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coverage across multiple samples for binning #44

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franciscozorrilla opened this issue May 16, 2024 · 1 comment
Open

coverage across multiple samples for binning #44

franciscozorrilla opened this issue May 16, 2024 · 1 comment

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@franciscozorrilla
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Hello, thanks for developing this tool.

In the metacoag paper you write:

MetaCoAG can be easily extended to work with other metagenomics assemblers. In the future, we plan to extend MetaCoAG to support overlapped binning [24] (i.e., contigs may belong to multiple species) and multi-sampled binning [27] (i.e., integration across multiple samples instead of co-assembly).

I am wondering if the current implementation of metacoag supports input coverage across multiple samples for binning?

Best,
Francisco

@Vini2
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Vini2 commented Jun 7, 2024

Hi @franciscozorrilla,

Thanks for your interest in MetaCoAG.

Yes, MetaCoAG supports input coverage across multiple samples for binning. You can generate coverage files for each sample using a tool such as CoverM and combine those into one abundance file using the combine_cov.py script.

Please let me know if you have any further questions.

Thanks,
Vijini

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