Applying clusterpval in single cell data

[ghost]

Hi Lucy,

I am interested in using your statistical model to test gene expression differences between clusters.
My input is a matrix where: columns correspond to cells, rows to genes. Usually I would apply a (row-wise) wilcox test in order to check if the mean expression of one group of cells (belonging to a cluster) is significantly higher/lower than in the other group. This way, I can obtain a list of genes significantly up/down regulated between these two groups.

I have been testing your clusterpval tool but I am not sure how to apply it in cases like this. Can you help me?

Best,
Coral

[lucylgao]

Hi Coral, please see my answer to a similar question here: #3