharmacokinetic model,
'posologyr' provides the individual a posteriori estimate and allows you to
determine the optimal dosing. The empirical Bayes estimates are computed as
described in Kang et al. (2012) <doi:10.4196/kjpp.2012.16.2.97>.
License: AGPL-3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.1
Depends:
R (>= 3.5.0)
Imports:
rxode2,
stats,
mvtnorm,
data.table
Suggests:
lotri,
knitr,
rmarkdown,
testthat (>= 3.0.0),
ggplot2,
magrittr,
tidyr
URL: https://levenc.github.io/posologyr/, https://github.com/levenc/posologyr
BugReports: https://github.com/levenc/posologyr/issues
VignetteBuilder: knitr
Config/testthat/edition: 3