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How to model relations between EC, Rhea, and GO #783

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cthoyt opened this issue Feb 2, 2024 · 0 comments
Open

How to model relations between EC, Rhea, and GO #783

cthoyt opened this issue Feb 2, 2024 · 0 comments

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@cthoyt
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cthoyt commented Feb 2, 2024

As suggested by Chris in biopragmatics/pyobo#168 (comment), I am bringing this to the RO issue tracker. I want to use well-defined RO properties to model the relationships between reactions in Rhea, molecular functions in GO, and gene products in EC so I can fill out all of the blanks in the following diagram. Further, we know of a protein that 1) has the molecular function, 2) catalyzes the reaction, 3) is an instance of the enzyme class in this diagram, so I also want to figure out the right way to annotate those.

Can RO do the following:

  1. Let me know what relations exist that are appropriate for this
  2. Help me mint new relations with appropriate semantics to cover the remaining

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