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Beginners manual #343
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There is documentation at: https://umap-learn.readthedocs.io/en/latest/ that can ideally get you started. If that isn't quite what you are after I would be happy to hear more about what sort of guide would be helpful to people. |
I have RNA-seq expression and global DNA methylation data on 24 patients and would like to see how they cluster based on these two parameters. I have been running PCA and basic cluster analysis on each RNA-seq and methylation separately but would like to integrate them into one image. Any suggestions as to where to start. Thanks |
For combining datasets you could look into techniques discussed in this issue: #58 Beyond that I don't have a great deal of expertise in the sorts of data you have, so I can't offer much beyond the documentation I already linked. If you are using sklearn for the PCA and clustering then swapping in UMAP should be relatively straightforward. |
Also see: https://github.com/lmcinnes/umap/tree/master/notebooks for some examples |
Closing due to inactivity |
I have installed both versions, 0.3.10 and 0.2.4, for "umap-learn". Is there a good beginners manual to get me started yet. Thanks
Dave
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