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Imputation considers only NaN; should it also consider zeros? #231

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acesnik opened this issue Aug 18, 2023 · 0 comments
Open

Imputation considers only NaN; should it also consider zeros? #231

acesnik opened this issue Aug 18, 2023 · 0 comments

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@acesnik
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acesnik commented Aug 18, 2023

Is your feature request related to a problem? Please describe.
I was getting some mysterious negative log2-transformed values after imputation, and it took me a while to figure out that zeros aren't being imputed. I changed them to NaN, and now they're being imputed.

Describe the solution you'd like
Adding a parameter for the preprocessing engine for which values to impute. Or change the default behavior to imputing both zeros and NaN are imputed.

Describe alternatives you've considered
I found a workaround with converting zeros to NaN before running imputation.

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