abnormal syncytia formation

[yongqunh]

Preferred term label:
abnormal syncytia formation

https://en.wikipedia.org/wiki/Syncytium

Synonyms
abnormal syncytium
abnormal symplasm

Definition (free text, please give PubMed ID)
An abnormal formation of syncytium or symplasm, a multinucleate resulting from multiple cell fusions of uninuclear cells (i.e., cells with a single nucleus).

note: this is found in COVID-19:
https://www.embopress.org/doi/full/10.15252/embj.2020106267

Parent term (use hpo.jax.org/app)

Diseases characterized by this term ? (e.g. Orphanet or OMIM number)

SARS-CoV-2
https://www.embopress.org/doi/full/10.15252/embj.2020106267
(note: this is the term we would like to use in CIDO but it does not exist in HPO yet)

Your nano-attribution (ORCID)
http://orcid.org/0000-0001-9189-9661 (Oliver He)

Anthony Huffman and Oliver He

[pnrobinson]

I think this is a little outside the scope of HPO, which is for clinical phenotypes. I think that this is an experimental observation that is not used at all in clinical contexts. I am not sure where the correct place is for this -- possibly it should go directly into Coronavirus Infectious Disease Ontology?

[yongqunh]

I see. thanks.