research.bib

@book{Nestler2013,

author = {Dennis Sharney and Eric J. Nestler},
publisher = {Oxford University Press},
isbn = {978–0–19–993495–9},
pages = {1259},
title = {{Neurobiology of mental illness}},
year = {2013}
}

@article {Caspi2003,
	author = {Caspi, Avshalom and Sugden, Karen and Moffitt, Terrie E. and Taylor, Alan and Craig, Ian W. and Harrington, HonaLee and McClay, Joseph and Mill, Jonathan and Martin, Judy and Braithwaite, Antony and Poulton, Richie},
	title = {Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene},
	volume = {301},
	number = {5631},
	pages = {386--389},
	year = {2003},
	doi = {10.1126/science.1083968},
	publisher = {American Association for the Advancement of Science},
	journal = {Science}
}


@article {Wong2004,
	author = {Ma Li Wong and Julio Licinio},
	title = {From monoamines to genomic targets: a paradigm shift for drug discovery in depression},
	volume = {3},
	pages = {136--151},
	year = {2004},
	doi = {10.1038/nrd1303},
	publisher = {Nature Reviews Drug Discovery},
}


@book{Jane2017,

author = {Mary Jane Tacchi and Jan Scott},
publisher = {Oxford University Press},
isbn = {978-0-19-955865-0},
pages = {91},
title = {{Depression: A very short introduction}},
year = {2017},
}


@article {Nemeroff2005,
	author = {Charles B. Nemeroff and Wylie W. Vale},
	title = {The Neurobiology of Depression: Inroads to Treatment and New Drug Discovery},
	volume = {66},
	pages = {5--13},
	year = {2005},
	publisher = {The Journal of Clinical Psychiatry},
}


@book{Stahl,

author = {Stephen M. Stahl},
publisher = {Cambridge University Press},
isbn = {978-1-107-02598-1},
pages = {},
title = {{Stahl’s essential psychopharmacology : neuroscientific basis and practical application}},
year = {2013},
}


@book{Kandel,

author = {Eric R. Kandel and James H. Schwartz and Thomas M. Jessell and Steven A. Siegelbaum and A.J. Hudspeth},
publisher = {Mc Graw Hill Medical},
isbn = {978-0-07-139011-8},
pages = {},
title = {{Principles of Neural Science}},
edition = {4},
year = {2013},
}

@Article{Kim,

author = {Sang Won Jeon and Yong Ku Kim},
title = {Molecular Neurobiology and Promising New Treatment in Depression},
journal = {International Journal of Molecular Sciences},
volume = {17},
year = {2016},
number = {3},

}

@article {Charney2004,

author = {Dennis S. Charney and Husseini K. Manji},
title = {Life Stress, Genes, and Depression: Multiple Pathways Lead to Increased Risk and New Opportunities for Intervention},
volume = {2004},
number = {225},
year = {2004},
publisher = {Science Signaling},
}

@article{Raison2006,

author = {Charles L. Raison and Lucile Capuron and Andrew H. Miller},
title = {Cytokines sing the blues: inflammation and the pathogenesis of depression},
journal = {Trends in Immunology},
volume = {27},
number = {1},
pages = {24--31},
year = {2006},
}

@article{Raison2009,

author = {Andrew H. Miller and Vladimir Maletic and Charles L. Raison},
title = {Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression},
journal = {Biological Psychiatry},
volume = {65},
number = {9},
pages = {732--741},
year = {2009},
}

@article{Souza2006,

author = {Sérgio Filipe Sousa and Pedro Alexandrino Fernandes and Maria João Ramos},
title = {Protein–ligand docking: Current status and future challenges},
journal = {Proteins: Structure, Function, and Bioinformatics},
volume = {65},
number = {1},
pages = {15-26},
year = {2006},
}

@article{Perola2004,

author = {Emanuele Perola and W. Patrick Walters and Paul S. Charifson},
title = {A detailed comparison of current docking and scoring methods on systems of pharmaceutical relevance},
journal = {Proteins: Structure, Function, and Bioinformatics},
volume = {56},
number = {2},
pages = {235-249},
year = {2004},
}

@Article{Pagadala2017,

author= {Nataraj S. Pagadala and Khajamohiddin Syed and Jack Tuszynski},
title= {Software for molecular docking: a review},
journal= {Biophysical Reviews},
year= {2017},
volume= {9},
number= {2},
pages= {91--102},
}

@article{Autodock1998, 

  author = {Garrett M. Morris and  David S. Goodsell and  Robert S. Halliday and  Ruth Huey and  William E. Hart and  Richard K. Belew and Arthur J. Olson}, 
  title = {{Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function}}, 
  pages = {1639--1662}, 
  number = {14}, 
  volume = {19}, 
  journal = {Journal of Computational Chemistry}, 
  year = {1998},
}

@book{Cramer2004,

author = {Cristopher J. Cramer},
publisher = {John Wiley \& Sons},
isbn = {0–470–09181–9},
pages = {105},
title = {{Essential of computational chemistry: theories and models}},
year = {2004},
}

@article{Autodock2016, 

  author = {Stefano Forli and Ruth Huey and Michael E. Pique and Michel F. Sanner and David S. Goodsell and Arthur J. Olson}, 
  title = {{Computational protein–ligand docking and virtual drug screening with the AutoDock suite}}, 
  pages = {905--919}, 
  volume = {11}, 
  journal = {Nature Protocols}, 
  year = {2016},
}

@article{Durrant2011, 

  author = {Jacob D. Durrant and J. Andrew McCammon}, 
  title = {{Computational protein–ligand docking and virtual drug screening with the AutoDock suite}}, 
  number = {71},
  volume = {9}, 
  journal = {BMC Biology}, 
  year = {2011}
}

@article{Klengel2013, 

  author = {Torsten Klengel and Divya Mehta and Christoph Anacker and Monika Rex-Haffner and Jens C. Pruessner and Carmine M. Pariante and Thaddeus W. W. Pace and Kristina B. Mercer and Helen S. Mayberg and Bekh Bradley and Charles B. Nemeroff and Florian Holsboer and Christine M. Heim and Kerry J. Ressler and Theo Rein and Elisabeth B. Binder }, 
  title = {{Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions}}, 
  volume = {16}, 
  pages = {33--41},
  journal = {Nature Neuroscience}, 
  year = {2013},
}

@book{Schatzberg2015,

author = {Alan F. Schatzberg and Charles DeBattista},
publisher = {American Psychiatric Publishing},
isbn = {978–1–58562–481-2},
pages = {48--50},
title = {{Manual of clinical psychopharmacology}},
year = {2015},
}

@article{Nestler2006, 

  author = {Olivier Berton and Eric J. Nestler}, 
  title = {{New approaches to antidepressant drug discovery: beyond monoamines}},
  volume = {7}, 
  pages = {137--151},
  journal = {Nature Reviews Neuroscience}, 
  year = {2006},
}

@article{Belmaker2008, 

  author = {R. H. Belmaker and Galila Agam}, 
  title = {{Major Depressive Disorder}},
  volume = {358}, 
  number = {1},
  pages = {55--68},
  journal = {New England Journal of Medicine}, 
  year = {2008},
}


@article{Iwata2016, 

  author = {Eric S. Wohleb and Tina Franklin and Masaaki Iwata & Ronald S. Duman}, 
  title = {{Integrating neuroimmune systems in the neurobiology of depression}},
  volume = {17}, 
  number = {8},
  pages = {497--511},
  journal = {Nature Reviews Neuroscience}, 
  year = {2016},
}

@misc{WHO2017,
    author = {\relax{World Health Organization}},
	TITLE = "Depression and Other Common Mental Disorders: Global Health Estimates",
	NOTE = "Geneva, 2017."
}

@book{DSM5,

author = {\relax{American Psychiatric Association}},
publisher = {American Psychiatric Publishing},
isbn = {978-0-89042-554-1},
pages = {165},
title = {{Diagnostic and statistical manual of mental disorders: DSM-5}},
year = {2013},
}

@article{Dawlati2010, 

  author = {Yekta Dowlati and Nathan Herrmann and Walter Swardfager and Helena Liu and Lauren Sham and Elyse K. Reim and Krista L. Lanctôt},
  title = {{A Meta-Analysis of Cytokines in Major Depression}},
  volume = {67}, 
  number = {5},
  pages = {446--457},
  journal = {Biological Psychiatry}, 
  year = {2010},
}

@article{Yang2012, 

  author = {Yang Liu and Roger Chun-Man Ho and Anselm Mak},
  title = {Interleukin (IL)-6, tumour necrosis factor alpha (TNF-$\alpha$) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression},
  volume = {139}, 
  number = {3},
  pages = {230--239},
  journal = {Journal of Affective Disorders}, 
  year = {2012},
}

@article{Miller2016, 

  author = {D. R. Goldsmith and M. H. Rapaport and B. J. Miller},
  title = {A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression},
  volume = {21}, 
  number = {12},
  pages = {1696--1709},
  journal = {Molecular Psychiatry}, 
  year = {2016},
}

@article{Kappelmann2018, 

  author = {N. Kappelmann and G. Lewis and R. Dantzer and P. B. Jones and G. M. Khandaker},
  title = {Antidepressant activity of anti-cytokine treatment: a systematic review and meta-analysis of clinical trials of chronic inflammatory conditions},
  volume = {23}, 
  number = {2},
  pages = {335--343},
  journal = {Molecular Psychiatry}, 
  year = {2018},
}


@article{Evolution2016, 

  author = {Andrew H. Miller and Charles L. Raison},
  title = {The role of inflammation in depression: from evolutionary imperative to modern treatment target},
  volume = {16}, 
  number = {1},
  pages = {22--34},
  journal = {Nature Reviews Immunology}, 
  year = {2016},
}

@article{Dantzer2008, 

  author = {Robert Dantzer and Jason C. O'Connor and Gregory G. Freund and Rodney W. Johnson and Keith W. Kelley },
  title = {From inflammation to sickness and depression: when the immune system subjugates the brain},
  volume = {9}, 
  number = {1},
  pages = {46--56},
  journal = {Nature Reviews Neuroscience}, 
  year = {2008},
}

@article{Pittenger2008, 

  author = {Christopher Pittenger and Ronald S. Duman},
  title = {Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms},
  volume = {33}, 
  number = {1},
  pages = {88--109},
  journal = {Neuropsychopharmacology}, 
  year = {2008},
}

@article{Eyre2012, 

  author = {Harris Eyre and Bernhard T. Baune},
  title = {Neuroplastic changes in depression: A role for the immune system},
  volume = {37}, 
  number = {9},
  pages = {1397--1416},
  journal = {Psychoneuroendocrinology}, 
  year = {2012},
}

@article{Leeson2007, 

  author = {Paul D. Leeson and Brian Springthorpe },
  title = {The influence of drug-like concepts on decision-making in medicinal chemistry},
  volume = {6}, 
  number = {11},
  pages = {881--890},
  journal = {Nature Reviews Drug Discovery}, 
  year = {2007},
}

@article{Nestler2008, 

  author = {Vaishnav Krishnan and Eric J. Nestler },
  title = {The molecular neurobiology of depression},
  volume = {455}, 
  number = {7215},
  pages = {894--902},
  journal = {Nature}, 
  year = {2008},
}

@phdthesis{Kiametis2012,
    title    = {Modelagem molecular de potenciais candidatos a inibidores da acetilcolinesterase},
    school   = {Universidade de Brasília},
    author   = {Alessandra Sofia Kiametis},
    pages = {76}
    year     = {2012}, %other attributes omitted
}

@phdthesis{Silva2017,
    title    = {Modelos preditivos baseados em descritores moleculares e modos de interação receptor-ligante para inibidores de Acetilcolinesterase},
    school   = {Universidade de Brasília},
    author   = {Mônica de Abreu Silva},
    pages = {143}
    year     = {2017}, %other attributes omitted
}

@book{Cooper2003,

author = {Jack R. Cooper and Floyd E. Bloom and Robert H. Roth},
publisher = {Oxford University Press},
isbn = {0-19-514007-9},
pages = {357-393},
title = {{The biochemical basis of neuropharmacology}},
year = {2003},
edition = {8},
}

@article{Scheller2011, 

  author = {Jürgen Scheller and Athena Chalaris and Dirk Schmidt-Arras and Stefan Rose-John},
  title = {The pro- and anti-inflammatory properties of the cytokine interleukin-6},
  volume = {1813}, 
  number = {5},
  pages = {878--888},
  journal = {Biochimica et Biophysica Acta - Molecular Cell Research}, 
  year = {2011},
}

@article{Spooren2011, 

  author = {Anneleen Spooren and Krzysztof Kolmus and Guy Laureys and Ralph Clinckers and Jacques De Keyser and Guy Haegeman and Sarah Gerlo},
  title = {Interleukin-6, a mental cytokine},
  volume = {67}, 
  number = {1},
  pages = {157--183},
  journal = {Brain Research Reviews}, 
  year = {2011},
}

@article{Johnson2018, 

  author = {Daniel E. Johnson and Rachel A. O'Keefe and Jennifer R. Grandis },
  title = {Targeting the IL-6/JAK/STAT3 signalling axis in cancer},
  volume = {15}, 
  number = {4},
  pages = {234--248},
  journal = {Nature Reviews Clinical Oncology}, 
  year = {2018},
}

@article {Varghese2002,

	author = {Varghese, J. N. and Moritz, R. L. and Lou, M.-Z. and van Donkelaar, A. and Ji, H. and Ivancic, N. and Branson, K. M. and Hall, N. E. and Simpson, R. J.},
	title = {Structure of the extracellular domains of the human interleukin-6 receptor $\alpha$-chain},
	volume = {99},
	number = {25},
	pages = {15959--15964},
	year = {2002},
	journal = {Proceedings of the National Academy of Sciences},
}

@article{Ramanchandran2003,

author = {Lovell, Simon C. and Davis, Ian W. and Arendall III, W. Bryan and de Bakker, Paul I. W. and Word, J. Michael and Prisant, Michael G. and Richardson, Jane S. and Richardson, David C.},
title = {Structure validation by C$\alpha$ geometry: $\Phi$, $\Psi$ and C$\Beta$ deviation},
journal = {Proteins: Structure, Function, and Bioinformatics},
volume = {50},
number = {3},
pages = {437-450},
year = {2003},
}

@article{Lanquillon2000,

title = {Cytokine Production and Treatment Response in Major Depressive Disorder},
journal = {Neuropsychopharmacology},
volume = {22},
number = {4},
pages = {370--379},
year = {2000},
author = {S. Lanquillon and J.C. Krieg and U. Bening-Abu-Shach and H. Vedder},
}

@article{Jones2015,

title = {IL-6 as a keystone cytokine in health and disease},
journal = {Nature Immunology},
volume = {16},
number = {5},
pages = {448--457},
year = {2015},
author = {Christopher A. Hunter and Simon A. Jones},
}

@article{Willett2006,

title = {Similarity-based virtual screening using 2D fingerprints},
journal = {Drug Discovery Today},
volume = {11},
number = {23},
pages = {1046 - 1053},
year = {2006},
author = {Peter Willett},
}

@article{Kitchen2004,

title = {Docking and scoring in virtual screening for drug discovery: methods and applications},
journal = {Nature Reviews Drug Discovery},
volume = {3},
number = {11},
pages = {935 - 949},
year = {2004},
author = {Douglas B. Kitchen and Hélène Decornez and John R. Furr and Jurgen Bajorath},
}

@article{Eckert2007,

title = {Molecular similarity analysis in virtual screening: foundations, limitations and novel approaches},
journal = {Drug Discovery Today},
volume = {2},
number = {5"},
pages = {225 - 233},
year = {2007},
author = {Hanna Eckert and Jurgen Bajorath},
}

@book{Dirac1958,

    author = {P. A. M. Dirac},
    publisher = {Oxford University Press},
    pages = {13-16},
    title = {{The principles of quantum mechanics}},
    year = {1958},
    edition = {4},
}

@article{Taylor2002,

    title = {A review of protein-small molecule docking methods},
    journal = {Journal of Computer-Aided Molecular Design},
    volume = {16},
    number = {3},
    pages = {151 - 166},
    year = {2002},
    author = {R. D. Taylor and P. J. Jewsbury and J. W. Essex},
}

@article{Vina2010,

    author = {Trott, Oleg and Olson, Arthur J.},
    title = {AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading},
    journal = {Journal of Computational Chemistry},
    volume = {31},
    number = {2},
    pages = {455-461},
    year = {2010}
}

@article{Yuriev2015,

    author = {Yuriev, Elizabeth and Holien, Jessica and Ramsland, Paul A.},
    title = {Improvements, trends, and new ideas in molecular docking: 2012–2013 in review},
    journal = {Journal of Molecular Recognition},
    volume = {28},
    number = {10},
    pages = {581-604},
    year = {2015},
}

@book{Goldberg1989,

    author = {Goldberg, David E.},
    title = {Genetic Algorithms in Search, Optimization and Machine Learning},
    year = {1989},
    isbn = {0201157675},
    publisher = {Addison-Wesley Longman Publishing Co., Inc.},
    edition = {1},
}

@article{Simon2011,

    author = {Simon A. Jones AND Jürgen Scheller AND Stefan Rose-John},
    journal = {The Journal of Clinical Investigation},
    publisher = {The American Society for Clinical Investigation},
    title = {Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling},
    year = {2011},
    volume = {121},
    pages = {3375-3383},
    number = {9},
}

@article{Stefan2012,

    author = {Rose-John, Stefan},
    journal = {International journal of biological sciences},
    publisher = {The American Society for Clinical Investigation},
    title = {IL-6 trans-signaling via the soluble IL-6 receptor: importance for the pro-inflammatory activities of IL-6},
    year = {2012},
    volume = {8},
    pages = {1237-1247},
    number = {9},
}

@article{Kirchmair2008,

    author = {Johannes Kirchmair AND Patrick Markt AND Simona Distinto AND Gerhard Wolber AND Thierry Langer},
    journal = {Journal of Computer-Aided Molecular Design},
    publisher = {Springer},
    title = {Evaluation of the performance of 3D virtual screening protocols: RMSD comparisons, enrichment assessments, and decoy selection—What can we learn from earlier mistakes?},
    year = {2008},
    volume = {22},
    pages = {213-228},
    number = {3},
}

@article{Bursulaya2003,

    author = {Badry D. Bursulaya AND Maxim Totrov AND Ruben Abagyan AND Charles L. Brooks},
    journal = {Journal of Computer-Aided Molecular Design},
    publisher = {Springer},
    title = {Comparative study of several algorithms for flexible ligand docking},
    year = {2003},
    volume = {17},
    pages = {755-763},
    number = {11},
}

@article {Benkovic2003,
	author = {Stephen J. Benkovic AND Sharon Hammes-Schiffer},
	title = {A Perspective on Enzyme Catalysis},
	volume = {301},
	number = {5637},
	pages = {1196--1202},
	year = {2003},
	publisher = {American Association for the Advancement of Science},
	journal = {Science},
}

@article {Gaali2015,
	author = {Steffen Gaali AND Alexander Kirschner AND Serena Cuboni AND Jakob Hartmann, Christian Kozany AND Georgia Balsevich AND Christian Namendorf AND Paula Fernandez-Vizarra AND Claudia Sippel AND Anthony S. Zannas AND Rika Draenert AND Elisabeth B Binder AND Osborne F. X. Almeida AND Gerd Rühter AND Manfred Uhr AND Mathias V Schmidt AND Chadi Touma AND Andreas Bracher AND Felix Hausch },
	title = {Selective inhibitors of the FK506-binding protein 51 by induced fit},
	volume = {11},
	number = {1},
	pages = {33--37},
	year = {2015},
	publisher = {Nature Chemical Biology},
}